LOCUS       DAVBED010000001        83337 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBED010000001 DAVBED010000000
VERSION     DAVBED010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.001"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..164
                     /locus_tag="VQ547_000001"
     CDS             <1..164
                     /locus_tag="VQ547_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2541939.1"
                     /translation="YNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIA
                     GIINHELGF"
     gene            232..480
                     /locus_tag="VQ547_000002"
     CDS             232..480
                     /locus_tag="VQ547_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541940.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            611..1783
                     /locus_tag="VQ547_000003"
     CDS             611..1783
                     /locus_tag="VQ547_000003"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2541941.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1783..3057
                     /locus_tag="VQ547_000004"
     CDS             1783..3057
                     /locus_tag="VQ547_000004"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2541942.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3093..4058)
                     /locus_tag="VQ547_000005"
     CDS             complement(3093..4058)
                     /locus_tag="VQ547_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2541943.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4039..5493)
                     /locus_tag="VQ547_000006"
     CDS             complement(4039..5493)
                     /locus_tag="VQ547_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2541944.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5870..7753
                     /locus_tag="VQ547_000007"
     CDS             5870..7753
                     /locus_tag="VQ547_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2541945.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7902..8789
                     /locus_tag="VQ547_000008"
     CDS             7902..8789
                     /locus_tag="VQ547_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2541946.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9109..9726)
                     /locus_tag="VQ547_000009"
     CDS             complement(9109..9726)
                     /locus_tag="VQ547_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2541947.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10141..10329)
                     /locus_tag="VQ547_000010"
                     /pseudo
     CDS             complement(10141..10329)
                     /locus_tag="VQ547_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10839..10919)
                     /locus_tag="VQ547_000011"
                     /pseudo
     CDS             complement(10839..10919)
                     /locus_tag="VQ547_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11035..11928
                     /locus_tag="VQ547_000012"
     CDS             11035..11928
                     /locus_tag="VQ547_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2541948.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11925..13124
                     /locus_tag="VQ547_000013"
     CDS             11925..13124
                     /locus_tag="VQ547_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2541949.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13477..14244)
                     /locus_tag="VQ547_000014"
     CDS             complement(13477..14244)
                     /locus_tag="VQ547_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541950.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14261..14956)
                     /locus_tag="VQ547_000015"
     CDS             complement(14261..14956)
                     /locus_tag="VQ547_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2541951.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14961..15326)
                     /locus_tag="VQ547_000016"
     CDS             complement(14961..15326)
                     /locus_tag="VQ547_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2541952.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15466..15939
                     /gene="nrdR"
                     /locus_tag="VQ547_000017"
     CDS             15466..15939
                     /gene="nrdR"
                     /locus_tag="VQ547_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2541953.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15940..17109
                     /locus_tag="VQ547_000018"
     CDS             15940..17109
                     /locus_tag="VQ547_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2541954.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17110..18006
                     /gene="dnaI"
                     /locus_tag="VQ547_000019"
     CDS             17110..18006
                     /gene="dnaI"
                     /locus_tag="VQ547_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2541955.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            18003..18716
                     /locus_tag="VQ547_000020"
     CDS             18003..18716
                     /locus_tag="VQ547_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2541956.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18730..20040
                     /gene="der"
                     /locus_tag="VQ547_000021"
     CDS             18730..20040
                     /gene="der"
                     /locus_tag="VQ547_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2541957.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20131..20466
                     /locus_tag="VQ547_000022"
     CDS             20131..20466
                     /locus_tag="VQ547_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541958.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20606..20941
                     /locus_tag="VQ547_000023"
     CDS             20606..20941
                     /locus_tag="VQ547_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541959.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21126..21917
                     /locus_tag="VQ547_000024"
     CDS             21126..21917
                     /locus_tag="VQ547_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541960.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21910..22551
                     /locus_tag="VQ547_000025"
     CDS             21910..22551
                     /locus_tag="VQ547_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541961.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22555..23205
                     /locus_tag="VQ547_000026"
     CDS             22555..23205
                     /locus_tag="VQ547_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2541962.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23216..23503
                     /locus_tag="VQ547_000027"
     CDS             23216..23503
                     /locus_tag="VQ547_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541963.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23649..26162
                     /gene="secA"
                     /locus_tag="VQ547_000028"
     CDS             23649..26162
                     /gene="secA"
                     /locus_tag="VQ547_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2541964.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26243..27274
                     /locus_tag="VQ547_000029"
     CDS             26243..27274
                     /locus_tag="VQ547_000029"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2541965.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27276..28307
                     /locus_tag="VQ547_000030"
     CDS             27276..28307
                     /locus_tag="VQ547_000030"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2541966.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28346..28714
                     /locus_tag="VQ547_000031"
     CDS             28346..28714
                     /locus_tag="VQ547_000031"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2541967.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28704..29807
                     /locus_tag="VQ547_000032"
     CDS             28704..29807
                     /locus_tag="VQ547_000032"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2541968.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29826..31841
                     /gene="recG"
                     /locus_tag="VQ547_000033"
     CDS             29826..31841
                     /gene="recG"
                     /locus_tag="VQ547_000033"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2541969.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32157..33137
                     /locus_tag="VQ547_000034"
     CDS             32157..33137
                     /locus_tag="VQ547_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2541970.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33942..34169
                     /locus_tag="VQ547_000035"
     CDS             33942..34169
                     /locus_tag="VQ547_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541971.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34457..37354
                     /gene="nanA"
                     /locus_tag="VQ547_000036"
     CDS             34457..37354
                     /gene="nanA"
                     /locus_tag="VQ547_000036"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2541972.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38369..38821
                     /locus_tag="VQ547_000037"
     CDS             38369..38821
                     /locus_tag="VQ547_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2541973.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38840..40177
                     /locus_tag="VQ547_000038"
     CDS             38840..40177
                     /locus_tag="VQ547_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2541974.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40256..41140
                     /locus_tag="VQ547_000039"
     CDS             40256..41140
                     /locus_tag="VQ547_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2541975.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41140..41973
                     /locus_tag="VQ547_000040"
     CDS             41140..41973
                     /locus_tag="VQ547_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2541976.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41991..44084
                     /gene="nanB"
                     /locus_tag="VQ547_000041"
     CDS             41991..44084
                     /gene="nanB"
                     /locus_tag="VQ547_000041"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2541977.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44096..45199
                     /locus_tag="VQ547_000042"
     CDS             44096..45199
                     /locus_tag="VQ547_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2541978.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45373..46071
                     /locus_tag="VQ547_000043"
     CDS             45373..46071
                     /locus_tag="VQ547_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2541979.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            46090..47607
                     /locus_tag="VQ547_000044"
     CDS             46090..47607
                     /locus_tag="VQ547_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2541980.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47732..49060
                     /locus_tag="VQ547_000045"
     CDS             47732..49060
                     /locus_tag="VQ547_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2541981.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49312..50178
                     /locus_tag="VQ547_000046"
     CDS             49312..50178
                     /locus_tag="VQ547_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2541982.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50194..51033
                     /locus_tag="VQ547_000047"
     CDS             50194..51033
                     /locus_tag="VQ547_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2541983.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51306..51758
                     /locus_tag="VQ547_000048"
     CDS             51306..51758
                     /locus_tag="VQ547_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2541984.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51855..52199
                     /locus_tag="VQ547_000049"
     CDS             51855..52199
                     /locus_tag="VQ547_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2541985.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52483..53127
                     /locus_tag="VQ547_000050"
     CDS             52483..53127
                     /locus_tag="VQ547_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2541986.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53296..54213
                     /locus_tag="VQ547_000051"
     CDS             53296..54213
                     /locus_tag="VQ547_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2541987.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54231..55115
                     /locus_tag="VQ547_000052"
     CDS             54231..55115
                     /locus_tag="VQ547_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2541988.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(55131..55982)
                     /locus_tag="VQ547_000053"
     CDS             complement(55131..55982)
                     /locus_tag="VQ547_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2541989.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56182..58239
                     /gene="pbp2b"
                     /locus_tag="VQ547_000054"
     CDS             56182..58239
                     /gene="pbp2b"
                     /locus_tag="VQ547_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2541990.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58250..58846
                     /gene="recR"
                     /locus_tag="VQ547_000055"
     CDS             58250..58846
                     /gene="recR"
                     /locus_tag="VQ547_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2541991.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            59022..60065
                     /locus_tag="VQ547_000056"
     CDS             59022..60065
                     /locus_tag="VQ547_000056"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2541992.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            60149..61522
                     /locus_tag="VQ547_000057"
     CDS             60149..61522
                     /locus_tag="VQ547_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2541993.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61509..62120
                     /locus_tag="VQ547_000058"
     CDS             61509..62120
                     /locus_tag="VQ547_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2541994.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62211..62915
                     /locus_tag="VQ547_000059"
     CDS             62211..62915
                     /locus_tag="VQ547_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2541995.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            63134..64507
                     /gene="ftsA"
                     /locus_tag="VQ547_000060"
     CDS             63134..64507
                     /gene="ftsA"
                     /locus_tag="VQ547_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2541996.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64524..65783
                     /gene="ftsZ"
                     /locus_tag="VQ547_000061"
     CDS             64524..65783
                     /gene="ftsZ"
                     /locus_tag="VQ547_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2541997.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65788..66459
                     /locus_tag="VQ547_000062"
     CDS             65788..66459
                     /locus_tag="VQ547_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2541998.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66469..67008
                     /locus_tag="VQ547_000063"
     CDS             66469..67008
                     /locus_tag="VQ547_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2541999.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            67008..67271
                     /locus_tag="VQ547_000064"
     CDS             67008..67271
                     /locus_tag="VQ547_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2542000.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67268..67952
                     /locus_tag="VQ547_000065"
                     /pseudo
     CDS             67268..67952
                     /locus_tag="VQ547_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67961..68749
                     /gene="divIVA"
                     /locus_tag="VQ547_000066"
     CDS             67961..68749
                     /gene="divIVA"
                     /locus_tag="VQ547_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2542001.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            69097..71889
                     /locus_tag="VQ547_000067"
     CDS             69097..71889
                     /locus_tag="VQ547_000067"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2542002.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72299..72661
                     /locus_tag="VQ547_000068"
     CDS             72299..72661
                     /locus_tag="VQ547_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542003.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73196..73888
                     /locus_tag="VQ547_000069"
     CDS             73196..73888
                     /locus_tag="VQ547_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2542004.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73941..76352
                     /locus_tag="VQ547_000070"
     CDS             73941..76352
                     /locus_tag="VQ547_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2542005.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76602..77303
                     /locus_tag="VQ547_000071"
     CDS             76602..77303
                     /locus_tag="VQ547_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542006.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77305..80005
                     /locus_tag="VQ547_000072"
                     /pseudo
     CDS             77305..80005
                     /locus_tag="VQ547_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(80101..80592)
                     /gene="tpx"
                     /locus_tag="VQ547_000073"
     CDS             complement(80101..80592)
                     /gene="tpx"
                     /locus_tag="VQ547_000073"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2542007.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80715..81644)
                     /gene="psaA"
                     /locus_tag="VQ547_000074"
     CDS             complement(80715..81644)
                     /gene="psaA"
                     /locus_tag="VQ547_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2542008.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81676..82524)
                     /locus_tag="VQ547_000075"
     CDS             complement(81676..82524)
                     /locus_tag="VQ547_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2542009.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82521..83243)
                     /locus_tag="VQ547_000076"
     CDS             complement(82521..83243)
                     /locus_tag="VQ547_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2542010.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25199 a        15194 c        18399 g        24545 t
ORIGIN      
        1 cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
       61 aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
      121 tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
      181 ctactttcct tattgtctgt aaatctactg accttgttgt ttatcccagt catggtttct
      241 agttcgggct cagagtttca aagtggatgg caagagcatc aattgattgc tgagaaggtt
      301 agtaaaacac ttgataagac atttgataag gatgtcagag aaattccgac cagtcagttt
      361 tatcaaaaat ttgtagatga gatgggaagg atttactcag gaaatttgat cctccaggag
      421 ctgataactg tgaatggagc ttataaagct acttatatcg gtgaactctc tagcaactaa
      481 tcattcttta aaatgatgac caataagagg cttgatttgg tgaatcaagt cttttttctc
      541 tcttttactg ccatttgtga taaaatagta tagaacgatt ttttacatga atgataaaac
      601 agaggtaaat atgacaatcg gtattgataa gattggtttt gcgaccagtc aatatgtctt
      661 gaaattacaa gacttagcag aagcgagggg aattgaccct gaaaaattaa gtaaaggact
      721 cttactcaag gaattgagta ttgcgcccct aactgaggac atcgtgacct tggcggccag
      781 tgctagtgac tctattttaa ctgagcaaga aagacaagaa gttgacatgg tcattgtggc
      841 taccgagtca ggaattgacc agagtaaggc tgcggccgtc tttgtgcatg gcttgctggg
      901 catccagccc tttgctcgta gtttcgagat taaagaagcc tgctatgggg cgacagctgc
      961 cctccattat gccaaattgc atgtggaaaa ttctccggag tccaaggtct tggtcattgc
     1021 cagtgatatt gccaaatatg gtattgaaac tccgggagaa ccaactcaag gtgctggaag
     1081 tgtagctatg ttgattacac aaaatccacg catgatggcc tttaataatg acaatgtagc
     1141 tcagacccgt gacatcatgg atttctggcg accaaattac tcgacaactc cttatgtaaa
     1201 tggtgtctat tctacccaac aatacttgga tagtttgaaa acgacttggc ttgaatatca
     1261 aaaacgctac cagcttactc tggatgattt tgcggctgtt tgtttccact tgccttatcc
     1321 taaattagcg ctaaaaggct tgaaaaaaat catggataag agcctgcctc aagagaaaaa
     1381 agacctctta caaaagcatt ttgaccagtc tattctctac agtcaaaagg tggggaatat
     1441 ctacacaggt tcacttttcc ttggactttt gtctctcttg gaaaatgcag atagcttgaa
     1501 agctggggat aaaatcgccc tttatagtta cggaagtgga gctgtggctg agttcttcag
     1561 tggtgaattg gttgaaggat atgaagctta tttggataaa gaccgcttga acaagctcaa
     1621 ccaacgaact gccttatccg ttgcagacta tgaaaaggtc ttttttgagg aagtaaactt
     1681 ggatgaaaca aactctgccc agtttgctgg ctatgaaaat caagattttg ccttggttga
     1741 aattctcgac caccaacgcc gttatagcaa ggttgaaaaa taatgaagat aagttggaat
     1801 ggattttcta aaaaatcata ccaagagcgc ctcgagctgt taaaagctca ggcgctcctt
     1861 agtcctgaga gacaagctag tctggagaag gatgaacaga tgagtgtgac tgtggcagac
     1921 cagctgagtg agaatgtagt gggaactttt tctctgcctt attcgctggt tccggaggta
     1981 cttgtcaacg gtcaggaata caccgttccc tatgtgacag aagaaccctc tgtggttgcg
     2041 gcggccagct atgccagcaa aatcatcaag cgtgcaggtg gttttactgc acaagtccat
     2101 cagcgccaga tgattgggca ggtagccctt tatcaagttg ctaatcctaa actagcgcaa
     2161 gagaagattg ccagcaagaa agcggagctc ttggagtttg ccaatcaagc ctatccttct
     2221 atcgttaaac gtggaggtgg ggcgcgtgat ctgcatgtcg agcagataaa aggcgaacca
     2281 gactttctcg ttgtttatat tcatgtcgat acccaggaag ccatgggtgc caatatgctc
     2341 aacaccatgc tggaagcctt gaaaccagtc ttagaagaac tcagtcaggg acagagtctc
     2401 ataggaatcc tgtccaacta cgcgaccgat tctctggtga ctgcaagctg tcgcatggcc
     2461 tttcgctact tgagccgcca aaaggatcaa ggacgagaga ttgcggagaa aattgcgttg
     2521 gctagtcagt ttgcgcaggc tgatccttac cgagctgcta ctcataataa aggaattttt
     2581 aatggtattg atgcgatttt gattgccact ggtaatgact ggcgtgccat cgaagctggg
     2641 gcccatgcct ttgccagtcg agatggacgc tatcaaggtc ttagttgctg gacgctggac
     2701 cttgaaagag aagaattggt cggtgagatg accctgccca tgcctgtagc gactaagggt
     2761 ggctctatcg gcctcaaccc acgtgtagct ttcagtcatg atctactagg aaatccttct
     2821 gccagagaat tagcccagat tatcgtgtcc atcggtcttg cccaaaattt tgcagccctc
     2881 aaagctttgg taagtacggg catccagcaa ggccacatga aactacaggc caaatcccta
     2941 gctctcctag ctggggctag tgaatctgaa gttgctcccc tagtagagcg cctcatctca
     3001 gataaaacct ttaacctaga gacagcccag cgctatctcg aaaatttaag atcataaaaa
     3061 actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg taatagtgta
     3121 actggtaaga agtaaccagt tgtggcaact tccttgcctt caatcttttg caagagaaga
     3181 tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa ttgagggtag
     3241 taattttcga taaagtaggt cccatcatag ccgatgacct tgagctcttt tgggacagaa
     3301 atgcccaatt cttgagcgat tttaatgacc agaatagctg tcaaatcatc cgaagcaaaa
     3361 atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatttcttt tctgacggga
     3421 gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc aaaaccagcg
     3481 tggcgtagtc cggttggcga attggaattg tcattccctg taatcatgat gatagtctgg
     3541 gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt gtcagaggag
     3601 acgacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc tgtcacacga
     3661 ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtccac ctgattggct
     3721 tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt gcagatgatg
     3781 gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc tgcatagaaa
     3841 acattggaaa tattagggaa aatcaagccg attaacttag ctgattttcc ttgcagacta
     3901 cgagccaggt tgttgggttt atagcccaat tctcgcatgg cttcattgac tttttggatg
     3961 gttttctcag atagataccc ttttttattg ataacccgag aaacggtagt aggactgacg
     4021 cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat agtaagttcc
     4081 agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga agacacgacc
     4141 agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat cgatgaagat
     4201 tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa attcttgggc
     4261 atactgttct ccagcctggc tacgatccac tgtcacttga ccgtttacaa ggtcaaagtt
     4321 gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct ggctattagc
     4381 ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg agaaggcttc
     4441 ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct tgtcgtcttt
     4501 gatagtgagt tccttgacca aagagaaggt tccttggtgg tcaaaacggt cagatgggta
     4561 agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag gagcgttgaa
     4621 ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag acacatctac
     4681 cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg gaaagatatt
     4741 atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga caggatgttc
     4801 ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt tagcaaagtc
     4861 aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt agagacggac
     4921 gaagcctttt ttctccaagt cctgtccacc gacgacagca tagtattgac ttttaaagtt
     4981 aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa tcaagatctt
     5041 gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatctggt atgggtgacg
     5101 gatccagttt tcatcgcgaa catttcctgt ataaaatagg aataagttat cgccaaattg
     5161 catggcagaa ccagagtagg caccgtggct atctaatgga gtatctggta aaactttgat
     5221 tccagtttct ttaaagtgaa ccaaatcatc actttctagc tgtgcccaag atttcaaacc
     5281 gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat caaagtaaga
     5341 aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat gagtatgcca
     5401 tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc aatcttgata
     5461 aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc ttatcacttt
     5521 taatagtaac tgttttcgat aaaaaatgca agccttttat gttaaaaaag aggaaaaact
     5581 gtcaaacgat tatcataaaa taaatacagg aaatcaatca aatttttacg aaaatgtgaa
     5641 agataatgaa ataaaagact ttttaaccaa ggtttcaaac ttatttttca aggaattcct
     5701 gatgaaacag tcaaaaacaa tcaatctaaa acttgcccac taagtggata gaatattttt
     5761 tctgcaaaac gcttgacata tttttaaaac atgataaaat aatagtcgta agggcgaata
     5821 aaatcgcttt caaacaagaa caaaatgtta tataaggaga tttttgcaaa tgaacaatca
     5881 ggaaattgca aaaaaagtca tcgatgcctt gggcggacgt gaaaatgtca atagtgttgc
     5941 ccactgtgcg actcgtctac gtgtcatggt caaagatgaa gagaaaatca ataaagaagt
     6001 gattgagaac ttggaaaaag ttcaaggtgc tttctttaac tcagggcaat accaaattat
     6061 ctttggtaca ggtacagtta acaaaatgta cgatgaagtt gttgtacttg gcttaccaac
     6121 atcatctaag gatgacatga aagcagaagt tgctaaacaa gggaactggt tccaacgtgc
     6181 tatccgtact ttcggtgatg ttttcgttcc aatcatccca gttatcgtag cgacaggtct
     6241 cttcatgggt gtgcgtggtc ttttcaacgc tcttgaaatg ccacttccag gtgactttgc
     6301 aacttacaca caaatcttga cagatacagc cttcatcatc ttgccaggtt tggttgtgtg
     6361 gtcaaccttc cgtgtatttg gtggaaatcc tgccgttggt atcgttcttg gtatgatgct
     6421 tgtctctggc tcacttccaa acgcttgggc agttgctcaa ggtggtgaag taacagcgat
     6481 gaacttcttt ggtttcatcc ctgttgttgg tttgcaaggt tccgttcttc cagccttcat
     6541 catcggggtt gtcggagcta aatttgaaaa agctgtccgc aaggttgttc cagatgtcat
     6601 tgacctcttg gtaacaccat tcgtgacact tttggtcatg tctatccttg gactctttgt
     6661 cattggacca gttttccacg ttgttgaaaa ctacatcctt attgctacaa aagcgattct
     6721 tagcatgcca tttggtcttg gtggtttctt gattggtggg gttcaccaat tgatcgtcgt
     6781 gtcaggtgtg caccacatct tcaacttgct tgaagtgcaa ttacttgctg ctgaccatgc
     6841 taacccattc aacgctatca tcacagctgc tatgacagct caaggtgctg ctactgttgc
     6901 ggttggtgtt aaaacaaaaa atccaaaact gaaaacactt gctttcccgg ctgctctttc
     6961 tgccttccta ggtattacag agcctgctat cttcggggtg aacttgcgct tccgtaaacc
     7021 attcttcctt tcattgattg ctggtgcaat cggtggtgga ttggcttcta tccttggact
     7081 tgctggtact ggtaatggta tcaccatcat ccctggtaca atgctttatg ttggtaacgg
     7141 acaacttcca caataccttc ttatggtagc tgtatcattt gcccttggtt ttgctcttac
     7201 ttacatgttt ggttacgaag atgaagtaga cgcaactgca gctgcaaaac aagctgaagt
     7261 ggctgaagaa aaagaagaag ttgcgccagc agctcttcaa aatgaaacac ttgtaactcc
     7321 tatcgtcggt gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct caagtggagc
     7381 tatgggacaa ggtatcgctg tgaaaccaag tcaaggcgtg gtctatgcac tagctgatgc
     7441 tgaagtttca attgcctttc caacagggca cgcttttggt ttgaaaacaa gaaatggtgc
     7501 tgaagttttg attcacgttg gtattgacac tgtatctatg aacggtgacg gttttgaagc
     7561 aaaagttgct caaggtaata aggtgaaagc tggcgatgtt cttggaacat ttgactcaaa
     7621 caaaatcgct gcagctggac ttgatgatac aacaatggtt atcgttacaa atacagctga
     7681 ctacgcttca gtagctccag tcgcaacagg ttcagtttcg aagggggatg ctgtgatcga
     7741 agtgaaaatc taatcaatcc tctctaatgt gaaaacgaac aaatgacatg tttgttcgtt
     7801 tttattagat agtaagattt acagaggaaa atctaaaaaa tagagacatt tagactttcg
     7861 aagtatgcta taataaagaa aataaaaaca agaggtttat catgacaaaa ttatatggaa
     7921 gcttggaagc gggcggtaca aagtttgtct gtgctgtcgg tgatgaaaac tttaacgttg
     7981 tagaaaaaac acaatttcca acaacaactc caatcgaaac aatcgataaa accattgagt
     8041 tcttctcaaa attcgataac cttgctggtc ttgcagttgg ttcatttggg ccgattgata
     8101 ttgacaaaaa ctcaaaaact tatggcttta tcacgacgac tccaaaacca aactgggcaa
     8161 atgtggactt gcttggtgcc cttcgtcgcg ccctaaacgt gccaatgtac ttcacaacag
     8221 acgtaaacag ctctgcttac ggtgaaatgg ttgctcgtaa caatgctggt ggtcgtatcg
     8281 aaaacttggt ttactacaca atcggtacag gtatcggtgc aggcgtcatc caacgtggtg
     8341 agtttatcgg tggtgtgggt caccctgaaa tgggtcatta ttatgttgct agacacccaa
     8401 tggatattga aaaagagttt aagggtgttt gtcctttcca taagggatgt ctagaaggtt
     8461 atgcagctgg taccagtttg gaagctcgta caggtgtacg tggggaaact attgaactca
     8521 acaaccctgt ttgggatgtt caagcctact atatcgctca agctgcggtt aatgcgacag
     8581 tgactttccg cccagacgtg attgtctttg gtggaggggt catggctcaa caacatatgc
     8641 tggaccgtgt ccgtgagaaa tttacatctc ttcttaatgg ttacctacca gtaccagatg
     8701 tgcgtgacta tatcgtgacg ccagcagtcg caggaaatgg ttctgccaca cttgggaact
     8761 ttgttcttgc aaaagaagtt tcaaaataaa gcacaaaatc cgcttgggaa accaaacgga
     8821 ttttgtggtt gaaaacaata tttttgagcc tttccttaag tgattacgga cggtagcgac
     8881 tttcttcgaa attccatacc taaactttga gcctagtgtc tcaaagtttc cgaatacctg
     8941 aaaccattag atttcaggtg tttctatcac ggcggaaagg ctaggtaagt cctcgcctca
     9001 ctatcgaaaa atatgcataa tttccatacc aaagtatatt tagtatcaag ctatagttaa
     9061 tctacgcttt aaaaatccac ttgggaaacc aaacggattt tttacgtgtc aaagcatttg
     9121 ccagaaaaag tcaataatat aggtcagacc gtaggtataa accacgaggg taaagggttt
     9181 ggtcagaatg atgatagtca tgtagcgctt gaaactcatc ttggtcaggg cggccagcat
     9241 acagagaaag tcagctgggc taatgggcca aatcatcata aaaataaaga agcggtcaaa
     9301 acgattgccc ttatctagcc agccgatgta cttgtcgtag gtgcgcttgc tgacgacaga
     9361 ctggacaaag gcagctccgt ataggcgcac tagataaaag ataatggcac agccaatcac
     9421 gatgccgata tagttgtaga tagtcccgat gatgtgcccg tagataaaga ccccagccac
     9481 cgaggtcaag gcccctggaa tgatagggac gacagtctgt aaaatctgta aaaagataaa
     9541 gagaggtgga ccccagatgc ctgcctgctg gataaaggca gagagggttt ccttggattg
     9601 taaaatccca gcctgataag cccaaataca gaaaatcaaa ctcccaaccc caccgacaat
     9661 cgatgagata ttgataactc gctgcagaag gggagaaaca gctttcattt gtttatcctg
     9721 tgacatgtaa actcctcata gatagtatat ttctactata ccatattttg gaggagaaag
     9781 ggggaatgag tcttttttga taaggaatag aaagtaaata gcccttcgag acttagaata
     9841 ggtctgtcaa ctaaaggtta tatgcattct aggtttcgaa taatcgcaat tccataaatt
     9901 taaaagtatt ctaagtttcg aatagcttat ctgagataat tttgaggcat tcgcgctttc
     9961 gaatagtcat tttccctaaa gtttatatgt attctgaagc tagaaagact aaaatataaa
    10021 agtagtaaga gtctctctct gatggacgta atttatggct agtatgaatc ctttgaattg
    10081 ttagttaatt ttaatattaa tcagttctga aataattact aaatatagtt agatggtgag
    10141 ttaattattg ctaaatttca agttcaagtt agtcatccag aagtcttctc tgggggactt
    10201 gtagttcaag cattttttag gatagttgtt aatccacttt tcgataaatg cgacttcctt
    10261 tgtagttgtt ttcttagttc cctgaggtaa ccatctatga atgagcctgt tgtgattttc
    10321 attagatcct atagtgatgt gcataataga tatagcagat tgaaactaga atagtataca
    10381 tctacttcta aaacattgtt agaaatcaat ttgactgtcc tgatcaattt gtcctgtttt
    10441 tatttcattt tactatataa tccttagaaa acatatcgga caagcggttg aattccgttc
    10501 cgtccattag tagataaagg attactcctt cttgaaatga cagatgaact tgtttcttat
    10561 aaaaatgttg tctgaaacta ttagcctttt tccagaagtt ttagaggaag aaaactttac
    10621 gaggaaaaag gagttactca aataacaatt caggattaaa aatagacagt tgaggagcgg
    10681 aaggtataaa ttaagtttgc tactgtataa tggatttatc actaatactc ttcgaaaatc
    10741 tcttcaaacc acgtcagctt cgccttgccg tagatatagt tactgacttc gtcagttcta
    10801 tccacaacct caaaacagtg ttttgagctg acttcgtcag ttttatctgc aacctcaaag
    10861 ctgtactttg agcagcctac ggctagcttc ctagtttgct ctttgctttt cattgagtat
    10921 aaaagtgctc caggccatat tttacacagc aatagtcttc taaaaatgga caaaaacatt
    10981 gtaaaggcta tcaaaaagga gtataatgag tgcaagaaat ttcggaggtg aaagatgcta
    11041 gaagtaagaa gtctagagaa aagttttggc tccaagcaag ttttgtttgg tattgacttt
    11101 caagcgcgac caggtcgtat tttgggacta gtcggaaaaa atggtgctgg aaaaacaacg
    11161 attttccata gtattttgaa attcctagaa tatcagggag aaatcggtct ggatggtcag
    11221 gatattcgtc aggagaccta tgctcggatt ggttatctgc ctgaagaacg cagtctcatg
    11281 cctaaattga cagttcttga acaagttcgc tacttggcga ctctaaaagg catggatgcc
    11341 aaagaagtca aagaaaaact ccctcaatgg atgaagaggt tggaagtgaa aggaaagctg
    11401 acagataaaa tcaagagtct gtcaaaagga aatcagcaga agattcagct cattattact
    11461 ctgattcatg aaccagacct gattatcttg gatgagcctt ttagtggatt ggacccagtt
    11521 aatacagaat tgctcaaaca agtcattttt caggaaaaag agcgcggagc aaccattatc
    11581 ttttctgacc atgtcatgac caatgttgag gaactttgtg acgatattct gatgatccga
    11641 gatggccgtg tggtcttgca cggaccagtt caggatgtcc gcaatcaata cgggaaaacg
    11701 cgtctctttg tttcaagtga acgaagcaag gaagaattgg aaaatcttcc tcatgtcaaa
    11761 caggtgagct tgaccaaaca aggcagttgg aaattgattt tggaggatga gagcgctgga
    11821 agggaactct tcccaatctt gactcaaggt caatatatcg caacatttga ccaacaagcg
    11881 ccaactatcg atgaaatctt taaactagaa tcaggagtgg aagtatgaga aatatgtggg
    11941 ttgtaatcaa ggaaacctat cttcgacatg tcgagtcatg gagtttcttc tttatggtga
    12001 tttcgccgtt cctcttttta ggaatctctg taggaattgg gcatctccaa ggttcttcta
    12061 tggctaaaaa taataaagtg gcagtagtga caacagtgcc atctgtagca gaaggactga
    12121 agaatgtaaa tggtgttaac ttcgactata aagacgaagc aagtgccaaa gaagcaatta
    12181 aagaagaaaa attaaaaggt tatttgacca ttgatcaaga agatagtgtt ctaaaggcag
    12241 tttatcatgg cgaaacatcg cttgaaaatg gaattaaatt tgaggttaca ggtacactca
    12301 atgaactgca aaatcagctt aatcgttcaa ctgcttcctt gtctcaagag caggaaaaac
    12361 gcttagagca gacaattcaa ttcacagaaa agattgatga agccaaggaa aataaaaagt
    12421 ttattcaaac aattgcagca ggtgccttag gattctttct ttatatgatt ctgattacct
    12481 atgcgggtgt aacagctcag gaagttgcca gtgaaaaagg caccaaaatt atggaagtcg
    12541 ttttttctag cataagggca agtcactatt tctatgcgcg gatgatggct ctgtttctag
    12601 tgattttaac gcatattggg atctatgttg taggtggtct ggctgccgtt ttgctcttta
    12661 aagatttgcc attcttggct cagtctggta ttttggatca cttgggagat gctatctcac
    12721 tgaatacctt gctctttatt ttgatcagtc ttttcatgta cgtagtcttg gcagcattcc
    12781 taggatctat ggtttctcgt cctgaggact cagggaaagc cttgtcgcct ttgatgattt
    12841 tgattatggg tggttttttt ggagtgacag ctctaggtgc agctggtgac aatctcctct
    12901 tgaagattgg ttcttatatt ccctttattt cgaccttctt tatgccgttt cgaacgatta
    12961 atggctatgc ggggggagca gaagcatgga tttcacttgc tattacagtg atttttgcgg
    13021 tggtagcaac aggatttatc ggacgcatgt atgctagtct cgttcttcaa acggatgatt
    13081 tagggatttg gaaaaccttt aaacgtgcct tatcttataa atagaagagc cttgcgaaag
    13141 cgaggttttt aaaggtgaaa agggtggaat cacgaaccta atgatgtaca cattatgtaa
    13201 acaggttgct tgaaaactca attgtatagt gaactgaatc tggaatagga taatattact
    13261 tctaaaacat tcttataaat tgatttgaat tccaaaatcc catcgttccg ttcttatttc
    13321 attttgcgat atagtgaaag gaaataagtc agctcacaaa aaacgcataa tatcaaggat
    13381 ttttaacact tgatactatg cgttttctaa ttttaaagac tttttgcctg gtctcttttg
    13441 ttctatgagt atgttacata tctaggtaaa aattatttaa agcaaattaa ccttatttct
    13501 caagatgtag taggttccga gataaaagat agctatgaat atgagttctt taacaatggc
    13561 tatacctgct cccatataga aatggtcatt gagtcctacc agtgaattga catagaaatt
    13621 agaactaaga ttgaagaaaa gttcaataaa tccaatgacg atttggatac caatgtaggc
    13681 tgcaacagcg agtgctgtac ggtattcatt gaaaagctgt ccaatggaaa tagccaggta
    13741 gatgcagagg attcctgaaa tggtatttag taggaaggat atacctgtaa gaaagatctg
    13801 agggagatgt gtttctacaa atgtaatcac ataagaaaga ggaatccatt ctggagctgt
    13861 taaagccaga ataataacag cacttagagc caatacagcg gtgctaatca atgaccagat
    13921 aaaggcaccg attagtttgg ctgtgatgat atggtgttca gaaactggca aggtcaaagt
    13981 cagatagcct tgtcggtcgt agacactacc tttgaagcgt ttaataatca agaaaatggt
    14041 tgaaatcgca agtgtaagca tcaagccacc aaagactgta gctagaaaaa gtagcatagt
    14101 agcctgactt tcttggtaag gtagattttt aaagccttgt gtctgtattc cgatgagggc
    14161 agaaaggact agcacggctg cgtagagggc taaataccac ttgttaacat ttttaaattc
    14221 gtagtgaact aaattccaaa acataaataa tctcctttgc ttaggcctta aattcctgac
    14281 ggaagagttg gtcaatggat tcacctgact cgtagcgaat atcatctaca tttccttgac
    14341 ggacgacttt tccgtctttt aggaagacaa tttcatccaa gattggctcg atatcagaaa
    14401 tcaagtgggt agaaatcaaa acggtagaag ttggtgagta gttgttgata atggtattga
    14461 ggatataagc acgggctgct ggatccaccc caccaatggg ttcatccaaa acatagagac
    14521 gagcatcacg gctcataacc aaaatcagtt gaaccttttc tttgtttcct tttgatagtt
    14581 tcttgagacg actattttca tcaatgccca ggtctgcaag tagatgatga gcgcgttcaa
    14641 gattgaaatc tttatagaag gtcttgaagt aggttagggc ttctttgacc ttcatttgct
    14701 cattgagata ggtcgtatca ggcaaataag ctacaacggc cttggttgct gggcttgggt
    14761 ccatgtcgtt gatgaggaca cgtccttgat ctggttgtaa gaggccatta attagtttaa
    14821 tcagggttgt ttttcctgag ccgtttggcc caagaaggcc gacaattttt ccagctggaa
    14881 tgtcaagaga aacattttca agggctggtg ttgctccata tgatttggat acattttcaa
    14941 atactagtaa tgacataggc ttaaactcct ttaatataat cactgactac gcctggtagt
    15001 tcttcttttt catagccaaa atggatcatg gaggaaacga agtgttccaa ttcttcttct
    15061 gataattgtt tgcgtgactg agcgattagc tccttatcct tagtcacaaa tcgtccagtt
    15121 gttcgcttgc tgtagacaaa tccttctcgt tcaaggtctg ataaggctct ttggatggta
    15181 ttgggattga caccagcctc gctagctagc tccctcacgg ttggaagttg ttgattgggt
    15241 tccagtgtat gggaaacaat ctgaagcttg attttctcca taatctgtaa atagatgggt
    15301 tttttgttgt caaatgtcca ggacatctta gtctcctttc tcttatcctt ttgtcttaac
    15361 taaataatac aacaaaacaa aaaacttgtc aagcaaaaag aagaattgtt ttgggaatcg
    15421 cttaaaaaat ggtataatga aaagaaaacg ataaggaggg aaaggatgcg ttgtccaaaa
    15481 tgtggggcta ccaagtcaag tgttatcgat agtcgccaag cagaagaagg gaacaccatt
    15541 cgtagaagac gtgagtgcga cgaatgccaa caccgtttta caacctacga acgagtagaa
    15601 gaaagaacct tagtggttgt taaaaaagat ggtacacggg aacaattctc cagagataaa
    15661 atctttaatg ggattatccg ctcagcccag aaacgtcctg tgtcaagtga tgaaatcaac
    15721 atggtagtca atcgtatcga acagaaactc cgtggtcgaa atgaaaatga aattcaaagt
    15781 gaggacattg gttcactcgt catggaggag ttggctgaat tggacgagat tacctatgta
    15841 cgttttgcta gtgtctatcg tagttttaag gatgtcagtg agttagagag cttgctccaa
    15901 caaatcaccc agtcctctaa aaagaaaaag gaaagataaa tgaagccaat tgaccgtttt
    15961 tcttatctaa agaataatcg ggtgtcgcaa gatacctcat ctctggtaca gtgctacctc
    16021 ccgattatcg gtcaggaggc actgagcctt tatctttata caatcagttt ttgggataat
    16081 ggtagaaagg aatatctttt ttcaagtatc ctcaatcatc tcaactttgg gatggataga
    16141 ctgataaaat cattgaaaat cttatctgct tttaatctct tgaccctcta tcaaaagggg
    16201 gatgtttatc agctagccct ccatgctcct ctatctagtc aagacttctt ggagcatcct
    16261 gtttatcgca gactcttaga gaaaaagatt ggcgactctg ctgtggagga tttgaaagtt
    16321 gaaagtgctg atggtgaaga aatacctgtc tcactcaatc aagtctttcc agaattggca
    16381 gaactaggca gtcaagaaga ccttggtctc aagaagaaag tggccaatga ttttgacttg
    16441 gaacattttc gccagctgat ggctcgagat ggacttcgtt ttgcggatga gcagtccgat
    16501 gtcttaaacc tctttgctat tgccgaggag aagaaatgga cttggtttga aacctatcaa
    16561 ttggccaagt caacagctgt ttctcaggtt atttcaacca aacgcatgcg tgaaaaaatt
    16621 gctcaaaaac cagtttcctc tgactttaat cctaaggaag caaccattat caaggaagct
    16681 aaaagtaaga ctgccctgca gttcttagca gaaatcaagc aaacacgcaa ggggaccatt
    16741 acccaaacag aaagagaact tttgcaacag atggctggct tgggcttgct ggacgaagtc
    16801 atcaatatca ttctcttgtt gacctttaat aaggtggatt cggcaaacat caatgagaaa
    16861 tatgccatga aggtggctaa tgactatgcc tatcaaaaga tacattcagc agaagaggcc
    16921 gttttacgaa ttcgtgagcg agggcagaaa acaaaaacac aaaaacagaa tcagactgcc
    16981 ccagcaaaaa ccaatattcc taaatggagt aacccagatt ataagaatga aaccagcgag
    17041 gaaactcgtc tggaactaga acgtaagaaa caagaactat tagctcgatt agaaaaagga
    17101 ggagattaga tggaaagtgt cggagacgta ctcaaacgtc aacccagccg tttttattat
    17161 caagatttgg tccagaaaat catgaaggac cctgatgttg cggcttttat ccagcaagaa
    17221 tccttgactc cagaggaatt aaatcgcagt atctccaagt ttaatcagta catcaccgag
    17281 cgtgacaagt ttctccgtgg ggatacggat tatattgcca aaggctacaa gccgattttg
    17341 gttaagaatc atggctatgc agatgtttca tatgaagaaa ctcctgagct aatcgcggct
    17401 gaaaaagaag cggctattaa gaatcgtctc aagctaatca atctaccagc cagtctcaaa
    17461 aaagctagtt tggctcaagt tgatttggat gatttgggac gcttgccagt ttttgaaaaa
    17521 ctattagcct ttgtggagca atatccagct attcgaaaag gtctttactt atatggagac
    17581 tttggtgtgg gtaaaagttt catggtggcg gccttagctc atgatttatc agaaaaacgt
    17641 ggtgtttcat caactctcct ccactatcct agctttgtca ttgatgtcaa aaatgctatc
    17701 agtgatggca atgttaagac cttggtggat gagattaagc tgtctgaggt cctgatttta
    17761 gatgatattg gcgccgagca atcaaccgct tgggtgcgtg acgaaatcct gcaggtcatt
    17821 ctccaatatc ggatgcagga aaatttaccg acctttttca catccaactt caactttgaa
    17881 gatttggaga agcattttgc gaaagtgaaa catggaaatg acgaaacctg ggaagccaga
    17941 cgggtcatgg aacgcatccg ttatttggct gaggagactc gtttagaagg agtaaaccgt
    18001 cgatgacaga aaccattaaa ttgatgaagg ctcatacttc agtgcgcagg tttaaagagc
    18061 aagaaattcc ccaagtagac ttaaatgaga ttttgacagc agcccagatg gcatcatctt
    18121 ggaagaattt ccaatcctac tctgtgattg tggtacgaag tcaagagaag aaagatgcct
    18181 tgtatgaatt ggtacctcaa gaagccattc gccagtctgc tgttttcctt ctctttgtcg
    18241 gagatttgaa ccgagcagaa aagggagccc gacttcatac cgacaccttc caaccccaag
    18301 gtgtggaagg tctcttgatt agttcggtcg atgcagctct tgctggacaa aacgccttgt
    18361 tggcagctga aagcttgggc tatggtggtg tgattatcgg tttggttcga tacaagtctg
    18421 aagaagtggc agagctcttt aacctacctg actacaccta ttctgtcttt gggatggcac
    18481 tgggtgtgcc aaatcaacat catgatatga aaccgagact gccactagag aatgttgtct
    18541 ttgaggaaga ataccaagaa cagtcaactg aggcaatcca agcttatgac cgtgttcagg
    18601 ctgactatgc tggggcgcgt gcgaccacaa gctggagtca gcgcctagca gaacagtttg
    18661 gtcaagctga accaagctca actagaaaaa atcttgaaca gaagaaatta ttgtagaaag
    18721 tgagaaatta tggccctacc aactattgcc attgtaggac gtcccaatgt tgggaaatca
    18781 accctattta atcggatcgc tggtgagcga atctccattg tagaagatgt cgaaggagtg
    18841 acacgtgacc gtatttatgc aacgggtgag tggctcaatc gttcttttag catgattgat
    18901 acaggaggaa ttgatgatgt cgatgctcct ttcatggaac aaatcaagca ccaggcagaa
    18961 attgccatgg aagaagcaga tgttatcgtc tttgtcgtgt ccggtaagga aggaattacc
    19021 gatgcagacg aatacgtagc ccgtaagctt tataagaccc acaaaccagt tatcctcgca
    19081 gtcaacaagg tggacaaccc tgagatgaga aatgatatct atgatttcta tgctctcggt
    19141 ttgggtgaac cattgcctat ctcatctgtc catggaatcg gtacagggga tgtgctagat
    19201 gcgatcgtag aaaatcttcc aaatgaatat gaggaagaaa atccagatgt cattaagttt
    19261 agcttgattg gtcgtcctaa cgttggaaaa tcaagcttga tcaatgctat cttgggagaa
    19321 gaccgtgtta ttgctagtcc tgttgctgga acaactcgtg atgccattga tacccacttt
    19381 acagatacag atggtcaaga gtttaccatg attgatacgg ctggtatgcg taagtctggt
    19441 aaggtttatg aaaatactga gaaatactct gttatgcgtg ccatgcgtgc tattgaccgt
    19501 tcagatgtgg tcttgatggt catcaatgcg gaagaaggca ttcgtgagta cgacaagcgt
    19561 atcgcaggat ttgcccatga agctggtaaa gggatgatta tcgtggtcaa caagtgggat
    19621 acgcttgaaa aagataacca cactatgaaa aactgggaag aagatatccg tgagcagttc
    19681 caatacctgc cttacgcacc gattatcttt gtatcagctt taaccaagca acgtctccac
    19741 aaacttcctg agatgattaa gcaaatcagc gaaagtcaaa atacacgtat tccatcagct
    19801 gtcttgaacg atgtcatcat ggatgccatt gccatcaacc caacaccgac agacaaagga
    19861 aaacgtctca agattttcta tgcgacccaa gtggcaacca aaccaccaac ctttgtcatc
    19921 tttgtcaatg aagaagaact catgcacttt tcttacctgc gtttcttgga aaatcaaatc
    19981 cgcaaggcct ttgtttttga gggaacaccg attcatctca tcgcaagaaa acgcaaataa
    20041 aaaagtagaa tctggaatga cagttccgga tttttttgat ataataaaat aatagaaaac
    20101 gctatcaaaa gaaggagggt gatgtcggtg atggaacatt tgtttaaatt cttactttta
    20161 gcaccgtact tttattttga taactggatt gagaaggcca acagaaatag taagtttttt
    20221 ccaatttttt attattttta ctggttttac atccccttct attctctttt tagccttgct
    20281 tggacagttg tttcagttct gtttttcaat accgtcttga gaaatgtgac agatatcaag
    20341 ttatggggca tttggtttct ttttattctg ctagctattg gtatgaattg gttaacttat
    20401 tcctgtttca aagaaatgtt tcgcttgaga caggaactag ggaagtctaa gggtggaagg
    20461 cattgattta tatcggtttc tatttgtagg aggtggctta tggtacctct aaaatcattt
    20521 attacacgct attccaaggt ttatattggt aataacattt aatagaacga aactaaagaa
    20581 aacaatttaa aagaggaggt ttgtgatgga atacttgttt aaaatgataa tcttattacc
    20641 ctgtttttac tttttcagct ggattgaaaa ggcaaacaga gatagtaaga ttttcccaat
    20701 tttttactat ttttactgga tttacatcac cctctatgct ctttttagcc ttgcttggac
    20761 agttttttca gttctgtttt tcaatatcgt cttgagaaat ttgacagata tcaagttatg
    20821 gggtatttgg ctattattac tacttatcgc ttttgctagt gactggttag actatatctg
    20881 tttcaaaaaa atgcttgact tgagacggga actagggaag tctaaaggcg gaaggcattg
    20941 atttatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttggat tatatatgta
    21001 actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ttgcggctag
    21061 tttcctagtt tgctctttga ttttcattga gtattatatt actttctatt tgtaggaggt
    21121 ggcttatgaa gattcctctc ttaactttgg caaggcataa atttgtttat gtcttgctta
    21181 ctttgctttt tcttgctttg gtttatcgtg atgttttgat gacttatttc ttttttgata
    21241 ttcatgcgcc cgatctagct aaattcgatg gacaagcaat taaaaatgac ttattaaaat
    21301 cagcattaga ttttcgtatt ctccagttca atctaggttt ttatcaatca tttattattc
    21361 caatcatcat tgttttgcta ggttttcaat atattgagct gaaaaataaa gttttacgat
    21421 tgagtattgg aagagaagtg agctatcaag ggttaaaaag aaagttgact ttgcaagttg
    21481 caagtatccc ttgtttgata tatttagtga ctgtgctgat aattgcaatt ataacctatt
    21541 tctttgggac tttttctcct cttgaatgga attctctatt ttctgatggg agtggtttac
    21601 aaagactcct agatggagag ataaaaagct atttgttctt tacttgtgtc ctactaatcg
    21661 gtattttcat caatgcaatc tattttttac aaatagttga ttatgtgggg aatgtgactc
    21721 gttcggcaat cacctatttg atgtttcttt ggcttggttc tatgctgctc tatagtgcct
    21781 tgccttacta tatggttcct atgacgagtt tgatgcaagc tagctatggg gatgtaagtt
    21841 tgatgaaact ctttactcct tatatccttt atgttgtccc ttatatggta cttaaaaaat
    21901 atgaagataa tgtttaagaa ttttaacaat atttggctaa agagaaagat cgttttacta
    21961 cttcgtatag ttctgatgat gattttgata aactatctat tgtcaacagc ggttcaaaag
    22021 caggatgctg ttatcttttt caagagagaa ttgatttcaa ttttttccta taatgactat
    22081 tctgaagcga atttagaaat ccccaaactc ttgttaaacc tttcgctttt catggtagga
    22141 tggctctctg tcattttact tgaaagtgat ttggcagacc attaccatca cttgattcgc
    22201 tatcaatcaa gctccttttt cgattataca aggaaacgat tggttgtcat ttctaaattt
    22261 tttactcaag atttgtttgt ctggtttctt ggtttacttc cgctaggaat tcatttcaaa
    22321 acagtcgcac ttttcttttt acttgctcag ttaatgatgt tgtacttact actgtcttat
    22381 ctgatagcac tgattagtgc gggcgctggt ttttcttttt ttctctattt tttggcattt
    22441 gtgggacaag aatggatgat ggatcatatt gtaacagtgt atttagtact cttaagctta
    22501 ttagttatgt tgattgttag tcgcttggaa gagaaattta agaaaggata aacgatgaga
    22561 cttgaaatta taaatggaca gaaaatttat gggaaaagac ctattttaaa tcagttgaat
    22621 ttggtgtttc aatcaggaaa aatttatgga cttaaaggtg ataatggatc tggcaagacg
    22681 gttcttttaa agatacttgc tggttatatt aagcttgaca aaggaaaagt tcttcaagat
    22741 ggtaaagttt acggggtaaa aaatcattat attcaggatg caggaatttt aattgaaaaa
    22801 gtcgagtttt tatctcattt atccctgaga gaaaatttgg aactgttaag gtatttttca
    22861 tctaaagtta cggaaaaaag aattgcctat tggattcaat actatgattt acaggaattt
    22921 gaagacgttg aataccgtca tttatccttg ggaacaaagc aaaaaatggc cttgattcaa
    22981 gcctttattt cctctccttc tatactcttt ctcgatgaac ctatgaatgc tttggatgag
    23041 aagagtgtga ggttaaccaa acaggtcatt ttatcttacc tgaaaaaaga aaatggtctg
    23101 gttatcctga cgtcgcacat atcggaagat atttcagacc tttgtacaga tgtattagtt
    23161 gtcgaaaatg gacatataca atatgtaaag gatatacaat cctaggagat ggcttatggc
    23221 acatctaaaa tcatttatta cacgctattc caaggtttat attggtttag ttctgctgat
    23281 ctggctgtct ttcttcttta tcccttggga tagagcgatt ctgggggtaa ggattgacat
    23341 cttcatcatg cagaaaatct tgctagcttt tggaattctg tccattctca tggccttgct
    23401 gtccaagaaa gtcagtctct ttgtttttgg actgatttgc tgtctttctc tttggattaa
    23461 cttatttatc acatttgcca ttttgccgat ttttggcaat taaacagtca taaaagtcgg
    23521 agaggttagc ttgaaaacta acctcttttt ccttttcaaa atggggattc ttccttgaaa
    23581 ataatcagta attgtgctaa aattaaagga acattctaaa atattcggaa tttaaagtaa
    23641 ggaaaaacat ggctaatatt ttaaaaacaa ttatcgaaaa tgataaagga gaaatccgtc
    23701 gtctggaaaa gatggctgac aaggttttca aatacgaaga ccaaatggct actttgactg
    23761 acgaccaact aaaagcaaaa acagttgaat ttaaggaacg ttatcaaaat ggagaatcac
    23821 tggattcatt gctttacgaa gcatttgcgg ttgtccgtga aggtgccaaa cgtgtcctag
    23881 gtctcttccc ttataaggtt caggtcatgg gggggattgt tcttcaccat ggtgacgtgc
    23941 cagagatgcg tacaggggaa gggaaaacct tgactgcgac catgccggta tacctcaatg
    24001 ccctttcagg taaaggggtt cacgtagtta cggttaatga atacctgtca gaacgtgacg
    24061 cgactgagat gggtgaattg tactcttggc ttggtttgtc agtagggatt aacttggcta
    24121 ccaaatctcc aatggagaaa aaagaagcct atgagtgtga tattacttac tcaactaact
    24181 cagaaatcgg atttgactac cttcgtgaca acatggtcgt tcgcgccgaa aacatggtac
    24241 aacgtccgct taactatgcc ttggtcgatg aggttgactc tatcttgatt gacgaggctc
    24301 gtacaccttt gattgtatca ggtgccaatg cggttgaaac cagtcagttg tatcacatgg
    24361 cagaccacta tgtaaaatct ttgaacaaag atgactacat catcgatgtg cagtctaaga
    24421 ctattggttt gtctgattca gggattgaca gggctgaaag ctacttcaaa cttgaaaacc
    24481 tctatgacat cgaaaacgtg gctttgactc actttatcga taacgccctt cgtgccaact
    24541 acatcatgct tctcgatatt gactatgtgg tgagcgaaga gcaagaaatc ttgattgtcg
    24601 accaatttac aggtcgtacc atggaaggtc gtcgttattc tgatggattg caccaagcta
    24661 ttgaagccaa agaaggtgtg ccaatccagg atgaaaccaa gacatctgcc tcaatcacgt
    24721 accaaaacct tttccgtatg tacaagaaat tgtctggtat gacgggtaca ggtaagactg
    24781 aggaagaaga attccgtgaa atctacaaca ttcgtgttat tccaatccca acaaaccgtc
    24841 ctgttcaacg tattgaccac tcagaccttc tttatgcaag tatcgaatct aagtttaaag
    24901 cggttgtcga agacgttaag gctcgttacc aaaagggtca acctgtcttg gttggtacag
    24961 tagcggttga aactagtgac tacatttcta agaaattggt tgcagctggt gttcctcacg
    25021 aagtcttgaa tgccaaaaac cactatagag aagcccaaat catcatgaat gctggtcaac
    25081 gtggtgccgt taccatcgca accaacatgg cgggtcgtgg taccgacatc aagcttggtg
    25141 aaggtgttcg tgaacttgga ggactttgtg ttattggtac agaacgtcat gaaagtcgtc
    25201 gtatcgataa ccagcttcgt ggacgttcag gtcgtcaagg agatccaggt gagtcacaat
    25261 tctacctatc tcttgaagat gatttgatga aacgttttgg ttctgaacgc ttgaagggaa
    25321 tctttgaacg tttgaacatg tctgaagagg cgattgagtc tcgcatgttg acgcgtcagg
    25381 ttgaagcagc tcagaaacgt gtcgaaggaa ataactacga tacccgtaaa caagtccttc
    25441 aatacgatga tgtcatgcgt gaacaacgtg agattatcta tgctcaacgt tacgatgtca
    25501 tcactgcaga tcgtgacttg gcacctgaaa ttcaggctat gatcaaacgc acgattgaac
    25561 gtgtcgttga tggtcatgcg cgtgccaaac aagatgaaaa actagaggca attttgaact
    25621 ttgctaagta caacttgctt cctgaagatt ctattacgat ggaagacttg tcaggcttgt
    25681 ctgataaggc catcaaggaa gagcttttcc aacgtgcctt gaaggtttac gatagtcagg
    25741 tttcaaaact acgcgatgaa gaagcagtta aagaattcca aaaagttttg attctacgag
    25801 tggtggataa caagtggaca gatcatatcg atgcccttga tcaattgcgt aacgcggttg
    25861 gacttcgtgg ctatgctcag aacaaccctg ttgttgagta tcaggcagaa ggtttccgta
    25921 tgtttaatga tatgattggt tcgattgagt ttgatgtgac acgcttgatg atgaaagcac
    25981 aaattcatga acaagaaaga ccacaggcag aacgtcatat cagtacaaca gcgactcgca
    26041 atatcgctgc tcaccaagca agtatgccag aagatttgga tttgagccag attggacgca
    26101 atgaactttg cccatgtggt tctggtaaga aatttaaaaa ctgtcacggt aaaagacaat
    26161 aaaatgagat agtttagagg cggatatctt gtgaaaagta aatttttact gggtatccgt
    26221 ttgctttata aggagatgag ttatggtatt tacagcaaaa agctctaaaa taaatataga
    26281 agaagttcgt gccttgtcaa aattagaagg tcaggctttg gagaggaaat cacagcgcga
    26341 tcaagagcta gaagccatta tacgtggaga agatcagcga attctcttgg taatcgggcc
    26401 atgctcatct gacaacgaag aagctgtcct tgaatacgct aagcgtttgg cagtcctaca
    26461 agaagaagtg gcagatcgta tctttatggt tatgcgtgtt tatactgcca aaccccgtac
    26521 caacggagat ggctataagg gcttgattca ccagcctaac gcgacagaag cgcctagtct
    26581 tatcaatgga atcaaagccg ttcgccatct tcactatcgt gtcatcacag aaacagggat
    26641 gacaactgct gatgaaatgc tttatcctga aaaccttccg cttgtagatg atttgatttc
    26701 ttacatggca gttggtgccc gttcagttga agaccagcaa caccgctttg tggcaagtgg
    26761 ggcaggattt tctactggtt ttaaaaatcc aacctctgga aatctcaatg tcatgtttaa
    26821 tgggatttat gctgctcaaa acaaacaaag tttccttttc ttaggaaaag aagtagaaac
    26881 aactgggaac ccgctttcac acgctattct tcgtggtgct cttaatgagt atggaaaaaa
    26941 tattcccaac tactattatg acaatttaat tgataccatt gcccaatatg agaaaatggg
    27001 cttggaaaat ccttttatca tcattgatac caatcatgac aattctggta agcagtatat
    27061 tgaacagatc cgaattgtcc gccagacctt gattaaccgt gcttggaatg aaaaaattaa
    27121 gcagttcgtt cgtggtttta tgattgagtc ttatctggaa gatggtcgac aaaatgagcc
    27181 agaagtattt ggcaagtcta tcacagaccc ttgcctgggt tgggataaca cagaagctct
    27241 tgtcagagaa atttacaaaa cgttaggaga ataagatggc atttattgaa aaaggtcaag
    27301 aaatcgatat ggaagtcatc aaggctgaaa cccaattgtc tgcggaagcc ttgagactca
    27361 aggaaagccg tgacagggaa ttggcagata ttatttcagg ggaagatgac cgtattctct
    27421 tggtgattgg tccttgctct tctgataatg aagaggcggt cttggaatat gctcgccgtt
    27481 tatccgcctt gcaaaagaag gtagcggaca agattttcat ggtcatgcgc gtgtatactg
    27541 ctaagcctcg taccaatgga gacggctata aaggattggt tcaccagcca gatacttcta
    27601 aggctccaag cctgattaac ggtttgcagg ctgtgcgcca gttgcattac cgcgtgatta
    27661 cagagactgg tttgacaacg gcagatgaga tgctttatcc gtcaaatctg atcttggtgg
    27721 atgacttggt cagctaccat gccgttggag ctcgttctgt ggaagaccaa gagcaccgct
    27781 ttgtggcttc tgggattgat gcaccagtag ggatgaaaaa tccaacctca ggaaatttgg
    27841 gtgttatgtt taacgccatc tatgctgctc aaaacaagca aaccttcctt tatcatgggc
    27901 aggaagttga gacatcaggt aatcctttgg cccatgttat cctccgtgga gcagtcaacg
    27961 agtatggcaa ttatatgccg aattactact atgaaaacct actccaagcc attgaacgct
    28021 atgaaaccat gggacttgaa aatcctttta tcctcattga caccaaccat gataactcag
    28081 gcaagcaata tatggagcag attcgaattg ttcgccagac cttgcagaat cgtgattgga
    28141 atgagaaaat taaaaagacg gttcgaggat ttatgattga atcttaccta gcagatggtc
    28201 gtcaaaacca accagagatc tttggttgct ctattactga cccttgccta ggttgggaaa
    28261 atacagaggc cttggtagaa gagatttatg ttaccttgac aaaataagtg aaaaggatgg
    28321 agttggggaa tctcaactcc ttttgatgag aatgatagtt ggacacggaa ttgacatcga
    28381 agaattggct tcgatagaaa gcgcagttac acgacatgaa ggatttgcta agcgtgtact
    28441 gaccgctcag gaaatggagc gcttcaccag tctcaaagga cgcaggcaaa tagaatattt
    28501 agctggtcgc tggtcggcta aggaggcctt ttccaaggct atgggaacgg gcattagcaa
    28561 gctcggtttt caggatttgg aagtattgaa caatgaacgt ggggcgcctt attttagtca
    28621 ggcaccattt tcaggaaaga tttggctgtc tatcagccac accgatcagt ttgtgacagc
    28681 cagtgtcatt ttggaggaaa atcatgaaag ctagtccaca tagaccaacc aaggctctga
    28741 ttcatctggg agctattcga caaaatattc agcaaatggg ggctcatatc cctcaaggaa
    28801 cgctcaagtt ggctgtggtt aaggccaatg cttatggtca tggagctgtt gccgttgcca
    28861 aggcaattca agatgatgtt gatggctttt gcgtttccaa tatcgatgaa gccattgaac
    28921 tcagacaagc tggactcagc aagccaatcc tcattttagg agtttctgaa atcgaagctg
    28981 ttgctctagc taaagaatat gacttcacct tgacagtggc tggactggag tggattcaag
    29041 cactcttaga taaggaagtg gacctaactg gattgacagt ccacctcaag attgattcag
    29101 ggatgggacg gattggtttt agagaggcaa gtgaggttga gcaggctcaa gatttgctcc
    29161 aacaacacgg tgttcgtgtt gaaggaatct ttacccactt tgctactgct gatgaggaat
    29221 cagatgacta ttttaatgcc cagttagaac ggtttaaaac tattttagct agtatgaagg
    29281 aagttccaga gctggttcat gctagcaatt ctgcaacgac tctttggcat gtagagacta
    29341 ttttcaatgc ggttcgtatg ggagatgcca tgtatggtct caatccaagt ggagcggtct
    29401 tggctttgcc ttatgatttg ataccggcct tgaccttgga gtctgctctg gttcatatca
    29461 agacagttcc agctggtgct tgcatgggct atggagcaac ttatcaaacg gatagcgagc
    29521 aagtcatcgc gaccgtgcca atcgggtatg cagatggatg gacaagagac atgcaaaatt
    29581 tctctgtctt ggtagatggc caagcttgcc caattgtcgg cagggtttcg atggaccaaa
    29641 tcactattcg attgcctaag ccttacccac tcggaaccaa ggtaaccttg attggctcca
    29701 atggggataa ggaaatcact gcaactcagg tagcgaccta ccgcgtaacc attaactatg
    29761 aggtggtttg cctcctcagc gaccgtattc cgagagaata ttactagaaa agaaaggagt
    29821 ggagcatgaa tctacatcaa cccttgcatg tcttgcctgg tgtgggacca aagtcagcag
    29881 aaaaatacgc caaactagga attgaaaact tgcaagatct cttgctctac tttcctttcc
    29941 gttatgaaga cttcaaaatc aagcaggtgc tggagctgga agacggtgag aaggcagttc
    30001 tttctggtca ggtagtgact cctgctagtg tccagtatta tggtttcaag cgcaatcgcc
    30061 tgcgttttag tctcaagcag ggagaggtcg tttttgcggt gaatttcttt aaccagccct
    30121 atctggctga taaaatagag ttgggagcaa cccttgctgt ctttggaaaa tgggaccgcg
    30181 ctaaggctag tctgactggg atgaaggttc tggctcaggt agaagatgac ctccagcctg
    30241 tctatcgtct ggctcaggga atcagtcagg ccagtctggt taaggtcatc aagacggctt
    30301 ttgatcaggg actggacctc ttgatagaag aaaatctgcc ccagtcttta ctagacaaat
    30361 acaaactcat gtcccgttgt caggcagtcc gagctatgca ttttccaaag gatttggcag
    30421 aatacaagca ggctcttcgc cgtatcaagt ttgaggaact cttttatttc caaatgcagc
    30481 tgcagatgct caagtctgaa aatagagttc agggaagtgg tctggttctg aattggtctc
    30541 aggaaaaagt gacagcagtt aaagtaagtc ttccttttgc cctgacccaa gctcaggaaa
    30601 agagtttgca ggaaatttta actgatatga agtccgacca ccacatgaat cgtctcctac
    30661 aaggggatgt ggggagtgga aaaacggtag tcgctggctt ggccatgttt gcggcagtga
    30721 cagcaggtta tcaggctgcc ctaatggtac caacagaaat cctcgcagag caacactttg
    30781 agagtttaca gaaccttttt cccaatttga aactggctct cttgacaggt tccttgaaag
    30841 ctgcagaaaa gagagaggtc ttggagacca ttgccaaggg tgaggctgat ttgattatcg
    30901 gaactcacgc tctgatacaa gatggggtgg agtatgctcg tcttggtttg attattatcg
    30961 atgagcagca ccgttttggt gtagggcaaa ggcgtatttt acgggaaaaa ggtgacaatc
    31021 cagatgtcct catgatgacg gcgactccca ttccacggac gcttgccatc acagcctttg
    31081 gagatatgga tgtttccatt atcgaccaga tgccagcagg tcggaagcct attgtgacgc
    31141 gctggatcaa acatgagcaa ctacctcagg tcttgacttg gttagagggg gaaattcaaa
    31201 aaggttccca agcctatgtc atctctcctt tgattgaaga atcagaagct ctagatttga
    31261 aaaatgccat tgccttatca gaggagttga cgactcattt tgcaggcaag gcagaggtgg
    31321 ctcttctaca tggtaggatg aagagtgacg aaaaagacca gatcatgcag gatttcaagg
    31381 agagaaagac ggatattctg gtttcgacga cggttattga ggttggggtc aacgttccca
    31441 atgcgactgt catgattatc atggatgccg atcgcttcgg tctcagtcaa cttcaccagc
    31501 ttagaggtcg tgtcggtcgg ggggacaagc agtcctacgc tgttctcgtt gccaatccca
    31561 agacggattc tgggaaagac cgcatgcgta tcatgacaga aacgaccaat ggatttgtcc
    31621 ttgcggagga agatttgaaa atgcgtggtt ctggtgagat ttttggaacc agacagtcag
    31681 gacttccaga gttccaagtg gctgatatta tcgaagattt tccgatttta gaagaagcaa
    31741 gaaaggttgc tagctacatt agttctatag aagcttggca agaagatcca gagtggcgca
    31801 tgattgccct tcatctggaa aagaaagaac atctggatta agctttctct aaggaaaact
    31861 taagctagtt tttaggtttg gctcttatac taaagtcatc aaaaagaaac gaggactctc
    31921 atatgacagt aacgattaaa gtaaattacc aaaccacttt ccaaaagaag gaagcaaaaa
    31981 actagtataa acagaagaga gagcgaaatg ctctttttcg tttctaaaac tactttcagc
    32041 ccatcatcct aaaagtaaag aatctaaatt cactttctat ttatccttct ttcttgcatt
    32101 gattacatag atatgctaca gttgtggtaa cgattacaaa ataaaaggag catgctatga
    32161 aaaatccagc tttgctagaa gaaattaaga cctatagagg aagggatgag gttccggaag
    32221 actttgatgc tttctgggat ggggaagtga aaaatgtttc cacgcttcca tcctaccact
    32281 tggaggaaag agatttccac attcctcaag tcaagtgcta tgagttaaca tttgaaggaa
    32341 gcaaggaagg aaaggtctat gcacgcattg ttcttccaaa gagtgaggag aaggttccac
    32401 taatcttcca ttttcatggt tatatgggac gtggctggga ctgggccgac atgctgggct
    32461 tcaccgtagc tggttacggt gttgtttcca tggatgtgcg gggccagtca ggttactcac
    32521 aagacggctt gcgttctcct ttaggaaata ccgtgaaggg gcatattatc cgtggtgcta
    32581 tggaaggtcg ggaccacctc ttttataagg atgtttatct ggatatttac cagttggtcg
    32641 aaattgttgc tagtctgtct caggttgatg agaagcgtct ttctagctat ggtgcctcac
    32701 aaggaggggc tctagctcta gttgcagcag cgctcaatcc tcgaattcag aaaacagttg
    32761 ccatttatcc cttcttgtca gacttcagac gggtgattga gattggtaat actagcgagg
    32821 cttacgacga acttttccgt tatttcaagt ttcacgaccc cttccatgaa acagaggagg
    32881 aaatcatggc gacccttgcc tatatcgatg tcaaaaatct tgcccatcgt atccaaggtg
    32941 aggttaagat gattacgggc ttggacgacg atgtttgcta tcccattacc cagtttgcga
    33001 tttataatcg tctgacctgc gataaaacct atcgcatcat gcctgagtat gctcacgaag
    33061 ccatgaatgt atttgtcaat gaccaagtct acaactggct ctgtggaagt gagattcctt
    33121 ttaaatatct aaaataagga gtcgactcta agcacaaaat cttaaaaatt acaaacacgc
    33181 atagtatcag gggattaaaa aaacttgata ctatgcgttt tatcatggaa atatagtaaa
    33241 atgaaacaag aataggacaa aacgatcagg acagtcaaat cgatttctaa caatgtttta
    33301 gaagcaaatg tgtactattc tagtttcaat ctattatatt tatagaattt tttgttgcta
    33361 gatttgtcaa attgcttaaa ataatttttt tcagaaagca aaagccgata cctatcgagt
    33421 agggtagttc ttgctatcgt caggcttgtc tgtaggtgtt aatacttttc aaaaatctct
    33481 ttaaaccacg tcagcttcgc cttgccgtat atatgttact gacttcgtca gttctatctg
    33541 ccacctcaaa acggtgtttt gagctgactt tgtcagtctt atctacaacc tcaaaacagt
    33601 gttttgagca tcatgcggct agcttcttag tttgctcttt gattttcatt gagtataaaa
    33661 acagatgagt ttctgttttc tttttatgga ctataaatgt tcagctgaaa ctactttcaa
    33721 ggacattatt atataaaaga attttttgaa actaaaatct actatattac actatattga
    33781 aagcgtttta aaaatgaggt ataataaatt tactaacgct tataaaaagt gatagaatct
    33841 atctttatgt atatttaaag atagattgct gtaaaaatag tagtagctat gcgaaataac
    33901 agatagagag aagggattga agcttagaaa aggggaataa tatgatattt aaggcattca
    33961 agacaaaaaa gcagagaaaa agacaagttg aactactttt gacagttttt ttcgacagtt
    34021 ttctgattga tttatttctt cacttatttg ggattgtccc ctttaagctg gataagattc
    34081 tgattgtgag cttgattata tttcccatta tttctacaag tatttatgct tatgaaaagc
    34141 tatttgaaaa agtgttcgat aaggattgag caggaagtat ggtataaata gcataagctg
    34201 atgtccatca tttgcttata aagagatatt ttagtttaat tgcagcggtg tcctggtaga
    34261 taaactagat tggcaggagt ctgattggag aaaggagagg ggaaaattgg caccaatttg
    34321 agatagtttg tttagttcat ttttgtcatt taaatgaact gtagtaaaag aaagttaata
    34381 aaagacaaac taagtgcatt ttctggagta aatgtcttat ttcagaaatc gggatataga
    34441 tatagagagg atcagtatga atcggagtgt tcaagaacgt aagtgtcgtt atagcattag
    34501 gaaactatcg gtaggagcgg tttctatgat tgtaggagca gtggtatttg gaacgtctcc
    34561 tgttttagct caagaagggg caagtgagca acctctggca aatgaaactc aactttcggg
    34621 ggagagctca accctaactg atacagaaaa gagccagcct tcttcagaga ctgaactttc
    34681 tggcaataag caagaacaag aaaggaaaga taagcaagaa gaaaaaattc caagagatta
    34741 ctatgcacga gatttggaaa atgtcgaaac agtgatagaa aaagaagatg ttgaaaccaa
    34801 tgcttcaaat ggtcagagag ttgatttatc aagtgaacta gataaactaa agaaacttga
    34861 aaacgcaaca gttcacatgg agtttaagcc agatgccaag gctccagcat tctataatct
    34921 cttttctgtg tcaagtgcta ctaaaaaaga tgagtacttc actatggcag tttacaataa
    34981 tactgctact ctagaggggc gtggttcgga tgggaaacag ttttacaata attacaacga
    35041 tgcaccctta aaagttaaac caggtcagtg gaattctgtg actttcacag ttgaaaaacc
    35101 gacagcagaa ttgccaaatg gtcgagttcg cctgtatgtt aatggtgttt tatctcgaac
    35161 aagtctgaaa tctggcaatt tcattaaaga tatgccagat gtaacgcatg tgcaaatcgg
    35221 agcaaccaag cgtgccaaca atacggtttg ggggtcaaat ctacagattc ggaatctcac
    35281 tgtgtataat cgtgctttaa caccagaaga ggtacaaaaa cgtagtcaac tttttaaacg
    35341 ctcagattta gaaaaaaaac tacctgaagg agcggcttta acagagaaaa cggacatatt
    35401 cgaaagcggg cgtaacggta aaccaaataa agatggaatc aagagttatc gtattccagc
    35461 acttctcaag acagataaag gaactttgat cgcaggtgca gatgaacgcc gtctccattc
    35521 gagtgactgg ggtgatatcg gtatggtcat cagacgtagt gaagataatg gtaaaacttg
    35581 gggtaaccga gtaaccatta ccaacttacg tgacaatcca aaagcttctg acccatcgat
    35641 cggttcacca gtgaatatcg atatggtgtt ggttcaagat cctgaaacca aacgaatctt
    35701 ttctatctat gacatgttcc cagaagggaa gggaatcttt ggaatgtctt cacaaaaaga
    35761 agaagcctac aaaaaaatcg atggaaaaac ctatcaaatc ctctatcgtg aaggagaaaa
    35821 gggagcttat accattcgag aaaatggtac tgtctataca ccagatggta aggcgacaga
    35881 ctatcgcgtt gttgtagatc ctgttaaacc agcctatagc gacaagggtg atctatacaa
    35941 gggtaaccaa ttactaggca atatctactt cacaacaaac aaaacttctc catttagaat
    36001 tgccaaggat agctatctat ggatgtccta cagtgatgac gacgggaaga catggtcagc
    36061 gcctcaagat attactccga tggtcaaagc cgattggatg aaattcttgg gtgtaggtcc
    36121 tggaacagga attgtacttc ggaatgggcc tcacaaggga cggattttga taccggttta
    36181 tacgactaat aatgtatctc acttaaatgg ctcgcaatct tctcgtgtca tctattcaga
    36241 tgatcatgga aaaacttggc atgctggaga agcggtcaac gataaccgtc aggtagacgg
    36301 tcaaaagatc cactcttcta cgatgaacaa tagacgtgcg caaaatacag aatcaacggt
    36361 ggtacaacta aacaatggag atgttaaact ctttatgcgt ggtttgactg gagatcttca
    36421 ggttgctaca agtaaagacg gaggagtgac ttgggagaag gatatcaaac gttatccaca
    36481 ggttaaagat gtctatgttc aaatgtctgc tatccatacg atgcataatg gaaaagaata
    36541 cattatcctc agcaatgcag gtggaccgaa tcgtgaaaat gggatggtcc acttggcacg
    36601 tgtcgaagaa aatggtgagt tgacttggct caaacacaat ccaattcaaa aaggagagtt
    36661 tgcctataat tcgctccaag aattaggaaa tggggagtat ggcatcttgt atgaacatac
    36721 tgaaaaagga caaaatgcct ataccctatc atttagaaaa tttaattggg aatttttgag
    36781 caaagatctg atttctccta ccgaagcgaa agtgaagcga actagagaga tgggcaaagg
    36841 agagatgggc aaaggagtta ttggcttgga gtttgactca gaagtattgg tcaacaaggc
    36901 tccaaccctt caattggcaa atggtaaaac agcgactttc ctaacccagt atgatagcaa
    36961 aaccttgttg tttgcagtag ataaggaaga tatcggacag gaaattattg gtatagctaa
    37021 aggaagcatc gaaagtatgc ataatcttcc tgtaaatcta gcaggtgcca gagttcctgg
    37081 cggagtaaat ggtagcaaag cagcggtgca tgaagttcca gaatttacag ggggagttaa
    37141 tggtacagag ccagctgttc atgaaatcgc agagtataag ggatctgatt cgcttgtaac
    37201 tcttactaca aaagaagatt atacttacaa agctcctctt gctcagcagg cacttcctga
    37261 aacaggaaac aaggagagtg acctcctagc ttcactagga ctaacagctt tcttccttgg
    37321 tctgtttacg ctagggaaaa agagagaaca ataagagaag aattctaaac atttgatttt
    37381 gtaaaaatag aaggagatag caggttttca agcctgctat ctttttttga tgacattcag
    37441 gctgatacga aatcataaga ggtctgaaac tactttcaga gtagtctgtt ctataaaata
    37501 tagtagattg aaataagatg tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa
    37561 aattttagca gtcaaggtgt actgttatag attcaatata ttatgtgact attaaccttc
    37621 tcttctccta aaattgactt tcttgttttc ttatcttgtc cactcgaaac aagtattgta
    37681 agaatttgat tatttttgaa agtactttta atatacttga tatagttaaa aaagatttga
    37741 aactaaattc caaattagaa aaagacttga aatactaaaa aaaaaaagta tactctaatt
    37801 gaaaacggta acaaaactaa tttagagaat gaaatataga gtatttctct cttaaaagtt
    37861 tttggtgaaa cgagatgtag aaaggagatt tagccaaaga gtctattagt gctagaataa
    37921 tagattagaa ttattttaga aaaacgaagt gagcagctta taaattcaag tccccaaata
    37981 gattcatact agtatctttt gcaaaaaata aagggcgact tccttcatga atatcaattt
    38041 catctataag gaaggtagct aattgaacta acttatttat tctgtttgtc gctagaaaaa
    38101 tcagacctcc ttgtgaagat tgaggagata ctgaatgaaa atcaaagaag aaactagcaa
    38161 gctagtagca gattgcccaa aacaccgcct tgaggttgta gataagactg acctatataa
    38221 tccaaggtga agcgactgtg gtttgaagag attttcaaag agtataggct agagagtagt
    38281 gtttttatgt ccttctagta gaaaatgcta gacagaagaa tggggaactt ggataggaaa
    38341 aatagattga gaaaggaggt tagaagagat gattattaca aaaattagcc atttaggaac
    38401 ttatgtggga gtaaatccac attttgcaac attaatagat tttctagaaa aaacaggact
    38461 agaaaattta acagaaggtt cgattgctat cgatggtaat cgattgtttg ggaattgctt
    38521 tacttatcta gcagatggtc aagcaggggc tttctttgaa acacaccaaa aatatttgga
    38581 tattcattta gttttggaaa acgaagaagc catggctgtt acatcgccgg aaaatgtaag
    38641 cgttacccaa gaatatgatg aagagaaaga tattgaatta tacacaggga aagtggaaca
    38701 gttggttcag ttgagagctg gcgaatgcct catcactttt ccagaagatt tacatcaacc
    38761 caaggttcgt ataaatgatg aacctgtgaa aaaagttgtc tttaaagttg cgatttctta
    38821 atgtagaaag agaagaacga tgaaaaaaat gagaaagttt ttatgtctag ctggaattgc
    38881 gctagcggct gttgccttgg tagcttgttc aggaaaaaaa gaagctacaa ctagtactga
    38941 accaccaaca gaattatctg gtgagattac aatgtggcac tcctttactc aaggaccccg
    39001 tttagaaagt attcaaaaat cagcagatgc tttcatgcaa aagcatccaa aaacgaaaat
    39061 caagattgaa acattttctt ggaatgactt ctatactaaa tggactacag gtttagcaaa
    39121 tggaaatgtg ccagatatca gtacagctct tcctaaccaa gtaatggaaa tggtcaactc
    39181 agatgctttg gttccgctaa atgattctat caagcgtatt ggacaagata aatttaacga
    39241 aactgcctta aatgaagcaa aaatcggaga tgattactac tctgttcctc tttattcaca
    39301 tgcacaagtc atgtgggtta gaacagattt gttaaaagaa cataatattg aggttcctaa
    39361 aacttgggat caactctatg aagcttctaa aaaattgaaa gaagctggag tttatggctt
    39421 gtctgttccg tttggaacaa atgacttaat ggcaacacgt ttcttgaact tctacgtacg
    39481 tagtggtgga ggaagcctct taacaaaaga tcttaaagca gacttgacaa gccaacttgc
    39541 tcaagatggt attaaatact gggttaaatt gtataaagaa atctcacctc aagattcttt
    39601 gaactttaat gtccttcaac aagctacctt gttctatcaa ggaaaaacag catttgactt
    39661 taactctggc ttccatatcg gaggaattaa tgccaacagt cctcaattga ttgattcgat
    39721 tgatgcttat cctattccaa aaatcaaaga gtctgataaa gaccaaggaa ttgaaacctc
    39781 aaacattcca atggttgttt ggaaaaattc aaaacatcca gaagttgcta aagcattctt
    39841 agaagcactt tataatgaag aagactacgt taaattcctt gattcaactc cagtaggtat
    39901 gttgccaact attaagggga ttagcgattc tgcagcctat aaagaaaatg aaactcgtaa
    39961 gaagtttaaa catgctgaag aagtaattac tgaagctgtt aaaaaaggta ctgctattgg
    40021 ttatgaaaat ggaccaagtg tacaagctgg tatgttgact aaccaacaca ttattgaaca
    40081 aatgttccaa gatatcatta caaatggaac agatcctatg aaagcagcaa aagaagcaga
    40141 aaaacaatta aacgatttat ttgaggctgt tcagtagatg taaaagacta gaaaataggt
    40201 gggctagtga gctgaaaagc tctagcccaa tcttgtaaaa gaagggagaa ggagaatggt
    40261 taaagaacgt aatttaactc gctggatatt tgttttgcca gctatgatta tcgtaggatt
    40321 actctttgtt tatccgtttt tctcgagtat tttttatagc tttaccaata agcatttgat
    40381 tatgcctaat tataaatttg ttggtttggc taactataaa gctgtgctat cagatcccaa
    40441 cttctttaat gcgttcttta attcaattaa gtggaccgtt ttctcattag ttggtcaagt
    40501 tttagtaggg tttgtattgg ctttagctct tcacagagta cgccacttca agaaattata
    40561 taggacctta ttgattgttc cttgggcatt tcctaccatc gttattgcct tttcttggca
    40621 gtggattcta aacggggttt atggctactt acctaatcta atcgtaaaat taggtttaat
    40681 ggaacataca cctgcatttt tgacagatag tacatgggca ttcctatgtt tggtgtttat
    40741 caacatttgg tttggagcac caatgattat ggttaatgtg ctttcagctt tgcaaacagt
    40801 accagaagaa caatttgagg ctgctaagat agatggtgct tcaagttggc aggtgttcaa
    40861 gtttatcgtc tttccacata ttaaagtggt tgtaggactt ctagttgttt tgagaactgt
    40921 atggatcttt aataactttg acattatcta cctcattact ggtggtggac cagccaatgc
    40981 tacaacgacg cttccaattt ttgcttacaa cctgggctgg ggaactaaat tgttgggtcg
    41041 tgcttcagca gttacagtat tgctctttat cttcttggtg gcgatttgct ttatctactt
    41101 tgctatcatc agtaagtggg aaaaggaggg tagaaaataa tgaagaagaa atccagtatt
    41161 tatttagata ttctctcaca tgtactttta gttggtgcga ccatcgttgc aattttccca
    41221 ttggtatgga ttatcatatc ttctgtcaaa gggaaagggg aattaactca gtatccaaca
    41281 cgattttggc ctgaacagtt tacattagat tatttcactc atgttatcaa cgatttgcac
    41341 ttcattgata acattcgaaa cagtttaatc attgccttgg ctacaaccct cattgcgatt
    41401 attatttctg ctatggcagc ctatggtatt gttcgattct ttcctaaatt gggagcaatc
    41461 atgtcgagac tactcgtcat tacctacatt ttcccaccaa ttttgttagc aattccctat
    41521 tcaattgcca ttgctaaagt tgggttaaca aatagtttat ttggcttgat gatggtttat
    41581 ctatctttta gtgttccata tgcagtttgg ctcttagttg gatttttcca aacagttcca
    41641 attggaattg aagaagcggc tagaattgat ggtgcaaata aatttgttac gttttataaa
    41701 gttgtgctac cgattgtagc accaggtatt gtagcaacag ctatttatac atttatcaat
    41761 gcttggaatg aattcctgta tgccttgatt ttgattaaca atacaggaaa gatgacagta
    41821 gcagtagccc ttcgttcact taatggttca gaaatactag actggggaga tatgatggca
    41881 gcgtctgtta ttgtagttct tccatcaatt attttcttct ctatcatcca aaataagatt
    41941 gcaagtggat tatcagaagg atctgtgaag tagacgaaag aaggaaaaaa atgaataaaa
    42001 gaggtcttta ttcaaaacta ggaatttctg ttgtaggcat tagtctttta atgggagtcc
    42061 ccactttgat tcatgcgaat gaattaaact atggtcaact gtccatatct cctatttttc
    42121 aaggaggctc atatcaactg aacaataaga gtatagatat cagccctttg ttattagata
    42181 aattgtctgg agagagtcag acagtagtaa tgaaatttaa agcagatgaa ccaaactctc
    42241 ttcaagcttt gtttggccta tctaatagta aagcaggctt taaaaataat tacttttcaa
    42301 ttttcatgag agattctggt gagataggtg tagaaataag agacgcccaa aagggaataa
    42361 attatttatt ttccagacca gcttcattat ggggaaaaca taaaggacag gcagttgaaa
    42421 atacactagt atttgtatct gattctaaag ataaaacata cacaatgtat gttaatggaa
    42481 tagaagtgtt ctctgaaaca gttgatacat ttttgccaat ttcaaatata aatggtatag
    42541 ataaggcaac actaggagct gttaatcgtg aaggcaagga acattacctc gcaaaaagaa
    42601 gtattgatga aatcagtcta tttaacaaag caattagtga tcaggaagtt tcaaatattc
    42661 ccttgtcaaa tccatttcag ttaattttcc aatcaggaga ttctactcaa gctaactatt
    42721 ttagaatacc gacactatat acattaagta gtggaagagt tctatcaagt attgatgcac
    42781 gttatggtgg gactcatgat tctaaaagta agattaatat tgccacttct tatagtgatg
    42841 ataatgggaa aacgtggagt gagccaattt ttgctatgaa gtttaatgac tatgaggagc
    42901 agttagttta ctggccacga gataataaat taaagaatag tcaaattagt ggaagtgctt
    42961 cattcataga ttcatccatt gttgaagata aaaaatctgg gaaaacgata ttactagctg
    43021 atgttatgcc tgcgggtatt ggaaataata atgcaaataa agccgactca ggttttaaag
    43081 aaataaatgg tcattattat ttaaaactaa agaagaatgg agataacgat ttccgttata
    43141 cagttagaga aaatggtgtc gtttatgatg aaacaactaa taaacctaca aattatacta
    43201 taaatgataa gtatgaagtt ttggagggag gaaagtcttt aacagtcgaa caatattcgg
    43261 ttgattttga tagtggctct ttaagagaaa ggcataatgg aaaacaggtt cctatgaatg
    43321 ttttctacaa agattcgtta tttaaagtga ctcctactaa ttatatagca atgacaacta
    43381 gtcagaatag agaagagagt tgggaacaat ttaagttgtt gcctccgttc ttaggagaaa
    43441 aacataatgg aacttacttg tgtcctggac aaggtttagc attaaaatca agtaacagat
    43501 tgatttttgc aacatatact agtggagaac taacctatct catttctgat gatagtggtc
    43561 aaacatggaa gaaatcctca gcttcaattc cgtttaaaaa tgcaacagca gaagcacaaa
    43621 tggttgaact gagagatggt gtgattagaa cattctttag aaccactaca ggtaagatag
    43681 cttatatgac tagtagagat tctggagaaa catggtcgga agtttcgtat attgatggaa
    43741 tccaacaaac ttcatatggc acacaagtat ctgcaattaa atactctcaa ttaattgatg
    43801 gaaaagaagc agtcattttg agtacaccaa attctagaag tggccgtaag ggaggtcaat
    43861 tagttgtcgg tttagtcaat aaagaagatg atagtattga ttggaaatac cactatgata
    43921 ttgatttgcc ttcgtatggt tatgcctatt ctgcgattac agaattgcca aatcatcaca
    43981 taggtgtact gtttgaaaaa tatgattcgt ggtcgagaaa tgaattgcat ttaagcaatg
    44041 tagttcagta tatagatttg gaaattaatg atttaacaaa ataaaggaga aaaacatggt
    44101 taaatacggt gttgttggag cagggtattt tggagctgaa ttggctcgct acatgcaaaa
    44161 gaatgatgga gcagagatta ctcttctcta tgatccagat aatgcagagg cgattgcaga
    44221 agaattggga gcaaaagtag caagttcctt agatgagttg gtttctagcg atgaagtaga
    44281 ttgtgttatc gtcgcaactc caaataatct tcataaggaa ccggttatta aggctgcaca
    44341 gcatggtaaa aatgttttct gtgaaaaacc aattgcgctt tcttatcaag attgtcgcga
    44401 gatggtagat gcgtgtaaag aaaacaatgt aacctttatg gcaggacata ttatgaattt
    44461 ctttaatggt gttcatcatg caaaagaact cattaatcaa ggagttatcg gagacgttct
    44521 atattgtcat acagctcgta atggttggga agaacaacaa ccgtcagtgt catggaaaaa
    44581 aattcgtgaa aaatcaggtg gtcacttgta tcaccacatc catgaattgg attgcgttca
    44641 attccttatg gggggcatgc ctgaaactgt aaccatgaca ggtggaaatg tggcccatga
    44701 aggtgaacat ttcggtgatg aagatgatat gatttttgtc aatatggaat tttctaataa
    44761 gcgttttgcc ttgttagaat ggggttcagc ttatcgttgg ggtgaacatt atgtcttaat
    44821 ccaaggaagc aaaggtgcca tccgcttaga cttattcaac tgtaaaggaa ctcttaagct
    44881 agatgggcaa gaaagctatt tcttgattca cgaatcgcaa gaagaagatg atgatcggac
    44941 tcgtatctat catagtacag agatggatgg agcaattgct tatggtaaac caggtaaacg
    45001 tactccatta tggctatcat ctgtcattga taaagaaatg cgctatctgc atgagattat
    45061 ggaaggagct ccagtatcag aagaatttgc aaaacttttg acaggtgaag ctgccctaga
    45121 agcaattgct actgcagatg cttgtaccca gtctatgttt gaagatcgca aagtaaaatt
    45181 gtcagaaatt gtaaaataaa ttttggtatt ctcctattta taggtcgact tgctcctctg
    45241 aaagtacttt tagaggagct gtttgacttt gctagttttt gaaactgaaa tctattatac
    45301 tacaaactat tgaaagcgtt ttaattttaa ggtataataa tctcatagaa ataaagaaaa
    45361 ggaggaaaga ggatgccaca gattagcaaa gaagccttga ttgagcaaat caaagatgga
    45421 atcatcgttt cttgtcaggc tcttcctcat gaaccgcttt atacagaagc gggaggggtg
    45481 attcccttgc tggtcaaagc ggctgagcaa ggtggagcag tcggtatccg agcaaacagt
    45541 gttcgcgata tcaaggaaat taaggaagtc actaaacttc caatcattgg gattatcaaa
    45601 cgtgattatc cacctcagga acccttcatc acggctacta tgaaagaagt tgatgaattg
    45661 gcagaactgg acatcgaggt gattgctctg gattgtacca agcgtgaacg ctacgatggt
    45721 ttggaaattc aagagttcat tcgtcaggtt aaggagaaat atcctaatca gcttttgatg
    45781 gctgatacta gtatcttcga agaagggcta gcagctgtag aagcaggaat tgactttgtc
    45841 ggaacaacct tatcaggcta cacatcctac agtccaaaag tagacggtcc agattttgaa
    45901 ttgattaaga aactctgtga tgccggtgta gatgtcattg cagaaggaaa aattcataca
    45961 ccagaacaag ccaaacaaat ccttgaatat ggagtgcgag gcatcgttgt tggtggcgcc
    46021 attactagac caaaagagat tacagaacgc ttcgttgcta gtcttaaata agatgtgagg
    46081 gggagtttta tgtttaaagt tttacaaaaa gttggaaaag cttttatgtt acctatagct
    46141 atacttcctg cagcaggtct acttttgggg attggtggtg cactttcaaa cccaaccacg
    46201 atagcaactt atccaatact agacaatagt atttttcaat caatattcca agtaatgagc
    46261 tctgcaggag aggttgtatt cagtaatttg tcactacttc tctgtgtggg attatgtatt
    46321 ggcttagcga aacgagataa aggaaccgct gcgttagcag gagtaactgg ttacttagtt
    46381 atgactgcaa cgatcaaagc tttagtaaaa ctttttatgg cagaaggatc tgcaattgat
    46441 actggagtta ttggagcatt agttgtcgga atagttgccg tatatttgca caaccgatat
    46501 aacaatattc aattaccttc cgctttagga ttctttggag gttcacgctt cgttcctatt
    46561 gttacatcgt tctcttctat cttgattggc tttgtcttct ttgttatttg gccacctttc
    46621 caacaacttc ttgtttctac aggtggatat atttctcagg cgggtccaat tggaactttt
    46681 ctatatggat ttttaatgag actttctgga gcagtaggct tacatcatat aatttaccct
    46741 atgttttggt atactgaact tggtggtgtt gaaactgttg caggacaaac agtggttgga
    46801 gctcaaaaaa tattttttgc tcaattagcc gatttggccc attctggatt atttacagaa
    46861 ggaacaaggt tttttgcagg tcgtttctca acaatgatgt tcggtttacc ggctgcctgt
    46921 ttagcgatgt accatagtgt tcctaaaaat cgtcgtaaaa aatacgcggg tttgtttttg
    46981 ggagttgctt taacatcttt tattaccggt attacagaac caattgaatt tatgtttcta
    47041 ttcgttagtc cggttctata tgttgttcac gcattccttg atggtgttag cttctttatt
    47101 gcagacgtct taaatatttc aataggaaac acattttcag gaggtgtaat cgatttcact
    47161 ttatttggaa ttttgcaggg gaacgctaag acgaattggg ttcttcagat tccatttgga
    47221 cttatttgga gtgttttgta ttatattatt tttagatggt tcattactca attcaacgtt
    47281 ctaacgccag ggcgaggaga agaagtagat tctaaagaaa tttctgaatc cgcagattca
    47341 acttcaaata ctgcagatta tttaaaacag gatagcctac aaattatcag agccttgggt
    47401 ggatcaaata atatagaaga tgtagatgct tgtgtgacac gtttacgtgt agctgtaaaa
    47461 gaagttaatc aagttgataa agcactttta aaacaaattg gtgcagttga tgtcttagaa
    47521 gtgaagggtg gcattcaagc aatatatgga gcaaaagcaa tcttatataa aaatagtatt
    47581 aatgaaattt taggtgtaga tgattaagta cttactgact taataaaaaa cagaggagag
    47641 tgatggatga gtaggatgaa atgaaatcgc atacaagaaa taaagaactc attatccaag
    47701 ttggatacgc ttattacata ggagaataca aatgaaattt agaaaattag cttgtacagt
    47761 acttgcgggt gctgcggttc ttggtcttgc tgcttgtggc aattctggcg gaagtaaaga
    47821 tgctgccaaa tcaggtggtg acggtgccaa aacagaaatc acttggtggg cattcccagt
    47881 atttacccaa gaaaaaactg gtgacggtgt tggaacttat gaaaaatcaa tcatcgaagc
    47941 gtttgaaaaa gcaaacccag atataaaagt gaaattggaa accatcgact tcaagtcagg
    48001 tcctgaaaaa atcacaacag ccatcgaagc aggaacagct ccagacgtac tctttgatgc
    48061 accaggacgt atcatccaat acggtaaaaa cggtaaattg gctgagttga acgacctctt
    48121 cacagatgaa tttgttaaag atgtcaacaa tgaaaacatc gtacaagcaa gtaaagctgg
    48181 agacaaggct tatatgtatc cgattagttc tgccccattc tacatggcaa tgaacaagaa
    48241 aatgttagaa gatgctggag tagcaaacct tgtaaaagaa ggttggacaa ctgatgattt
    48301 tgaaaaagta ttgaaagcac ttaaagacaa gggttacaca ccaggttcat tgttcagttc
    48361 tggtcaaggg ggagaccaag gaacacgtgc ctttatctct aacctttata gcggttctgt
    48421 aacagatgaa aaagttagca aatatacaac tgatgatcct aaattcgtca aaggtcttga
    48481 aaaagcaact agctggatta aagacaattt gatcaataat ggttcacaat ttgacggtgg
    48541 ggcagatatc caaaactttg ccaacggtca aacatcttac acaatccttt gggcaccagc
    48601 tcaaaatggt atccaagcta aacttttaga agcaagtaag gtagaagtgg tagaagtacc
    48661 attcccatca gacgaaggta agccagctct tgaatacctt gtaaacggat ttgcagtatt
    48721 caacaataaa gacgacaaga aagtcgctgc atctaagaaa ttcatccagt ttatcgcaga
    48781 tgacaaagag tggggaccta aagacgtagt tcgtacaggt gctttcccag tccgtacttc
    48841 atttggaaaa ctttatgaag acaaacgcat ggaaacaatc agcggctgga ctcaatacta
    48901 ctcaccatac tacaacacta ttgatggttt tgctgaaatg agaacacttt ggttcccaat
    48961 gttgcaatct gtatcaaatg gtgacgaaaa accagcggat gctttgaaag ccttcactga
    49021 aaaagcaaac gaaacaatca aaaaagctat gaaacaatag tccttagtta ttctataaaa
    49081 agtagttttt taaagaacct aagagtgtat accccctttt ccctctacac agatagtgta
    49141 agaaaagggg gcttttgttt aaaatgtaag aaactgtcac gaaattaaaa tgaagttctt
    49201 acataagcga atcataaaaa atttcatttt gattttaaaa cagttcaaga aagtcaaaaa
    49261 attattctat ttgaaagaga ggtgccgact gtgaaagtca ataaaatccg tatgcgggaa
    49321 acagtgattt cctacgcttt cctagcacca gtattattct tctttgtcat ctttgtgttg
    49381 gctccgatgg tgatgggctt cattacaagt ttctttaact actcaatgac taaatttgag
    49441 tttgtaggct tggataacta tatccgtatg tttaaagatc ctgtctttac aaaatctctg
    49501 attaacacag ttattttggt tattggatct gtaccagttg ttgttctatt ctcactcttt
    49561 gtagcatctc agacctatca tcaaaatgtc attgccagat ccttctaccg tttcgtcttc
    49621 ttccttcctg ttgtaacggg tagtgttgcc gtgacagttg tttggaaatg gatttatgac
    49681 ccactatcag ggattctaaa ctttgtcctt aagtccagcc acatcatcag ccaaaacatt
    49741 tcttggttgg gagataaaaa ctgggcattg atggcgatta tgattattct cttgaccact
    49801 tcagttggtc agcccatcat cctttatatc gctgccatgg ggaatattga caattcactg
    49861 gttgaagcgg cgcgtgttga tggtgcaact gagtttcaag ttttttggaa gattaaatgg
    49921 ccaagccttc ttccaacaac tctttatatt gcaatcatca caacaattaa ctcattccag
    49981 tgtttcgcct tgattcagct tttgacatct ggtggtccaa actactcaac aagtaccttg
    50041 atgtactacc tttacgaaaa agccttccaa ttgacagaat acggctatgc caacacaatt
    50101 ggtgtcttct tggcagtcat gattgctatc gtaagctttg ttcaatttaa agtacttgga
    50161 aacgacgtag aatactaaag aaaggagaca gctatgcaat ctacagaaaa aaaaccatta
    50221 acagccttta ctgttatttc aacaatcatt ttgctcttgt tgactgtgct gttcatcttt
    50281 ccattctact ggattttgac aggggcattc aaatcacaac ctgatacaat tgttattcct
    50341 cctcagtggt tccctaaaat gccaaccatg gaaaacttcc aacaactcat ggtgcagaac
    50401 cctgccttgc aatggatgtg gaactcagta tttatctcat tggtaaccat gttcttagtt
    50461 tgtgcaacct catctctagc aggttatgta ttggctaaaa aacgtttcta tggtcaacgc
    50521 attctatttg ctatctttat cgctgctatg gcgcttccaa aacaagttgt ccttgtacca
    50581 ttggtacgta tcgtcaactt catgggaatc cacgatactc tctgggcagt tatcttgcct
    50641 ttgattggat ggccattcgg tgtcttcctc atgaaacaat ttagtgaaaa tattcctaca
    50701 gagttgcttg aatcagctaa aatcgacggt tgtggtgaga ttcgtacctt ctggagtgta
    50761 gccttcccga ttgtgaaacc agggtttgca gcccttgcaa tctttacctt catcaatact
    50821 tggaatgact acttcatgca gttggtaatg ttgacttcac gtaacaattt gaccatctca
    50881 cttggggttg cgaccatgca ggctgaaatg gcaaccaact atggtttgat tatggcagga
    50941 gctgcccttg ctgctgttcc aatcgtcaca gtcttccttg tcttccaaaa atccttcaca
    51001 cagggtatta ctatgggagc ggtcaaagga taatactctg cgaaaatcga atgcaaacta
    51061 cgtcagcttc accttgccat acttaagtat tgcctgcggt tagcttccta gtttgttctt
    51121 caattttcat tgagtatagg aaaatcaatc tatcaagata cagaagtata ttttatagat
    51181 ttagagaata tagaagttat aagtgtctac aaaatggagg gtatgcagtt actttatgaa
    51241 gttttgtcag acacttatca acttaagaat gattttagtt aattatcaga aacgaaggaa
    51301 agagtatgat ttttgacgat ttgaaaaaca tcacctttta caaagggatt catcccaatt
    51361 tagacaaagc tatcgactac ctctaccaac atcgtaaaga ttcattcgaa ttaggaaagt
    51421 atgagattga tggagataag gtctttctag ttgttcagga aaatgtcctc aatcaagttg
    51481 agaataatca atttgaacac cataagaact atgcagattt gcatttgctg atagaagggc
    51541 atgaatattc gagctacggt tcacgtatca aagacgaggc agtagcattc gacgaagcga
    51601 ctgacattgg ctttgttcat tgtcatgaac actacccact cttgttgggt tatcataatt
    51661 ttgcgatttt cttcccaggt gagccacatc agccaactgg ctatgcaggt atggaagaaa
    51721 aggttcgaaa atatctcttt aaaattttga ttgattaaaa ataggatgaa ttgttttttt
    51781 gtaaagcttt gacaatactc taccatgaaa ttgatcttta tgaggtagag aaatgagaat
    51841 aaaatattta aaaattggta tcttctaagc atgctgcaag agctagtttc ttagatggac
    51901 aggaaattac agttgatgag atgtcctgga taattaatgg cattgtgaat gcattgattg
    51961 gtagatacat aaaattaggt acttatgcag ctaagtatgg tattggtata gcacgctcga
    52021 tcttaagtag ggcagctgca actgcagcag caagagtagg attactgacc aagatttctg
    52081 gatggatttt acgagtagct gtgaatgtag ctgatgtata tggtaatttc gccaacaata
    52141 ttgctgcagc ttgggatgca tatgataaaa ttcctaacaa tggtcgtata aacttttaaa
    52201 atacgagaat gaaagcactt tgtatttttt tattgaatat gttagcttgg acagtgcttg
    52261 caatgataat tcgtggaggg ctagatggat ttgataggca tacttggagt actattttaa
    52321 ttgcttcgct gttcggggta tatgattata agcccataga taaaaataga aaaaagtcca
    52381 aaagaaaaaa gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa
    52441 aaaagaaaac agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta
    52501 agccttatca aggcagcatt tgatacagat aactttctca tgcgttttag tgagaaggtc
    52561 ttggacatcg tgacagccaa tcttcttttt gtcgtctctt gtttacccat cgtgacgatt
    52621 ggagtggcta aaatcagcct ctacgagacc atgttcgaag ttaagaagag cagacgggtg
    52681 cctgttttta aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg
    52741 ggtttaatgg agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt
    52801 caaacagctc tgcccttcca attgctgaaa gccatttgtt taggtattct gatttttctt
    52861 actatcgtga tgctggctag ttaccctatc gcggcacgtt atgacctatc ttggaaagaa
    52921 attcttcaaa aaggattgat gttggctagt tttaactttc cttggttctt cctcatgtta
    52981 gccattcttg tcctcattgt gatggttctt tatctgtccg ccttcagtct actcttaggt
    53041 ggctcagtct tcctactttt tgggtttgga ctattggtct ttatccagac tggattgatg
    53101 gagaaaattt tcgcaaaata ccaataggag ctttatttct gaaactactt tcaaaggctc
    53161 caaacgctat tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct
    53221 tttcggtaaa gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat
    53281 aataggagaa aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac
    53341 gcatgttatg atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt ggttcaatac
    53401 ttcattgata aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac
    53461 caaagcgttg aagatcgcaa gttgattttg gaagaagtca tggcggtagc taaaggtaaa
    53521 ttgaccatta ttgcccatgt tgcctgcaac aatactaaag acagtatgga acttgctcgc
    53581 catgctgaaa gcttgggagt agatgctatt gcaacgattc caccaattta tttccgcttg
    53641 ccagaatact cagttgccaa atactggaac gatatcagtt ctgcagctcc aaacacagac
    53701 tacgtgattt acaacattcc tcaattggca ggggttgctt tgactccaag cctttacaca
    53761 gaaatgttga aaaatcctcg tgttatcggt gtgaagaact cttctatgcc agttcaagat
    53821 atccaaacct ttgtcagcct tggtggggaa gaccatatcg tctttaacgg tccagatgaa
    53881 cagttcctag gtggtcgcct catgggtgcc aaagctggta tcggtggtac ttatggtgct
    53941 atgccagaac tcttcttgaa actcaaccaa ttgattgcgg ataaagattt agaaacagcg
    54001 cgtgagttac agtatgctat caacgctatc attggtaaat tgactgctac acatggaaat
    54061 atgtacggtg tcatcaaaga agttttgaag atcaatgaag gcttgaatat tggttctgtt
    54121 cgttcaccat tgacaccagt gactgaagaa gatcgtccag ttgtagaagc ggctgctgcc
    54181 ttgattcgtg aaaccaagga gagcttcctc taatctaaaa ggaggtattt atgacatact
    54241 acgttgcaat tgatatcggt ggaaccaaca tcaagtatgg tttggttgat caagaggggc
    54301 aacttcttga atcgcatgaa atgccaactg aggcgcataa gggtggacct catatcttac
    54361 aaaagaccaa agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca
    54421 tatcttctgc tgggatggtg gatccggata agggtgagat tttctatgct gggccgcaaa
    54481 tccctaacta cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt
    54541 gtgagattga aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca
    54601 agggagcaag tgtgacactt tgcttgacca ttggaaccgg tatcggtggt tgcttgatta
    54661 tggataggaa agtcttccat ggttttagca attcagcctg tgaagtcggg tatatgcata
    54721 tgcaggatgg agcttttcaa gacttggctt ctacaacagc tttagtgaaa tatgtagctg
    54781 aagcccatgg agaagatgtt gatcagtgga atggccgtag aattttcaaa gaagccactg
    54841 aaggaaacaa aatctgcatg gaaggtattg accgtatggt tgactatcta ggaaaaggtc
    54901 tggcaaatat ttgctacgtt gccaatccag aagtggttat tcttggtggt ggtatcatgg
    54961 ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt gaaagaggct ttggtaccaa
    55021 gtttagcaga aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg
    55081 gtgcatatta tcattttaag acaaaacaat cctagtttgg ctcagccaaa ctaggatttt
    55141 cttacacgtt tttgtctacg atagccgttg agttttttat tttcccagta gctattaaag
    55201 attttttcct tgctttcgcg attgatttcc aaaaagtagg cataaatcaa atcgataaag
    55261 aagagcatag gaagttgagc ggatattcgt tggatatagg agggttggct gtgggtggct
    55321 acaagaacag tctctgtata ggtctggcta tctttattgg gaacacttgt aaagagtaca
    55381 gtctttgccc ccatctcctt ggcatctaat agactatcta aaatagaagg agttgagcct
    55441 gaaagtgaga agcccagtac tagacaattt tcatccatga tgctggttgt ccaggcaaag
    55501 ccgtcttggt ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg taatttcatt
    55561 tcacgggcga cgaggccaga actccctgtt ccaaagaagt agatacgctc agcatcttcg
    55621 attagctggg caattcgctc tagttggatt tcgtcaatca agtcttgtgt ttgttccctc
    55681 atattgctat aacttctgag gactcgtttg gtcagtggac tgtgcttgga gactcggttg
    55741 gcttgatttt ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc agtaaagcca
    55801 cactttttag caaagcgggt caaagcagct tgagaaatat gtaatttttg ggtgacttgt
    55861 tgagaagata aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc gatttcttgc
    55921 tctaggtctg tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc tggtttgtcc
    55981 atagggaaag ctcctttaca tgagtcatac tggaagacta gatcagggaa tagtcacact
    56041 tcattataac acataatata aggatagata aataaaaacg catctctgtt ttaaaaacga
    56101 aaaaatcgaa aaagcttctc tcttttccat aattttctac tcaaattgtg gtacaattaa
    56161 gagtaagatt ttaagttaga aatgagactg atttgtatga gaaaatttaa cagccattcg
    56221 attccgattc ggcttaattt attgttttca atcgtcattt tactctttat gaccattatt
    56281 ggtcgtttgt tgtatatgca ggttttgaac aaggattttt acgaaaaaaa gctagcctca
    56341 gctagtcaga ccaagattac aagcagttca gcccgtgggg aaatttatga tgctagtgga
    56401 aaacctttgg tagaaaatac gttaaagcag gttgtttcct ttacgcgtag caataaaatg
    56461 acggctacag acttaaaaga aacagctaaa aagttactga cttatgtgag catcagttct
    56521 ccaaatttga caaaacgcca gctggcggat tactatttgg ctgatcctga aatctataaa
    56581 aaaacagtgg aagctctccc aagcgagaaa cgcttggatt cagatggcaa tcgtctatcc
    56641 gaatcagaac tgtataacaa tgcggtcgat agtgtccaaa caagtcaact aaactataca
    56701 gaggatgaaa agaaagaaat ctatcttttt agtcagttaa atgctgttgg aaactttgcg
    56761 acaggaacca ttgctacaga tcctctaaat gattctcagg tggctgttat tgcctctatt
    56821 tcaaaggaga tgcctggcat tagtatttct acttcttggg atagaaaggt tttggaaact
    56881 tccctttctt ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc agcggaagaa
    56941 gcagaagcct atcttaaaaa aggctattct ctaaatgacc gtgtaggaac ctcctatttg
    57001 gaaaagcaat atgaagagac cttacaagga aaacgatcgg taaaagaaat ccatctggat
    57061 aaatatggca atatggaaag cgtggataca attgaggaag gtagtaaggg aaacaatatc
    57121 aaactgacca ttgatttggc cttccaagat agcgtggatg ctttgctgaa aagttatttc
    57181 aattctgagc tagaaaatgg tggagccaag tattctgaag gtgtctatgc agtcgccctt
    57241 aacccaaaaa caggtgcggt tttgtctatg tcagggatta aacatgactt gaaaacggga
    57301 gagttgacgc ctgattcctt gggaacggta accaatgtct ttgttccagg ttcggttgtc
    57361 aaggcggcga ccatcagctc aggttgggaa aatggagtct tgtcaggaaa ccagaccttg
    57421 acagaccagt ccattgtctt ccaaggttca gctcccatca attcttggta tactcaggct
    57481 tacggttcat tccctatcac agcggtccaa gctctggagt attcatcaaa tacctatatg
    57541 gtccaaacag ccttaggtct tatggggcaa acctatcaac ccaatatgtt tgtcggcacc
    57601 agcaatctag agtctgctat ggagaaactg cgttcaacct ttggcgaata tggcttgggt
    57661 actgcgacag gaattgacct accagatgaa tctactggat ttgttcccaa agagtatagc
    57721 tttgctaatt acattactaa tgcctttggg cagtttgata actatacgcc gatgcagttg
    57781 gctcagtatg tagcaactat tgcaaataat ggtgttcgtg tggctcctcg tattgttgaa
    57841 ggcatttatg gtaataatga taagggagga ctgggtgact tgattcagca actgcaaccg
    57901 acagagataa ataaggtcaa tatatccgac tccgatatga gcatcttgca ccaaggtttt
    57961 tatcaggttg cccatggtac tagtggattg acaactggac gtgccttttc aaatggtgcc
    58021 ttggtatcca ttagcggaaa aacaggtaca gccgaaagct atgtggcaga tggtcagcaa
    58081 gcaaccaata ccaatgcggt ggcctatgcc ccatctgata atccccaaat cgctgtcgca
    58141 gtggtctttc ctcataatac caatctaaca aatggtgtag gaccttccat tgcgcgtgac
    58201 attatcaatc tgtatcaaaa ataccatcca atgaactaga aaggaaatta tgctttatcc
    58261 aacacctatt gccaagttga ttgacagtta ttctaagtta ccaggtatcg ggattaagac
    58321 ggctacgcgt ctggcctttt atacgattgg gatgtctgct gatgatgtca atgaatttgc
    58381 aaaaaatctc ctttctgcta agagagaatt gacatattgt tctatttgtg gacgtttgac
    58441 agacgacgat ccttgttcta tctgtactga tccgactcgt gaccagacaa caattttagt
    58501 tcttgaggat agtagagatg tggcagccat ggaaaatatc caagaatacc atggactcta
    58561 tcatgtcctg catggcctca tttctcctat gaatggtatc agtccggacg atatcaatct
    58621 caagagcctt atgactcgtc ttatggatag tgaggtttca gaagtgattg tggcgactaa
    58681 tgctacagcg gatggtgaag cgacttccat gtatctttca cgtttgctca agccagctgg
    58741 tatcaaggtt acgcgtctag cacgaggtct cgctgtggga gcggacattg agtatgcgga
    58801 cgaagtgaca ctcttacgag cgattgaaaa tcggacagag ttgtaagtgt aggcaaattt
    58861 acgaactccc ttcatttata aaaaatcaaa gaggctgaaa atcgttccta tcggcctctt
    58921 tttgtatagt gtgatgagta ggatcgggtt caagttttaa aaaaccaagc aaatatgata
    58981 tactaaagag cgagtattct agtagaatta ggacaaataa tatgaaacaa acgattattc
    59041 ttttatatgg tggacggagt gcggaacgcg aagtctctgt cctttcagct gagagtgtca
    59101 tgcgtgcggt caattacgac cgtttcacag tcaagacttt ctttatcagt cagtcaggtg
    59161 actttatcaa aacacaggaa tttagtcatg ctccggggca agaagaccgt ctcatgacca
    59221 atgaaaccat tgattgggat aagaaagttg caccaagtgc tatctacgaa gaaggtgcag
    59281 tggtctttcc agtccttcac gggccaatgg gagaagatgg ctctgttcaa ggattcttgg
    59341 aagttttgaa aatgccttac gttggttgca acattttgtc atcaagtctt gccatggata
    59401 aaatcacgac taagcgtgtt ctggaatctg ctggtattgc ccaagttcct tatgtggcta
    59461 tcgttgaagg cgatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa ttggcttatc
    59521 cagtcttcac taagccgtca aacatggggt ctagtgtcgg tatttctaag tctgaaaacc
    59581 aagaagaact ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt gtcttggttg
    59641 agcaaggagt gaatgcccgt gaaattgagg ttggcctctt gggtaactac gatgtcaaga
    59701 gcacgctacc tggagaagtt gtcaaggacg ttgcctttta tgactacgat gccaagtata
    59761 ttgataacaa gattactatg gatattcctg ccaaaatcag tgatgatgtg gtagctgtca
    59821 tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg ccttggtcta tctcgttgcg
    59881 atttcttcta tacagataag ggagagattt ttctcaacga gctcaatacc atgccaggtt
    59941 tcacccagtg gtctatgtac ccactacttt gggacaatat ggggatcagc tacccagaac
    60001 taatcgagcg tttggttgac cttgccaagg aaagttttga caagcgcgaa gcgcatttga
    60061 tataaaatga aagagagggt agaagccaga accatcactg caaggtgact agagttctcg
    60121 gacttcagcc ctttttaaag gagtagaaat gaaattaaca atccatgaag ttgcccaagt
    60181 tgttggagcc aaaaatgata tcagtatctt tgaggacacc cagttagaaa aagctgagtt
    60241 tgatagtcgt ttgattggaa ctggagattt atttgtgccc ctaaaaggtg tgcgtgacgg
    60301 tcatgacttt atcgaaagag cttttgaaaa tggtgcggca gcaaccctgt ctgagaaaga
    60361 ggttgcaaat catccctaca ttctagtaga tgatgttttg actgcctttc aacaactagc
    60421 tgcctactat cttgaaaaaa cagctgttga tgtctttgcg gttacgggtt caaatggcaa
    60481 gacaacgact aaggatatgt tggcgcattt actgtcaaca agatacaaga cctacaaaac
    60541 acaaggcaat tacaataatg agattggcct tccttacaca gttctccaca tgcctgaagg
    60601 aacagaaaag ttggtcttgg agatggggca ggaccacttg ggagatattc atctcttgtc
    60661 tgaattggct cgtccaaaaa cagccatcgt gaccttggtt ggagaagctc atttggcctt
    60721 tttcaaagat cgttctgaga ttgctaaagg aaaaatgcaa attgcagacg gaatggcttc
    60781 aggttccttg cttttagcgc cggctgaccc tatcgtagag gactatttgc caactgataa
    60841 aaaggtggtt cgttttggtc aaggagcaga gctggaaatt actgacttgg ttgagcgcaa
    60901 agatagtctg accttcaagg ccaatttctt agagcaagtc cttgatttgc cagtaactgg
    60961 caagtacaat gcgacaaatg ctatgattgc atcctatgtt gccttgcaag aaggagtttc
    61021 agaggagcaa attcgtttgg ccttccaaca tcttgaattg acgcgtaacc gtaccgagtg
    61081 gaagaaagca gccaatggag cagacatctt gtcagatgtt tacaatgcca atccaactgc
    61141 tatgaagctg attttagaga ccttctctgc cattccagcc aatgaaggtg gcaagaaaat
    61201 tgcagtgttg gcggatatga aggaacttgg tgtccagtct gttcaacttc ataatcagat
    61261 gattttgagc ctttcgccag atgtgcttga tactgttatt ttctacggag aagatattgc
    61321 tgaattagcc caacttgcta gtcaaatgtt cccaatcgga cacgtttatt acttcaagaa
    61381 aacagaagac caagaccaat ttgaagacct agttaagcag gtcaaagaaa gccttggggc
    61441 tcatgaccaa atcctgctca aaggctctaa ctctatgaat ctagccaagt tggtagaaag
    61501 tttagaaaat gaagacaagt gattttgtca agtatttgca aagaatgatt gccattacag
    61561 atactggatt aacctttaca aaagatccgt ttgaccgtga gcgctacgaa gacttgcgag
    61621 accttctatc tgaaatgttg aatcaagcat cagaccttga ttccgaagaa gtggcagaag
    61681 tcttgaagcc aacttctgct tatgcgactc ccttaatgga cgtccgtgct tggattgttg
    61741 aggacgaaaa gatttgtctg gttaggggac aaggagagga tagttgggct ttgccaggtg
    61801 gctttggtga agtcggctat tctccaactg aaaatattct caaggaaatt gaagaagaaa
    61861 ccggttttaa agccaaagtt gaaagactgc tagctgtttt tgataccaat cgtttccaac
    61921 tacagagcaa acaatatgca aagtttgttt ttgaatgtaa gcttctcgat ggacaattcc
    61981 aagaaaatca agaaatcgct gaccttcaat tttttgcaat tgacccactg ccgaatttat
    62041 ctgaaaaacg cattaccaag gagcaaatcg agattctttg gcaggtttat caaggtcaga
    62101 gggagcaata tcttgactaa gaagatgatt atcgtatttc taaattcatt tttcttaagt
    62161 agcatggtat aataaaatgc aggaaaattt tgaatcatga ggaagactag atgaatttat
    62221 gggatatttt ctttacgact caggcaaccg agccgcccaa atttgacctt ttttggtatg
    62281 ttagcctatt tacgctctta gccttaacct tttatacagc ccatcgctat cgtgaaaaga
    62341 aggtttacca acgatttttc caaatcttgc agactgttca gttaatcctt ctttatggtt
    62401 ggtactgggt caatcatatg ccactgtcag aaagcctacc cttttaccat tgccgtatgg
    62461 ctatgtttgt ggtactcttg cttcctggtc agtccaaata taaacaatac tttgcattat
    62521 tgggaacatt tgggacatta gcagcctttg tttatccagt gccagatgct tacccttttc
    62581 cacatatcac cattctatcc tttatctttg gtcatttagc actcttgggg aactctctag
    62641 tttatctatt gagacagtat aatgcgcgat tgctggatgt gaagggaatt tttctcatga
    62701 cctttgccct aaatgccttg atttttgtgg tcaatttggt gacaggtggc gattacggat
    62761 ttttgacaaa accgccattg gttggggatc acggtctagt agctaattat ttacttgttt
    62821 caattgtgct ggtagctact atcagtttga ctaagaaaat cttagaattc tttttagctc
    62881 aagaagcaga aaaaatgatt gcaaaggaag cttaacacag agctttcttt tttgctctta
    62941 gagagttttt acaagcagct tataaaataa gaatttctga atagacaaac tcaaaaaatg
    63001 gctgggaaat ttaggaaaaa agcaagcacg attaaatttt ttgtgttata atattttgtg
    63061 aatagctatg cctatgttta gctatggaat aatacgaagt gcgaaacttg gaagatagag
    63121 aggaagcgat gtaatggcta gagaaggctt ttttacaggt ctagatattg gaacaagctc
    63181 tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa
    63241 tgccaaaagt aaaggtgtaa aggatggaat tattgttgat attgatgcag cagcaactgc
    63301 tatcaagtca gccatttccc aagcggaaga aaaggcaggc atttcgatta aatcagtaaa
    63361 tgtcggcttg cctggtaatc ttttgcaggt agaaccaact caggggatga ttccagtaac
    63421 atctgatact aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat cagctttgac
    63481 aaagagtatg acacctgacc gtgaagtcat tacctttatt cctgaagaat ttattgtgga
    63541 tggtttccaa gggattcgtg acccacgtgg catgatgggg gttcgccttg aaatgcgtgg
    63601 tttgctttat acaggacctc gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc
    63661 aggtgttcag gttgaaaata ttatcatttc accactagca atggttcagt ctgttttgaa
    63721 tgaaggggaa cgtgaatttg gtgctacagt gattgatatg ggggcaggtc aaacgactgt
    63781 cgctacaatc cgtaatcaag aactccagtt cacacatatt ctccaagaag gtggagatta
    63841 tgtaactaaa gatatctcca aggttttgaa aacctctcgc aaattagcgg aaggcttgaa
    63901 actgaattac ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt
    63961 tattggagaa gtggaagcag tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc
    64021 acgaatcaag cacatccttg aacaaatcaa gcaagaatta gatagaaggc gtctattgga
    64081 cctccctggt ggtattgtct taatcggtgg gaatgccatt ttaccaggta tggttgagct
    64141 tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg
    64201 taatccagcc tttgcgcatg tgattagttt atcagaattt gcgggtcaat taacagaagt
    64261 taatcttttg gctcagggag cgataaaagg tgagaatgac ttaagtcatc agccaattag
    64321 ttttggtggg atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc
    64381 tcctgctcca gaagtagagt cggtggcgcc tacagaacca atggcggatt tccaacaagc
    64441 ttcacaaaat aaaccgaaat tagcagatcg tttccgtggc ttgatcggaa gcatgtttga
    64501 cgaataaaga ggaaaaataa attatgacat tttcatttga tacagctgct gctcaagggg
    64561 cagtgattaa agtaattggt gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg
    64621 acgaaggtgt tacaggcgta gaatttatcg cagcaaacac agatgtacaa gcattgagta
    64681 gtacaaaagc tgagactgtt attcagttgg gacctaaatt gactcgtggt ttgggtgcag
    64741 gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag
    64801 ctattagtgg tgccgatatg gtcttcatca ctgctggtat gggaggaggc tctggaactg
    64861 gagctgctcc tgttattgct cgtatcgcca aagatttagg tgcgcttaca gttggtgttg
    64921 taacacgtcc ctttggtttt gaaggaagta agcgtggaca atttgctgta gaaggaatca
    64981 atcaacttcg tgagcatgta gacactctat tgattatctc aaacaacaat ttgcttgaaa
    65041 ttgttgataa gaaaacaccg cttttggagg ctcttagcga agcggataac gttcttcgtc
    65101 aaggtgttca agggattacc gatttgatta ccaatccagg attgattaac cttgactttg
    65161 ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct tatgggtatt ggtatcggta
    65221 gtggagaaga acgtgtggta gaagcggcac gtaaggcaat ctattcacca cttcttgaaa
    65281 caactattga cggtgctgag gatgttatcg tcaacgttac tggtggtctt gacttaacct
    65341 tgattgaggc agaagaggct tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca
    65401 tctggctcgg tacttcaatt gatgaaagta tgcgtgatga aattcgtgta acagttgttg
    65461 caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct agatctgcta
    65521 ctaactaccg tgagacagtg aaaccagctc attcacatgg ctttgatcgt cattttgata
    65581 tggcagaaac agttgaattg ccaaaacaaa atccacgtcg tttggaacca actcaggcat
    65641 ctgcttttgg tgattgggat cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg
    65701 tttctccagt cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa ttggatacac
    65761 ctccattttt caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga acttgttttt
    65821 cgagaagttg cagaggctag tctgagtgct catcgagaga gtggttcggt ctctgtcatt
    65881 gcagttacca agtatgtaga tgtaccgaca gcggaagcct tgcttccgct aggtgttcat
    65941 catatcggtg aaaatcgtgt agataagttt ctggaaaaat atgaagcttt aaaagatcga
    66001 gatgtgactt ggcatttgat tggtaccttg caaagacgta aggtgaaaga tgtcattcaa
    66061 tacgttgatt atttccatgc attggactca gtaaagctag caggggaaat tcaaaaaaga
    66121 agtgaccgag tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga aagcaaacac
    66181 ggtttttcga gagaggaact gctggaaatc ttgccagagt tagccagact agataagatt
    66241 gaatatgttg gtttaatgac gatggcacct tttgaggcta gcagtgagca gttgaaagag
    66301 attttcaagg cgacccaaga tttacaaaga gaaattcaag agaaacaaat tccaaatatg
    66361 cctatgaccg agttaagtat gggaatgagt cgtgattata aagaagcgat tcaattcggt
    66421 tccacttttg ttcgtatagg tacatcattt tttaagtagg agagaaccat gtctttaaaa
    66481 gatagattcg atagatttat agattatttt acggaggatg aggattcaag tctcccttat
    66541 gaaaaaagag atgagcctgt gtttactcca gtaaattctt cacaggaacc ggctctccca
    66601 atgaatcaac cttcacagtc ggctggtaca aaagagaaca atatcaccag acttcatgca
    66661 agacaacagg aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt
    66721 cgttatccta gaaaatatga ggatgcaaca gaaattgttg atttattggc aggaaacgaa
    66781 agtatcttga ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg tttggactat
    66841 ttggatggag cttgtcatgt tttagctgga aatttgaaaa aggtagcttc taccatgtat
    66901 ttgttgacac cagtgaatgt tattgtaaat gttgaagata tccgtttacc agatgaagat
    66961 caacagggtg agttcggttt tgatatgaag cgaaatagag tacgataatg atttttttaa
    67021 ttcgtatgat ttataatgca gtggatattt actccctgat tttggtagcc ttcgctgtca
    67081 tgtcttggtt tccaggtgcc tacgaatcca gtttaggtcg ttggattgta gcgttggtga
    67141 aaccagtgct tgctcccttg caacgcctgc ctttacagat agcgggtctt gatttatctg
    67201 tttgggtcgc gattgttttg gttcgatttt taggagaaaa cctagtgcgt tttctggcga
    67261 tgataggatg aataaaggga tttatcagca tttctccata gaagatcgtc catttcttga
    67321 caagggaatg gaatggataa agaaggtaga agatagctat gctccttttt taactccttt
    67381 tatcaatcct catcaggaga agctattaaa gattttggcc aaaacctatg gtcttgcttg
    67441 tagcagtagt ggggaattcg tctcgagtga gtatgttcga gttttattat acccagatta
    67501 tttccaacca gagttttcag attttgaaat atctctccag gaaattgtgt attccaataa
    67561 atttgaacat ttaacgcatg ctaagatttt agggacagtc atcaatcaat tagggattga
    67621 acggaaactt tttggagata tcctagtaga tgaagaacgg gcgcagatta tgattaatca
    67681 gcagtttctt cttctctttc aagatggact aaagaaaatt ggtcgtatac ctgtttcgct
    67741 ggaggaacgt cctttcaccg agaaaataga taagctagaa cagtatcgag aactggattt
    67801 atctgtgtct agttttcgat tagatgttct ttgttcaagt tggagacttg attagtgtga
    67861 gaaaatttgg tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa gagaagaaaa
    67921 aaataaccgt ccagttatta ttaagtaagt gaggaataga atgccaatta catcattaga
    67981 aataaaggac aagacttttg gaactcgatt cagaggtttt gatccagaag aagtcgatga
    68041 atttttagat attgtggttc gtgattacga agatcttgtg cgtgcgaatc atgataaaaa
    68101 tttgcgtatt aagagtttag aagagcgttt gtcttacttt gatgaaataa aagattcatt
    68161 gagccagtct gtattgattg ctcaggatac agctgagaga gtgaaacagg cggcgcatga
    68221 acgttcaaac aatatcattc atcaagcaga gcaagatgcg caacgcttgt tggaagaagc
    68281 taaatataag gcaaacgaga ttcttcgtca agcaactgat aatgctaaga aagtcgctgt
    68341 tgaaacagaa gaattgaaga acaagagccg tgtcttccac caacgtctca aatctacaat
    68401 tgagagtcag ttggctattg ttgaatcttc agattgggaa gatattctcc gtccaacagc
    68461 tacttatctt caaaccagtg atgaagcctt taaagaagtg gttagcgaag tacttggaga
    68521 accgattcca gctccaattg aagaagaacc aattgatatg acacgtcagt tctctcaagc
    68581 agaaatggaa gaattacaag ctcgtattga ggtagccgat aaagaattgt ctgaatttga
    68641 agctcagatt aaacaggaag tggaaactcc aactcctgta gtgagtcctc aagttgaaga
    68701 agagcctctg ctcatccagt tggcccaatg tatgaagaac cagaagtagc tccagtgcat
    68761 ccgacaggtc caacaccagc tacagaaact gttgattcag caccgggatt tgaagcaccg
    68821 caagaatctg ttacaatttt ataagaaata ttctgagaac aatatcttat ccttatattc
    68881 ccagcgagca ggagatggtg tgagtcctgc attccctatc gataagatta tcctctcaaa
    68941 ctatcaagtc tgaatctagt aagatttgac gttccccacg ttacgggata agagggagaa
    69001 agactaaaac tttttccgaa taaaggtggt accacgattt tcgtcctttt tggaagtcgt
    69061 ggtttttaat ttgttattat ttataaagga gataccatga aactcaaaga cacccttaat
    69121 cttgggaaaa ctgaattccc aatgcgtgca ggccttccta ccaaagagcc agtttggcaa
    69181 aaggaatggg aagatgcaaa actttatcaa cgtcgtcaag aattgaacca aggaaaacct
    69241 catttcacct tgcatgatgg ccctccatac gctaacggaa atatccacgt tggacatgct
    69301 atgaacaaga tttcaaaaga tatcattgtt cgttctaagt ctatgtcagg attttacgca
    69361 ccatttattc ctggttggga tactcatggt ctgccaatcg agcaagtctt gtcaaaacaa
    69421 ggtgtcaaac gtaaagaaat ggacttggtt gagtacttga aactttgccg tgagtacgct
    69481 ctttctcaag tagataaaca acgtgaagat tttaaacgtt tgggtgtttc tggtgactgg
    69541 gaaaatccat atgtgacctt gactcctgac tatgaagcag ctcaaattcg tgtatttggt
    69601 gagatggcta ataagggtta tatctaccgt ggtgctaagc cagtttactg gtcatggtca
    69661 tctgagtcag cccttgctga agcagagatt gaataccatg acttggtttc aacttccctt
    69721 tactatgcca acaaggtaaa agatggcaaa ggagttctag atacagatac ttatatcgtt
    69781 gtctggacaa cgactccatt tactatcaca gcctctcgtg gtttgacggt tggtgcagat
    69841 attgattacg ttttggttca acctgctggt gaagctcgta agtttgtcgt tgctgctgaa
    69901 ttattgacta gcttgtctga gaaatttggc tgggctgatg ttcaagtttt ggaaacttac
    69961 cgtggccaag aactcaacca catcgtaaca gaacacccat gggatacagc tgtagaagag
    70021 ttggtaattc ttggtgacca cgttacgact gactctggta caggtattgt ccatacagcc
    70081 cctggttttg gtgaggacga ttacaatgtt ggtattgcta ataatcttga agtcgcagtg
    70141 actgttgatg aacgtggtat catgatgaag aatgctggtc ctgaatttga aggtcaattc
    70201 tatgaaaagg tagttccaac tgttattgaa aaacttggta acctccttct tgcccaagaa
    70261 gaaatctctc actcatatcc atttgactgg cgtactaaga aaccaatcat ctggcgtgca
    70321 gttccacaat ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga cgaaattgaa
    70381 aaagtgaaat tccactcaga atggggtaaa gtccgtcttt acaatatgat ccgtgaccgt
    70441 ggtgactggg ttatctctcg tcaacgtgct tggggtgttc cacttcctat cttctacgct
    70501 gaagatggta cagctatcat ggtagctgaa actattgaac acgtagctca actttttgaa
    70561 gaacatggtt caagcatttg gtgggaacgt gatgccaaag acctcttgcc agaaggattt
    70621 actcatccag gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat ggacgtttgg
    70681 tttgactcag gttcatcatg gaatggagtg gtggtaaacc gtcctgaatt gacttaccca
    70741 gccgaccttt acctagaagg ttctgaccaa taccgtggtt ggtttaactc atcacttatc
    70801 acatctgttg ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca aggttttgcc
    70861 cttgatggta aaggtgagaa gatgtctaaa tctcttggaa ataccattgc tccaagcgat
    70921 gttgaaaaac aattcggtgc tgaaatcttg cgtctctggg taacaagtgt tgactcaagc
    70981 aatgacgtgc gtatctctat ggatatcttg agccaagttt ctgaaactta ccgtaagatt
    71041 cgtaacactc ttcgtttctt gattgccaat acatctgact ttaacccagc tcaagataca
    71101 gtcgcttacg atgagcttcg ttcagttgat aagtacatga cgattcgctt taaccagctt
    71161 gtcaagacca ttcgtgatgc ttacgcaaac tttgaattct tgacaatcta caaggccttg
    71221 gtgaacttta tcaacgttga cttgtcagcc ttctaccttg attttgccaa agatgttgtt
    71281 tacattgaag gtgccaaatc actggaacgc cgtcaaatgc agactgtctt ctatgacatt
    71341 cttgtcaaaa tcaccaaact cttgactcca atccttcctc acactgcgga agaaatctgg
    71401 tcatatcttg agtttgaagc cgaagacttc gtccaattgt cagaattacc agaagttcaa
    71461 acttttgcta accaagaaga aatcttggat acatgggcag ccttcatgga cttccgtgga
    71521 caagcacaaa aagccttgga agaagctcgt aatgcaaaag ttatcggtaa atcacttgaa
    71581 gcacacttga cagtttatcc aaatgaagtt gtgaaaactc tactcgaagc agtaaacagc
    71641 aatgtagctc aacttttgat cgtgtctgag ttgaccatcg cagaagaacc agctccggaa
    71701 gctgccctta gcttcgaaga tgtagtcttc acagttgaac gcgctgcagg tgaagtatgt
    71761 gaccgttgcc gtcgtattga cccaacaaca gcagaacgta gctaccacgc agtcatctgt
    71821 gaccactgtg caagtatcgt agaagaaaac tttgcagatg cagtcgcaga aggatttgaa
    71881 gagaaataag attgaaaagt ctaggtaaaa ctcaatttga gaagaaaaga caactaattt
    71941 tatagtctat taaacgcatt gtatcacgtt tttgaacacc tgatatgatg cgttttttat
    72001 ttattttaaa aatttgcgag gtatgacttt ttatactcaa caagaatcaa agagaaactt
    72061 agcaagctaa cagtagtaat ataaaatagg aatttgatat tagggataag attggtaaat
    72121 agtgtaatat ttttacaaca ataaatttat atagttattt ctggtttctg aaaagtatta
    72181 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    72241 ttaaaaagca aatatgatac aattttattt gaaaaaaaat aaaaaaggag attttattat
    72301 gaaatcaagt ggtatcgtcg gtcttgtggg aggaatttta cttcttattt gtccttttgt
    72361 cttgttggga acagcggtaa atacagctgc tacaactctt aatggaggag ctactgcagg
    72421 ggctttttca ggtgttgcct tactcttgaa tgccttgaag attgcaaatc ttgttcttgg
    72481 tatcattgct attgtttact ataaaggaga taagcatgta ggtgcagctc cgtctgtact
    72541 aatgattgtt tctggtgaag ttagtctcat tccattctta ggatgggttg gggggattct
    72601 tgctattatc ggaggatctc tattccttgc aacattgaag aaattcaaat cagaagaata
    72661 aaaggtattt tagcatgaaa agaacaaaaa agtttatcgg tataggagta gctctattat
    72721 ctctttctct tctagttgca tgtggaacat aaagttcaaa gaatacttca acaagtaatg
    72781 atgagaagac agtagcaaca tccaatagtt caaaagaaac aatcactttc gatacaccgg
    72841 ttgtaacaga cgatgcgatt gaatcaatac gcacttatgc agattatata gatctttata
    72901 aaaatatttt tgatgattat tttactaaag ctgaggaagg tttcaaaggc acaactatgg
    72961 aaaataatga ctcgtttact aaactaaaag agtcaactca aaaattattc gatgcgcaga
    73021 aaaaaaggtt aaataatgaa gatagaatag aaacaaccaa aaacaatgtg attgccaaac
    73081 attgtcaaac agtcctttcc tttttggttt tgactagctt ttttgtgaaa aattgtgtaa
    73141 aatagaatag ataaacgagg ggaaacctcg gaaaatttaa aggagaatcc atctaatggt
    73201 aaaattggtt tttgctcgcc acggtgagtc tgaatggaac aaagctaacc ttttcactgg
    73261 ttgggctgat gttgatttgt ctgaaaaagg tacacaacaa gcgattgacg ctggtaaatt
    73321 gatcaaagaa gctggtatcg aatttgacca agcttacact tcagtattga aacgtgctat
    73381 caaaacaact aacttggctc ttgaagcttc tgaccaattg tgggttccag ttgaaaaatc
    73441 atggcgcttg aacgaacgtc actacggtgg tttgactggt aaaaacaaag ctgaagctgc
    73501 tgaacaattt ggtgatgagc aagttcacat ctggcgtcgt tcatacgatg tattgcctcc
    73561 aaatatggac cgtgatgatg agcactcagc tcacacagac cgtcgttatg cttcacttga
    73621 cgactcagtc attccagatg ctgaaaactt gaaagtgact ttggaacgtg ctcttccatt
    73681 ctgggaagat aaaatcgctc cagctcttaa agatggtaaa aacgtattcg taggagctca
    73741 cggtaactca atccgtgccc ttgtaaaaca catcaaaggt ttgtcagatg atgagatcat
    73801 ggacgtggaa atccctaact tcccaccatt ggtattcgaa ttcgacgaaa aattgaacgt
    73861 tgtttctgaa tactaccttg gaaaataaaa aattgtaagc ctaggattga tttctaggct
    73921 ttttatgtta gtatggaagt atgataagga ataaaaaaca agattatgta ctggcctaca
    73981 agcaaccagc ttcaaccact tacatgggtt gggaagaaga agctttaccg ataggcaatg
    74041 gttctttagg agcaaaagta tttggcctta taggggctga acggattcaa tttaatgaaa
    74101 aaagtctctg gtctggaggt ccacttcctg atagttcaga ttatcagggt ggaaatcttc
    74161 aggatcagta tgttttttta gctgagattc ggcaggcttt ggagaagaga gattacaatc
    74221 tggctaagga actggctgag cagcacctaa ttgggccaaa aacgagtcaa tatgggacct
    74281 atctgtcttt tggggatatt cacattgagt tcagccagca aggtacgact ttgtctcagg
    74341 tgacggacta tcagagacag ctgaatatta gtaaggcact tgcgacgact tcttatgtct
    74401 ataagggaac gcgatttgaa cgtaaagctt ttgcgagttt tccagatgat ctcttgattc
    74461 aatgttttac taaggaaggg ttggaaactc tagattttac tatagaacta tccttgacct
    74521 gtgatttggc ttctgatgga aagtatgagc aggaaaaatc tgattacaag gagtgtaagt
    74581 tggatattac tgattctcat atcttgatga agggaagagt taaggataat gatctgcggt
    74641 ttgctagtta tctagcttgg gaaacggatg gagatattag agtttggtca gatagggttc
    74701 agatatcagg agccagttat gccaatctct tcttggccgc taagacggat tttgcccaaa
    74761 atcctgctag caattatcgc aagaaactag atttagagca acaggtgata gacttggtgg
    74821 acacagctaa agaaaagggc tatacccaat tgaaatcaag gcatatcgag gactaccaag
    74881 ccttattcca gcgtgttcaa ttggatttgg aagctgatgt tgacgcatcc actacagatg
    74941 atttgttaaa aaattataag ccacaagaag ggcaggcttt ggaggagctg ttcttccagt
    75001 atggacggta tttattgatt agttcgtcca gagactgccc agatgctcta ccagctaacc
    75061 tacagggagt ctggaatgcg gtcgacaatc ctccttggaa ttcggactat cacttaaatg
    75121 tcaatctgca gatgaattat tggccagcct atgttaccaa tctcctagag acggtctttc
    75181 cagtcatcaa ctatgtagat gatttgcgtg tctatggtcg tctagcggct gtaaagtatg
    75241 caggaatcgt ctctcaaaaa ggtgaggaaa atggttggtt ggttcatact caagcgactc
    75301 cctttggttg gacggcacct ggttgggatt actattgggg ttggtcacca gctgccaatg
    75361 cgtggatgat gcaaaccgtt tatgaagcct attcatttta tagggaccaa gactatctca
    75421 gggagaaaat ttatcccatg ttgagggaaa cggttcgttt ttggaatgcc tttttacata
    75481 aggatcagca ggcgcagcgt tgggtctctt ctccgtctta ttccccagaa catgggccga
    75541 tttcgattgg caatacctat gaccaatctc tgatttggca gttatttcat gattttattc
    75601 aggctgctca ggaattggga ctggatgagg acttgttgac tgaggttaag gagaagtctg
    75661 atttactaaa tcctttgcaa atcactcaat ctggtcgaat cagggagtgg tatgaggagg
    75721 aagagcagta ttttcaaaat gagaaagtgg aggcccagca tcggcacgct tcccatctag
    75781 tgggactcta ttctggcaat ctctttagct acaagggaca agagtatatt gaagcggcgc
    75841 gtgctatcct caatgatcgt ggagatggcg gcacaggctg gtccaaggct aataagatca
    75901 atctctgggc gcgtttggga gatggcaatc gagcccataa attattggca gagcagttaa
    75961 agacatccac cttgccaaat ctttggtgta gccatcctcc ttttcagata gatggtaatt
    76021 ttggtgctac tagtggcatg gcagaaatgt tactccagtc tcatgcagct tatctggtac
    76081 ctctagctgc cctacctgat gcttggtcaa caggttctgt ttcaggctta atggcacgtg
    76141 gacattttga agtgagcatg agctgggaag ataaaaaact cttacagttg accattttat
    76201 caaggagtgg aggagatttg cgagtttctt atccagatat tgagaagagt gtgattaaaa
    76261 tgaatcaaga aaaaataaaa gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag
    76321 cagaaggtga tcttgttcaa ttttattttt aagaagatgt tataaggcag taatttgaaa
    76381 cttcctttta ataaggattt gagaatatag gcagtttcca actagttgaa aaagcgttat
    76441 aatgataata ggaagtaata ctcaatgaaa atcaaagagc acaaactagg aagctagccg
    76501 caggttgctc aaaacagtgt tttgaggttg tagatggaag ctgacgtggt ttgaagagag
    76561 attttcgagg agtataattt gtttgataga gggtgggtct gatggcttat attgagatga
    76621 aacactgtta caagcgttat caggttgggg acacggagat tgtggccaat cgtgatgtga
    76681 attttgagat tgaaaagggg gagctggtta ttatccttgg tgcttcaggt gcaggcaagt
    76741 caacagttct taaccttctt gggggaatgg ataccaatga tgaaggggaa atctggattg
    76801 atggtgttaa tattgcggat tatagttccc accagcgtac caattaccgt agaaatgatg
    76861 tggggtttgt ttttcagttt tataatctag tttctaatct gacagctaag gaaaatgtgg
    76921 aactggcttc tgaaattgtg acagatgcct tgaatcctga tcaggtcttg acagatgtag
    76981 gtctggctca tcgtctcaat aactttccag cccagctttc tggaggggag caacagcgag
    77041 tctccattgc acgcgcggta gccaaaaatc ctaaaattct cctttgtgat gaaccgactg
    77101 gagccttgga ttatcagacg ggcaagcagg ttttgaaaat tctccaagac atgtctcgtc
    77161 aaaagggagc gacggtgatc atcgtgactc ataatggagc tttggcgccc attgctgatc
    77221 gcgtgattca aatgcacgat gccagtgtca aggatgtggt gctcaaccag catcctcagg
    77281 atattgacag tttggagtac tagcatgatc aagcgaaaaa cttattggaa ggacttaatt
    77341 cagtccttca caggctccaa ggggcgtttt ttatccatct tgatcctgat gatgttggga
    77401 tctctagcct tagtaggcct caaagtaacc agtcccaaca tggaggcgac agctaatgct
    77461 tatttaacaa ctgctcaaac cttggatttg gcagtcatgt ctaactatgg cttggatcaa
    77521 gcagaccaag aagaactaaa acagacggag ggcgcagagg tcgagtttgg ctatttgaca
    77581 gatgtgacta tggataatgg gcaggatgcc attcggctgt actccaaacc agagcgaatt
    77641 tcaacctttc agctaagaaa gggacgactt cctcagtcag acaaggaaat cgctttggcc
    77701 actcatttgc aaggccaata cagcgtggga caggagatta gttttaaaga aaaagaagag
    77761 ggtcattcct ctttaaaaga ccatacttat accattactg gttttgtgga ttcggctgaa
    77821 atcctctccc agcgagatat gggctacgca ggaagtggaa gtgggactct gacagcctat
    77881 ggggtgattt tacctagtca gtttgatcag aaagtctaca atatagctcg tttgaaatat
    77941 caagatttag caggtttaaa tgccttttca tcagcttatg aagaaaaatc caagcaacat
    78001 caggaagacc ttgaacaaac tttatcagat aatggcaagg tacgtctgca acttttgaaa
    78061 aaagaaggac aagagtctct agacaagggg caagagaccc ttgacaaggc tcagactaat
    78121 ttgcaggaag gcaagcgtcg tttagcagct gctcaagctc gtatacaggc tcaagaaagt
    78181 caactagcct tgtttcctca agttcagaga gagcaggcta gtgctcaact tacccaagcc
    78241 aagcaggaat tgggcaagga agaggataaa ctaaagcaag ctgaacaaaa tctagcccaa
    78301 gaaaaggaaa aattagaaaa acatcagcaa gtcttggacg atttggcgga gccaaggtat
    78361 caggtctata atcgtcagac catgccaggt ggtcagggct atcttatgta tagcaatgct
    78421 tcatccagta ttcgagcagt gggcaatatc tttcctgtgg tactttatgc cgtagcatcc
    78481 atggtgacct ttacgaccat gactcgcttt gtagacgaag agcgaactca tgcagggatt
    78541 tttaaggcct tgggttaccg tagtaaggat attatcacca agtttctcct ttatggacta
    78601 gtagctggga ctgtcggaac ggctctaggt agtatacttg gtcattattt gctagccagt
    78661 gtaatttcaa gtgtcattac aaaaggcatg gtggtgggag aaacccagat tcagttctat
    78721 tggacctata gcttactagc tcttgtcttg agctggttgg cgagtgtgtt accagcctat
    78781 ctggtggctt ggagggaact tcatgccgaa gcagcccagc ttctacttcc taaacctcct
    78841 gtcaaaggag ctaaaatctt attggagcgt atcggtttta tctggcgtcg tctcagtttt
    78901 actcataagg taacagcccg caacatcttt cgttataagc agagaatgtt gatgacaatc
    78961 tttggtgtgg caggttctgt agctctgctc tttgcaggtt tgggaatcca atcttctgta
    79021 gcaggagttc cgtctaaaca gtttcaacaa atccaacagt atcagatgct tgtctctgaa
    79081 aatcctagtg cgaccaatca ggacaaggta gagctagcag aagtgttgaa agggcaggag
    79141 atactagcct accagaaaat ctattctaaa acgctagaca aggatttcaa aggcaaggct
    79201 ggtcttcaaa acattactct tatgatgata gagaaggaag atttgactcc ctttatccat
    79261 cttcaacatc atcagcagga gctgacatta aaagatggca tcgttattac agctaaactc
    79321 gcccagctgg caggtgtcaa ggttgggcag actttagaaa ttgaaggtaa ggaactaaag
    79381 gtcgctgcta ttactgagaa ctacgttggt cactttattt atatgagtca ggctagctat
    79441 gagcaacttt acggacagct accccaagcc aacacttatc tggtctcatt aagggatacc
    79501 agtgcaacta gtatcgaaag tcaggcgggc ttgcttatga atcaatctgc ggtgtccagc
    79561 gttgtccaaa atgcttcagc cattcgactc tatcgctagc tcactcaatc agaccatgac
    79621 catcttggtc atcgtatcag ttctattagc tattgtcatc ctttacaatc tgaccaatat
    79681 caacgtagct gagagaatcc gtgaactctc cactatcaag gttctcggtt ttcataataa
    79741 tgaagtcacc ctctacattt accgtgagac gattgtgctg tcccttgtgg gaatcgtact
    79801 tggtctggta gctggtttct atttacacca atttttgatt caaatgattt cgcctgcgac
    79861 tattctcttt tatccgcagg taggctggga agtctatgta atcccagtgg caacagtaag
    79921 catcattttg accttgcttg gtttcttcgt caattattat ctgagaaagg ttgatatgtt
    79981 agaagccctg aaatctgtag agtaaggtag ttatttttag ctgattgaac ttctatttac
    80041 taatattcaa aaatcctctg tcacaaagag cagggagctc tttgtgacag aggatttttt
    80101 ctatagggct ttagcagctg caattgcggc ttcgaagttt ggctcagaat tgatattatc
    80161 cacgtattca acgtagcgaa tcgtattgtc agtatcgagg acaaagactg cgcgtgctaa
    80221 taggtgccat tcgttgatca agagggcata atcgcgcccg aaagaatggt caaagtagtc
    80281 tgaaagcata atggcattgt caaggccttc agcaccgcac caacgttttt gagcaaaagg
    80341 taggtccatt gaaacagtca atacgaccgt gttgtccagt ccagccaatt cttcattaaa
    80401 acgacgtgtt tgagttgagc agatgcctgt atcgatagaa ggaacgacac tcaagacttt
    80461 tttcttgcca tcaaaatcag ccagagattt tttagaaaga tctgttgtag taagagaaaa
    80521 atcaagcgcc ttgtcgccga cttgtagttg tttacctgta aagctcacag gatttccgag
    80581 aaaagttacc ataggatact ccaatctttt ttcttccatt gtatctgaaa cagtcagaat
    80641 tttccaatga tttgaccgga aatgtgggca tagaaaaaac gccagctcac atgagaatga
    80701 cgtttttcag aggcttattt tgccaatcct tcagcaatct tgtcaaggtt gtatttcatc
    80761 atgctgtagt agctgtcgcc ttctttacct tgttctgcga tagagtcagt aaagatttgt
    80821 gcgtagattg ggatgtttgt gtcttgagaa acagttttca ttggacggtc atccacactt
    80881 gattctacaa agagtgatgg aacttttgtt tggcgaagtt tttcaaccaa ggtcttgatt
    80941 tgttcaggag ttccttcttc ttcagtattg atttcccaga tgtaagcact tgggacacca
    81001 taggctttag agaagtattt gaatgctcct tcgctggtta caatgagttt cttttcagca
    81061 gggatcttat taaatttatc cttactttct ttatcaagtt tgtctaactt atcagtatat
    81121 tctttgagat ttttttcata gaattcttta ttgttagggt ctttggcgct caattgtttg
    81181 gcgatatttt tagcaaaaat aataccgttt tcaaggttaa gccaagcgtg tgggtcttct
    81241 tttccttttt cattttgacc ttcaaggtag ataacatcaa cgccgtcgct gactgcgaag
    81301 tagtctttgt tttcagtttt cttggcattt tctaccaatt ttgtaaacca agcattgcca
    81361 cctgtttcaa ggttgatacc gttatagaaa atcaaatcag cctcagaagt tttcttaacg
    81421 tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa tcggaacgat actatgaagg
    81481 tcaattttgt caccagcaat atttttagta atatcagcga tgattgagtt tgtagcaaca
    81541 acttttagtt tttgaccaga agttgtatct ttttttccgc tagcacatgc tacaagaatg
    81601 attgcagaaa gaaagagaac gagtaatgta cctaattttt tcattagatc ctccaaatta
    81661 ttagggcttt gccccttatt ttaacaaatg tttatttttc agtttcaaat atcgttgttt
    81721 gggagcgata aagaagctaa tgagaaagaa actagcagct gtaagcacga tactagaacc
    81781 tgccgcaaca ttaaaactat agccaataaa gagtcccaaa actgaagcag tagctccgaa
    81841 ggttgaggaa aggaaaatca tgcttttcag actattagca tacagataag cagttgcagc
    81901 tggggtaatc agcatggcta caatcaggat agttccgaca ctttgcatgg ctgtcacaga
    81961 cacgagagtc aggagtacca tgagaaggta gtgatagaaa ttgacaggca ttcccatggc
    82021 tttagccaag agttcatcaa aggaagttat caagagttgc ttgaagaaaa tccagattaa
    82081 caagaggatg gctgccccca cacccatagt aataaacata tccgtatctt ggacggccag
    82141 gatattacca aaaaggatat ggaaaaggtc agttgaactt ttagcgacac caatcaagat
    82201 gataccgagg gctaagaaag aagaaaaggt aatgccgatg gcggtatcgc ttttgataat
    82261 cgagtttcct ttgatgtagg taatgatgat ggcagctagc aatccaaaga caatggctcc
    82321 gataaagaag tcaaggccca agatgaagga gagggctaca cctggtaaga cagcatgtga
    82381 aatggcatct cccatgagtg acatcccgcg tagaataatg aaacatccca cagctccagc
    82441 tacaatcccg acgacaatag ctgttatcaa ggcattttgt aggaaatgga atttttgcaa
    82501 tccatcgata aattctgcaa tcataggtca cctccattga aaaagagttg attaccgtaa
    82561 gcttctttta gattggtttc ggtaaaagtt tcttttgttg gaccaaaggc aatcacttct
    82621 cgattgacaa gtaagacttg atcgaagtag tggggaatct tgctgaggtc gtggtgaacg
    82681 atgagaaccg tcttcccagc ttttttcaaa tctctcagcg tattcatgat gatttcctca
    82741 ctgacagagt caatcccagc aaagggttca tccaagagga tatagtcggc ttcctgcacc
    82801 aaacatctgg caatcaaaac ccgctggaat tgacctccag acagttgact aatttgacgt
    82861 tcagcgtagt cagctaggcc gacgatttca agggcctctt gcactttctt ccaatgttta
    82921 gcctttaaac ttcgaaagag aggaatagag ggaaatagtc ctaacgagac gcattccttg
    82981 accttgatgg gaaagttgta gtcgatattg attttttgtt cgacataggc aattcggtgt
    83041 aaggattttt taacttcctt gtcatcgaga aatgcctgac cttgatgtgg gataattccc
    83101 agcatacctt ttaatagtgt tgatttccca gcgccgtttg gaccaatgat gccggtaatt
    83161 gttggtccat ggagcactag tgaaatatcc ttaagtgcca acgtttcttt gtaggagaca
    83221 ctgaggtttt cgatacgtat cataaacttg tattcctcct gtctcttaat atacattaaa
    83281 aaaaaaatta agtcaagtta atttttgaaa aaattaaaat aataactgaa aaataga
//
LOCUS       DAVBED010000002        80116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBED010000002 DAVBED010000000
VERSION     DAVBED010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.002"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQ547_000077"
     CDS             complement(134..1882)
                     /locus_tag="VQ547_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542011.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQ547_000078"
     CDS             complement(1884..3608)
                     /locus_tag="VQ547_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542012.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ547_000079"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ547_000079"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2542013.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQ547_000080"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQ547_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQ547_000081"
     CDS             complement(4899..5768)
                     /locus_tag="VQ547_000081"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2542014.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQ547_000082"
     CDS             complement(5770..7056)
                     /locus_tag="VQ547_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2542015.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ547_000083"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ547_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2542016.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQ547_000084"
     CDS             complement(8144..9178)
                     /locus_tag="VQ547_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2542017.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQ547_000085"
     CDS             complement(9207..10640)
                     /locus_tag="VQ547_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2542018.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQ547_000086"
     CDS             complement(10656..11642)
                     /locus_tag="VQ547_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2542019.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQ547_000087"
     CDS             complement(11644..12747)
                     /locus_tag="VQ547_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2542020.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQ547_000088"
     CDS             complement(12737..13582)
                     /locus_tag="VQ547_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2542021.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ547_000089"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ547_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2542022.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ547_000090"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ547_000090"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2542023.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQ547_000091"
     CDS             complement(15977..16453)
                     /locus_tag="VQ547_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2542024.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ547_000092"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ547_000092"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2542025.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQ547_000093"
     CDS             complement(17821..18159)
                     /locus_tag="VQ547_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2542026.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQ547_000094"
     CDS             complement(18170..19273)
                     /locus_tag="VQ547_000094"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2542027.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ547_000095"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ547_000095"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2542028.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQ547_000096"
     CDS             complement(20459..21526)
                     /locus_tag="VQ547_000096"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2542029.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQ547_000097"
     CDS             complement(21545..22399)
                     /locus_tag="VQ547_000097"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2542030.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQ547_000098"
     CDS             complement(22389..23066)
                     /locus_tag="VQ547_000098"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2542031.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQ547_000099"
     CDS             complement(23063..24226)
                     /locus_tag="VQ547_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2542032.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQ547_000100"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQ547_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQ547_000101"
     CDS             complement(26526..27275)
                     /locus_tag="VQ547_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542033.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQ547_000102"
     CDS             27454..28908
                     /locus_tag="VQ547_000102"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2542034.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ547_000103"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ547_000103"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2542035.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQ547_000104"
     CDS             complement(31638..32123)
                     /locus_tag="VQ547_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2542036.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQ547_000105"
     CDS             complement(32398..32637)
                     /locus_tag="VQ547_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542037.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQ547_000106"
     CDS             complement(32890..33960)
                     /locus_tag="VQ547_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2542038.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQ547_000107"
     CDS             complement(33957..34730)
                     /locus_tag="VQ547_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542039.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQ547_000108"
     CDS             complement(34727..35533)
                     /locus_tag="VQ547_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542040.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQ547_000109"
     CDS             complement(35514..36671)
                     /locus_tag="VQ547_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542041.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ547_000110"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ547_000110"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2542042.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQ547_000111"
     CDS             complement(37792..38544)
                     /locus_tag="VQ547_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2542043.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ547_000112"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ547_000112"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2542044.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQ547_000113"
     CDS             39427..40698
                     /locus_tag="VQ547_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2542045.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQ547_000114"
     CDS             complement(40718..41533)
                     /locus_tag="VQ547_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2542046.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ547_000115"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ547_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2542047.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ547_000116"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ547_000116"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2542048.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ547_000117"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ547_000117"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2542049.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ547_000118"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ547_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2542050.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ547_000119"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ547_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2542051.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ547_000120"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ547_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2542052.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQ547_000121"
     CDS             complement(47183..48487)
                     /locus_tag="VQ547_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2542053.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQ547_000122"
     CDS             complement(48488..49261)
                     /locus_tag="VQ547_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2542054.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQ547_000123"
     CDS             complement(49251..49529)
                     /locus_tag="VQ547_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2542055.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQ547_000124"
     CDS             complement(49529..49930)
                     /locus_tag="VQ547_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2542056.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQ547_000125"
     CDS             complement(50140..50757)
                     /locus_tag="VQ547_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2542057.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQ547_000126"
     CDS             complement(50747..51520)
                     /locus_tag="VQ547_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2542058.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQ547_000127"
     CDS             complement(51531..52268)
                     /locus_tag="VQ547_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2542059.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQ547_000128"
     CDS             complement(52273..53403)
                     /locus_tag="VQ547_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2542060.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQ547_000129"
     CDS             complement(53487..53876)
                     /locus_tag="VQ547_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2542061.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQ547_000130"
     CDS             complement(53892..54275)
                     /locus_tag="VQ547_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2542062.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQ547_000131"
     CDS             complement(54276..55064)
                     /locus_tag="VQ547_000131"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2542063.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQ547_000132"
     CDS             complement(55057..55992)
                     /locus_tag="VQ547_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2542064.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQ547_000133"
     CDS             complement(56122..56298)
                     /locus_tag="VQ547_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2542065.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQ547_000134"
     CDS             complement(56438..57145)
                     /locus_tag="VQ547_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2542066.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQ547_000135"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQ547_000135"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2542067.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQ547_000136"
     CDS             complement(58995..59384)
                     /locus_tag="VQ547_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2542068.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQ547_000137"
     CDS             complement(59438..60145)
                     /locus_tag="VQ547_000137"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2542069.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQ547_000138"
     CDS             complement(60845..61396)
                     /locus_tag="VQ547_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542070.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ547_000139"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ547_000139"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2542071.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQ547_000140"
     CDS             complement(62615..64075)
                     /locus_tag="VQ547_000140"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2542072.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQ547_000141"
     CDS             complement(64191..64679)
                     /locus_tag="VQ547_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542073.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQ547_000142"
     CDS             complement(64669..64878)
                     /locus_tag="VQ547_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542074.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQ547_000143"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQ547_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQ547_000144"
     CDS             complement(66002..66808)
                     /locus_tag="VQ547_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542075.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..67942)
                     /locus_tag="VQ547_000145"
                     /pseudo
     CDS             complement(67214..67942)
                     /locus_tag="VQ547_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68178..68489)
                     /locus_tag="VQ547_000146"
     CDS             complement(68178..68489)
                     /locus_tag="VQ547_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542076.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68504..69790)
                     /locus_tag="VQ547_000147"
     CDS             complement(68504..69790)
                     /locus_tag="VQ547_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2542077.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70414..70596
                     /locus_tag="VQ547_000148"
     CDS             70414..70596
                     /locus_tag="VQ547_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2542078.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            70606..70971
                     /locus_tag="VQ547_000149"
     CDS             70606..70971
                     /locus_tag="VQ547_000149"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2542079.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            70968..72158
                     /locus_tag="VQ547_000150"
     CDS             70968..72158
                     /locus_tag="VQ547_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2542080.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72673..73665)
                     /locus_tag="VQ547_000151"
     CDS             complement(72673..73665)
                     /locus_tag="VQ547_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542081.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73825..75579
                     /locus_tag="VQ547_000152"
     CDS             73825..75579
                     /locus_tag="VQ547_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542082.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75563..77284
                     /locus_tag="VQ547_000153"
     CDS             75563..77284
                     /locus_tag="VQ547_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542083.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77295..77924
                     /locus_tag="VQ547_000154"
     CDS             77295..77924
                     /locus_tag="VQ547_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2542084.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            77825..78382
                     /locus_tag="VQ547_000155"
     CDS             77825..78382
                     /locus_tag="VQ547_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2542085.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78370..79734
                     /locus_tag="VQ547_000156"
     CDS             78370..79734
                     /locus_tag="VQ547_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542086.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        24632 a        17071 c        14696 g        23717 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac aactgctcat
    67561 tttcagatgg tgtaccatag taaaatcctg tagccagttc acgttgggca accttccaca
    67621 tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat
    67681 ccacaaccgc cttgtagcag ttggttactg ttaatacata gtgaatagac tccatacgtc
    67741 cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg tcaatcatag
    67801 acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt
    67861 ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac
    67921 cacggttggc atcacgcata ctctagacgc aattctaatc ttttagactt tgcataataa
    67981 ctgttaaaca gttgaaaatt aacccagttt taacaagtag tcaaaatacc agataaagga
    68041 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
    68101 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
    68161 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
    68221 aagcgagaaa aacaaaaggg gcaacttaag ctttctttat attgcttata tgttagtagt
    68281 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
    68341 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaaaca
    68401 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
    68461 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
    68521 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    68581 ctccagcttg aacaggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    68641 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    68701 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatag
    68761 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    68821 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    68881 tagccagttc acgttgggca accttccaca tctcgtccac taagttttgt ttgatggctt
    68941 caaacttttc agaactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    69001 ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc acaccatttt
    69061 caatcatatc tggaatgtgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
    69121 ctagaatctc acccttcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    69181 atttccaacg gcatgactga gaacacccac cacggttggc atcacgcata ctcatgtggt
    69241 ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca aaggcttcaa
    69301 tttcaacatc tgtacgtttg cggatttcag ctaattcttt cattgaaacc tcacgtgcta
    69361 aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag ttagtggcac
    69421 tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca atcataatca
    69481 aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta cgaaaccact
    69541 caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca tagaccttgg
    69601 caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta aagtttcccg
    69661 cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct ccatactgaa
    69721 cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga cgttttaatg
    69781 tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc ttctcatttt
    69841 atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc taatctttta
    69901 gactttgcat aataactatt aaacagtcga aaattacccc agttttaaca agtagtcaaa
    69961 aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat atataaatta
    70021 gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt gatacagtct
    70081 agaatatcgc ttttttattt attattctga tataaaactg ttagaattga ttttttgttt
    70141 tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt ggaaaaatga
    70201 gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga aaaaagctca
    70261 aagaatttat taaaccatgt tataatagat atagctataa ttttatttat aacaagagga
    70321 tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac
    70381 ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat
    70441 ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa
    70501 aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta
    70561 tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa
    70621 aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa
    70681 ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata
    70741 aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga
    70801 actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa
    70861 tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    70921 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    70981 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    71041 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    71101 attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    71161 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    71221 ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    71281 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    71341 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    71401 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    71461 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    71521 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    71581 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    71641 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    71701 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    71761 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    71821 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    71881 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    71941 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    72001 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    72061 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    72121 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    72181 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    72241 cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta gattctattt
    72301 tttataatat cactaaatcc acctaattat aggacgtttt cagattttta gtcccgtccc
    72361 agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct
    72421 taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa
    72481 taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg
    72541 cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat
    72601 caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg
    72661 taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt
    72721 acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc
    72781 agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag
    72841 agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt
    72901 ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc
    72961 ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt
    73021 atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact
    73081 tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca
    73141 atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg
    73201 aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat
    73261 tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa
    73321 aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg cggtaatagt
    73381 ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac
    73441 atagtctgac atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg
    73501 tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg cataagttga
    73561 attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca
    73621 ttcatctact ttcatataat cttttacaaa atcataatat gacataacac actatccctt
    73681 ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta attataacag
    73741 atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg
    73801 atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa
    73861 gataagaaat atcttggggt tttggccata attttttctg ctatatctgc tgtacttaca
    73921 gtatatggat attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta
    73981 tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt
    74041 tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga
    74101 aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct
    74161 ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagctcac
    74221 atgattccag atagctctca ggcaatagtc acacctatac ttgtccttgt acttggcttt
    74281 atagtaagta taagagttgg cataattttg cttgctctta ctataattgg tggcttaatt
    74341 ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa
    74401 ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca
    74461 aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat
    74521 gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg
    74581 attgcaattt taattattcc tatagtttat tttatgacta gcttagctag cgcagaggtg
    74641 attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg
    74701 agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag
    74761 gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa
    74821 aactataata tagaatttga gaatgttagc tttgcttata atgataaagc tatcattgaa
    74881 aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca
    74941 ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata
    75001 aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc
    75061 tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt agctttagct
    75121 aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta
    75181 atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta
    75241 tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt
    75301 attattatgg atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa
    75361 gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca
    75421 attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct
    75481 gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt
    75541 gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga
    75601 tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa
    75661 catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa
    75721 aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct
    75781 ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat
    75841 aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc
    75901 cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc
    75961 aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc
    76021 gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat
    76081 acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa
    76141 aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt
    76201 atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga gaatacactt
    76261 aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc
    76321 tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct
    76381 ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa
    76441 agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca
    76501 aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa
    76561 agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc
    76621 taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt
    76681 gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga
    76741 tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt
    76801 ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggtaagcaag atgcaagtga
    76861 cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga
    76921 taaaggtttc gatacagtta ttggtgaaaa cggagctgag ctatcaggag gagaaagaca
    76981 aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat
    77041 aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt
    77101 taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa
    77161 gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca
    77221 aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta
    77281 ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta agtatcggtg
    77341 tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa
    77401 tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat
    77461 ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg
    77521 tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa
    77581 tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt
    77641 atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa
    77701 aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt
    77761 taataactta tcctcacatg gctttaatag ccttaggtgc tttcttagga ggaattcttg
    77821 gagcatatat aggcaaggct ctattgaaaa aacacttttc aaatggatta tattgtgtgg
    77881 gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat
    77941 gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt
    78001 tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc
    78061 aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga
    78121 gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa
    78181 atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat cagatgacat
    78241 tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg
    78301 cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg
    78361 aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta
    78421 gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga
    78481 agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca
    78541 aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa
    78601 atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat
    78661 acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac
    78721 aggcgtttga aggatatact tgagatattc ccgataaaaa atcttttgaa cagaaatata
    78781 tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt
    78841 acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt
    78901 ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat
    78961 agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt
    79021 aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta
    79081 agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag
    79141 tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat
    79201 atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca
    79261 acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag
    79321 ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta
    79381 aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt
    79441 gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg
    79501 catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc
    79561 aagacttctc catttatctt ttttgacgaa ccttcaagtg gtatagatta ttccaatatg
    79621 ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt
    79681 tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga
    79741 gtctgttaaa catgtctata gaactggtaa attgtctaaa aatttaaaag atactaacac
    79801 atattgatat ttattagaaa attaacttca ggatttttac agtatttata aactttataa
    79861 tatgtattta tagtattaat aatttccata tctttaggga aattatttat ttacttacca
    79921 taattaaaga gatgagagat aaatatcggc agtcttcgga ctgcctttat ttttttactt
    79981 aatttaatgc agtaaatcat acgattgaaa ggaatctgcg ttatatgcta taattaggta
    80041 gttaatctat acatttagaa aggtaaaata tagaattgga gaatgatatg ggattttcat
    80101 ataataaatt gtaacc
//
LOCUS       DAVBED010000003        79768 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBED010000003 DAVBED010000000
VERSION     DAVBED010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.003"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..722
                     /locus_tag="VQ547_000157"
     CDS             <1..722
                     /locus_tag="VQ547_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2542087.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RLEAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQ
                     AAKACPRFSPAFKAYLKTKLE"
     gene            complement(1023..2912)
                     /locus_tag="VQ547_000158"
     CDS             complement(1023..2912)
                     /locus_tag="VQ547_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2542088.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3050..4615
                     /locus_tag="VQ547_000159"
     CDS             3050..4615
                     /locus_tag="VQ547_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2542089.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4615..5379
                     /locus_tag="VQ547_000160"
     CDS             4615..5379
                     /locus_tag="VQ547_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2542090.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(5578..5793)
                     /locus_tag="VQ547_000161"
     CDS             complement(5578..5793)
                     /locus_tag="VQ547_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542091.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ547_000162"
     CDS             complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ547_000162"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2542092.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7964..8320)
                     /locus_tag="VQ547_000163"
     CDS             complement(7964..8320)
                     /locus_tag="VQ547_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2542093.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8558..8794)
                     /locus_tag="VQ547_000164"
     CDS             complement(8558..8794)
                     /locus_tag="VQ547_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542094.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ547_000165"
     CDS             complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ547_000165"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2542095.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ547_000166"
     CDS             complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ547_000166"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2542096.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10458..12158)
                     /locus_tag="VQ547_000167"
     CDS             complement(10458..12158)
                     /locus_tag="VQ547_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2542097.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12359..14026)
                     /locus_tag="VQ547_000168"
     CDS             complement(12359..14026)
                     /locus_tag="VQ547_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2542098.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(14029..14394)
                     /locus_tag="VQ547_000169"
     CDS             complement(14029..14394)
                     /locus_tag="VQ547_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2542099.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14551..14739)
                     /locus_tag="VQ547_000170"
     CDS             complement(14551..14739)
                     /locus_tag="VQ547_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2542100.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14855..15031)
                     /locus_tag="VQ547_000171"
     CDS             complement(14855..15031)
                     /locus_tag="VQ547_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2542101.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(15142..15291)
                     /locus_tag="VQ547_000172"
     CDS             complement(15142..15291)
                     /locus_tag="VQ547_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2542102.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(15603..17147)
                     /locus_tag="VQ547_000173"
     CDS             complement(15603..17147)
                     /locus_tag="VQ547_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2542103.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17360..17662
                     /gene="gatC"
                     /locus_tag="VQ547_000174"
     CDS             17360..17662
                     /gene="gatC"
                     /locus_tag="VQ547_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2542104.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17662..19128
                     /gene="gatA"
                     /locus_tag="VQ547_000175"
     CDS             17662..19128
                     /gene="gatA"
                     /locus_tag="VQ547_000175"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2542105.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            19128..20570
                     /gene="gatB"
                     /locus_tag="VQ547_000176"
     CDS             19128..20570
                     /gene="gatB"
                     /locus_tag="VQ547_000176"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2542106.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20699..21259
                     /gene="efp"
                     /locus_tag="VQ547_000177"
     CDS             20699..21259
                     /gene="efp"
                     /locus_tag="VQ547_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2542107.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21281..21670
                     /locus_tag="VQ547_000178"
     CDS             21281..21670
                     /locus_tag="VQ547_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2542108.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21663..22085
                     /gene="nusB"
                     /locus_tag="VQ547_000179"
     CDS             21663..22085
                     /gene="nusB"
                     /locus_tag="VQ547_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2542109.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22134..22511)
                     /locus_tag="VQ547_000180"
     CDS             complement(22134..22511)
                     /locus_tag="VQ547_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2542110.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ547_000181"
     CDS             complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ547_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2542111.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(23196..23963)
                     /locus_tag="VQ547_000182"
     CDS             complement(23196..23963)
                     /locus_tag="VQ547_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2542112.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23960..24826)
                     /locus_tag="VQ547_000183"
     CDS             complement(23960..24826)
                     /locus_tag="VQ547_000183"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2542113.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ547_000184"
     CDS             complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ547_000184"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2542114.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ547_000185"
     CDS             complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ547_000185"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2542115.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26661..27146)
                     /locus_tag="VQ547_000186"
     CDS             complement(26661..27146)
                     /locus_tag="VQ547_000186"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2542116.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ547_000187"
     CDS             complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ547_000187"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2542117.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ547_000188"
     CDS             complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ547_000188"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2542118.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ547_000189"
     CDS             complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ547_000189"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2542119.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ547_000190"
     CDS             complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ547_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2542120.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31177..31401)
                     /locus_tag="VQ547_000191"
     CDS             complement(31177..31401)
                     /locus_tag="VQ547_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2542121.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31461..32435)
                     /locus_tag="VQ547_000192"
     CDS             complement(31461..32435)
                     /locus_tag="VQ547_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2542122.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32435..32869)
                     /locus_tag="VQ547_000193"
     CDS             complement(32435..32869)
                     /locus_tag="VQ547_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2542123.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32963..33748)
                     /locus_tag="VQ547_000194"
     CDS             complement(32963..33748)
                     /locus_tag="VQ547_000194"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2542124.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34073..35437
                     /locus_tag="VQ547_000195"
     CDS             34073..35437
                     /locus_tag="VQ547_000195"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2542125.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35440..35811
                     /locus_tag="VQ547_000196"
     CDS             35440..35811
                     /locus_tag="VQ547_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2542126.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36025..37299
                     /gene="serS"
                     /locus_tag="VQ547_000197"
     CDS             36025..37299
                     /gene="serS"
                     /locus_tag="VQ547_000197"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2542127.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37324..38223)
                     /locus_tag="VQ547_000198"
     CDS             complement(37324..38223)
                     /locus_tag="VQ547_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2542128.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(38333..38881)
                     /locus_tag="VQ547_000199"
     CDS             complement(38333..38881)
                     /locus_tag="VQ547_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2542129.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39099..40421)
                     /locus_tag="VQ547_000200"
     CDS             complement(39099..40421)
                     /locus_tag="VQ547_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2542130.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40512..40600)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40764..43100)
                     /locus_tag="VQ547_000201"
     CDS             complement(40764..43100)
                     /locus_tag="VQ547_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2542131.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(43204..43752)
                     /locus_tag="VQ547_000202"
     CDS             complement(43204..43752)
                     /locus_tag="VQ547_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2542132.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ547_000203"
     CDS             complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ547_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2542133.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44138..45019
                     /locus_tag="VQ547_000204"
     CDS             44138..45019
                     /locus_tag="VQ547_000204"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2542134.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45023..45637
                     /gene="lepB"
                     /locus_tag="VQ547_000205"
     CDS             45023..45637
                     /gene="lepB"
                     /locus_tag="VQ547_000205"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2542135.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45916..48282
                     /locus_tag="VQ547_000206"
     CDS             45916..48282
                     /locus_tag="VQ547_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2542136.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(48330..49613)
                     /locus_tag="VQ547_000207"
     CDS             complement(48330..49613)
                     /locus_tag="VQ547_000207"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2542137.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49807..50166)
                     /locus_tag="VQ547_000208"
     CDS             complement(49807..50166)
                     /locus_tag="VQ547_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2542138.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(50465..51094)
                     /locus_tag="VQ547_000209"
     CDS             complement(50465..51094)
                     /locus_tag="VQ547_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2542139.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(51139..51378)
                     /locus_tag="VQ547_000210"
     CDS             complement(51139..51378)
                     /locus_tag="VQ547_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542140.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(51528..51794)
                     /locus_tag="VQ547_000211"
                     /pseudo
     CDS             complement(51528..51794)
                     /locus_tag="VQ547_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51819..52127)
                     /locus_tag="VQ547_000212"
     CDS             complement(51819..52127)
                     /locus_tag="VQ547_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2542141.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(52052..52294)
                     /locus_tag="VQ547_000213"
     CDS             complement(52052..52294)
                     /locus_tag="VQ547_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2542142.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(52295..52927)
                     /locus_tag="VQ547_000214"
     CDS             complement(52295..52927)
                     /locus_tag="VQ547_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542143.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52941..53936)
                     /locus_tag="VQ547_000215"
     CDS             complement(52941..53936)
                     /locus_tag="VQ547_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2542144.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53933..54631)
                     /locus_tag="VQ547_000216"
     CDS             complement(53933..54631)
                     /locus_tag="VQ547_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2542145.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(54709..55719)
                     /locus_tag="VQ547_000217"
     CDS             complement(54709..55719)
                     /locus_tag="VQ547_000217"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2542146.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(55703..56710)
                     /locus_tag="VQ547_000218"
     CDS             complement(55703..56710)
                     /locus_tag="VQ547_000218"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2542147.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ547_000219"
     CDS             complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ547_000219"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2542148.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ547_000220"
     CDS             complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ547_000220"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2542149.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(58632..58961)
                     /locus_tag="VQ547_000221"
     CDS             complement(58632..58961)
                     /locus_tag="VQ547_000221"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2542150.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            59623..59959
                     /locus_tag="VQ547_000222"
                     /pseudo
     CDS             59623..59959
                     /locus_tag="VQ547_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            59859..60446
                     /locus_tag="VQ547_000223"
     CDS             59859..60446
                     /locus_tag="VQ547_000223"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542151.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            60489..61721
                     /locus_tag="VQ547_000224"
     CDS             60489..61721
                     /locus_tag="VQ547_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2542152.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ547_000225"
     CDS             complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ547_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2542153.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(62893..63582)
                     /locus_tag="VQ547_000226"
     CDS             complement(62893..63582)
                     /locus_tag="VQ547_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542154.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ547_000227"
     CDS             complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ547_000227"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2542155.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ547_000228"
     CDS             complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ547_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2542156.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(66501..67658)
                     /locus_tag="VQ547_000229"
     CDS             complement(66501..67658)
                     /locus_tag="VQ547_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2542157.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(67743..68123)
                     /gene="rnpB"
                     /locus_tag="VQ547_000230"
     ncRNA           complement(67743..68123)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ547_000230"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ547_000231"
     CDS             complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ547_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2542158.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(68543..69070)
                     /locus_tag="VQ547_000232"
     CDS             complement(68543..69070)
                     /locus_tag="VQ547_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2542159.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            69136..69732
                     /gene="recU"
                     /locus_tag="VQ547_000233"
     CDS             69136..69732
                     /gene="recU"
                     /locus_tag="VQ547_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2542160.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            69729..71888
                     /locus_tag="VQ547_000234"
     CDS             69729..71888
                     /locus_tag="VQ547_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2542161.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(72055..77358)
                     /locus_tag="VQ547_000235"
     CDS             complement(72055..77358)
                     /locus_tag="VQ547_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2542162.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(77659..79641)
                     /locus_tag="VQ547_000236"
     CDS             complement(77659..79641)
                     /locus_tag="VQ547_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542163.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        23234 a        18152 c        14752 g        23630 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttaga ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg
      541 ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt
      601 tagctggaag aatgatcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg
      661 ccaaagcatg ccctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaat
      721 aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc cgaaccctgt
      781 tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat ttctgaaatt
      841 aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg tgctctaaaa
      901 tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct
      961 tatagtttgt cttttttcta tcttccatta tatcatactt tttcagtcta tggtagctct
     1021 ctttaaaagg caccgatact gccgccacct ccgcctccag agaagccacc accagaactt
     1081 ccacttccag aagatacaga gtaggtgctt gctgtatttg cgacactagc ataatggctc
     1141 atttgcgcgc ttgaatgata aaacagactg tgccagccat aagctacata gagattgata
     1201 tctggatttt ccacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag
     1261 ccaaataagg tcgcatagac caagaggcga ttccagacca caatactttc cagttcagcc
     1321 tgatccaatc gtgcaatctc acgcaacata ttttcaaaac tggtccagag atagtagacc
     1381 tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag
     1441 aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca
     1501 tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcag gatagtcaag
     1561 gcacccatac ccacttgcaa ggccttttcc ccaccagtta aaggacgata ataatctggg
     1621 agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa tacctcttca
     1681 aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga aactttggct
     1741 ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag agtttcttct
     1801 tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa accatcttct
     1861 tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt cccacggtct
     1921 atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc agctcccttg
     1981 accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa aaccataggc
     2041 tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac tgaaggagtg
     2101 gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat agaaaggatc
     2161 gaagggagga cccaagtaac aagttgttta ctctgatctt tttctctaac aatcgagtct
     2221 tctatcttat taaactcttc taaacgattc cctttcaatc cctgatccct agcgctagca
     2281 aaatcggtcc gaggccaata ggcatgcaac tcaactccac gcttagccgg aagattgtct
     2341 aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa aagtttccct
     2401 gtatggaaaa agagtttttc agctcccttg tctcccctta catgaaattc aaacttttca
     2461 atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaagg
     2521 aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct
     2581 ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct
     2641 gctagttctg caccgttttt cgcggcctga acctttggat gagggtcaat gtcaaacccg
     2701 ctaggcatct taccagcacg tccaagtccc acgatttgtc ccttaaagtc ctcctcaaac
     2761 tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata caaatcccct
     2821 tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag
     2881 cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta
     2941 tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc
     3001 gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat
     3061 atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc
     3121 cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact ggacccagga
     3181 tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga
     3241 tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa aaacctttgg ttgttaaaac
     3301 caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg
     3361 tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt actacactag
     3421 cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat ctttggatga
     3481 ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctctacgact tgattgcaca
     3541 aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc gacaagctct
     3601 tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga ctgctgaagc
     3661 tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg gggaagaaga
     3721 tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa tcaatgccag
     3781 cattgaaacc atttcaaaag atgaccaagt tgccttgatg gatcgtatga tcaaggaaca
     3841 acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagtcgctaa
     3901 aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc
     3961 tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct tccgtactgc
     4021 tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct gggttctcaa
     4081 tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg ttatctacta
     4141 tggaactgcc caagctttcg gtatcaacct tgaccgtaca ctagctgcta tcttcatcgt
     4201 ttcaatcaat accggtgcct acatgactga aattgtccgt ggtggtatcc tggcagttga
     4261 caagggacaa tttgaagctg cgactgctct tggtatgact cataaccaaa ccatgtgtaa
     4321 gattgtccta cctcaggttg tccgcaatat cctaccagca actggtaatg aatttgtcat
     4381 caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg
     4441 aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat
     4501 ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc gcagaatgga
     4561 catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca
     4621 caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa
     4681 gacatttctc tcactgtcca caagggagaa gttatttcta tcatcggaag ctctggaagt
     4741 gggaaatcaa ccttcctacg ctccattaac ctacttgaaa cgccaactga tggacaaatc
     4801 ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag
     4861 ttagggatgg ttttccaatc ctttaacctc tttgaaaatc tcaacgttct tgaaaacaca
     4921 atcgtcgctc agacaactgt ccttaaacgc gaacgcacag aagctgaaga aattgccaaa
     4981 gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagcgagacc caaacaactc
     5041 tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tttcaatgaa tcctgacgcc
     5101 attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga ggtcctcaaa
     5161 atcatgcaag atctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa
     5221 tttgcccgtg atgtctctca ccgtgttatc tttatggata agggtgtgat tgctgaagaa
     5281 ggtaaaccag aagacctctt cactaatcct aaagaagacc gtacaaaaga atttcttcaa
     5341 cgttatctca tactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc
     5401 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
     5461 atcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc tcaaaatgaa
     5521 aaggcagatt ctctatctct actacttgaa ggtcaagaat ccaccgttat ccaaagatta
     5581 atcttcaaat ttttcatgat ttttttcata gaaatcaatt aagcctaggg ctgtttcaaa
     5641 tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca tttcacgcgc
     5701 attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc agccaacaac
     5761 tgattctact ttttcaaagt ttgacttagc catgtttttc tcctattttc ttctttataa
     5821 tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata ttcaacgaaa
     5881 ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata ggttttgcta
     5941 gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc ttaaggtgca
     6001 aaattattca agttcttaaa aaatgcttct ctatttccgt aagatagctt atttcttcga
     6061 tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttctc tagctcaaaa
     6121 actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta tatccttcaa
     6181 attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg attatctaaa
     6241 ccatccttaa tagagatgac aagacagata agctcagtta attacttata tatcttttta
     6301 atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa tgaaaatcaa
     6361 agagcaaact aggaagctag ccgcaaattg ctcaaaacac tgttttgagg tttcagatag
     6421 agctaacgtg gtttgaagag attttcgaag agtattaaag acagtatgac tatgcttgtc
     6481 aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata agtgctataa
     6541 tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg tcccctttct
     6601 tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt tttttattag
     6661 tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat aagctggatc
     6721 aaaaccttcc attctacgga tcaaacctgc ataatcatgc ttatctgcca aagcgatccc
     6781 aatcaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac gtgtgatatc
     6841 atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac gctgtgggaa
     6901 attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt ccatttctgg
     6961 catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt tccccttaat
     7021 atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt ctgcgactat
     7081 cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat cgacacctac
     7141 caaagtttga atatgttgac gagttgcttc ataggtcaac tgacctacct tttgcacagc
     7201 aatcccatcc gcaaatttat caatttcctt gagtttgact ggacctccag cctcaaaggc
     7261 agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct ctggacttgt
     7321 ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag gaaccaagac
     7381 agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag caactgttcc
     7441 ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat tttcagagac
     7501 tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta gtttaatagt
     7561 tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg tagtaatagg
     7621 cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc cctgcgcatg
     7681 atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga gctgggaaat
     7741 ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt cttttttcaa
     7801 ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg gagtattcac
     7861 aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta acatataaaa
     7921 cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca tctccgaaaa
     7981 cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct ttaggaagtt
     8041 cataacgatt tgtggaaatc caatcatata accattctac caaactttct tcactatcat
     8101 tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc aaatccaacg
     8161 tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt tgatctgtca
     8221 attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta tcagtttcat
     8281 cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa cccctaaata
     8341 agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa
     8401 cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaacc gccatctatc
     8461 gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc gaatctaaca
     8521 gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta tttctcaaaa
     8581 tccatttcgc tatataacga gcagatttag tcgcaccagc tctctcaaac ggagaatgaa
     8641 tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca aaggtcatat
     8701 gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca ttttcatcat
     8761 acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta attacattat
     8821 acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat aaaatcatct
     8881 ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc gtttttacca
     8941 acaaatggca ttgctttacg caattctgca ccaacttttt caatttcaag gttagctgct
     9001 tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac aaagtcattt
     9061 gcaaatttac cattttggat gtctgccaag acagccttca tattttcttt aacttgttca
     9121 gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga aatagattga
     9181 cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat ttcgtgaaga
     9241 acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc gaaacctgct
     9301 tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa atcttcttca
     9361 gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac acctttacac
     9421 cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc ataaagagct
     9481 ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcccggtcc tttaggagca
     9541 cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat gttgaaacca
     9601 tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc ttcgtacaat
     9661 tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt agtagcttct
     9721 actactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt acctggacgt
     9781 acaccgataa taacgtcacg acctgaatca cgcaagtttt gagcatgcgc atgtccttgt
     9841 gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt aacatctttt
     9901 tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat tgccttttag
     9961 gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt gcacccgttc
    10021 gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg ctcttttctg
    10081 catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctaccact gttgcacgga
    10141 aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac atcttaacca
    10201 aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa
    10261 tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca acatcaataa
    10321 taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg ctttcaatat
    10381 taacctgacg acgagatagg acacctgtaa agcgattgag gactcctgaa cgattttgta
    10441 gttttgctgt taacattcta cgcatggaac tgcaccccca acatctcatg attactctta
    10501 ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc aattagcata
    10561 ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt gtcaaactta
    10621 tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt atcaaagacc
    10681 gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat tccaagtgaa
    10741 tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat agccaactcc
    10801 tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt atctgggtta
    10861 gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa accacctgaa
    10921 gtcactaact gacgctcatt ttggtaggga taatactgag ctgtccacat ttggtgttga
    10981 ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg ttcaataact
    11041 gcttgcggtt gaaccacacg ctctttcttg tcataagaac gaacacgatt cttgtcttta
    11101 gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc tagcaacatt
    11161 tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat cttgccaatc
    11221 tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt cttaggattc
    11281 cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc ttccgtcatg
    11341 gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag tgggtgactc
    11401 gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata gcgttctgca
    11461 aattcattta gttccgtagc agcctcagca taactaattc caccaccagc taacaagact
    11521 ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc attcggctca
    11581 agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc tgtttctaaa
    11641 gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt agttgcgata
    11701 tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg gtaattgtac
    11761 ttagtgattg gcatggtaat tcctacgatg tctgcctcct gaaaggcatc cttcccaatc
    11821 cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct catagcatcc
    11881 gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc aacacccaac
    11941 tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc atggcgccct
    12001 agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa aaccgcacca
    12061 ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa aactaggtcc
    12121 gaccccgtct taggagattc taaactgatt ttctccattg ttcccctttc tttcctctta
    12181 aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa agaagaaatt
    12241 ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt attaaaaaga
    12301 taccgatttc atttactaaa aaagaaaaaa gaactgattt ctcagtcctt cattaatctt
    12361 attccacact aaataggtat gggtaaacag gttgttgacc ttggtgaatc tcgacttcaa
    12421 cgtcttcgaa ttcttctacg atttcttgag cgatttcatt ggcaagttct tcgcttccgt
    12481 cttcaccgac atagaaggtt acgatttcac tatcttcatc caacatatgt ttcaaggttt
    12541 cagtcaatgt ttggtgcata tcagggtttg acacaagaat ttttccatcc accataccta
    12601 gattatcgtt ttcatggatt tctaagccat cgatcgttgt atcacgcacg gctgttgtga
    12661 cgcttccgct aacgacatcg ctaagagcag ctgtcatacg ctcttggttt tcttcaatgg
    12721 acttgcttgg atcaaaggca agaagacttg tcataccttg aggaagagtg cgagcctcta
    12781 ccactactgc tggttgctcc aaaacttctg ccgcagattg agctgccatg aagatgttct
    12841 tgttgtttgg caagaagatg atgttacggg cattgacctg ttcaacagcc ttgataaagt
    12901 cttctgttga agggttcatg gtttgaccgc cttcgataac ataatccacg ccttgagaac
    12961 agaagatatc tgctagacct ttaccagcca ccacagcaat caaagcatac tctttttctt
    13021 cagccgactt gataacttga gtagcttctt tctcaacctg tgcttcgtgt tggttacgca
    13081 tattgtcaac ttttaccttg accaagctac catatttgag accttcttgc ataacaagtc
    13141 ctggatcttc tgtatgaaca tggactttga caatttcatc atcgttaaca acgaggagag
    13201 aatccccaag ctcatccaag tagttacgga attcatcgta gtcaaaatct ttagcatagg
    13261 ttggaccttg cttaagagct accatgattt cagtacagta accaaacgtg atgtcctcag
    13321 tcgctacgtg accagctaca gacttatgat gctctacatt gatcatctca ctcatgttgg
    13381 caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc agtaagggct gaaaggaaac
    13441 cttcgtagat gaagaccaat ccttgaccac ctgagtccac aacgccaact tctttcaata
    13501 ctggaagcat gtctggtgtt ttagctagag ctgttttagc accttccaag gctgcgcgca
    13561 tgacttcaac agtgtcatct gtttgctcag cttttttctt agcaccgata gcagctccac
    13621 gagaaactgt caaaatcgtt ccttcaacag gtttcatcac tgccttatag gcaacttcca
    13681 cacctgattg gaaggccaga gccaagtctt gacctgttaa ctcgtcttta tccttgatag
    13741 cttgggaaaa tccacggaaa agctgagacg taatcactcc tgagttccca cgcgcaccca
    13801 tcaaaagccc tttggcaaga atgctcgcta cttctccaac tgtagaagct ggcttgtctg
    13861 caacttcttt agcaccattt tcaatggtca ttcccatatt tgtcccagta tctccatctg
    13921 gaactggaaa gacgtttaat gaattgacat attcagcttg cttattcaag cgagttgatg
    13981 cagcctgcac catttcttga aataagctag tagtaatttt tgacacggtt attctcctac
    14041 aactttgata ttttgaatgt agacatttac agtctgagca gtaattccaa gctggttttc
    14101 caagctaaag gcaacacgct cttgaatgtt ttttgacact tcactaatct ttgttccgta
    14161 gcttaacacg gtatatacat caactgcaat actgccatct tcggctgcct ttacgacgac
    14221 acctttagaa taattttcct tacctagcag ggcttggaaa ttatctttga gggcattttt
    14281 actagccata ccgaccacac caaaaatctc agttgctgct ccacctacga cggttgcaat
    14341 cacttcatct gttagttcga tttgaccatc ttttgtatta atttttacag tcatcctttt
    14401 tacctcaact agttgatact ctattttatc atatttcagc ccaagtgtaa aagcagaatg
    14461 atgtatcagc ggatatttac tctatttttc aaacgatgtt atacccacaa taaaagaaaa
    14521 aagaccctaa ggtctccttt gcttttatta ttaaacgcgt tcaactttac ctgatttcaa
    14581 agcacgagct gaagcccaaa cttttttagg tttaccatcg ataagaacag taactttttg
    14641 aaggtttggt tttacggcac gttttgtttg gttcatcgcg tgtgaacggt tgtttcctga
    14701 tacagtctta cgacctgtaa agtaacatac tttagccatt gtgttttcct cctattagat
    14761 ctaatatagc ggatgtgcta gcaccacata ccgtactatg ttatcacact ttcttgtttt
    14821 ttgcaaggga attggaagat tttttatttg tgtcttaaat caggtcttgc gtgacatttt
    14881 ctgctctcca catgccatcg ttgattaaca gaacaccaga attaaaatta tgtgtataaa
    14941 aatcatctct aactgcagct aagggtatag ccgtcaagtc caaatcccac agctcatcta
    15001 tcgattttct tacaacaata tctgaatcca aatacagtac acgagactcg cttacatact
    15061 ttggaataaa atacctaaaa aagccgcata tgaaagtccc tcaaagggga gacgataacc
    15121 tttcagaata ttactgtcaa tctaaacatt cacaatctca ctattcaaag tctctagtct
    15181 tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat aaaacttaag
    15241 attataatga tgaacacaaa gagattttat tgttgtttca actttatcca tataagcatt
    15301 atctgcacct aagacaatcg cttttttctc ttttttctct tctttcactt tttatctcat
    15361 ttctttttat tcccatcata tgtttctacg taaccattat tttcgcctat tcgttcgtaa
    15421 aaccatacca gtggagattt tagatgaagt cccattacgg tttacaattt ttacattacg
    15481 acacggagtt ttacaaatcg atttcatttg ccaaacgtag ttagtgaggc agttagctag
    15541 ttcgccaaat agcgactagc gtccaacaat ttggaacttt agttccaatt gttggtactg
    15601 agtcacatct tctcctctaa ctctacgtct ggatacttgt cagcaaacca gcggagggca
    15661 aagtcatttt caaagagaaa gactggttgg tcaaaacggt ctttggctaa gatattgcga
    15721 cttgacgaca tccgttcatc caagtcctca ggcttgatcc aacgaacggt ctttttaccc
    15781 attgggttca taactacttc tgcattgtac tcgccttcca tgcggtgttt aaagacttca
    15841 aactggagtt gacctacagc gcctagcatg tactcacctg tttggtaatt cttataaagc
    15901 tgaacggctc cttcttgcac caattgctca atccccttgt ggaaggattt ttgcttcata
    15961 acattcttag cagaaacttt catgaaaatt tcaggagtaa aggttggcag tggttcaaat
    16021 tcaaacttgt ttttaccaac tgtcaaggta tccccaactt gataagtacc ggtatcgtaa
    16081 accccgataa tatcacctgc cacggcattg atcacattct cacgactttc cgccataaac
    16141 tgggtaacat tagatagttt ggccccctta ccagtacgag ggagattgac actcatgcca
    16201 cgctcaaatt cgcctgatac gatacggaca aaggcaatac ggtcacggtg acgaggatcc
    16261 atgttggctt ggattttaaa gacaaagcct gagaaatcct tgtcataagg atccacaatt
    16321 tcaccgtctg ttttcttgtg accatgtggt tctggagcaa acttgaggaa gatttcaagg
    16381 aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa agacaggcgt caattctcca
    16441 gccagaatag cttcctctga aaactcattc ccagcttcat ttaaaagctc aatgtcatcc
    16501 ttgacttgct cgtagaaagg attgctacca aagagtttgt ccccgtcttc tagactggca
    16561 aaacgctcat cccctttgta aagctctaaa cgttggttat agaggtcata caagccctca
    16621 aaggctttcc ccatcccgat aggccagttc atagggtagc tagcaatgcc caagatttct
    16681 tccaattctt gcaagagatc caaaggctca cgaccgtcac ggtccagctt gttcataaag
    16741 gtaaaaactg gaatgccacg atgtttcaca acctcaaaca atttcttggt ttgagcctcg
    16801 atccccttgg cagagtccac gaccatgacc gcagcatcca ccgccatcaa ggtacgatag
    16861 gtatcttctg agaagtcctc gtgccctggc gtgtctaaga tattcacgcg cttgccgtcg
    16921 tagtcaaatt gcataacaga tgaagtaaca gaaatcccac gttgcttctc gatatccatc
    16981 cagtcagatt tagcaaaagt ccctgttttc ttccctttta ccgtaccagc ctcacgaatc
    17041 tcacccccaa agtagagtaa ctgctcagtg atggttgttt tccccgcgtc cgggtgggag
    17101 ataatggcaa aggtacgacg tttcttaatt tcttcttgaa tattcataag ttctctttct
    17161 ttgattctct atttttcttg tttcaatagc tgagaatgat ttttacattg gattttacca
    17221 ttcctttcaa cattccatta tatcggattt tagcattttt ttcaatttct atttcttttc
    17281 acttccccct cccttattta taggaaaata tggtaaaata gaacagacta aaaatcatca
    17341 tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag gtaacacacg ttgccaatct
    17401 ttcaaaatta agattctctg aagaagaaac tgctgccttt gcgaccacct tgtctaagat
    17461 tgttgacatg gttgaattgc tgggcgaagt tgacacaact ggtgtcgcac ctactacgac
    17521 tatggctgac cgcaagactg tactccgccc tgatgtggcc gaagaaggaa cagaccgtga
    17581 tcgcttgttt aaaaacgtac ctgaacaaga caactactat atcaaggtgc cagctatcct
    17641 agacgatgga ggagatgcct aatgactttt aacaataaaa ctattgaaga gttgcacaat
    17701 ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc aagcaacact tgaaaatatc
    17761 aagtctcgtg aggaagccct caattcattt gtcaccatcg ctgaggagca agctcttgtt
    17821 caagctaaag ccattgatga agctggaatt gatgctaaca atgtcctttc aggaattcca
    17881 cttgctgtta aggataacat ctctacagac ggtattctca caactgctgc ctcaaaaatg
    17941 ctctacaact atgagccaat ctttgatgcg acagctgttg ccaatgcaaa aaccaaaggc
    18001 atgattgtcg ttggaaagac caacatggac gaatttgcta tgggtggttc cggtgaaact
    18061 tcacactacg gagcaactaa aaacgcttgg gaccacagca aggttcctgg tgggtcatca
    18121 agtggttctg ccgcagctgt agcctcagga caagttcgct tgtcacttgg ttctgatact
    18181 ggtggttcca tccgccaacc tgctgccttc aacggaatcg ttggtctcaa accaacctac
    18241 ggaacagttt cacgtttcgg tctcattgcc tttggtagct cattagacca gattggacct
    18301 tttgctccta ctgttaagga aaatgccctc ttgctcaacg ctattgccag cgaagatact
    18361 aaagactcta cttctgctcc tgtccgcatc gccgacttta cttcaaaaat cggccaagac
    18421 attaagggca tgaaaattgc tttgcctaag gaatacctag gcgaaggaat tgatccagag
    18481 gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa aattgggtgc tatcgtcgaa
    18541 gaagtcagcc ttcctcactc taaatacggt gttgccgttt attacatcat cgcttcatca
    18601 gaagcttcat caaacttgca acgttttgac ggtatccgtt acggctaccg cgcagaagat
    18661 gcgactaatc ttgatgaaat ctatgtaaac agccgtagcc aaggttttgg tgaagaagtg
    18721 aagcgccgta tcatgctggg tactttcagt ctttcatcag gttactacga tgcctactac
    18781 aagaaggctg gacaggtccg tacacttatc attcaagatt tcgaaaaagt cttcgcggat
    18841 tacgatttga ttttgggtcc aactgctcca agtgttgcct atgacttgga ttctctcaac
    18901 catgacccag ttgccatgta cttagccgac ctcttgacca tacctgtaaa cttggcagga
    18961 ctgcctggaa tttcgattcc tgctggattc tctcaaggtc tacctgtcgg actccaattg
    19021 attggtccca agtactctga ggaaaccatt taccaagctg ctgctgcttt tgaagcaaca
    19081 acagactacc acaaacaaca acccgtgatt tttggaggtg acaactaatg aactttgaaa
    19141 cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa ttcaaaaatc ttctcaccta
    19201 cttctgccca ctttggaaat gaccaaaatg ccaacactaa cgtgattgac tggtctttcc
    19261 caggagttct accagttctc aataaagggg ttgttgatgc cggtatcaag gctgctcttg
    19321 ccctcaacat ggacctccac aaaaaaatgc actttgaccg caagaactac ttctaccctg
    19381 ataatcccaa agcctaccaa atttctcagt ttgatgagcc aatcggttat aacggctgga
    19441 ttgaagtcga gctagaagac ggtacgacca agaaaattgg tatcgaacgc gcccacttag
    19501 aggaagacgc tggtaaaaac acccacggta cagacggcta ctcttacgtt gaccttaacc
    19561 gccaaggggt acctttgatt gagattgtat ctgaagccga tatgcgttcg ccagaggagg
    19621 cctatgctta tctgacagcc ctcaaggaag ttatccagta cgctggcatt tctgacgtta
    19681 agatggaaga aggttctatg cgtgtggatg ccaacatctc ccttcgtcct tatggtcaag
    19741 agaaattcgg taccaagact gaattgaaga acctcaactc cttctcaaac gttcgtaaag
    19801 gtcttgaata cgaagtccaa cgccaggctg aaattcttcg ctcaggtggt caaatccgcc
    19861 aagaaacacg ccgttacgat gaagcgaata aagcaaccat cctcatgcgt gtcaaggaag
    19921 gggctgctga ctaccgctac ttcccagaac cagacctacc cctctttgaa atttctgacg
    19981 agtggattga ggaaatgcgg actgagttgc cagagtttcc aaaagaacgt cgtgcgcgtt
    20041 atgtatctga ccttggttta tcagactacg atgctagtca gttgactgct aataaagtca
    20101 cttctgactt ctttgaaaaa gctgttgccc taggtggtga tgccaaacaa gtctctaact
    20161 ggctccaagg ggaagtcgct cagttcttga atgctgaagg taaaacactg gaacaaatcg
    20221 aattgacacc agaaaacttg gttgaaatga ttgccatcat cgaagacggt actatttcat
    20281 ctaagattgc caagaaagtc tttgtccatc tagctaaaaa tggcggtggc gcgcgtgaat
    20341 acgtggaaaa agcaggtatg gttcaaattt cagatccagc tatcttgatc ccaatcatcc
    20401 accaagtctt tgccgataac gaagctgctg ttgccgactt caagtcaggc aaacgtaacg
    20461 ccgacaaagc ctttacagga ttccttatga aggcaaccaa aggccaagcc aacccacaag
    20521 ttgcccttaa actacttgca caggaattgg cgaagttgaa agaaaactag acagaacaaa
    20581 accagcccta aggttggttt tttcttctct accaactccc aataactatt ttggctttat
    20641 ttccagagta ttttatggta aaatgaagag taataatatt tattaaagag gtaaaaacat
    20701 gattgaagca agtaaattaa aagctggtat gacctttgaa acagctgacg gcaaattgat
    20761 tcgcgttttg gaagctagtc accacaagcc aggtaaagga aacacgatca tgcgtatgaa
    20821 attgcgtgat gtccgtactg gttctacatt tgacacaagc taccgtccag aggaaaaatt
    20881 tgaacaagct attatcgaga ctgtcccagc tcaatacttg tacaaaatgg atgacacagc
    20941 atacttcatg aatacagaaa cttacgacca gtacgaaatc cctgtagtca atgttgaaaa
    21001 cgaattgctt tacatccttg aaaactctga tgtgaaaatc caattctacg gaactgaagt
    21061 gatcggtgtc accgttccta ctactgttga gttgacagtt gctgaaactc aaccatctat
    21121 caaaggtgct actgttacag gttctggtaa accagcaacg atggaaactg gacttgtcgt
    21181 aaacgttcca gacttcatcg aagcaggaca aaaactcgtt atcaacactg cagaaggaac
    21241 ttacgtttct cgtgcctaat ctctagaaag aggtcattct atgggaattg aagaacaact
    21301 tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa
    21361 ggtagagggt gttcactctt tttcaaacag atcagtgtct gatacccttt caaaactttc
    21421 actcggccgt ggcgtttatc ttaaaaacgt ggacgaagaa ctcacagcag atatctatct
    21481 ctaccttgag tacggagtaa aagttcctaa ggtagcggtt gctatccaga aagctgtcaa
    21541 agatgccgtc cgtaatatgg ctgatgtaga actcgctgct atcaatattc acgttgcagg
    21601 tatcgtccca gataaaacac caaaaccaga attgaaagat ctatttgacg aggacttcct
    21661 caatgactag tccactatta gaatctagac gccaactccg taaatgcgct tttcaagctc
    21721 tcatgagcct tgagttcggt acgaatgtcg aaactgcttg tcgtttcgcc tatactcatg
    21781 atcgtgaaga tacggatgta caacttccag cctttttgat agacctcgtt tctggtgttc
    21841 aagctaaaaa ggaagaacta gataagcaaa tcactcagca tttaaaagta ggttggacca
    21901 ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt gggagttttt gaaatcactt
    21961 catttgacac tcctcagctg gttgctgtta atgaagctat cgagcttgca aaggacttct
    22021 ccgatcaaaa atctgcccgt tttatcaatg gactgctcag ccagtttgta acagaagaac
    22081 aataaaaaga aaaagtgttt gatagatatc aaacactttt tctttgcctc ccactatcta
    22141 aaaaaatgat aatagatata attgtaaaca aaaatccaga taggttttgc atgattgaga
    22201 aagttaaaaa aactatggca gagaatcgtt aatctcagat tgtcggtaga acgataaaca
    22261 agggcaaaaa agaaaccaat cagactataa tataataaac taattggatc tctgtgagat
    22321 agtatcaaat ggctaatccc aaagataagg cctgataaga tgacatctaa atagtacttt
    22381 gacttaggaa agaaggtatt cataaaatac cctctatcaa gagtctcctc aaaaacagga
    22441 ccgatgatta caagcaggac aaaagataag atagtcgata aaaaggttgg ttgtccattt
    22501 gaaagaacca cggtaaaata ctcatcatga atattcctat ggttaatcaa atgagcatag
    22561 cgtgcctaaa aattaccgag aatctgataa accacataag ttgcaaataa ggagaagaca
    22621 aatgaccagt cccagctctt tttctttttt aacctccaaa ttaatagaaa aggaaacttc
    22681 ccactaatcc cactgttaaa ataagagaat agacatcagc tcctaaccct aaaatgatcg
    22741 tcacatacaa tccaattgtt tgtggtaaat aggtagatag taaaataata agcaaaaata
    22801 ttccaaattg tcttagtttc tttgtgtttc tcatcgtact tttttgaaag attaccctgt
    22861 tcggaagccg tacttccaag catctatata agaattaagt gccccttgcc tcatataggg
    22921 agcaaattct ctataatata accatctact atatccatct tcccaaacag caagaccacc
    22981 tgaagtttgc tccaagtcct cagttgaaag aactgtaaat gtttctgtac ctgtcattgc
    23041 aagtaccttc ttaaaataga ttgttgtagg ctcacattta tagtatattt ctttttttgt
    23101 ctattttata gtctatctcc tcaactggca atttttcgac ctgaattgca tttttccata
    23161 aaaaatgaga cctttctagt ctcatttagt cattcttagt attttctaaa tcgttgatag
    23221 cgttcttcca gcaactcttc tagcggtttt tgtgaaagtc tagccagctc cgtttggagt
    23281 tcttttttga cactcttaat tagttcttta ctagaaagtc ctacttcaga aatcacctta
    23341 tccaccacgt ccatttctaa cagttcatgc gaagtgattt tcatcagttc tgctgcttcc
    23401 atggcgcgag taccgtcctt ccataaaatg gaagcaaagc cttctggact gagaatggca
    23461 tagatagaat tttccagcat ccagacacgg tccgcgacag ctagagccag agccccgcct
    23521 gaaccacctt caccgataat aatggcgata ataggaactt tcaggtcact catttccatg
    23581 agattgcgag cgatagcttc cccttgacca cgttcttccg ctccgacacc aggataagca
    23641 cctgctgtat tgataaaggt cacaactgga cggccaaatt tctcagcctg tttcatcaac
    23701 cgcagtgcct ttcggtagcc ttctggatgt ggttggccaa aattccgttt gaggttgtct
    23761 tgcaaactct tgcctttttg gataccaacc actgttacag cttggtctcc aagccaacca
    23821 ataccaccaa caactgcacc atcatcacga aaagaacggt caccatgtaa ttggataaat
    23881 tcatcaaaaa tgcctgtcgc aaagtccaag gttgtcaagc gactctgctc acgcgcttct
    23941 ctgactattt ttgcaatatt catctaggac tccctccatg caatctgact aggctagcaa
    24001 tcgtatctgg taagtctctt cttttgacaa tagcatccac aaagccatgt tctaatagga
    24061 attctgcctt ttggaaatcc tcaggcaagc tttcacgaac cgtattttca atcacacgac
    24121 gcccagcaaa accaaccaag ctctgtggtt cagccagaat gatatcgcct tccatagcga
    24181 aagaagctgt cacaccacca gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag
    24241 catttgaatg gcgtttaacc gctgcagaga tcttagccat ctgcatgaga ctcatgattc
    24301 cttcctgcat acgggctcca ccagaggctg tgaataggac aactggtaat ttttcgacag
    24361 tcgcatactc aaacaaacga gtgatttttt cacctacaac cgtacccata gaagccatga
    24421 taaaattaga atccataatc ccaagagcca cagtctgacc tttaataaga gcagttcctg
    24481 tcacaacggc ttcatgcaga cctgtttttt cacgcataga tgccagtttc ttttggtaac
    24541 cagggaaatg caagggatcc ttgctttcaa tccctgtaaa caattctttg aaggttccca
    24601 tatcaatcgt caaagccaag cgttcttggg cagaaatacg aaaggtatag ctacagtgcg
    24661 gacagatacg ttcacttccc agatccttct gatagatggt atgcttacag cctggacact
    24721 gggaaaataa ttcatctgga acctctggct tagcttgagg tttttcccta accgaacgat
    24781 tgggattgat tcgaatatac ttatcttttt tactaaatag agccattgat tccccttttc
    24841 ggtttaaact cttaaagtca ttttattctt tttcttgata tttaggtaag aaggtttcca
    24901 tcaagaagga agtatcataa tccccagcaa tgacattgcg atctgaaatg agatcaagct
    24961 ggaaatctgc attggtctgc actccttcaa tctctaattc atagagggca cgttgcattt
    25021 tcatcaaggc gtcaaaacga ttttcgccgt gtactatgat tttggcaatc atactatcat
    25081 aataaggcgg aatggtataa cctggataaa ctgctgaatc cacgcgcaag ccaactccac
    25141 cacttggcag atagagatta gtaatcttac ctggacttgg agcaaagtta aaggctgggt
    25201 tttctgcatt gatacgacac tcgatggcat gaccgcgtag gacaatatct tcttgcttaa
    25261 cagacaaagg ctgacctgcc gcaatgcaaa tctgttcctt aacgatatca acacctgaaa
    25321 caaactctgt tactggatgt tctacctgaa cacgagtatt catctccatg aaatagaaat
    25381 tgctacttgc ttcatcaaga agaaattcaa tggttcctgc attctcatag ccaacaaact
    25441 ctgccgctcg aacagcagca gcacctattt catgacgcag cgtttttccg attgcaatcg
    25501 agggactttc ttccaaaacc ttttggttat tcctttgaag agaacaatcc cgttcaccca
    25561 agtgaatcac atgtccatgc tcatcaccta ggatttgaac ctcaatgtgc cgagctggat
    25621 agataacccg ttctatgtac atggcaccat tgccataatt ggccttggcc tcactagagg
    25681 cagtttcaaa ggcagaaacg aggtcatctg gtttttcaac cttacgaatc cctttaccac
    25741 ctccacctgc tgaagccttg agcataacag gatagccaat tttttcagca acaatcaaag
    25801 cttcttcaga gttatgcact tctccatctg aacctggtat aacaggcaca cctgctttaa
    25861 tcatctgagc acgcgcattg atcttatccc ccatcatatc cataacatga ccagatggac
    25921 cgataaactt gatacctact tcttcacaca tggtcgcaaa tttggaattt tcactgagaa
    25981 atccaaaacc agggtgaata gcttctgcct cagtcaagac tgcagctgat agaactgcat
    26041 taatattgag ataagactct gttgccttgc caggaccaat acaaactgct tcatctgcca
    26101 acagcgtatg aagagcttcc ttatcagcag ttgaataaac cgctaccgtc gcaatcccca
    26161 attcacgtgc cgcacggata atacgaaccg caatttcacc acgattggca attaaaattt
    26221 ttcgaaacat ggagaacctc cttagttccc aattgcaaaa gtaagggtac cactggctgc
    26281 aagcttgcca tccacttcag cctttgcttc aaccacagct atggtgccac gacgttttac
    26341 aaaagtcgct gtcataacca attggtcgcc tggtacaact tgcttcttga acttaacctt
    26401 atccatacca gcgtaaaaga ccagttttcc tttattttca ggttttgata actccaacac
    26461 accagcagtt tgcgccaagg cttccataat cagaacacct ggcataactg ggtattgagg
    26521 aaagtggccg ttaaagaaag gctcgttgat ggtcacattt ttgatagcaa caatggtatc
    26581 ctcgctcacc tccaagacac ggtccactag aagcatagga taacggtggg gaagggcttc
    26641 tttgattcct tgaatatcga tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt
    26701 tcttcgttag agacgagaat ttccgttacc acaccatcct taggagctgg gatttcattc
    26761 atgactttca tggcttcgat aattaccaat gtttgacctt ttttgacact atcaccaact
    26821 gtaacgaagg caggtttatc tggtccagca gccaagtaaa ccactccaac aagtggactc
    26881 tctacaagat ttccctcact agccacactt gcttcagctg gagctggaac ttcttctgct
    26941 acagtctctg ctggagcaga tgtaggagct actggactcg gtgttgctag aacgggtgct
    27001 ggagcgactt gagttgcaac ttcaggcaca ggtctcgctt cattcttgct aaactgcaac
    27061 tcatccgtcc catttttata agaaaattct ctcaaacttg actggtcaaa ttgagtcatc
    27121 aagtctttaa tatcgtttaa attcatactt atctattctc ccaacgtttg aaagcaagaa
    27181 ctgcattgtg gcctccaaaa ccaaaagtat ttgaaatagc gtatggaatt tctttctcca
    27241 agccttgtcc ataaacgaca ttagcttcga tataatctga tacttcactt gtcccagctg
    27301 tcattggtac aaagttatga cgcatagctt cgatggtgac gatagcttct actgcacccg
    27361 cagcccccag caaatgtcct gtaaaagact tggttgatga tacaggtact tccttaccaa
    27421 gaacagctac gatagcacca ctttctcctt tttcattggc aggagttgac gttccgtgag
    27481 cattgacata ggctacttgc tctggagaaa tctcagcttc ttccaaggct agtttgatgg
    27541 ccttgatagc tccctgacct tctggatgtg gagaagtcat gtggtaggca tcacaagtat
    27601 ttccgtaacc aaccacttca gccaggatag tagctccacg tttttcagcg tgttcaagac
    27661 tttctagaac caacatccct gaaccttcac ccataacaaa cccattgcga tccttatcaa
    27721 atgggatcga agcacgagtt ggatcctctg tagtagagag agctgttaag gcttggaaac
    27781 cagcgatggc aaaaggtgtg atagaagctt ctgttcctcc caccaacatc acatcttgga
    27841 aaccaaactt aatggagcgg aaggcatccc caatcgcatc atttgatgaa gagcaggcag
    27901 tattgataga tttacaaaca ccgtttgcac caaaacgcat ggctacattc ccagaagcca
    27961 tatttggtaa agcttttgga agagtcattg gtttgacacg tttgggtcct ttttcatgaa
    28021 ggcgaagtac ctgatcttca atttccttga ttccaccaat accagatgca acgataacac
    28081 caaaacgatc cctattaaga gcctctacat caagattggc atgatttaca gcctcttggg
    28141 ctgcatacaa ggcatataaa gaatagttat caaaacggtt ggtatctttt tttacaaagt
    28201 atttatcgaa cggaaaatct tggatttctg ccgcattatg cacatcaaag tcactatgat
    28261 caaattttgt aatgccacca atgccgattt tcccagttgc taaactattc caaaattctt
    28321 ctggtgtatt tccgattgga gatgttactc cataacctgt taccactact cgatttagtt
    28381 tcattctttt cacctctagc tttcgctaca tacttaagcc accatcaatg gcaatcactt
    28441 gaccagttag ataatcttgg cctgctaaaa atactgtcaa atctgcaacc tgctctgcct
    28501 gcccaaattc tttcatcgga atctgagcta gtgtagcttc cttaatctta tctgataaga
    28561 tagctgtcat atcagactca atcattcctg gagcaatcac attgactcgt atattccgac
    28621 tagcgacctc gcgtgccaca gacttggtaa agccaatcaa gccagcctta gaagcagcat
    28681 agttagcttg accaatattc cccatcaaac caacaacact agacatatta atgatagcac
    28741 cttctctggc tttcatcatc ggtttcaaga ctgattgtgt catattaaag gcaccagtca
    28801 gattgacctt gagcactttt tcaaaatctg cttctgtcat cttgagcata agagtatctt
    28861 gggtaatccc tgcattgttg accaaaacat ctactgaacc cagttctgca atagcttgat
    28921 caatcatacg cttagcgtct gcaaaatctg atacatctcc tgaaatggga accaccttga
    28981 taccatagtt tgaaaactca gcgagcaatt cttctgagat tgccccacga ctgtttaaga
    29041 caatgttggc tcctgcttga gcaaacttgt gggcgatggc aagaccaatt ccacgactcg
    29101 aacctgtaat aaagatattt ttatgttcta gtttcatttt tttcctttca aaacttctac
    29161 ttattttagt ctatttttct aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta
    29221 agtgagcagt ttgatcaatt tttttaacaa aacctgacaa gactttcccc ggtccaatct
    29281 cgataaagtt gcttatgcct gcttcttgca tgaccccaat actttcatag aaacgaacgg
    29341 gttccttgac ctgacgcgtc aagagctgag caatgtcctc tttttgcatc acagcagctt
    29401 ctgtattgcc gactagggga caagtaaaat ctgaaaaact tacctgagct agagtttcag
    29461 ctagtttctg gctagcaggc tcaaggagag cggtgtgaaa gggacctgac accttaagag
    29521 gaatcaagcg tttggcacct gcttcttgca aaagttcaac cgctcgatca actgcaacca
    29581 cttctccagc aatgacgatt tgtgcaggtg tgttatagtt ggctggagta accactccaa
    29641 gttcagaagc tttttgacag gcttcttcaa tgacctctac tggcgtattg agaactgcta
    29701 ccatcttgcc agagtcagca ggagccgctt cttccatata ggctccacgc ttagctacca
    29761 aggcaaccgc atcttcaaaa tccaaggcgc cgcttgccac caaggcagag tattctccaa
    29821 gagacaaacc agcaaccata tcaggctgat agcccttttc ttgcaataaa cggtagatag
    29881 caaccgaagt cgctagaatg gctggttgcg tatagcgggt ctgattgagt ttgtcttctt
    29941 ccgtatcgat gagataacgt aaatcataac cgagcacctg actcgctcga tcaatcgttt
    30001 ctttaacaat cggatactga tcatagaaat cccgtcccat ccctagatac tgggcacctt
    30061 gaccagcaaa taaaaaggct gttttagtca tttcttacaa ctcctgccca gcgagaggct
    30121 tcttcttgaa ttttcttagc ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt
    30181 tcttctttag aaacaagccc tgcgatttga cctgccatga cagagccacc ctccacatca
    30241 ccgtgaacaa ctgctttggc tagggcacct gctcccattt gttcaaagat ttctaaatca
    30301 ggatcttcct gcttaaaggc atctttttca gccagttcaa aatctctagt caactgattt
    30361 ttaatagcac gaacagcatg accaaagtgc tgagctgaaa tcgtagtatc aatatccctt
    30421 gcttttaaaa ttttctcttt gtagtttgga tgggcattcg actcttttgc aactacaaac
    30481 cgtgtcccca cctgtacagc ctctgcacct agcataaagc cagccgcagc accttcacca
    30541 tccgcaattc ctcctgcagc aataacagga atagatatag ctgtggctac ctgtcgcacc
    30601 aaggtcatgg ttgttaattt accgatatgc cccccagctt ccattccttc tgcaataaca
    30661 gcgtctgcac cgattttttc catgcgttta gctaaagcga cactaggaac aacaggaata
    30721 acgattatcc cagcttcatg gaaacgttcc atatacttgc ttggatttcc tgctcctgtt
    30781 gtgacaactt taacaccttc ttcaataacg agatccacga tatcttccac aaagggagat
    30841 aagagcatga tgttgacccc aaagggttta tcagtcaatg atttgatttt atcaatattg
    30901 gccttgacaa cttctttcgg ggcatttccc ccaccgataa ttcctaatcc tccagccttg
    30961 gaaacagccc ctgccaaatc accatcagca acccaggcca tccctccttg gaaaatagga
    31021 tagtcaatct tcaataattc tgtaatacgc gttttcatag tgcctccaac cttccttgct
    31081 tacgtaatag ttcgatttca ccataatttg acagtcaaac tattacctaa acaagaggga
    31141 gtgggtttct ccctactcct tctactaata ttctgcttat tttgcttgct cttcaacgta
    31201 agcaaccaag tcaccaactg ttttcaagtc attttctgct tcgatttgga tatcaaaagc
    31261 atcttcgatt tctgagatta cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa
    31321 agttgattca agtgttactt ctgatgcgtc ttttccaagt tcttcaacga taatttcttg
    31381 tactttttca aatactgcca tgataggact cctttaaaat aaatagtttt tttataacaa
    31441 tgtgttcacc acatgattac ctaaattgta agaatgagcg tgccccaggt caagcctcca
    31501 ccgaagcctg atagaagaac agtttggcta ccatctaaag ggatgagacc ttgttctaca
    31561 cactctgaaa gtaaaatcgg gatactggct gcactggtat tgccatattc catcatatta
    31621 gctggaagtt tggctcggtc aacaccaatt tttctagcca tcttatccaa aatacggtta
    31681 ttggcttgat gaagtagcag ataatccaag tctgtcacct ctataggaga ttcatcaata
    31741 gtctgcttga tagacttggc tacatctcga atggcaaaat caaagactgt gcgtccatcc
    31801 atcttcaaaa atgaatctgc actttcttga tctgaaaatg gagaatgcaa acctgaatgc
    31861 ccataagtta aacactcgct gcgacttcca tcgctattga gactctcagc taagaaatgc
    31921 tcttgctcgc tagcttctaa caagacacca ccagcaccat ctccaaacaa cacagctgtt
    31981 gatcgatccg accaatcgac tgccttagag agggtttcac taccaatcac caagcctttt
    32041 tgaaagcgac cagaagcgat aaacttttca gcagttgaaa gagcaaatac aaatccactg
    32101 caagccgcgg ttaagtcaaa agcaaaggct ttattagcac caatattagc ttgaacacga
    32161 gcagctgtag agggcatcat cgaatctgga gtaatggtag ctaggatgat aaaatccagt
    32221 tcttctcctg ttattccagc ttttgccatc agtttcttag caacctctgt agccaaatca
    32281 ctggtagatt ctgttcttga aatatgcctt tgtcgtattc ccgttcgact tgaaatccac
    32341 tcatcattgg tatccataat ctgagccaag tcgtgatttg taaccacttg ctctggcaca
    32401 taatgagcaa cctgacttat ttttgcaaaa gccattattt caaatcctcc aaaaattggt
    32461 aaagattagt caaaccttta cccatgacag caatttcttc ctcgctcatg ccatcaataa
    32521 ttttttctac catggccttg tggaagcgtt tatgcagtct atgaatcaag cgacccttct
    32581 ttgtcaaatg cagatgcacc acacgacgat cctgttctga ccgaactcgc tcaatgtagc
    32641 ccttacgctc taaattgttc aaacttgtcg taacagttcc aagagttacc atcaactctt
    32701 ttgacacttg acttggagtc acatctggag ccttaccgat gacatcaatc gtatgcattt
    32761 ctttgatgga gatatcctta aaacgactac ctctcaagtt cacttcctca attacaagga
    32821 cattgttaaa tatagatgtt aaatattcat tgattcgttg gtagtccatt tttcatatcc
    32881 ctccttcttc aaaaaacttt tacaatcaaa acatttgaca gaaagaatta tatcaaaatt
    32941 caaagaatga tgcaagtatt ttttattttc ctgtaaattt aggtcttctt ctctccgaat
    33001 gagctcgcac tccttctttg aaatcctctg tttgagctaa ggatttctgt aggttcagtt
    33061 ctaaagtagc gtaaccctgc cagtctttaa attggctctc ccaaaccaac ttcttaatgg
    33121 cagcatagga attacttgaa gcacgtctta attttttaag aagctgttct ctcgtctttt
    33181 caagtttttc agcttcagaa acgcggtaaa ccaaccccca ttctagggct ttttctgccg
    33241 ttaaagcctc tcctgtcata gctaattgag cagcacgcgt cacaccgata ctgcggctca
    33301 agagatgaat tccccctgca tctggagcca aaccaacacc aacaaaggct tggataaact
    33361 tagccttatc cgtcgccaaa cagaaatctg ccgcaacagc catattcgct gcggcacctg
    33421 caacagcacc gtcaacttcc attaaaacag gtttggctat ttgcttgatt ttataagaaa
    33481 tcgtattgac caactctgcg atttttgtca atgatggaat atcatcctca tccactgccc
    33541 gcttcatctc taccaaatct cccccaactg agaagacctt tccattggca ttgattaaga
    33601 taaaatgcac agctggattt tcttctgcca aagtcagagc ttctaaaatc tcctcacaca
    33661 tgggaatatg aaaaccattt gcgacctcag gacggttcaa ggtaaggatt gccaagtcct
    33721 cttcaagctg ataaataatg tgttccatca gggctccttt ttattttata agcagtttat
    33781 actcttcgaa aatctcttta aaccgcgtca gcttccatct gcaacctcaa aacagtattt
    33841 tgagctgact tcgtctagct tcttagtttg ctctttgatt ttcattgagt gttaaattat
    33901 ttcactgtca aagtatatct tttttaggag cagaaagcaa gaaaaaatcg actgaaagtg
    33961 tctcagccga taagaaaggc tcgctttagg ctagaaagca tcttattttc ttcattgaaa
    34021 aaagcctttc tttctgctat aatcgtataa aatacttact ttaggagttc ttatgaaagt
    34081 tgttaaattt ggaggtagtt ctcttgcctc tgctagtcaa ttagaaaaag ttttaaacat
    34141 cgtcaaaagc gattcagagc gtcgttttgt agtcgtttct gcgcctggta aacgcaatgc
    34201 tgaagatact aaggttacgg atgccctgat taaatactac cgcgactatg ttgcgggtaa
    34261 cgatattagc aagagccaaa gctggattat cgaccgctat gctgctatgg ttagtgaatt
    34321 gggactaaaa ccagctgtgc tagaaaaaat ttctaaaagc attcacgcct tggccactct
    34381 tcctattgaa gaaaatgaat ttctctacga tactttccta gcagccggtg aaaataacaa
    34441 tgccaaattg attgctgcct actttaacca aaatggtatc gatgcacgct atatgcaccc
    34501 tagagaagct gggattgtgg tcacaagtga acctggtcac gctcgcatca ttccatcaag
    34561 ttatgacaag attgaagaat tgacaaacac caatgaagtc cttgtcattc ctggtttctt
    34621 tggtgtcact aaggaaaatc aaatctgtac tttctcacgt ggaggttctg atattacagg
    34681 ttctatcatt gctgctggtg tcaaagctga cctctatgaa aactttacgg acgttgatgg
    34741 tatctttgca gcccaccctg gtattatcca ccaaccacac tcgattcctg agttgaccta
    34801 ccgtgaaatg cgcgagttgg cctatgcagg cttctcagtc cttcatgacg aggctcttct
    34861 tcctgcctac cgtggaaaaa ttcctctggt tatcaagaat accaacaacc ctgaccatcc
    34921 aggtactcgt atcgttctaa aacacagtaa tgatgaattt ccagttgtgg gaattgctgg
    34981 tgactcaggc tttgtcagca ttaacatgtc gaaatacctc atgaaccgtg aggttggatt
    35041 tggccgcaag gttctgcaaa tcctggaaga acttaacatc ggttgggaac atatgccaac
    35101 aggtatcgac gatctttcta tcattctccg ttctcgccaa ctaactccca tcaaggaaga
    35161 agaaatcctg cgtcagttgg ttcaaaaggc taaagtagat catgcagaaa tcgaacacga
    35221 cctttctatc attatgattg ttggtgaaaa aatgaagagc catatcggag tgactgctac
    35281 tgcgacacgc gctctatctg aaaacaaaat caacatccag atgatgtctc aaggttctag
    35341 tgaagtttct attatgtttg ttgtcaataa agaccaagag aaagcagcaa ttaaagccct
    35401 ctacaatgcc ttttttggag aaagtaagga agactaagca tggcccaatc acttaacaaa
    35461 acagtactcc tcagtacgac aggcacttcc tacctctcta tcgctgggaa agttgggaaa
    35521 ttccttgtcg gagatcaggc tttggaattt tacccagatg tcaatgtcga acaatttatc
    35581 cagattcctt ggagccatat caatcagatt ggagccaatg tcactggacg caaaatcagc
    35641 cgccacttcg aagtctttac agacaaagga aaattcctct ttgcttcaaa agactcaggt
    35701 gccattctca aaattgcacg cgaaaaacta ggcaatgaca aggtcgtcaa acttccgacc
    35761 ctgattcaga caattagcca aaaatttaaa aatctatttg caaaaaagta gaaactttag
    35821 tataatcata gcaacggata agtaggttat cttcttcttt cagaaagtct gcgggtactg
    35881 cgagcagata ggggggatag gtgaaattct accgttagta acaattacat acacaatcaa
    35941 gtgcacacct gtgaagttgg atggaaccgt ggccctgcca ctccaacgtt ttgtcaggcg
    36001 tgcttttttc ataaaggagt tcttatgtta gatatcaaac gtattcgtac agattttgaa
    36061 gctgtcgcag aaaaattagc tacacgtggt gtagatgctg ctgtcttgaa tgaaatgaaa
    36121 gaaatcgatg ctaaacgtcg taacatcttg gtcaaggttg aaactctcaa agcagaacgt
    36181 aacacagttt ctgctgagat tgcccaagct aagcgcaaca aggaaaatac agatgacaag
    36241 attgctgcca tgcaaaatct atctgctgag gttaaagcct tggatgctga attggcagaa
    36301 atcgatgcta aattgacaga atttacaacg actcttccaa atatcccagc tgacagcgtt
    36361 cctgttggga ctgacgaaga cgacaatgtg gaagttcgcc gttggggtac tccacgcgag
    36421 tttgacttcg aacctaaagc tcactgggat ctcggtgaag accttggtat ccttgactgg
    36481 gaacgcggtg gtaaggtaac aggcgctcgc ttcctcttct ataaaggcct cggtgctcgt
    36541 ttggaacgtg ctatctacaa ctttatgttg gatgaacatg gaaaagaagg ctatactgaa
    36601 gtcatcacac cttacatagt caaccatgat tctatgtttg gtactggtca gtatccaaaa
    36661 tttaaggaag atacttttga actcagcgat accaactttg tcttgattcc aactgctgaa
    36721 gttcctctga caaactacta ccgtgatgaa atcttagacg gcaaagatct tccaatctac
    36781 ttcactgcca tgagtccgtc attccgttct gaggctggtt ctgccggtcg tgatacgcgt
    36841 ggcttgatcc gtttgcacca attccacaag gttgaaatgg tcaaatttgc caaaccagaa
    36901 gaatcttacg aagaattgga aaaaatgaca gccaacgctg aaaacattct tcaaaaactc
    36961 aaccttccat accgtgtcgt tgctctctct actggagata tgggcttctc agctgcgaag
    37021 acttacgact tggaagtgtg gattccagca caaaacaatt accgtgaaat ctcaagctgt
    37081 tcaaacacag aagatttcca agcccgtcgt gcccaaatcc gttaccgtga tgaagcagat
    37141 ggcaaggtga aactccttca taccttgaac ggctctggac ttgcagttgg acgtacagtg
    37201 gctgcaattc ttgaaaatta ccaaaatgaa gatggttctg tgaccatccc agaagcactt
    37261 cgtccataca tgggtggagc tgaagtcatc aaaccataaa aaataaggtt tagctatttc
    37321 tagctagacc ttttttcgta accaaatcag ataagcacct agtacaaaga ataaaatagt
    37381 taggcatata atggtttcag ccaataccag gtaatccaga aatggaagtt tcaaaattcc
    37441 ctgagccatc ttgagcgagg tcgctgtgat aatggttggg aaggtgaggg ctgagaaggc
    37501 tggttgaaaa ccttgtttta aaatgttggg cagacgagtt aaaacaaaga aaaagaagga
    37561 ttgagaagcc aaaatcatga caatcaagac ccaagtcggc aggctggttc ctcctactcg
    37621 aactagagaa gccaagagta gagagaaagg agcacagtag attccttctt gtccaagcaa
    37681 ggctagtggg agtggatgtt tctttaaatc gctataaata aggggataga gatagaaggt
    37741 caagagaaaa ccaaaactca aggtcgcata ggcaatttcg ataataccta ccagaggata
    37801 ggtcaaggca gccactgcta tccccacata gagaaccgtc caacttggag tggcatgaac
    37861 cctccgccct gaacaagcaa acttgatggt aaaaccagca atcaaggtca aatccaagag
    37921 aaatgaaaac caccaaatcc cttgtgctac caaaggaaga taagagaata cgcgaaagac
    37981 ataggtcgat aaaatcatcc cagccatagg aaaggttgcc attcctgaca aaagaggggg
    38041 cttggtcaat tcttgcttgg tttctttcca attaaagaga tgcagaatta gaaagtaaat
    38101 ccataaaacc aaaccagtca gactaaaaag atgggataga accggcaacg tatctaaaat
    38161 aagatttcca gctcctgcca aacctagcaa acaacctgaa aatactaagg ggagtttttt
    38221 catcctaacc tccaataatc atgttagttt cagtataaca taaaagcgct taaatgagga
    38281 tttaaaaaaa cgaagtccgc ttatttcaga cttcatttta ctcagatatg aattaggcat
    38341 aaggttgcaa ttctggatta attggtgtat tagctaagtt gttggcatag ttacagagga
    38401 ttgctaggct gacaccaaaa accacatcca aggcattttg ttgagtgtag ccagcttcta
    38461 aaaactcaga caaggcttca tctcctacac gacccttggt attgataact gccaaggtaa
    38521 acttagctag ggtatccaat ttaggatctg tttcaattgg agtacgattg cgaagagctt
    38581 gaatcaagtc atcattcatc tggatttgtt tgatggaaaa ggctgtgtga cctgcgacac
    38641 agaaggcaca accattggtc acggctgccg tgatttgcac cacttcacgc tcaacgggtg
    38701 tcaggctgtt gcgacggtgg atagatgaga caatttggta ggcttctaaa acagtcgggg
    38761 cattggccaa gagaccgatt aggttgggaa tatagccatt gttgtctttt tctactgttt
    38821 caagaatttc tttcacttct gctggtgctg actctactgt atggatagta aatgttgtca
    38881 taagatacct cttttcttat tattgacact aatattattg gaaaatctta taaaatcctg
    38941 attcctaagt ttatctaaga taaagcttta ttctctcata agattttcgt tgttatatta
    39001 gtttatcaca cttccaatca cttgcataat atatattata tatcaggctg ataaaaatta
    39061 tttataggca aaaaaatcac acgagctgtg tgattccatt atttgtcaaa atacttttta
    39121 gtttcagcaa taacgactgg cgacaagacc aagagggcaa tcaagtttgg cagagccatc
    39181 aaggcgttaa cgatatctgc gataatccag accatatcca actcgataaa tcctcctaac
    39241 aagaccatga gcacaaaaaa cacacggtag agccagataa agcgagcccc aaagaggaac
    39301 tcaaaacagc gttctccgta atagttccaa cctagaatcg ttgtaaaggc aaaaagtaca
    39361 aggaagatgg tcaagagggc aggcccaaag tgtgaaaaga ctgttgagaa agctgactga
    39421 gtcaaggcaa ccccattcaa gtcaccactc caaactccag ttaccaagat ggtcaaacca
    39481 gttagagtac aaatgatgag ggtatcaata aaggttcctg tcatggaaat caaaccttgc
    39541 tctactggtt catttgtctt ggcagctgca gctgcaatag gagcagaacc cagaccagat
    39601 tcgtttgaga acacaccacg cgccacacca ttttgaatag ccatccgaac gctagcacca
    39661 gcaaatccac ctaccgcagc aaggggacta aaagctgagg taaagactaa agcgattgtg
    39721 ccagggattt ttccgatatt aaagaaaata actgtaagag ttcctaagat ataaatgagg
    39781 gccataaaag gaacaacagt agttgaaacc ttagaaatag acttgagtcc accaaagact
    39841 gcaatcgcta caaagacaga caagacgaga gctgtgatgg ctggcgaaat cgtcgttgta
    39901 ttttggatag attctgtaat cgagttgact tgggtgaagg ttccgattcc caagagagca
    39961 accaatactc ctgctactgc aaacaaaaca gcaagtggtc gccacttttc tcccatccct
    40021 agaaggatat agtgcatggg acctcccgct actgcaccat ggtcgtcctt ggtgcggtat
    40081 ttgatggcca agagtccttc cgcatacttg gtagccattc caaagaaagc cgccatccac
    40141 atccaaaata gagctcctgg tccaccaacc ttgatagccg tcgcaactcc tatgatattt
    40201 cctgttccaa cagttgatgc caaggctgta cacagagctg caaaactgga tacatcacca
    40261 tgtcccttat cctggataaa aataagctga aaggccttgg gcagacgcaa aacctgcaag
    40321 agtcctagcc gcatggttag gtaaatccct gttccgacca ataaaatcaa gaggggcggt
    40381 ccccaagcaa aagcatcgat tgatttaagc aattctaaca tttccttctc ctatcgtttc
    40441 aaccccaaaa gaaagagcac atgcaagata catgtactct ggaatgctta gataaatgct
    40501 aaaaagcggt ctatcctagc tctgtccttt tacctgagag tttgagcagt tgcctgcctt
    40561 gccccttcgg tgcctttacg gtctctccag agttccgtcc atttacagtc atggaaaatc
    40621 aaacgattcc ccacttctat taaacttcat tcggtgttgg tatttaattg attctaattt
    40681 tacaaaaaat gttggctttt gtcaatgtgt ttattagtaa aaattagttc aacagttttt
    40741 actttataaa gtccagaata ctgctatcct ttaaaagtga caatagtcgc accactgcct
    40801 ccagcatttt gtggggcata gccgaaactc ttgacatgtt tgtttctttg caagtatttg
    40861 gtaactcctt cacggatgac tcctgttccg ataccatgga tgatatcaac ttgagccata
    40921 ttgttaagca aggcttggtc gatgaaggta tctagctcat tcatggcttc ttcatagcgc
    40981 ttgcctcgaa gatccagtct agcttgaggt cctcgcccag aagttcgttt cacaacattg
    41041 acctgtttct tcttgactgg tttttcttgc tgggcttgaa caagatcaaa ctctttctct
    41101 tccaaggtca tcttaatcaa gccaacttgg gcttcccagc gaccgtcctt gagttgactg
    41161 gtcaaggtac cacgctgacc ataactgaga accacgatat catctcccac ctttggagct
    41221 cgttttttct tggccttttg aaggacctta tttttagaca agtccacttt ttcaggagcc
    41281 aattttttca acttggcctt ggcttcaatg atttcgtggg gcttgagttg ggatttactg
    41341 tggagatttt tgagaatctg gtcactttca cttagggcca tatccacaat ctcagcagcc
    41401 tgttcacgcg ccttgttaag ctcggtttcc ttttcacgat taagctcgtt gtagagtttt
    41461 tttagcgcac ggttcatctt gagattttct tgctccacct cacggatatt gtccaaacgt
    41521 ttgcggcttt ccagcgtctg ctcttctaat tgctcaatga tacgattgac gtcattgtcc
    41581 tgatcgatct gctgactggc atctcctacg ataacttcag ataggcctag acgtttggca
    41641 atttcaaagg cattacttcg gccaggaaca ccctgcataa agcgataggt cgggcgaaga
    41701 gttgcagtat caaactccat actggcattt tgcacaaagg ctgtctcaat accgtaggcc
    41761 ttgagttctg gatagtgggt cgtcgccatg gtcttgattt gacgcaggcg aaggtcctcc
    41821 agaatagcca tggcaagggc tgctccctct tggggatcag taccagcccc caactcatcc
    41881 aaaagtaaga gtgaatgttg gttgaccttg ccaagaatat ccacgatatt ggtcatatgg
    41941 ctagagaagg tagacaagct ctgctcaata gactgctcat ctccaatatc agcaaagatt
    42001 tcttcaaaaa taccaacacg acttcccttg tctgctaaaa tcggcaatcc tgactgggcc
    42061 atgacctgtg tcaagcccag agttttgagc atgatggtct tcccacctgt attgggacct
    42121 gtaatgacaa tagctgttaa atcttgacca aaatggacat catttgcgac ggcatttttg
    42181 accaaaggat ggcagacatg gagcagttga atctcttgat tttctgacag ctgaggcacg
    42241 actgcttgtc tttcttggat aaatcgaacc ttggcacgaa tcaagtccag atgaccgata
    42301 atccaagcgt cattagcaat ctcagccgca tgagggcgga cacgctcaga aatttcttgg
    42361 agaatgcgaa gcatttcata gcgctcatct gctcgcagac tagcaatttc ttcgctcagt
    42421 ttgactacct cacgtggttc gatatagacg gtgtttccac tagcagaaat atcatgaacg
    42481 acacctgcaa tcttattgcg gtaggtgttt ttgactggta aaacctgacg gccatttctg
    42541 ctagcaacaa ttccttccgt caacatctgc gctttttgct tgagcaagtc ttgtaaaaca
    42601 tcgcgtacct gactctcgct atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg
    42661 gcaaaatttt caatgaaacc cgcatcatta aaggcctgaa gatttccttg taattgcgga
    42721 aaatcatgta atttctcaaa ccaaagggct aattcttcca agctgacatt ttccagattg
    42781 gcataaaaac tttgaagttc tcggctggca agaagcacgc gtttcaagag taggaactcc
    42841 tcgatattga gatccgctcc catctccaac ctcttgcaga ctcctgcaat ttccttagtt
    42901 gagagaatag taaaatgcgg ttgctcgacg aaaagagcct gcatttcttt catctcagca
    42961 aaagcctgtt tgattttatc tgctttggca gtcggagcca gctgtctcaa ttgctccaag
    43021 ccctgctcgg tcaacaaatg aggatcaaac aaggccttga ccttatcgaa ctctaatgtt
    43081 tctaatattt tcttattcat ctttatttcc ttgtctttga atgtctaggt gtggtagctt
    43141 tttacattct gatagattcg agtcaaatct gtaaacaaag ggctaggaaa actcctgccc
    43201 tttttatccg attaaatttg tcacccagat ttgtttgagc caactggttg ttatcggtat
    43261 gctctggatg atgtgttttg cgacgatact cttttcaaga ggattttgta taactgccat
    43321 ggggatggtc gccaagattg tcaaggccat ttgcaagaca aataaggtca ccaacatgga
    43381 caagatacct gctgaaactt ggaacaactt accacccagt tttttgctag gaatcaagtg
    43441 taagagaaga ccaagcaaac gaccaatgct atagaaaatc ccaaatacaa gcaagtagcc
    43501 gatacctgca taaaagacct tatccagctg aaagagttga tccgatggga aaaagaaagt
    43561 cccctgacct tcctgcgaat ttgcataagg gagcaataaa tggaattgct ctccaagccc
    43621 cttataaaac tggccagcca taaaagccga tgccatggct gaaatcaggt aataaacctg
    43681 taagagcagg cctctccgat agccgatata aaatccccaa accaagacca atagaagaag
    43741 gaatgaaatc ataaggaatc ctcaatcttg ctctgttctt gcttacaagt cacaagcttg
    43801 tgacggagtt cttctagctc ttgctcctta tcgtcaaatt caatctcacg gctgagctga
    43861 gttgataaac agttgactgc caacaaaaga gcgattgttt catcatctgc gctaggcatt
    43921 tgttctttaa ttgcttggta tttttctgtc gcaaccttag cgatttcctc cataaaaagg
    43981 ttatcatgtt cgcttgtcaa ggttaacgat tttttcccga atgtaaattt gaatcgattt
    44041 agatttgcca taaaattcac ctcacgatat tataccaaaa ttcgctaatt ttgtcagttt
    44101 ttacaaattt tactgctttt gtggtacaat agaaactatg gcaagtatca cactcacacc
    44161 aagcgaaaag gatattcagg cttttcttga acactatcaa accagtctgg ctcccagtaa
    44221 gaatccctat atccgctact ttttgaaact acctcaagca acggtttcta tctatacttc
    44281 tggaaaaatc ttgcttcagg gtgaaggggc tgagaaatac gctagtttct ttggctatca
    44341 acttgtagag gaaaacaggg ggcaaaatct tcctttaatt gggacagatg aggtgggaaa
    44401 tggttcctac tttggtgggc ttgcagttgt ggctgccttt gtcacatctg accagcacga
    44461 ctttttacga aaactcggtg tgggggattc taagactctg accgaccaaa agatccgtca
    44521 gattgctcct attctcaagg aaaaaatcca gcaccaggca ctccttctct cacccagcaa
    44581 gtacaacgag gtcatcggag accgctacaa tgctgtttcg gttaaggttg ccctccataa
    44641 tcaggctatc tatctcctcc ttcaaaaagg tgttcagcct gagaaaattg tgattgatgc
    44701 ctttaccagt gctaaaaatt atgacaagta cttggcacaa gaggccaatc gtttcagcaa
    44761 tcctatcagc ttagaagaaa aggctgaggg caaatacttg tctgtcgcag tttcttctgt
    44821 cattgcgcgt gatctctttc tggaaaatct tgaaaatttg ggacgagaac tgggttatca
    44881 gctcccaagt ggagctggaa cggcttctga caaggtggct agccagattt tgcaagccta
    44941 tggtatgcag ggactcagct tctgcgccaa attgcacttt aaaaacactg aaaaagcgaa
    45001 aaaacgctta gaaaggtaag ttatgaattc atttaaaaat ttcttaaaag agtggggatt
    45061 gttcctccta attctgtcat tactagcttt aagtcgtatc tttttttgga gcaatgttcg
    45121 cgtagaagga cattccatgg atccgaccct agcggatggc gaaattctct tcgttgtaaa
    45181 acaccttcct attgaccgtt ttgatatcgt ggtggcccat gaggaagatg gcaataagga
    45241 catcgtcaag cgcgtgattg gaatgcctgg cgacaccatt cgttacgaaa atgataaact
    45301 ctacatcaat gacaaagaaa cggacgagcc ttatctagca gactatatca aacgcttcaa
    45361 ggatgacaaa ctccaaagca cctactcagg caagggcttt gaaggaaata aaggaacttt
    45421 ctttagaagt atcgctcaaa aagcccaagc cttcacagtt gatgtcaact acaacaccaa
    45481 ctttagcttt actgttccag aaggagaata ccttctcctc ggagatgacc gcttggtttc
    45541 gagcgacagc cgccacgtag gtaccttcaa agcaaaagat atcacagggg aagctaaatt
    45601 ccgcttctgg ccaatcaccc gtatcggaac attttaagag acctaagagg ccgagaatca
    45661 ccaatctcag cctcttcttc tatcgtgaga agtgattgtt tattgacaaa tactcaacga
    45721 aaatcaaaga acaaactagg aagctagccg taggctgctt aaaacagtgt tttgaggttg
    45781 tggatagaac tgacgaagtc agctcaaaat actgttttga ggttgcagat ggaagctgac
    45841 gtggtttgaa gatattttcg aagagtataa aataaaaaca atcccaactc tcacctattc
    45901 atgcaaagga attttatgga agtttatttt tcaggaacca ttgaacggat tatttttgaa
    45961 aatcccagca atttttatcg catcctcctc ctagaaatcg acgatacgga cgcagaggat
    46021 tttgatgatt ttgaaatcat tgtcacagga accatggctg atgtaattga gggcgaagac
    46081 tatacttttt gggggcaaat tgtccagcac tccaagtatg gagaacaact gcaaatcagt
    46141 cgttatgatc gcgcaaaacc aactagtaag ggcttggtca agtacttttc aagtagccat
    46201 ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg atacctatgg cgaaaatacc
    46261 attgacgaaa ttttgcaaca cccagaaaag ttagaaggca tcgcaggact ctctgccaaa
    46321 aatcgcgagg ctttcgtctc cactctccgt ctcaactacg gaacggagat ggttttgtcc
    46381 aaactagcca actacggcat tcccaacaaa ctagcctttc agattcaaga cttttacaag
    46441 gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc tggttgagga tatcaagggt
    46501 ttgggcttta ccattgctga ccaactagct gaggaactag gcatcgaaag tcaggctcct
    46561 gaacgcttcc gcgccggtct agttcacagt ctttttcagg cctgtatgga aacaggggac
    46621 acctatgttg aagcacggga tttgctggaa caaaccctta ctctccttga gtcttcccgt
    46681 cccgtggaac tagaccccag ccaagttgcc caagagctct cctacctgat cgaagaagac
    46741 aaggttcagc agattgatac caagatcttt gacaacagcc tctttttcgc tgaggaaggc
    46801 atccgcagtc acttggttcg tatccttgaa aaaggaaaac agaagagtca tgatttagaa
    46861 accattcaaa aacatatcac tactatcgag gaagagctgg gaattgagta tgataacatt
    46921 caaaaacagg ctatctgtga tgctatccag aataaggtct ttatcctgac aggtgggcct
    46981 ggtactggta agacaactgt tatcaatgga atcatcgctg tttatgccct gttagaggga
    47041 cttgacttca ggaagaaaag caatctgcct attcttcttg ctgctccaac tggtcgagct
    47101 gctcgtcgca tgaatgaatt gacaggtttg cctagcgcga ccatacatcg ccacttggga
    47161 atgacaggtg acgatgatac cagtcatctg gaagattacc tagatgctga ctttatcatc
    47221 gtggatgaat tctctatggt agatacttgg ctggccaatc aactcttctc caatatctct
    47281 tctaacagta agatcctcat cgtaggtgac agtgatcagc taccttctgt cagtcctgga
    47341 caggttctag cggatctgct tcatattcct ttgattcctc agactcactt ggaaaaaatt
    47401 tatcgacaaa gcaaagaatc aaccatcgtc accctagcta gtcagattcg acagggcatc
    47461 ttgccagctg atttcaccca aaaaaaagct gaccgttcct actttgaaat tgctagtggc
    47521 catattcctg ccaccattga aaaaatctta ggtgccgccc tcagaaatgg tattcctgcc
    47581 cgtgatatcc aagttctggc tcctatgtac cgagggacgg cagggattga tgctatcaat
    47641 cagctcatgc aagacctgct caatccccca caaaaagatc aactcagttt tgaagctcct
    47701 cagtgccact atcgtaaggg agacaaggtc attcatttgg ttaacgatgc tgaaatcaat
    47761 gtctttaatg gggatttagg agctatcaca gacctgattc ctggtaaata caccgaatcg
    47821 aaacaagacg agattgtcat tgattttgat ggtaatgaag tctcttaccc ccgtaacgaa
    47881 tggtacaaga ttcgcttggc ctatgccatg agtattcata agtctcaggg aagtgagttc
    47941 ccagttgtca tcctaccgat tactagtgct agccgacgta tgctggagcg aaatctcatc
    48001 tacacagcca ttacacgtgc caaaagcaaa ctcatcttac taggcgaatt acaagccttc
    48061 gactatgcta cccaacacat cggaactgcc cgaaaaacct atctgattga acgcttcagt
    48121 gatctactgg agaatgttga agaaaagcaa caagctgtct ctgaaacagt cacatcaagt
    48181 gcctctgaac aatcctacat cctaaccgaa gaaaactggg acagcattcc agccatgatt
    48241 gggattacag acacagacct caaagagatt tttggaaaat agtgcatcag aaaaaccacc
    48301 aattcaggtg ggttttctgt ttattaagat tattttactg ttgctgtgct tgtaatcaat
    48361 tcaacagctt ttttgatagt gatatcatgt ttcaacatgt cagctgaaag caagttttga
    48421 acttgtgcaa cttccatgtt gtagtctgct gccaattgct caacttcttt ttggatttct
    48481 tcttctgaag catcaaatcc ttcagctttg gcaactgctt cgataacaag gttagtctta
    48541 gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt cttcttgagt agttccagta
    48601 atttggaagt acatgtcagg gttgatccct tgacgttgca agttcccaag gaattcattt
    48661 actgaacggt gaacttcttc gtggatcatt tcttctggaa gttctacgat ttcagcattt
    48721 tctacagctg tatcaattgc tgcaccttca actgcatctt tgtaagcttc ttctttagca
    48781 gcagccaatt ctttgcggta tttttctttc aagtcagcaa gtgtttcaac ttcttcatca
    48841 atgtcttttg caagttcatc gtcaagagct ggaacttctt tagcttttac ttcgtggata
    48901 gttgtcacga atttagcttc tttacctgca aggtcttctg cttggtagtc ttctgggaat
    48961 gttacgataa catcaacggt ttcgccagct gagtgaccta ccaattggtc ttcgaaacca
    49021 gggatgaatt gacctgaacc aagtccaagt gagaagtttt caccttttcc accgtcaaat
    49081 tcaacaccgt cgatagaacc aacgaagtcg atcacaacag tgtcgccgtc ttcagcagca
    49141 gcttccttga taaccaattc agccaggttg ttgcgttcac gttcgatacg ctcttcgaca
    49201 tcagcgtcag ttacttcttt ttctacatca actgatactt caaggttttt gtagtcaccc
    49261 aattttactt caggttttgt aacaacttca gcagcgataa cccagtcttg acctttttcc
    49321 attgaagtta cgtcaatttt tggttgggca accacttcaa gaccagcctc ttttacagct
    49381 gcttcataag cgtttggcaa aagagcgttc ataacgtctt ggtaaagtga ttcttcacca
    49441 aattttttat cgaagatagg acgtggaagg tgacctttac ggaaacctgg aacattaaga
    49501 gatttcttca ctgacttgaa gacacggtcc aattctggtt tgatttggtc ttgagagata
    49561 gtgaaagtca agacaccacg gtttgtttct ttgttttcaa atgatacaga cattctgtca
    49621 tttctcctta aaatttttta aatacagtct attataacat tttctataaa taaaatctag
    49681 actaatgcag acaattatag acaacaagcc tttttcctaa ctaaaacact cataaagtat
    49741 agacaatttt agactacttt ggatatcttt tggttagtca ttttccaaaa ctaatttatc
    49801 taatttttaa gttatatttg acttcatctt ctcagtaaca tgagtataaa cacttaaaat
    49861 ctttgtttca ttagtataat ctacacgatc cattatcgct gttataggta cttccaattc
    49921 agcaagcaaa cttatatgcg aatatctaaa aacatgagca gtcaatacaa aatcatcttt
    49981 cttaatttca cttttcctaa acctgttttt caaaaagtaa ttgaaacaag ttatcattaa
    50041 gggagaacca ttatttgtaa atatataatc accttcttct aaaagaagat attcttttaa
    50101 aatttctaac actctatcac taataccaat tactctatat gaagctaaac ttttcggact
    50161 atccaaaaac acttcgttat tggacgatta cattatagta aaacgaaata agaacaggac
    50221 aaatcgatca ggacagtcaa atcaatttct aacaatgttt tagaagtaga ggtgtactat
    50281 tatagtttca atctactata caagacgaaa ttgaagaaat ctttccatta taaaacgcat
    50341 attatcaagg tttttaaaca cctaataata tgcgtttttt cctattttaa agacttttat
    50401 ccacctatta tacaaagtta agtatccatc acagtttaca attagccttc attacctaac
    50461 ccattcacca tccttcaaga gagtaacctt taagaaccga ataaataaat ggcaaatttc
    50521 gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa gtatgcactc
    50581 ctactacacg gtgactagca tcataaactg tagatccact agacccctct aaagtatcaa
    50641 cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct gtatacattt
    50701 gatgaacttt aaaattatat gatggatagc ctgtgatagt cacagttatt cctgtcaaat
    50761 ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc tcttctagaa
    50821 ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta aattccttca
    50881 aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga ctaacagtcg
    50941 gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag ttgtgagccg
    51001 ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct acattcattc
    51061 catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac ggatactgta
    51121 aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt gcttttggta
    51181 gtatgaacca tatgttggtg aaatctcaga taatgaagaa tcattagatc ctggaccttt
    51241 ttctagtgtc tcacttacct catattcttc acccgtacta gaaataacac tcaaagcaga
    51301 tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac ccaatttttt
    51361 ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac tattctaaat
    51421 ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc tccattatca
    51481 cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta gaggtactta
    51541 cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat aaagcatgtt
    51601 acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc tttattgata
    51661 aaaaattctg tttggttcaa gttatgaagt agaatctttt ccattaattg agtattggtc
    51721 ttctcttttc ttaacaactg gtggtcaata gcgacacgtc tcagccagat attatctgat
    51781 aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctat ctgcaacctc
    51841 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
    51901 attaagatta tttcttctag ttcagggtgt tcatacacca aactccctac tactcgatct
    51961 aggatatcta ccgtgtccca ccaggatttt gtcacgacta actgctctag cttaggcaaa
    52021 tcggtttcct ttagataaga ctgcattgct ttcaaatagt tagcagccac atattggtat
    52081 tttctaggct ccttttccca gcaagtgtct gcaaaatccc aatcgataat ctttgttttt
    52141 ttcgcttctg gtaaatattt ttatagagtt tatttctttc aggcaccgca atacctagaa
    52201 aagaaaattg atggcgcata taggcttcca tgggccttgc ttttttagag tcttttgctg
    52261 cttctagctc ctcaagtaaa tctgctaaac tcatctaaaa ctcctcttgc cccaccaaat
    52321 ggtgctgaaa ggcatagaca gccgcctggg tacgatcgct gacttcaagt ttggcaagaa
    52381 tattggacac gtgggtcttg accgtcttga gagagataaa gaggtcatct gcgatgcgct
    52441 gattttcgta gcccttggcg atgagttgga gaacatctcg ctcacgcgca gtcaattctt
    52501 catgaagttc catatgattg cggtggtatt caaccttctt gctaacctct tgctcaatgg
    52561 ccagctcgcc agcagctacc ttactgacgg catgaagcaa ttcatctgca ctagaagtct
    52621 tgagcatata gcctttggca ccagcatcta agactggcat gattttttca ttgtccaaat
    52681 aagaggtcac aatcaaaatc ttggcttcag gccattcttt aaggattgct aaggtcgcgt
    52741 caatcccatt catctcaggc atgacaatat ccatgacaat gacatctgga cgcagttcca
    52801 aggccaagtc aatcccttga gacccgttgg acgcctcacc cacaacttct acatcgtctt
    52861 ggaggtcaaa gtagcttttc aagcccaaac ggaccatttc atggtcatct actagtaaaa
    52921 ttttcatctt tactccttta tcattcctta tctaacaggg gaatacggat atcaactgcc
    52981 agcccttgct tgggagctgt taataactga accgtccctg ccatatcttc aacccgctcc
    53041 ttgatatttc gcagtccata actcaagtcg tctaagcttc ctaaccggaa accaatccca
    53101 ttgtccacca ccttcagttg caattcaaca tctgtctgat agaggtagac atctaggcaa
    53161 gatgcctggg catggcggag ggtattgcta atcaactctt gcaggatacg gaagatatgc
    53221 tcctcgattt tcttaggcaa tttcgtcata ttctgcttga gactaaccct aagatcactc
    53281 ttgtcctcaa gctcttttaa gagaatctga atcccttcta tcaagctctt ctgctccagt
    53341 tcaactggtc gcaaatgcaa gagcaaaacc cgcaaatcct tctgggcagt ttctaaaata
    53401 gctgtgacac tctgcaactg ggtctgcatc ttttctctat ccaatttcaa agcctgctga
    53461 ctgatacccg ataaaataat gtgggccgca aacaactcct gactgactgt atcgtgcaaa
    53521 tcccgagcaa ttcgcttccg ttccttctcg ataatttcct cttcctgatc aaggctatga
    53581 ttttcagctt tttgaagagc ctctgtcaaa aggttaagtt tacctgataa ggacttgaaa
    53641 ctggcatcca aatctggatc tacaacctga actacttctt gccctgccaa taaacgcttg
    53701 agattagcct gcatttttct tagagaaagc tcttcgatcc ctcgccaaaa cagggctaag
    53761 agacaggtca tggacatgct gaaaaccaac aataaaaaga caaatttttc tgttttttcg
    53821 acatcgtaca aaaagataga ccagtcaaaa tcaagtattt ccagcaagct gtgggagaaa
    53881 aaaaagacaa ataggaagga ggtgagagca ataatgacat aggcttgttt tttcatcctc
    53941 taaccacctc cacatcacca atcatagtgg tcaagaaaat cttgacactc ttgttactct
    54001 tgagatagtc ttttgtttct tgatgatagt gttcattgcg gagggctcgc ttgggctggt
    54061 tgaaaaaagt caaatcccca tagagacagt taacgctgag actgacttcc acatctacag
    54121 gtacgatgat tttggtcgtt cctaccatct ttctgaggat aatgacattg tcatgattgg
    54181 ttaagatgac tctctccaga tgaatagtgt ccttgcccat gaagcgaaag agattgatat
    54241 catcaaattg gcaagtctgg tagcttgaaa aatgatgaag atttccaaac caacgatttt
    54301 tctccttctt aaccgtcaca acctcttcaa aaaccaaatt ggtctgctct ttttcctggt
    54361 tcatcatcgg gtaaagaaga aagagactat agataaccgc aacaaaaata gctagaatca
    54421 caaaaggatt gagcataacg atgaaaaaga agagaatggt tgccgctact aaaagaagat
    54481 tattcccctc tttaccagta tagtagcgaa tcaaaagcaa aaagaggaat agtatcagca
    54541 gaaaacgcga aaaatgctct gataccatca aaatcagagc tcctgtcaga agacaggctt
    54601 cgataaataa aaagatttta aattttctca taggttcatc ctctcccttc tattttatca
    54661 caattcaaaa aagtcacctc agtctgagga tggaaaaaaa ggcgctggtt acgccttttt
    54721 catctgatcc tttgcttctt ttaattttcc ataaagaaga tagtctactt tttgtagatc
    54781 tgctatggtg gcacagttaa gggaacacat aatcaagcgt agatctgctt tccagccttg
    54841 gacaatgcca atcacttctt caactgtgta ggtttcaacc aattccagaa cggttcgtga
    54901 caatcccaca gccttagcac caaaaaccaa gcacttaatc atatccagcg gattccgaac
    54961 ccctccacta accaagagtt cgaccttatc tttccattct tgggcattga gaagggcctg
    55021 catggtagac tgaccccatt gattgaggta atcacgctgg ccactacgac ggttttcgat
    55081 ataggcaaag ctggtgccac cacgacccga taggtccact gtacgaacac cgaattcata
    55141 ggctctttcg attgtcttgg catccattcc aaagcccact tccttgagga caataggaac
    55201 gggaatttgc ttgctataat ctgctagatg cgattgccag cttctaaact tcctttctcc
    55261 ctcgggcatg agtaattcct gcatgacatt gacatgcact tgcaatagaa caggattcat
    55321 ctcttctaca gtctgaagtc ctaactcgac aggtttgtcc aatccaatat tggttccaag
    55381 gaggagattg ggatgactag acttgacaga aaaagaatca tccgttggat ttttgagggc
    55441 tgcgctataa gaacccgtta caaataaaat accacaggat tccgccacct gagccagctt
    55501 ttgattgatt tctcttccct tattacttcc accagtcatg gcattgatat aaaaaggaaa
    55561 gtcccacttt cgaccagcaa actctgtcga aagatcgatt tcatccagat tgtaaagagg
    55621 caaggaagaa tgaatcagct ccacctcatc aaagctatta taggaacttt tctgctcaag
    55681 ggcatagagg atatgctcgt ccttacgatt tgtcgtcatg tcctatcctt tcttgatata
    55741 agagctcaat ccccagatcg gcccaacgat tttttaaggt tttggttgat tgcgcatcaa
    55801 aactcagggc gatgccacag tcaccaccac cagcaccact actcttggca acggcctgca
    55861 aatcttgact ggcttctttc aactgtctaa gcaaaggcgt gtaaatatct gtactcaagc
    55921 cttctaaaag cttgctggct acttctactt gctcgataat cttttctgat ttcccctgtt
    55981 ccaaggcttc gaccaaagaa accaccgttt cttttgagga acttaaaaaa ttttgattga
    56041 tattttgctt gatttgctgg accatgtgac tcgatacagc cacttccttg gtccatccca
    56101 ctaagaaatc acattctaaa gttggtttca cttgtgaaat tgaaaagccc caatcacgct
    56161 ccagaactgt cgccaagttt tcttcttcta accaagcagc caccttctgg cgatcaaatg
    56221 actggtagag aaccaaatcc tctgccacaa tacaggcaag gtcgcccatg gaaccattgt
    56281 ctcctcgctt gagcaagaca gcgctagtca gcttgaacaa gagctcctga tcaacagaaa
    56341 catcatacag agccagtaaa gccttgacaa ccaagacaac gacgctgcca ctagaaccta
    56401 gaccaaactt tttcccttct cgttccattt tgccacagat ttctagggaa aaagatctta
    56461 aattctgacc gcgaacagcg aggaagtctc ccatcaaagc aatcgtttct tgaatcaagc
    56521 tgtagtcagg attgggcgtt aagtccactg cgaaatcaaa catatctgaa tagatacggt
    56581 agctgtcaga aaaagcaatc tcagccctca tatagatggg aatatccttt atcaaagcta
    56641 actgccctgg ctctaaaata gcatattcac ctgcccaata gagttttccg caagttttaa
    56701 cagcaatcat cttgactcaa atcctttgtt tttgacacaa tcaagcgata acgctgaccg
    56761 aaaatttctg acaaatgctc caagtctttc tcctgacaaa agaccttaac attgggacca
    56821 gcatccatgg taaagtagca ggcctctcct ttctcacgaa gctggcgaac aaagtccata
    56881 gcctcataag aggcatccgt cagataagaa aaggctggac tagcagtctt tgtcgtagca
    56941 tgcatagcca gggcattttt ctccgttaat tctccaatct tggcaaaatc attttccttg
    57001 agataaatca gcatatcctg atagtccttc tcagactgac gaacccagtc gtcaaaagtc
    57061 gtcgaggttt ccacacaaag tttcatcccg tcacggctag agattggttt tttcttgtcc
    57121 tctagcacca acataatcat agctagtttc aagtctgtct ctacagagta aatttctcca
    57181 ctatccttat cccaggctcc tagcggtcca taaaaactcc gagaagaaga gcctgaggca
    57241 aacttggctt cctgcgctaa ctgacttcta tccaatccaa gcttgaaata agcattacaa
    57301 gccttgacca gggcggacaa accactagaa cttgaggaca ggcccgctgc agtaggcata
    57361 ttgttttgag tatcgatacg gacaaagccc tcaccagctg gacgataacg gtcaataatc
    57421 ttactcatct tggcatgctc gacctcattt tgtagctgac cattgatgta aaattcgtca
    57481 gctattacat tggctggtaa aggcgacaag gtcgtctctg tatacatatt ttccaaagtt
    57541 agagaaatac tgctagtagc aggcaccatc tctttttctt ttttctttcc ccaatatttg
    57601 ataatagcaa tatttgcgta ggaacgtact gtcacaggct ctctatccat gtctgaacag
    57661 ctcctttctc ttctaatctt tctgctagtt cttgtgcgtg tgtcaaattg gttaccaagg
    57721 ctatgataca acctcctagc ccaccaccgc tcatcttggc acccagagca ccatggctaa
    57781 gagtcgtttc aaccaaaaag tctgcctcag ggctactgac tccaatttct tttaaatgta
    57841 aatgcgcttg actgaggatt tgtcccagtc cttcagcatc tttttgtgaa atcgcaactt
    57901 ctgcttgctg ggttaattct cccaaggcat gcaaaaacgg tagggcatcc ttgcccttat
    57961 tttgaaccac ttggatggct tcacgagtat gaccataaac acccgtatcg gcaatcacca
    58021 aataggcgga taaatccatc tcaagttctg taaatcctac gttcttgata aagcgaatag
    58081 gttggtcact gagacaggtc ttagcatcca aaccactagg attcatatgg gcaatcatct
    58141 cagctcgatt gaccaagatt tctagtacat catgaggcag atcagcctga tagtagtcaa
    58201 ataccgcacg aatggccgct atgctgatag ccgctgacga acccatcccc cgtttctcag
    58261 ggatagccga gtcaatctca caacgaatgc aggcttctgt gatatccaaa tactccagtg
    58321 aggcataaac cgccatggac aaggtatcct cctcataaag gcgccaagga ctctctgcag
    58381 gaactacctt acaggtcacc tccacctcca aaagaggcag ggaaatggca ggataaccgt
    58441 aaacgaccgc atgttcccct attaaaatta tcttactatg tgcctgaccg acaccaactt
    58501 tttttgtcat tttttccttt tactagacga aaaaacgtct tatttttcat acaagtatta
    58561 attctttcct atctatttta ttatattttc acaaaaaaag cgattgtttc cattcacaat
    58621 cgcttctttc attattgaac ccattcgcca ttatagttga cagaatagcc atctacggtc
    58681 gtattcactg ccaaggcacc tgagctataa gcgtagtacc atctgccatt gacctggaac
    58741 caacctgtcg tcatagaacg acgaaagaaa ctccataccg ttaagtaaag aggaaagtcg
    58801 tgagggatca tgcgccattg acaacctgtt ttagtgacgt acaaagtctc attaacaagt
    58861 actcgtttcg gccatttata ggtgcggtgt ttggagaaat agggttcaat cttagcccat
    58921 tcttgatcgt ttaaatcagt atcatatgct ttgcgtgtca taactctagt ttaacatttt
    58981 ttgtgaatac aagttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat
    59041 gaagtatgct acgggaaact tatgcactta atttgacaat tcaagatgta aaaatatata
    59101 ctatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt tagaaatcga
    59161 tttgactgtc ctgatcgatt tgtcctgtta ttattttatt ttactataat atttgacaag
    59221 ttatcctaaa agtattatta tgttgttgtg ttatagattg attgaatcta actaaaggat
    59281 cctattcaat tactagaact atcacatact caaggtcagc tcacagatga gcaactattt
    59341 tggttacaat gtctactaaa tttaagtcaa acaaataatt tagtcaaaat taaaaaaata
    59401 gaggaacata aatatgatta caaaacagaa tgtaatagtg ttctacgatt tttactagat
    59461 aaaactgtaa attctgaagg aaggatcact tcttcaacag aatttggaaa tttcgtaagt
    59521 aatttatcat tccaacacgg aatagctgga ctactgtttc ctctaaataa attgtacccc
    59581 ccagaactgg attctaaaat actctctatc atcaagaagg cagtgacaat tagaacgaca
    59641 cacatatgaa tatcaatact cactgctatt tggtgatgca ggctatctat ggttactcct
    59701 acatttattt tctatcagta aaaatcaata ctatctacaa ttagcaaacg tcaccgctaa
    59761 gaaattaata gagaattatg atactctaga agaaatagac tttgcattgg gaaaatctgg
    59821 tgtcctatta tcattaataa aatactatca atttaccaat gacaatactc ttaaaacttt
    59881 catccacaat agtatatggg gaaatttatc attatttcct acaaagagat acagccaaag
    59941 aaagcatttt agactatagc tttgctcatg gatattgtga aattgcatat gctttatttg
    60001 cctattctaa agtcttagaa ccttctatgt tctataatga tctccataca ttccatgctg
    60061 aattaaaaaa attattagaa aaagttactt ctaatactga aaatttagga aatttacaac
    60121 tttcttggtg cgaaggaatt tccggaataa tcttatatct ttgtatgtac gattgtgacg
    60181 gaaacaaaga tattattagt aaatatcaag aatttgtttt taaccatcat ctaaaaatga
    60241 tgacaggata ttgccacgga ataactagct tactacaaac cactgtctac aatcaaaaca
    60301 aattactgat gaaaaaaatc caacaggtaa ttttagcatg ttctgaacga gatgatcacg
    60361 gtttactgat gtttcaagga gatagtggta aagcagattt gtttgacttc ggaataggaa
    60421 gcagggggta tattggtgtc tattaaataa taaattccca ttcgatgtgc aaacataagg
    60481 agaaatgtat gaaattattt tggacaaaca acatatatag acagttgctg ctaaacagct
    60541 gtttttcatc attcggcgac agtattttct acctcgccat tatcaattat gtggctcagt
    60601 acaatttcgc tccgctagcg attttactga tttccatttc agagatggtt cccctactat
    60661 cgcaactctt tctcgggatt ctaggagatt ttcaagaaaa tagagtcaaa cacgcactct
    60721 gtattgccaa aatcaaaatc ctgctctacg ctattttgac agtatttctc gtcttgtcgc
    60781 ccttttcatt agtttcagtc attatgattg tcatcatcaa cctcatctct gacaccttga
    60841 gctacctgtc tgcctacatg atgaacgccc tctacatcag tgtaattaag gatgacctgc
    60901 atgatgccat ggggttcagg cagtctctga tgagggttgt ccacattgtc gccaatctgg
    60961 ctggcgcatt ccttatcaat gttataagta ttcaaactat ttcccttatc aacactctga
    61021 cttttgtcat tgcctttttg ggcctgtatg ttattcgaca taccttgtat gaggttgaaa
    61081 aaaggattga aatgtcacat acagcactga gttttaagaa atattttcaa catcttaaac
    61141 agtcgctggc tgtgctcctg aggttaaaag ataccgtcat actactgttt ctgacgacca
    61201 gtatgattgc catcttggat gtgtcccctc ggctgattgc cctccgcttc atccaacaga
    61261 cactagcaca actgagcatt gggcaactct tcgccctgct ctccatcatc atgtcttgtg
    61321 gagctatcct tggcaatatg accagcagta atctatttaa aaatatccgt ttcacgcacc
    61381 tcttggtttt ctgtgagatt tccctattgg ctctaataac tagtatcctt tgtcaagcct
    61441 atatcgtaat tttcgtgacc agtttcatca gttctacgat tatcggcatt ctcagccctc
    61501 gcctacaagc agctgtcttt gcccatatcc ccagtgacaa gatggggacg gtgggctctg
    61561 ctctgagcac agtagacatt ctcgccccgt ccctgctctc cctattagcc ctatccatag
    61621 catcgggcgt ttcggtgcag ttagcattga tatttttgta tcttattttg attgctctta
    61681 tcttttgtca atggttagtc aagttcaaca ctcataacta acgaaaaagc atgtgtagat
    61741 ttcacatgct tttaatctcc ccaatcgtca ggtcaagtac aacaaagtca cttctttgat
    61801 taagcgagtg ttctaatata attataagcg ccctgtcatt accgaaccca ttcgccatta
    61861 tagttgacag aatagccatc tacggtcgta ttcactgcca aagcacctga gctataagca
    61921 tagtaccagt tgccattgac ctggaaccaa cctgtcttca tgtctccatt acctgcattt
    61981 aggtagtacc aagttgaacc atcttgatac caaccagttg ccatagctcc tgatgaacgg
    62041 agatagtacc atttgttccc aaggttttgc caacctgttt tcatatcgcc atttggctgg
    62101 tctaaataat accaagtggt accttcctga taccagccag tggccattgc tcctgaggaa
    62161 cggaggtagt accatggagc aggtttgctt ctatcaatgt caatagtaac atgaaaatct
    62221 tgagtccaac ccttagcaac ttcaccaatt ggtagtggat tgtaagaatc atcaccaaaa
    62281 tttcctagct tatttaaata ataccaattg ccgtcttcat aaatccagcc tgtctttaca
    62341 gcataattat tatcaaaata ataagttctc ttttcagcag atagaggata ttgttcaccg
    62401 tatacttttc ctgtattttc agacgttttt gcctctagta cttgtttatc tgtttgttct
    62461 agcaaagcac catcttgtcc aaaatagtac cacttctcct gaaggccaat ttcgaagact
    62521 ggacgattat caaataaatc atcacgataa cctgttccag gaatttctaa gtattgccaa
    62581 ccgacaacca tctctccaat atcaccaaaa tagtaagttt taccgtctat tttatgccaa
    62641 tagattgctt tatgatcatc ttttacataa tattttctat tatccttatc aacaaatcgg
    62701 ccacctgtgg tattcgcaaa taccgtattt gtagctagca aaccaaagaa aaagactgct
    62761 agtagaactt gcatcatttt tttcaaaagt ttcatttata tatcctccta aaacgattgt
    62821 agcaaagaca cgactgcatg tcaatatata aaaactcctc aaaaaagcag ttacacaact
    62881 gcaactgctt ttctattctt gcatggtgta accaacacca cgcacggttt taatgtagct
    62941 tttttgtcct ttaacatcaa gcttgctccg tagatagcgg atatagacat ctacgatatt
    63001 tgtctcggtc gcactttcat acttccaaac actttccaac aattgctcac gagtcaatac
    63061 tttcttgctt cccataagtg tcgccaaaag gtcatactca cggcgggtca gagcaatcat
    63121 ctcttcacca cgataaaccg tgtgatgttc aacatctatc ctaagattgc ggtaggtcct
    63181 tggaactttc atcagactgc agtgttgatc aatgaagtcc cgacctcgga agatcgccga
    63241 aatacgcgct accagatttt cgataaagac tggcttatag atgtatgaaa ctgcaaaacg
    63301 ctgaacaact tccagctctt cttgcaagtc ttcccaatga tctaaaatca tgatgactga
    63361 ggcaggttta gttcgactca atttttctgc aaaatcctga gccatcatat ctcccagatt
    63421 aacgttcaat aaaatcaaat catagtctgt ctgaagagcc atggaaaggg ctttttgccc
    63481 ctcctctacc agatcaaccc gatactgctc tttctggagt tccaaactta aaaaatgagc
    63541 tagatttcgt tctttctcaa gtaataaaat ccgtttcccc atggctgacc tacttatttt
    63601 tcgtcatacc aagagtagtg gaaggttcct tctttgtctt tacgttggta agtgtgagca
    63661 ccaaagtagt cacgttgtgc ttggatcaag ttagccggaa ggtcagctga acggtagcta
    63721 tcaaagtaag taatagctgc tgagaaagtt ggcactggca caccagcttg aaccgcaaga
    63781 gctacgatat cacgcactgc ttgttgatac ttagcagtaa catccaagaa gtactcgtcc
    63841 aaaagaaggt tggcaagatc tgcatcgcgg ttgtaagcat ctgtaatctt ttgcaagaaa
    63901 cgagaacgga tgatacagcc atcacgccag atagatgcga tatctgcaaa tggcaagttc
    63961 cagttgtttt ctttagaggc tacacgcaat tgagcaaatc cttgtgcgta tgaaatgatt
    64021 tttgagaagt aaagggcttg acggattttt tcaatcaatt cagccttgtc tccttcaaag
    64081 ttgaaggcag ctggttttgg aagcaccttg ctagcatgta cacgttcttc tttgtaagtt
    64141 gaaatgtagc gtgcaaacac tgactcagta atcagtgaca atggtacacc aaggtcaaga
    64201 gatgattggc tcgtccattt accagttccc ttgttacctg cagcatcaag gatgtagtct
    64261 acgattggtc catcttggtc ttcatcgtct ttacggctca agatatcagc tgtgatttcg
    64321 atcaagtagc tatccaattc acccttgttc cactcagtaa agatttcagc catatcctct
    64381 gcagaaaggc ctagcaagtg ttgcatcaag tcatagcttt ctgcgatcaa ttgcatatca
    64441 ccgtactcga taccgttgtg aaccattttc acatagtgac cagctccatc aggaccgata
    64501 taagtcacac atggtttgcc atcttctggt gctttagctg agatttcttc aagaacatcc
    64561 gaaaccaatt cgtaggcctc tttttgtcca ccaggcatga tagaaggacc ttcaagggca
    64621 cctttttcac caccagaaac tccagtaccg ataaagttga tacctgagtt tgccaattct
    64681 tcattacgac ggatggtatc tttgtagaaa gtgtttcctc cgtcaatcaa gatatcacct
    64741 ttgtcaaggt gtggaagaag ggcttggata gtagcatctg taccaggtcc agcttgaacc
    64801 atcagcatga tacgacgagg tttttcgatt gagtttacaa aactttcaac gtcatagctt
    64861 ggtacaaaat tcttttcagg atggcaagca atcacatctt ccgttttttc tttactacgg
    64921 ttgtagatag caactgtgta accacgtgat tcaatattaa gggcaaggtt acgacccatt
    64981 acggccatac ctacgacacc aaagttagct tttgtcattt gacactcctc ttgtttcatt
    65041 tgttttattt tatcattttt acttttgaaa agaaagaatt ttgtaacgac tgcttagtag
    65101 tccaagtcat ccgcatgacc agcgccattt ccgacaaagt agcctgtctt acagttaagg
    65161 gtaaagagat aggttccatc tggcttatag aggttgtaat aaccattgcc gttaacgata
    65221 ttgacacgtt caaggatata ttggtctcca gtgatatagc cacgtgaacg tgaagttgct
    65281 agaatttgtt ccaaaacacc atccgcaaaa tcccaggcag agttattact atcatcaata
    65341 gcagactgat tataggcaac acgactggca cttctttgaa cagcaacccc tgcactcgag
    65401 agacccatat tgacttcact gcgactactt ctagtctcat ttgaactact tggttttggc
    65461 tcactagtcg tatttgaact tgcttgactt gaacttgagc tgctagtttg acttgaactt
    65521 gagctagaag tacttgtttg ctggctctta ccaagactga tagccttatc tagcacttta
    65581 tcaagctccg tatttccagt tttaatatcc gtaaatttag catccgattt ggctttggca
    65641 ttggtatcca acacaccatc cacaatagct ggtttttcaa attgtgcatt gacatcttga
    65701 atggccttga tttgcgttac tagactatca tatttagatt tggcaagcgt atgttcacga
    65761 ctaccttcca gcttatcaag taaagtcttg agttgactca gtttatcaaa ctggctattt
    65821 ttcaaagccg ttttattgct atttgtgtaa aaggcgtcat aaagtgtatt aaaatcatcc
    65881 acatccgatt gattggctgt agttgattga gaagtttcaa tttccttggt cgaacgagcc
    65941 acttgacgat agacataata agcactgaca caaataatta ctgatacaag cgccaaaacg
    66001 gtcaaaataa agcctttttt acttttcttt tctgagtcct cttgatccag acgagaaagg
    66061 ttttgctcct cttccacttc ttcagtcatt tctgttggat tttcatcatc tagcaataga
    66121 ggatccaagc cttgctcctc atcgtccaga ggcaagggta gtaagatgtc ttcagaagat
    66181 ggaacttcct ccgaagaagc ttctgacttc tctacagcct cacgcatctc ttgaattaaa
    66241 tcatccagac tctgagtttc aacgaactcc tcttttttgt attgacgagt cgcaaactta
    66301 tccgcctcaa tttcatctct gtgttgctta acatacttgt ccaaaatgga atcctcaggc
    66361 aagactcctg cttccacttc ttcattttta cgaatagctt gaccaactgt tagctctttt
    66421 gcttcatcaa aatcaaattg cggttcttga ccttcttttt tatgacgatt tcgtcttttt
    66481 ttactcatga gtatcccttt ctattttacc tcttgccgtt tgacacgctg accaaaatat
    66541 tgatatagat ccactttcaa ggttccgttg tataacttac gcttcttatc tgcttggcta
    66601 ccatacttgc tttcaaaagc ttcatcacta gtcaggataa atttgctcca agttttcagc
    66661 ggtgcaaata cttgccccat ctcagcatag agcttggtca ctcctgcatc atctgacaaa
    66721 cgttcaccat aaggcggatt ggaaatgatt actccattga ttttatcgga acgtaaatcc
    66781 tgcacgcgca tctgcttaaa agtaatatct cctgcaacac cagctgcctg agcattggcc
    66841 ttagcaattt ccaccatgcg agcatcaata tcacagccca tgatatccaa ctcaagctta
    66901 cgttctactt ttttagccgc ttctgtgcgc acttcttgaa tcaagcgatc gctgatccag
    66961 ttccattcct caaatgcaaa agagcgacga agacctggcg ccatctttct agcaatcata
    67021 actgcctcaa tacagaaagt ccccgaacca caggtcggat caatcaaagg cttgtctgga
    67081 taccagttag aaagttgtaa aatggctgct gccatatttt ccttgatagg agcgccacct
    67141 ttttcggtac gataaccacg tttaaagagg ctagacccgg tcgtatcaat catgacagtt
    67201 gccacatctt tgagaataga gacctcaatc ttaaactctg ggccattctc catcagagga
    67261 accccttctg ggcgagcata gtgtttctgc aatttcttga caacagcttt cttagaaata
    67321 gcctgaacac tgggctcatt gtgaagtttg gacttaacac atttagcttt tgaaatcggt
    67381 aaccgagctc caagtggtaa ataattttcc caatctaaag cgaaaactcc ctgaaatagc
    67441 tcttcaaaag tcttagctgg gaacgttcct acgataattt tgatacgatc tgctgcccga
    67501 agccaaaggt tggtttcgat aatagctctc acgtctcctt gaaaacgaac acgtccattt
    67561 tcaacctgac aatcgtagcc caactctcgc acttcacgac caacgacagc ctcaagccct
    67621 gctgccacag ttgcaattaa attaaattct tttttcatgt tacagtcttg caagaccttt
    67681 ctatatgtcc actttaaaaa atgaggttga gaaaatttct cagccccaac ctatatgcaa
    67741 ttttctataa gccatgtttt gttccagaag tgactaggac cacttccttc gataatcatc
    67801 tgtctaccac taacagctct agctgatagc agtcagaata ctacgttcgt ttccgcatac
    67861 tccatgcccc gaccaaaatt tgggttgcta gcttgagggg tttaccgcgt tccactctct
    67921 ctgtttccag aaagactccg tcactgtggc actttcaagc ctactctggc ctatccaagg
    67981 acttagccat ttcaactgcc gtaacgattt ctcgtcccta ggcttatggt ttcgcctagc
    68041 acaaacacta caggcatcac agcctgtgct agcatggact ttcctcatga gaagcaattc
    68101 tcctcacgcg attatccaaa aattgcacat ctcaaataac tacttaaaaa tctgagttat
    68161 ctaaaatttg tttaccaaaa acttcttttt ccaatctatt caggcgtttc aaaatatcaa
    68221 aattcgtcat agaacttgta attgccgctt caaggggttc tgcttgaact ggtgaaggtt
    68281 tcggtttacg agttaattct tccttcaaat ccgcaatttc ctgacgaagt gacttgacca
    68341 aggcagcata ggtttcatag tccttgatga catcgtctaa aaactcgtca acttctactt
    68401 tattatagcc acggacttca cgtccaaact cttgttcaaa aatatctttc gctgaaaaaa
    68461 taatacttgc catgtctctc tccattctcg cttgctagta ttattatata aaaaaaggca
    68521 aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt ttcagcaagt tcatttaatt
    68581 gatcaaatgt taatctcttt ataaaatagt cctcttgatt tttcatcttt tggtaaaaat
    68641 aagctagttt tgtttcattt tcttcatcat aaaaaagata ggaactagtc gtgttttcca
    68701 gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc atagcgagga taagcatatt
    68761 tgacaaagtc tacctgctta aagcgactca gtttcatctg attgccttca ttccaatttt
    68821 ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa accgtattcg gttttcatct
    68881 cctgagcaac ctctaaaacc caatattcaa aacccaaact ccctgtaaac acaagccaag
    68941 acaccccatc tgctgccata gcctctaaat ctttacgtat cgctttttta atcaatttaa
    69001 gacgaggatc cttatcagaa aataaaccca aatcaaaagc agaatagcct aaaaccaaag
    69061 ctgtagccat ttttaaccct ttctgtgcaa attatggtat aataaagtga tgttattgta
    69121 ccaataagga gaattatgat caactatcca cataaagttt catcacaaaa aagacaaaca
    69181 tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt cttttgaaaa gatgatcaat
    69241 gctaccaacg actactattt gtctcagggc ttggctgtta tacataagaa accaactcct
    69301 attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg ccaagattgt tgaagcctat
    69361 tttcgacaag cttcaacgac ggactattct ggcgtttata atggatatta catcgacttt
    69421 gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga aaaattttca tccacatcag
    69481 attcagcata tggaacaagt ccttgcccaa caaggaatct gctttgtcct tcttcacttt
    69541 tcttctcagc aagaaaccta cttattgccg gcattcgatt tgattcgctt ctatcatcaa
    69601 gataagggac aaaaatcaat gccacttgaa tatattcgag aatatggata tgaaatcaag
    69661 gctggtgcct tccctcaaat tccttatctc aatgttatca aagaacattt attaggtggt
    69721 aaaacaagat gaacaaacca acgattctgc gcctaatcaa gtatctgagc attagcttct
    69781 taagcttggt tatcgcagcc attgtcttag gcggaggagt ttttttctac tacgttagca
    69841 aggctcctag cctatccgag agtaaactag ttgcaacaac ttctagtaaa atctacgaca
    69901 ataaaaatca actcattgct gacttgggtt ctgaacgccg cgtcaatgcc caagctaatg
    69961 atattcccac agatttggtt aaagcaatcg tttctatcga agaccatcgc ttcttcgacc
    70021 acagggggat tgataccatc cgtatcctgg gagctttctt gcgcaatctg caaagcaatt
    70081 ccctccaagg tggatcaact ctcactcaac agttgattaa gttgacttac ttttcaactt
    70141 cgacttccga ccagactatt tctcgtaagg ctcaggaagc ttggttagcg attcagttag
    70201 aacaaaaagc aaccaagcaa gaaatcttga cctactatat aaataaggtc tacatgtcta
    70261 atgggaacta tggaatgcag acagcagctc aaaactacta tggtaaagac ctcaataatt
    70321 taagtttacc tcagttagcc ttgctggctg gaatgcctca ggcaccaaac caatatgacc
    70381 cctattcaca tccagaagca gcccaagacc gccgaaactt ggtcttatct gaaatgaaaa
    70441 atcaaggcta catctctgct gaacagtatg agaaagcagt caatacacca attactgatg
    70501 gactacaaag tctcaaatca gcaagtaatt accctgctta catggataat tacctcaagg
    70561 aagtcatcaa tcaagttgaa gaagaaacag gctataacct gctcacaact gggatggatg
    70621 tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg ggatatttac aatacagacg
    70681 aatacgttgc ctatccagac gatgaattgc aagtcgcttc taccattgtt gatgtttcta
    70741 acggtaaagt cattgcccag ctaggagcac gccatcagtc aagtaatgtt tccttcggaa
    70801 ttaaccaagc agtagaaaca aaccgcgact ggggatcaac tatgaaaccg atcacagact
    70861 atgctcctgc cttggagtac ggtatctacg attcaactgc tactatcgtt cacgatgagc
    70921 cctataacta ccctgggaca aatacccctg tttataactg ggataggggc tactttggca
    70981 acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt cccagccgtg gaaactctaa
    71041 acaaggtcgg actcaaccgc gccaagactt tcctaaatgg tctcggaatc gactacccaa
    71101 gtattcacta ctcaaatgcc atttcaagta acacaaccga atcagacaaa aaatatggag
    71161 caagtagtga aaagatggct gctgcttacg ctgcctttgc aaatggtgga acttactata
    71221 aaccaatgta tatccataaa gtcgtcttta gtgatgggag tgaaaaagag ttctctaatg
    71281 tcggaactcg tgccatgaag gaaacgacag cctatatgat gaccgacatg atgaaaacag
    71341 tcttgactta tggaactgga cgaaatgcct atcttgcttg gctccctcag gctggtaaaa
    71401 caggaacctc taactataca gacgaggaaa ttgaaaacca catcaagacc tctcaatttg
    71461 tagcacctga tgaactattt gctggctata cgcgtaaata ttcaatggct gtatggacag
    71521 gctattctaa ccgtctgaca ccacttgtag gcaatggcct tacggtcgct gccaaagttt
    71581 accgctctat gatgacctac ctgtctgaag gaagcaatcc agaggattgg aatataccag
    71641 aggggctcta cagaaatgga gaattcgtat ttaaaaatgg tgctcgttct acgtggagct
    71701 cacctgctcc acaacaaccc ccatcaactg aaagttcaag ctcatcatca gatagttcaa
    71761 cttcacagtc tagctcaacc actccaagca caaataatag tacgactacc aatcctaaca
    71821 ataatacgca acaatcaaat acaacccctg atcaacaaaa tcagaatcct caaccagcac
    71881 aaccataaca tttatcaccc agatttttct gggtgatttt gtcatagcac tattgtattt
    71941 atgtgcttaa caaaagcctg agaagatgtc ttctcaggct ttttctgtac tataaacctc
    72001 attggaaaag atagagactg cttccgtaat cttgttaaga ggttttacta aatactagtc
    72061 tttcttcgtt tttactacaa agagagcaga tagggctaga ctaacacttg ctaggaagag
    72121 ggctgtgtca gattgactct cacctgttgc tggcaagatt tgttcaggtg tttctggtct
    72181 agctatttct tgcttataat ctggcgtctt accttgatcg gaaactaaag agctaagttt
    72241 aaactcaggt ttctctacag ttggagcatc tggtttcgta gcagaatctt ttaattggtt
    72301 gagataatct gcaaagtatt ccaccattct ttccgtcaag agatggttat ccgtcgcata
    72361 tttcatgctt gcctgaacgc tagctacttc ctcttgattg tctttgtctg ttaatttctg
    72421 agctttagcc aaagctgctt catagcctga caagtcaaga ggtgtttctg ctacctgtgg
    72481 acgagtaaag atgagttccg ctgcagattg gtatttatcg ccaccatctc cgtaagtctt
    72541 agtacctgta aggacaattt tcttagcctt aattgtctta ccaaaatcaa tgtcttttgg
    72601 cttattgtta tctggccaat cagttgcagt aaaggtatgc tccttgccag actcatctgt
    72661 cacaacaagt ttcacatcac gcaagttacc atttgaacct gatccacgtg gaacgtaacg
    72721 aagtccagtg atttcagttg gttctttcaa gaccatggtt gcaggcttgc ctacatctcc
    72781 accattccaa gatgtatgcc ataaactaga taagtttcca tcaaaggcat ttgcaagacc
    72841 ttcttgagcc tgagcaggag ctgtaagact tgcaaagtca tctgctacca aagccgtttt
    72901 cttctgaacc aaagcattct tcaaggcttc aatcttggca atctctgcac gcgcttcttc
    72961 cacactgata tcatcatcgg cctgactaag gttaaagacc gcctctttca aagcatccat
    73021 agactctttg gtgtagttag tcatggcaac cgttggcaag tagttcttca gagcattttc
    73081 tgtcaacatc ttacctgtta gggtaatttc ttcgatttga agattatcca tcatgaagtc
    73141 gttataacca cggaagttgg catttccacc agaatcacca cgagtattac ttgcattgcc
    73201 agttgagtag atacctaccc aagtatcccc tgtttctgca cctgtcacaa ggaaggttgc
    73261 cttcttggct ttcttagaat ctgtccaagt atttggcaat tcatgcattt ccaagttgct
    73321 tgcttgagtg ccacgacgac ctgactggaa ttctccctta ccgactacaa aagcataggt
    73381 attgtctgaa cctgcttcgt attcaaaggt tacacggtag gtcttacctg cttcaaaacg
    73441 gaagttttgt gggatggttt ggtaaaccaa gttacgacgg ctcactagtc catttgtctt
    73501 gagtgaccaa tttccttcga taacatcatc gactttctta ccgttccaac cacgttgtgt
    73561 atatggatcg tgtttttcag acaagtgagt gcggttgtct tcgacacctt cgacaccacc
    73621 cactacaaat gggaagattc cttgagctac attttcaaag tcttgcttga aggttccttg
    73681 acctgtatcg tgcttgtctc catacatgct tgaattgttt tcaaaggtac gaatttcatc
    73741 aaagtaagtt gcttgatcac cagcttcacg actcaatgtc agagtaacat ttgagacgtc
    73801 cgatcctgtt gtaaagaagg cgtacatgtt ttggaagtaa cttgtatcgt taactgtagc
    73861 attgttacga cgtgtattgt gggcgtaggc ttttacatag ttgagggcga gagacttatt
    73921 ggtataagta gtcacttctt tttcaccagt attcacagtg atacttgcct tggcattact
    73981 acggttatcg acaccgacat aaacggcata cttggtattt ggtttcaagc cagttaattt
    74041 ctgagtgaga ctaacttttt ctttgtttcc ttgaatacga agcatatcgt ttgccccttg
    74101 agacttgaca atttctgcct tagaagcatc gcctgaaatg gtccaatgtt tcaaggtacc
    74161 actgttaaat ccttggtcat agatgtgcat gccttcactc catgacattt caggattggt
    74221 ttgttttgaa cgatagagaa cgtatggttg atttgctaga agatctaggg taattttacc
    74281 atcttttaca gttagttctt gctcttctgt cttaccttgg tcagttagct tgtaaaggta
    74341 aaccttgctc tttgcccaat cgcttggaag ggtccaagtt gttgcaccgg cctgcgtatt
    74401 gaagtagtac atcttttcct tatcagtaga aagtttctta ccatttgcat cccagttcca
    74461 aggagtcaag taagctgaac catcttggat gacacgtccg ttgagagtta ctgtacgttc
    74521 gcgatattgt ggactattga catcatttga cttacgagtt acaactactt tattattgtc
    74581 agcatctacc aattccactc gcatttctgg agtccattta taggtactac cgttatcggt
    74641 catagtcacc ggtgtaccat tttcccattt acttacagtg aagtgttgga agtacttagt
    74701 catgacgtca tgggcaaata agttggttac atagccattg tagtcacttc ttccctgcca
    74761 gccttcaaag tctttcatgc tgtagccacc tagcagtgga tagttggctg caccaccata
    74821 acttctgtag tccccaaccc aagcatcttt ttggtggtta cggataaagc gggtgatggc
    74881 actgttgata cctttattgg tgtagccacc gtaggtcaag tcagctgccc agtgatggaa
    74941 ggtagagtcg tactcaccac catggcccca ctcgatcgca aagcgccagc cttgtttgtt
    75001 aatttcttta gcaagaacgt gggtagccca ggcaccgtta tcacctgatt gaccattacc
    75061 ccaaacgtcc acatagataa agtcgagacc gtcaccaagt tttttcttca aatcttccca
    75121 acgtgccaaa cgaccatgag ctaggtcata ggcagcatca atgttgatac cttgatctag
    75181 ccagttccaa ccatagctat agcttccatc tggattctta cggagaattt tttcattgaa
    75241 gtatttagac tcaggataag tttctgaagc gttaacgtgg atacctagat gagctccata
    75301 tttcttagcc ttctcaatta gggtcttgaa gtcttcgaca ccaccgatac gcttaccaat
    75361 atcagcatag ttcaagtgac cagagtcatg gccttcgcta ccatatcctt taaggaaaac
    75421 accttgccca agaccatctg tgtggagatt gattttcttg ataccatcca aggtcataag
    75481 gaatggattt tgtgcttgag aaccaaagtt catcgcgata cggtaagctg tgatatcctt
    75541 aactttttcc caaccttgag gattgttcat aatgctacga taagcaatgg caccatcttg
    75601 ccaatcgact ttcttgtctg cattggcatc ttcagtgata acaaccttag cacttggaag
    75661 ttccttcgtg tattctggga aaacaatgcc cttataagct ttttcccatt gccattcaga
    75721 gctgtggatt cctacatagt tggcatttcc gactgtttct ttataagctg tcaaacgagt
    75781 ccagtcattc gaaccaccac catagctatt ttgagagtta ctccaaacac cagcagcaag
    75841 cttatctgta gaaacaaatc catacatgta acccttggct aggtctttca ttggattggt
    75901 tacatcgata tgatcatctc cgctgacatg cgtattgttt gacatggttg ccccatcaaa
    75961 cttagcacca gtttgatcac tagaaacaga gactaaagca ttgccgagga aactaataga
    76021 agaaagtagt tttctttcgt catcaatctt ttgacctgga gtgacttgat tgtggttgac
    76081 aatcttggtc acatcaaagt gcaattgatt gtccacaact tgcaagcgta ctgtcatttc
    76141 cgcattgatt aagtgagcat catcgcgaag cttcatcaag tactctgctg ttgtctcatt
    76201 gattttctta taagtgactt caggggtgat tcggtggtta ttgataaaga cttggttgaa
    76261 ctgttgcacc tgtcctggca aagtatgtcc attcaagctg tattccttga cacgagggaa
    76321 ggcttggtca atcactgctt tgaggacctt agactggatc gtatcataag tcaccttgct
    76381 atcgtcaaca accggacctg tttctttctg ggcaggagta tcatccgctt ttacgccttc
    76441 ttgattgtct gttttaacgc tgacaactgt acggtcattg ccataagttc ctgccttgag
    76501 aaggatcttc ttctcatttt taagattatc attgaccgcc ccaggcagtg tcactgtgtc
    76561 aaagagattg acatcgttat tgctggcatt gagttgtcca tctgacttga gagtgataga
    76621 aagacggttt acagaacccg gttctggtgc aactacacgg ttgcctttat accatgtgct
    76681 attacctgga gttttgtatt cccagaacca gccatccttg tcataaccga caaaaacatt
    76741 attattggta tctttaaatt tcaggaagac accaaagcgt gatttgccct tttcagaatc
    76801 ttctttgaag gttaaatcaa cagttgcatt tccattggca tcaacggtca agcccttctt
    76861 ttcaaacagg gctggtttgc ctgcgttatc attttgagca gttgagaata gttggttgta
    76921 gcggacacct ttttcttctc ggatagtgac tgttccctgt tgttcttttt tctctaccgt
    76981 ttgccattca ggagttaccg tcttaggtgt ttcaggttta gcagctgcag gtttatcctc
    77041 ttttggtttt tcttcagccg gtttttcttt ttcaagtgct aatagttctt cttctgtctt
    77101 aggtccatct gtaacttctg gagaaccttg gtcttctccc accttaggcg cttcaaaatc
    77161 acgcccatca ttctcgtttg ctgttgcaag agcagtagct aaatcagctg gtaagttcgc
    77221 cgtggaacca gactgcacgc tatctgcaag aaccggactt gtcccaaaga atgcagctcc
    77281 aatcataaca gaagcaacac ctaatgaaaa tttccgaata ctatatttac aacgtttttc
    77341 aaataatcct ttattcataa acttctaaat cctttcattt tttagcaagc gtttacattt
    77401 cctttttaaa aaatactcct tcctctgaaa gtgcaatgct taaccctgat aaataaaaaa
    77461 taattgtact tttaatataa caaataatag ctgagaaagc aataggaaac aagtaaaatt
    77521 aacaaaaatt ttctctattc tgacaaaaag aggctccaac ttttgggggt cagtacattt
    77581 agaatctttc tttacaaatg taaaaaagga ttcagcattc aagagaaata ctaaatcctt
    77641 tcttatattt tgcaacagtt atttcacatg ttttgcgaga tcttcttgag cctttttatt
    77701 agactcttct ttttctttca tccatttttc ctgagctttt tggtattcat ctacagtgac
    77761 tgccttgtct tgaagttcca agtatttata caagactggt tcacttgtac ctttatttcc
    77821 tgacaatgca aatggtattg taaatggtac catcttagac aagattgggc gccctgtacg
    77881 agatgtagtt ggaataatca aagcactatc tgtcaaccaa gcttgggctg cagcgtattt
    77941 atcatagcgt ttagcaacat ctgtagcctc atcaccagcc tcagtgacca atttttcgta
    78001 gtcatataga cctacttttt tagcagctac attatcttcc cctgagtcaa accctaaata
    78061 tgttttagta ctttctccta cagaaggttt gataatatca aggtaggttg atggatcggc
    78121 aaagtctgga ccccaaccga cattatctga taaatcccag tcttcgccag cagcattttc
    78181 agcaaaatat gtaatattgt ttacttcgtc tttttgtagt tgttggatat caataatgac
    78241 attatcagct cctaaagttg cttccaagga ttgtttcata gattggacgc gctgaacttt
    78301 tgtagttgct gtctggtcaa ctggcatatc caaatgaatt gggaaagtca caccttctgc
    78361 ttgtaaggct gatttagctt tagcaaattc agccttggct ttttctggat tgtaaagacc
    78421 atcctgagaa tctgcaagat taacatcctt ccattcatcc ccataagtga ccaatttctc
    78481 tttgaccata tcgccaaagt ttttaccatc tgcttgaaca aatgttggtg gaacaaagat
    78541 attacgtaag attttgcttg ctccagtttg tccattcaac tgagaggcat aggctgtacg
    78601 atcaaaacca aaggcaatag cctgacggaa atccttgttt aagagagcct ttttagtcga
    78661 tgccttttgt tcgtcgctgg tcttagatgt atatttatag gactgacggt caatatttgt
    78721 accaactaga tacgtaatag agccttgttg agtatagaca atattgtcct tcatactctt
    78781 ctcaagctct gcgaaacttg cacttgttgg atagagacga gctgctgtaa ggctaccatc
    78841 tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc cagaatgaca atttaacttt
    78901 gtcaacatgc acattgtcct tatcccagta gttcggattt ttcgcaaatt caacagagga
    78961 ttttgtcaca atggatttca acaaataagg accgttatac aagagactac ttggatccgt
    79021 cgctttggca aaatcatccc cttttgagtt caaaaactct tcattaactg gcgcaagcac
    79081 acccatggtt gtcttagaat tccagaagct ttctggtttg ttcaaagtgt actgaactgt
    79141 ctgatcatcc aaagccttaa ttcctacttg tgagaaatct ttgatttccc cttttacata
    79201 ggcatccaac cctttgattg attcttgaac aaggtaaaga gcatctgatt ttttatcagc
    79261 agcatatttt agtcctgtta caaagtcttg agctttgact gccgcgtatt cttcaccttc
    79321 agaagtatac cattttgcat ccttacggat agtataagtg taagtcaatc catccttgga
    79381 tacagaccaa tcctcagcca tagacggcac aaagttcccg tagcgatcat tttctagcaa
    79441 accatcaacc acgttactgg taatatttgc tgtcgcagcc ttagcagttg tcaaatagtt
    79501 gaggttatca gggtctgtct cataaatgta tgagaatgtc ttctcacctt tagtgcttga
    79561 acctgatcca gagcatgcag ctaaagtagt cgccgccaat aatgtcacgc ccgcaagggc
    79621 aagtagtttt gaacttttca tccttttctc ctttaaaact ttctctccat tatagactct
    79681 tttcagaaag ttgtcaacag aattttcaga atttttgaaa attatttttc aaataacatc
    79741 tttgcaaaaa atatgaatat cgtaaccg
//
LOCUS       DAVBED010000004        68997 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBED010000004 DAVBED010000000
VERSION     DAVBED010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.004"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            65..393
                     /locus_tag="VQ547_000237"
                     /pseudo
     CDS             65..393
                     /locus_tag="VQ547_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            390..608
                     /locus_tag="VQ547_000238"
     CDS             390..608
                     /locus_tag="VQ547_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542164.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(665..949)
                     /locus_tag="VQ547_000239"
     CDS             complement(665..949)
                     /locus_tag="VQ547_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2542165.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1003..1938)
                     /locus_tag="VQ547_000240"
     CDS             complement(1003..1938)
                     /locus_tag="VQ547_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2542166.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2042..2485
                     /locus_tag="VQ547_000241"
     CDS             2042..2485
                     /locus_tag="VQ547_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2542167.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2601..2867
                     /locus_tag="VQ547_000242"
     CDS             2601..2867
                     /locus_tag="VQ547_000242"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2542168.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2864..3238
                     /gene="crcB"
                     /locus_tag="VQ547_000243"
     CDS             2864..3238
                     /gene="crcB"
                     /locus_tag="VQ547_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2542169.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3232..3561
                     /gene="crcB"
                     /locus_tag="VQ547_000244"
     CDS             3232..3561
                     /gene="crcB"
                     /locus_tag="VQ547_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2542170.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3680..4027
                     /gene="rplS"
                     /locus_tag="VQ547_000245"
     CDS             3680..4027
                     /gene="rplS"
                     /locus_tag="VQ547_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2542171.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4070..4141
                     /locus_tag="VQ547_000246"
     tRNA            4070..4141
                     /locus_tag="VQ547_000246"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4103..4105,aa:Arg,seq:cct)
     gene            complement(4308..5306)
                     /locus_tag="VQ547_000247"
     CDS             complement(4308..5306)
                     /locus_tag="VQ547_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2542172.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5349..6155)
                     /gene="yidA"
                     /locus_tag="VQ547_000248"
     CDS             complement(5349..6155)
                     /gene="yidA"
                     /locus_tag="VQ547_000248"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2542173.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6168..7472)
                     /locus_tag="VQ547_000249"
     CDS             complement(6168..7472)
                     /locus_tag="VQ547_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2542174.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7544..7921
                     /locus_tag="VQ547_000250"
     CDS             7544..7921
                     /locus_tag="VQ547_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2542175.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            8012..8344
                     /locus_tag="VQ547_000251"
     CDS             8012..8344
                     /locus_tag="VQ547_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2542176.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8356..9927
                     /gene="ffh"
                     /locus_tag="VQ547_000252"
     CDS             8356..9927
                     /gene="ffh"
                     /locus_tag="VQ547_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2542177.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10122..11405)
                     /locus_tag="VQ547_000253"
     CDS             complement(10122..11405)
                     /locus_tag="VQ547_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2542178.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11708..12421)
                     /gene="rsmG"
                     /locus_tag="VQ547_000254"
     CDS             complement(11708..12421)
                     /gene="rsmG"
                     /locus_tag="VQ547_000254"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2542179.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12515..13075
                     /locus_tag="VQ547_000255"
     CDS             12515..13075
                     /locus_tag="VQ547_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2542180.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            13077..13976
                     /gene="htpX"
                     /locus_tag="VQ547_000256"
     CDS             13077..13976
                     /gene="htpX"
                     /locus_tag="VQ547_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2542181.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(14020..15579)
                     /locus_tag="VQ547_000257"
     CDS             complement(14020..15579)
                     /locus_tag="VQ547_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2542182.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15818..16135)
                     /locus_tag="VQ547_000258"
     CDS             complement(15818..16135)
                     /locus_tag="VQ547_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2542183.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16314..16856
                     /locus_tag="VQ547_000259"
     CDS             16314..16856
                     /locus_tag="VQ547_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2542184.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16856..17485
                     /gene="nth"
                     /locus_tag="VQ547_000260"
     CDS             16856..17485
                     /gene="nth"
                     /locus_tag="VQ547_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2542185.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17696..18217
                     /gene="pyrR"
                     /locus_tag="VQ547_000261"
     CDS             17696..18217
                     /gene="pyrR"
                     /locus_tag="VQ547_000261"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2542186.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18236..19159
                     /locus_tag="VQ547_000262"
     CDS             18236..19159
                     /locus_tag="VQ547_000262"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2542187.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19209..20288
                     /gene="carA"
                     /locus_tag="VQ547_000263"
     CDS             19209..20288
                     /gene="carA"
                     /locus_tag="VQ547_000263"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2542188.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20600..23776
                     /gene="carB"
                     /locus_tag="VQ547_000264"
     CDS             20600..23776
                     /gene="carB"
                     /locus_tag="VQ547_000264"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2542189.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(24051..24860)
                     /locus_tag="VQ547_000265"
     CDS             complement(24051..24860)
                     /locus_tag="VQ547_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2542190.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24862..25665)
                     /locus_tag="VQ547_000266"
     CDS             complement(24862..25665)
                     /locus_tag="VQ547_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2542191.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25675..27162)
                     /gene="tacF"
                     /locus_tag="VQ547_000267"
     CDS             complement(25675..27162)
                     /gene="tacF"
                     /locus_tag="VQ547_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2542192.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27498..28205
                     /locus_tag="VQ547_000268"
     CDS             27498..28205
                     /locus_tag="VQ547_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2542193.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28210..29232
                     /locus_tag="VQ547_000269"
     CDS             28210..29232
                     /locus_tag="VQ547_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2542194.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29249..30118
                     /gene="licA"
                     /locus_tag="VQ547_000270"
     CDS             29249..30118
                     /gene="licA"
                     /locus_tag="VQ547_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2542195.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            30108..30986
                     /locus_tag="VQ547_000271"
     CDS             30108..30986
                     /locus_tag="VQ547_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2542196.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30998..31687
                     /locus_tag="VQ547_000272"
     CDS             30998..31687
                     /locus_tag="VQ547_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2542197.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31785..32633
                     /gene="dprA"
                     /locus_tag="VQ547_000273"
     CDS             31785..32633
                     /gene="dprA"
                     /locus_tag="VQ547_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2542198.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33517..34560
                     /locus_tag="VQ547_000274"
     CDS             33517..34560
                     /locus_tag="VQ547_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2542199.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34727..36814
                     /gene="topA"
                     /locus_tag="VQ547_000275"
     CDS             34727..36814
                     /gene="topA"
                     /locus_tag="VQ547_000275"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2542200.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            37035..37394
                     /locus_tag="VQ547_000276"
     CDS             37035..37394
                     /locus_tag="VQ547_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2542201.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37487..38119
                     /locus_tag="VQ547_000277"
     CDS             37487..38119
                     /locus_tag="VQ547_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2542202.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38163..38819
                     /locus_tag="VQ547_000278"
     CDS             38163..38819
                     /locus_tag="VQ547_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2542203.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38838..39932
                     /locus_tag="VQ547_000279"
     CDS             38838..39932
                     /locus_tag="VQ547_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2542204.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39944..40981
                     /gene="leuB"
                     /locus_tag="VQ547_000280"
                     /pseudo
     CDS             39944..40981
                     /gene="leuB"
                     /locus_tag="VQ547_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40978..41247
                     /locus_tag="VQ547_000281"
     CDS             40978..41247
                     /locus_tag="VQ547_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2542205.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41251..41610
                     /gene="leuD"
                     /locus_tag="VQ547_000282"
     CDS             41251..41610
                     /gene="leuD"
                     /locus_tag="VQ547_000282"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2542206.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41772..42340
                     /locus_tag="VQ547_000283"
                     /pseudo
     CDS             41772..42340
                     /locus_tag="VQ547_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42434..42499
                     /locus_tag="VQ547_000284"
                     /pseudo
     CDS             42434..42499
                     /locus_tag="VQ547_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42662..44593
                     /locus_tag="VQ547_000285"
     CDS             42662..44593
                     /locus_tag="VQ547_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2542207.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            44580..45932
                     /locus_tag="VQ547_000286"
     CDS             44580..45932
                     /locus_tag="VQ547_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2542208.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            46107..47093
                     /locus_tag="VQ547_000287"
     CDS             46107..47093
                     /locus_tag="VQ547_000287"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2542209.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            47157..47228
                     /locus_tag="VQ547_000288"
     tRNA            47157..47228
                     /locus_tag="VQ547_000288"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47190..47192,aa:Arg,seq:ccg)
     gene            47411..48109
                     /locus_tag="VQ547_000289"
     CDS             47411..48109
                     /locus_tag="VQ547_000289"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2542210.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            48100..51639
                     /gene="smc"
                     /locus_tag="VQ547_000290"
     CDS             48100..51639
                     /gene="smc"
                     /locus_tag="VQ547_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2542211.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51636..52430
                     /locus_tag="VQ547_000291"
     CDS             51636..52430
                     /locus_tag="VQ547_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2542212.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            52430..53248
                     /locus_tag="VQ547_000292"
     CDS             52430..53248
                     /locus_tag="VQ547_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2542213.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            53252..54472
                     /gene="ftsY"
                     /locus_tag="VQ547_000293"
     CDS             53252..54472
                     /gene="ftsY"
                     /locus_tag="VQ547_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2542214.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(54518..56005)
                     /locus_tag="VQ547_000294"
     CDS             complement(54518..56005)
                     /locus_tag="VQ547_000294"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2542215.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(56154..56894)
                     /locus_tag="VQ547_000295"
     CDS             complement(56154..56894)
                     /locus_tag="VQ547_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2542216.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56894..59059)
                     /locus_tag="VQ547_000296"
     CDS             complement(56894..59059)
                     /locus_tag="VQ547_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2542217.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59232..60185
                     /locus_tag="VQ547_000297"
     CDS             59232..60185
                     /locus_tag="VQ547_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2542218.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60262..62250
                     /gene="uvrB"
                     /locus_tag="VQ547_000298"
     CDS             60262..62250
                     /gene="uvrB"
                     /locus_tag="VQ547_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2542219.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            62260..62823
                     /locus_tag="VQ547_000299"
     CDS             62260..62823
                     /locus_tag="VQ547_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542220.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            62789..63277
                     /locus_tag="VQ547_000300"
     CDS             62789..63277
                     /locus_tag="VQ547_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542221.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            63350..63817
                     /locus_tag="VQ547_000301"
     CDS             63350..63817
                     /locus_tag="VQ547_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2542222.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63814..64329)
                     /locus_tag="VQ547_000302"
     CDS             complement(63814..64329)
                     /locus_tag="VQ547_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2542223.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64341..64868)
                     /locus_tag="VQ547_000303"
     CDS             complement(64341..64868)
                     /locus_tag="VQ547_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2542224.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(65146..65709)
                     /locus_tag="VQ547_000304"
     CDS             complement(65146..65709)
                     /locus_tag="VQ547_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2542225.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65693..66244)
                     /gene="coaC"
                     /locus_tag="VQ547_000305"
     CDS             complement(65693..66244)
                     /gene="coaC"
                     /locus_tag="VQ547_000305"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2542226.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66256..66945)
                     /gene="coaB"
                     /locus_tag="VQ547_000306"
     CDS             complement(66256..66945)
                     /gene="coaB"
                     /locus_tag="VQ547_000306"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2542227.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            67175..68845
                     /locus_tag="VQ547_000307"
     CDS             67175..68845
                     /locus_tag="VQ547_000307"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2542228.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        20992 a        12371 c        15088 g        20546 t
ORIGIN      
        1 aggctgcaga ggcaggagaa tttgttacaa ttgatgcctt atttcaggct tataaaaagg
       61 agtgtggatg aacgcctttt tagaagagct ttcacaagct tatccagatg attatctttt
      121 actcgttatg gacaatgcta tatggcataa atcaagtgcc ttaaagattc cgactaatat
      181 tggctttgca tttattcctc catacacacc agagatgaac ccattgaaca agtgtggaaa
      241 gagattcgta aacgtggatt taagaataaa gccttttaaa ctttggaaga tgtcatgaat
      301 caactccaag atgttataca aggactggag aaggaggtga taaagtccat cgttaatcgg
      361 agatggacta gaatgctttt tgaaagcaga tgagtataag tcctcgtttt gaagccttgg
      421 aacaggccat tgcctccaaa gatttggaaa aagtccgaga agcttttaag aaaatgaatt
      481 ccacttggac catcaatgaa agtgtggttc gtgacaatag tacagctcat tatggacgtg
      541 ttgaaacagc tatttccttc ctgcctagta gcatggaaac cgaacctaca gatgagtctg
      601 gaacatgaaa acagcagttg atttcaagaa acaaaaaaga acagtcgaaa ctgttctttt
      661 atcattattt gagaccgtat tttttgttga aacgatccac gcgtccatct gcttgagtga
      721 acttttgacg tccagtgtag aatgggtgtg agtctgatga aatttccaca cggatcaatg
      781 ggtaagtttc gccttcgaac tcaactgttt cgttagagcg ttttgttgaa ccgctaagga
      841 attggtaacc agtagttgtg tccatgaaga caactgggcg atattctgga tggatatctt
      901 ttttcatttt gcaatatttc ctttctgcca tggtctcttt gcgagccata gattgttacc
      961 atactagtct atcagattct gaaaagtttg gcaagtattt tatcagtttt taagcaagtt
     1021 ttttaacttt tggtagatga tttcattttc ttctaggcta taggaattag caccacttgc
     1081 tagagggtgg cctccaccat catgctcctt ggcgatttca ttgataggat ggattttact
     1141 gcgtaagcga acgcggtagt ggccatcagc ctgttccaca aaaattcccc agagactaac
     1201 actatcaata cgcccaggtg cacctacaat ggccgcagtt tcagcatcgg ttacattgta
     1261 ttgtttcaag attttctgac tcaggataac gcgagcagca ccattttcat ccacttccag
     1321 atggtcgtag atgtagcctt gcagtttagc aattttgtag ctcatagtgt ccattttgcg
     1381 agtgagagcc gcaaagtcaa agttatgttc tctcaaataa gcagccaggc gaagagtccg
     1441 tgcagtggta gaagggtaga ggaagcgacc tgtatcaccg acaattcctg caaagagcaa
     1501 ctcagcatcg cgatctgcca aggctagttg ggttgtttgg gcaaataggg taatcatctc
     1561 gctagcgcta cttgaactag tatcgaccca agacaggtca ccgtatacat catcatttgg
     1621 atggtggtca atcttaatga gaaaatcacc ttgactatag cgcttatcat cgatacgagc
     1681 agtattagct gtatcacaga cgatgacaag tgcgccttgg taggctctat cttcaacaag
     1741 atccatctca gccatccaag taagagttgg ttcatcaaaa ccgacggctt tgatggtttt
     1801 ttctgggaaa tgatgttcca gcaaggcttt caatcccacc tgacttccca aggcatcagg
     1861 gtctggtttc atatgacgat gaatgataat ggtgttgtat tctttaattt tttctaaaat
     1921 ttgttggcaa atctccataa ataacctcaa ttctttctca tttcattgta gcacaagaat
     1981 ttttattttt aaaatgaaaa agatgtgata taatggagaa agataaattg aggaggacga
     2041 tatggcatta gcaaaaattg tatttgccag tatgaccggt aataccgaag aaattgcaga
     2101 tattgtagca gacaaattac gtgacttggg cttggatgtt gatgttgatg aatgtacaac
     2161 tgttgacgct tcagacttct tggaagcaga catcgctatc gttgcgacct atacttatgg
     2221 tgatggtgaa ttgccagatg agatgatgga cttctacgaa gacctagcag atctcaactt
     2281 gaatggcaaa atctacggag tggtcggctc aggagatacc ttctacgatg aattctgtaa
     2341 ggctgttgat gactttgacc gtgtctttgt gtcaacagga gcagaaaaag gttcagagtg
     2401 tgttaaagtt gatctttctg ccgaggaaga agatattgaa cgcttggaac aattcgcaga
     2461 agaattggct gctaaagtag gataagcata aaagtgcgct gatgtaatca atcagtgcat
     2521 ttttcttatc gagagttggg attttactag cctaattgat ggctttttga tacaataatt
     2581 caaataaagg aggagactgt atggatttag atattattcg tcaagaaatc gatcaaatcg
     2641 acgaccaaat tgtcaaactg ttagaagaac gaatgcattt agttgagggg gtggttgctt
     2701 ataagaaagc ttcaggtaaa ccgattttag atactaagag agaagaagtt atttttgaaa
     2761 aggttaggag tcgtgtagag gacaagcgct atcaggagac tattgtcgcg actttttcgt
     2821 acatactcaa acgttcgcgt gattatcagg atcaaaatat caaatgaaaa aagaacaatt
     2881 ttatccgcta ggaatttttc tagctgctat gttgggcgga cttgtccgat atctagtttc
     2941 cacctggtta ccagccagtc cagactttcc ttggggcact ctctttgtca actatctggg
     3001 aattttctgc ttgatttttc ttgtcaaggg ctatctggtc tataagggga ctagtaaggg
     3061 cttgatttta gcactgggga cgggtttttg cggaggttta acaacttttt ccagcctaat
     3121 gcttgatact gtgaagctgc ttgatacagg gcgttatttt agtttagtcc tgtatttgct
     3181 tttgagtatc ggtggaggcc tgcttttagc ttactatttg gggaggaaga aatggtaatc
     3241 gtctatcttg caatcgcctg tggcttggga gcactcgtac ggtatttctt ttctcgctat
     3301 aatcaagctt ctaaattgcc actcggaacg ctcatagcta atcttttagg ttgtttttta
     3361 attggagtat tctacaatca tgtagagtct aaggaagtat atgctattct agcaacagga
     3421 ttttgtggcg gtttaacaac tttttcgacc ttgaatgacg aacttcaaag actgctaagt
     3481 gataagaagg tcttttattc ttacctgact ttgacttaca taggtggttt ggttgcgatt
     3541 tttttaggaa ttttgctata aatttcttta ctttttttta gaaatttggt aaactatatc
     3601 ttgtgtgtaa tggacgcaca aaaatacagt ttatccgctg aggaagattc ctcaagattg
     3661 acaaagatag gagaataaaa tgaatccatt aatccaaagc ttgactgaag gtcaacttcg
     3721 tacagatatc ccatcattcc gtcctggtga cactgttcgt gtacatgcga aagttgtcga
     3781 aggtaaccgt gaacgtatcc agatttttga aggtgttgtt attgcacgta aaggtgctgg
     3841 catctctgaa aactacacag ttcgtaaaat ctctaacggt gtaggtgttg agcgtatctt
     3901 cccaatccac actccacgtg ttgaaaaaat cgaagttgta cgttacggta aagtacgtcg
     3961 tgcgaaattg tactacttgc gtgctcttca aggtaaggca gctcgtatca aagaaatccg
     4021 tcgttaattc gactaaaaaa ctctgctttt tcagcagagt ttttatctag ctcccttagt
     4081 tcaatggata taacaactcc ctcctaagga gtagttgcag gttcgattcc tgcagggggc
     4141 atgtaattag atatcaaaga agtttgtcaa agagtctttg atattaaaag aacgcataat
     4201 ataggggatt gtctccataa tattatgcgt tttattattg aaaaatttgg gcaatcatca
     4261 gataaaattg agactatatc gagtatataa atgtttgtat agtcaattta ttcaaaatcg
     4321 tcaagttcta aattatttaa aggactataa cattcatatt tctttaagta attgtttatt
     4381 tcttcagcag tggaacgagg taaattaact cttaaatagt caatatcttc cttagataaa
     4441 aaatgatttg cattcaaaat tgagaagcga aataatgctt catcaaaagc aaaatcataa
     4501 tcgtcatcag ataatgattc cattaatgtt tgaatatgtt ttagtgagta gtcaggtatc
     4561 gaatcgggat aatatactgg ataatcagtg gctgaaaaat tgttttctaa tcctgaaata
     4621 gtaattatca aagattctat gtaatatatt aaagcatgtt taatattacc ttcttgttcc
     4681 aaatgtcttc cctgagcctt tcgtgtgtta gataagcatc caaaatctcc tgatacagta
     4741 ttcctatgag cttgtttatt taagagactc cattttatat caccaaaagt tgctttaaaa
     4801 gagatattgt ttttttcttt acaataatct tccatactta tgtctttatc atagtatgct
     4861 ttgatatagt cactatgttc gataataaga ttttgtgctt cttttgttag tttaaattcg
     4921 aacggaatat ctaaattgtc aatgttaaca ttattaatta ttcttgtaat taattctgct
     4981 ttttttccag aagtagctaa attatgttta gataatatag tttttaattc tactactgta
     5041 agatatgata aagtcttatt tttagtgaag tatcctaatt tgtataattg attgtgtgta
     5101 gattcagggt caatttgaag agagtattta aaatatcttg ggaaattata atttctccct
     5161 gttttttgag tccaatctat gagtatgagt tgcccaggag taaggccaca ttctaattcg
     5221 tttaggtaaa aattgttaca atcagaattt gtgtctctat tatgattatt ttgttttaaa
     5281 ttaaatagtt tgctaaaaaa attcattgga ttttattgct aatcaattct tattgaaaaa
     5341 tgatactttt acagtaccca tgttcggatg gcatgggcaa cgccggattc gtcatttgtt
     5401 ttggtgatgt atttggcgat ttttttgatt tctggatttc cattttccat gacaacgggg
     5461 tttccaacga cttccagcat gggacggtca ttttcttcat caccgattgc catggtttca
     5521 tctttggtca atccgagttt ttcagccaag tgagtaatgg ctgaaccctt gtctacattc
     5581 tttttaagga gttcgaggta gaaaggagca gatttgttga tggagtagcg ctcgtaaaat
     5641 tctgctggaa ttttttcaat cgcagcatcg agaatttctg gttcatcgat aaacatacat
     5701 ttaacaattt ctttgccagc catttcttca ggggtacggt agaagatagg catgctgacg
     5761 agggttgatt cgtgtacagt gtattttccg atattgcgat ttgcagtata gataccgtcc
     5821 ttggtaatgg catgcatgtg gacaccgagc ttgcgactga ggaattccat atccagataa
     5881 tcctcatagg tcaaggattc gctgataatc tcatggccag tagcagtttc ttggacaagg
     5941 gcaccattga aggtcaccac atagtcacct tggtctctca actgcaagtc gtccagaagt
     6001 ttggcaacac ctgcgatggg gcggccagtt gcaatcacga ctttgacacc agcttctttg
     6061 gcatcttgga tggcagaaaa gacttcagga gtgatttcct tttggctgtt gactagggtt
     6121 ccgtcaatat cgacggcaat tagtttaata ctcataaaat tcctcttcta gtttttattt
     6181 ggggtaaaat gatcgttctc aatcaagtgt aaaaattgct gggtaatgct tgcgaagatg
     6241 ctgttttggt ctaacatttc tttagggaaa tagaaacgat tatctccgtg gcgactgcca
     6301 gcaagggatt ggacgatagg agacaggcta gagagttcgg ccagttctcc atttttttgt
     6361 aaaatctcaa tctgtgtccg tggattttga gattcgggac gatagatatc ataagggagg
     6421 tcaaagttct tatgaatggc agtatagtag tcgggatcaa agccgatgtc ctcaaccaat
     6481 tttctcatgc tagtaagttg atcttggtcc tcttgtgaaa aggtaatgga tttaaagacc
     6541 ttgcggttga caaagcgttg agataaatct gcaagaattt tgtcaggact agtcatccaa
     6601 agctggaagt aggtattcat cacgccatca tccagagcca gatagtcagt caaggtcaca
     6661 tttttttcga agaaaggcag gagatgtggg gaagttcgtg caaagaaatt cttgtcctca
     6721 gggtagagtt ccttggcgcg cttgagaaga ttctgtagga gaacttccat ggcgcgtgtt
     6781 gctgggtgga aataaacctg catgtacatc tggtagcgac tgaggacgta gtcttcgatg
     6841 gcgtgcatgc cattgcgctg aaaggcgata ccattttcga caggacgaat gactcggagg
     6901 atgcgagtca ggtcaaattc cccataggat gctcctgtaa aataggagtc gcgcaagaga
     6961 tagtccatgc gatctgcgtc aatctgacta gaaatgagct gcacgacctg cttattagga
     7021 taggtatggt caatgacact ggccaccttt tctgggaaat caggtgccac ttgtagcagg
     7081 acttggtgaa tctctgtctc aggattttga ataatctcct gagtaatggc ttcatggtct
     7141 gtatcaaaga gattttcaaa agtatgggag taggcaccat gcccaaggtc gtgtaggaga
     7201 gcagcggtca cggtcaagag agactcggca ggattccatt cctcaggata tttttcttcg
     7261 aaaatctctg tgatgcgtcg tgcaatttca tagactccta gacagtgaga gaagcgactg
     7321 tgttctccac cgtggaaggt ataactggaa gttcccagtt gtttgatccg gcgcaaacgc
     7381 tgaaattctt ttgtattaat caagtcatag atgatttgat tattgacatg gatgtagttg
     7441 tgaactgggt cacggaatac tttttcgttc atatgaccat tatagcaaaa tcctgctctt
     7501 tttggtaaaa tagtaggaca agagacaaga aagagggcct gatgtgaaga ttcggatgcg
     7561 aaatacaatt cagtttgatg agcagttgga agtgattgac cagctttatg atgtggaagt
     7621 gcatgaaaaa ggagattata gctacctgct tttctataat gaggaaaagg aaaaagtagt
     7681 gattaaattt catggtcaag aacttatgat gagccgattt tctaatccca agaccattat
     7741 gcgctttcta aaggatagcg atagtttagc ctatattcct acacctatgg gcatgcagga
     7801 gtttatcatc caaacgagcc attatcaagt tgataggcaa aagattgaac tagattatca
     7861 actacaaaat caagagggac atccttttgc cagctatcaa ttggaaatta cttggggcta
     7921 ggctcatgtc tttttcaaat ttagctatct atcttcttgg atcggcttcc tagtgtggta
     7981 gattaggcta atttttggta taataaaagt tatggaaatc gaaaaaacca atcgtatgaa
     8041 tgcgctcttt gaattttatg cggcgctttt gacagataag caaatgaatt atatcgagct
     8101 ctactacgct gatgattaca gccttgctga aattgccgag gagtttggtg tcagtcgtca
     8161 ggctgtctat gacaatatca agcgaacaga aaagattctg gaagattatg agatgaaatt
     8221 gcacatgtac tcggactata ttgtccgcag tcagattttt gatcagattt tggagcgcta
     8281 tcccaaggat gactttctgc aggagcagat agaaatttta acaagcattg ataatagaga
     8341 ataagaggaa gaaaaatggc atttgaaagt ttaacagaac gtttgcagaa cgtctttaaa
     8401 aatctacgta aaaaaggaaa aatctctgaa tctgatgtcc aagaggcaac caaagaaatt
     8461 cgcttggcct tgctcgaggc cgacgttgcc ttgcctgttg taaaggactt tatcaagaaa
     8521 gttcgtgagc gtgcagtcgg gcatgaggtc attgatacac ttaatcctgc gcaacagatt
     8581 attaaaatcg ttgatgagga actgacagcc gttttaggtt ctgatacggc agaaattatc
     8641 aagtcaccta agattccaac catcatcatg atggttggtt tacaaggggc tggtaaaaca
     8701 acctttgctg gtaaattggc caacaaactc aagaaagaag aaaatgctcg tcctttgatg
     8761 attgcggcgg atatttatcg tccagctgcc attgaccagc ttaagacctt gggacaacag
     8821 attgatgtgc ctgtctttgc acttggaaca gaagtaccag ctgttgagat tgtacgtcaa
     8881 ggtttggagc aagcccaaac taatcataac gactatgtct tgattgatac tgcgggtcgt
     8941 ttgcagattg atgagctcct catgaatgag cttcgtgatg tgaaagcatt ggctcaacca
     9001 aatgaaatct tgcttgtcgt tgatgctatg attggtcagg aagcagccaa tgttgcgcgt
     9061 gagtttaatg ctcagttgga agtgactggg gtcatcctta ccaagattga tggcgatact
     9121 cgtggtggtg ctgctctgtc tgttcgtcac attactggaa aaccaatcaa gttcactggt
     9181 acaggtgaaa agattacgga cattgaaacc ttccacccag accgcatgtc tagccgtatc
     9241 cttggtatgg gggatatgct cactttgatt gagaaagctt ctcaggaata cgatgaacaa
     9301 aaagcccttg aaatggctga gaagatgcgc gaaaacacct ttgattttaa tgatttcatc
     9361 gatcaattag atcaggtgca aaatatgggg ccgatggaag acttgctcaa gatgattcca
     9421 ggtatggcca acaatccagc ccttcaaaac atgaaggtgg atgaacgcca gattgctcgt
     9481 aaacgtgcca ttgtgtcttc gatgacacct gaagagcgtg aaaacccaga tttgttaaat
     9541 ccaagccgtc gccgtcgtat tgctgctggt tctggaaata cattcgtcga agtcaataaa
     9601 ttcatcaagg actttaacca ggctaaacag ctcatgcagg gtgttatgtc tggggatatg
     9661 aataaaatga tgaagcaaat ggggattaat ccaaataacc ttcctaaaaa tatgccaaat
     9721 atgggaggaa tggatatgtc tgcccttgaa ggaatgatgg gacaaggcgg tatgcctgac
     9781 ttatcagctc tcggaggagc aggaatgcca gatatgagcc agatgtttgg tggcggtttg
     9841 aaaggtaaaa ttggtgaatt tgccatgaaa cagtccatga aacgtatggc taacaaaatg
     9901 aagaaagcga agaagaaacg caagtaagac aagagattga tgcaaatctc atttgatgag
     9961 aaaataaagt aaaaatttct atgataaaac gtacagtatc aaggttttag aatatctgat
    10021 attatacgtt ttttgatttt aataattttg ttaagacact tttattatgg tatacgaaaa
    10081 atccactcag ctgtctgagt ggattaggtg tatttagact cttagtcttt attttcgtat
    10141 ggcaagatca agttcaagat gattcctgtc atggctgaaa gggcagtacc tgaaagtgta
    10201 actggaccaa gtttaaggat agctcctcca agtccaagaa ccaacatagc acttgcgatg
    10261 atgaggtttc gcatttgagc gaaatcaaca cgttctttaa tcaagacttt caaaccattg
    10321 ctggcgataa ccccatagag aaggattgac ataccaccaa gtacagcgtt tggaatagtt
    10381 gaaatcaagg cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa ggcagcgtta
    10441 cggataactg agacagaagc gatacgagtc ataccgataa cccctgtatt ttctccgtaa
    10501 gttgtattgg ctggtccacc aaggaaggca gaaacagaag ttgcgatacc gtcaccaaga
    10561 agagtacggt gaagacctgg ttcttttaag aattgacgac cacagatttg acccaaaaca
    10621 gtatggtctc cgatatgttc agaaattgtt acgatagcga ttggcaagat agcgatggct
    10681 tctggaccaa agtaaagatt gtactcttta aaggcaccac ctgtgctaaa tggcaagtag
    10741 aaaccaggaa tttcgaacca gttggcttta agaactggtg taaagtcaac caagccaaga
    10801 gttagtgcga aaaggtaacc accgataatg gcaaagagga atggaatgat tcgtaggaag
    10861 ccttttcctt ttgtattgat aaaggcagca attaggaaag taacaacggc taccagagca
    10921 tttttccaat ttccgtctgc tacaagacct gcattggtaa cagctgaacc tgcaagtcca
    10981 agaccgataa cgatgatcat aggaccgata atgattggtg gcaagagttt atcaatccat
    11041 tttgttccta caaatcggat gctggtagca acaaggacat agaccaaacc agtcaagata
    11101 acccctgttt gggcagcaga tacatccccc cccatttctt tcatagccag tgacatagct
    11161 gtgataaagg caaatgaaga acctagataa actggaactt taaaaccagt agcaatcatg
    11221 tagatgagtg ttccaacacc tgaagcaaaa agggcaacag atacaggcat tcccaaaatc
    11281 aatggtacca agatggtcgc accaaacatg gcgaaaacgt gttggaaact aaggagaatt
    11341 ccttttccag ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt tgattcttgt
    11401 ttcatataaa cctcactttt gggcatcaaa aaagagccca ttattttaca gcaataggcc
    11461 ctcagagtaa gacttcttta aaatttagat tttaaagagt tttaaatatt tctgcgtctt
    11521 cgtcacctca cgggatgaca ttaaaaacct ttgcttagga tagtatagca gaaaaaaatg
    11581 attttgtaaa tcattttttc ccgagcctag aaataaaaga gcgaggctga ttttgtaaat
    11641 cattttttcc cgagcctaga aataaaagag cgaggctgat tttgtaaaca tttgtttact
    11701 aaaaaattta aagtgggcgt ttatttggca taccagcctt acgcggatat ttatttggtg
    11761 tttctttttt cttttctacc actgtgatat agcgcggatc tctattcggt agggcgtagc
    11821 tgagattgtc ttcgacctta ctaaaaagga gattgagggc attcttagct tctaataatt
    11881 cctcaggcgc attgctggcc ttgagtgcca atagttttcc accaacctta aggtagggaa
    11941 tggtcaattc agataggacc tgcatacggg caaccgcacg agctgttaca aaatcatatt
    12001 gagcacggaa gttcttgtct tgggcaaaat cttcggcacg tccgtggtag aaatgaactc
    12061 cgttcaaatc cagttcttga gccaagagtt gtaggaagtt gatgcgctta ttgagtgaat
    12121 caataatggt cacatctaac tccggataga gaattttcat tggtagacta ggaaatcctg
    12181 ccccagcccc gatatcaaga agtttgatag tttcattggg aatcaaacct tgaagaatgg
    12241 gtgcaatcga atcgtaaaaa tgtttgagat aaacttcttc cttgtccgta atcgccgtca
    12301 aattaatctt ctcattccac tcgaccaaga gctcaaaata acgttcaaat tgttcttttt
    12361 gctggtccga aagtggaaga ttctgctcgg caagcaagtt gtaaaatgtt tttggtttca
    12421 tagttatttc cttctttagt atcatcttat tttaccacaa tcatagaaaa tttgatatac
    12481 tggtactaat ctaaaagcag aaaggactta tattatgact tggattattc ttggagttat
    12541 cgctcttatt gttatttttg tgattgttag ctataacggt ttggttaaaa atcgtatgca
    12601 aaccaaggag gcttggagtc agattgatgt tcagttgaaa cgtcgaaatg acctcttgcc
    12661 aaacttgatt gagactgtaa aaggttatgc caaatatgaa ggttctaccc ttgaaaaggt
    12721 ggcagaacta cgtaaccaag tggcggcagc gacttcacca gcagaagcta tgaaagccag
    12781 tgatgccctc actcgtcagg tttcaggtat ttttgcagtt gcagaaagct atccagattt
    12841 gaaagctagt gctaactttg ttaaattgca agaggagttg acaaacacag aaaataaaat
    12901 ttcttactct cgtcaactct ataacagtgt tgtcagcaac tacaatgtaa aattagaaac
    12961 tttcccgagc aatattatcg ctggaatgtt tggatttaaa gcggcagatt tccttcaaac
    13021 atctgaagag gaaaagtcgg ttcctaaagt tgattttagc ggtttaggtg actaagatgt
    13081 tgtttgatca aattgcaagc aataaacgaa aaacctggat tttgttgctg gtatttttcc
    13141 tactcttagc tcttgttggt tatgcggttg gttatctctt tataagatct ggacttggtg
    13201 gtttggttat cgcactgatt atcggcttta tctacgcttt gtctatgatt tttcaatcga
    13261 cagagattgt catgtccatg aatggagcgc gtgaggtgga tgagcaaacg gcaccagacc
    13321 tctaccatgt agtggaagat atggctctgg tcgctcagat tcctatgccc cgtgttttca
    13381 tcattgatga tccagcctta aatgcctttg cgacaggttc taatcctcaa aatgcggctg
    13441 ttgctgcgac ttcaggtcta ctagctatca tgaatcgtga agaactagaa gctgttatgg
    13501 gacatgaagt cagtcatatt cgtaattatg atatccgtat ttcgactatt gcagttgccc
    13561 ttgctagtgc tatcaccatg ctttctagta tggcaggtcg tatgatgtgg tggggtggag
    13621 caggtcgcag acgaagtgat gatgaccgag atggaaatgg tcttgaaatc attatgctag
    13681 tggtttccct actagctatt gtactggcac ctctcgctgc aaccttggtt cagctcgcta
    13741 tttctcgtca gagggaattt ctggcagatg catctagtgt cgagctgact cgcaatcccc
    13801 agggaatgat taatgcccta gataagttgg acaatagcaa acctatgagt cgccacgtcg
    13861 atgatgctag cagtgccctt tatatcaatg atcctaagaa aggtgggggg ttccaaaaac
    13921 tcttttatac ccacccacct atctcagaac ggattgaacg tttaaaacag atgtaaaaga
    13981 atccagaggt cgtctctgga tttttgctat gttgcaaatt tataaatctt ctaaattaac
    14041 tagcttcaaa ccgtgttctg tcatgcgata gatgatcgag cagacttctt ttaagaaacg
    14101 acggtcatgc gaaacagtga tgagaccgcc tggataggtt gcaaagagtt ttctgatttg
    14161 gggttgagaa gtgggagaaa agtttcgtgt gggttcatcc agcaggagaa agtttggttt
    14221 gcgcagaact agatccaaaa gcaggagttt tccctgttgt ccgccagata aggagcgaat
    14281 ttgatgctgc atttctggat aactgaaatt gagactggct aggtgagatt ggattttctg
    14341 aagttcctct ttttccccag ttttgctgat ataagctatt gaggataaat ccaattgcag
    14401 ttttttgtgg taatcttgtg gcataaaacc aagtgaaatc tctcttttat cattcagaag
    14461 ttgctgtaat ttggctaaca gagttgattt cccaacacca tttgggccga tgataccgat
    14521 tttttcttgg ccacggacag ttagttgcag ttcctgagcc aaaacacggt cgtcaatgga
    14581 caaattttct ttttccagtt ggactaagac tttagaagct ggtaatggtt ggatgtctga
    14641 aaagaaaagt tggatttgtt cctcttcaag tggcttttga gtcatggact gagctgtctt
    14701 ttcgtagcgt ttttcttgtg agaggacagt tttcatcttt ttagccaata ggcgaccggc
    14761 agtactatct ttggtagctc gaagcgcagt ttctacattt tgcttaactc tccgatgttt
    14821 ttccatggtt ttatcgtagg ctctttggtt gttagcagct tgctgacttt gtttggcaaa
    14881 attagccttt ctctgctcac tatagctatc atagtctaaa tgctctacta gcgtttccgc
    14941 ttctttacgg tgtttgacca gtcgcaagtg aacaatagtg tctgccgttt cagaaagaaa
    15001 gtcttcatca tgggaaatga aaataacggt ttgcctggtc ttttgaatct ggccttttag
    15061 ccaatcaact gtctcaaggt ctaggtcatt tgaaggttca tctaaaaata gaatctcaaa
    15121 gggtttggct aactcatgga taagctgaat tttcaaagct tcgccccctg atagattgcc
    15181 aatctcttgg tcacttgcga aacgattgct atcaaaatgc aattcctccg ccaaacgata
    15241 gaggatactg tagtctaaat caatagaatc taaaaagaag tagtcgtgta aagttttctt
    15301 ttttaggtcc tcagggactt tttgaggaat gtaggccagt gactgataat cagactggat
    15361 gtctcccttg atagtgaaat cagacaaatc ttcccccatt aaagttttaa gtaaggttga
    15421 tttaccattt ccttcttcgc caataatagc taccttttcc ccgtcttgta tggtcatgct
    15481 taggtcagag acaaggtctc gtaaatcttt gttttgtgtg atggtcaggt gattgatttt
    15541 tatcatacta ttgccctttc tagaatgtcg atagtgcata acaaaaagct ctactttacc
    15601 tagtagagcc caaagtctat gtcaaaaaaa ctctattaac atgccagaaa aagagcataa
    15661 aagagcacac aaaaagagac aaaaacaaga tctactaaat aaaggttctt tatttgatag
    15721 acttagttgt tcatgtctcc cttacctccg agtattagta tctttatact atacttttaa
    15781 ggaaattttg tcaacagaaa actggaaatt ctatgctcta aaatccaaaa acaggtccat
    15841 agagacttag tacgtgtttg acatgctcgt aatggatttt atcatagttt cgccaagcag
    15901 tgcgtgcttg atcgtttagt tttaggctac ccagtccaat cagaggactg gtgggttggt
    15961 aaaatttctc aagatcaatt aagatactgt tgttcaactt ttccgttttt ttgagctctt
    16021 gcatagtagt gtttagcagc tcttgtagtc gaatatcatc tgccgtaccc tgtttacagt
    16081 tttggtagct tttatttaac ttggatagga gttgaatgag tttcttgtct tccatgtctt
    16141 ccatatgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
    16201 aaaactgtca tagtaaatat gttaaaattt tgaattttaa ttacaaagtt tggtgtgctg
    16261 atttgtagcc ttttcatggt ataatcaaga gagtaaatct ttatggagga agtatgaaat
    16321 taaatattca agaaattcgt aagcagtctg aaggtttgaa ctttgaacaa acgttagatt
    16381 tagttgatga cctgcgtgca cgtaatcaag aaattttaga tgtaaaagat atccttgcag
    16441 ttgggaaagt acaatatgaa gaccgtatgt atttcttaga ttatcaacta tcttatacca
    16501 ttgttcttgc ttcgagtcgc agtatggagc cagttgagtt agttgaatct tatccagtca
    16561 cggaagtttt catggaaggc gcaactaacc agctagatca agaagtttta gatgatgact
    16621 tggtcttgcc cattgaaaat ggggagcttg accttgctga gagtgtatca gacaatatcc
    16681 tgctaaacat tcctatcaag gtcttgacgg ctgaagaaga agctggtcaa ggatttatct
    16741 caggaaatga ctggcaaatc atgacagagg aagaatacca agctcaacaa gcagtaaaga
    16801 aagaagaaaa cagtcctttt gctggcttac aaggactatt tgacggagat gaataatggt
    16861 cttgtcaaaa aaacgagcac gaaaggtgct agaagaaatc attgccctct tcccagatgc
    16921 caagcctagt cttgatttta ccaatcattt tgaactcctg gttgcggtca tgttatcagc
    16981 ccagacgaca gatgcagcgg taaataaggc cacaccaggt ctctttgttg cctttccaac
    17041 accccaagct atgtctgtag cgacagagag tgagattgct tcacatattt ctcgcttggg
    17101 attgtatcgg aataaagcta aattccttaa aaaatgtgcc caacagttac tagacgattt
    17161 tgatggtcaa gtccctcaga cacgtgaaga attggagagt ttggcaggtg ttggtcgcaa
    17221 gacagccaat gttgtcatga gtgtaggatt tgggattcca gcctttgcag tggatactca
    17281 tgtggagcgt atttgcaaac accacgatat tgtcaaaaaa tcagcgacgc cacttgaggt
    17341 ggaaaagcgg gtcatggata tcttgccgcc tgagcagtgg ttagctgccc atcaggccat
    17401 gatttatttt ggaagagcca tttgccatcc aaaaaatcca gagtgtgacc agtacccaca
    17461 attatatgat tttagcaatt tgtaagatgc tacattgaaa ctttttgctt gattttaagc
    17521 atgctttgtg ctatagtaaa tgataactaa atattccttt aaacctgtcc cgtgaggcag
    17581 gcaaggagcg cgataaagta gaagggtgaa gtctatactg tttgcagtag ggctcgcttg
    17641 gctataaatt tcaagtctcc ttgtttaagg agacttttct ttttggaggt ttgtcatgaa
    17701 aacaaaagaa gttgtagacg aattgaccgt caaacgagcg attacgcgta ttacttatga
    17761 gattatcgaa cgcaacaaag atttgaataa gatcgtcttg gctggtatta aaactcgtgg
    17821 tgtctttatt gcccaccgaa tccaagaacg tttgaagcag ttagaaaatc tttcagttcc
    17881 tgttgtggaa ttggatacta aacctttccg tgatgatgtt aaaagtggag aagatacttc
    17941 tttggtttct gtcgatgtga cagaccgcga agttatcttg gtggatgatg tgctctatac
    18001 aggtcgtacc atccgtgctg ctattgataa tattgtcggt catggtcgtc ctgcgcgtgt
    18061 gagtttagca gttctagtcg atcgtggaca tagagaattg ccaatccgtc cagattacgt
    18121 tggaaaaaat atcccaacca gtcgttctga agaaatcatc gtagagatga cagaacttga
    18181 tgaccaagac agagttctga ttactgaaga agcttagaaa gttaaaggag tagccatgtc
    18241 agaaaatcaa caagcattga accatgtggt gtccatggaa gacctcactg tcgatcaagt
    18301 aatgaaattg atcaagcgag gaattgagtt taaaaatgga gcccagcttc cctatgaaga
    18361 ccatccgatt gtttccaatc tcttctttga ggattctaca cggacacata agtcctttga
    18421 agtcgcagag attaaacttg gattggaacg acttgacttt gatgtgaaga ctagttcggt
    18481 taataagggt gagacacttt atgacaccat tttgactctg tctgctttag gagtggatgt
    18541 ctgtgtgatt cgccatccag aggtcgacta ctatagagaa ttgattgcta gtccaacgat
    18601 tacgacttcc atcatcaatg gtggagatgg ttcgggccaa caccctagcc agagcttgct
    18661 tgatttgatg accatttatg aggaatttgg ccactttgag ggtcttaaag ttgctattgc
    18721 aggtgacttg gaccactcac gcgttgccaa atccaatatg cagattttga aacgcttggg
    18781 agctgaactc tttttcgctg gacctgagga atggagaagt caagagtttg cagactatgg
    18841 aaagtttgta accattgatg aaatcattga tcaggttgat gtcatgatgt ttctccgtgt
    18901 gcaacacgaa cgccatgata gtggagctgt attttcaaaa gaagactatc atgcccaaca
    18961 tggcttgact caagaacgtt acgatcgttt gaaagaaaca gcaatcctca tgcacccagc
    19021 tccaatcaat cgtgatgtag aaatagcaga ccacttggtt gaagcaccaa aatcacggat
    19081 tgtccaacaa atgaccaatg gtgtctttgt tcgaatggca atcttagaat ccgtactagc
    19141 gagtagaaac gccaactaaa acacaagacg ttaaaagacg ccagtgagcg tccacgagag
    19201 gtgaaaatat gacaaaaaga attctagtat tagaagatgg cacagttttt gaaggcaagg
    19261 ccttcggagc agatattgat gtaacaggcg aaatcgtctt taatacaggg atgaccggct
    19321 accaagaatc cattacagac cagtcttata atggacaaat cttgaccttt acttatcctt
    19381 tggtaggaaa ttatggtatt aatcgtgatg attatgaatc cattattcca acttgtaagg
    19441 gagtcgttgt ttttgaagaa gcgcgtagag ctagcaactg gcgcaaccaa atgaccttgg
    19501 atgaattttt gaaagccaag aaaattccag ggatttcagg aattgatacg cgtgctctta
    19561 ccaagattat ccgtaagcat ggtactatgc gtgcaacctt gacccatgtt ggggacagta
    19621 tggaccatgt gacggaccag ctccaagcaa cagttttacc gacagacaat atcaaacagg
    19681 tttctactaa aacgtcttat ccagctccag gagttggttt gagcgtggtg ctagtggact
    19741 ttggtctcaa gcactcaatc ctacgtgaac tttctaaacg caactgtaac gtgacagttg
    19801 ttccttattc gacaacggct gaagaaattc tccatctcaa tcctgatgga gttatgttgt
    19861 caaatggtcc aggtaaccca gaagacgttc cacaagcact cgacatgatt cgcggtgtac
    19921 aaggaaaaat tccaatcttt ggtatttgta tgggacacca actctttgca atggcaaacg
    19981 gggctaagac ctataagatg aagtttggcc accgtggatt caaccatgcg gtacgtgaaa
    20041 tcgcaacagg acgagtagac ttcaccagcc agaaccatgg ttatgcagtc agccgcgagg
    20101 atttgccaga gcacttgatt attacccacg aagaaatcaa tgacaagtca gtggaaggtg
    20161 tgcgccacag ataccaacct gctttctctg ttcaatacca cccagatgca gctcctgggc
    20221 cacacgacgc tagctaccta tttgacgagt ttatcgagat gatggaagtt tttaaacaat
    20281 caaactaaga atgagtaaaa gctcgtcgga gaatttatgt aactgaacat ggacggaaag
    20341 ctcagaattt agagaaacca acttggattg tcaatccttc cttgatttcc taaaattcaa
    20401 tcgctttcta gtcgtccttt gtatcttatt taatgtcgcc ctgagaggcg acgaatagaa
    20461 aggagaagat acattgttcg cggaagtgaa cacgccctaa gaactgtgtg aaaaagataa
    20521 acatcgtctt gacgctgaag gcgtctgcgc cgagtttcct attttcactg tgttctttac
    20581 gggctttgta tcataaacta tgcctaaacg tactgatatt caaaaaatta tggtgattgg
    20641 ttctggtccg attattattg gtcaggctgc tgagtttgac tacgctggga ctcaggcttg
    20701 cttgtcgttg aaagaggaag gttatgaggt tgttttggtt aactcaaatc ctgcaaccat
    20761 catgacggac aaggaaattg ctgacaaggt ttacattgaa ccgattacac ttgagtttgt
    20821 gacacgtatt cttcgtaagg aacgtccaga tgccttgcta ccaacactcg gtggtcagac
    20881 aggtctcaac atggccatgg aattgtctaa aaatggtatc ttagatgagc ttggcgttga
    20941 acttctgggt accaaattat ctgccattga ccaagcggag gaccgtgacc tctttaaaca
    21001 attgatggaa gagcttgaac aacccattcc agaatctgaa attgttaaca cagtagaaga
    21061 agcagttgcc tttgcagcga caattggcta cccagtcatc gttcgtccag cctttaccct
    21121 cggtggtact ggtggtggta tgtgtgccaa cgagaaagaa ttgcgtgaaa tcactgaaaa
    21181 tggtttgaaa ttgtcacctg ttacccaatg tttgattgag cgttcgattg ccggtttcaa
    21241 ggaaattgaa tacgaagtga tgcgtgactc agctgacaat gccttggttg tttgtaacat
    21301 ggaaaacttt gacccagttg ggattcacac gggggattcc attgtatttg cccctgcgca
    21361 aaccatgtca gactatgaaa accaaatgct tcgtgatgcg agcttgagca ttattcgtgc
    21421 cctcaagatt gaaggtggat gtaatgttca gctagctctt gatcctaaca gcttcaagta
    21481 ttatgttatc gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt ctaaagcgac
    21541 aggatatccg attgctaagt tggctgccaa gattgcagta ggtttgacct tggatgaggt
    21601 tataaaccca gttacaggtt caacctatgc catgtttgaa ccagcccttg actacgtagt
    21661 tgctaagatt ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc gtctcggtac
    21721 acaaatgaag gcgactggag aagtcatggc aatcggtcgt aacatcgagg aatctcttct
    21781 caaggcctgc cgctcccttg aaattggggt gcaccacaat gaaatacctg aacttgcagc
    21841 agtttctgat gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc gtctcttcta
    21901 cgtatcagaa gcaattcgtc gtggctacac acctgaagaa attgcagagc ttacaaaaat
    21961 tgatatcttc tatcttgata aactcttgca tatctttgaa attgagcaag aattgggtgc
    22021 tcatccacaa gatctagaag ttttgaaaac agccaaactt aatggttttt cagaccgtaa
    22081 gattgctgaa ctctggggaa cgactgatga tcaagttcgc caacttcgct tggaaaacaa
    22141 gattgttcca gtttataaga tggtagacac ttgtgcggca gagttcgact ccgaaacgcc
    22201 atatttctat tcaacctatg gttgggaaaa tgaatctatc agatctgata aagaatctgt
    22261 acttgtccta ggttcaggtc caatccgtat tggtcaaggg gttgagtttg actacgcaac
    22321 cgttcactct gttaaggcta tccaggcagc tggttatgaa gctatcatca tgaactcaaa
    22381 cccagagacc gtttcaacag acttctctgt atcagataag ctttactttg agccattgac
    22441 attcgaagat gttatgaacg tcattgactt ggaacaacca aagggagtta tcgttcagtt
    22501 cggtggtcaa acagccatca accttgcgga gccattggca aaagcaggtg tgaccatcct
    22561 tggtacacag gttgctgacc tagatcgtgc cgaagaccgt gacctcttcg agcaagctct
    22621 caaagaattg gatattccac agccaccagg acaaacagct accaatgaag aagaagcagc
    22681 tcttgcagct cgcaagattg gcttcccagt tcttgtccgc ccatcttatg tacttggtgg
    22741 acgtgccatg gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc gaactgctgt
    22801 taaggctagt ccagaccacc cagttcttgt cgactcttat atcgttgggc aagagtgcga
    22861 agttgatgcc atttcagatg gtaaaaatgt actcattcct ggtatcatgg agcatatcga
    22921 acgtgctggt gtccactcag gtgactcaat ggctgtttac ccaccacaaa ccttgtcgca
    22981 aaaggttcag gagaccatcg cagactacac caaacgctta gcaatcggtc ttcactgcct
    23041 tggaatgatg aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta ttgaggtcaa
    23101 tccacgtgcc agccgtactg ttccattcct atctaaggta accaatattc ctatggctca
    23161 agtagcgacc aaactcattc ttggtcaaag tttatcagaa cttggctacc aaaatggact
    23221 ttaccctgaa agcacccgtg ttcatatcaa ggcacctgtc ttctccttta ccaaactagc
    23281 taaggtagac agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta tgggttctga
    23341 tgctactttg gaaaaagctc tctataaagc ctttgaagct tcttatctac acttgccaac
    23401 ttttggtaat gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct tgaacttggc
    23461 tcgtcgtttc caaaacattg gttatggaat ccttgcgaca gaagggacag cagccttctt
    23521 tgctagccat ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg ataaggatat
    23581 cccaagtttt gtacgcaaag gaagaattca agctatcatt aacacagtag gaacaaaacg
    23641 aactgctgac gaagatggtg agcaaattcg tcgttcagcc attgaacacg gggtgcccct
    23701 cttcacagcg ctagatacag ctaatgccat gcttaaggta cttgaaagtc gtagctttgt
    23761 tacagaagcg atttaaatag aaaaataaga tatagcagac tgaatttaga acagtacaca
    23821 ggaatactaa aatatttcta gaaattaatt tgaattttct aattgatttg ttcgcatctt
    23881 atttcaatct actatagaaa aaagtcttta aaattataaa acgcatcata tcaaggtttt
    23941 tcaaaaacct tgatatgatg cgttttattg tgggaatatg tatttcattt tctactaaaa
    24001 ttatgttttt gaataacctc tatcttagta gtttgtataa tccccctcaa tcagtttttg
    24061 cgataagctt taatgctatg actataccac tcttgcattt cttttgatgg tggtgtcata
    24121 taatcgccat acatctgggt taaaaattgg tcatattttt tgggaacagg caacatacgg
    24181 ccctcaaact cagttaaaat cagttcttta aaggtatcaa ctgggaagat ttctttcatc
    24241 ccttccttac cgatcccaac tcctccttca tattgaggaa tgttggttac agcatttttg
    24301 actagttgat caattttctt gtaaaagtag cgaggattga caaatcggag agcgtaccag
    24361 ctacataatc taagaaaatc ttttagtttg ctatcaccgt gaactgctcg tgattttttg
    24421 atgtaagcta gttgacgaag ggccacatac ttatagctct tgtcgacaat gctcaagtct
    24481 gtaaattgat caattgggaa gacatcgatg aaaaggctgg tatcatgacg cttgtactta
    24541 acatggtctt ctataacagt agaagtatcc aaaatcgatg cgaaattatg gaagtaccaa
    24601 gaagatgtat cgtaggaaag aaccttgtag cgagggtgat tttcttcttc aataatcttc
    24661 agtaaacgct cataatcctc acgataaagg gaaatatcaa tatcatcatc ccaaggaatc
    24721 atacctttgt ggcggatggc tccaagcatg gttccataac tgagaaaata aggaatatca
    24781 tgtttcttac aagtctcatc aatatagtcc agcagggcta gttgaatttc tttaatttct
    24841 tttttttcta aatattgcat cctaatcctc caatttataa gcgtgaaatt catgactgta
    24901 gaagcgtttt tcttctggtg gtagggtcat ataatctcca taaaattgtg tcaaaatagt
    24961 atcaaatttt tcaggtgcag gaaggcttaa attctcaaag ggtaaatcga ttgttttatc
    25021 aaaggtagca cttgggaaga cttccttttc cttaaatttt gaaggaataa aagccatata
    25081 ctgcccattt tcacgactat atttttgaat ttctttctcg attttatttg caaaataacg
    25141 aggagaaacc agtcgaagga gcaaccaaaa ggctgttcgt atccaatctt ttaaaaggct
    25201 atccttatag acaatatttt tatgtttact gaaagacagc agtttgaagc tttctagttt
    25261 ataacaagta tcaatgacct taggatcatc aaagcgatcc atagggaaaa tatcgataaa
    25321 gataccagac tcataggttt ttgtatttcg agtatcaata attttagtcg tactgtcggt
    25381 tatcttgata aagttgttaa agtagttctt atcagtttct aaggatagga gcttatactt
    25441 gcttttttcc ttttgaaaaa tgttaataaa tcgttggtag tcttctctag gcatggataa
    25501 atcaatatcg tcgtcccaag ggataaagcc ctcatgtcga accgccccaa tcagagtacc
    25561 gtagttaata atatagttga tattgtgctt tttacagaga gtatcaatat aattcaaaat
    25621 ttctaattca atttgtttgg catcttcaac ggttagttgt ttcattttaa actcctaaga
    25681 ttttttaaat ttatttttta aggctaggac atggtttaaa aattcataga aaatgctatc
    25741 ttttgtgaag acaagtagac taatataaga gatagctgat agcaagacaa tcaaaccagt
    25801 attaatcaaa aatggcaaat taatgaccat atccacagga tacacgaaat taatcaggaa
    25861 ataaattgct acaaaggaaa gtgaaaagag agagtatcga acagtatagc taaagatatg
    25921 tcccaagtgg atgagttgtt ttctatggat gaaaatgata tagaaaacaa gtagagaagc
    25981 ctctgataac atagttgtca gtaagtagta ttcgggagcc acgatatggt tgaaaaagag
    26041 gagactattc aagcccaaat tgagtagccc agcaaagact gtatagactg tgatacgttt
    26101 ttcatagcca ttggtaaaga gaatttggga accaagaatg gtatctaagg ccaggataat
    26161 cgtacgaaaa gcgaagagag aggtcaagat gtcgcctccg atatattttt cactaccgta
    26221 aagtaggatg gcatttggtc ctaaaaccat gagtccaaaa ctcagtggaa tgataaagaa
    26281 gttaaagatt cgactacctc tattaaccag agaaacatag gcttctttgt ctcctttccc
    26341 cagatagtaa ctgagacgag gcacactcac tccaattgca cctgttacaa ccccagctat
    26401 aacggtcaca attcgctgag ctatggtata gtaactaacg ttgacatcaa tccctgtttt
    26461 aacgaggaag aggcgatcta aaaaagtgaa gagcatattg gcattggcaa agactaacat
    26521 ggctgtcaga gggagaaaga gtggtttaaa atcacttagg tgaatcttaa caagtttgat
    26581 gtctctttta atccaaaaat aactaatcag gtagttaatc agcgtcgata aactcatcac
    26641 aagtgtatag acaacaatat cgtgttcatt tttaacaaat aagaaaatag agaccagcat
    26701 caggatacgg atgaaggcag ttttgtaaaa gagaaaactg taattttcca gagcttcatt
    26761 gacccattcg attgaaaaaa tctgggcaat gagttgaatc cccataacaa ggtagacctt
    26821 tttgacgatt ggattatcag taaagaagag aggataggct aggatataga cagcagtggt
    26881 caaaatcgta caagcgatgc acaaataaaa aagactagaa aaggttctgt taagatcttt
    26941 tttgttatcc ttgacattac tgatagccct taaaccgtag ttatagacac cataagttgc
    27001 aaagggcaag aaaaatgaca aaatagtgtc gactgagttg aagtaaccat agtcagttcg
    27061 gtccaagaca cgcgcgacat aggttccagt taggatggga aaaataatat tcaagacacg
    27121 aattcccatg taagatagag catttaattt tatacttttc attcaattta cctcgttttt
    27181 cattatatca taaagttagc taataagaaa tgaagggcag taagtcaagt aatcactttg
    27241 aagtttcaaa tcttaagttt taagttttct ttaaggaaag tatattattc tgaaggactc
    27301 taaaatttcg cagccattta ttagtaattg ctacagaatt cctagtcatt actagaaatg
    27361 gactagtttc tttgaataat agaactgcat aattctccta ttctagaagg ggaggaccag
    27421 tatttctttt atgataggac tagattgtgg tataatagag agaataagtt tttttagtaa
    27481 gacaaaggag aaaatagatg atttatgcag gaattcttgc cggtggaact ggcacacgca
    27541 tggggatcag taacttgcca aaacaatttt tagagctagg tgatcgacct attttgattc
    27601 atacaattga aaaatttgtc ttggagccaa gtattgaaaa aattgtagtt ggtgttcatg
    27661 gagactgggt ttctcatgca gaagatcttg tagataaata tcttcctctt tataaggaac
    27721 gtatcatcat tacaaagggt ggtgctgacc gcaatacaag tattaagaaa atcattgaag
    27781 ccattgatgc ttatcgtccg cttactccag aggatatcgt tgttacccac gattctgttc
    27841 gtccatttat tacacttcgc atgattcagg acagtatcca acttgcccaa aatcatgacg
    27901 cagtggacac agtggtagaa gcggttgata ctatcgttga aagtaccaat ggtcaattta
    27961 ttacagatat tccaaatcgt gctcaccttt atcaaggaca aacacctcaa acattccgtt
    28021 gcaaggactt catggacctt tatggatctc tttctgatga agagaaggaa atcttgacag
    28081 atgcatgtaa aatctttgtg atcaaaggaa aagatgtggc cttggccaaa ggtgaatact
    28141 caaatctgaa gattacaacc gtaacagatt tgaagattgc aaaaagtatg attgagaaag
    28201 actagtaaaa tgattaatca aatttatcaa ctaactaagc ctaagtttat caatgtcaaa
    28261 tatcaggaag aggctattga ccaagagaat catatcctta tccgtcccaa ctacatggct
    28321 gtctgtcatg cggatcagcg ttactatcag ggaaaacgtg atcccaagat tttgaataaa
    28381 aagcttccaa tggcaatgat tcacgagtca tgtggaaccg tcatttctga cccgaccgga
    28441 acctacgagg ttggtcaaaa agttgtcatg attcccaatc agtctcctat gcagagtgat
    28501 gaagaattct atgaaaacta catgacaggg acccatttct tgtctagtgg atttgatggc
    28561 tttatgagag agtttgtttc tctccctaaa gatcgtgtgg tggcttatga tgctattgaa
    28621 gatacggttg cagccattac agagtttgtc agtgtgggca tgcacgctat gaatcgtcta
    28681 ttgactcttg ctcatagcaa gcgggagcgg atcgccgtta ttggagatgg aagtttagct
    28741 tttgtggttg ccaatattat caactatact ttgccagaag cagagattgt ggttattggt
    28801 cgtcattggg aaaagttgga actcttctca tttgccaaag aatgctatat tacggataat
    28861 attcctgaag agttggcctt tgaccatgct tttgaatgtt gtggtggtga tggtactgga
    28921 ccagctatta atgacttgat tcgctacatt cgtcctcagg gaacgattct catgatggga
    28981 gttagcgaat ataaagtcaa tctcaatact cgcgatgcct tagaaaaggg cttgattttg
    29041 gttgggtcat ctcgttctgg tcgcattgat tttaaaaatg ctatccaaat gatggaagtc
    29101 aagaaatttg ccaatcgtct taaaaatatc ctttatctag aagaacctgt aagagaaatt
    29161 aaagatattc atcgtgtctt tgcaaccgat ttaaacacag cctttaaaac agtgtttaag
    29221 tgggaagtat aagtactgga ggttaattgt ggagaaaatc attaaagaaa aaatttcttc
    29281 cttacttagt caagaagagg aagtcctcag tgttgaacaa ctgggtggaa tgaccaatca
    29341 aaactatttg gccaaaacaa caaataagca atacattgtt aaattctttg gtaaagggac
    29401 agaaaagctt atcaatcgac aagatgaaaa gtacaatctt gaactactaa aggatttagg
    29461 cttagatgta aaaaattatc tttttgatat tgaagctggt atcaaagtaa atgagtatat
    29521 cgaatctgcg attacgcttg attcaacgtc aatcaagacc aagttcgaca aaattgctcc
    29581 aatattacaa actattcata cgtctgctaa ggaattaaga ggagaatttg ctccttttga
    29641 agaaatcaaa aaatacgaat ccttgattga agaacaaatt ccttatgcca actatgaatc
    29701 tgttagaaat gcagtcttct ccttagagaa aagactggct gacttaggtg ttgacagaaa
    29761 atcttgtcat atcgatttgg tgcctgaaaa ctttatcgaa tcacctcaag gacgacttta
    29821 tttgattgac tgggaatatt catcaatgaa tgatccaatg tgggatttgg ctgccctctt
    29881 tttagagtct gaattcactt cccaagagga agaaactttc ttatctcact atgagagtga
    29941 ccaaacaccg gtttctcatg aaaagattgc tatttataaa attttacaag atactatttg
    30001 gagtctatgg actgtctata aggaagagca aggtgaagat tttggtgact atggtgtgaa
    30061 tcgttaccaa agagctgtta aaggtttggc ttcttatgga ggttcagatg aaaagtaaaa
    30121 acggagttcc ttttggcctt ctctcaggta ttttctgggg cttgggtcta acggttagtg
    30181 cttatatctt ttcgattttt acagatttgt caccctttgt ggtggctgca gctcatgatt
    30241 ttttgagcat ctttatctta ctagcttttc tcttggtaaa agaagggaaa gttcgcctct
    30301 caattttctt aaatattcgc aatgtcagtg ttatcatcgg agccttgcta gcaggcccta
    30361 tcggtatgca ggccaatctt tatgcagtta agtatatcgg aagttcttta gcttcatctg
    30421 tatcggctat ttaccctgcg atttcagttc tattggcttt cttctttttg aagcacaaga
    30481 tttcgaaaaa tactgtattt gggattgtct tgattattgg agggattatt gcccagacct
    30541 ataaagttga acaggttaat tctttctaca ttgggattct ttgtgctttg gtttgtgcta
    30601 ttgcatgggg aagtgagagt gttcttagct cttttgccat ggaaagtgaa ttgagtgaaa
    30661 tcgaagccct cttaatccgt caagtaactt cgttcttgtc ctatcttgtg attgtgctct
    30721 tctctcatca gtcatttact gcagtagcca atggacaatt gctaggtctc atgattgttt
    30781 ttgcagcctt tgatatgatt tcctacttgg cttattatat cgctatcaat cgcttgcaac
    30841 cagccaaggc tacaggcttg aacgtgagct atgtagtatg gacggtcttg tttgcagttg
    30901 ttttcttggg tgcaccgcta gatatgctga ccattatgac gtcacttgtc gtcattgctg
    30961 gagtttatat tattattaaa gaataaagga gattcgtgtg aaagccatca tcttagcagc
    31021 gggattggga actcgcttgc gtcctatgac tgaaaatacc cctaaagcct tggttcaggt
    31081 taatcaaaaa cctttgattg agtaccaaat tgagtttctc aaagaaaaag gaatcaatga
    31141 catcatcatc attgttggtt atcttaaaga acaattcgat tacttgaaag agaaatacgg
    31201 tgttcgtctc gttttcaatg ataaatacgc tgactacaat aacttttact ctctctatct
    31261 tgtaaaagaa gaattagcca atagttatgt tatcgatgcc gataactatc tctttaaaaa
    31321 tatgttccgc aatgatttga cacgttctac ttattttagt gtctatcgtg aagattgtac
    31381 caacgaatgg ttcttggtct atggagatga ctacaaggtt caaaacatta ttgttgatag
    31441 caaggcaggt cgcatcctta gtggtgtatc cttctgggat gctccaacag cagaaaaaat
    31501 tgttagcttt atcgataagg cttatgcaag cggcgaattt gttgatctct attgggacaa
    31561 tatggttaag gataacatca aagagctaga tgtctatgtt gaagaattag aaggcaatag
    31621 catttatgag attgatagtg tccaagacta tcataaatta gaagaaattc ttaaaaacga
    31681 aaattaaaag cttccaacat ctgacaaaat agtcggatgt ttttttgatt ttttacgaac
    31741 ttttacgaat agatagatga gtagaaaaag aaatggagtt atttatgaaa atcacaaact
    31801 atgaaatcta taagttaaaa aaatcaggtt tgaccaatca acagattttg aaagttctag
    31861 aatacggtga aaatgttgat caggagcttt tgttgggtga tattgcagat atatcaggtt
    31921 gccgtaatcc agccgttttt atggaacgtt attttcagat agacgatgcg catttgtcga
    31981 aagagtttca aaaatttcca tctttctcta ttttagatga ctgttatcct tgggatttga
    32041 gtgaaatata tgatgcgcct gtacttttat tttacaaggg aaatcttgac ctcctgaaat
    32101 tcccgaaggt agcggtcgtg ggcagtcgtg cttgtagcaa acagggagct aaatcagttg
    32161 aaaaagtcat tcaaggcttg gaaaatgaac tggttattgt cagtggtctg gccaagggca
    32221 ttgacacagc agctcatatg gcagctcttc agaatggcgg aaaaaccatt gcagtgattg
    32281 gaacaggact ggatgtgttt tatcctaaag ccaataaacg cttgcaagac tacatcggca
    32341 atgaccatct ggttctaagt gaatatggac ctggcgaaca acctctgaaa tttcattttc
    32401 ctgcccgtaa tcgcatcatt gctggacttt gtcgtggtgt gattgtagca gaggctaaga
    32461 tgcgttcagg tagtctcatt acgtgtgagc gagcaatgga agaaggacgc gatgtctttg
    32521 ctattcctgg tagcatttta gatggactat cagacggttg ccatcatttg attcaagaag
    32581 gagcaaaatt ggtcaccagt gggcaagatg ttcttgcgga atttgaattt taaaaatgac
    32641 ctaagctaga attctaagaa aaaatcaatt ttaagagaaa atgaacccaa catttccata
    32701 ataaaacgca tattagcaag tttttaacac ttgataatat gcgttttttc taagtggatt
    32761 agtagagtag aggatttttc tcatataata ctcttcgaaa atctcttcaa actacgtcag
    32821 cttccatctg caacctcaaa acagtatttt gagctgactt cgtcagtctt atctacaacc
    32881 tcaaagcagt gctttgagca acctgtggct agcttcctag tttgcgcttt gattttcatt
    32941 gagtataagg gaaagtatag tgaattgaaa taagatgtga acaactctat caggaaagtc
    33001 aaattaattt atagaaatat tttagcagcc aaggtgcact gttatagatt caatacacta
    33061 taatttagtg taattgagaa aggagaaatg attgtgattg atgttggcta ggttatgttc
    33121 aatgattcct accgtctcaa atcttgtcag taaggaaaaa taaattcttc aaaagtagag
    33181 attacaaggc ttgtttaaga aagaattcaa agaccttgac aaataaaaat aaaatggtta
    33241 ttataaaaaa tggtctgaaa tagatgatga tacttttcga aaatcttttt acgtcagctc
    33301 agctttgcct tgctgtgttt tgagcaagct acggttagct tccgagtttg attttcattt
    33361 actagaaatg aaactgatga gagatatcag tagacatttg agtcaggata ttatggaaaa
    33421 tgataaaaag agctcgtgag attggcatat cagactacta aagtattgag tttgttagga
    33481 ttttagcgac tagttagctg ggaaaggaag atatttgtga caaataataa actgtattcg
    33541 ttgatagaat ttagaaataa aatatatgaa gaattagaac tttccagaag tgatttagcg
    33601 attttactat gtgccatgct tatcgcctct atcggattaa atatggattc gactcccgtg
    33661 attattggag ccatgttaat ctctcctttg atgacaccta ttctgggagt ggggctctct
    33721 ctagctatat ttgattttaa attgttaaga aaatctttta aaatattagc tattcaaatt
    33781 cttgccagtt taatagcttc aacactttat ttttatcttt ctcccatttc gtatgctagt
    33841 tcggaaattg ttgctagaac ctctccgact atttgggatg ttctcattgc ttttgtagga
    33901 gggatagcag gtattattgg tgctaggaaa aaagagacca ataatattgt tcctggtgtt
    33961 gctattgcaa ccgccttgat gcctcctctt tgtacagtag gttatgctat tgcttctgct
    34021 aatctaaaat ttatcatagg ctcctcttac ctattcctca tcaattgtag ctttattgtc
    34081 attgcgactt atataggtgt taggttgatg atggttaaga aacattattt taaagataat
    34141 gaagaagact ctaaaatgcg taggattttg cttctagttg ctgttttgct gatgattccg
    34201 agtttcatct ctgcaacgac tttagtgaga gaaacgttga aaaaagagtc ccttaagaaa
    34261 tttatatcag agcagtttca ggggcataat attttgaaaa aaacctattc taaaaagact
    34321 cataccctaa agctaaccat ttcaggaaat tatttgacag aagaagaact cgatatgatt
    34381 tcaagtaaga gaggtgacta tggtttaagt gatgtttctg ttcaagtttc acaattgtct
    34441 gattcagaac aacttagtaa ggaagaactg gtggagtatt tcttccagta tatcaaggat
    34501 aaggaagcaa aagaaaagga aaaagctaat aagttttata cagagtctga ggagcaataa
    34561 tttcttgaga atagctggtt tctctcgtga gtcttctatg tatatcaaag gaagactgag
    34621 gttttaagta taaaactttt cttctattat agtagctaag tcttgacagg gttcaaaaaa
    34681 tggtttacac tttataaagt ttattacttt gaaaaggtgt gatactgtgg ctacggcaac
    34741 aaaaaagaaa aaatcaacag ttaaaaaaaa tctagtcatc gtggagtcgc ctgctaaggc
    34801 caagacgatt gaaaaatatc taggcagaaa ctacaaggtt ttagccagtg tcgggcatat
    34861 ccgtgatttg aagaaatcca gtatgtccgt cgatattgaa aataattatg aaccgcaata
    34921 tatcaatatc cgaggaaaag gccctcttat caatgacttg aaaaaagaag ctaaaaaagc
    34981 taataaagtt tttctcgcga gtgacccgga ccgtgaagga gaagcgattt cttggcattt
    35041 ggcccatatt ctcaacttgg atgaaaatga tgccaaccgt gtggtcttca atgaaatcac
    35101 caaggatgca gtcaaaaatg cttttaaaga acctcgtaag atcgatatgg acttggtcga
    35161 tgcccaacaa gctcgtcgga tcttggatcg cttggtaggg tattcgattt cgcctatttt
    35221 gtggaagaag gtcaagaagg gcttgtcagc aggtcgcgtt cagtccattg cccttaaact
    35281 catcattgac cgtgaaaatg aaatcaatgc cttccagcca gaagaatact ggacagttga
    35341 tgctgtcttt aaaaagggaa ccaaacaatt tcatgcttcc ttctatggag tagatggtaa
    35401 aaagatgaaa ctgaccagca atgacgaagt caaggaagtc ttgtctcgtc tgactagtaa
    35461 agacttttca gtagatcagg tggataagaa agagcgcaag cgcaatgctc ctttacccta
    35521 taccacttca tctatgcaga tggatgctgc caataaaatc aatttccgta ctcgaaaaac
    35581 catgatggtt gcccaacagc tctatgaagg aattaatatt ggttctggtg ttcaaggttt
    35641 gattacctat atgcgtaccg attcgactcg tatcagtcct gtagcgcaaa atgaggcggc
    35701 aagcttcatt acggatcgtt ttggtagcaa gtattctaag cacggtagca aggtcaaaaa
    35761 cgcatcaggt gctcaggatg cccatgaggc tattcgtccg tcaagtgtct ttaatacacc
    35821 agaaagcatc gctaagtatc tggacaagga tcagctcaag ctatataccc ttatctggaa
    35881 tcgttttgtg gctagccaga tgacagcggc cgtttttgat accatggctg ttaaattgtc
    35941 tcaaaatgga gttcaatttg ctgccaatgg tagtcaggtt aagtttgatg gttatcttgc
    36001 catttataat gattctgaca agaataagat gttaccggac atggttgttg gagatgtggt
    36061 caaacaggtc aatagcaaac cagagcaaca tttcacccaa ccgcctgccc gttattctga
    36121 agcaacactg attaaaacct tagaggaaaa tggggttgga cgtccatcaa cctatgcgcc
    36181 aaccattgaa accattcaga aacgttatta tgttcgcctg gcagccaaac gttttgaacc
    36241 gacagagttg ggagaaattg tcaataagct catcgttgaa tatttcccag atatcgtaaa
    36301 cgtgaccttc acagctgaaa tggaaggtaa actggatgat gtcgaagttg gaaaagagca
    36361 gtggcgacgg gtcattgatg ctttttacaa accattctct aaagaagttg ccaaggctga
    36421 agaagaaatg gaaaaaatcc agattaagga tgaaccagct ggatttgact gtgaagtgtg
    36481 tggcagtcca atggtcatta aacttggtcg ttttggtaaa ttctacgctt gtagcaattt
    36541 cccagattgc cgtcataccc aagcaatcgt gaaagagatt ggtgttgagt gtccaagctg
    36601 tcatcaggga caaattattg agcgaaaaac caagcgtaat cgcctattct atggttgcaa
    36661 tcgctatcca gaatgtgaat ttacctcttg ggacaagcct gttggtcgtg actgtccaaa
    36721 atgtggcaac ttcctcatgg agaaaaaagt ccgtggtggt ggcaagcagg ttgtttgtag
    36781 caaaggcgac tacgaggaag aaaagattaa ataagaggag gggcccgaaa gtaaatttca
    36841 ggctcctttt ggttagaact tgacaaaata catcatttta tgcgaaacta gaagaagatt
    36901 attttatact caatgagaat caaagagcaa attagaaagc tagtcgcagg ttgctcaaag
    36961 cactactttg aggttgaaga tggaagctga cctggtttga agagattttc gaagagtatt
    37021 aactaggaga agttatgcgt attatctatc taattattgg ttttttatcg ctgaccttgg
    37081 ctattgttgg ggttgtttta cccttgttgc ctacaacacc tttccttttg ttgtctattg
    37141 cttgtttctc cagaagttcc aagcgattcg aagattggct ttatcatacc aagctctatc
    37201 aagcatatgt agctgatttt cgtgagacca agtctattgc gcgtgaacga aagaaaaaaa
    37261 tcatcgtctc tatctacgtc ttgatgggaa tttctattta ttttgcacct cttttaccag
    37321 tcaaaatcgg tctgggtgct ttgaccatct ttattactta ttatctcttc aaggtcattc
    37381 cagacaaaga atagttaaaa cagtagttat ttgccttgat aaaattgaaa gcatattcat
    37441 aacaatatga tataataaaa ttgaagtaat attcaaggag aatcaaatga tttacgaatt
    37501 ttgtgctgaa aatgtgactt tacttgaaaa agcgatgcag gctggagctc gtcggattga
    37561 actctgtgat aatctagcag ttggtgggac aacacccagc tatggagtga ctaaggcagc
    37621 ggttgaactg gcagctaact acgatacaac catcatgacc atgattcggc cacgtggtgg
    37681 tgactttgtc tataatgacc tagaaattgc tatcatgcta gaagacattc gtttgactgc
    37741 tcaggctgga agtcaagggg ttgtatttgg agctttaact gctgataaaa agttggataa
    37801 gcctaatctg gaaaagttaa ttgctgcatc aaaaggaatg gaaattgtct ttcacatggc
    37861 ctttgatgaa ctaagtgatg aagatcaacc ggaagctatt gactggctca gtcaagccgg
    37921 tgtcactcgt atcctaactc gtgctggtgt gtctggcgac tccttagaaa aacgttttgt
    37981 tcactatcac agaattttgg agtacgctaa aggtaaaatt gaaattctac caggtggggg
    38041 gattgacctt gaaaaccgtc aaacctttat cgaccaggtg ggggtaacac aattgcatgg
    38101 tactaaggtt gttttttaaa aaatagaaag gaactgctag ctttgggtag cagttttcac
    38161 ttatgtttga aatttttaaa tcctatcaat ttaatcaaga aaaggctcat gattatggtt
    38221 ttatagaaaa tagcgaagtc tggacatata gttgccagat tttgcaaggt gactttgtca
    38281 tgactgtgtc catcactgct gataatgtga actttcaagt ctttgaccaa gagactggtg
    38341 acctctatcc tcacgtttat atggaaagca tgaggggaag ttttgtcgga aatgtccgtg
    38401 aggcttgtct ggagattctt taccagattc ggaaggcttg ttttgatgtg caagatttta
    38461 tctgtcatca gactaagcgt atcatgactc aagttcagga aaagtatgga aaccagttgg
    38521 agtatctgtg ggaaaaatcg cctgatacag ctgtattgcg ccatgaaggc aatcaaaagt
    38581 ggtatgccgt cttgatgaaa atctcttgga ataagctgga aaagggcaga gaaggacaag
    38641 tggaagcagt caacctcaag catgaccaag tagctaattt gctttcacaa aaggggattt
    38701 atccagcctt ccatatgagc aagcgctact ggattagtgt gtcccttgat gatactttat
    38761 cagatgaaga agtactggaa ttgatagaaa aaagttggaa cttaacctct aaaaaatgaa
    38821 atattttaat aattttcatg aactttcaat tagctaaata ttctttactg aagagatttt
    38881 tagaaaatat aggatttacc acactagagg aatatggtgc catcttcaaa tacctgattg
    38941 agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat gacctcggaa
    39001 tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt gaagggacta
    39061 tcaatggtat tagggagcga gctgaaaatg ctgctttgga agaaattgca gtggctctca
    39121 atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag accatcaata
    39181 cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa gccgtcgttg
    39241 gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt aaaaatcctc
    39301 tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattctgctt ggaaaattat
    39361 ctggtcgcca tgcttttgtt gagaaactga gagaattggc cctagatttt acagaagagg
    39421 atatcaaacc actctttgct aagttcaagg cactggtcga taagaagcaa gaaatcacag
    39481 atgcagatat tcgagctttg gtagctggaa ccatggttga aaatccagaa ggcttccact
    39541 ttgatgattt acaacttcaa actcatgcag ataatgacat tgaagcgctc gttagcctag
    39601 ccaatatgga tggtgagaaa gtcgaattta atgcgacagg gcaaggttcc gttgaagcaa
    39661 tctttaatgc tatcgataag ttctttaacc aatctgttcg tttggtgtcc tacactatcg
    39721 atgcggtaac agatggaatc gatacccagg atcgggtttt ggtcactgtt gaaaacagag
    39781 atacagaaac catctttaat gcagcagggc ttgattttga tgtgttgaag gcttctgcta
    39841 ttgtctatat aaacgctaat acctttgttc aaaaagagaa tgcaggtgag atgggacgca
    39901 gtgtttctta ccacgatatg cctagtgtgt aaaggagaag gctatggcaa agaaaatagt
    39961 agctctagca ggagacggaa ttggcccaga aatcatggag gttggtttag aagttctgga
    40021 ggctctagct gaaaaaacag gttttgacta tgagattgac agacgaccgt tcggaggtgc
    40081 agatattgat gcagcatgac ctcccttacc tgatgaaacc cttaaggcaa gtagggaagc
    40141 agatgctatc ctactagtag ctatcggtag tcctcagtat gatggagcag tggttcgccc
    40201 tgaacaaggc ctgatggctc tccgtaagga actcaatctt tacgctaata ttcgtcctgt
    40261 aaaaatcttt gacagtctca agcatttgtc actactcaaa ctggaacgaa ttgctggtgt
    40321 agactttgtc gtggtgcgtg aattgacagg cgggatttac tttggagatc atattcttga
    40381 agagcgcaat gcgcgtgata tcaacgacta tagctatgag gaagtggagc ggattattcg
    40441 caaagccttt gaaattgcaa gaaatcgcag aaaaatcgtt actagtatcg ataagcaaaa
    40501 tgttctagcg acctcaaaac tctggcggaa agtagctgag gaagtcgcac aggatttccc
    40561 agatgtaacc ttggaacatc agctggtaga ctcagctgct atgcttatga ttaccaatcc
    40621 tgctaagttt gatgttattg taacggagaa tctttttgga gatattttat ctgatgaatc
    40681 aagcgtctta tctggtacac ttggggttat gccatcagcc agtcattctg aaaatggacc
    40741 aagtctctat gaacctattc acagttcagc acctgatatt gcaggtcaag gaattgccaa
    40801 tcctatttcc atgattttat cagtttccat gatgttgaga gatagtttcg gacgttatga
    40861 ggatgcagag cgtatcaaac gtgctgttga gacaagtctg gcggcaggaa ttttaacgag
    40921 agatatagga ggtcaggctt caacaaagga aatgacggaa gctattattg caaggttatg
    40981 aagttagacg aaaaaattac tctagtcctt ttgatttgga atgtcatcat tttcttgatt
    41041 tatggtattg acaaatctaa ggcaaggaga agagtttggc gcatccctga gaaaatctta
    41101 cttattttag cctttacttt tggtggtttt ggtgcctggc tagcaggaat catctttcac
    41161 cacaagactc gaaaatggta ctttaaaata gtttggtttc ttgggatggt gaccacacta
    41221 gtagccttat attttatttg gaggtaatgg atggcagggt cttcgaggga atacgctgct
    41281 tgggctctag cggactatgg ttttaaggtc gtgattgcag gatctttcgg tgacattcat
    41341 tacaataatg aactcaataa tggcatgttg ccaatcgttc agcctagaga ggttagagag
    41401 aaactagccc agctaaaacc aaccgaccag gtaactgtgg acttggaaca acaaaaaatc
    41461 atctcaccag ttgaagaatt caccttcgag atagatagcg agtggaaaca taaactccta
    41521 aatagtttgg atgatatcgg tattaccttg cagtatgaag agttgattgc tgcttatgaa
    41581 aaacaacgac cagcctactg gcaggattag aaaaaataga aaaggagata tagtaaactg
    41641 aaataagatg taaacaaatg aattggagct taacatccat ttccagcaat tttttagaaa
    41701 ctacagtgga ctattctgga ttcaacacat tataaaatta tgacaaaaca cattcacaag
    41761 aaggctacga cattttaaaa ggtgagggcg gatgtatcgt ttgccctact aaagttggtt
    41821 acattatcat gaccagtgac aaggcaggac ttgagcgtaa gttcgcagcc aaagaacgta
    41881 agcgtaacaa accaggtgtt gttctctgcg gtagcatgga tgaactttgc gctttagcgc
    41941 aactcaaccc agaaattgaa gcattctact aaaaacattg ggatgaagat attcttcttg
    42001 gttgtatcct tccttggaaa ccagaagcct ttgaaaaact caaagcatac ggggatggcc
    42061 gtgaagaact tatgactgat gtacgtggta ctagctgttt tgttatcaag tttggaaaag
    42121 caggtgaaca attggctgcc aagctttggg aagaaggtaa aatggtctac gcctcatctg
    42181 cttcaatgac aaaacgattg aaactcgcta tgagcaaggt gtaatggtgt ctatggtcga
    42241 taaggacggc aaactcatcc cagaacaagg aggagcacgt tcaacttcac cagctccagt
    42301 tgtgatccgt aaagggcttg acattgatat agtaaaatga agtaagagca ggacaaatta
    42361 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
    42421 ttcaatccac tataaaatca tgatgcacct gtcagatact tttaactcat gggactaccg
    42481 tcaggttgag tattattagg atagagaaga agtctagtgt taaggacatt acagctcata
    42541 atactaggct tttttataga aattcttttc tttttctata ggatatggta ttctatgtag
    42601 aaaatatatg ttaataagta atgccaatat ttaaacatca ttagtaaaag gagttagatt
    42661 gatgaataaa agaaaagtta gtttagaaga tttttataaa tggtatagtc taaataaaga
    42721 agagttatta aataaggcaa ctgttggtga aaagtttaat gataaattaa aagaagagtt
    42781 tctccaggaa tggcctttgg ataggatttt aacaatgtca atcgatgaat atgtaatagg
    42841 aaagggacag caaaataagt ctttatgcta cgctcttgag aagggaaaat acaaaaatct
    42901 atttcttgga atttctggtg gctcagcttc aaaatttggt atttattgga ataaaaaaac
    42961 aaacaaatat aaagatcaag ctaataatga gatttcagag ttggatcagc gattttcaaa
    43021 attaaaatca gatttgtatg aaattatcaa agaaggtatt cgttttaact ttgaaaatcc
    43081 tatttttgat atgaaaagat caacaaatga atttattggt cgttctgcta tggtgacaaa
    43141 attactttgt atctatactg agggagatcc tttctttggt gtaaatatta atagtcagaa
    43201 agaattttgg aaccactttg tttctcagac aaatcaaggt ggaccttatc tgcaaaatca
    43261 taaaataatt gaactgatgt ccaaaactta tcctgagttg gagccatcga aattaggaac
    43321 tatgcttttt gagtattcta agctttttat ggaaaataag gaagacaata gtacaatgga
    43381 ttcatcaaac aattttcgtc atcaattaac tcaatctcta ttaaagtctc caaaccttat
    43441 ccttcgtggt gctcctggca caggaaagac ttatcttgct aaagaaattg ccaaagaatt
    43501 aacggatggc aacgaagatc aaatcggatt tgtacaattt cacccatcat atgattatac
    43561 ggattttgta gaaggtttaa gaccagtatc aaatggggat ggagctattg agtttaggct
    43621 acaggacggt atttttaaag atttttgtca gaaagcaaaa gaaacccaat tgattggagg
    43681 acaagataat tttgatgagg cttgggattc ttacttagaa tatataaatg ttgctgaaga
    43741 aaaagaatat ataacaaaaa catcttactt atctgttaat agtagacaaa atttgtcagt
    43801 aaattatgat agtggtgttc caggatggtc actacctagc aaatatgttt acgagttgta
    43861 taaagataaa aattataata agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga
    43921 aacattgaga aagagatttg gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga
    43981 taagaaattc gttttcatca tcgatgaaat caatcgtggg gagatttcta agatttttgg
    44041 cgaactcttt ttctctatcg accctggcta tcgtggtgaa aaaggaagtg tttctaccca
    44101 atatgcaaat ctacacgaaa ctgatgaaaa gttctatatc cccgaaaatg tttacatcat
    44161 cggaactatg aatgatattg atcgttcagt ggataccttt gattttgcta tgcgtcgtcg
    44221 ttttcgtttt gttgaagtta ctgccgaggg tcaagttggc atgttggata aagagctgaa
    44281 tatccatgca gaagaagcaa aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt
    44341 tcaggaatta aacagtcatt atcatattgg accaagttat tttcttaagt tgaaggatgt
    44401 agattttgac tatgaattac tctggtccga ttatattaag cctctcctag aagactactt
    44461 gcgaggttct tatgatgagg ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac
    44521 aaataatgag caaaaagatc aggcagtagc tgatgacaat gaaagcgatg aaaacgatga
    44581 tgcggattac tgataatcaa cacaagatta ttaaagaaaa atttgttgaa gaatatccta
    44641 aactaagcaa tcttctttta gacagaacct tggaaagtct atcccaagat gaacgtattt
    44701 tcatttttcc aaatgatttg actcatactc cagatttgga taaaaaacaa aagattttgg
    44761 aaacgatcaa tcaggaaatc aagacaggaa atgtgattgg ttttcttgga tatggtcagg
    44821 aaagattaac gatttcctca cgattttctg atgagagtaa tgaccatttt ttgcattatc
    44881 tcttaaacaa ggttcttcat atcaatctca ctagtttaga tgttgctttg tctcgtgaag
    44941 agaggcttta tcaacttttg atgtatctct tccccaagta tctacaagct gctattcgaa
    45001 aaggtcttta taaggaatat catcgatttt ctcataacga cagtcatgtt aagggagtga
    45061 ttgatgtaag aaaccatctc aagaaaaatc ttcctttcac gggaaatatt gcctacacaa
    45121 cgagagagtt cacctatgat aatcccctca tgcagttggt ccgtcacact attgaataca
    45181 ttaagaatca gaaaagcatt ggtcaagggg tactagataa tctctcaact agtcgtgaaa
    45241 acgtatctga aatcgtgcgt gtaacgccct cttataaact agctgatcgt gctaagatta
    45301 ttcggggaaa tcaatctaaa cctatacgtc atgcatactt tcacgagtac agaaacttac
    45361 aagaactttg tctgatgatc ctaaaccaag aaaagcacgg tttagggtat caagatcaaa
    45421 aaatctatgg tattctcttt gatgttgcct ggctttggga agagtatgtt tacaccttgt
    45481 tgccaaaagg ttttgtacat cccagaaata aggataagac ggatggaatt tcagtatttt
    45541 ctgttgggaa acgaaaagta tatccagatt tttatgacag agaacgaaag attgttctag
    45601 atgcaaaata taaaaaactg gaattgactg aaaaaggaat caatcgtgag gacttattcc
    45661 agctgatttc ctattcttat attttaaaag ctgagaaggc tggacttgtt tttccgagca
    45721 aggacaaggt tattgataat gagatgggaa acctagcagg ttatggagct ttgttgaaga
    45781 aatggtctat ccaaattcct cagaagtctt catcttatag tgcattttgt aaaatgatgg
    45841 aaaattcaga ttatagtgca ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag
    45901 cgattattga tgaagaagtg gggagaaaat aatttcccct ctttctttta tttttaacac
    45961 aagtaaaacc cgaacaatat atttcaattc ataaaataat ttgacaaaaa ctgtactttg
    46021 gtttataata aattaaggaa acgtcggaaa agacgtagtg atgcgagagc ataggtaggt
    46081 cattacaaaa gaaacgagac atcgatatgt taaatgaatt tccaattttt gattacgaag
    46141 atattcaatt gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg
    46201 tcactttagg aaatcacacc tttaaactac ctgttgtgcc agcgaatatg cagacgattt
    46261 tggatgaaaa tgtagcagag caactggcta aaggtggtta cttctacatt atgcaccgtt
    46321 ttgatgaggc aggacgcatt ccttttatta aacaaatgca cgatcaaggg ctcattgctt
    46381 ccatctctgt cggtgttaag gactatgagt atgattttgt tagccagctc aagactgatg
    46441 ctcctgagta tatcactatt gatattgctc atggtcatgc ggatagcgtg atttctatga
    46501 ttcaacatat caagaaagaa ttgccagata cctttgtcat tgctggaaat gtgggaacac
    46561 cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc tactaaggtc ggaatcggtc
    46621 ccggtaaggt ttgtatcacc aaggttaaga ctggttttgg tacaggtggt tggcagttgg
    46681 ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc
    46741 gtactcacgg tgatattgct aagtctatcc gcttcggtgc tagcatgatc atgattggtt
    46801 ccctctttgc aggacacatt gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt
    46861 tcaaagaata ttatggttca gcctcacaat atcaaaaagg tgcttacaaa aatgtggaag
    46921 gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga cactttaact gagatggaac
    46981 aagaccttca aagtgctatt tcttatgcag gtggacgtca ggttgctgac cttaaacacg
    47041 ttgattatgt gatcgtgaaa aactccatct ggaatgggga tgcttcccac taagacgggg
    47101 tctttgacca aaaaacttgt tattagagca aatttctgtt ataataaaac aagtttccac
    47161 ccttagtgta atggatatca cgtaagattc cggttcttga gatgggggtt cgattccctc
    47221 agggtggatg taaacatcct aaaaagcctt taatagggct tttttcttta tcctgaccca
    47281 aatttgccgc taaaactgag aatctctgtc taaagaattc ccaaatgctt tccagtcccg
    47341 ttttagagtg actcaggggg ctttttttga tataataaaa aggactgtta tcagttagaa
    47401 agaggttggt atgaaagaat tacaaactgt actaaagaat cattttgcaa tcgaatttgc
    47461 agacaaaaat ttactggaaa ctgcctttac tcatacgagt tatgccaatg agcaccgcct
    47521 cttaaaaatt tcacacaatg aacgcttgga atttttagga gacgctgttc tacagttatt
    47581 gatttcagaa tatctatata aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact
    47641 ccgtgctatg attgtccgtg aggagagttt agctggtttt gcgcgtgatt gccagtttga
    47701 ccagtttatc aagttgggta aaggggaaga aaaatcaggt ggtcgcaatc gtgacaccat
    47761 tcttggtgat gcctttgaag cctttcttgg tgcccttctt ttggataagg atgtggccaa
    47821 ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt gaagcaggcg aatttgagat
    47881 gattacagac tataaaaccc atctccaaga gttacttcag gtcaatggtg atgtggctat
    47941 tcgttatcag gtgatttctg aaacagggcc tgctcacgat aaggtctttg atgtagaagt
    48001 tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca
    48061 ggaagctgcc aaaaatgccg ttgagaaggg gctggattca tgtatttaaa ggaaatcgaa
    48121 attcaggggt tcaagtcttt tgctgataag accaaggtcg tttttgacca aggtgtgacg
    48181 gcagttgttg gacccaatgg atctggaaag tccaatatta cagaaagtct gcgttgggct
    48241 ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt catctttgct
    48301 ggaacagaaa gtcgcaaacc gctcaattat gcttctgtag ttgtgactct ggataatcat
    48361 gacggattta tcaaggatgc aggtcaagaa atcagggtgg aacgccatat ctatcgtagt
    48421 ggagatagcg aatacaagat tgacggcaag aaagtccgtc tgcgtgatat tcatgacctt
    48481 ttcttggata caggtttggg acgagattcc ttctctatta tttcccaagg gaaggttgag
    48541 gagattttta attccaagtc tgaggaacga cgagctattt ttgaagaagc tgctggagtt
    48601 ttaaaataca agactcgcag aaaagaaacc gagagtaaac tgcagcaaac tcaggataat
    48661 ctggaccgct tagaggacat tatctacgag ttggataatc aaatcaagcc tcttgagaag
    48721 caagctgaga atgcccgtaa atttctagac ttagaaggtc aacgcaaggc tatttacttg
    48781 gatgtattgg ttgctcaaat caaggaaaat aaggcagaac tagagtcgac agaagaagag
    48841 ttggctcagg ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa attagaagaa
    48901 gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc caaagaccaa
    48961 ggcagtttga tggacttgac tagtctgatt agtgatttag aaagaaaatt agccctatcg
    49021 aaactggagt ctgagcaagt ggccttgaat caacaggagg cacaagctcg tttggctgct
    49081 ttggaggata agagaaattc actcagcaaa gaaaagtctg ataaagaaag ctctttagct
    49141 ctgttagagg gaaatctagt ccaaaataat caaaaactca atcgtttaga agctgaattg
    49201 ctggctttct cagacgatcc tgatcagatg attgagctct tacgtgaacg ctttgtagct
    49261 cttttacaag aagaagcgga tgtctcaaac cagttgaccc gtattgagaa tgagttggaa
    49321 aatagtcgtc agctttctca aaaacaagca gatcaactag aaaagctgaa agagcaatta
    49381 gctatagcta aagagaaggc tagtcagcaa aaggaagagc ttgaaactgc caaggagcag
    49441 gttcagaaat tattggctga ctaccaagct attgccaagg agcaagagga gcagaaaact
    49501 tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg ataatctcaa aaacaagcag
    49561 gccagagctc aaagtttgga aaatatcctg agaaatcata gtaactttta tgcaggtgtt
    49621 aagagtgttc tccaagaaaa agatcgccta ggtgggatta ttggtgcagt cagtgagcat
    49681 ctgacctttg atatgcatta tcaaactgcc ctagaaattg cgcttggagc gagtagccaa
    49741 catatcatcg tagaagatga agagtcggca accaaggcta ttgacttcct taaacggaac
    49801 agagccggtc gtgcaacctt tcttcctttg accactatca aggcgcgtac gatttctagt
    49861 cagaaccaag atgctatcac tgtaagccca ggtttccttg ggatggcaga tgagttggtg
    49921 acttttgata ctagactgga agccattttc aagaacttgc tagctacgac ggctatcttt
    49981 gatgccgtag aacatgcgcg tgcagcagct cgccaagttc gttatcaggt tcgtatggtg
    50041 acattggatg ggacagaatt acgcacgggt ggttcctatg cgggtggtgc caatcgccaa
    50101 aataacagta ttttcatcaa gccagaactg gagcaattac aaaaagaaat tgctgcagat
    50161 gaagcaagct tgcgttcaga agaagcggct ttgaagacct tacaagacca gatggctaca
    50221 ttgacagaaa gattagaagt catcaaatct caaggagaac aggcacgtat tcaggagcaa
    50281 ggcttgtccc tcgcttatca gcaaactagt cagcaagttg aagaactgga aactctttgg
    50341 aaactccaag aagaggaaat agatcgtctt tccgagggag attggcaagc ggataaggaa
    50401 aaatgccaag atcgtcttgc tgcaatcgcc agtgacaagc aaaatctgga agctgagatt
    50461 gaagagatta agtctaacaa aaatgccatc caagaacgct atcaaaactt gcaggaagag
    50521 ctagcgcaag ctcgtttgct taagacagaa ctgcaagggc aaaaacgtta tgaagttgct
    50581 gatattgaac gcttaggcaa ggaattggac aatcttgatt ttgaacaaga ggaaatccag
    50641 cgccttcttc aagaaaaggt tgataatctt gagaaggttg atacagaatt gctcagtcaa
    50701 caggcggaag aagccaaaac tcagaaaaca aatctccaac aaggtttgat tcgcaagcag
    50761 tttgagttgg atgatattga aggtcaactg gatgatattg ctagtcattt ggatcaggct
    50821 cgccaacaga atgaagagtg gattcgcaag caaacacgtg ctgaagccaa gaaagaaaag
    50881 gtcagcgagc gcttgcgcta tttacaaagt caattaacag accaatatca gattagctat
    50941 actgaagctc tagaaaaggc gcatgaattg gaaaacctca atctggcaga gcaagaggtg
    51001 caggatttag agaaagctat tcgctcactg gggcctgtca atatagaagc tattgaccag
    51061 tacgaagaag ttcacaatcg tctggatttc ctaaatagcc aacgagatga tattttgtca
    51121 gcgaaaaatc tgctccttga gaccattaca gagatgaatg atgaggtcaa agatcgcttt
    51181 aaatcaacct ttgaggccat tcgtgaatcc tttaaagtga ccttcaaaca gatgtttgga
    51241 ggaggtcagg cagacttaat cttgactgag ggagacttgt tgacagctgg ggttgagatt
    51301 tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa
    51361 gccttatcag ctcttgcttt gcttttttct atcattcgag ttaagactat cccatttgtc
    51421 atcttggatg aggtagaggc cgcgctggac gaagccaatg ttaaacgttt tggggattac
    51481 ctcaatcgat ttgacaagga cagccagttt atcgtcgtaa cccaccgtaa gggaaccatg
    51541 gcagcggctg attctatcta tggagtgacc atgcaagaat cgggggtctc aaaaattgtt
    51601 tcggttaagt taaaagattt agaaagtatt gaaggatgac aattaaacta gtagcaacgg
    51661 atatggacgg aaccttccta gatgggaatg gacgctttga tatggatcgt ctcaagtctc
    51721 tcttggcttc ctacaaggaa aaagggattt actttgcggt ggcttcgggt cggggatttc
    51781 tgtctctgga aaaattattt gctggtgttc gtgatgacat tattttcatc gcggaaaatg
    51841 gcagtttggt agagtatcaa ggtcaggact tgtatgaagc gactatgtct cgtgactttt
    51901 atctggcaac ttttgaaaag ctgaaaacgt caccttatgt agatatcaat aaactgctct
    51961 tgacgggtaa gaagggttca tatgttctag atacggttga tgagacctat ttgaaagtga
    52021 gtcagcatta taatgaaaat atccaaaaag tagcgagttt ggaagatatc acagatgaca
    52081 ttttcaaatt tacaaccaac ttcacagaag aaacgctgga agctggagaa acttgggtaa
    52141 acgataatgt ccctggtgtc aaggctatga caactggctt tgaatctatt gatattgttc
    52201 tggactatgt cgataaggga gtggctattg ttgaattagc taaaaaactt ggtatcacaa
    52261 tggatcaggt catggctttt ggagacaatc ttaatgactt acatatgatg caggttgtgg
    52321 gacatcctgt agctcctgaa aatgcacgac ctgaaatttt agaattagca aagactgtga
    52381 ttggtcacca taaggaccag tcggttatag cttatatgga gggcttataa tggcagatat
    52441 aaaattaatc gcattggact tggatggtac cttgctgact actgataaaa ggctgacgga
    52501 tcgcaccaag gcaactttga aagctgcgag tgatcgtggt atcaaggtcg tattgacaac
    52561 tggtcgtccc ttaaaagcca tggacttctt tctccatgag ttagggactg acggccatga
    52621 agatgagtat accattactt ttaatggtgg attagttcag aaaaatacag gagaaatcct
    52681 tgataaaaca gtcttttcat atgatgatgt ggcacgtttg tatgaggaaa cagagaaatt
    52741 atcactgcct cttgatgcca tctcagaagg aacagtttat caaatccaat cggaccaaga
    52801 aagtctttat gccaaattca atccagcttt gacttttgtt ccagttgact ttgaagacct
    52861 gtctagtcaa atgacctaca acaaatgcgt gactgccttt gctcaagaac ccttggatgc
    52921 agccattcag aagatttctc cagaattgtt tgaccaatat gaaatcttta aatcacgtga
    52981 aatgttgcta gaatggtcac caaagaatgt tcataaagca acaggtttgg caaaactaat
    53041 tagccatctt ggaattgatc aaagtcaagt gatggcctgt ggtgacgagg ccaatgacct
    53101 ctctatgatt gaatgggcag ggctcggtgt tgccatgcaa aacgctgttc ctgaagtaaa
    53161 ggcagccgca aatgtagtga cgccgatgac caacgatgag gaagctgtcg cctgggctat
    53221 cgaagaatat gtgctaaagg agaactaaga tatgggatta tttgaccgtc tattcggaaa
    53281 aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc
    53341 tgaagatgtt gatcctacct tcacagaagt tgaagaagtt tctcaagaag aagctgtgct
    53401 tgaagaaagt caggattcag agccagctgt aggggtttct caagaagaaa tagaagaatt
    53461 accagaggaa gagaagcttg agcacgaagg aactatagaa gaaaataatt ctgaagttct
    53521 tgaagcagaa aggcctcaaa cagaagaaac tgttcaggaa aaatatgacc gcagtcttaa
    53581 gaaaactcgc acaggtttcg gtgcccgctt gaatgccttc tttgctaact tccgctctgt
    53641 tgacgaagaa tttttcgagg aactggaaga actgttgatt atgagtgatg ttggtgtcca
    53701 agtcgcttct aacttaacgg aggaactacg ttacgaagcc aagcttgaaa atgccaagaa
    53761 acctgatgca cttcgtcgtg tcatcattga gaaattggtt gagctttatg aaaaggatgg
    53821 tagctacgat gaaagcatcc acttccaaga taacttgaca gttatgctct ttgttggtgt
    53881 gaatggtgtt gggaaaacaa cttctatcgg aaaactagcc caccgctaca aacgagctgg
    53941 taagaaggtc atgctggttg cagcagatac cttccgtgcg ggtgcagtag ctcagctagc
    54001 tgaatggggc cgacgagtag atgttccagt agtaactgga cctgaaaaag ctgatccagc
    54061 cagcgtggtc tttgatggta tggaacgtgc cgtggctgaa ggtatcgata ttctcatgat
    54121 tgatactgct ggtcgtctgc aaaataagga taaccttatg actgagttgg aaaagattgg
    54181 tcgtattatc aaacgtgttg tgccagaagc accacatgaa accttcttgg cacttgatgc
    54241 atcaacaggt caaaatgccc tagtacaggc caaagaattt tcgaaaatca cacctttaac
    54301 gggaattgtt ttgactaaga ttgatggaac tgctcgagga ggtgtggttc tagccattcg
    54361 tgaagaactc aatattcctg taaaattgat tggttttggt gaaaaaatcg atgatattgg
    54421 agagtttaac tcagaaaact tcatgaaagg tctcttggaa ggtttaatct aatcagaagc
    54481 aaaaatcctg caaggcataa acttgcagga aattttttta ttcgaaacga ccatcttgac
    54541 gataggcgat atctggttgc caagtccatt tggcaccgaa tttttcaagt aggtcaaagc
    54601 tggcttgagg tcccatgctt ccagctttat agtcatgaag tggggcacca ttttcagccc
    54661 agagctcttc aatacggtca atcaacttcc atgatgcacc aacttcatcc cagtggctaa
    54721 agttagttga gttgttattt aggacatcat aaatcaattt ctcgtatggt tctggagaag
    54781 caccagttgc agtcgcatct gtacggtaat caagtgagtt aggagccaag ttaaattctt
    54841 ctcctacttg cttcccattt aggctaagag agaagccttc tgttggttga atatagatgg
    54901 tcaaaatatt tggagcaagt ggttctccaa agatagaatc catttgttta aagacgatgt
    54961 tgacatgagt tcctttttca gtcagtcgtt tacctgtacg gaaaaagaaa ggaacactac
    55021 ggaatcgatc gctgtctaca aagaaggcac cagatgtaaa ggtttcagtt gttgattctg
    55081 gattcacatt tggctcgcta cgataagaga tgtatttcat gccatcaatc ttaccagagc
    55141 ggtattgccc acggataaag tgttctttga gttcttcatc agttggatga tagaggtttt
    55201 taaagacctt aatcttttca gcacgaatct cgtcttttgt gaagattgct ggtttgtcca
    55261 tggcgaggag cgaaagaagt tgtagagtgt ggttttggac catgtcacgg agggcaccgg
    55321 attggtcata gtagccacca cgttcttcta cacccaagcg ctccgcaaag gtaatttgaa
    55381 cattgtcgat aaaatccttg ttccaaacgt tttcaaaaat caagtttgca aagcgaactg
    55441 caaagatgct ttggatcatt tccttaccaa gataatggtc gatacggaaa atttgttctt
    55501 cgtcaaatgt tgctaggagt tcgtcattca acttgcttgc agttgcgtaa tctgtaccaa
    55561 atggtttttc aacgatcaag cgctcaaaac ctttgccatc gacaatgttt tcagatttga
    55621 ggtgtttggc aatggttcca aagaactgag gtgccataga caagaagaag agcttattgt
    55681 gttcagcttg gtatttttca ttaagctcag cttgtaattg acgcaaagca atataatgtt
    55741 ccgaatcatt gacatcatgg ctttgatagt agaagtggct agcaaattct tgggcttgct
    55801 cggtactatc tgccaaatca aggatggact cgacaactac agattcaaaa tattccttac
    55861 tccaaggtct acgggcagtt ccaataacgg caaagtgctt ggaaagattg ccggattgat
    55921 atagtctaaa aagggaaggg tagagcttgc gtttagccag gtctccactc gcaccgaaaa
    55981 ttgtaacaat aaccttagat gacatctagc tacctaattt ctatttttat tcctagtctt
    56041 gctaggtatg aggaaacctc atttcataaa cttaattcta acataatttt ccgaaaaatc
    56101 aaaaattcca atacgaggta gaaaaactgc aaggaaatcc ttacagtttg agtttagacg
    56161 tttaagacct tatctaagaa ctctttcaga cgagggtgtt gtgggttatc aaagatttgg
    56221 tcaggtgttc cgtcttcaag gaactcgcca tctgcagtaa agataacgcg gttggcaacc
    56281 tgacgagcaa atcccatctc atgggttacg ataatcatgg tcatgccttg ctcagccaat
    56341 tccttcataa cgttaagtac gtctccaacc atctcagggt caagggcaga agttggttca
    56401 tcgaagagca tgatgtctgg attcattgct aggccacgag cgatggccac acgttgtttt
    56461 tgaccacctg ataggttatc tggattggca ttagctttat ctgctagtcc aaccttttca
    56521 agcaactcca ttcccaattc ctcagcttct tccttagtca tcaacttgtg ctcaatagga
    56581 gcaaaggtga tgttgtccaa tacagacata tgagggaaga ggttgaagtg ttggaatacc
    56641 atgccgatat tttcacggac gtggtcaaca ttggttgttt tttcagttaa atcatagccg
    56701 ttcacagtga tgtgaccgct agtgacttct tctaaaagat tgaggctacg gaggaaagtt
    56761 gacttaccag aacctgaagg accgatgata caaacaacat ctccttcata gaacttagtc
    56821 gtaattcctt ttaggacttc attttttcca tagtgcttgt gtaaatcatt tacatcaatt
    56881 tttaattttg ccattaacga atcctctttt ctaagcgttt cgctagtcta gtcaaaagtg
    56941 tgataattac aagatagaag atagcaagga ttgcatacat cttgaaactt tggtagttac
    57001 gagcaatgat aatcttacca gtttggaaga gttcaaccaa accgatagca gatacgatag
    57061 ttgtatcttt aagagcgata acgaattggt tgacaaagtt tggcaacatc aatttagttg
    57121 cttgtggcaa gataatctta cgcatggttt ttccataaga gatacccaag cttcggctgg
    57181 cttccatttg gccaactgga acggcctgaa taccaccacg aacgatttca gcgatataag
    57241 cagccgcatt gagtgagagg gcaatggttc cagctacaaa gtcgttaatt gggctttgtt
    57301 ggcctgtgat agactcgatg aagtttggaa ttccccagaa gatgaaggct gcaagaatca
    57361 tcaatggaat accacgaata acgtcaacga aaatctcaga gatgacgcga agagatttgt
    57421 atgggctaac gctaaacata ccgaagataa ttccgatgac aatggcaata gcaaatgaga
    57481 taagagctag agcaagagtg ataccaagac cgctaaggag ttgtttgtag ttgttttgaa
    57541 gcaagcccca gagcgttgtt tcgtcaacag tacttgttga agcagttgaa gattcgctag
    57601 ctaggtattt gtcaagaatc ttttggaatt caccgtttgc tttaaggttt gcaagtccgt
    57661 tgttgaacat ttcaatcagt tctggatttg ctcctttttt aacggcaaag gctgtttcac
    57721 cgattggagt tccagagatt ggagttttca atttttgacc ttggctgata gaatatttga
    57781 gaacaggttc atcatccata acggcatcaa tggcaccagt gtttaaactg tcatacattg
    57841 aagaaccatc agcaaaggtt ttgattttgt aaccgtattt gctttgattt tctgttagga
    57901 aggtttgaga agcagttccg tttttaacac cgactgtctt tccttttaga tcttcataag
    57961 aagcaatatt gcttgattct ttgacaccaa gaatggtatt agcagtgtag tatgattctg
    58021 agaagtcaaa agttgcctta cgagcatctg tgacagacat accagcaatg ataccatcgg
    58081 cttgaccagc ttggacagca ctgatagcag catcaaaacc agggttggtg atttcaattt
    58141 caaaaccttg gtctttagcg attgccttaa tcaattccat atcaatacca gtgtattggt
    58201 tgcttgaatt ttggaaaaca aaaggtgcaa aagaagaatc gctggcaatg atatatttag
    58261 ccttaacagg aatagctttt aatcctgcga gagtagttgt agttggcact gctgaagatg
    58321 atgaagcagt ccatttcttg ataattttat caagactacc atcttttttc atttcagcca
    58381 aggcttggtt aaattcagta accaggtgct cgtatttact tccttttttc acaccgaaag
    58441 caaaacttcc tacagcttca ccatccattt caatatggag gtcttgacct tggttaatgg
    58501 catattcgat aacaggtttg tcatccatca tggcatcgat ggcaccagca ctcaagctgt
    58561 tgttcattaa atcaccagtg tcaaatgttt taatagtaaa gccgtattta tctttgattg
    58621 tttcaaggaa acgttgagcg gcagttccgt ttttaacacc aacggttttg ccagttaatt
    58681 ggtcgtactt gctaattttg tgtgactttg tagtagcaat gacaactttt gtatcatagt
    58741 aagtatcaga catggtgaag actttttcac gttctttagt ctttgtcatc cctgccatga
    58801 tagcgtcggc ttgcccagct tgaaccgcat tgactgctgc gtcaaatcca ggataggaca
    58861 tctgaatgtt ccagccttta atctcagcga ctttgttaat aatgtcaaca tcaattcctt
    58921 tataagtttg atctgaatct ttaaactcaa aaggtgcata ggcggtatca gaaacaatct
    58981 taatcgtttc tgctttggca atacctaatg agaaaattgg gaataaaatt agcaaaaatg
    59041 ctagaaattt tttcttcatt tttagtctcc ttttccgaat attctctcat tatatcagaa
    59101 aaagtaaaaa aaggcaaatt tttatatttt tcgtgtcaga aaatataaca ttgatttttc
    59161 cttttctttc ttgaattgct attaaaaatt gctataataa tactatatat agaagaaaag
    59221 aggacgggga tatgaagaac aaaagaatat ttaaagactt ccaagcttca aaaatgaatt
    59281 taaaccttta cacaagcccc ttgttagcct ttgtttttgt cttcatagga gagtttgtgg
    59341 cttatacttt atatggtatt agtttgttag ctctcatcgg acttgctaga aattttggag
    59401 aggctggtca aaatcttgca agctacttgc agaccttgca tcagagcttg acggataaaa
    59461 caagtgactt tcgtttaatt ttaggattac tggcctttgg ttttattctt aacactgtgt
    59521 tcagatggac aagaaaagtt gagaaaagac ctattcgaac cttgggattt tatagagaga
    59581 attgcctcag caatcttctg aaaggattta gtctaggcct ggcacttttt cttctgacct
    59641 tgttaagttt agtggtctta ggtcaatatc gtttggaatc cattcacttg aatccttatt
    59701 atcttgcctt tgtcgtcttt actatcccat tttggatttt acaggggaca gcagaagaag
    59761 tggtggcccg tgcttggcta cttcctcaat tggcctcaag aaccaatcta aaactagcta
    59821 ttcttatatc tagcctgttc tttaccctgc ttcatatggg caattctggc ctcacccctc
    59881 tatctctagt aaatctcttt ttattcggag ttgccatggc tctttacctt ctcaaaactg
    59941 atacagtttg gggtgttgca ggtattcatg gtgcttggaa ttttgctcag ggtaatctct
    60001 ttgggatttt agttagtggt caaccgtcag gaacgtctct gatgaccttt ttaccacaag
    60061 gcaatcaaga ttggctatca ggtggttctt ttggcataga aggttccatt atgacaagtc
    60121 tggtattact actgctgatt gtctatcttg ctaataaatt aaagaaagaa aatgaaagga
    60181 tgtgacttcg gtccgtcctt ttcttcgtga aaatactata agtatgctaa aataggaata
    60241 gcacatggag agaggattct tatgatcaat cacattacag ataatcaatt taaactagta
    60301 tcaaaatatc aaccatcagg agatcaaccc caagctatcg agcagttggt ggataacatt
    60361 gaggggggag aaaaagctca gattctgatg ggggcgactg gaacagggaa gacctatact
    60421 atgagtcagg tcatttctaa agtcaataaa ccaactctgg ttattgccca caataaaact
    60481 ctggctggtc agctctatgg ggagtttaag gaatttttcc ctgaaaatgc agttgagtat
    60541 ttcgtatcct actatgatta ttaccagcca gaggcctatg tcccttctag cgatacctat
    60601 attgagaagg atagttctgt caatgacgag attgacaagc ttcgccactc agctacctca
    60661 gcccttttgg agcgtaatga tgttattgtc gtggcctcag tctcttgtat ctatggtttg
    60721 ggttcgccca aggaatacgc tgatagtgtc gttagtctcc gtcctggtct agagatttct
    60781 cgtgataaac tcttgaatga cttggtcgat attcagtttg aacgcaatga tattgatttc
    60841 caacgcggaa gatttcgcgt tcgtggggat gtggtagaga ttttcccagc ttcccgagat
    60901 gaacatgcct ttcgagtaga attttttgga gacgaaattg accgtattcg tgaagttgag
    60961 gctctgacag gtcaggtgtt gggagaagtg gatcatttag cgattttccc agcgacacac
    61021 tttgtgacca atgacgacca catggaagtt gccattgcaa agattcaggc cgagttggaa
    61081 gaacaattag ctgtctttga aaaggaaggt aaactgcttg aagcccagcg tttgaaacag
    61141 cggacagagt atgatatcga aatgttgcgt gagatgggct ataccaatgg ggttgaaaat
    61201 tattctcgcc acatggatgg acggagcgaa ggagagcctc cttatacgct tctcgacttc
    61261 ttcccagatg atttcttgat tatgattgac gagagtcata tgaccatagg gcaaatcaag
    61321 ggcatgtaca atggagaccg ttcgcgtaaa gaaatgctgg ttaattatgg tttccgtttg
    61381 ccgtctgctt tggacaatcg tcctctccgt cgggaggagt ttgagagtca cgttcatcag
    61441 attgtttacg tttcagcgac acctggtgac tatgaaaatg aacagaccga gacagtgatt
    61501 gagcaaatca ttcgtccaac gggactcttg gatccagagg tggaagtccg tccgactatg
    61561 ggacagattg atgacctctt gggtgaaatc aatgcccgcg ttgaaaaaaa tgagcgtacc
    61621 tttatcacaa ctttgaccaa gaaaatggca gaggacttga ccgactactt caaggaaatg
    61681 ggtatcaagg ttaagtacat gcactcggat atcaagacct tggaacggac ggagattatc
    61741 cgtgacctgc gcttgggtgt ctttgatgtc ttggtcggaa ttaacctgct ccgtgaagga
    61801 attgacgttc ctgaagtgag cctcgtagct attctcgatg ctgacaagga aggtttcctt
    61861 cgcaacgaac gtggactcat ccagactatt ggacgtgctg ctcgtaacag tgaaggccat
    61921 gtcatcatgt atgcagacac ggttacccag tctatgcaac gtgctatcga tgaaactgcc
    61981 cgccgtcgga aaattcagat ggcctataat gaagagcatg gtatcgtacc acagacaatc
    62041 aagaaagaaa tccgtgacct gattgctgtg accaaggcag ttgctaagga agaggacaag
    62101 gaagtcgaca tcaatagcct caacaaacaa gagcgcaaag aactcgtcaa gaaactagaa
    62161 aaacaaatgc aagaagccgt cgaagtactt gactttgaac tggcggctca gatccgtgat
    62221 atgatgttgg aagtcaaggc cttggattag gggaatagta tgatttattt aagaaagtta
    62281 aagagagaag atttgatgtc tttatgggaa atggcttatt cacaacttaa tccagtttgg
    62341 aaacagtatg atgctcccta ttatgatgat tatcagtatt tttcaaattt taaagaattc
    62401 gaactacaaa aatcagaatc cattttaagc aactcaaatc gccttggtat ttttgttgat
    62461 gataaactag ttgggactgt ttcgcgttat tgggtatgta aacaaacaag atggatggaa
    62521 ttgggaattg gtatttatga taaaaaattc tggaacactg gtattgggaa agttgctatg
    62581 ttgcagtgga tagataggac gtttcaggat tacttggagt tggagcatct gggtttgaca
    62641 acttggtcag ggaatcttgg tatgatgaaa cttgctgaaa aattaagaat gaaaaaagaa
    62701 gctcatattc caaaagttcg ttattatcaa ggtaaatatt ttgatagtat taaatatggt
    62761 attttgagag aagactggga gaaaacaaat gacggttatt atcaaatcaa tggaaactcc
    62821 tgaagagata gaaggtaagc cccttgttca ctggcaaacg tggagagagg cttatgatgg
    62881 ccttttgcct gcagaatttc aggagacaat gacattagaa agatgtcgat tctttagtca
    62941 aaagtatcca gaaaatacat tgattgcgat ggatggtatg aaggtagttg gttttatcag
    63001 ttatggcaac tttcgtgatg agactattca agctggcgaa attattgctt tatatgtttt
    63061 aaaagactat tatggaaaag gtatcgcaca aaagttaata aaagcagctt tgattgctct
    63121 taatcatttt tctgaaattt tcttatgggt attgaaagat aataagcgcg caattgcttt
    63181 ctatcaaaaa atgggcttta cttttgatga acaagaaaag atacttgaac ttggaaagcc
    63241 cataaaggaa aaacggatgg tattctattc taaataattt taaaaagtag aagctaatgg
    63301 tactggtatc aagtctaaaa atttaataaa ttagaaagtg agtaaattta tgtctcgagc
    63361 acaattaacg attttaacaa atatttgtct gattgaagat ctcgaagctc agcgcgtggt
    63421 gatgcagtat cgcgctcctg aaactaatcg ctggtctggt tatgcctttc caggaggcca
    63481 tgtagaaaat ggcgaatctt tcgcagagtc tgtcattcgt gaaatctatg aagaaacagg
    63541 gttgactatc caaaatcctc aacttgtcgg cattaaaaat tggccactag atacaggtgg
    63601 gcgctatatt gtcgtttgtt ataaggcaac tgagttctct ggtacccttc gctcttcaga
    63661 tgaaggagaa gtttcttggg tgcaaaaaga ccagattcca aacttggatc tggcctatga
    63721 tatgctacct ttgatggaga tgatggaagc atcggacaaa tctgaatttt tctaccctcg
    63781 ccgtacagaa gacgattggg aaaagaaaat tttctaatcc tttactaaat aacctagctg
    63841 atccaaggcc tcctcgatat agtggaggtc ttgttgtgtt tcggcttcga ctaggtggta
    63901 atggacacca tctgtcaatt cagataaagg tttaaaatca gaatgctcga cttgttctag
    63961 aaaatgttga acgtctcggc ggcaagacag tttaagcaag gtttcaattt ctccataaac
    64021 gggatggtca atcaaagtat tctggacatg cccaccatta tcgacaatag caaggagttc
    64081 ctgaccgatt tcttcaactt catgtttcac tttgaaaagt ttgtgaacat aaggattggt
    64141 atcaatttgc ttatagatgt agccacgatt ggtggatagg ataggagcgc catcggctct
    64201 caaaattgca atgtcctgca caatgacctg acgtgtgaca tgaaaatgtt ccgccaaact
    64261 ttggccatta agggctttag gagcttcttt caagagttgg agcagggctt gtttgcgatc
    64321 ttttgtcata gcttttcctt ttaacggcgt tttcgaagca ctttatagac agctagtgct
    64381 aatgtatagt ctaccatact atggataatt gtgccaaatc caactagtac aaatagaaca
    64441 tagaacatgt tttctacatt ggtacccgaa gttgcgtaaa aaaggacaca ggctaatact
    64501 tcagcaaggg catgaacaac agccaaaaca aaattgaaaa cccaggaaga ttttggttta
    64561 tctagggtat cggggaattt ttgtaggtaa agagatccta aagcaccaaa agatatatgg
    64621 gaaaaagccc gaaaaactat aaccatggga tagccagcca tcaaaaatcc aaaactagag
    64681 gctaggatga caaaaactgc catcaagggc gacaagaaca tggctataaa aatagcgatg
    64741 tggctcccca aagtatagga agcaggtgga atgacaatct tgaaaggcat aacaattgga
    64801 atcaaaatcg caatagccgt taaaagggct gtcattgtca taaattgtgt ctttttccgt
    64861 gtattcacaa gaatctcctt tttaactgca tatacactag tatggtacaa taaaccagac
    64921 aataaagcaa gaatttactt gggtttatag atcatttttt agttaaaagt tatagtagat
    64981 ggaaactaga atagtccacc tctacttcta aaacattgtt agcgatttga ctgtcctgat
    65041 cgatttgtcc tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt
    65101 atagagcaaa atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt
    65161 ttgtagtcgt ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga
    65221 atttgttgag ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa
    65281 taggaagaag attcctccaa ggacaaagat agtatttgtc aaggaaccaa gggctccagc
    65341 taaaatcaga ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat
    65401 caaaatacgt gggacgatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg
    65461 agagaagagg tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc
    65521 catcaaaaat ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac
    65581 aggaatatga acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct
    65641 cagaaagtgt atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg
    65701 ttttttcatc gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc
    65761 ctcgtccgtg gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt
    65821 aggtttctaa tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca
    65881 tagcaggagc tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca
    65941 tgttgtccgc aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga
    66001 taaataaatc tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct
    66061 tcatgacatc caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa
    66121 actctgtagc agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac
    66181 tgactaaatc tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg
    66241 ccatagtttt cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat
    66301 ttcttcttta gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg
    66361 atctgctgaa atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag
    66421 actttttcgt gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc
    66481 aatcagatga atagtgggat tccattcctt gactagggat atgattttgg gtgtcttttt
    66541 aaggaacaaa acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct
    66601 taaaaattct tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg
    66661 agtgtagtca gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg
    66721 catttctatt agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg
    66781 ctctggcttc agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa
    66841 agtctctgtg ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct
    66901 atcgatagct tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac
    66961 aaaaataagc ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta
    67021 tagtttcaaa ctataaagcc atataaaatt taagaaagga ctctaaaagc cttaaaaaca
    67081 gagatattta cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa
    67141 tgaattatca tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca
    67201 gagtattgag ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttatgacga
    67261 tttggagttg tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga
    67321 gagcaatcca gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga
    67381 aggaaagtcg acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac
    67441 catgattgct atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc
    67501 tggtggtggg tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga
    67561 tatgcatgct attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca
    67621 ccaagggaat gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt
    67681 gaacgaccgt gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc
    67741 acgtgaggat ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc
    67801 aacggacatc gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga
    67861 ccgtacgcct gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa
    67921 ggatgctatt aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg
    67981 tggtccattt gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct
    68041 tcacttggct gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa
    68101 attccttgat atcaagacac caaacttgcc aacatctcca gatgcagttg tcattgtcgc
    68161 aacccttcgt gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa
    68221 tgtagaggca gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa
    68281 gttcggtatt ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat
    68341 tgcagtctta aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg
    68401 ggctgatgga gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga
    68461 aaatccagct aactataaac gtttgtacga taatgccctt tctgtccaag aaaagattga
    68521 aaaaattgtc actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac
    68581 acaaattgct caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac
    68641 tcaatacagt ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac
    68701 cattcgtgaa ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt
    68761 tatgaccatg ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga
    68821 tggaactgta ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata
    68881 atatccaagc tcattttttc tcagactgca agcagttcat caataagatt tatactcttc
    68941 gaaaatctct tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactc
//
LOCUS       DAVBED010000005        66960 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBED010000005 DAVBED010000000
VERSION     DAVBED010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.005"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQ547_000308"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQ547_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ547_000309"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ547_000309"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2542229.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2147..2428)
                     /locus_tag="VQ547_000310"
     CDS             complement(2147..2428)
                     /locus_tag="VQ547_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2542230.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2599..2819
                     /locus_tag="VQ547_000311"
                     /pseudo
     CDS             2599..2819
                     /locus_tag="VQ547_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2936..3283)
                     /locus_tag="VQ547_000312"
     CDS             complement(2936..3283)
                     /locus_tag="VQ547_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2542231.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(3394..5169)
                     /gene="spxB"
                     /locus_tag="VQ547_000313"
     CDS             complement(3394..5169)
                     /gene="spxB"
                     /locus_tag="VQ547_000313"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2542232.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(5376..7619)
                     /locus_tag="VQ547_000314"
     CDS             complement(5376..7619)
                     /locus_tag="VQ547_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2542233.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(7629..8000)
                     /locus_tag="VQ547_000315"
     CDS             complement(7629..8000)
                     /locus_tag="VQ547_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2542234.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(8011..8406)
                     /locus_tag="VQ547_000316"
     CDS             complement(8011..8406)
                     /locus_tag="VQ547_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2542235.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      8590..8688
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8772..9563
                     /gene="thiD"
                     /locus_tag="VQ547_000317"
     CDS             8772..9563
                     /gene="thiD"
                     /locus_tag="VQ547_000317"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2542236.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(9772..10404)
                     /locus_tag="VQ547_000318"
     CDS             complement(9772..10404)
                     /locus_tag="VQ547_000318"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2542237.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(10397..11200)
                     /locus_tag="VQ547_000319"
     CDS             complement(10397..11200)
                     /locus_tag="VQ547_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2542238.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(11200..11724)
                     /gene="thiW"
                     /locus_tag="VQ547_000320"
     CDS             complement(11200..11724)
                     /gene="thiW"
                     /locus_tag="VQ547_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2542239.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(11729..12421)
                     /gene="tenA"
                     /locus_tag="VQ547_000321"
     CDS             complement(11729..12421)
                     /gene="tenA"
                     /locus_tag="VQ547_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2542240.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(12432..13082)
                     /locus_tag="VQ547_000322"
     CDS             complement(12432..13082)
                     /locus_tag="VQ547_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2542241.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(13084..14469)
                     /locus_tag="VQ547_000323"
     CDS             complement(13084..14469)
                     /locus_tag="VQ547_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542242.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(14470..15030)
                     /locus_tag="VQ547_000324"
     CDS             complement(14470..15030)
                     /locus_tag="VQ547_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2542243.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(15292..15380)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15589..16218)
                     /locus_tag="VQ547_000325"
     CDS             complement(15589..16218)
                     /locus_tag="VQ547_000325"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2542244.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(16220..17002)
                     /gene="thiM"
                     /locus_tag="VQ547_000326"
     CDS             complement(16220..17002)
                     /gene="thiM"
                     /locus_tag="VQ547_000326"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2542245.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(17245..17913)
                     /locus_tag="VQ547_000327"
     CDS             complement(17245..17913)
                     /locus_tag="VQ547_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2542246.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(18128..18216)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18470..19606)
                     /gene="lctO"
                     /locus_tag="VQ547_000328"
     CDS             complement(18470..19606)
                     /gene="lctO"
                     /locus_tag="VQ547_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2542247.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(20231..21721)
                     /gene="lysS"
                     /locus_tag="VQ547_000329"
     CDS             complement(20231..21721)
                     /gene="lysS"
                     /locus_tag="VQ547_000329"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2542248.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(21849..21995)
                     /locus_tag="VQ547_000330"
     CDS             complement(21849..21995)
                     /locus_tag="VQ547_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2542249.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            22221..22889
                     /locus_tag="VQ547_000331"
     CDS             22221..22889
                     /locus_tag="VQ547_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2542250.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            22849..23526
                     /locus_tag="VQ547_000332"
     CDS             22849..23526
                     /locus_tag="VQ547_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2542251.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            23527..24284
                     /locus_tag="VQ547_000333"
                     /pseudo
     CDS             23527..24284
                     /locus_tag="VQ547_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            24296..25157
                     /locus_tag="VQ547_000334"
                     /pseudo
     CDS             24296..25157
                     /locus_tag="VQ547_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(25237..25884)
                     /locus_tag="VQ547_000335"
     CDS             complement(25237..25884)
                     /locus_tag="VQ547_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542252.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(25881..26579)
                     /locus_tag="VQ547_000336"
     CDS             complement(25881..26579)
                     /locus_tag="VQ547_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542253.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(26589..27341)
                     /locus_tag="VQ547_000337"
     CDS             complement(26589..27341)
                     /locus_tag="VQ547_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542254.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(27341..28105)
                     /locus_tag="VQ547_000338"
     CDS             complement(27341..28105)
                     /locus_tag="VQ547_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542255.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(28201..28604)
                     /locus_tag="VQ547_000339"
                     /pseudo
     CDS             complement(28201..28604)
                     /locus_tag="VQ547_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28784..29416)
                     /locus_tag="VQ547_000340"
     CDS             complement(28784..29416)
                     /locus_tag="VQ547_000340"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2542256.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(29450..30151)
                     /gene="pyrF"
                     /locus_tag="VQ547_000341"
     CDS             complement(29450..30151)
                     /gene="pyrF"
                     /locus_tag="VQ547_000341"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2542257.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            30472..30564
                     /locus_tag="VQ547_000342"
                     /pseudo
     CDS             30472..30564
                     /locus_tag="VQ547_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(30886..31599)
                     /locus_tag="VQ547_000343"
     CDS             complement(30886..31599)
                     /locus_tag="VQ547_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542258.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(31592..32287)
                     /locus_tag="VQ547_000344"
     CDS             complement(31592..32287)
                     /locus_tag="VQ547_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542259.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(32627..33959)
                     /locus_tag="VQ547_000345"
                     /pseudo
     CDS             complement(32627..33959)
                     /locus_tag="VQ547_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(33943..34741)
                     /locus_tag="VQ547_000346"
                     /pseudo
     CDS             complement(33943..34741)
                     /locus_tag="VQ547_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(35531..36730)
                     /gene="divIB"
                     /locus_tag="VQ547_000347"
     CDS             complement(35531..36730)
                     /gene="divIB"
                     /locus_tag="VQ547_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2542260.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(36740..37798)
                     /locus_tag="VQ547_000348"
     CDS             complement(36740..37798)
                     /locus_tag="VQ547_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2542261.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(37800..39152)
                     /locus_tag="VQ547_000349"
     CDS             complement(37800..39152)
                     /locus_tag="VQ547_000349"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2542262.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(39256..39897)
                     /locus_tag="VQ547_000350"
     CDS             complement(39256..39897)
                     /locus_tag="VQ547_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542263.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(39899..41920)
                     /locus_tag="VQ547_000351"
     CDS             complement(39899..41920)
                     /locus_tag="VQ547_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2542264.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(41991..42290)
                     /locus_tag="VQ547_000352"
     CDS             complement(41991..42290)
                     /locus_tag="VQ547_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2542265.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(42656..42910)
                     /locus_tag="VQ547_000353"
     CDS             complement(42656..42910)
                     /locus_tag="VQ547_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2542266.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(42930..44771)
                     /gene="typA"
                     /locus_tag="VQ547_000354"
     CDS             complement(42930..44771)
                     /gene="typA"
                     /locus_tag="VQ547_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2542267.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            44933..45658
                     /locus_tag="VQ547_000355"
     CDS             44933..45658
                     /locus_tag="VQ547_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2542268.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(45698..45925)
                     /locus_tag="VQ547_000356"
     CDS             complement(45698..45925)
                     /locus_tag="VQ547_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542269.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(46014..46394)
                     /locus_tag="VQ547_000357"
     CDS             complement(46014..46394)
                     /locus_tag="VQ547_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2542270.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(46394..46663)
                     /locus_tag="VQ547_000358"
     CDS             complement(46394..46663)
                     /locus_tag="VQ547_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2542271.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            46727..47635
                     /locus_tag="VQ547_000359"
     CDS             46727..47635
                     /locus_tag="VQ547_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2542272.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(47689..48444)
                     /locus_tag="VQ547_000360"
     CDS             complement(47689..48444)
                     /locus_tag="VQ547_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2542273.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(48465..49394)
                     /locus_tag="VQ547_000361"
     CDS             complement(48465..49394)
                     /locus_tag="VQ547_000361"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2542274.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(49409..50032)
                     /locus_tag="VQ547_000362"
     CDS             complement(49409..50032)
                     /locus_tag="VQ547_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2542275.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(50025..51263)
                     /gene="hflX"
                     /locus_tag="VQ547_000363"
     CDS             complement(50025..51263)
                     /gene="hflX"
                     /locus_tag="VQ547_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2542276.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(51256..52140)
                     /gene="miaA"
                     /locus_tag="VQ547_000364"
     CDS             complement(51256..52140)
                     /gene="miaA"
                     /locus_tag="VQ547_000364"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2542277.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            52261..52431
                     /locus_tag="VQ547_000365"
     CDS             52261..52431
                     /locus_tag="VQ547_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2542278.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(52479..53318)
                     /locus_tag="VQ547_000366"
     CDS             complement(52479..53318)
                     /locus_tag="VQ547_000366"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2542279.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(53415..54374)
                     /locus_tag="VQ547_000367"
     CDS             complement(53415..54374)
                     /locus_tag="VQ547_000367"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2542280.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(54501..55499)
                     /locus_tag="VQ547_000368"
     CDS             complement(54501..55499)
                     /locus_tag="VQ547_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2542281.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(55549..56166)
                     /locus_tag="VQ547_000369"
     CDS             complement(55549..56166)
                     /locus_tag="VQ547_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2542282.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(56167..57888)
                     /gene="pabB"
                     /locus_tag="VQ547_000370"
     CDS             complement(56167..57888)
                     /gene="pabB"
                     /locus_tag="VQ547_000370"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2542283.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(57957..63644)
                     /locus_tag="VQ547_000371"
     CDS             complement(57957..63644)
                     /locus_tag="VQ547_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2542284.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(63666..64229)
                     /locus_tag="VQ547_000372"
     CDS             complement(63666..64229)
                     /locus_tag="VQ547_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2542285.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(64345..66036)
                     /locus_tag="VQ547_000373"
     CDS             complement(64345..66036)
                     /locus_tag="VQ547_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2542286.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(66033..66770)
                     /locus_tag="VQ547_000374"
     CDS             complement(66033..66770)
                     /locus_tag="VQ547_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542287.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        20079 a        14556 c        11839 g        20486 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
     2161 taaatgacat gtaccaatag aaggacttct tcttgctacg tttgagagtc ccatttccta
     2221 cattatctcg atctacatag ataaagccat agcgcttatt catttcccct gtgccagctg
     2281 aaaccgaatc gatacagccc catgtcgtat aaccaagcaa gtcaaccccg tctttgtaaa
     2341 tggcatctcg catggccttg atgtgggcct ctaagtaagt aatccgatag tcatctgcta
     2401 cataaccatt ctcatccggt gtatccatag caccgagtcc attttctacg ataatactat
     2461 actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa gaaatccaaa
     2521 ccatcaaaac actttttaaa gactctcgta cagctaaata tcataaatgc cttcaaatca
     2581 ttctatttcg tctgatgggc aaatcttata aagactccga ctaatattgg ttttgcattt
     2641 attcctccat acacaccaga gatgaaccca tcgaacaagt gtggaaagag attcataaac
     2701 gtggatttaa gaataaagcc tttcgaactt tggaagatgt catacaagga ctggagaagg
     2761 aggtgataaa gtccatcgtt aatcggagat ggaatagaat gctttttgaa agcagatgag
     2821 tattatatgc aatttcttta tataaaaaga ccggattgct ccgatctttc aatagttcat
     2881 attctcaatt tctattttaa aaatagctaa ggttaacgtc aaatgactac gcgacctatt
     2941 tcatacgata aaaatcaagc actagaccag caggtccttg aactaataag gactctgttc
     3001 cccaatcggt tacagttggt ccgtgtaaaa cctttatacc aagctcattc aaccgtttgt
     3061 agttctggtc tacatcctca acctcgatat gaataatgat tcctgactga aagttttcca
     3121 aaggaaccaa atgattttgt gacaacataa ggcagtgact accaatcgta aactgagcaa
     3181 aaccatcatc agcataatct gcctttttat ccaaaatatg ctccaagtca gcacagactt
     3241 ggggaacatt tgaaacgata atatctaatt gatttaaatt catttactct cctccataaa
     3301 aagaccgaat tgctccgatc ttttaaagtt ctgctctatg aaaatcaaag aataaagtct
     3361 acaagtttca tatttgattt tcggcgagag gaattattta attgcgcgtg attgcaatcc
     3421 ttcttcttcc aagaagagac ggaatggtac gagttcttct gcttcgtatt tttccttgaa
     3481 ggctttgata gcttcttctg agtgaagttt tggatccaat tcaagtactt ctactggaag
     3541 tggacggtgt tgagtgatgc gagcatcgat gacaacagtt ttaccttctt tgttcaattt
     3601 aacagcttct gcaacaactg catcgatgtc ttcgatacgg tcaactgtga atccaacagc
     3661 tccttgagct tccgcaattt tagcgtagtc agcgtttgtg aagtctacac caaacaagtg
     3721 tttgtttgta tcttcgtatt tgttcttgat gaagccgtac tcagcatttg agaagacaag
     3781 gttgataact ggaaggtcgt attgaacgtt tgtgataacg tctgggtagc acatgttgaa
     3841 tgctccatca cccatgatgt tccatacttg gcgatctgga ttgtctttct tagcagcgat
     3901 accaccagga agggcaatac ccattgtcgc aaagagcgga gatgtacgcc acatattctt
     3961 aggtgtcatg tgaaggtgac gagtagatgt ttgagtagtg ttacctacgt cgattgagta
     4021 gatagcgtct tgatcagcat gtttgttgat tgcattgtaa acttgataca attgcaattc
     4081 accctcagtt ttaccttcga gtttgttcat gtaatcacgc cagttttggt tgttcttaac
     4141 gtttgcacgc caccatggag ttgattcaac tgggtttact ttgtcaagga tagctttagc
     4201 tgcttgacca gcatcaccaa ggattgaagc gtcaagggca tgacgtttac caagtttgta
     4261 agggtcgata tcgacttgga tgaatttttc agtgttcttg aatgcttcgt aaacttcagc
     4321 aaatgggaag tttgaaccaa ggaaaagaac tgtgtctgct tcaaagacca cttcgttggc
     4381 tggtttccaa ccaacacggt aagcagaacc tgtcaaacct tcatagttcc attcgaaagc
     4441 ttcaaagttt ttaccagttg tgatgattgg tgctttgatt ttacgtgaca attcagtaat
     4501 cacttcacca gctttaacac caccaaatcc agcatagata actgggcgtt cagcattgtt
     4561 caagatttca acagctttgt cgatttcaac ttcgttcaaa gcaggagcga tgaatgagcg
     4621 ttcgtatgaa cctgaaccgt agtatgagtt ttcgtcgatt tcttggaaac cgaagtttac
     4681 tggaatttca acaacagctg gacctttttt agaaattgca gcacggcagg cttcgtcaat
     4741 tacttttggc aattgctcag cgtaagctac acgtttgttg taaacagcga taccgttgta
     4801 cattgggttt tggttaagct cttggaaagc atccatgttc aattcgttaa ctggacgtga
     4861 tccaaggatc gctaggaatg gagtgttatc catagctgca tcgtaaacac cgttaatcaa
     4921 gtgagtcgca cctggaccac ctgaaccaac tgcaaccccg attgagccgc cgaatttagc
     4981 ttgcataacc gctgcaagag cacctgtctc ttcgtggcga acttgtaaga agcggatatc
     5041 tttgtcttca gccaaagcgt ccatcaatga gctgagtgtt cctgatggga taccgtagat
     5101 tgtatctacg ccccatgttt tcaatacgtt aagcattgct gcagatgcag taattttccc
     5161 ttgagtcata atgataactc tccttcaatt tttttagatt tggagaatac gattacatag
     5221 aattggaaac gttctccaaa tttttactat tccactgtat catatttatg ctgacttttc
     5281 taaaaatctg ctcaaaactc tctattctct attctaatac agttttgaaa gttctgtcat
     5341 ttctgtttta taacaaagaa atctagtcat tacttttagt ctattttact aaaatttaac
     5401 agaagggaac tggtcagaac agatacagaa ctaaaggcca tggctagacc tgccaattct
     5461 gggttgagag ccagtccaac acctgaaaag actcctgctg caatcggaat tccgacaaca
     5521 ttgtagataa aagcccagaa aagattgagt agaattcgat gaaaggtttt cttactcata
     5581 tcaaaggcac gaaccactcc taaaagatta ttggttgtca acaccaaatc tgctgactcg
     5641 atggcgatat ctgttccagc tcccatagca atccccacat ctgctacact aagggcagga
     5701 gcgtcattga taccgtcccc aacaaaggct actttccctg actgttgcag tttatggatt
     5761 tcatgggctt tttcttctgg caagacgcct gcaatgacct cttcaattcc gatttgatct
     5821 gcaatagcac gcgccacacc agcattgtct cctgtcagca tgactgttcg gagaccacgt
     5881 ttttttagct gactgatggc tagcttagca ttttccttag gaatatcttg caaagcaagc
     5941 aagcctttga tttcattgtc aacagctaag aacacaactg tcttagcttc tttttctagt
     6001 tcttctagtt tatcttgata agtattagaa atatccatac catccagcat tttagcattt
     6061 ccaagtaaaa cttgttttcc attgattcgc cctgaaacac ctttcccgtg caaggactga
     6121 aaattttcaa cagtttgaaa ctcaagtcca gcttcactcg ctcgcttaac gatagcctca
     6181 gccagtgggt gttgagaagc atcttccaag gaggctgcca atccaaacac ttctacttcg
     6241 tcgccgatga tatctgttac cacaggtttc ccttccgtca aagtcccggt cttatcaaag
     6301 acaagagttt gaactttctg gatttcctgt aagacagttc catttttgag gagaaccccc
     6361 atcttggcac tacgtcctgt ccccaccata agggctgtcg gtgttgcaag tcccaaggca
     6421 caaggacagg cgataatcaa aaccgccact ccgtagagaa gagaggacac aaagctagct
     6481 ccaagcacga ccacactatc cctgagcaag acgaaccaaa cccaaaaggt catgattcct
     6541 aaaatgacaa ctactgggac aaaaatccct gaaatcttat ccgtcaagtc ctgaatcggc
     6601 gcacgacttg tctgagcttt cttcacaaaa tccacaatct gagccaaaac agtctctgag
     6661 ccaacttttt ctgctctaaa gacaagcgtt ccactatgat tgatggttga gccaatgaca
     6721 gtatctccaa ctgtcttgtc cacaggcaga ctctcacctg tcaccatgga ttcgtcaata
     6781 ctagagacac cttctactac gacaccatca acagcaatct tttcaccggg acgcactcga
     6841 atcaggtcgc ctaccttgac ttgttccaaa ggaacttgga cataactatc atcactcaag
     6901 acttctgcgg ttttagcttg caagtccagt aatttctcca cagcttggga cgtatttttt
     6961 ctcatttttt cctcaaaaac tgctcccaaa agaacgaaaa agaggataaa tccagcactt
     7021 tcgaagtaaa cagggagacc agcaaagaga gcaactaggc tatagaaata agccactaga
     7081 gttcccagcg caaccaaggt atccatgttg gcattgtgct ttttaaaact ggcccaagca
     7141 ctctggatat atggcttacc tgcaactaac ataataggcg ttgttgctag aaaggttccc
     7201 caatgcatga cttgatgact aatgctacct gtcaacatcc caatcatgag aatcacaaga
     7261 ggcacagtaa agatactagt aatccaaaaa cgttgcagga gagatagaga ttttcgagtc
     7321 ttctcaacga ctatatagct tcccttttgc atcttcatgc cacaagaaaa ttcatgtcgc
     7381 cctaattctt gaggtgtaaa acgaatgact ttctcctcat ctacgccgat tggttccaag
     7441 ataccttctt cttcaaacag aatttcctta taacagtttg aaggagtagc acgatgaaag
     7501 gtaatctcag ctggaattcc cttttgaagc tggatatggg ctggatgata gcctttttca
     7561 gctcggatac ggattttttg aatgccattt tctaagcttg ctttcacaat ttctgtcata
     7621 gtctccacct actctacaat catcttgccg tgcatcatgt tcataccaca agcaaagcca
     7681 aactctccaa cctgctcagg cgtgatttcc actacatact cttcccccat tggcaggttc
     7741 gcatgtacac caaaatctgg aaaaacaatt tgatccagac atggtgaagg atccttgcgg
     7801 tcaaagacaa tgcgtgctgg cactgatttc ttgaggacaa tcaactcagg agtatagcct
     7861 cccatgactt ccactcgaat ctcttggtat ccgttttttt gctgggcttt ttgtccagat
     7921 ttttcaggct ttttgaaaaa ccaaaacaag ataaacgcga taagggcaat acaaataatg
     7981 gttacaatac tatttaacat gacgtctcct ttacatacaa ttacatctta cttctgttac
     8041 agcacttgat ttcttctctg aaatcacagc ttccaagtct tccaagtcag tctgagtaaa
     8101 ttcacattct acaatcaagt cagccaacaa attcctaatc ctacgggaac aaaccttgtc
     8161 tttgatatct tggacaagta aatcccgact ttggtctaga gttaaaaggg ctgaataaac
     8221 aaaggacttg ccttcttttt tccgagtcag acactctttc tcaaccaaac gagccaaaag
     8281 agtttgaatg gtcgacttgg accagtcgaa ccgctctgcc aaaaccctaa tcaaatctgt
     8341 actggtctgc tccccctgca tccaaataat cttcatgacc tgccattctg catctgaaat
     8401 ctgcattacc atacctccaa aatctacatt tgtcaattac actcatcagt atactcttaa
     8461 aatctacatt tgtcaattat agaaataata ttttcttcga aaaatagaat tttaatcatt
     8521 tgaaaaacga tttgcagtca aatattacta tataaacaat aaaaatatgc tatactaaag
     8581 aaaaaagaaa acaaccacta ggggtgcgta aagctgagat taacgactgt tagatccctc
     8641 tgactcaatc taggtaatgc tagctgatgg aagtggaaat gataatgggg actagcagtc
     8701 ttctattgcc tttctaaaac agactagctt gttcttaaga atacaaactt cagttggttg
     8761 ggaggtttta gatgacttat ttacccgttg ctttgaccat tgcagggact gaccctagtg
     8821 gtggtgctgg cattatggca gatttaaagt cattccaagc gagagatgtc tatggaatgg
     8881 ctgttgtaac cagtcttgtc gctcaaaata ccagaggtgt tcagctaatc gagcacgttt
     8941 ctcctcaaat gttgaaagcc caattggaga gtgtcttttc tgatattcca cctcaggctg
     9001 taaaaactgg aatgttggct actactgaaa tcatggaaat catccaaccc tatcttaaaa
     9061 aactggattg tccctatgtc cttgatcctg ttatggttgc tacaagtgga gatgccttga
     9121 ttgactcaag tgctagagac tatctcaaaa caaacttact acctctagca actattatta
     9181 cgccaaatct tcctgaagca gaagagattg ttggtttttc aatccatgac cccgaaggca
     9241 tgcagcgtgc tggtcgcctg attttaaaag aatttggtcc tcagtctgtg gttatcaaag
     9301 gcggacatct caaaggtggt gctaaagatt tcctctttac caagaatgaa caatttgtct
     9361 gggaaagccc acgaattcaa acctgtcaca cccatggtac tggatgtacc tttgctgcag
     9421 tgattactgc tgaactagcc aagggcaaga gtctttacca ggcagttgat aaggccaagg
     9481 cctttatcac aaaagctatt caagatgccc ctcaactcgg tcatggttct ggtccagtca
     9541 accatacaac ttttaaagat taagaaaaaa actctctagt tcccacttta agggaattag
     9601 agagttttta tactcttcga aaatctcttc aaattacgtc agcttccatc tgcaacctca
     9661 aaacactgtt ttgagctgac ttcgtcagtc ttatctaaaa cctcaaggca gtactttgag
     9721 caacctgcga ctagctttct agtttactct ttgattttca ttgagtatta attaggaaag
     9781 aatgtcatgc aactttgtta aaaaggcttg cgtttttgcc tcaatatctt ctgcttgcat
     9841 caaatcacgt acaacagcta caccagctat gccagtgccc ataagctgat caatattctc
     9901 cgaagtcaag cctccaatag caactactgg aatggcaacc gtttggcaaa ttgttttcaa
     9961 ggtcgatatc agagtaatgg gcgcattttc cttggtggtg gttgggaaaa tggctcctgt
    10021 acccaagtaa tctgcacctg atttctccgc ttccagagct cttttaaccg ttttagcggt
    10081 gacaccgagg attttttcag gacccaagac tttgcgagct accgaaactg gtaattcatc
    10141 atctccgata tgcagacctg ctgcatcaac cgcaagacaa acatccaacc gatcatcgat
    10201 tatcaagggg acctgatagg catctgttat ttccttgact tgttttgcca gttgataata
    10261 ttgattggtt gtgagatttt tttctcgcaa ttggactatg gtaacccctg aacggcaggc
    10321 cgtctcaact tttgcaagaa agctttccac ggaatcttga tagcgattgg ttaccagata
    10381 tagtctaagt gcttctctat tcataaacct ctcctttgat ggtatctagc caattttcat
    10441 ctcttcttag gagcgaaagc tgattgagta cttggtaacg aaattcttcc aatcccattc
    10501 cttgaacaac tattttctca gcagcgatat tgagataaga gactgctaag caagaagctt
    10561 caaaaccagt ctttccttgg ctgagaaaaa cggctgttaa ggctccaacc aagtctcctg
    10621 tccctgttat ccagtctaat tcagtacagc cattctccag tacagcaact tgattctccg
    10681 aaacaataag gtccttgggg ccagtaacta agaaagacat accaggatag gtctgacacc
    10741 agtctttcaa gacttgaagc aaatcctccg tttcttgatc tttagcactc gcatcgaccc
    10801 caacgccgtg gtgctttaat ccaacaagac ttcgaatttc tgacatgttt cctttaagga
    10861 ccgtaggtct atagtctaaa aggtctttaa ctaagctctt acgaatggat gaagtcgtta
    10921 cgccaaccgc atctactacc atcgggagag aagattggtt tgcatacgaa gctgccatgc
    10981 ggattgcttt ttccttctca gctgacaaat gccccaaatt gatgaagaga gcctgacttt
    11041 gcttagtaaa atcaagaact tcacggggat catctgccat gacaggtttg catcccagag
    11101 ccaaaatccc atttgccagc atctcacaag aaatctcatt ggtcatacag tgaatgaggg
    11161 aactagagcc tataggaaaa ggatttgtca atgcctgcat cagtctatcc tttcagcaaa
    11221 gaaatatcct tgcacttttt taaagaattc ctgcttgatt aaaaatctaa atgcaataaa
    11281 ggaaatcgct gtaccaatca aggttgctcc gaaaaatcga ggagtgtaga taaaccaact
    11341 aagcttagca gccgatcctg taaagagcac cataacagga taggaaacaa tagaaccaat
    11401 aatacctgtt cccacaattt ctcccaaggc agaaaagtaa aattttcgac cgtacttata
    11461 aaagagacct gctagaaggg ctccaaaagt cgctcctgtg agagctaaag gcggaatccc
    11521 ttgagtcgtc atacggataa aggctgtcac tgtagccata gccaaggcat aaacaggtcc
    11581 catcatgatt cccgctagaa tattgactac actggacatc ggtgccattc cctcaatccg
    11641 aaagataggt gtaaggacta catcaagggc aatcatcata gataaaatgg tcaatttgtg
    11701 aacttgtagt tggtgctttc tcatgtttct attcttctcc tttttctaaa gactgtaaat
    11761 cgctcttcca tgtctggtgt tggtaagcca tctcccaaaa cttggcttcc atatgaacac
    11821 tgatgtggaa ggcatctagc attttttgct tatctgtctc atcactttct cgataaagct
    11881 gattgaccag tgctccctcc tctctgatct gttgctctaa ctcatccgta atataagttt
    11941 caatccattg ttgatagaga ggatttggtg atggtttaag attaagtgat ttgcctatat
    12001 catggtataa ccaaggacaa ggaagcaagc ttgcaaaagc tatggctaag ttcggttctg
    12061 caaattgcct ataaatatga gaaatgtaat gataacaggt tggagcgatt ggatgttgct
    12121 ccatttcctg gtcgttgatt tccaattcct tgaaaaattg ttggcgaata aataactcac
    12181 cctccactaa accctgagca ttttgtttca agagtctttt catctcttgg tttgaagtct
    12241 tatcagccaa aagatgatag atttctgaga aagccttcag atagtaggca tcctgaatca
    12301 ggtaatagcg gaaaatggca ggttctaaat tcccctcttg taattgtaaa ataaagggat
    12361 gatgaaagga agcctgccaa gctttcttgg ataattccat cgcaatatct gtaaattcca
    12421 taataactcc tttataaaaa tagactggtt tgaagcaata aaaagaaaag caggtagatt
    12481 aattttgttt ttttaggaat ataaaaagtc cgatagctat tcttcaactg tgcatgttcg
    12541 tcatatccgt aagcagatag agctctcagg taaagatggc gccacctaaa gactgtcatc
    12601 agaaccttac tgtaaatcaa gggcgaccaa aaatgtagtt tttgaccacg taataggcaa
    12661 gcttctttga gggacttgat ttcttgctga atgagaggaa aagaattgaa taccacaatc
    12721 aaggcatagg accaagagcg tgatagcccc ttttgagcca agtacaagag aagctctttt
    12781 agtgaaatag aggaaacaaa gacaaggccg atacaaactg tcacaaaggc cctcgttcca
    12841 agcatgactg cctgtgaagc atctccgtgt aactgaactg cccagtagtt ggcaaaagat
    12901 gggaaaatgg caagtatgat catccaagct aacattttaa atcgacggta atagagcata
    12961 aagagaatac aaaatgcgac taccgaaaga ttcagagcaa tcgaaggaat gaaagatgtt
    13021 tccaaggata aaatcagcaa gaagagactg ataatcggtg tctgggttgc tactttgacc
    13081 atactatctc acctcccctt gggtattgct actctgagat gtaagtggtt tggtaatggt
    13141 cacttctttc acatgccgaa gaccctgact agtcatctca atccaataat caaccacaga
    13201 aatcaaaggg tctaaacgat gactaatgag cagaaaactt cttccttgat tcctctcctc
    13261 cacaatccac ttgcaaaaat aatggcaggc tctatcatcc aaacctgcaa aaggttcatc
    13321 tagcaagatc acggaagcct tactggtcaa gatggtcagg agctgaagaa ttttttgctg
    13381 accaccactt aattgatagg gactcttatc gactgcctgc tccaaatcaa aatatcgtaa
    13441 agcttgaaaa atccgctgat ttctttcaga atcaggtcca tctaattgaa gctcctctcg
    13501 cagactgact cggataaact gcttctcagc ttcctgaaca acaccagtca gatcacgata
    13561 caaactcttt ttctttttca ggaccgaacc cttccaagta atgctcccct tatacttttg
    13621 aaattgaaga atagaccgaa agagggttga tttcccgaca ccattgtcac ccaggataca
    13681 ggaaatccct tgatagaatg tgaaatcagc aattgaaaag agggggcgat taccaagctc
    13741 accagtcaca cggttcatat ggaatagttc cgggctagaa gcaacttcct ttgaagcaac
    13801 ctgtgtcatc tcataggaag ggatttgaaa cacttccctt agttttccgt ctcttagctc
    13861 caccatatgg tcgatatagg ctttatagtc agataaatca tggtcgcaca aaataactgt
    13921 cttcccatca tagaccaact cttttagaat ctccaatatc tcgattctgc tcttgcggtc
    13981 aatggaagcg aagggctcat ccaagagata gaccctagga ttcatggcaa agaggacagc
    14041 cagcgctgct ttttgctttt ccccacctga taagtgatgg atgagacggt gcaagatgtc
    14101 cttgcaacga cattgctgga caacctctgc tattttagaa tcaatttcct gaaggtgata
    14161 gccgatattt tccatggtaa aaaccaactc ctcaaacaag ctctccatgg taaattgatg
    14221 attaggattt tgcaagagaa taccaaccgt ctggacacgt tcgacgatag aaagctgact
    14281 gacctcgctc ccatctatca ggacttgacc gctataggga agagaactaa cttgggcaat
    14341 catttgaaag aggctggatt ttccagaccc actactccca actaacaagg taaaggcttg
    14401 cgcatgaaaa gtaaaatcaa acggctcaga gaagattggg gactgaatcg ctcgtagttc
    14461 cagacccatc tatgcttttc ctccagttgc aaactgatga tagagtttga caatggcacg
    14521 aaccaagatg gtacagaaga aataaacaga aataaaacgt accacaagca aggaaaggac
    14581 aaacggaagg gaaaaggcgt agtaacctaa cttaatgtat tcatagacaa agctaacaag
    14641 cgtaatccca atactattag cagttagaga gagccaactt tcatagcgat tcttagttac
    14701 gataaaacca aattcacttc ccaaaccttg aacaaagcca gacaaaagag ctcctagacc
    14761 aaattggcta ccataaagga cttcagcaag cgcagctagc acttctccaa tcgttgcact
    14821 tccgactctc ggaacaaaga tggcagcaat gggcgcagcc atacaccaga gaccgaagag
    14881 gatttcattg gcaaaggcct gcaaaccaag aggtgttaag agtagactga gaatattata
    14941 cacatatcct gaaccaacga aaaccccacc aaaaaagata gacaagaaag caagcaagat
    15001 aacatctttt aactgccatt ttttcaacat aaaaaactcc tttttttaaa gaaaagtggg
    15061 gcactcaaga agaccgacct aaatactttg tatagcagac tgaatttaga acagtacaca
    15121 agaacactaa aatatttcta gaaattaatt tgaattttct aattgatttg ttcgcatctt
    15181 atttcaatct actatatcat cttcatccag tttcgtaaaa gaaaaaactc taattacaga
    15241 tacaaattag agttcagctt acaagattag acagttcttt tcgacatacg aaaaaaacat
    15301 ttcacatttc ccttcgccag tcttaactgt atcaggttca atgggtatca tctcagccta
    15361 aagcacccca aatgtcttta ttatttaatt atgtgattat tataacacac attttatact
    15421 agttcaagaa attgaactgg aaatacagcc ttgcactcac aaagacagca gatctttctt
    15481 ttgcaaaaaa caaatgacct gtttgatgaa ttagccattc aagctgaatc tggacatagc
    15541 tttttaaaaa aggaaaatcc tacttactta gaatccaagg atagatatct attgttcact
    15601 catttcccga acagtttttt ctatattttt tgcatacgat attgccgaaa tgattgaaac
    15661 gccatccata ttggtcttta taatgtcttt aatatgtttc gtctgtatcc caccaattgc
    15721 aactaaaggc atttgtggca atagttttct catcaattca agaccttcat aacctatagt
    15781 accaccagca tcatcctttg actgggtacc aaatacaggc ccaacaccta cataatctac
    15841 atattcaact tttgattgtt gaaattcttc ttcgtttctt atagaaagac caattatttt
    15901 atctggcatc aattttctaa tttcatcaac accaatatca tcttgaccta catgtacgcc
    15961 atcggcgtca atttccattg ctaaatctat atcgtcatta acgataaatg gaacattgta
    16021 ttttttacaa agttctttaa tttggatagc tagctcaagt ttttctaagc cttctaaagc
    16081 accctcacct ttttctcgaa attgaaataa ggttatacca ccttttaagg cttcctcaac
    16141 gactgtatat agattttttc cttggcaagt agtcgttcca caaataaaat atagttttag
    16201 taattcttta tgaaacatct tacttcactc ttttgaattc ctttacatct tcatctgtaa
    16261 tctcgtataa ggcatttata aattcaactt taaatgtccc aggaagatgt ccatttggac
    16321 gtttttctgc catttctcca gcgatattgt aaaccaacat tgctgtttct aatgatttca
    16381 attcttgacc tttttctagt ccgataaagc ttgctactac agctcctaat aagcatcctg
    16441 tcccaatgac tttcggcatc atagcactac cattatgaat cattaccact tctccattaa
    16501 cagcaatggc atccacttca cctgttacta ctattggaat attgaacttc tcatttgctg
    16561 ctagagcaat ttcgtcaata ttatctacgc ccgcactatc tactccttta gatgccacat
    16621 ctattcctac taaagaggca atctcgccag catttcctct aatcgctgct agtttataat
    16681 tgttgattag atcatctgct actttttttc tatattctcc tgctccacag gctacaggat
    16741 ctaaaactgc tgggacatta tatttctctg caattttcag agcagcttgg tataatttcc
    16801 aattttcatc tgtcaatgtt cctatgttta ttaataaacc accagcatac tttaacaaat
    16861 cctctaaatc tgctggaaac tcactcatgg ctggtgaggc gcccagtgct actaatccat
    16921 ttgctgtgaa attttttact acatcattgg ttatacaaat gaccaatggt gctttttctt
    16981 ttaataattt taaacttgtc atattgaaat ccttcctttt cactttatac gatctactga
    17041 tttcgattta tttctatctt tcgttaagaa tttttttcat ttacattgaa tgatttatac
    17101 tcaatgaaaa tcaaagagca aactaggagg ctaaccgcag gttgctcaaa acactgtttt
    17161 gaggttgtgg atagaactga cgtggtttga agagattttc gaagagtctt acctcatcaa
    17221 atttgtaaat atcatgagcc ttctctagac atcgtaacca atatcaaaaa aagctaattc
    17281 taaagcgact gcttgattcc agcgttgctg aagttctgtc aaatcttctc gatttttatc
    17341 gacacgattg agttcgtcaa ccagaaattg aacccactct gcaaagaaag gacctctgtg
    17401 gagattgatc cattccgaat gaatatagac ttcaggtaaa gccaaatctt tagaacccca
    17461 gtctaaatag agaccttctg caatgaccag catgaccaaa agatgggcat agtctgatga
    17521 agccaccgcc gaatacatta gatcctgaaa ggcttttgtt acagggtgca aagtcacttc
    17581 tagatagtca ttctctgcta cttttaactc tttaaaagcc ttttggaaat aaccatcttc
    17641 atctgcttca agaaagccta gttgcttggc aaaacgaagc ttggattcaa gtttatctgc
    17701 gtgagctacg caggcaccca gcatggataa gaaggcatca aagaagtgat aatcttgaat
    17761 cagatagtcc tttaagacct tattctcaat tgtccccgca aaaagttcct taacaaaacg
    17821 atgattgatt gcagcctgcc aatccttctg actgcttttt aataattctc caacagtcaa
    17881 acctggctga aatgcatagt cttgtgtttc catatttact tctcctctct ttacttgtta
    17941 gtaattaata aaacaccaag aaatatcaag caaaatcgta attccacttg atccttttaa
    18001 agcacatcga gagcatttgc agagagctaa ctaaacaagc ctatccagtt tatataaaca
    18061 aaaaactcca attacaatca agaattagag ttgacttaca agattagatc gttcatttcg
    18121 ccatacgaaa aaacgtttca catttccctt cgccagtctt aactgtatca ggttcaatgg
    18181 gtattatctc agcctaaagc accccaaatg tctctattat ttaattactg aaccagtata
    18241 gcaaaaaatg aaagccctag caagatattt gaccgaaaaa tatctttata tataatatat
    18301 tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat ttgactgtcc
    18361 tgattgattt gtcctattct tatttcattt tactatagtt ttcgatagca atttattctt
    18421 ccaatacacg aagaaaaacc tccacattca gtggaggcaa tctgttttat caatacaatt
    18481 ttaagtcacg agggtcaact gggaaggttg ggttgtatgg attgtgacgg agcttaaagt
    18541 gtttgacatc ttcaatggtc tgagctccag acaattgcat aactgtcttc aattccgcat
    18601 tcaagtgttc aaagacttga cgcacaccga cactaccacc gagagccaag ccataaataa
    18661 cagggcgacc aatagctacc aagtctgctc ctgaagccaa ggctttaaag acgtgttgac
    18721 cacgacgaac accagagtca aagacaatcg gcacacgtct atcaactgct tctgccactt
    18781 cttgaagcga gtcaaaggca gctggtccac cgtcgatttg acgaccaccg tggttggtta
    18841 cccagatacc agaagctcct gcagcaagtg aacgttcaac gtcctcacgg cattgtggtc
    18901 ccttgacata cacaggaaga ccagagtatt cagcgataaa ttctacatcg cgtggagaca
    18961 agcgttgttt agctgatttg taaacaaagt ccattgattt accagcacct tctggcaggt
    19021 attcttcaac aatcggcatg ccaactggga agacaaaacc attacgctta tccacttcac
    19081 gattcccccc tacagtagca tctgccgtca agacaatcgc tttataacct tcagccttca
    19141 cacggtccat gatgtggcgg ttgataccgt catccttact aaagtaaaat tggaaccaat
    19201 ggggtgtccc ttgaagggct tcagaaatct ctggaaggtc aacagtagag taagagctgg
    19261 ttgtataaag agaaccaaac tcatgcacac cacgcgcagt cgccacttcc ccctgttcat
    19321 ttgccaattt atgagccgca acaggcgcca taatgattgg tgaagatagt ttttcacctg
    19381 caaattcaat ctctgtactt ggattttcaa catcgcaaag tgtatgagga acgatgagtt
    19441 tgtggttaaa ggcgcggata ttctctctta aagtgaaagt atcttccgcc ccactagcga
    19501 tatagccaaa tgctgcttta ggaataactt gttgcgccat tggctccaaa tcataggtat
    19561 tgatgaagtc tacatgacct tctgcattgc ttgttttgta tgacataaaa tgccctcctt
    19621 gattaagtaa gcgtttgctt tttactacac aactataata actctttttt caatcatttt
    19681 caagagtttt gcttaaaaac catcttattt tttcatacaa tatactagcc ctactttcct
    19741 taaactctaa actttagtct atattaagtg aatcgttgag attttttgct gccaggcatt
    19801 tgaactactt ttttatttgc ggattctatc tactaatact ataaaaaaac aagtgaataa
    19861 gacaccagaa catcctctaa taggacctat ggacttatat cagtcccata tatactgttt
    19921 aagcaagata ctatcctagt tgacgctaac ttcctatccc acttattaat tttttattta
    19981 tagtgaatct gaacaaatca attggggaat ccaagtcaat ttctagtact ttttgaacag
    20041 tttcagcgta ctatcgtaaa atgaaataaa acatgcacaa attgcttagg gaatttaaac
    20101 caatttctaa caatgtctta gaaatcaaag tgtactattt caacttcaat atactacact
    20161 tcattttctc cttaaattca gtctcttttt gaatcaaaaa atcccctggt aagagccaga
    20221 ggataagaat ttatttcatt gttgggaaga gcaatacatc acggatagtt gttgtatcag
    20281 tgaggagcat gcagagacgg tcgataccga ttcccaaacc acctgttggt ggcataccgt
    20341 attcaagagc ttcaatgtag tcatagtcga tgcctgtcgc ttcatcatca ccaagttctt
    20401 tggctttagc ttgggcttca aaacggctaa gttggtcgat tgggtcgttc aactcagtaa
    20461 aggcattacc gtactcctta gtcatgataa agagctcgaa acggtcagta aagcgttggt
    20521 cttcaggatt tttcttagcg agtggagata cagctactgg atgtccatag acaaaggttg
    20581 gttggattaa agtttcttca acaaactctt caaagaaggc attgatgatg tgaccaacct
    20641 cagtgtagtg tttctcaact ggaactttct tctcagcagc gatagtttta gcttcttcca
    20701 aagtcatgtc ttgccagaaa tcgacaccag taatttctct gatagcatcc accatatgaa
    20761 cacgcttaaa tggttcgtta atcttgattt cagtaccttg gtagttgact gggccatcac
    20821 ctttgactga tttagcagcg tgttggataa tgccttcagt caagtccatg atgtcttgga
    20881 agtctgcata agcttggtaa acttcgatag aagtgaactc agggttatga gtagcgtcca
    20941 ttccttcgtt acggaagata cggccaattt catagacacg ttccatacca cccacgataa
    21001 ggcgtttcaa gtgaagctca gtcgcgatac gaagcaccat gtcaatgttt tgggcattgt
    21061 ggtgggtgat aaatggacgg gcagcagcac caccggcttc attatgaaga acaggtgttt
    21121 ccacttcaag gaatcctttt tggtcaaggt aacgacggat ttcagagatg atttttgaac
    21181 gagtgacaaa gcgttcaaag ctttcacgat tagaaatcaa gtcaaggtaa cgtttacggt
    21241 aaattgtttc aacgtctgtc aaaccatgga atttctcagg aagaggacga agagccttag
    21301 acaagtgtgt gatgtgggtt gccttgatag agagttctcc catatccgta cgcatcactt
    21361 caccttcgac accaaggaag tcaccaaggt ctgctttttt gaagatttcg tagttttctt
    21421 caccgacagc atccttacga acgtagatct gaatctggcc ttcgcggtct tgaaggtggg
    21481 caaaaccaac ttttccttta ccacgtttgg ttatcaagcg tcctgcgata gtagctgttt
    21541 cgtttttatc gtgtaattgt tctttatcga ggttggcata tttatctttt aattcttgtg
    21601 aatttgcagt acgttcaaaa cgttttccga aaggatcgat tccttgttcg cggagcgcag
    21661 ccattttttc acggcgaacg atctgctggt catttagttc ttccatatgt tctgtagaca
    21721 tgggatcctc ctagttttac tcaaaattga atacgatgag tcattttttg cgatactccc
    21781 attttatcat aaataagcaa gaaattcacg gataatcttt aaaaactaaa aagaacctga
    21841 cgctaaaatc actggaaaga agtgaaagta tctcccgccc cactagcgat atagccaaat
    21901 gctgctttag gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaaatct
    21961 acatgacctt ctgcattgct tgttttgtat gacataaaat gtcctcctta ataagtaagc
    22021 gtttactttg tgtattacaa aaatatctta actctttttc aaaactttta aaatattttg
    22081 tttggaaatt tcagaaattt tatgtctatg ataaaaatcc ttataacggc aataaaaaat
    22141 agatattatc caaagaagat tttaagtgct acaataactg tattatttct agatgggagg
    22201 ttctattttt ggattgatcc attgttgaac aatatctacc actatatcaa aaggcattct
    22261 ttctgacctt gcatattgca gtttggggaa ttttgggatc ctttctgctc ggtttaatcg
    22321 ttagtatcat ccgacattat cgaatccttg ttttggcgca agtagcgaca gcctacattg
    22381 aattgtcacg taatacgccc cttttgattc aactcttctt tctctacttc ggtcttcccc
    22441 gaatcgggat tgtcctatct tcagaagtct gtgcaacgct tgggcttgtc tttttaggag
    22501 gctcctatat ggcagaatct ttccgaagtg ggctggaagc catcagtcaa acccagcagg
    22561 agattggcct cgctattggt ctgacacctc tacaggtctt ttactatgtg gttcttccgc
    22621 aagcaacagc ggtggcactc ccctccttta gtgccaatgt cattttcctt atcaaggaaa
    22681 cctctgtttt ctcagcagtg gctttggccg acctcatgta cgtcgccaag gatttgattg
    22741 gtctctacta tgagacagac attgcgctag ctatgttggt agttgcttat ctgatcatgc
    22801 tgctacccat ctcactggtc tttagctgga tagaaaggag gctccgccat gcaggattcg
    22861 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg attgggcgtt
    22921 acgattgaga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
    22981 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggacttt
    23041 acccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt agctcgaaac
    23101 tttaatatca atatctcagg tgagacttca gctattatcg tttttaccct ctggggagca
    23161 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
    23221 agtggacagg cactcggctt gactaatgtt caactttact accacatcat catcccacaa
    23281 gtcttaagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
    23341 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
    23401 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
    23461 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
    23521 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
    23581 cccatcctcc aaggactttc tctagaaatc aaaaaaggga agttgttgtc atcctagggc
    23641 catctggttg tgggaaaagt accctccttc gttgcctcaa cggcttagaa agtattcaag
    23701 gtggagatat tcttctggat ggtcagtcta tcgttgaaaa taaaaaagat tttcacctag
    23761 ttcgccaaaa gattggcatg gtctttcaaa gttatgaact ctttccccat ctggatgtct
    23821 tacaaaacct catcctaggc cctatcaaag ctcaaggaag ggacaagaaa gaagtaacgg
    23881 aagaagcttt gcaattacta gagcgtgtcg gtttgctgga taaacaacat agctttgccc
    23941 gtcaattatc tggtggacag aagcaacgtg ttgcaattgt ccgtgccctc ctaatgcatc
    24001 cagaaatcat cctttttgac gaggtgactg cttcgctgga tccagaaatg gtgcgtgagg
    24061 tgctggaact tatcaatgat ttggcccaag aaggccgtac catgatttta gtaacccacg
    24121 aaatgcagtt tgcccaagcc attgctgacc ggattatctt cctcgaccaa gggaaaatcg
    24181 ctgaagaagg aacagctcaa gccttcttta ccaatccgca aaccaaacga gcccaggaat
    24241 ttttaaacgt ctttgacttt agccaattcg gctcatatct ataaaggaga ttcttatgaa
    24301 actattcaaa ccactcttaa ctgttttagc acttgccttt gcccttatct ttatcactgc
    24361 ttgtagctca ggtggaaacg ctggttcatc ctctggaaaa acaactgcca aagctcgcac
    24421 tatcgatgaa atcaaaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg agataaaaaa
    24481 ccgtttggct acgttgacaa tgatggttct taccaaggct acgatattga actagggaac
    24541 caactagctc aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc tgccaaccgt
    24601 gcggaatact tgatttcaaa caaggtagat attactcttg ctaactttac agtaactgac
    24661 gaacgtaaga aacaagttga ttttgccctt ccatatatga aagtttctct gggtgtcgta
    24721 tcacctaaga ctggtctcat tacagacgtc aaacaacttg aaggtaaaac cttaattgtc
    24781 acaaaaggaa cgactgctga gacttatttt gaaaagaatc atccagaaat caaactccaa
    24841 aaatacgacc aatacagtga ctcttaccaa gctcttcttg acggacgtgg agatgccttt
    24901 tcaactgaca atacggaagt tctagcttgg gcgcttgaaa ataaaggatt tgaagtagga
    24961 attacttccc tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg caaccaagaa
    25021 ttgctagact tcatcaataa agatattgaa aaattagcaa ggaaaacttc ttccacaagg
    25081 cctatgaaaa aacacttcac ccaacctacg gtgacgctgc taaagcagat gacctggttg
    25141 ttgaaggtgg tcattaactc ttaaaaggga ctggatttta agctccaatc cctttttaag
    25201 attttaccta taacatcctg agtctatcta agatgttcaa tctgaacaca gtgtacatac
    25261 tttatcttct attgcatata ctttatcaca taagatacga atatcctctt cactatgact
    25321 agcaatcaaa attgttgtcc ctttttcact agagagcttt ctaaacaatg ttctcatatt
    25381 ttctacactt gatttatcca aggcattcat aggttcatct agtaaaagaa tagagggatt
    25441 ctccatgatt gcttgagcaa tccctagctt tttcctcata cctagcgaat aagttttaac
    25501 tttctggtct ttttgctcat atagaccaac tattttcagt gtatcattga tttcctgatt
    25561 accaactact cctcgtatgc ttgccaaata ttgtaaattc ttaaagccac tataataatt
    25621 tataaaacca ggttcttcaa tcaaagctcc caaattagct ggaatttttc tctcaggaac
    25681 aatattttcc ccattgatta acacttctcc ataagacgga ctatataaac cagctattaa
    25741 tttaaacaat acacttttcc ctgagccatt cgcaccagta attcctataa tttccccctg
    25801 tttacaacta aagttaaggt tttgaaaaac acatgtcttt tttaatttca actcaatatt
    25861 ttttaatata attatttcat tcattctata aacctcctct tttgacgagt gaaatagaaa
    25921 atgctttgaa aaagaaagac taaaaatagc aactgaagaa acaaatctcc ccctacatcc
    25981 ccattccctc gattcaaaat ataaaataga taattagttc gatttcctac aaatagacca
    26041 ccaaacacaa tcatgagtaa aaagaaacta acgcaagcaa agttcatttg tacattcgct
    26101 cctagtgcgt ataacataaa gcaaaacaag actaacacac aagcattcaa agaatcaact
    26161 ataaacaaaa ctcctatatc ccagtttggt aactgtaaca taaattgaat cactagaact
    26221 tttaccatga ttaaaatgag tccataaaga aaacaggtcc aaatctgata cctaatccag
    26281 agcttaatag aagaaaatcg aatcacttcc ataaagaaat cggatgctct tctacgatat
    26341 acaactgcta gaaaaaatgt atgaataata aaccaatgaa gcaaccatat agataagact
    26401 aaaaaagagt tttgactcag attaggccct tttaaaattt ctataacaag tctatcattt
    26461 ccttctaacc aataccataa tcctaaacaa atcaatatcc aaaaaagaac ataaccccaa
    26521 aagtacttgg tatagattat cttattcaac ctccacatgt gactacttaa ctttcccatt
    26581 tccaactttt acactctcct ccagtttcta tgaacagaaa atacagtcaa tggaattatg
    26641 atagatagta atgtaagcca ataaatcaat gcatacggat tggaatttac catatactga
    26701 aaaattggca ataatccaat tatcccattg ttcaactgat aaatccagaa taaggattct
    26761 acaaataaaa aagtaaacag aaatactaag ctcatgtttg attttttaaa ccaagaaaaa
    26821 ctgctaatag taagtaagga taaaaagaaa tagtatgcta tataagagaa aaaaaatcct
    26881 ataaagaaac tagcattgtt tgcaatactt ataccataaa attctcttaa aaaatcaacc
    26941 tcctttatct ccaaagagaa gctaaaacca ttactaaatg caattagaaa aatcaataaa
    27001 aataaagtcg ccgtccaaat ccccgtacta agagctgcta atttgaaact aaaactggta
    27061 aagtgcttaa ttgatttcag acgaatgcga cactccaacc tattaaaata gttattcatc
    27121 aaataaaaaa agaacaatat atatgtgaac ggaaagcaat atactccagt cgtcatatct
    27181 tgaagtaaaa ctaaaatcca ttctaataca tttggatgga ttgaatattg gcgacagcgc
    27241 aataaatata ctgtactaga taaaacacag gatagcagta atataaaata aaccaatact
    27301 gataaaaaat cttttttgta aaattgaaca aattgtttca ttatacatag tcctctgaat
    27361 gtagaaaaaa tgtaccataa acaaccaaac aactaacaaa taaaataaaa gcaagatgcc
    27421 cactaactaa ggaaagactg atatctttct gatatcccaa agctaatgtt gtcacaggtt
    27481 ctaagtaaga tagccctaaa atagcccaaa aaataccacc aaccatcata taggcaactg
    27541 ggatgaaaat agctcctatt tttttcttca ctagcaaagc actagctagt ccaaaaatag
    27601 agaacacagc gccccaaact ccataccaga gagtcgtcac aagactatag agcaactgat
    27661 tagaatcaaa taattctttt aaggcaccac tataatctcc aatataaatt tcctgataag
    27721 gagtcactaa aagattaatt cctaataata ataaataggg gagaaaaaag actagaaaag
    27781 aagaaataat tgcagtacta cctacaatag ccagatactt ctttttagaa attcggcaca
    27841 attgtgctgt tagaaaatga ctctcagcat cctctattat ctgactagaa tagggcagtg
    27901 tacagataag tgcagctact aggctaatcg gtgaaaatcc tcgaatagaa gaagcggcaa
    27961 aaaaaatcga taaaccttca attttataaa taccattgaa agcaaggaaa tttcctaaac
    28021 tcatgcaaag aagggtcaaa aataaagaca tataaaatcg aggtgattga acgactcgta
    28081 caagattaca aatgaaaaat tccatcctta ctcctcctta taataaaaat agggtgtagc
    28141 attctttttt catgctacac ccacaatcaa ccatctttaa ggcttactct gacaagtaag
    28201 ttaataagaa tctggactcc aagaacctga agtatgaatt cttacatgat ttccaaattg
    28261 tggcgccata gctaatctag taccagaacc aatataattg tcaccacctc cattatagta
    28321 catgacaatc ctagagccag accccaatga atataccggg gtaatatctg acccactata
    28381 ggcgctacga atagaggtat ttaacctttt accgccacca gtgctgtcac tattattaat
    28441 tccagcagag gcgttttctt tctcaagctc actagttgta tccgaacccc aacgcggcaa
    28501 cgttaaatca taatttccaa tctgtctagc taaaactgta gggagaaaca aactagatgc
    28561 aattgtaact acgcaaaaaa ggaatatatt tttcttcttt tcatgacatc gtcctcttaa
    28621 gaagtgataa acaagatagt tgattgatca atttgataca tattacattt tcattatatc
    28681 aataaaagaa agcgttgtca attattttat ttaaaatatt gtcatatttt aaataaaatg
    28741 gtaaaagaga ctcggtagcc tcgtctctct ttatcttact gacctaacct tcttgccaat
    28801 tttcttggtc ttctttaaag cgttttagaa gatcaaggcc ctctggcgtg atgtaacctt
    28861 cttcttgggc tagatggata agctctctat agtttgaaag cgtcacaagt ttaacaccag
    28921 catctgcaaa gttcttatct gcttttggca attggtagct gaaaatcgct acaactccaa
    28981 gtacatctgc tccttctcgc ttggctgctg ctacagcttc aagaactgaa ccacccgttg
    29041 aaataaggtc ttcaaccact accatttttt gaccttgagc tacgcgacct tcgatttgat
    29101 taccagctcc gtggtctttt ggtttgctac ggatgtaggc aaaaggcaag tccatcttat
    29161 cagcaataat ggctccgtgt ggaatccctg ctgttgcagt tcctgcaatc acttctactt
    29221 caggaaaggc ttctttaata gcttccacaa aaccattttc aattagggta cgagtttctg
    29281 gataggctag tgtcacacga ttatcagtgt aaatcggtga cttgatacca gatgcccaag
    29341 tgaagggttc ctctggtttg aggtaaacgg cttggatttt caagaggtgg ctagcgatat
    29401 ctttagcaag tgtcatggta ttctcctttt atttttctaa tctagttctt taattccagt
    29461 tctgtgtcca ttcatccttg atggcatgat aagctgcaac aggatcctca gcttgggtaa
    29521 tgggacgtcc cactacgata tagtcactgc cgatttgata ggcatcagca ggtgtcatga
    29581 ctcgtttttg atctccaact gcaacaccag ctggacgaat ccctggtgtc agacagataa
    29641 aatctggatt ggtagcctgc ttgatgactt gtacttcctg agccgagcaa acaacaccat
    29701 ccaagccagc ttcagctgtc ttcttggcat agtgaatcac agactcttgc agactggttt
    29761 ggatattttg aaactcctgc atctgagctt ctgacgttga tgtgagctga gttacagcga
    29821 tcaatttggc ttgactccca agaccttcac gcgccgcctt catcatctct acaccaccag
    29881 ccgcatggac attagtcata tcgacaccaa gctgagacaa gaccttcatg gctgacttga
    29941 ctgtattagg aatgtcatga agtttgagat ccaaaaagac actatgaccc aaacctttta
    30001 agtaggacac aatctcaggc cccgctgcgt aataaagctc catccctacc ttgagataaa
    30061 ggctttcttc tgctgggaaa agagctaaaa attccttgac cgcctcaaaa ctaggaaaat
    30121 caagagcaat gattggacga tgttctcgca taggtttctc cttttacctt tactagtgag
    30181 agagtctggc caacagaagc cacgaaaaaa ggaacctgcc aacagcaagg ttccacgaaa
    30241 aatgggtagt ctccaccctt tcaccgtcta accttagctg cctctctgga ctgctttaaa
    30301 ggttttctat tattctatta tttctactag cacttgtcaa gtaaaaactt agtcacgtat
    30361 gtgttgactg ctattgaaca cctcacaaga ctctttccaa aagaatagtt aaagactttc
    30421 acttaggaca gagaaaaaga gtttgcttgt taccctttaa ttgaacaaat gggaattctg
    30481 ttttattttg cggatgccta ttcatcttgg caaaggggaa gtaatgagaa tgcgaatgga
    30541 cttcttcgtg agtattttct taaaccgatt tggcaacaat taccgaaaaa atccttaatg
    30601 gtgctttgct agcttattaa tcaccgtccc caaaaatact tggattacaa gacaggtttt
    30661 gaagcactta tagaggaaat ttaaaaatgt tgcatttttt attgcaattt atcagttatc
    30721 ttatcaccca aaacttctgc aattagtatg agcactattg ttatttttct tttttcgtac
    30781 actcaaatca aaatatagca ataagactat tctgtagaat tgctgtcaaa aagatcagtt
    30841 catttttcct tcccacttgt gtttataatc attaaaataa ctcaattaag aaattttctt
    30901 tttcctaata gttatcgtaa ttaaagttaa tagaagaaca atccaaataa gtagtgttag
    30961 attaggaatt agagttttat tccatgaaaa tccctcccat tttgtgaaaa acttagtaaa
    31021 cagtcccata aaactataat ctgttatctt cgcaactgtc ttatccaaac cagatagcat
    31081 cggtaagaaa gcaactaaaa tcatagcagg aagactgata acctgagcta ctacttggct
    31141 cttcgcggtt aaacctatca ataaatagaa taaaatgatg gataaagagg ttagaagaac
    31201 gattgtaata taattaaaag tatgtacaat tgtaactcct aaaataagag gagtagttcc
    31261 cataatcaca aaagttagca aaaaaggaag aaacatcgtt gataaaatgt attcggatcc
    31321 tttaacacca ctcaacagaa gagtttgtaa attgtacttt tctttttctt cagacaagat
    31381 aatagttata ggacttccaa cagccaaagc caaagaaaaa ggtaaacaca tcatcaaaag
    31441 aactaatgcc tgttgatcgt tgaccttccc ctgtgtttcc ataagatatt tataaaaata
    31501 tgtgaaagca aaaggcacta aaacttgcaa taaaatactc ttattggaaa ggataatttg
    31561 acaacgcaac cataccaaag ccagaaaccg tttaagcatt tagctttcct cctgttaatg
    31621 tgataaaaat atcttctaaa gtaggctcac atgaatgaat tgaaaaaata ttttccagat
    31681 cagcctgaga tacctgttct agtgatgtaa aatcaaaagt tatctgattc ccattataat
    31741 ctgtaacctt aatcttttta tctttattat atctttgaat gagttcagaa ggagctcctt
    31801 gctcaactaa tttcccttta tttaataagg caacataatc acataaaaga gttgcttcat
    31861 tcatatcatg agtcgttaga aaaatcgttg tccctgctgt tttcaattct aaaattaact
    31921 catgaattgt tcgagaagtt gtgggatcta gacctgaggt cggttcatcc agaaagagta
    31981 cagcgggttt gttgataaga gctcgtgcta aaagcattcg ttgcctcatt ccagtggata
    32041 attttcctgc taccatcttg cgactatcat ataatcctac tcgctttaac aaattatcaa
    32101 cacgtgattt actaatatta taaaatttac tataaaaaag aagattgtta tacagagaca
    32161 ttttctcata aaatccactt gtatcgctaa ccaatccaat tctctttaat tcaccgcttg
    32221 ttaaattttg agatttttgt cccaaaataa tagattgtcc tttatcggca aggaactgcc
    32281 cagtcagaat attaatcgtt gtggtctttc cagaaccaga tggtcctaaa aatctaacct
    32341 tctttaacag tgaagcttat attatttaaa gctattttat caccaaaact ttttgataaa
    32401 tggctaactt caatcatact cattgcacct cctttatatt ctacattttt acttaacatc
    32461 tatttactta tctttatcaa ataaacgtct taaaaaaaac aataacatta agcatataac
    32521 cgttagcaag attgtttcaa tattattgat aatacgatac attctcaagc agtataaaat
    32581 aattatatat atgcaaatgc tcattatacc tattttttta aacatactaa gcctccttgc
    32641 taaataataa agttatataa taactaagac acactatacc taacataata aatatccact
    32701 ggtaactgaa taaatgttct aaaattaaca agcaaaaata aaatctcaaa cgatgaaaaa
    32761 agccatacta tattttccaa tgatgtttga atatttttat tgtagtaagc ataatatata
    32821 gcaaaaataa tacccaagaa caatactatt aattgtgttt ctataacagt gaactgccca
    32881 atagcagata aaaaagctac tcctcctgat aataagcaaa aacaaactga acgaataaat
    32941 gttttcgctc taatattgtt atctttcact ttattatttt tttacaaatt ggacattctc
    33001 cgttttccag aacatatttt tcttgactta gagcatgatt tctcatatta taaacgtaag
    33061 cgttatctat taggatttca ttataacatc ccagaaatat tttaattatt aaattagtca
    33121 ttatccctcc caaaatagca ggcatctctg gtgtagtcgg ccactttgtc ttatcagata
    33181 aagtgtactt atttatatct ttgtttatat tccgacaacc aaagcaagaa ccgatggtag
    33241 ggatatatat tatcagtaat aagatagcat ccattaaacc ctcctgatat gtaggatatc
    33301 ttatgcgata cagcaaattg attgacaatt tttataatat caatgggcgt atcaattgct
    33361 ttaacgataa aatctatact cccatattcc gcaacaattt tttctaattc ttctactgaa
    33421 gaaactttaa tagaaatagg tactacctga acatctgaat tatacttgtg tattttttca
    33481 gaaagaacat taatcttctc cttaccaaca tccgactctg tataaagaat ttgcctattt
    33541 aaatttgatg gttctattat atcgtaatca gcgacaataa gtttcctcac tccatacata
    33601 cttagactta gagatatata acatcctaag gctcctgctc ctaatactaa tactgtttta
    33661 ttctgtattt tattatactc ttcattataa aataacgaat agtaaccttt agttctagaa
    33721 tatctactat caatatctat ctcatccgaa attaaaattt gttcatttaa tagttcaaat
    33781 gttagtttac tgcctaatac ttcttctatc tctaatagtt ccttacaact attaaataga
    33841 tcgttgataa attcttgcga aatttgaggt tctatagcta tttcccgcat actccgacca
    33901 cgcaaataca ttataccttc ttttttataa gcaaaaacat aactatttac gtagaacata
    33961 tttcgtcctt cctctcatat ataatataga aagcagtata gaaacaacca cccctcctat
    34021 actacgaaca ataatattag gtgtcaaaaa ctgtaatagt tgactcaaag ggaaataaat
    34081 aataacaaat gctattaaaa gttgaactat atattgaaaa ttcaagttat tattgttaga
    34141 attcaagtat cttaaaataa taccactatc atactgaaaa aaaggaattg aattaataaa
    34201 aatcatacct aagttaatga taaaaaataa gagtccaagc aatttatacg atgtgaacaa
    34261 taaaacaagt aaacctgtaa gtgataaaat cgaatttgaa gcaattcctg ctaacataat
    34321 tttcaaaaat tgttttttat tttttaagaa ttgcacccca cttaaatcta caaaaaaaag
    34381 ccaaattaaa caaaagtagc attattccac aatttgggat ctcaatttga taattattag
    34441 caattattgc atgactaaat tcatgtatcg ttgcagacat aataacaaca agcaaccaaa
    34501 ataaaagaat gtttagcgtt attggaaagt tttggaaatt agtcaaaata tccgccctat
    34561 aaatatacat aataaaacat tgcaaaataa gagccaatgg gaaaatacca aataggattt
    34621 tttcaaaatt cttattaaat cttttatagt ttaatttttc agataatgtt atattaaagt
    34681 cccaagatat tttaaaaata tttatctttt ttcgtgattt catagaatct ataagtccca
    34741 ttttactaag aacaatataa aatcttaaat aatatttctt ccctactaac actaataagt
    34801 ccgatatggt aaattcttga cctattagtt gctctaacca tttttttcct gtttcccaac
    34861 taatacatgt ttcttactag atggtatata tagatgatac tgtccctcat aaggagtagg
    34921 taatatctta atcttatcaa caattctcat aacaaaccta acctttaata aataaaagag
    34981 gggctaagta aaacatactc tagtccctca gtccgcaatc aataaaataa tgactaattc
    35041 tattaatctc ttgctgcaag actaatacgg aaaattcaaa tgactgtcta aaatgaaatt
    35101 gaaaaagctt gatgttagta aatgaacaaa cttcaacaac cagcaagagc aaggattgct
    35161 aaaccaaatc cgatacctgt tgcaagtcca gctgaaaaat cactaactgg tactgaaatt
    35221 tcttcaattt cctcaaataa aaagttatct tgcatgatta tcactcccta tctttttaac
    35281 aacaggctat tccaattaag agaactaccc cagttccaag taaaactccc ccaaaaattc
    35341 accatctgta ggggctacga tttcttcaat ttcttcaaat aagaatgctt catctgacat
    35401 atgtgttacc ttcttcataa aaaattattt tgtaatcgat tacattgcaa atgtaacata
    35461 aagaaaaaca gatgtcaaat attaaacgta agaacatggt cactaaagaa ctataagaga
    35521 aaaggtaaac ctagcgacgc gatgagcgct gggtcgtttg atttcgattg ctctcttcct
    35581 cttgtttttt ctgttcttct tcctgttttt tctcggcttc cttggcctct tgtttggctt
    35641 tttcctcagc ctccataatt aatttatccg ccacagtgta actgtaaatt ccagcttcca
    35701 tgtcgaccac actcggttct gacaattgtg gcttaatctt actgtaatat ggcagtttct
    35761 tactcatttc agatagagga accaagactt cgtccgaatc attcatggtc aatcgaatta
    35821 aatcggatgt caccttgctt ggggctaatt ccaccttttg gatagccgcc ttgagttctg
    35881 ggctaatttg agcaagttct gagacaaaaa ccttgatttg ttcactatca ttaaagagaa
    35941 ctgataaata agtttctggt aaactgttca gactcacaga actagtctca agctgaccac
    36001 tggaaagaat aggataatga ttttcaccag aaatatagta ggccacaata tcatattcct
    36061 tgaccttaat agtgaactta gttggaaatt gatagacaag ttgagctgat tcaacccaat
    36121 agttagactt aatctgcttt tcatattttg ccttgtctag cagaaggtta atcgtataat
    36181 ccgaatcctg aatgcctgaa gcctgtcgaa tatcatcagc tgtagtttgc accgttccct
    36241 caacacgaat atctttcatg gtcgcataag gactgagcaa gtaggcagag acaatcaata
    36301 aaagcagact tggaaataaa atcgtgaagg ctcgcaagat atggatacca ggaatctttg
    36361 ctttggctgg tttttccttt gtagcctttt tagaaagctt tttatcctgt tcctccttct
    36421 ctttagactc tggttcttct ttctcttctt tctctttgtc agcctctgag gatgctactt
    36481 tttcttcaga ctcttcctta gctgattctg aatcttcctg gtctgtttca ctctcctggt
    36541 cctgtttgtc ctctgacttc tcagattctt ctcccattcg agcttgtctt tccttttcct
    36601 tctcctcagc tagagccgcc tcttcttcag ccttcttttt tagatattct tggtttcgtt
    36661 tctgccattc tgataactct ttcaattctt cgaggatttc tttgtcctca tttttcttat
    36721 cttttgacat ttactttcct tatgataaat cttttttcaa caattgataa aaatctgcta
    36781 gagatttcaa ttccttagaa gccttcatct tagcttggta atcttccttg tgacttagta
    36841 agtgagaaag cttctcttcc aaactatcca aggtcaaatc gctttcttga aggtcttctg
    36901 catagccttt ttttacaaag taagctgcat tttcaagctg gtcaccacga ctagcttcac
    36961 gaccaagcgg cacaatgaca tgcaattttg ctatcgccaa gagctcaaaa atcgtattgg
    37021 caccacctcg tgtcacaaca atatcagcca attccatcaa gggttgatag agatcggtca
    37081 catagtcaac acgaaaaaga ttttggctca actcattcag gctagaatct ccagttagat
    37141 tgataatatt gtagcgctct gttagttctt tcttatggtc tgtcaccaat tggttaaaga
    37201 cacgagcacc tgcagaaccg ccaacaaaca atacagtcgg caatttatga ttaaagtggc
    37261 tttgaatatc caccaattca tctggttctg gatttttttg atctgaaacc ttggccactg
    37321 ctcccacatg ctcaacctta gacaaactcg aagcttgctc aaaggttgaa tacatcttag
    37381 tcgcaaattt ataggcgatt ttattggcca agcccataga caggtcagat tcgtgaataa
    37441 agacaggcac tcctgacaca cgcgcagcga taacaggcgg tactgagaca aagcccccct
    37501 ttgaaaaaag ggtctgtgga cgaagtcgca acatgataaa gagcgattgg acgattcccc
    37561 agcaaacttt gaagacgtcc agcatatttt gccaagagaa atagcgacgc aattttccag
    37621 tcgcaataga atggaaggtg acatccaaac ctgacttaag gatttcttgg tgttcgatac
    37681 cacgcttgtc cccgatatag tggacttccc aaccatcttc gatgaacttg ggcattaaca
    37741 aaagattgag ggtaacgtgt ccaaccgtcc ccccacctgt aaagacaatt tttttcatat
    37801 tattctttta actccgctac tgtgtcgata aagaggtcgc cacgtacttc aaagttagca
    37861 tacatatccc agctggcatt ggcaggacta agaagaacca catctccttg agtcgcaagc
    37921 tcataggcct tgcgggtcgc atctgcaata tctgtcgcct ccacataagc gacaccagcc
    37981 ttgtctgctg cccgtttgac acgttctgca gattgaccca ggatgaccat cttcttgagt
    38041 ccagtaatgt ctggcaccaa ttcgtcaaac tcattgccac ggtccaaacc acctgcaatc
    38101 aagacgacct tgctgttatc aaatcctgac aaggcttttt gagtagccaa gatattagtt
    38161 gatttactgt cgttatagaa tttaacaccc ttgatgtcat ccacaaactg gagacggtgt
    38221 ttgacaccac cgaaggctga aagagtttcc ttgatggttt gattgtccac accacgaagc
    38281 ttggctacag caatagtcgc aagggcattt tccacattgt ggctacctgg aacaccgatt
    38341 tcattcgctg ccatgactac ttcaccacgg aagtagagtt gaccatcttc cagataagct
    38401 ccatcaacct tttcaagtgt tgaaaatggt acaacagtgg cttctgtctt ggaagtcaag
    38461 tcttttgcca agtcttgatt aaagttcaag acaaggaaat cagctgctgt catcttgttc
    38521 tggatattcc acttggctgc tacatattcc gaaaatgacc catggtagtc gatatgagtt
    38581 ggcatgaggt tggtaataac cgcaatctct ggatggaatt cttgaacacc catgagttgg
    38641 aaagaagaaa gttccataac aagcgtgtcc ttatctgatg ctatttgagc aacctgacta
    38701 gctggatagc cgatattccc tgataaaaga ccatgttgcc cagcagcagt caaaacttcc
    38761 ccaatcatag tcgttgtggt tgtcttaccg ttcgatcctg tgataccaat aatcggtgct
    38821 tctgaaatca aataagccaa ttccacctca gtcaagactg gaattccctt ggccaaagcc
    38881 ttttcaatca tgggattgtt gtaggggata cctggatttt tcaccataag ggcaaactct
    38941 tcatccaaga gttccaaagg atggccacct gtaatgacct tgatcccttc ttccagcaaa
    39001 ctttgggcag ctggattgtc ctcgaaaggt ttcccatcat ttactgtcac aatggcacct
    39061 agcttgtcca acaaacgagc tgcagattca ccagacttgg ccaaacctaa aacaaggact
    39121 ttcttatttt taaattgatc tattactttc atgtctcgaa ctccatttct actcctacta
    39181 ttttaccatt tttatggaaa taaaaaagcc acaaagtgtg tttgtgactc tttcttctaa
    39241 ctgaatctta ccatatcatc tatgtgataa atcggtaact cgaatgacct gatccacttg
    39301 ttcccaaata agaggattgt gggtcgcaat aataatggtc cgattcggat tttttaaaga
    39361 ttctaggatg gaaagtaatt cctcagagtt tttggggtct aaggaagtgg ttggttcatc
    39421 tgcgaggatc aaaggtggat cctttaaaat tatcttcgct aatgcaacac gttgtgcttc
    39481 tcctcctgat aactcaaata taggttgctt caaatccaaa taagagaggt ttacacagtt
    39541 tagagcttgt ttcatcaaag agattttctc tttttccttc aactttttac caactaaacc
    39601 cagattgaga ttctctttga cggtttggct ttcaattaag ccaaaatctt gaaataagta
    39661 tcccaagtaa tctctaaaga aaacagaagg cttgatgtcc ttaagagaag taccatcata
    39721 gatgatttgt cctttgtcat atggctctaa tcgtccaatc atattcaaga atgttgtctt
    39781 accacagcca cttgtaccga ttaaggcata aattttccca ccttcaaaat gaagatttgt
    39841 atctgaaaat agctgacggc ttccaaattt tttagatata ttctttagtt caatcatcct
    39901 attttccttt cataattgtc atagaaacac gagattcttt ctgcgcttga cggtaaagcg
    39961 tcagaactgc actagctaga aagactaata aagtgagcaa gccaatcacc aagtctcgac
    40021 tgcttaaaat aaagagacta gcaccaaata caaaactggc aaattgacta accatatact
    40081 gagcatgtgt ttcaaaaaat cgtaaacctg aaattcgttt aatcaaaata tctcggcgga
    40141 attgctcgaa atatagaaga ttgacagaat aaaatagtaa taaggaacta gctatcccca
    40201 caatagctcc taagattaaa gttgctgttt cagtttgaac ttcattataa cgagttagat
    40261 aaacacttct tccttcttta agataggata cttgctcata aattccagct ttcttcaaga
    40321 gttctagccc actctcatat cctttgataa agagttgttt tccagcattg atagaccaac
    40381 tagataagga tataaaacta tcacctgtag aagtcggcgt gaataccact aaaatcggat
    40441 cagtcaaata ctgagtagat acgggattct caccgttatt ataaacaaac cgcttttctc
    40501 ccattgaaag ataactaacg tgcgctttca tctcataatc caaaggagca cttgcctcct
    40561 caccagattt tccataataa ctcaatcttt cttcaaaaac tttcttaagt tctgcttctc
    40621 gagagcgcaa atgttctggg agcaagagga taaactcacc tttttggaga tgggctaact
    40681 tctgtttggt ctcagcatct accacgacct tttccttgtc caaataactg ggactaacat
    40741 agagcgtatt agcatctgga ctataggtat ccagtgtctc tccctgttca ttttttcctt
    40801 gtggattggc aaaatggagc agattatcct ttacataaag agcttgttct tcttcgattg
    40861 cttccttggc aaaggcatac cacttgctct gattttctgt atcttttcct ctatcaccta
    40921 agccaaaaga aatttgataa tagtctgctc tatcctgcca tgcttgtttt gaaatttcaa
    40981 gttctttcaa tcgttggtaa gacatcaaac ctgtcttaac agcgtagcct actgtaaaga
    41041 cagcaaccaa ctgacacaat agggttaaaa tcatcaggcg tttaaggggt aatctcccct
    41101 taataacggg aactaatgct ttgtaactca aactcattag ataaagaagc attagtaaaa
    41161 ttgaaatcgc caataaaaac aacagataga aactaatccc aaaaccatag gtggctaaca
    41221 agataggata aaacaaacct tgactaaaaa gaacgactcc cccacctagg aaggaaagga
    41281 gggctgatag aaggagccat ttgatatcag tagataaaga atgccccatg atggataaga
    41341 gagtctgacc agaaaagagt tttatacctg ctgctctcat ttccttaatc cgagtgataa
    41401 tcactaaagc aaagaaagat aagccaaata ttgctaaact aattaaaata aggggattta
    41461 gtaatattcg aaaagcaaga aaatagggcg gtatctttcg gtcagcactt gctttataac
    41521 ccaaatctcc taatttatcg gcaagctttt ctttcgtcaa ggagcctgac aaaaggagat
    41581 aactatttag cggatcacta cgttcacgac tttcttggct agcttcttgg aattcttttg
    41641 gtaaagttcc ctgaccataa gttgcataag taaagtgagt cgtcccatcc ttactcggct
    41701 ctacaattct tctagctatt aaactctgtt ctgagtttgc aaaattctcc aattcctgtt
    41761 caaatacctc acgcgtcggt tcctgagtat cttttttgac acgaagtaaa gaaacggaat
    41821 catagcttgc atataaatat tgtggcgcac gtaagacaat aatccaagca aggaagaagc
    41881 tgagaaaaaa agttgataat aatatgaata gtttcttcat agtagactcc ttgtaaacaa
    41941 aattccccct gtaatttctt acaaggggaa cgatttaaat caatgaacga ttagtcataa
    42001 tcacagtaaa atgctacttg ttctccccat ttagtccaaa tccatgcata ggaggttttt
    42061 ccagcagaag cttctccttt atctgaatga ctattccatc tacttacaag agaagaataa
    42121 tgatattttt taccatgata gtaatttgaa aaagcccaac cacctcctga accttctcca
    42181 tacgtccata ctcctccatc tggatattgt acagcagctg atgcagctcc caataatgta
    42241 aaacttgaaa taagagctag agcaagtaat ctatgttttt tcgttttcat tttatttttt
    42301 ctttcaaaaa aagcacacct tgagcaacaa tgcaacaaaa taaaccctcc tctctctttt
    42361 gttgaaaccg ctttcttatg tgataaaaat atcattttta ttatttgttg tcaaggaaaa
    42421 aatcgaattt tttagatatt ttactacatt gcctctatga ataatattat atagtagttt
    42481 tattttaaaa taatatgcaa ccagtactaa ccaaatataa aatagatgcc attaacgaat
    42541 tttattcaag tttttcccat tcatactatc caagcaaaag agatgatgtt atagtacaaa
    42601 acaattcaaa ctattgtaaa attcctagca aaaaagagag ccaaaactct cttttttatc
    42661 ttcttttact ttttttgact ggcatgagtg taatgtctct aacactaaag taagctagga
    42721 tcaacatggc tattgctagg aatatttctg ttggtaattg aaaaattttc agaaaagata
    42781 gaaccaataa aatcaagagt gccactaaaa tacataccat agcgacgata ttgactgtcc
    42841 ctttaatgct ttctggtgtc gcaaatacat agagtaggag cagtaaaatt cctaggacta
    42901 aatagaccat ctttctctct ttctagctct tattcagctg attttttctt cttgttagct
    42961 ttctcacgct ctgctttgtt aaggatttgt ttacgcaaac ggatagactc aggcgttact
    43021 tccatgtact catcgtcgtt caagaactca agagactctt caagtgtcaa gatacgaggc
    43081 gtcttgataa cagctgtttg gtccttagta gctgaacgaa cgttggtcat ttgttttgcc
    43141 ttcgtgatgt taactgtcaa gtcattttca cgagagtttt caccgatgat cattccttca
    43201 taaacctcag tacctgggtt gacaaagatc gtaccacgtt cttcgataga catgattgag
    43261 taagttgtag ccttaccagc atcgatagaa acaagggcac cacggtgacg tccaccaatt
    43321 tcccctggaa tcaatggcaa gtattggtcg aaggtatggt tcatgatacc gtaaccacga
    43381 gtcattgaca agaactcagt tgagtatcca atcaaaccac gcgctggaac aaggaagacc
    43441 aaacgagttt gaccattacc agttgaaatc atatccaaca tttcaccttt acgttcagaa
    43501 aggctttgga taacagaccc ttggtattct tctggagtgt cgatttgtac acgttcaaat
    43561 ggttcacatt taacaccgtc gatttctttt acgataactt ctggacgaga tacttgaagt
    43621 tcatagccct cacgacgcat tgtttcgata aggattgaca agtgcaattc tccacgtcct
    43681 gaaacagtcc atttatctgg tgaatcagtt gggtcaacac gaagggaaac gtctgtttgc
    43741 aattctgcct gcaagcgttc ttccacctta cgagaagtta cccatttacc ttctttacca
    43801 gcaaatggtg agttgttgac caagaaagtc atttgaagag ttggctcatc gatgtgtagg
    43861 attggaagag cttctactgc atctgtcgga gtgatggttt caccgacaaa gatgtcttcc
    43921 atacctgaaa cggcaatcaa gtcacccgct ttggcttctt ggatttcacg acgttccaaa
    43981 ccaaagaaac cgaagagttt tgtaacacgg aagtttttag ttgtaccgtc aagtttagaa
    44041 agggtaactt ggtccccaac cttaactgta ccacggaaga cacgaccgat accgatacgt
    44101 ccaacgaagt cattgtagtc caaaagtgac acttggaact gcaaaggctc atctgagtta
    44161 tctactggag ctgggatatg gtcgataatc gtgtcaaaga ttggtgccat agtcgcttct
    44221 tggtcagctg gatcatctga caatgaagaa gttccgttga tcgctgaagc ataaaccact
    44281 gggaaatcaa gctggtcgtc atctgcacca agctcgatga aaagttccaa gacttcatcc
    44341 actacttctg ctggacgagc tgatggctta tcgattttgt taacaaccac gattgggaca
    44401 aggtcttgtt ccaaggcttt tttcaatacg aaacgagttt gtggcatggt tccttcatag
    44461 gcatctacga ccaagacaac accgtcaacc attttcatga tacgctcaac ttctccacca
    44521 aagtccgcgt gtcctggtgt gtccataatg ttgatacgag ttccgttgta agcaacggca
    44581 gtatttttag caaggatggt aatcccacgc tctttttcga tatcgtttga gtccatagca
    44641 cgctctgcca attcagtacg tgcatcaagc gtttctgatt gtttcaataa ttcgtcaacc
    44701 agggttgttt taccgtggtc aacgtgggcg ataatcgcaa tgttacggat atcttctctt
    44761 aattttgtca tgatttcctc tataatattc aaaatttatt ttctaactga acgattatac
    44821 cataatttca aataaataac ataactcaag caagtgtaaa tgttttcact ccgcttttct
    44881 tttcacgtca agccttttca aagcaagcga cttatgataa gataggcaca gtatgcgttt
    44941 agataattta ttagcccaag aaaaagttag ccgaaaggcc atgaagcaag cactcctcag
    45001 aggggaaatt ctagtcgatg gttgcccagc ccgatcccta gctcaaaata tcgatacagg
    45061 actacaagaa ctcctttttc aggatcgaat cattcaaggc tatgaacaca cctatcttat
    45121 gcttcataag cctgctggtg tcgttacagc caacaaagac aaggaacttc cgaccgtcat
    45181 ggacctgctt ccatctgaca tccagtctga caagctctat gccgttggcc gactggaccg
    45241 agatacaacg ggactcctcc tcttgaccga taacggtccc ttgggctttc agctcctcca
    45301 tccccaatat catgtcgata agacttacca agtccaggtt aatgaacttc taacacctga
    45361 ccatatccaa gcctttcaaa agggaattgt ctttttagat ggtactgtct gtaaacccgc
    45421 aaaactagag attctatctg caagtccctc cctcagtcaa gcctctatca ccatttcaga
    45481 aggaaaattt catcaaatca agaaaatgtt cctctcggtt ggtgttaagg tgactagcct
    45541 caaaagaatc caatttgggg acttcacatt gaacccagat ttagcagaaa gtaactaccg
    45601 ccctttgaac caaaaagagt tacaaatcat taaaaactat ttagagatga gtcgataaaa
    45661 caaaaaaagc tttaaaacta aagctttttt cttttattta ccgaaaaatt aaggcgattg
    45721 ctacaatcca gttaactaca gaaatcacaa ttcctaagat attaagaatc ttttctattt
    45781 tatagtctaa ttgtgactct ttttggtatg aaatagccaa gaccaatcct atgataccca
    45841 aaatcaagcc tacaattgga aataacaaac caagaataat cgacaagata cccacaaaaa
    45901 gtggattttt cttcttttct ttcatgttct aagaactctt taaattttat acaaattaat
    45961 tatactataa aacaatagct tcatcctatc attcgactaa tttggaaata aggttagcta
    46021 gtcttcactt tccctttcca agaatccaag ccataagaaa ggatataaat ctcagaaaaa
    46081 ccttgttttt tcaagtaaag agctgcattt gtaactcgtt gcgcacgttg gttctcgtag
    46141 agaaggacag gtttatcttt acgaagggct gcaagactag ttttcaactg acttgaagga
    46201 atattgcgtg caccaaggat atgttttctg tggaattctg ctgggtcgcg caaatcaatc
    46261 aattgacccg tacgaatcaa ggcttcaaac tcctcattgt ccacaatttt agccgcacga
    46321 cgaatacgaa gatagttaaa gcccatccac gccaacattg ctagtataag tgcccacaaa
    46381 atccaagtaa ccattagttc ttttctccat ttttctcaat ataatccaat tctaccttgt
    46441 gctctctgcg aagaactgct tctgcctcta gatagtctaa tttatccatc aaccctgcat
    46501 cgtaaatccg agatagttcc aacttcatca gttcaatatc atataagcgt tttcccatgt
    46561 aaacaataat accaaatcgt ttgaggaatt gctgcacatc atagaatgtt ttcataagac
    46621 tcattctagc aaaattttgt gtttttttca agaagagact cacacaatgc tccttatttt
    46681 cctatcttct ttggcgattc taaggcaagt gtggtacaat aaaaacatga gaattcaaca
    46741 attacattat attatcaaaa tcgtcgaaac tggctctatg aatgaggcag ccaagcaact
    46801 ctttatcact cagccaagtc tttccaatgc tgtgagagat ttggaaaatg aaatgggcat
    46861 tgagatcttt atccgcaatc ccaagggaat caccttgacc cgtgatggga tggagtttct
    46921 ctcttatgcc cgtcaggttg tcgagcaaac tcagcttctg gaggaacgct ataaaaatcc
    46981 tgtcgcccac cgcgaactct ttagcgtttc gtctcaacac tatgcctttg tggtcaatgc
    47041 ctttgtctct ttgctcaaga aaagcgatat ggagaaatac gagcttttcc ttcgtgaaac
    47101 tcggacttgg gagattatcg acgacgtcaa gaacttccgc agtgaggtcg gggtcctctt
    47161 cttaaacagt tacaaccgtg atgttttaac caagatgctg gatgacaatc acctactagc
    47221 ccaccatctc ttcacagcgc aaccgcatat ctttgtcagc aagaccaacc ctctggcaaa
    47281 gaaagacaag gtgaaactgt ctgatttgga gaatttccct tacctcagct atgaccaagg
    47341 gacgcacaac tccttctact tttcagaaga gattctttct caagaacacc acaagaaatc
    47401 cattgtggtc agtgaccgtg ccaccctctt taatctcttg attggtttgg atggttatac
    47461 cattgcgaca gggattttga acagcaacct aaacggagac aatatcgttt ctatcccact
    47521 ggatattgat gacccgattg agctggtcta tatccagcat gagaaaacca gcctatctaa
    47581 gatgggcgaa cgctttatcg actatctact agaagaagtt cagtttgata gttgagaaat
    47641 gataagaacc aatatgtagg ctagcaacaa cctgcacatt ggttcttttt acttataatt
    47701 aaaagtttcc cctgccaact tatcagctag cttgggaaag agagtataaa acttatgggc
    47761 taggttcaac aaaatcggga gattgagttc tcgtttattt tttcctataa tcttgacaat
    47821 ctttttagcc actgcatctg cctctaagag gaagcggtca accgatttaa gataagttcc
    47881 atctgggtca gcttggtcaa aaaatcctgt tcggattgga cctggattga ctgttgtcac
    47941 atagactcca tagggcataa gttcgagtcg cagagcattt gaaaaaccaa tagccgcaaa
    48001 cttggtcgct gagtaaagac tagacttgcc agtagctatt agacctgcca tgctgacgat
    48061 gttgatgata tgccctttgc tgctttcctt catacgagcc gcaaggtgac gagacagatt
    48121 catcagggca aaggtattga cctcaaacat ctggtgaata tctttatcag caatctggtc
    48181 aaatccctca aaaatcccgt aaccagcgtt gttaatcaag acatcaatct tgccatagcg
    48241 gagataaaga tcagttacca gagcttctag ggctgaatcg tcggtaatat caatttcaat
    48301 caattctgca tgggaataat ttccgtagag ttgggctaat ttttccttat ttctaccaag
    48361 caagatgagt tggtcattgg gcaggagttt gaccatttct tgagctagac caccgctagc
    48421 tccggtaatg agaatagtag gcatacttat cctttctgtg actgctagat ttccacttct
    48481 tccaagtctt tgaccacatg gacattttca aaaattgtgg cagcgtcctt cttgagtttg
    48541 cttatatctt ttgagaggaa acgggcactg atatggttga gtaggaggcg tttggcacct
    48601 gcttctaccg ctacttgtgc agcttgcata ttagttgagt gaccatggtt acgagcaatt
    48661 ttttcatcac ccttgccata agtggactca tgaactagga catctgcatt gacagccaga
    48721 cgcacactgg catccgtttt tcgagtgtct cctaaaatag tgataatctt acctggacgt
    48781 ggcgctgaga tatagtctgc tgccttgatt tcagttccgt cttccaaaac aagatcctgg
    48841 ccgtttttga ttttaccaaa aagcgggccg aacggaacac cagcagcctt gagtttttca
    48901 gcatccagcg tcccttctag atccttttgc atgacacgat agccaacaca gaaaatagtg
    48961 tggtccagct cctctgcata cacagtgaat ttatcggttt caagaatttt acccagagaa
    49021 tcttggtcaa actcatggaa atgaatgcgg tagggcagac gagaacctga cacacgaagg
    49081 ctggttaaga caaatgactt gattccttga ggtccgtaga tttccaaatc tgtctgctct
    49141 tcattggcct gaaaggcacg gctagaaagg aaacctggca aaccaaaaat gtggtctcca
    49201 tgcagatgag taataaagat tttgctgacc ttacgtggtc gaattgtggt ttccagaatg
    49261 cgattttgcg taccttctcc acagtcaaag agccaaactt cgttaatctc gtccaaaagt
    49321 ttcagggcga gacttgaaac gttgcgggct ttagagggct gaccagcccc cgttcctaaa
    49381 aattgaatat ccattcgata ctttctaatt aatcaatata taacatggct gtgcggtttt
    49441 ccgatcggaa atagcgtttg ccagaaaaag cagcagcttc ttgcaataaa tcctcttggc
    49501 tgtagccttt gagacgtttt cgaccatcag ccaatctttc caaatcagtc aaagctgtga
    49561 gactttctag gctgacaact tcctcgtcct tgacaggctt catgtaaatc ttaccagact
    49621 cttcaaagac taattgatgg gagaaaattt gcgcaatttc aaagagcaag tcatccgaga
    49681 ttttctcctc attttcagag aaaatccgac caaagccgtc actctcataa caaaaaccaa
    49741 aggatttacc agacagatta agccgaataa aaggcttatt ttctagggtg aaacttggct
    49801 cagtattgta aagattcagt tcctgactga gttctgcaaa ataatccgtc gcagcctgag
    49861 gacttttttt ctgatagagt tctgcaaagt aggcattaac aacacttggc ggaggtgtaa
    49921 taagtgttaa ctgctcctgc tctgttttac cagctagaag ctgatccaga tagaccttgt
    49981 ccagacttgt ataacctcca tactttagag ccaaagtttt aatatcagtc ataaaattct
    50041 tctaacctcc atttattttt ctcggaaatg tagcctgtaa tcacttcgcc gtcttcctga
    50101 taatcacgtt cttccagaat tgcaacactc tctaaatcat gaatcttgta ggactttgaa
    50161 aaaggcactc gcagggtaaa tgcttcaaaa atttccttaa tcttatctag caataatgct
    50221 tgcaagtttt cacgactgtc ctcagacttg gcagaaatga gggtatatgg cgtttgggta
    50281 ggcgtgaaat cctccaccaa atccgcttta ttataaagcg tcaagtgagg aatatcttcc
    50341 atgtccaggt ctttcatgat ggagagaacc gttttttcat gctcctcgtg gtaaggattg
    50401 ctagcatcga taacatgaac cagaaggtcc acatgcttgc tttcttccaa ggttgacttg
    50461 aaactggaca ccaactctgt cggcaaatct tggataaagc caacagtatc tgtcaaagtt
    50521 acttggagat tgcctcccag atgaatactc ttggttgtcg catccagagt cgcaaagagc
    50581 tcatctgctt catactgggt cttactggtc aagatgttca tgatagttga tttcccagca
    50641 ttagtataac caatcaaacc aatcttaaaa gtgctagact ccaaacgttt ttctctgaca
    50701 gtcgcacgat ttttctcaac caccttaagc tggcgctcga tatccgtgat ttgattgcga
    50761 acgctacgac ggttcagctc cagttggctt tcaccaggac cacgggaacc aattccccct
    50821 gcctgacggc tgagcataat cccctgacca accaagcgag gcaagaggta tttgagttgg
    50881 gctaggtgga cttggagctt cccttcatgg cttcgagccc gcatggcaaa gatatccaaa
    50941 atcaactgca tacggtcaat gaccttaaca ccgagaactt cctctagatt gacattctgc
    51001 cttggggtca gacggttgtt gacgatgaca gtagtgattt cttctgcatc caccataagc
    51061 gcaatctctt ccaacttacc agagccgacg aaggtcttgg aatcatattt ttcacgtttt
    51121 tgtctgtagc tatctacaac gactgcccct gccgttttcg ctaaactagc caattcttcc
    51181 atggagaggt caaaactgtc cataccctgc aattccacac caatcagcag gactcgctcc
    51241 tcttttttct ccgtttcaat catctaaaaa ctcctctatc tggcttaaaa tgcggtcttg
    51301 tacaccagat tctccaatct gataaaaggt gacctgcatg cgattacgga accaggtcag
    51361 ctgacgcttg gcaaaacgac gggtcgcctg tttaagactc tcacgagctt cctccaaggt
    51421 ctgctctcca cggaaataag gaaagagttc cttatagcca attcctttag cagcctgtac
    51481 attaggggaa tggtcaaaca gccacttggc ctcatccaaa agcccagcct caaacatcaa
    51541 atccactcgg tggttgatac gctcataaag ttgactacgt tcatcatcca agcagataat
    51601 cagcggttca tacaaaatct cttgattttc caaatcctga ccaaaatggg caatttctaa
    51661 ggcacgcata gcacgacgac gattaaactg gggaatctca aggcctgctt gctccaccaa
    51721 atgggctaat tcctcatctg aatatggctc caaactagct cgataagcta aaatctcctc
    51781 atgaggagtc tccccaccta ggtggtaacc ttctagcaag ctctggatat aaagtccagt
    51841 cccaccggcg ataatggcta gcttgccacg gctgtgaata tcctcaatag tcatcttagc
    51901 ttctgaaaca aaatcaaaag ccgagtaaga ctcagttatc tctctaacat cgattaaatg
    51961 atgaggaaca gctgcctgct cttctggact agccttggcc gtcccaatat caagtcctcg
    52021 atagacttgc tggctatctc cactaaccac ttcgccatta aagcactttg caacttcaat
    52081 agctagagcc gtctttccaa cagcagtcgg tccaacaatc acaattattt ttgttttcat
    52141 cttttttcct tgaaaaattc ccattttttc gttactatta ttataacaca aaaaggtcag
    52201 tcagaaaaat gtgacctctt gaggaggctg gctgattgag aatataaagg aggaagactc
    52261 atggctaaag gattcgctaa aggtcttgta acaggtgtcg caggaactgt cgctgccgtt
    52321 gcaggtgcag tatacgcatt taaaaagaaa gtaatcgaac cagaagagca aaaagcagct
    52381 ttcatcgaag aaaaccgtaa aaaagcagct cgtcgccgcg tatcacgtta agaaacaaaa
    52441 gaagttggga ttattctcaa cttctttttt ctattctttt aaatagctag gtcaaacttc
    52501 aactgtggct taacagggtc ataatccacc aactcaaaat cttctgcttt gatatcaaag
    52561 aaattagtcc catcaggaac atttaaaacc aagcgtggtt ggcagtttga cggctcccga
    52621 cggagcaatt cctgagcttg ttcaaattga ttatcataga tatggaggtt gttgatgaag
    52681 tagaagaact tcccaacctt ccagccaaaa tgtttagcaa tcatcatctg caaagccaca
    52741 tactgcatag cgttgatgtg gtgggccacc agcatatcat tggagcgctg ggtcaaggtc
    52801 gcatccagat agatttcccc atcaacacgc cgaacatcaa acatggtctg aaaggcgcac
    52861 gggagcagcc catctgtttc ttcgaaagct tggtaatccc agagagaaat aatattgcgg
    52921 cggttccaag gattggtttc caactgtttg agaagcttat tgataatgtc gtgtttctta
    52981 acaacggcac catagcgctc accaatggtt cccgtgtctc caacttccca gtcattccag
    53041 tagtgaacat tgtacttgtc attaagcact tctaagctat ttgactggtc ttggtaaatc
    53101 cagagaactt ctttgatggc ggatttgatt gcaatgggac gcaaggttat gataggaaat
    53161 tctcctttag ataagtcgta ctcggaaaag gcaccagtta catacttgga attagcaaca
    53221 gtcccatcct tgtacttagg acgagcctgc tctgagaaaa caccttcctt tagaatgcgt
    53281 tcaatattct ctttaaaaat cgtatctgct tttgtcattt actctcacct cattcattgt
    53341 cctaactagt atagcataaa aaataaaaga ggaacattac taactctagg ttagcatttt
    53401 cctctctcat tatcttattg caatacaagt gatgctgctc cgataactcc agcgtcattt
    53461 cctagagttg caagagctaa tttagtagat gtgcgtactt gtgggaaagt attttcgtca
    53521 tagacttttt gaacaccttg tagaaggaat tctcccgcag ctgacacacc accaccgatg
    53581 acgattgttg atgggtttag gattgaacca atgttagcac aagcgattcc caagtaacgt
    53641 gagaagttac ggtaaacaat caaagcaagg tcgtctcctt cttttgcgag atcaaagaca
    53701 gtcttagcag ttacttcttc tccgttatca atcaagcgtt tcaaggctgc atcgccttcg
    53761 tattcatcgg catagcgacg agtcaagttg acaattcctg ttgcagaagc gactgtctca
    53821 agacagcctt tcttaccgca agtacatgag attggctggt caaagtcaac agtgatgtga
    53881 cccaactcac ctgctgcacc agcaacaccg tgaagcaatt tgccttctgc gacgataccg
    53941 ccaccaacac cagtaccgag tgtcataaag acaacatctg gttggttatc accagcaccc
    54001 atccagcgct caccaagagc tgctacgttg gcatcattat cgatgaaaaa tggaatgccc
    54061 aaagcttttt caatcttttg tttgattggt tgaagggttt tccagttcaa gttgtaggca
    54121 ccgataacag tccctttgtc acggtcaacc acacctggtg atcccattcc aatgccttgg
    54181 aagtccgctg ctgccaatcc aagcaagtcc aaacgatgtt gaatagactc aatcatatca
    54241 tcaacgatat gacttccctc atccaaaatg ttggtcttga ttgaccattt tccttggatt
    54301 tctcctgctg ttgttaagat tgcaaatttg atagaagttc caccaaggtc aatcccaata
    54361 atcttttgac tcattatatt ctcctttttc attgtgtagt aattgaaaat gcttacagta
    54421 ctagtatatc aaaatccatt cacttatgca aaggtttgcg taaatgaatt ataaggaatt
    54481 ttttcgccta ccagtatctg ttaaccatct aaatgatcaa tggcatattg agctgcatca
    54541 tttgaaaatt tatcaaaatc agaagttaat tgtctataca tacgtttttt tgacatgtgg
    54601 aataacgaat tataactttt tgcctttcct aaagcagcag aatattcact attgctatca
    54661 ttactagaag aagctgtact tgcttgacct tccttccaaa ctccgtcagc gccaacataa
    54721 taacgtccac catcaaccca ttcattgaca gccattttac catccgattt tagatagtaa
    54781 tttccttgcc atgtactata agcataagaa ccatctgatg tcaaataata ccaagcttga
    54841 taggtggcat cataaaccca ttcaccttta gccattttac catctgattt caaatagtag
    54901 tttccttgcc atgcattgcg agcatatgaa ccatctgatt tcaagtaata ccatgcttgg
    54961 taagaagaat cataaaccca ctcaccttgt gccattttac cgtttgattt aaggtaataa
    55021 gctccttgcc atgcattttt tgcataagaa ccatctgatt tcaaataata ccaagcttga
    55081 taagaagagt cataaatcca ttcactctgt gccattttgc catcagcttt caggtaatag
    55141 tttccctgcc atgcattttt cactagattt ccatttccat caaaatagta ccaagaaccg
    55201 tcctgcttaa cccaaccact tgctgtggat gaagttgtat cagtttgagt tgtagccgct
    55261 tgttttgctt taaaagcacc cttaggagca tttttcaatt cgcaagccac accatcatga
    55321 tcgcggtcta acttggcaga ataaccaggt tctccctcat gaagatccga atatccatta
    55381 gcccaagctt ccttacagct cgaaaaatgg atgttttctt ccgccaaaac tggttgtgaa
    55441 aacaaggcta aaattggcaa cgtcaccaga ctcattttta aaaatagacg tttattcatt
    55501 tctttctccc ataattatga tatcgatttc aatattattt tatcaaactt atttcagcaa
    55561 ttcaaggaaa cttctggtct tttctacaaa ctcctttggt tttgccttat tcaagacatg
    55621 agggccatca ggaatgatct gaaactgcga atctgttaac agtctatgga gagctttcat
    55681 agaactaaga ttcggtttat ctttgctgcc acaaattagt aaggttggat aggagcaagt
    55741 ccctgctata tccgttaaat caagtgtctt caattcctca gaaactccga ccataagagt
    55801 cttgtctgct ccctgttttt caaatactct tttgggaagt agtttaaaaa tcagcaactg
    55861 aagataaaat aggatattcc ctgctaattt aagcgggcat cctgacagaa tcaaagctcg
    55921 aagatttggt aaatcgtaac tggaaagttc tagtgtcagg gcagcaccta aggacaatcc
    55981 aatcaaaaca aaaggttctg tctcttgagc taggtgctga taaactcgct ctttagcttg
    56041 ttgatagtta ctaactccag aaggaaataa ctcgatagcc tcagaaggat aatctgtcag
    56101 tagattccga acttctttcc aagactctgc tgactgccct aacccatgca aaaatatcaa
    56161 tttcatctag ttctcctcaa ggcttagttc atacaagcct ctcactgcat tacagccgta
    56221 aatagcttct gcttgggtta aatctgccaa ggtcaagact ttctcttcta cctgtcctgt
    56281 ttctagcaaa tactgacggt aaattcctgg taagattcca agtcggatag gcggtgtgta
    56341 gagttttcca gcgattttca gaaccaaatt tcctatagag gtttcaagca gttctcctga
    56401 cttattgtgg taaatcttct cttgttctcc taggctcaaa tgcggtcggt gagtggtttt
    56461 aaagtaggta aaggattgat tcaaagcagc ttcctgaagg cagacttggg cctgacaaaa
    56521 gcttgtactg agaggggtta atacttgacg attgacttct atctctccag atttgctaag
    56581 gctgattcgc aagcggtaat ctcgattagc ttcacaatcc tgacactctt cctcaatctt
    56641 gtgtcccaag tcttctgcat caaaaggaaa agcaaaataa cgactagctt ttctcagtct
    56701 ttccagatgt tgatcttcaa acagcaggtt cttctggctg atttcccctg tcgtaatcag
    56761 ttggaagcga gcttgtttac gataaagaac tgctgccttt tgatgaacct ctcggtattc
    56821 agattcccat gtgctatccc aagtaatccc tccgccaact ccataaatgg cttgaccttt
    56881 gtgaagttga atggtacgaa tggccacatt aaaaatccgt cgtccatttg gaagcaagag
    56941 accaatcgtt ccacagtaga ctccacgcgg ttgaggctcc aagtccttga taatctccat
    57001 tgtcgcaatt ttcggtgcac ccgttatgga accacaagga aagagtgagc ggaagatttc
    57061 aacaaggtcc acatcctctc gcaactgact cttgatggtc gaagtcatct gccaaacagt
    57121 tgaatactgc tctacctgac acagacgctc cacgtgctcg ctcccaactt cagaaatacg
    57181 gttcatatca ttgcgcaaga ggtccacaat catcatattt tcagagcgat ttttgggatc
    57241 ctgttccaac caactggcct gttcaagatc ttcttggtca gttaccccac gctgagtcgt
    57301 ccccttcatt ggtcgtgttg tcaactcgcg atcattttgc tcaaaaaaga gctctgggct
    57361 catggaaatc actgccatct cgtcatgttc cacataggca ttgtagcccg cctcctgctc
    57421 taccaccata cgattgtaga tggcaaaagg attggcactt aacttttgct tgagttggac
    57481 ggtgtagttg acctgatagg tgtctccctg cctcaagtga tggtgtatct gggcaatggc
    57541 cttttcatag tctgctgcag acgtcacttc ctgccaattt gagggcaaat caatatcctc
    57601 ataagtcaga ggaatagggg aagtttctac gctatcatga acagtaaagt aaagcaggta
    57661 ctctcccagt aggggatcct tgtgaactgc taatttttcc tcaaaagcag gtgcagcctc
    57721 gtagctgaca taccccacca cataataacc ttgctcttgg tagctttcca cttgtgccag
    57781 caaatctgcc acttcttcta catttctcgt tttcaactct ttaataggct gggcaaaggt
    57841 atatctctcc cctaaagtcc taaaatcaat cactgttttt ctatgcatac cttaagtata
    57901 gcataaaaag gcagatacag acaaagctga tctacctttt tacgatttta ttcattctat
    57961 gcttgtggtg cagtaaatag atcaccagag aaaccgtctg tgtttttaag gagagcttta
    58021 aagactttcg atttcaagac aactgtattt cggtatttgt ctttaatact actatcgttt
    58081 agttccgtta aatctttagt aacagcctca tcaaacatag tcttcaactg ttcataggtt
    58141 gaaatttgag tgccattaat ttcaattggt gcaaaacctt ttttagattt tgtaagaact
    58201 tccccatacc attgcttctt ccaatcttca aggtttgaaa attggttatt agaaactttc
    58261 ttaataatga aatcatcacc taatagaccg ttattttctt tattggctgc accttgatgt
    58321 ttgcttgaaa catagtcaat gaacccatgt tcatatccat agtaacccca catacggaag
    58381 gcgttatgtt tgaaggatag agaaccaggg gcaccttgac tcgtattacc gccataaata
    58441 ccagccatca tattaacatt gacatatgcc gtaccaaagt cctctgggtg gaagacctta
    58501 ttacctggat ttccgtgaat ggtcatgaaa ttattattta ccaagtcatc gatggtttca
    58561 aggttagttg ttttctcagc gtctatcaaa tcacgcactt tgtcccattg gtgaggacca
    58621 cttagtttat ttctgtccat tggtcgacgt gtttcgcgat caattttctt gaaccactta
    58681 ctattgtcac ctttaacctt aggaagaaca gcctcagctt ctgcataatc gagcatcatc
    58741 atagcttcat tgtagttctt catgtaatgg tcgatttggt cacgtgtttg aagtttggta
    58801 ggatctggat tataccattg gtttccatca tttgaacgtt caaatgccat atttaatcca
    58861 agtgcgccat attcaccttg atgtccatgt tctgctggag tttgtaacat accttgagca
    58921 aatgcttcaa gatctgtacc ctgtcgatgt ctatgacctc ccagatatgc cattcggtca
    58981 tttacgtggg tagtctcatg tgtaaaggca gatgtgccat attcacttat taaatccgac
    59041 ataacaaaat atacagcatc cataggctgt ggatcagcaa agatgtaagc atacgctcca
    59101 tacccatact tataatcatg atacttatca atacgtccaa agaattcacg aataggtgca
    59161 taatccggtt tatcttttcg atgaccaaat ctatcaggcc aaccaccggg tgcaccatga
    59221 ttatcccata caggagttgg aactacattt tgactcttaa gaagtttatc gcggacatta
    59281 tcagtggcaa ggcgtgacca aaaatctaag taattaactt gctctttagc acgtttattg
    59341 atttcactct tgaacgattc acgtttttct tctgtatctt taccatactt ttcaaacgaa
    59401 ctaaatgaga tagtattata tgttgaaatc ataaataaat gtgcatcttt caagttcaga
    59461 agcgataaaa tcatgcgtcc atgttgtccg ttattaagtc cttcatatag acgatatttt
    59521 ttattagcaa atgcagggtt agttgacggt tgttcaacta cataagcatt attttcaata
    59581 gctttcttaa accaaacatt tatgtctgtt tcatttgtga atagtttcat attgtaggtc
    59641 aagaagtcat gtaagtttcc agaaagagta tttttcgcca ccacttcacg gaaggactcc
    59701 tgtgtacgac ttcccttaat atagtcctct tttgaaccaa tttctattaa tcgatctaaa
    59761 acacttacat tcttaccata aaaatctggt ttgaatagca ttaattcttt aatattgaag
    59821 ttatcaaatt tcacaccgta ataacgattt aggtatgtta atcctaacag gacagcagct
    59881 ttgttatctt caattttctt aatcaaggca cgttttgcag cttcatctgt attcagttga
    59941 tgatcttcat tttcaactaa ttttgtcaca aatgtattaa gatgatcttt tacttcttta
    60001 aagctttctt ctaagtaaag attcttaatt gcattaactc tgttatcccc agttcttcct
    60061 aatcgttgat aaattggatc agattgtaat tcaattggac ttaaaatacc ttcaatagca
    60121 ctaattaaat ctgcacgatc tttaacaacc atatttggtg tatagacgac ttcaccaagc
    60181 tctgcgacac tgtattcttt tacttgctta acttgagagt ctttaggaga aatcgtaaag
    60241 atatcttttg tcttatctgc gtaatgaacc ataatatggt cagcatctgt aaggtctgta
    60301 ataaagtcat tacctttcat tgcagtcaca gacaatactt ctttattcat taatggacta
    60361 tcagttgtaa gcttgttccc ttgattcaca atccattctt tgttgtagaa cggttggagt
    60421 ttttcaacat tacgataaac aagctcacga tttgcattat aatcttgaat tgttttgtat
    60481 tcttcatcac gtaatatacg gcgattcaac ttatcaacca aatgctcagt tacttcaaat
    60541 gtatcagcag tgatacccat atccttaatt ttcttatcag cttctacctg tgaaatttct
    60601 ttaattttag acgattgttt atgggtttta tctccagaac tcacaccgat aactgttgca
    60661 ttattaggtt taatccaatt gcttacaaat tcatcatcca tatcattaga accaaagaaa
    60721 atatcaccac gcttaacatt cactaagctg atattgttat caatggttcc ccaaggccag
    60781 tctttaccaa ttaaaccgcc tacatcacct ctagcaacat caatagtacc tttggctaca
    60841 gaatttctta cattagacca agcaccaaca tctcttggat taaaatcatg agctaaatgt
    60901 cctactatag cacctgcacg agtatttaaa cctttaagtt caacatctgc ataagcttta
    60961 tttaaattgc ctcgataaat ctcagatgca atcccagcca agttccaccc tttatcacca
    61021 acagattgaa cttttccgat aaaagcaaca ttagtcataa tacctgcatc atctaattta
    61081 tccaaaatac ccgcaacatt gttattacca acgatagtac ccgttacttt aatattttca
    61141 acagttgcat ttttcactgt ttgagctaat gaagctaatt gatttgccca aggcatatta
    61201 atattaacgt taattaaatt aatatttttg atagaacccc cttcaactct atcaaataat
    61261 ggacgagcag tgttatgaat ggagaaatgc ttaccatcaa cacttgttaa gtgacctgta
    61321 aatttacctg ttacatatga tttacttggt gtaggtacat ttgttgcatt taaatccgat
    61381 cctaatttaa actcaccgtt aggatttttc tgcatagcat ctactaaatc tttgaagtta
    61441 tagtaaacgt tattttgcga tgctttgggt ttctctatgt aataagtgta tgtttgactc
    61501 aaactattat ttgaatcacg ttggattaaa tcaggagctg aagcagtaac tttaaataag
    61561 gatgtctcct cctcagttac ttcctctata ttagtaatgg caagccttgt tactttatta
    61621 tgattagtgg taatttttag ataatatgac gttagatttt ctggaacagt ttctagaagg
    61681 ctactatctg tttcatttcc attctcatcc actttcatca atcttgtttc tttaatatct
    61741 ttaatctcaa cttttttaag gtctaactga acttctttat cttctaatat ttcagtttct
    61801 tcaccgttac ctcgatcata gaccatggtt gtggatagtg tataaccttg ataatatttc
    61861 aagttgtcta aagtagcttg taagttattt tcttctaccg ttacttcttt aacaactgtt
    61921 ccagtattat cttttagagc tactttaatc gatttaattt ctactccagc tggtttagtc
    61981 aatgtataac tagctgtcgc actcttcttc aagacatctt tatctgtttt agcccattcc
    62041 aaggttggtt tctctaactc ttttgtgcca ttcttaataa ttttgtcttg aggtttttca
    62101 atcactgttt ctgtgatagt aggagcgtca cttgtttttt ctccgcgaat tgttttatag
    62161 gtttcagtaa tttgtttctt atcgtttaca ccttcttgag ttacttgtct tgttccgcgt
    62221 tttaaagtgt catcttcttg ttcttttgtt tcaaaaggaa tgatttcttc tcttgtctca
    62281 accgttgtcc cttcaattgg ttttgtacca cggattacct gttgatttac aggctccttg
    62341 gtgacttccg tactggttga aagaacttgg tcagttttaa cccctcctat tgttttatag
    62401 gttgtttttg taacttgact tcctttttca ccatttcgta ggacagtttc ttcgtccgtg
    62461 tacttggttg ggtcctcagt cgtttcagtt ttatagtcaa gttctgtagt tgattcttca
    62521 acgagtgttc cttcagtcac cttatactca ggtaattgtt ctggaacaag agcctcaccc
    62581 acgtaatctt cttcttgcgt ccccttagct gttttagtct cctcttttgg ttctacagtt
    62641 tcttcagcct tggtatctgg agttgactct tcttgtttcg gtgtctcttc cgctccccta
    62701 tcttctttag gattgtcttc ttgtgatgat tcttttggtg tacttggttg ctcagcttgt
    62761 gtaggttgca cgggttgttc tgggactttt gcttgttcta ctggtggttc aacttttgat
    62821 tcctcagctg gtttgtctga tggttgactt tctggcttaa ctgctacttt ttcctctgat
    62881 tttgactcaa cttctccacc tacttcttca actggagctg gttctgctga atcttctttc
    62941 ccctcttcta ctttaggaag ggtgtcgtca gtaggtttta cctccgattt tggttcttcc
    63001 tttggacttt cttctgttct aggtgcttct tcttttggag tttcctctgt ctctactact
    63061 tggttttctg tcctagcttg ctcctgattt gttgttgatt gaggagtctc aacttcgact
    63121 acagtcacct ctccaggttt tgctgaggtt tcttctaaaa cagtgtccaa gccaagcgtt
    63181 ttgaggatgt cacctgatag ataaccaaca tagcgatagc catccatttc aacaacaccc
    63241 tctcgactag ccagcgctaa ggtcgcaact gggtctacag cccctgcact aggaagaact
    63301 accaatccca tagctccaac tagaaagacg ctagcaattt tctttctctt gtagattaaa
    63361 agcaagctcc caacagtcag caaaccaaaa gctgtcaaaa cagatgcttc tgtccctgtt
    63421 tgaggcaact gatctttttg atacaccaaa ccatatacaa cttcattcct gtcaggcttt
    63481 cctgtctgaa ttaaatcttt agcttcttgt gaaataatct ctttatttac atagtgatag
    63541 gtagctgcgt ccactacaga aggagccatc aaaaggcttc caagaaatac agagcctaca
    63601 actcccttaa tcttacgaat tgaaaaacgg tcttttttaa acactttcat ctcctttatt
    63661 cattctcaag actttctaat agcatcttgc ggatagtgcg cacgcgcacc tccgattaat
    63721 tttggacgac tagccagtgc cgttacatgg gcatgaccaa tctctctcaa aatagggcga
    63781 atcggaacct gaacatgctt gacatgcatg ccaattgcag tgtctccgat atccaatcca
    63841 gcatgagcct tgataaattc aacctcaact ggatcctgca taaacttaaa ggctgccaac
    63901 tgccccgaac ctcctgcatg aagagtagga tggacactga caatttccag atcaaactgc
    63961 tctgccacct gacgttcaac aacgagagcc cgattgacat gctcacaacc ttgaactgct
    64021 aaatggatac ctctactacc tagaataccc aagatagtct ccactatcag ctcaccaatc
    64081 tcttgactgg attctttccc aatctgacca cctagcacct cactagaaga tagacctaaa
    64141 acaaaaagga ccccctgctt caaattggtc ttttctaaaa catcttccac tacctgacgt
    64201 gtttctcttt gaatctgtgt ctcgttcatc tctgttacct ctgttgtcac tcttctatca
    64261 taccgttttt tcttgttttt agcaagatag acaacctata aagtctgccc aattacgcat
    64321 aaaactccca gaattgactg ggagttagct agtttctatt ctatttatat atatttcaac
    64381 tttcgttcct ttttggggtc tagaatcaat cttcatctgg taattggctc caaaatgaag
    64441 tttgagccgt tgatcgacat tttgaagacc aactccccca cgtttgagtt gactttgact
    64501 actatcacca gcatcttgga agccaacgcc atcatcctca atacggatga ccaatcccga
    64561 atcctgtttc tggacagaaa gtttaatatg gccctgacct tccttttcct taatgccatg
    64621 gtaaagagca ttttctacaa ggggttgtag gaccagcttg ggtaagacta aattatcaaa
    64681 ggcaacattt tcattaattt cgtattccag cttatctcca tagcgttgtt tctggataaa
    64741 gagatactgg cggacatgat tgatttcgtc agagagacaa atcaagtcct tgccttgatt
    64801 gagcgccaag cggaaatagg ttgccaagga cttggtcacc tgcaccactc gctgactatc
    64861 atgaaattca gccatccaga tgatggtgtc caaagtgtta tagaggaaat gtggattaat
    64921 ctggctcgaa agggcttgaa gttggtactg acgggtcgtt tcttcctggc tacgaatagc
    64981 taccatcaac tgatcaatct gatccaacat agcattaaat tggcgagtta cttctctcag
    65041 ttcataggca ccaacttcct tggcacgaag attttgagca ccagaagcaa tttccaacat
    65101 ggtttctctc aaatccttca aaggagcaat ccagcgttta agactgaacc acactaagca
    65161 gagacaaaca agaagagatg tgacactggc cccaagcaag gtccacaaga gctgactccg
    65221 aacctggtct aacttttcca atgatgacac gccaagtacc gtccaatcag ttcctgcaat
    65281 cttctcttga ctgacgtagg atttgtgacc aggagtataa ccctgacctg tctcgatgta
    65341 gggtttcata gcctccattt tgctagacga actataaact gtgtgttgag gatggtagac
    65401 aaattcatgg ttttcattga taatgaaggc aaagccctgc tgccccaact ggagttgatt
    65461 gagataggct tccagagttt cataagaaat atccaaacga agcacaccaa gattggctcc
    65521 ctttgcatca acaagttctt gagtgacaga aatgacccac tgactatctg atttacgagc
    65581 tggagtcaaa acaggcatag ctccctgatg aatagccttt tggtaccaat cctcagccat
    65641 catatcagag gaagttttca tctgcacact gtcatctgta gaaatgacct gaccagattt
    65701 ggtcaccagc acaacagttt tcaagtcctt atctgacttc aagatggtca aaaacaaatc
    65761 tcggattccc tcgaccttgt cttgactggg attctcagca taggccagaa catccgtctg
    65821 ctgggtcaaa ccagtcgagg tggtttctag ttttttgata taagactgaa taaagtggct
    65881 agtctggctg atggtcgttt ggctgttgcc ctcaatggtg gcctcaatgg ctgaagaact
    65941 tgattgatag tagaaagttc caaccagagc taggagaatg agaaagacca gaaagatgga
    66001 aataaccatt ctaactaaaa gagaagaacg cttcatcggt cttctccctt cttaaactga
    66061 cgaggtgtca cacctgcaat ctgcttaaaa cgttgggtaa aatagttcat atcttcaaaa
    66121 ccaaccttct ctgcgatctc ataaatcttc agatctgtag ttaaaagcaa gagcttggct
    66181 tgtttaacac gttctctcac cagataatcc tgaaaaggca agcccaactc tttcttaatc
    66241 aaggaactca gataggtcgg actaaaacct aagtcactgg ctaaagactt taaactaaat
    66301 tggctatcag ccagatgaga ctggattttc tgggccatgt ttccttcaaa cctattagtc
    66361 aataaatctt gtaactgctc ttctttctct tccttgtcta gtttttgttt gattttcccc
    66421 aacatttcct caatatcctg acgagaaaag ggtttgagca ggtagtcgtc cacacctagt
    66481 ttgacagcag acaaggcata atcaaaatca tcgtaacctg ttaaaaagac caaatgaacc
    66541 tgaggatagg tttctcgtac cagactggcc aactggatgc catttagatg aggcatgttg
    66601 atatcggtta aaatgatatc tggcacctgc ttttggatca attcccaagc ctgccttcca
    66661 ttttcagcct gaccgatgat ttccatatcg taggctgcta cattgaccag tttagtcaaa
    66721 ccttgtctta ccagatattc atcttctacg attaagattg tgtaggtcat gctctgctcc
    66781 tttaccactt actagtatca gtatagcaaa attctcctct aactgcttag gaaagacctc
    66841 ttatactcaa taaaaatcaa aaagtaaact aggaagatag ccacaggttt ctcaaagtat
    66901 agctttgagg ttgtaaataa aactgacgaa gtcagctcaa agtatagctt tgaggttgta
//
LOCUS       DAVBED010000006        51676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBED010000006 DAVBED010000000
VERSION     DAVBED010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.006"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQ547_000375"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQ547_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQ547_000376"
     CDS             complement(604..900)
                     /locus_tag="VQ547_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542288.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ547_000377"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ547_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2542289.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQ547_000378"
     CDS             complement(4173..5399)
                     /locus_tag="VQ547_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2542290.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQ547_000379"
     CDS             complement(5442..6134)
                     /locus_tag="VQ547_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2542291.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQ547_000380"
     CDS             complement(6320..8071)
                     /locus_tag="VQ547_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542292.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQ547_000381"
     CDS             complement(8061..9806)
                     /locus_tag="VQ547_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2542293.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQ547_000382"
     CDS             complement(10012..10308)
                     /locus_tag="VQ547_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2542294.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQ547_000383"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQ547_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQ547_000384"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQ547_000384"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2542295.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQ547_000385"
     CDS             11890..12033
                     /locus_tag="VQ547_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2542296.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQ547_000386"
     CDS             12033..12272
                     /locus_tag="VQ547_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2542297.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQ547_000387"
     CDS             13151..13732
                     /locus_tag="VQ547_000387"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2542298.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQ547_000388"
     CDS             13732..14994
                     /locus_tag="VQ547_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2542299.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQ547_000389"
     CDS             complement(15081..15947)
                     /locus_tag="VQ547_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2542300.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQ547_000390"
     CDS             complement(15934..16704)
                     /locus_tag="VQ547_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2542301.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQ547_000391"
     CDS             complement(16730..17584)
                     /locus_tag="VQ547_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2542302.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQ547_000392"
     CDS             complement(17741..18145)
                     /locus_tag="VQ547_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2542303.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQ547_000393"
     CDS             complement(18215..19696)
                     /locus_tag="VQ547_000393"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2542304.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQ547_000394"
     CDS             complement(19715..20893)
                     /locus_tag="VQ547_000394"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2542305.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQ547_000395"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQ547_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2542306.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQ547_000396"
     CDS             complement(22111..23148)
                     /locus_tag="VQ547_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2542307.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQ547_000397"
     CDS             complement(23149..23502)
                     /locus_tag="VQ547_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2542308.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQ547_000398"
     CDS             complement(23746..24636)
                     /locus_tag="VQ547_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2542309.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQ547_000399"
     CDS             24769..25305
                     /locus_tag="VQ547_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2542310.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQ547_000400"
     CDS             complement(25472..26278)
                     /locus_tag="VQ547_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2542311.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQ547_000401"
     CDS             complement(26623..28143)
                     /locus_tag="VQ547_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2542312.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQ547_000402"
     CDS             complement(28136..28864)
                     /locus_tag="VQ547_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542313.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQ547_000403"
     CDS             complement(28879..29643)
                     /locus_tag="VQ547_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2542314.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQ547_000404"
     CDS             complement(29647..30090)
                     /locus_tag="VQ547_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2542315.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQ547_000405"
     CDS             complement(30772..31068)
                     /locus_tag="VQ547_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2542316.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ547_000406"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ547_000406"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2542317.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQ547_000407"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQ547_000407"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2542318.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQ547_000408"
     CDS             33679..34638
                     /locus_tag="VQ547_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542319.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQ547_000409"
     CDS             34628..35584
                     /locus_tag="VQ547_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2542320.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQ547_000410"
     CDS             35581..36333
                     /locus_tag="VQ547_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542321.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQ547_000411"
     CDS             36429..37394
                     /locus_tag="VQ547_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542322.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ547_000412"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ547_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2542323.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQ547_000413"
     CDS             complement(37861..38583)
                     /locus_tag="VQ547_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2542324.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQ547_000414"
     CDS             complement(38570..39139)
                     /locus_tag="VQ547_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2542325.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQ547_000415"
     CDS             complement(39158..39886)
                     /locus_tag="VQ547_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2542326.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ547_000416"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ547_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2542327.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQ547_000417"
     CDS             complement(40617..41078)
                     /locus_tag="VQ547_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2542328.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQ547_000418"
     CDS             complement(41075..41596)
                     /locus_tag="VQ547_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2542329.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQ547_000419"
     CDS             complement(41572..42543)
                     /locus_tag="VQ547_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2542330.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ547_000420"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ547_000420"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2542331.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQ547_000421"
     CDS             complement(43541..43789)
                     /locus_tag="VQ547_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2542332.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ547_000422"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ547_000422"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2542333.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ547_000423"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ547_000423"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2542334.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQ547_000424"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQ547_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2542335.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQ547_000425"
     CDS             complement(48629..49432)
                     /locus_tag="VQ547_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2542336.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQ547_000426"
     CDS             complement(49445..49873)
                     /locus_tag="VQ547_000426"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542337.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQ547_000427"
     CDS             complement(49882..50322)
                     /locus_tag="VQ547_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542338.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQ547_000428"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQ547_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBED010000007        48474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBED010000007 DAVBED010000000
VERSION     DAVBED010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.007"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ547_000429"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ547_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2542339.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQ547_000430"
     CDS             complement(1529..2785)
                     /locus_tag="VQ547_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2542340.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQ547_000431"
     CDS             complement(2869..3885)
                     /locus_tag="VQ547_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2542341.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQ547_000432"
     CDS             complement(3893..4411)
                     /locus_tag="VQ547_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542342.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ547_000433"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ547_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2542343.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQ547_000434"
     CDS             complement(4930..5550)
                     /locus_tag="VQ547_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542344.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQ547_000435"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQ547_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQ547_000436"
     CDS             6961..7155
                     /locus_tag="VQ547_000436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542345.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQ547_000437"
     CDS             7470..7766
                     /locus_tag="VQ547_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2542346.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQ547_000438"
     CDS             7869..9884
                     /locus_tag="VQ547_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2542347.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQ547_000439"
     CDS             9886..10518
                     /locus_tag="VQ547_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542348.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQ547_000440"
     CDS             10659..10937
                     /locus_tag="VQ547_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2542349.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ547_000441"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ547_000441"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2542350.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ547_000442"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ547_000442"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2542351.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ547_000443"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ547_000443"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2542352.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQ547_000444"
     tRNA            19707..19777
                     /locus_tag="VQ547_000444"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQ547_000445"
     CDS             complement(19975..21306)
                     /locus_tag="VQ547_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2542353.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ547_000446"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ547_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2542354.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQ547_000447"
     CDS             complement(22460..22648)
                     /locus_tag="VQ547_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2542355.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ547_000448"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ547_000448"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2542356.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQ547_000449"
     CDS             complement(23948..24178)
                     /locus_tag="VQ547_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2542357.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQ547_000450"
     CDS             complement(24236..25273)
                     /locus_tag="VQ547_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2542358.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ547_000451"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ547_000451"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2542359.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ547_000452"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ547_000452"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2542360.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQ547_000453"
     CDS             complement(26339..27331)
                     /locus_tag="VQ547_000453"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2542361.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQ547_000454"
     CDS             complement(27443..28126)
                     /locus_tag="VQ547_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2542362.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQ547_000455"
     CDS             complement(28182..28922)
                     /locus_tag="VQ547_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2542363.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQ547_000456"
     CDS             28956..29234
                     /locus_tag="VQ547_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2542364.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQ547_000457"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQ547_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2542365.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ547_000458"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ547_000458"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2542366.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVEKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQ547_000459"
     CDS             complement(31233..32483)
                     /locus_tag="VQ547_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2542367.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ547_000460"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ547_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2542368.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQ547_000461"
     CDS             complement(33644..34585)
                     /locus_tag="VQ547_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2542369.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQ547_000462"
     CDS             complement(34575..35831)
                     /locus_tag="VQ547_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2542370.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQ547_000463"
     CDS             complement(35833..36495)
                     /locus_tag="VQ547_000463"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2542371.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQ547_000464"
     CDS             complement(36458..37114)
                     /locus_tag="VQ547_000464"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2542372.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ547_000465"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ547_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2542373.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQ547_000466"
     CDS             complement(38596..39369)
                     /locus_tag="VQ547_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2542374.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ547_000467"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ547_000467"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2542375.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQ547_000468"
     CDS             complement(41182..41400)
                     /locus_tag="VQ547_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542376.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQ547_000469"
     CDS             complement(41468..42109)
                     /locus_tag="VQ547_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542377.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQ547_000470"
     CDS             complement(42111..44141)
                     /locus_tag="VQ547_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2542378.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQ547_000471"
     CDS             complement(44410..45309)
                     /locus_tag="VQ547_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542379.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ547_000472"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ547_000472"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2542380.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQ547_000473"
     CDS             complement(45941..46714)
                     /locus_tag="VQ547_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2542381.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQ547_000474"
     CDS             complement(47019..47912)
                     /locus_tag="VQ547_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2542382.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ547_000475"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ547_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2542383.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13990 a        10915 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttctcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccat gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBED010000008        46213 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBED010000008 DAVBED010000000
VERSION     DAVBED010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.008"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQ547_000476"
     CDS             <1..128
                     /locus_tag="VQ547_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2542384.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQ547_000477"
     CDS             complement(257..460)
                     /locus_tag="VQ547_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542385.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQ547_000478"
     CDS             complement(453..1535)
                     /locus_tag="VQ547_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2542386.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQ547_000479"
     CDS             complement(1661..2443)
                     /locus_tag="VQ547_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2542387.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQ547_000480"
     CDS             complement(2443..3786)
                     /locus_tag="VQ547_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2542388.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQ547_000481"
     CDS             complement(3885..5201)
                     /locus_tag="VQ547_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2542389.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQ547_000482"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQ547_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQ547_000483"
     CDS             6814..8388
                     /locus_tag="VQ547_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2542390.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8652..9440
                     /gene="codY"
                     /locus_tag="VQ547_000484"
     CDS             8652..9440
                     /gene="codY"
                     /locus_tag="VQ547_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2542391.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9440..10015
                     /locus_tag="VQ547_000485"
     CDS             9440..10015
                     /locus_tag="VQ547_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2542392.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10097..10182
                     /locus_tag="VQ547_000486"
     tRNA            10097..10182
                     /locus_tag="VQ547_000486"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10131..10133,aa:Leu,seq:aag)
     gene            10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ547_000487"
     CDS             10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ547_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2542393.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12096..12854
                     /locus_tag="VQ547_000488"
     CDS             12096..12854
                     /locus_tag="VQ547_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2542394.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12941..13453
                     /locus_tag="VQ547_000489"
     CDS             12941..13453
                     /locus_tag="VQ547_000489"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2542395.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13635..14579
                     /locus_tag="VQ547_000490"
     CDS             13635..14579
                     /locus_tag="VQ547_000490"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2542396.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14588..15265
                     /locus_tag="VQ547_000491"
     CDS             14588..15265
                     /locus_tag="VQ547_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2542397.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15363..16121
                     /locus_tag="VQ547_000492"
     CDS             15363..16121
                     /locus_tag="VQ547_000492"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2542398.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16159..17664
                     /gene="lytC"
                     /locus_tag="VQ547_000493"
     CDS             16159..17664
                     /gene="lytC"
                     /locus_tag="VQ547_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2542399.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18160..18678
                     /locus_tag="VQ547_000494"
     CDS             18160..18678
                     /locus_tag="VQ547_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2542400.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18808..19314
                     /locus_tag="VQ547_000495"
     CDS             18808..19314
                     /locus_tag="VQ547_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2542401.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19314..19484
                     /locus_tag="VQ547_000496"
     CDS             19314..19484
                     /locus_tag="VQ547_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542402.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19516..20748
                     /gene="clpX"
                     /locus_tag="VQ547_000497"
     CDS             19516..20748
                     /gene="clpX"
                     /locus_tag="VQ547_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2542403.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20757..21344
                     /locus_tag="VQ547_000498"
     CDS             20757..21344
                     /locus_tag="VQ547_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2542404.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21355..21735
                     /locus_tag="VQ547_000499"
     CDS             21355..21735
                     /locus_tag="VQ547_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2542405.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ547_000500"
     CDS             21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ547_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2542406.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22674..23651
                     /locus_tag="VQ547_000501"
     CDS             22674..23651
                     /locus_tag="VQ547_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2542407.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23648..24559
                     /gene="whiA"
                     /locus_tag="VQ547_000502"
     CDS             23648..24559
                     /gene="whiA"
                     /locus_tag="VQ547_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2542408.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24593..25561)
                     /locus_tag="VQ547_000503"
     CDS             complement(24593..25561)
                     /locus_tag="VQ547_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2542409.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25697..26554
                     /locus_tag="VQ547_000504"
     CDS             25697..26554
                     /locus_tag="VQ547_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2542410.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26541..27320
                     /locus_tag="VQ547_000505"
     CDS             26541..27320
                     /locus_tag="VQ547_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2542411.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27344..28696
                     /locus_tag="VQ547_000506"
     CDS             27344..28696
                     /locus_tag="VQ547_000506"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2542412.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28770..29144
                     /locus_tag="VQ547_000507"
     CDS             28770..29144
                     /locus_tag="VQ547_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2542413.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29146..29994
                     /locus_tag="VQ547_000508"
     CDS             29146..29994
                     /locus_tag="VQ547_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2542414.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30271..31038
                     /locus_tag="VQ547_000509"
     CDS             30271..31038
                     /locus_tag="VQ547_000509"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2542415.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31050..32234
                     /locus_tag="VQ547_000510"
     CDS             31050..32234
                     /locus_tag="VQ547_000510"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2542416.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32231..34102
                     /locus_tag="VQ547_000511"
     CDS             32231..34102
                     /locus_tag="VQ547_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2542417.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ547_000512"
     CDS             complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ547_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2542418.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35733..38429
                     /locus_tag="VQ547_000513"
     CDS             35733..38429
                     /locus_tag="VQ547_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2542419.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38442..39233
                     /gene="yghU"
                     /locus_tag="VQ547_000514"
     CDS             38442..39233
                     /gene="yghU"
                     /locus_tag="VQ547_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2542420.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39349..39759
                     /locus_tag="VQ547_000515"
     CDS             39349..39759
                     /locus_tag="VQ547_000515"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2542421.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39771..41366
                     /locus_tag="VQ547_000516"
     CDS             39771..41366
                     /locus_tag="VQ547_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542422.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41533..41697
                     /locus_tag="VQ547_000517"
     CDS             41533..41697
                     /locus_tag="VQ547_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2542423.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ547_000518"
     CDS             41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ547_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2542424.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKVAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42555..44039)
                     /locus_tag="VQ547_000519"
     CDS             complement(42555..44039)
                     /locus_tag="VQ547_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2542425.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44255..>46213
                     /locus_tag="VQ547_000520"
     CDS             44255..>46213
                     /locus_tag="VQ547_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2542426.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDR"
BASE COUNT        13770 a         8551 c        10459 g        13433 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa gtcaataagg
     8581 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
     8641 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
     8701 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
     8761 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
     8821 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
     8881 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
     8941 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
     9001 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
     9061 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
     9121 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
     9181 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
     9241 aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt atcggaatca
     9301 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
     9361 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
     9421 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
     9481 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
     9541 cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
     9601 tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc ataatctgat
     9661 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
     9721 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
     9781 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
     9841 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
     9901 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
     9961 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
    10021 ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa gttgatatac
    10081 tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact aaggatcctg
    10141 tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa gagttagcta
    10201 aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta gtggagaatc
    10261 agcgaaaata tgggaaaact gttccttgtt tctgcttttg tcatagaaga ataataaaga
    10321 ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca cagaactttt
    10381 ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatctata atataattat
    10441 caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat ttacaaaaaa
    10501 tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacatcaa agataaagaa
    10561 tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg tatgattgct
    10621 ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt caacgacgta
    10681 gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta cccacacatg
    10741 actgtttatg acaacatggc tttcggtttg aaattgcgta aatacagcaa agaagacatt
    10801 aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt ggaacgtaaa
    10861 ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc gattgtccgt
    10921 gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa acttcgtgta
    10981 tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac tatctatgta
    11041 actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat gtcagctact
    11101 aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac tcctcaagaa
    11161 gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc agctatgaac
    11221 ttcatcaacg tgaaattggt tggtagcgaa attgtttctg acggtttccg tttgaaagtg
    11281 ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga attgatcttt
    11341 ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt cccagactgt
    11401 gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca cctttactgc
    11461 caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt gcaaacaggt
    11521 gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt agaaactgaa
    11581 aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata tctctttatc
    11641 aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt
    11701 tgctagggaa gtcatattat gcatctatat tgtgatgctc tttaatactc ttcgaaaatc
    11761 tcttcaaacc acgtcaacgt cgccttgccg tacgtatgat tactgatttc gtcagtttta
    11821 tctgcaacct caaagatgta ctttgagcag cttacggcta gtttcctagt ttgctctttg
    11881 atttccattg agtattattt gtgggtacca tctacaagtg aagctatatg cgtaaactac
    11941 gtgagcaatt gaattcgaac tagagaggta ataataaatt tatgctatag ttatggtgac
    12001 ttgtatgctt ttgattctag tttatcaaat aatagattag aattgtcaga taatatcatt
    12061 ttgtgttata atgaagaaaa aacagaggtg ttcaaatgtc agaagcaggt cataagtttt
    12121 tagcaaaatt ggggaaaaaa cgcttacgtc caggtggaaa gcgtgctaca gattggttaa
    12181 ttgcagaagg aggattgtca aaagaaaaga gaatactaga ggttgcgtgt aataggggaa
    12241 ctacagcaat tgagttggca cagcgttttg gttgcaagat aactgctgtt gatatggatg
    12301 ctcaagcttt agaagtggct aaaaaatctg ctggaacggc aggtgttgct catttaatca
    12361 gttttgaaag agcaaatgca atgaaacttc cttatcaaga tgctagtttt gatattgtta
    12421 taaatgaagc tatgctgact atgcaagccg atcaagctaa gaaaaaatgt gtaatggaat
    12481 atctaagggt attaaaacct ggaggtcttc ttttgacaca tgatgtgctt cttaaggaag
    12541 ctaaagagtc tatcagacag gaattatcac aagcaattca tgtaaatgta ggtcctttaa
    12601 ctcaagatgg ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg aaagtattga
    12661 ctggtgaaat gacattaatg aaattatcgg gtatgattta tgacgaaggt tggctaggaa
    12721 ctttgaaaat ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt ttaactatgt
    12781 ataaaatgtt tgctaagaat aaacagaaat tgggctttat tgcgatggct agttataaat
    12841 cgtcaaaacg ttagataatt attgaagtta acttttcctt ttttctttct taaaaaatat
    12901 gctataatag agagtgaaaa actttgaaag aaagaaaaag atgaatttaa aagattacat
    12961 tgcaacaatt gaaaattatc caaaggaagg cattaccttc cgtgatatta gtcctttgat
    13021 ggctgatgga aatgcttata gctacgctgt tcgtgaaatc gttcagtatg ctactgacaa
    13081 gaaagtcgac atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt gtccagttgc
    13141 ctttgagttg ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc cacgcgaagt
    13201 tatttctgct gactatgaaa aagagtacgg tgtcgatacc ttgactatgc acgcggatgc
    13261 cattaagcca ggtcaacgtg ttcttattgt agatgacctt ttggcgacag gtggaactgt
    13321 taaggcaact atcgagatga ttgaaaaact tggtggtgtt atggcaggtt gtgccttcct
    13381 tgttgaattg gatgaattga acggccgtga aaaaatcggt gactacgact acaaagttct
    13441 tatgcattat taatgaaaac agtccctagg gctgttttct ctacactagg atataaaaat
    13501 agactataac tagttagaga aaaactataa ttgaaaacta tatcttcttg cagtataata
    13561 aaaggactaa gtgtttgaga tttgtcttca aacacatgca attattcctg agagagtaca
    13621 gttaggagag ggttatgccg attcgaattg ataaaaaatt gccagctgtt gagattttac
    13681 ggacagagaa tatctttgtc atggatgatc aacgtgctgc ccaccaagat atccgtcctt
    13741 tgaagatttt aattttaaat ctcatgccac agaaaatggt cacagagacc cagttgttgc
    13801 gtcacttggc taatacaccc ctacaactgg atattgattt tctctatatg gagagccacc
    13861 gttctaaaac aactcgttca gagcacatgg agaccttcta taaaactttt cctgaagtca
    13921 aggatgagta ttttgatggg atgatcatca cgggtgctcc agttgagcat ttaccatttg
    13981 aggaagtgga ctattgggag gaatttaggc agatgcttga gtggtctaag acacatgtct
    14041 attcgaccct tcatatctgt tggggggctc aggctgggct ttatctgcgc tatggtgtag
    14101 aaaaatacca gatggacagt aagctatcag gtatttatcc tcaggacacc ctaaaagagg
    14161 gtcaccttct atttagaggc tttgatgata gctatgtatc ccctcattca cggcacacgg
    14221 agatttctaa ggaagaggtc ttaaacaaga ccaatctcga gattttatca gaaggacctc
    14281 aggttggggt ttctattttg gccagtcgtg atttacgaga aatttatagt tttggtcatt
    14341 tggagtatga ccgtgatacc ttggcaaaag agtattttcg agatcgtgat gcaggtttcg
    14401 acccacatat tccagaaaat tactttaaag atgatgatgt taatcaggta ccttgtcttt
    14461 gttggtcttc atctgcagcc ctctttttca gtaattgggt aaaccatgcg gtctatcagg
    14521 agacgccttt tgattggaga aagatagaag atgatgcatc tgcatatggg tatttataag
    14581 aggaattatg acatatttag acgcttttaa atcaggtacc ttggttttac cgagtgccct
    14641 gctcttgcat tttaaggaac tctttccttc tagcgacgat tttctggttt ggcaattttt
    14701 ctatttgcaa aatacgacag gcttagaaga aatgtcgcca agccagattg ctgaaaggat
    14761 tggcaaggaa atttcggatg tcaaccagtc catttctaat ctgacggaaa ggggactgct
    14821 ccagtatcgt actatcgaat taaatggcga aattgaattg ctctttgatg ctagtttggc
    14881 cttggaacgt ttggatgacc tgtttggagc agttcgttca agttcagacc agctaacacc
    14941 tcaaaaccag ctcaaggatt tggtggaaac cttccagcag gagttgggac gattgttgac
    15001 gccttttgag attgaggatt tgaccaagac actaaaggaa gatggaacca gtgctgactt
    15061 gattaaggag gctcttcgtg aagctgtttt gaatggaaaa ccaaactgga agtacattca
    15121 ggcgattttg agaaactggc gccatgaagg aatcaagagt gtggctcaaa ttgaggccaa
    15181 gagagcagaa agagaagcaa gcaatcctca gttgacacag gtatctgcag atttcagaaa
    15241 tgccatggat ctctggaagg attaatccat gcaagtaggc ttgaaatccg agtaagattt
    15301 gcaagctgtg tataattgtg atagaataaa tagaaaataa attgaaaaaa gaggtatgtg
    15361 aaatgtcacg taaaccattt atcgctggta actggaaaat gaacaaaaat ccagaagaag
    15421 ctaaagcatt cgttgaagca gttgcatcaa aacttccttc atcagatctt gttgaagcag
    15481 gtatcgctgc tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa ggctcaaacc
    15541 ttaaagttgc tgctcaaaac tgctactttg aaaatgcagg tgctttcact ggtgaaacta
    15601 gcccacaagt tttgaaagaa atcggtactg attacgttgt tatcggtcac tcagaacgcc
    15661 gtgactactt ccatgaaact gacgaagata tcaacaaaaa agcaaaagca atctttgcga
    15721 acggtatgct tccaatcatc tgttgtggtg aatcacttga aacttacgaa gctggtaaag
    15781 ctgctgaatt cgtaggtgct caagtatctg ctgcattggc tggattgact gctgaacaag
    15841 ttgctgcctc agttatcgct tatgagccaa tctgggctat cggtactggt aaatcagctt
    15901 cacaagacga tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct gctgactttg
    15961 gtcaagaagt cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa cctgaaaatg
    16021 ttgcttcata catggcttgc ccagacgttg acggtgccct tgtaggtggt gcgtcacttg
    16081 aagctgaaag cttcttggct ttgcttgact ttgtaaaata atcagtaagt agcaaaagct
    16141 aggtggaaca gcattcagat gtctgttaca ttttttatag gagaggaaag attgaaaaca
    16201 aaaattggat tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt cgctgcaaat
    16261 gaaactgaag tagcaaaaac ttcgcaggat acaacgacag cttcaagtag ttcagagcaa
    16321 aatcagtctt ctaataaaac gcaaacgagc acagaagtac agactaatgc tgctgcccac
    16381 tgggatgggg attattatgt aaaggatgat ggctctaaag ctcaaagtga atggattttt
    16441 gacaactact ataaggcctg gttttatatt aattcagatg gtcgttactc gcagaatgaa
    16501 tggcatggaa attactacct gaaatcaggt ggatatatgg cccaaaacga gtggatctat
    16561 gacagtaatt acaagagttg gttttatctc aagtcagatg gggcttatgc tcatcaagaa
    16621 tggcaattga ttggaaataa gtggtactac ttcaagaagt ggggttacat ggctaaaagc
    16681 caatggcaag gaagttattt cttgaatggt caaggagcta tgatgcaaaa tgaatggctc
    16741 tatgatccag cctattctgc ttatttttat ctaaaatccg atggaactta tgctaaccaa
    16801 gagtggcaaa aagtgggcgg aaaatggtac tatttcaaga agtggggcta tatggctcgg
    16861 aatgagtggc aaggcaacta ctatttgact ggaagtggtg ctatggcgac tgacgaagtg
    16921 attatggatg gtgctcgcta tatctttgcg gcctctggtg agctcaaaga aaagaaagat
    16981 ttgaatgtcg gctgggttca cagagatggt aaacgctatt tctttaataa tagagaagaa
    17041 caagtgggaa ccgaacatgc taagaaaatc attgatatta gtgagcacaa tggtcgtatc
    17101 aatgattgga aaaaggttat tgatgagaac gaggtggatg gtgtcattgt tcgtctaggt
    17161 tatagcggta aagaagacaa ggaattggcg cataacatta aggagttaaa ccgtctggga
    17221 attccttatg gtgtctatct ctatacctat gctgaaaatg agaccgatgc tgagagtgac
    17281 gctaaacaga ccattgaact tataaagaaa tacaatatga acctgtctta ccctatctat
    17341 tatgatgttg agaattggga atatgtaaat aagagcaaga gagctccaag tgatacaggc
    17401 acttgggtta aaatcatcaa caagtacatg gacacgatga agcaggcggg ttatcaaaat
    17461 gtgtatgtct atagctatcg tagtttatta cagacgcgtt taaaacaccc agatatttta
    17521 aaacatgtaa actgggtagc ggcctatacg aatgctttag aatgggaaaa ccctcattat
    17581 tcaggaaaaa aaggttggca atatacctct tctgaataca tgaaaggaat ccaagggcgc
    17641 gtagatgtca gcgtttggta ttaagcgatg atttgaaaga gggatgtgat agtagcaccc
    17701 tctttttctt tgttttatga tagttcatcc tcgagtaaat tcaagttctt gctcggaaat
    17761 gaagcttata tagtagattg aatatagaca aataccttgt gattggtaaa acattttaga
    17821 aattcattta cctttcctaa tcgacttggt ttcatcttat ttcaatctat tatagtattg
    17881 gggaatttct tcaaaccaca tcagcttggt cagttctacc tgcgacctca aaacttgtgc
    17941 tttggtcaag ctgggtttag tttcctagtt tgctgatgga tttccattga ctataagcat
    18001 ccaaccctct ttttgtcttc taaagaattc ttaaattatc agtctattgc aacttttctc
    18061 atataagttc tttgtcttgc tattggtttt ccttagtagt atactaaggt agtaatcatt
    18121 aagaagtggt tacaaaaaat aatgaatgag gtaaagaaaa tggtagaatt gaaaaaagaa
    18181 gcagtaaaag acgtaacatc attgacaaaa gcagcgccag tagcattggc aaaaacaaag
    18241 gaagtcttga accaagctgt tgctgatttg tatgtagctc acgttgcttt gcaccaagtg
    18301 cactggtata tgcatggtcg tggtttcctt gtatggcatc caaaaatgga tgagtacatg
    18361 gaagctcttg acggtcaatt ggatgaaatc agtgaacgct tgattacact cggtggaagc
    18421 ccattctcta cattgacaga gttccttcaa aatagtgaaa tcgaagaaga agctggtgaa
    18481 taccgtaatg ttgaagaaag cttggaacgt gttcttgtta tctaccgtta cttgtcagaa
    18541 cttttccaaa aaggtttgga tgtcactgat gaagaaggtg acgatgtgac aaacggtatc
    18601 tttgcaggcg ctaaaactga aacagataaa acaatttgga tgcttgcagc cgaacttgga
    18661 caagcacctg gtttgtaaga aataaggaaa catagataaa tctgtaggaa atttcttaca
    18721 gattttttct attttgtaag ctattccaaa ccagtctttt tttgagtttt ttgataaaat
    18781 agtactatca gtgaaaagga tggaagcatg actaagaaaa tcgtagctat ttgggcccag
    18841 gatgaagagg gtgtgattgg taaggaaaat cgtctgcctt ggcatttgcc agcagaattg
    18901 cagcacttta aagaaacaac tctgaatcat gctatcttga tggggcgtgt gacctttgat
    18961 gggatggggc gtcgcttgct tccaaaacgg gaaaccttga ttttgacgcg taatccggaa
    19021 gaaaagatag atggggttgc tacttttcag gacgtccagt ctgttcttga ctggtatcag
    19081 gctcaagaaa agaatctcta cattatcggt gggaagcaaa tttttcaggc ttttgaacct
    19141 taccttgatg aagtgattgt cactcacatt catgctcggg tggaaggaga tacctatttc
    19201 cctgaagaac ttgacttgtc tctttttgag acagtttcaa gcaaatttta cgccaaagat
    19261 gagaagaatc cttatgattt taccatccaa taccgcaaga gaaaggaagt ctaatggaac
    19321 ggagtttatt tggtctattc acggcttttc tgtgtttcat ctgctttctg gcaggagcac
    19381 aagcttttcg taaaaagcgt tacgggcttt ctatcctcct ttggttaaat gcctttacca
    19441 atctggtcaa tagtattcat gctttttaca tgaccttatt ttagatagaa tgacagtata
    19501 gaatggaagg aaatcatgtc tacaaataga aaaaatgata tgatggttta ttgctcattt
    19561 tgtggcaaaa accaagaaga agtacaaaaa ataattgctg gcaacaatgc ttttatttgt
    19621 aatgaatgcg tggagttagc tcaggaaatc attcgagaag aattggttga ggaagtcttg
    19681 gcagacttgt ctgaggtgcc aaaaccaatt gaactcctcc atatcttgaa ccactatgta
    19741 attggtcaag atcgtgccaa gcgtgccttg gcagtggcgg tttataacca ctacaaacgc
    19801 atcaatttcc acgatacacg cgaagagtca gaagatgtgg atttgcagaa gtcaaacatt
    19861 ttgatgattg gcccaactgg ttcagggaaa actttccttg cccagacctt ggctaagagc
    19921 ttgaatgtac cttttgctat tgcggatgcg acagctctga cggaggctgg ttatgtgggt
    19981 gaggatgtgg aaaatatact cctcaaactc ttgcaggttg ctgactttaa catcgaacgt
    20041 gcagagcgtg gcattatcta tgtggatgaa attgacaaga ttgccaagaa gagtgagaat
    20101 gtgtctatca cacgtgatgt ttctggtgaa ggggtgcaac aagcccttct caagattatt
    20161 gagggaactg ttgctagcgt accgcctcaa ggtggacgca aacatccaca acaagagatg
    20221 attcaagtgg atacaaaaaa tatcctcttc atcgtgggtg gtgcttttga tggtattgaa
    20281 gaaattgtca aacaacgtct gggtgaaaaa gtcatcggat ttggtcaaaa caataaggcg
    20341 attgacgaaa acagctcata catgcaagaa atcatcgctg aagacattca aaaatttggt
    20401 attatccctg agttgattgg acgcttgcct gtttttgcgg ctcttgagca attgaccgtt
    20461 gatgacttgg ttcgcatctt gaaagagcca agaaatgcct tggtgaaaca ataccaaacc
    20521 ttgctttctt atgatgatgt tgagttggaa tttgacgacg aagcccttca agagattgct
    20581 aataaagcaa tcgaacggaa gacaggggcg cgtggacttc gctccatcat cgaagaaacc
    20641 atgctagatg ttatgtttga ggtgccgagt caggaaaatg tgaaattggt tcgtatcact
    20701 aaagaaactg tcgatggaac ggataaaccg atcctagaaa cagcctagag gtgactatgg
    20761 aacttaatac acacaatgct gaaatcttgc tcagtgcagc taataagtcc cactatccgc
    20821 aggatgaact gccagagatt gccctagcag ggcgttcaaa tgttggtaaa tccagcttta
    20881 tcaacactat gttgaaccgt aagaatctcg cccgtacatc aggaaaacct ggtaaaaccc
    20941 agctcctgaa cttttttaac attgatgaca agatgcgctt tgtggatgtg cctggttatg
    21001 gctatgctcg tgtttctaaa aaggaacgtg aaaagtgggg gtgcatgatt gaggagtact
    21061 taacgactcg ggaaaatctc cgtgcggttg tcagtctagt tgaccttcgt catgacccgt
    21121 cagcagatga tgtgcagatg tacgaatttc tcaagtatta tgagattcca gtcatcattg
    21181 tggcgaccaa ggcggacaag attcctcgtg gtaaatggaa caagcatgaa tcagcaatca
    21241 aaaagaaatt aaactttgac ccaagtgacg atttcatcct cttttcatct gtcagcaagg
    21301 cagggatgga tgaggcttgg gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca
    21361 aaaacaattc atacagataa ggccccaaag gctatcggac cctatgttca aggaaaaatc
    21421 gttggcaacc ttttgtttgc tagcggtcaa gttcccctat cccctgaaac tggggaaatt
    21481 gtaggagaga atatccaaga acagacagag caagtcttga aaaacatcgg tgctattttg
    21541 gcagaagcag gaacagactt tgaccatgtt gtcaaaacaa cttgcttctt gagcgatatg
    21601 aacgactttg ttccttttaa tgaggtttac caaacggcct tcaaagagga attcccagct
    21661 cgttcagctg tggaggtagc tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc
    21721 gcagagattg gataagctag ttgaagtttg gtgttgccaa acttcttttg atataaggag
    21781 aaaaagatga caaagaaaca acttcacttg gtgattgtga cagggatgag tggcgcaggg
    21841 aaaactgtag ccattcagtc cttcgaggat ctaggttatt tcaccattga taatatgccg
    21901 ccagctctct tgcctaagtt tttgcagctg gttgaaatta aggaagataa tcctaagttg
    21961 gctttggtag tggatatgcg tagccgttct ttcttttcag agattcaagc tgttttggat
    22021 gagttggaaa atcaagatgg tttggatttc aaaatcctct ttttggatgc ggctgataag
    22081 gaattggtcg ctcgttacaa ggaaaccaga cggagtcacc cactagcagc agacggtcgt
    22141 attttagatg gaatcaagtt ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa
    22201 aatgtggtgg atacgactga actcactcca cgtgaactgc gcaaaaccct tgcagagcag
    22261 ttttcagacc aagaacaagc ccagtctttc cgtatcgaag tcatgtcttt cggatttaag
    22321 tatggaatcc cgattgatgc ggacttggtc tttgatgtcc gtttcttgcc aaatccctat
    22381 tatctaccag aactgagaaa ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg
    22441 aaccatcctg agtcagaaga cttttatcaa catttattgg ccttgattga gccgattctg
    22501 ccaagttacc aaaaggaagg taagtccgtt ttgaccattg ctatgggatg tacgggtgga
    22561 caacaccgta gtgtggcatt tgctaaacgc ttggcgcagg acttatccaa gaattggtct
    22621 gttaatgaag ggcatcgcga caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa
    22681 aaccaaagat aacggtgatt ggtggaggga ctggaattcc cgtcattcta aaaagtctgc
    22741 gggaaaaaga tgtggaaatc gcagctatcg tgacggtggc agatgatggt ggttcttcag
    22801 gtgaactccg aaaaaatatg caacagttga caccgccagg tgatcttcgt aatgtccttg
    22861 tggccatgtc ggatatgcct aagttttatg agaaggtctt tcagtatcgg ttctctgagg
    22921 atgccggagc ctttgctggc catccattgg gaaatctcat cattgctggc ttgtcagaaa
    22981 tgcagggttc aacctataat gccatgcagt tattgagcaa atttttccat acaacaggga
    23041 aaatttatcc ttccagtgac catcctttga cccttcatgc agtctttcag gatgggacag
    23101 aagtggctgg agagagtcat attgtagacc atcgaggcat aattgacaat gtctatgtga
    23161 ccaatgccct aaacgatgat acgcctctgg ccagccgtcg agtagtgcag accatccttg
    23221 aaagtgacat gattgtccta gggccaggtt ccctctttac ctctattttg cccaatatcg
    23281 tgattaagga aattgggcgg gctcttttgg aaactaaggc agaaattgcc tatgtctgca
    23341 atatcatgac ccaacgtggg gagacggaac actttacaga tagcgaccac gtggaagtct
    23401 tgcatcgtca ccttggtcgc ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc
    23461 ctcaggaata catgaattcc aaccgttttg atgaatactt ggtgcaagtg gaacacgatt
    23521 ttgtaggtct ttgtaagcaa gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa
    23581 atggcggtgc cttccacgat ggagatttga ttgtggacga gttgatgcgc attatacagg
    23641 tgaaaaaatg agtttcacag tagcagtaaa agaagaaatc ctgggccaac accatctgag
    23701 ccggcatgaa ttatctgcca ttatcaaaat gtctggtagc atcggtctct cgacttcggg
    23761 cttgactttg tcagttgtga cagaaaatgc caaactggcc cgtcacctct atgagtcctt
    23821 tctccatttc tatgaaatca aatctgaaat tcgtcaccac caacggagca atcttcgcaa
    23881 gaatcgcgtc tataccgttt ttacagatga aaaggtgcag gatttgttaa gtgatttgca
    23941 cttggcagac tctttctttg gcctggaaac aggtattgat gaggcgattt tatcggatga
    24001 ggaagcaggt cgtgcctatc tctgtggcgc tttcttggca aatgggagca ttcgtgaccc
    24061 tgagtcaggc aagtaccagt tggaaatcag ttctgtttat ctggaccacg cgcaaggaat
    24121 tgcctccctt ctccaacagt ttttactgga tgccaaggtg cttgagcgca agaagggggc
    24181 tgtgacctat ctccagcgag cagaagacat tatggacttc ttgatagtaa tcggagccat
    24241 gcaggcacgt gatgattttg agcgggttaa gattttgcga gaaacccgta acgacctcaa
    24301 tcgggctaat aatgccgaga cagctaatat cgctcggaca gtttctgcca gcatgaagac
    24361 cattaacaat atcagtaaaa taaaagatat catgggctta gaaaatttgc cagtagattt
    24421 gcaggaagtg gcgcaactga ggattcagca cccagactac tctatccagc agttagcaga
    24481 tagtctcagc acccctctga ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa
    24541 gatagcggat gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac
    24601 tggtagagtg ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga
    24661 cagcagttgg agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc
    24721 agcagtcacc gatagcatag atacctgctt ggctggattc ctgtttgctg ttgacgataa
    24781 tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac
    24841 catagttgac aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg
    24901 tgatttcaag tttatcaagt gtttttccat ttccaaggag ttggctaggg gcgaatggtg
    24961 tcttgatggt tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat
    25021 tatctctgcg gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gtccaatcca
    25081 cagccgagtc tcccccacca agaatcgtca cttttttacc agcgtattgc tgaatgttag
    25141 aaacgtggta gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt
    25201 tgaaggcacc gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag
    25261 ttgtgatggc aaattcttct tcttgtttgt caatctcaag aaccgtttca ttgagatgaa
    25321 taggggtatc aaatccattt agctgttcaa tcaagcggtt agtcaactct tctccagtca
    25381 ggtttgggaa gcctggtacg tctaggattt ccttttcagg gtagagaata gcaggttgtc
    25441 cacctagctg gggaagagag tcgatgattt gaaccttggc ttggcgtagg tgggcataaa
    25501 aggctgcaaa aagcccgaca ggaccaccac ccacaatggt aatatcatag agttgagaca
    25561 tagtttctcc tttgtttttt ctagtcagtt tattttatca tatttttgtt caatgtaaaa
    25621 tggactagga tagggaaaaa aatgccagaa aatggtataa taggacgaaa gtgttttgat
    25681 agggaggata tcagggatga attttcaaca attatccaat ttgcaatatt ggaccagttt
    25741 gtttgcaagt ccatggacga tagctatcaa tctgattgat attttgattg ttgcttatat
    25801 tttataccat tttacaaaag ctattgcagg aaccaagatt atgattttgg tacgtggagt
    25861 tttggtattt attttagctc aaatccttgc aaatatgatt ggtttgacta cgatttcttg
    25921 gttaatcaat caaattatta cttatggggt tattgcggcg gttgttatct tctctccaga
    25981 gattcggact ggtttggaac gtttgggaag agcgacagat ttcttttcca atgcccctat
    26041 tagtgctgag gaacagatga ttcgtgcctt tgttaagtct gttgaataca tgagtcctcg
    26101 taaaatcggg gccttggttg ctattcagcg tgtacgtacc ttgcaggagt atatttcgac
    26161 aggaattccc ttggatgcta agatttctgc agaacttctc attaacattt ttattcccaa
    26221 cactccccta catgacggtg cggtgattat caaagaagaa cgtatcgctg tgacgtctgc
    26281 ctatctgccc ttgacaaaaa acacagggat ttccaaggaa tttgggacca gacaccgggc
    26341 ggctatcggt ttatcagaag tctcagatgc cttgactttt gtcgtatcag aggaaacggg
    26401 aggaatttcg ataacctata atggaaggtt taagcacaac ctaacacttg atgaatttga
    26461 aacagaatta cgtgaaatct tacttccaaa agaggaagta ggtcttagtt ttaaagaacg
    26521 attgctagga ggatggaaac atgaaaaaaa atagtttata tatcatatcc tcactctttt
    26581 ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt tcaaaacagt accagtgcta
    26641 ggcaggtaaa aacggaaacc tatactaata cagtaacaaa tgtccctatt gacatacgct
    26701 ataatagtga taagtatttt attagcggtt ttgcttcaga agtatcagtg gtcttgactg
    26761 gtgcaaatcg cctatcgcta gctagtgaaa tgcaagaaag tacacgtaaa ttcaaggtta
    26821 ctgctgacct aacagatgcc ggtgttggaa caattgaagt tcctttgagc attgaagatt
    26881 tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat tacagtcaag attggtaaga
    26941 aggctcagaa ggataaggta aagattgtac cagagattga ccctagtcaa attgatagtc
    27001 gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt gtcgattacg agtgaccaag
    27061 agacattgga tagaattgat aagattatcg ctgtcttgcc aactagcgaa cgcataacag
    27121 gtaattacag tggttcagta cctttgcagg caatcgaccg caatggtgtt gtcttaccgg
    27181 cagttatcac tccgtttgat acaataatga aggtgactac aaaaccagta gcaccaagtt
    27241 caagcacatc aaattcaagt acaagcagtt catcggagac atcttcgtca acgaaagcaa
    27301 ctagttcaaa aacgaattaa aaatagaaaa ggattttata acaatgggta aatattttgg
    27361 gactgatgga gtccgtggag aagctaacct agaactaaca ccagaattag cctttaaact
    27421 aggacgtttt ggaggctatg ttcttagtca acatgaaacg gaagcgccga aagtctttgt
    27481 aggacgtgac acacgtattt caggggaaat gctagaatcg gccttggtgg caggtctcct
    27541 ttcagtaggg attcacgtat acaaacttgg tgtccttgca acaccagcag tagcttactt
    27601 ggttgaaact gaaggagcaa gtgctggtgt catgatttct gctagccaca atccagctct
    27661 tgataacgga atcaagttct ttggcggtga tggcttcaaa ctagatgatg aaaaagaagc
    27721 agaaattgaa gccttgctag atgctgagga agacactctt cctcgtccaa gtgcagaagg
    27781 cttaggaatt ttggtagatt atccagaagg cttgcgtaag tatgaaggat accttgtttc
    27841 aactggaact cctcttgatg gaatgaaggt tgccttggat acagctaatg gagcagcttc
    27901 taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa ttgacggtta tcggggaaac
    27961 accagacggt cttaacatca accttaatgt tggttcaaca catccagaag cccttcaaga
    28021 agtggtcaaa gaaagtgggt cagctattgg tttggccttt gatggagaca gtgaccgctt
    28081 gattgctgtt gatgagaatg gtgacatcgt cgatggtgac aagattatgt acatcatcgg
    28141 aaaatacctt tctgaaaaag gacaattggc tcaaaataca attgtgacaa ctgttatgtc
    28201 taaccttggt ttccacaagg ccttgaatcg cgaaggtatt aacaaggcag ttactgcagt
    28261 tggtgaccgc tacgttgttg aagaaatgag aaaatcaggt tacaaccttg gtggtgaaca
    28321 gtctggtcac gttatcttga tggattacaa taccacaggt gatggtcaat tatcagcaat
    28381 tcaattgact aaaatcatga aggaaactgg taagagctta tcagagttgg cggcagaagt
    28441 aacgatttat ccacaaaaat tagttaatat ccgagtggaa aacgtcatga aggaaaaggc
    28501 catggaagtg ccagctatca aggccatcat cgagaagatg gaagaagaaa tggcggggaa
    28561 cggccgtatc cttgttcgtc caagtggaac agagcccctc ttgcgtgtta tggcagaagc
    28621 gcctacaaca gaagaagtgg actactatgt tgatactatc acagatgtag ttcgtgctga
    28681 aattgggatt gactaaatcc tagaaaacta gatgaaaata aaaaattatg gtacaatagc
    28741 ttataatatt gtagccgatg gagaaagaca tgaatcttaa acgtgaacaa gaatttgtta
    28801 gtcagtatca ttttgatgca cgtaattttg aatgggaaaa tgaaaatgga gctcctgaaa
    28861 ccaaggtgga tgtgaatttc caattgctcc aacatgacca agaaaatcaa gtgacttcct
    28921 tgattgtcat tttgagcttt atgattgtat ttgataagtt tgtcattagt ggaacaatct
    28981 cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc aagtgaattg aaccaagaag
    29041 aggtggaaac cttggctcgt ccatgtttga acatgctcaa tcgtttgact tacgaagtga
    29101 ctgaaattgc attagactta ccaggaatta atttggagtt ctaatatgaa attagctgtt
    29161 ttcacagatt cctctgctta tctcagtgaa gagaccttgc aaagagaaga cttgtttgtc
    29221 ttggatattc ctgtcaatat tgatggtgag gaatatgtcg aaggcatcaa tctgtctgct
    29281 gaggaatttt accaaaaaat ggctcaggct tctgaattgc ctaagaccag tcaaccaagt
    29341 attgccaagt tagatgagat cttaacttcg ctcaaagaac aaggctatac acatgccttg
    29401 gggcttttcc tatcttctgg aatttcaggt ttttaccaaa atatccagta tatggtcgat
    29461 gactatgagg gcttaaccat tgctttccca gacactttga ttacaagtgc tcccctaggc
    29521 atcatggttg aaagcgtctt taattggcgt gatcagggcg atgattttgc cagcattcag
    29581 gataagctag ccattcaaat cagccgtacg tcagccttta tcatggtaga tgacttggat
    29641 catttggtaa aaggtggacg cctttcaaat ggggctgcca ttttgggcaa tttgcttagc
    29701 attaagccaa tcctttattt taacgatcaa ggtgtgattg aagtttacga aaaagttcgt
    29761 actgaaaaga aggccaccaa gcgcttaatt gaaattatca aggaaacaac ggcttcaggt
    29821 caataccggg tcattgtcat tcatgggaat gctcctgaaa aggctgaaga attgcgtcag
    29881 cacttgcttg attttggctt gggttcggat gtttcacttg ctacatttgg tagtgtcatt
    29941 ggaacgcacc taggagcagg aagtattgct ctgggttata ttccagtgat ttagttggcg
    30001 cttctaggct agttaagatg ccttgtatct tagaaattga acacggacta cctgcctctt
    30061 gaaaaaagat gcctgtcttg cctttcgtgg aaagtcagtg ccattcccta tttttcagag
    30121 gcagctaagg tcctttgtat cttgataatt gaacacgcct ggaaccctgt gtgaaaaaga
    30181 tagttcttcc aagaagtaga cacttcttga ttggaattcc tattttcact ttgtgttctt
    30241 acggactttg tatcttagac aggagtagag atgagtattc gagtaattat tgccggtttt
    30301 aagggaaaga tgggccaggc tgcttgtcag atggtattga ctgatccaga cttggacttg
    30361 gtggcagttt tggatccttt tgagtctgag tcagaatggc agggtattcc tgttttcaag
    30421 gataaggctg atttagctgg ttttgaagcg gatgtctggg tagattttac tactccagct
    30481 gttgcctacg aaaatacacg ttttgctctt gaaaatggct ttgctccagt agttggaacg
    30541 actggtttca cgagtgaaga aattgcagag ctaaaagaat tttctcgtgc ccaagacttg
    30601 ggtggcctga ttgcccctaa ctttgccttg ggtgctgtct tactcatgca atttgcgacg
    30661 caggctgcca aatatttccc aaatgtggag attattgagc tccatcatga caagaaaaag
    30721 gatgctccga gtggaacagc cattaaaaca gctgagttga tggcagaggt tcgagagtcc
    30781 attcagcaag gcgcagcaga tgaggaagag ctgattgctg gtgctcgtgg tgctgacttt
    30841 gatgatatgc gcatccactc agttcgtttg ccaggcttgg tagctcatca ggaagtcatc
    30901 tttggcaatc agggagaagg gttgaccctc cgtcatgact cctatgatcg catctccttc
    30961 atgacaggag tcaatttggg aattaaagaa gttgtcaagc gtcatgagct tgtctatgga
    31021 ttagaacact tattatgaga ttaacgcaaa tgccttctga atttcagaag gctttaccag
    31081 tattagaaaa aattaaagaa gcaggctttg aggcttattt tgttgggggc tctgttcgag
    31141 atgcccttct ccatagccct atccacgatg tggatattgc gacgtcttct tatccagaag
    31201 agaccaagca gatttttccg cgaacagccg atatcggaat cgagcatgga accgtcttgg
    31261 tcttagatgg ggatgaggag tatgaggtaa caacctttcg gacagaggat gtctatgtgg
    31321 actatcgcag acccagtgcg gtttcctttg tacgatcgct agaagaagac ctcaaacgcc
    31381 gtgatttcac agtcaacgcc tttgccttgg atgagacagg agaaatcgtt gacttgttcc
    31441 atggtttaga agatttggaa aagcaagtct tgcgagcagt tggagtggct agtgagcgtt
    31501 tcaacgaaga tgctttacgg attatgcgtg gtttccgttt tcaggctagt cttggttttg
    31561 cacttgagcc agaaacattt aaagctatga agaccttgac gccgcttttg gagaaaattt
    31621 ctgtagagcg taccttcgtc gagtttgata aactcttgct ggctccattt tggagaaggg
    31681 gcttggcttc catgattgag agtcaagctt atgactatct ccctgatatg gcatctagcc
    31741 aggacaagct caacagactg tttgatttgg agactgattt tacttttgaa tcctctgaac
    31801 aagcctgggc ggctttacta tgggctttgg agattgaaaa tgcgcagtca tttttgaaat
    31861 cttggaagac ctcacgccag tttgccaagc aagttcagga tttgctgatt attttggctc
    31921 tgcgtgaaaa tggagaattg agtaagcgag attgttatcg ctttgacata gatttgcttt
    31981 tacaggctga aaatcttcgt caagctcaag gaaaagaagt caacccacaa gccatcacag
    32041 aaaaatacca aagcttgact atccatgaca agaaagagat tcagattaat ggcgatattt
    32101 tgatcaagga atatggctat cagccaggcc cagacttggg agagatttta acagagattg
    32161 agtttgccat tgtcgatgga gaattggaga ataatcgtga agccatccat gcttacctga
    32221 gggagaaaaa atgagtgatt ttatcgttga aaaactaagt aaatccgttg gtgacaagac
    32281 cgtttttagg gatatttcct ttattatcca tgacttagac agaattggtt taatcggtgt
    32341 caatgggact ggcaagacca cccttttgga cgtcctttct ggtgtttctg gatttgatgg
    32401 ggatgtcagt cctttttcag ctaaaaatga ttaccagatt ggttacttga ctcaggatcc
    32461 tgattttgat gatagaaaga cagttttgga tacggttcta tctagtgaac tcaaggaaat
    32521 ccagctcatt cgtgagtatg aattgattat gctcgactat agtgaggaca agcaggcgcg
    32581 tttggaacgt gtcatggcag agatggactc tctccaagct tgggaaatcg aaagtcaggt
    32641 caagaccgtt cttagcaaat tgggcattca agacttatct actcctgttg gggaattgtc
    32701 aggtggtctg agaagacggg tacagttggc acaagtctta cttggcaacc acgacctctt
    32761 gcttttggat gagccgacca accatctgga tattgcgatt attgagtggc tgaccctctt
    32821 tttgaaaaat tctaagaaga ccgtcctttt tatcactcac gatcgttatt tcttagacgc
    32881 tttgtcaaca cggattttcg agttggatcg tgcaggcttg accgagtacc agggcaatta
    32941 ccaggactat gttcgcctaa aggcggaaca ggatgagcgc gacgcggctc ttcttcacaa
    33001 aaaagaacaa ctctacaaac aagaactggc ctggatgcgc agacaaccgc aggcgcgtgc
    33061 gaccaagcag caggcccgta tcaatcgatt ccatgatctg aaaaaggaag tttcaggcag
    33121 tagtgctgag acagacttga ccatgaactt tgaaaccagt cggattggga agaaagtcat
    33181 cgagtttcag gctgtttcct ttgcctatga aaacaagcct attttgcaag attttaatct
    33241 cttggtgcag gccaaagacc gtatcggaat cgttggggac aatggtgttg gaaaatcaac
    33301 cctgctcaac ttgattgcag gaagtcttga gccaactaaa ggacaagttg tgattgggga
    33361 aactgttcgc atcgcctatt tctctcagca aattgagggt ttggatgaaa gcaagagagt
    33421 tatcaattac ctgcaggaag tggcagaaga ggtcaagacc agtggcggtt ctacgacttc
    33481 gattgcagag ttgctggagc agttcctttt cccacgttcg acgcatggaa ccttgattga
    33541 gaaattgtca gggggtgaga aaaaacgtct ttatctcctc aaactgcttt tggaaaaacc
    33601 aaatgttctt cttttagacg agccaaccaa tgacctagat attgcaactt tgacagtctt
    33661 agagaatttc ttgcaaggtt ttgcaggtcc cgttttaaca gtcagtcacg accgctattt
    33721 cttggataag gtagcgacca agattctcgc ttttgaggat agcaagattc gtcctttctt
    33781 tggtcattac accgactatc ttgatgaaaa agcttttgaa acagatatgg ccaatcaagt
    33841 gcaaaaggtc gaaaaggaaa aagtggtcaa ggttcgagaa gacaagaaac gtatgaccta
    33901 ccaagaaaag caggagtggg caagtattga aggtgatatt gaaaccttgg aaaaacgtat
    33961 cgctgctatt gaagaggaaa tgcaggctaa cggctctgac tttggtaagc tggctactct
    34021 ccaaaaagaa ttggatgaga aaaatgaagc actccttgaa aaatacgaac gctatgagta
    34081 tctcagtgaa tttgatagtt aagactattc gaaaatcaaa gtgcaaacta tgtcggcttc
    34141 acattgccga ctcaagtaca gcctgtgacc ggcttcctaa tttgcacttt gatttttatt
    34201 gagtataaaa gaatagaaaa atcccgtctc atgaaaggat ttctctattc ttttttggtt
    34261 tcttgatgaa agatattttg ccaggtttcg tggcgacgcc agatactggt atggatgata
    34321 ccatctaact catagcagat gagtttggtt ttttgactga tggaagtaat ttgaatgtcc
    34381 ttgatagcag aatttaactc ttttttggtc ttataagcct ctttatccat ctgctctcca
    34441 tcttggcgaa tatagacaaa atcatcagtc aagagttctt ctagttggtt tccttggtca
    34501 atcaattgtt cacgcataag caatttttta tagacattgt ctaaaatttc atcctcagag
    34561 ataggtgctg gttcgatatg gacatcggta tcaaagacgc caaaacgctc ctccagcata
    34621 gactcgacct gatccgcgat ttcatggctt tcaaaaacag acaagtcagg attcatctct
    34681 agtgtaatat ccaggtagat gttgctaccg taggtgcgac ctctttgcga tttgaccttg
    34741 ctgattttgg gaatttccat gatagccttt tggtagtcct cgagcaggcg gtcgtcaaag
    34801 ccatctgaaa gactaaagga agactcgatg aagatatcat aggcagtctt caagataaag
    34861 aaagtgatga tgatagcaac cagtttatcc acaatcggat aattgaaact actagctagg
    34921 atggcaatgg cggttccaag tgaggtaaca gcgtcagaaa gattgtcctt agcagctgcc
    34981 ttcagcgcct tggagttgga tttcttactg aggcgagtat tgtagagata gaccacaaac
    35041 ataatcgctg cagaaatgat tcctagagtt gcaccaagag gatcaatgac cgtttcttcc
    35101 cgactgagaa tcttttgaat ggtatctctt agaacatcga aaccgacata gaacatgatg
    35161 atagaagtga tcaagcttgc caaatcttca atcttccaat gaccaaaacg gtggtcacgg
    35221 tctgcaggct ggcgcgccat ccgaatcccg attaagaggg ccacatttcc aatgatgtcc
    35281 gatacgttat taaaaccatc ggccaccaaa ctggatgaat gaaggagatg accagctgct
    35341 aatttggctg cagacaagat caaataggtc gaaatactga taatggctcc acgctcagct
    35401 aacttgagat ttgagataga ttgcttcatt caacttcctt tctagtcaca tagcattcta
    35461 ccattatact ggttttcaag gaaaaattca aataaggcag tttttactct ttgaaaactc
    35521 cccaaaattt ggtataatgg tactactcaa gggagtagct ggcagaaacc tgtgatagtg
    35581 tcgtcattcc gaattttatg ctgaaaagta tgctttccgg ccctatctta aacagcgaga
    35641 cttgttatga ttaacaggtc tctttttgtt tgtcgtgaaa agatatgaca gaaagagagt
    35701 ctgttttgca cacaatgtca aggaggagac acatgtcaaa agaacaaaaa cgccaagcgt
    35761 tttatactca gagccctgaa gaggtcttgc aggctgtgga tgcgaccgag caaggtttgt
    35821 catcaagtga ggcggaaaag cgccttgctg aatttgggca caatgaactc gaagaaggcg
    35881 agaaacgatc aatcttggtc aaattcatcg agcaatttaa ggatttgatg attatcatcc
    35941 tagttgcggc agcaatcttg tcagtcgtga cttctggtgg ggaagatatc gcagatgcca
    36001 ttatcatcct agctgtggtt atcatcaacg ctgcctttgg tgtttaccaa gaaggaaaag
    36061 ctgaagaagc tattgaagcc ctcaaatcca tgtctagtcc agttgcccgc gttcttcgtg
    36121 atggacacat ggcagagatt gactctaaag aattggtacc aggcgatatc gttgcccttg
    36181 aagcaggtga cgtggtacca gcggacctac gtttgataga agccaactct cttaaaattg
    36241 aagaagcagc cttgacaggt gaatctgtac cagtcgaaaa agacttgtca gtcgagcttg
    36301 cgacagatgc tggtattggt gaccgtgtca acatggcctt ccaaaactca aacgtaacct
    36361 atggtcgtgg gatgggtgtt gttgtcaata caggtatgta cactgaagtt ggtcatattg
    36421 ctggtatgct tcaagatgcg gatgagactg atacaccact caaacaaaat ttgaacaacc
    36481 tttctaaggt cttgacctat gctatcttgg tcattgccct tgttactttt gtagtgggtg
    36541 tcttcattca agggaaaaat ccacttggtg agttgttgac ttctgttgcc cttgccgttg
    36601 cagccattcc agaaggactt cctgctatcg ttaccatcgt tctttctctt ggtactcaag
    36661 ttttggccaa acgacattcc atcgttcgta agttgccagc agttgaaaca cttggttcaa
    36721 ctgaaatcat cgcttctgat aagactggta cgctgactat gaacaagatg acagtcgaaa
    36781 aagtcttcta cgatgcggtt ctacatgact cagctgatga tattgaacta ggtcttgaaa
    36841 tgccactact tcgttcagtt gtcttggcca atgatacgaa aatcgatgtg gaaggtaact
    36901 tgattggtga cccaaccgaa acagccttta tccaatatgc cttggacaag ggctatgatg
    36961 tcaaaggttt cttagagaaa tatcctcgtg tagctgaatt gccatttgac tctgaccgta
    37021 agctcatgtc aacagttcac ccattgccag atggtcgttt ccttgtagca gtcaagggtg
    37081 cgccagacca actcttaaaa cgttgtcttc ttcgtgataa ggctggggat attgctccga
    37141 ttgatgagaa ggttacaaat ctcattcata caaacaattc tgaaatggct catcaagcct
    37201 tgcgtgtcct tgcaggtgct tataagatta tcgatagtat tccagaaaat ctcacttctg
    37261 aagagcttga aaatgattta atttttactg gtttgattgg gatgattgac cctgaacgtc
    37321 ctgaagccgc tgaggctgtt cgtgtggcta aggaagcggg aatccgtcca attatgatta
    37381 caggtgacca ccaagacaca gcggaagcca ttgccaaacg tttgggaatc attgacgcaa
    37441 acgatacaga aggtcacgtt ttaactggtg ctgaactcaa tgaactgtca gatgaagaat
    37501 ttgaaaaagt cgttggtcaa tactctgttt atgcccgtgt gtctccagaa cacaaggttc
    37561 gtatcgtcaa ggcttggcaa aaacaaggta aagtcgttgc catgacaggt gacggtgtca
    37621 atgacgcgcc agctctgaaa acagccgata tcggtatcgg tatgggaatc actggtacag
    37681 aggtttctaa gggggcttct gatatgattc ttgcagatga taactttgcg actattatcg
    37741 tcgcagtgga agaaggacgt aaggtcttct caaacattca aaagactatt cagtacctac
    37801 tttctgctaa tactgctgaa gtattaacca tcttcctatc aaccttgttt ggttgggatg
    37861 tcttacagcc ggttcatctt ttgtggatta acttggtaac ggataccttc ccagctatcg
    37921 ctcttggtgt tgaacctgcg gaacctggtg tcatgaatca taaaccacgt ggacgcaagg
    37981 caagcttctt ctcaggtggt gttttgagtt ctatcattta tcaaggtgta ctccaagcag
    38041 ctcttgttat gagtgtttat ggccttgcga ttgcttaccc agttcatgtg ggtgacaatc
    38101 atgctattca tgcagatgcc ctaacgatgg cctttgcaac ccttggtttg attcagctct
    38161 tccatgccta caatgtcaag tctgtctacc aatccatctt gacagttggc ccattcaagt
    38221 ctaagacctt taactggtcc atcttggtat cctttatcct tctcatggca acaatcgttg
    38281 tagaaccgct tgaaggaatc ttccacgtaa ccaaactaga cttgtcacaa tggggaattg
    38341 ttatggctgg aagcttctca atgattatca tcgtcgaaat cgttaagttt attcaacgca
    38401 aactcggttt tgacaagaat gcgatttaag ggaggtttcg gatgtcagca tatcaattac
    38461 cgaccgtatg gcaggatgaa gctagtaatc aaggagcttt tacggggcta aacagaccaa
    38521 cagcaggtgc ccgtttcgaa caaaacttgc caaaaggaga acaagctttt cagctttatt
    38581 cactgggaac accaaatggt gtgaaggtta ctatcttatt ggaagaatta ctagaagctg
    38641 gttttaagga agcggcttac gacttgtata agattgctat catggatggg gatcaattcg
    38701 gctcagactt tgtgaagctc aatccaaatt ccaagattcc agccttattg gaccagtcag
    38761 gtactgaaaa cgtaagagtc tttgagtctg ctcatattct tctttacctt gctgagaaat
    38821 ttggagcctt tttaccaagt aatcctgtgg aaaaggtaga agttttgaat tggctattct
    38881 ggcaagcagg tgcagcacct tttctaggtg ggggatttgg acatttcttc aattatgctc
    38941 ctgaaaaatt ggaatatcct attaaccgtt ttacgatgga agtgaaacgc cagttggatt
    39001 tattggataa ggaattggct cagaaacctt atattgcagg caatgactat acgattgcag
    39061 atattgctat ctggtcttgg tatggacagt tagttcaagg aaatctttac caaggttctg
    39121 caaaattctt ggatgcctca agttatcaaa atctagtaaa atgggcagaa aaaattgcca
    39181 atcgtccagc tgttaagcgt ggcttggaag taacttatac agaaattaaa tagcaaaaaa
    39241 gtcatcttcg gatggctttt tgctacagtt gagggaaagg gtttgcagtt atcggctttt
    39301 gtgctataat tgctataata tagtaaaaag caagaggagt gtgaggaagt ggaaaagaaa
    39361 attgtgaagg atatcttatt tttatctcaa gtgtctcatc cggcaagtca ggaggacctt
    39421 tatcttgcca gagatttgca ggatacactc ttagcaaatc gtgatacctg tgttggtcta
    39481 gctgccaata tgattgggat gcagaagcgc gtgattatct ttaatcttgg cttggttccc
    39541 gtggtcatgt ttaacccagt gcttctgtcc tttgaaggat cctatgaggc agaagaaggc
    39601 tgtttgtcct tggtaggtgt gagatcaact aagcgttatg aaaccataag gcttgcctat
    39661 cgtgacagca agtggcagga acagaccatt accttgacag gcttcccagc tcagatttgc
    39721 cagcatgagc tggatcactt ggaaggacga atcatttagg aggaaagcaa atgaaacgaa
    39781 tagtctttga acttattttt atcgcaacga cctggtatat ctttttaccg ccccttaacc
    39841 tgaccagctg ggaatttctc ttcttcctct gtgggcattt gttagttgtg gcaatcttat
    39901 ttggctttgg caaggggata aaccttgtca aaacggttca tgtgcgccac ggtaaggcgg
    39961 aagctgcctt aaatcttgag ggtttcaaaa tcaatcggtt agggaaaatt ctgttagctt
    40021 cgattggagg aattcttctc ttggcagctt tggtttcctt ggtaacttct agcatgtttc
    40081 aggctaaaaa ttatgccaat gtagtcacgg ttacggaaaa agactttact gaatttccta
    40141 agagtgacac cagtaaggtt cctatcctag atagaagtac tgctgaaaaa attggagacc
    40201 gctacttggg ttccctaacc gataaggtgt cgcaatacgt agcggcagat acctataccc
    40261 aattgacaat tgatgggaaa ccttatcggg tcacaccact agaatatgca gaccctatca
    40321 aatggtttaa caatcaagcc aagggaatcg gtgagtatat caaggtggac atggtaactg
    40381 gaaatgcgga tttggtggac ttgaagacac caatcaagta ttcagactcg gagtatttta
    40441 accgtgatgt caaacgtcac ctgcgcttga agtacccgac caaaatcttt aaaactccat
    40501 cttttgaggt ggacgatgag ggcaatcctt tctatgtagc aacggtttac caaaagcaat
    40561 ttggacttgc tgttcctcgt cctgcttcag tcattatctt ggatgctaca aatggagaaa
    40621 ccaaggaata cagcttatca gatgttccag aatgggtgga caggatctat ccagcagagg
    40681 aaaccattga gcaaatcaac tacaacggca agtacaagga cggtttcttg aatgccatga
    40741 tttccaagaa aaacgtgacc cagacgacca atggctataa ttacttgtct atcggtaatg
    40801 acatctatct ctacacaggt gtgacgtcgg ctaatgcgga tgagagtaat cttggtttca
    40861 tccttgaaaa tatgcgaaca ggagaaatta ctaagtatag cttggcttct gcgacagaag
    40921 aatcagcccg tgaatcagca gaaggtgctg ttcaggagaa atcctacaaa gcaaccttcc
    40981 caatcctcat caacctcaat gacaagcctc tctacatcat gggcttaaag gacaatgctg
    41041 gcttggtcaa agagtacgcc ctggtagacg cagtcgagta ccaaaatgtt atcgttgcta
    41101 ctacagtgga agagatgctc agcaagtatg ccaataaaaa cgaccttgaa attgacaatg
    41161 caacgacaga aagcatcaag ggagtagtag cagacctcaa atcagctgtt atcaagggag
    41221 acactgtcta cttctttaaa gttgatggca agatatacaa ggtaaaggct tcagtatccg
    41281 atgaccttcc ttaccttgaa aatggtaaaa ccttcgaagg tcaagtagga aaagacaatt
    41341 atctcaagac ctttaaagta caataatact cttcgaaaat ctctagctct atctgcaacc
    41401 tcaaaacagt gttttgagca gcctgcggct agtttcctag tttgctcttt gattttcatt
    41461 gagtataaaa aaggtttatt taataaatat atgttataat aaggtaaatt aagcctaatg
    41521 gaggacaaag aaatgggttt ttatttgatg gttgcttcaa tgctactcgg actgctcgct
    41581 ttgaagatag gtttttctca gttcaaggag aaaaaagata aattcttatc tatcttaaca
    41641 agtttagctg gcacagccct tgttctcgtg gctgtctggt taggatggcc caaataaata
    41701 gaaaaacctc ggtcaaaccg aggtttttca aatgaatttc ttggttgtgg ctaaaaaata
    41761 tgctacacta tcaatatgaa aattttaatc ccaacagcaa aagaaatgaa cacagacttg
    41821 ccaagtatcg aggcaattcc tttaaaacca gaaagtcaga ccgtgcttga tgccttggct
    41881 ctctattctg ccagtcaatt ggagagtttc tacaaggtat cagctgagaa agtggcggaa
    41941 gaatttcaaa atatccaagc tttgaaaagg caaactgctc aacactatcc agccttgaaa
    42001 ctttttgatg ggcttatgta ccgcaacatt aagagagata agctgaccga ggcggaacaa
    42061 gattatcttg aaaatcatgt cttcattacc tcggctttgt acggtgttgt tccagccttg
    42121 tcacccatgg ctcctcaccg tttggatttt ttgatgaaat taaaagtcgc tggtaagact
    42181 ttgaagagcc attggaaggc agtctatgat gaagctctga agaaggaaga agtgattttc
    42241 tctctcttgt catcagagtt tgagactgta ttttctaagg aaatcagagc aaagatggtg
    42301 accttcaaat tcatggagga tagaggcggt cagctgaaga ttcactcaac tatctccaag
    42361 aaagcgcgcg gggcctttct aacagcttta atagaaaatc aagtacaaac tgtgggggaa
    42421 gcacgtcgct tgaactttgc tggatttgtt taccgagaag atttgtcaca accacaggga
    42481 ttggtttttg taaaggaagt atagaaatca gataagagaa aagtcagcac gattatgctg
    42541 acttttttga taacttataa agtattggac aaatgaatct catttgataa ggtgttaaga
    42601 tgattaacca aattcatgat tgacagatga tttcggcaaa taaacttctt ggtaatccct
    42661 gaaatataga aattagacac gatgatatcg taatctgtct gatttaaaat ctcaggactt
    42721 gtttttaatt catcccaaat atcgaaggta aagcggttat tacagtaata ggaaagcata
    42781 tcaacaaagg taagggatat agcatggtca aagttactga taatcaaaac cttgataggt
    42841 ggtcgatttt ctaacaactg agtagagagg ttttcagcat gggttaagat ggtgtacatc
    42901 aagtgttcca actgttcagg atggtcatgc tgtccaattg cctgacggta ttgagccagt
    42961 tcttgacgcg cacttcccat aaagtctggg aagtaacctt caaatttttt aatcgtcaat
    43021 gctttttgtt caaataagat tggggtagaa aagatttcct gtctttcaaa gaaagcagtg
    43081 ttgtgtaaat gccaaatcag ctcatcgtgg ttagtaaaag taatcttata ttgttttgat
    43141 aggcgttcta atatttgact aagtaattgg taagagtatc ttgcttgact gttatcttct
    43201 aaagagttga agaattcttg aggatctagg aaaatatcat tctgaagaaa agaaataaaa
    43261 atttgagcga ttgtatctgg agtcatttca agcccaaaat gtttagagaa ataagcaagt
    43321 gtctcctgga aatttggaat gctctttaaa agaggataat attctttgta aaagtggttg
    43381 gggaggtcaa tgaagtgacc atttttaacc ctgtggatac tgatagctat catcagtttg
    43441 tacattctat aaattgaaaa tcgcattgga taattcgtga ttttatagaa gaagtcagca
    43501 aactctgtta aatcttcctc aggaaggtca ggaaaaggcc aatctaggaa ataatagcgc
    43561 tcagaaaagt attgggcaaa aaagtaacga atatcgatct catttccacg tatctcggat
    43621 ggagtaaaag ataattcaat ttgaaactga gatgaaagaa cctttgtaat atttctgccc
    43681 agtcgataga ggttggcact actaaagtaa agattttcta ttgttcgata aataggtagc
    43741 ccctcattga agaacatata ctctagtaat tgaaaagatt gagaattagc aagaaaatat
    43801 tgataaatat cttctacact agtgttaact tctaaatcta tcatgattcc gttaacagaa
    43861 gattggatgt taatagatgg aaaggcaata cgtaattcat ttaaatcact ttttaagatt
    43921 cgttctgtac atcctaattt ttcggctagt tcatgtaatt tcatccaatt acgattctga
    43981 attagggttt ccattaagcg taattgtctt tgaacttttg tggataaaag gtttctcata
    44041 cgggtatttc ctccataatt cattatatct ttttttgtct aagtagtata aaaaaattag
    44101 agcaagaaaa ttgtcgttag taatcggaaa aattagaata atataagtgg cttttaagtg
    44161 caaaaacaga atatattaat tgttcagaaa atattgatta atgcctcaaa tagttgtaca
    44221 ttgtaaacta taaaatacta tctaggagtt taaaatgaaa cattcacata aaaaatcatt
    44281 tgactggtat agcatgcaac aacgttattc tattcgtaag tattactttg gtgcagttag
    44341 tgtcttgctc ggtaccgctt tggtattagg tgcagcagct agtgtccaaa cagtacaagc
    44401 ggaagaaaac aaacaagaaa ctaccaatag tatttctgtt ggtaggggag aagcagctac
    44461 taaaccagca gaggtttctg cgtctaataa agagaaaacc tatgcagctc caactgtagc
    44521 taatccagta gaaacgactc cagttaaaac tggagaagtt actaaaccag cagaaaaagt
    44581 tgaagaagca aaagacaaaa aagaggaagt aacgcatcaa gatgctattg acaagtcaaa
    44641 attgttaacg gctctttcgc gtgctaaaaa gttagaaagc aagttatata cagaagcaag
    44701 tgctgctaac ttgcaaacaa gtatccaagc tggtcaaagc ttgcttggga aagcagatgc
    44761 atctgaagct gaattatcag cagcagagtc atctattcaa tcatctatta ttggtctaga
    44821 acttcgttct aactctaaca aaggaactgt atcagaaact cctgtagcga agaaagctaa
    44881 tatagttgaa gcgaaggaag agactaatcc agctgcaaca actgatcgtt cagctgttga
    44941 tagtgctgtt ttgccaacta gcacagctgc caaagtagaa acaacttcag ctccagcatc
    45001 tattaatgaa atcttgaaac caggtttgag cctttctgat gctcgccaaa atccagctat
    45061 ccgtaaggaa gatgttgata gagggtatag tggttttaga gcggcgcctg ctccaacgaa
    45121 ccaaccagta actaatctag gaaataatac tgttttcact gatattagca gaggttctca
    45181 tactttccgt ggtaatggaa attcacgtcg tggaaacccg attcattttg atgtaacaac
    45241 aactagagtt agaaatagag tagatttctc aatcagatat tcaggaccag gtgagtttgt
    45301 taataacaac tttatcttag acaaaggaaa tggattcgga gaaccttctc gtgcaactgt
    45361 ttcaacacca aaattaagag accaagttaa aaacattagt aagggtggaa actttgtttc
    45421 tcattcaggc tacagtttag aagctgcagt agaaacaagc accaatcaaa caattaagtt
    45481 tagtttacct atagccaacc ctaatggtga tctgtctgtt cgattaagac ctgttacttt
    45541 taatgtaggt caaggggaat caggatctgc aactagtaat gatccatata gtaactctaa
    45601 ctattacttc agagaaaaac cactcctctt ggatgcaaat ccaaatggtg gtactaataa
    45661 taagactgtt tcagaagaca ttgacttcca aactgtctat cttccaacta gtaagttacc
    45721 agaaggtcaa actagattag ttcgagaagg tgaaaaagga caacgtcaaa tcatctataa
    45781 agttcatcaa ttgggtaacg aaacaatcct aggattgcca attagtaatt cagttattaa
    45841 agaagttaag ccacgtatta tgcaaattgg tgtggctaaa gatctaatcg atacagtaaa
    45901 accacgtgtt gatcaaaata aagtcggtga tacaaataac ctcactttct atcttgataa
    45961 cgatggaaac ggtgtttata ctgagggcgt agacgaactt gttcaaaaaa ttgctattaa
    46021 agatggtgct aaaggtgaaa aaggagaccg aggcgaacgc ggtctaactg gagctcaagg
    46081 agctaaaggt gaaaaaggag accgaggtga acgcggtcta actggagctc aaggagctaa
    46141 aggtgaaaaa ggagaccgag gtgaacgcgg tctaaccgga gctcaaggag ctaaaggtga
    46201 aaaaggagac cga
//
LOCUS       DAVBED010000009        45404 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBED010000009 DAVBED010000000
VERSION     DAVBED010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.009"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(1..82)
                     /locus_tag="VQ547_000521"
                     /pseudo
     CDS             complement(1..82)
                     /locus_tag="VQ547_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(144..593)
                     /locus_tag="VQ547_000522"
     CDS             complement(144..593)
                     /locus_tag="VQ547_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2542427.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(595..1353)
                     /locus_tag="VQ547_000523"
     CDS             complement(595..1353)
                     /locus_tag="VQ547_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2542428.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1468..3447)
                     /gene="pknB"
                     /locus_tag="VQ547_000524"
     CDS             complement(1468..3447)
                     /gene="pknB"
                     /locus_tag="VQ547_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2542429.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3444..4184)
                     /locus_tag="VQ547_000525"
     CDS             complement(3444..4184)
                     /locus_tag="VQ547_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2542430.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4199..5512)
                     /gene="rsmB"
                     /locus_tag="VQ547_000526"
     CDS             complement(4199..5512)
                     /gene="rsmB"
                     /locus_tag="VQ547_000526"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2542431.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5505..6440)
                     /locus_tag="VQ547_000527"
     CDS             complement(5505..6440)
                     /locus_tag="VQ547_000527"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2542432.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6453..8849)
                     /locus_tag="VQ547_000528"
     CDS             complement(6453..8849)
                     /locus_tag="VQ547_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2542433.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(8915..9229)
                     /locus_tag="VQ547_000529"
     CDS             complement(8915..9229)
                     /locus_tag="VQ547_000529"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2542434.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9254..9880)
                     /gene="gmk"
                     /locus_tag="VQ547_000530"
     CDS             complement(9254..9880)
                     /gene="gmk"
                     /locus_tag="VQ547_000530"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2542435.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10010..11623)
                     /locus_tag="VQ547_000531"
     CDS             complement(10010..11623)
                     /locus_tag="VQ547_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2542436.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11814..12068)
                     /locus_tag="VQ547_000532"
                     /pseudo
     CDS             complement(11814..12068)
                     /locus_tag="VQ547_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12072..12326)
                     /locus_tag="VQ547_000533"
     CDS             complement(12072..12326)
                     /locus_tag="VQ547_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2542437.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12564..13661)
                     /locus_tag="VQ547_000534"
     CDS             complement(12564..13661)
                     /locus_tag="VQ547_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2542438.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13671..14411)
                     /locus_tag="VQ547_000535"
     CDS             complement(13671..14411)
                     /locus_tag="VQ547_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2542439.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14731..15084)
                     /gene="rsfS"
                     /locus_tag="VQ547_000536"
     CDS             complement(14731..15084)
                     /gene="rsfS"
                     /locus_tag="VQ547_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2542440.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15097..15597)
                     /locus_tag="VQ547_000537"
     CDS             complement(15097..15597)
                     /locus_tag="VQ547_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2542441.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15598..16191)
                     /gene="yqeK"
                     /locus_tag="VQ547_000538"
     CDS             complement(15598..16191)
                     /gene="yqeK"
                     /locus_tag="VQ547_000538"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2542442.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16191..16820)
                     /locus_tag="VQ547_000539"
     CDS             complement(16191..16820)
                     /locus_tag="VQ547_000539"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2542443.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16872..17183)
                     /gene="yhbY"
                     /locus_tag="VQ547_000540"
     CDS             complement(16872..17183)
                     /gene="yhbY"
                     /locus_tag="VQ547_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2542444.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17397..18503)
                     /gene="yqeH"
                     /locus_tag="VQ547_000541"
     CDS             complement(17397..18503)
                     /gene="yqeH"
                     /locus_tag="VQ547_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2542445.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18506..19096)
                     /locus_tag="VQ547_000542"
     CDS             complement(18506..19096)
                     /locus_tag="VQ547_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2542446.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(19048..19956)
                     /locus_tag="VQ547_000543"
     CDS             complement(19048..19956)
                     /locus_tag="VQ547_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2542447.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(20013..20573)
                     /locus_tag="VQ547_000544"
     CDS             complement(20013..20573)
                     /locus_tag="VQ547_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2542448.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20712..21921
                     /gene="sstT"
                     /locus_tag="VQ547_000545"
                     /pseudo
     CDS             20712..21921
                     /gene="sstT"
                     /locus_tag="VQ547_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21989..22942
                     /locus_tag="VQ547_000546"
     CDS             21989..22942
                     /locus_tag="VQ547_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2542449.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23178..23258)
                     /locus_tag="VQ547_000547"
                     /pseudo
     CDS             complement(23178..23258)
                     /locus_tag="VQ547_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23313..23537)
                     /locus_tag="VQ547_000548"
     CDS             complement(23313..23537)
                     /locus_tag="VQ547_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2542450.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(23542..23721)
                     /gene="asp4"
                     /locus_tag="VQ547_000549"
     CDS             complement(23542..23721)
                     /gene="asp4"
                     /locus_tag="VQ547_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2542451.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(23723..25060)
                     /gene="gtfB"
                     /locus_tag="VQ547_000550"
     CDS             complement(23723..25060)
                     /gene="gtfB"
                     /locus_tag="VQ547_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2542452.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(25053..26564)
                     /gene="gtfA"
                     /locus_tag="VQ547_000551"
     CDS             complement(25053..26564)
                     /gene="gtfA"
                     /locus_tag="VQ547_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2542453.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(26576..28948)
                     /gene="secA2"
                     /locus_tag="VQ547_000552"
     CDS             complement(26576..28948)
                     /gene="secA2"
                     /locus_tag="VQ547_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2542454.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(28941..29381)
                     /gene="asp3"
                     /locus_tag="VQ547_000553"
     CDS             complement(28941..29381)
                     /gene="asp3"
                     /locus_tag="VQ547_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2542455.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(29378..30913)
                     /gene="asp2"
                     /locus_tag="VQ547_000554"
     CDS             complement(29378..30913)
                     /gene="asp2"
                     /locus_tag="VQ547_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2542456.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(30897..32477)
                     /gene="asp1"
                     /locus_tag="VQ547_000555"
     CDS             complement(30897..32477)
                     /gene="asp1"
                     /locus_tag="VQ547_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2542457.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(32487..33704)
                     /gene="secY2"
                     /locus_tag="VQ547_000556"
     CDS             complement(32487..33704)
                     /gene="secY2"
                     /locus_tag="VQ547_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2542458.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(33761..34438)
                     /locus_tag="VQ547_000557"
     CDS             complement(33761..34438)
                     /locus_tag="VQ547_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2542459.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(34423..34665)
                     /locus_tag="VQ547_000558"
     CDS             complement(34423..34665)
                     /locus_tag="VQ547_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2542460.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(34665..35861)
                     /locus_tag="VQ547_000559"
     CDS             complement(34665..35861)
                     /locus_tag="VQ547_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2542461.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(35870..37090)
                     /locus_tag="VQ547_000560"
     CDS             complement(35870..37090)
                     /locus_tag="VQ547_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2542462.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(37121..39565)
                     /locus_tag="VQ547_000561"
     CDS             complement(37121..39565)
                     /locus_tag="VQ547_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2542463.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(39575..40585)
                     /locus_tag="VQ547_000562"
     CDS             complement(39575..40585)
                     /locus_tag="VQ547_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2542464.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(40614..41489)
                     /locus_tag="VQ547_000563"
     CDS             complement(40614..41489)
                     /locus_tag="VQ547_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2542465.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(41529..42407)
                     /locus_tag="VQ547_000564"
     CDS             complement(41529..42407)
                     /locus_tag="VQ547_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2542466.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(42404..44489)
                     /locus_tag="VQ547_000565"
                     /pseudo
     CDS             complement(42404..44489)
                     /locus_tag="VQ547_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(44550..>45404)
                     /locus_tag="VQ547_000566"
     CDS             complement(44550..>45404)
                     /locus_tag="VQ547_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2542467.1"
                     /translation="ISASESASTSASASASTSASASASTSASESASTSASASASTSTS
                     ASESASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTS
                     ASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASAS
                     ASTSVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAK
                     RRKRDEEE"
BASE COUNT        13269 a        10197 c         8105 g        13833 t
ORIGIN      
        1 attggctccg acggagtaag ttgctttcgt ggataccaaa atcagccgca atttcttcat
       61 aagtgcggta ttctcgcaca tatagaaagc gttgttaatt tatttatctc atttttcaga
      121 aaattctttt atttctgtaa agtctacgat actcgatgtg tttttatata atgatacagt
      181 ctgagaatca ctgttccgct agccattcca atagagatta ccaaagccaa catgacaacc
      241 aaggtcgcac ttgccagtgc tttattatag tcccctgtca caaaaaaggc agttgttcgg
      301 taggagagat aacctggaac cagcggtgcc aaaatggcca agataaagac cacagcaggt
      361 gtcttataaa gaatacttaa aatctggctg acacaagaac caataatggc tgcaatgaag
      421 gtagctacaa tgacattggt cggttccttg agcaagagat agattagcca gacagtcatg
      481 cccaaaatcc ctccaggtaa gagcatagac cgttgcacat tgagtacgat taaaaaagtg
      541 ataatggcaa gaaaacttgc tactgcttgt aataaaaagg ttgttagtgt catattagtt
      601 catcaatacc aaggcgacag aagttcctgc ccctaaagcg agggtaatga gcagggattc
      661 aaacatctta ctcataccag agtttatgtg gttggtcata atatcacgga ccgcattggt
      721 caaggcaata cctggtacaa acggcatgac cgcaccagct ataatcaaat ctgccgttga
      781 aggaaaacct gtgtagcgag cccaaaactg ggcaattatc ccaaagacaa aggctccagc
      841 aaaggctgtc acaaagggaa ttcggataaa tttttccaca tagagggaaa aggcaaaacc
      901 aaataaggtc gccactcctg ccccaagtgc gtcgtagata tttccgctaa acataactga
      961 aaagaaagga gcactaaagg tcgcagccag agttacctgc aacttagtat agggaagggg
     1021 ttgagcttgc aaggccgtca attgcttaaa ggctgtttct aagtcaatct gccccccaac
     1081 tagctgacga gaaatctggt tcacatcgca gactttttcg atgttataag aagaggaggt
     1141 cacgcgcttc atgcgcgaaa tattggtatt ttcaatagag aaaaagatag cggcaggcat
     1201 ggcaaggaca ttgcaatcca caatcccctg cgaatgcgcg attcgaatca tggtatcttc
     1261 tacacgatgg atttctgagc cacttttaag gagaatagtc cccgctagca taatcacatc
     1321 aatgacggca tttaattctt ttgattcttc catgctttcc tccttttatc aactccctct
     1381 attctatcac aaatccggac tcaaaaaaaa tctttgccat gaaatcatga caaagattga
     1441 ttactcattt tgattatcca tctgctttta aggagtagct gaagttgttt taggtttgta
     1501 gattgaaatc ttgactctag tcttattgag gtctaccttt tcacctgctc taggactttg
     1561 ttcaacaacc atgccttcta cactacctgc aggcgctgtc gtcacttcta caacttctat
     1621 attagcttcc ttaatcccaa caatttgaat caaattgttc ttagtaaact ccaagctgga
     1681 accaatgtaa ctcggcatgg caacacttgt aactttttta gctactgtca agacaatttg
     1741 agtaggttta ctcacatcat aagtcgttcc ggcacctgga ctttgtttca taatcgttcc
     1801 tggttcgctt tcgctggact cttcttcctc tatcttaatc aaattctcag gaaccttctt
     1861 ctgcttgagt tctgagatta cttctgtaga gttccgtcca atatagttcc ctaattgaat
     1921 cgtcgtagct tttttagcta ctgtcaaaac aatttgagtt gccttgctca agtcataggt
     1981 cgtaccttct ggtagacttt gcttcaggac cgttccagcc tcactctcat tcgactcttc
     2041 ttcctcaatt ttaatcaaat tatctggaac ttttttctct tttaattccg cgataacatc
     2101 agaagatttc cggccgacat aattactaat ttggaaggat tgtttgcctg atgagacaac
     2161 cagattgatt ttcgttcctt cttttcgacc agttccagcg ccaggatctg tacggataat
     2221 ccgcccttct tccacctttt cactagcctc tgtcttctcc tcaccaatct caaaattggc
     2281 ttttttgagc gttgccttgg cctctgcaac tgtctgacct gccacatctg gaatggcaat
     2341 ggttgcagga gttctggata gtatccaaat aagagaagct gccaccaata caaggctggc
     2401 caacaaaatc aggtaacgca tcttaaatct atgttttttc ggtgcttgtg gttggtaagt
     2461 ttcctctgtc acagcctggc ttgggttttt gattgatttg tgttctgtct gcgcttgaac
     2521 cttaggaata gatgtcaagg tactctgaga aaccttcggc aaggtcttgg tatctgcctt
     2581 gctcgtttca tcaaagatta acttactttc atttctacga ttgtaggaca agctactaga
     2641 caagtccaca tacatctctg aaaccgagcg gtagcgattg gtcaactttt tagcagttgc
     2701 cttgataata acattttcta aagcctgagg tacagatgga ttttctgcaa taacggacgg
     2761 caggggtttc tggaaatgct ggagggcaat ggtcaccgcg ctatccccgt cataagggat
     2821 atggcctgtc aacatctcat agaaaataat ccccatggca tagatatcac tctgcacagt
     2881 cgccttcgaa ccacgcgcct gctctggtga caagtaatga actgagccca acatcgagtt
     2941 agtctgggtc agacttgtct ctgcaaaggc tacagcaatc ccaaagtctg tgaccttggc
     3001 agtcccatct ggtgtcaaaa ggatattttg aggtttcaag tccctgtgaa caattcctcg
     3061 agtatgggcc aagcgcatag ccaagagaat ttgtcccatg atacggactg cttcttcatt
     3121 agaaagagga taatgttcct tgatatagcg tttgaggtcc agtccagcca catactccat
     3181 agctaggtac tgttgaccgt cttcctcgcc aatatctgtt atccgaacga tatgaggatg
     3241 gtctagatct gccatagctc tcgcttcacg ctgaaaacga gctacagcta tcgggtccgt
     3301 ctggtagttg gtcctcagaa ccttcactgc cacttcttcc ccatctaaga ttaagtcttt
     3361 ggctaggtag acatccgcca tgcctcctcg accaatctgt ttgacaatcc gatagcgtcc
     3421 ggcaaaaatc ttgccgattt ggatcattct gcatcctcct cgttcataaa aacaagggca
     3481 accgtaatgt tgtctaaacc tcctgcattg ttagcaaaac gaacaagtgt ctccgtttta
     3541 tctgctaaag gaatatcact ggttacaata tcacgaatct cactgcctga aatcatgttg
     3601 gtcaagccgt cactattgag caagagatag tcacctgact caaggataac tgtcccaaaa
     3661 tcaggctgaa tttcatcttt ttgcccaata gactgggtga taatattttt ttgcggatga
     3721 gcttctgcct cttctggtgt caattgacca gccttgagca attcattaac caaggaatga
     3781 tcgctcgtca actgatggta ttcttctcca cgaatcaagc cgatacgcga atcaccaata
     3841 tgagcataga tagcctgatt atcaataata gcaaggactt ccaaagtagt tcccatgcct
     3901 ctgtaagctt catcctgacc aagctggtga atcttttgat tttcaatttc taggtaatgg
     3961 gcgaaccatt cacgcacttc attgactgta tcgatctggg tatcaaccca agctacaccc
     4021 aggtctgtga ccgccatttc actagcgata ttccctgcac gatgacctcc catcccatca
     4081 gctaaaataa tcatggtacg tccagctcta ttgacatagt ggttgacata gtcttggtta
     4141 tttgttcgtt tctgaccaac atctgttaat aatgaaattt ccatgtgtca gttccttcct
     4201 aatccgatat cttgcgaaat tgactgatga agaatccatc acttccatac aattcaggtg
     4261 taatgaggat acagccgtct ttcatgatat ccttacattc atgttctagt tttacctgct
     4321 cgaactcggg atgactctct aaaaaggcct taacgacttg aaaattctcc tctgagacga
     4381 tagtgcaggt gctataagtt attataccac ctttgcctag tatttgacaa acactaccta
     4441 atatttctaa ctgaatttcc tgcaaggacg cgaaatctgc cgtttcttta ttgtatttga
     4501 tatctggttt tcggcgcaaa agaccgattc ctgaacaagg agcatccacc aaaatcttat
     4561 caaaggaatc ctggtcaaaa aactcatgca cctttctggc atccaatttt tgagtttgaa
     4621 cccgatcttc aactcccaga cgttgggcat tttcttgaat taaatccaac ttgtggtcgt
     4681 acaagtccag agcagtaacc tgacctgtcg taagataaga ggctatatgg gctgttttcc
     4741 cacctggagc cgcacaggca tcaagcactc gctcatcacc ttgtaaatca agcgtcggag
     4801 caaccaactg actggactcg tcttggatgg taatggctcc atccgcaaac aaattatgcc
     4861 ctgcaaaatg cccctgctcc ttaaccagac cagtggttgc taaaagggaa ttattcgcct
     4921 ccaacaaggc ttggatttcc tcttttcgac ttaggtctgt tacacgaata ctggctttgt
     4981 ttcgcactaa caggctttca aagatggctt ttgctctctc ctctccgtat tcttccttga
     5041 gtttggcaac tagccaaact gggagagaat aggcaatgga gtcacgcttg ttttttcgct
     5101 tgatgctagc aatatctggc cagccttcac gcaagatacg gcgaaggaca gcgttgacca
     5161 atttttcact gcctttttta cggagtttgg ccaattccac tgcttcattg accacagcat
     5221 gatctggaat cttgtccaaa tagcggagtt ggtaggcact catgagaaga aggacataga
     5281 gccagctgtc taactggtct ctgtcttcga taaagtggga taggtaccat tccagagtca
     5341 gtttacgggc taccgttcca tagactagct cggtcactaa gcccttgtct gctgcagaga
     5401 gctgactccc cttgaggtgt ttatttaagg caatatttga atatgcttga ttcacaaaaa
     5461 catcctctag cactgctaga gctaaacttc tagccgtttc tactttagtc accaaatcgt
     5521 tctcctacag tcaatgtacg tccaactcca ttgaggaagg aagcaatgtc catcttaggc
     5581 ttaccagctg gctgcacttg tttgagggat agagcccctt cagccgttgc gacaatcaat
     5641 tctttcttgc cgatagagag aatctcacct ggatttccct gaccttctac tggtagggct
     5701 tcataaatct taaagcggtc gcccttaagg aaagtatggg caacaggcca ggggttcatt
     5761 ccacgaattt ggttaaagag ttgacgattg gttttgttcc agtccagttt ttcttcctct
     5821 ggctttatat ttggagagaa ggtaacctga ctcgtatcct gcggttcagg tttgatatca
     5881 ccagcaatat aggcaggcag agtgtccaaa agcaaatcac gaccaactag cgccaatttt
     5941 tcaaacaagg tgccaacatt gtcctcatct gtgatcggaa tgctgcgacg agaaatcata
     6001 tctcctgcat ccatttcctt aaccatttcc atgatggtca caccagcttc ctcatcccct
     6061 tgaatcaagg cataatggat aggcgcacca ccacggtgtc taggaaggag ggaggcatga
     6121 acgttgacag caaagtccat gctatcaagg agtttgcttg ggagaaactg cccaaaagca
     6181 gcagtcacaa ttccatctgc tcctagcttc ataagttctt ccatctctgg acttccagat
     6241 aatttttcag gttggtagat agatagtcct gcttccttgg cagcctgctt gactggggtt
     6301 tcttggataa cttttttacg accaacagca cggtctggct gggtcacaac ggctagaatt
     6361 tcgtaacggt catctgtcaa aagtcctttt aagactgttg ctgaaaagtc gggggtcccc
     6421 ataaagatta gttttgtcat atcttctcct tcttataaaa attgctgcgg ctcatggtca
     6481 atgctgagac ggagctcact attttcccgt tcttgagtca aggccaagac ctggttgagg
     6541 gtcggcccca gctcatcttc taaacggtat ttaattaaaa tctggtaatg atagaggttg
     6601 tgggtacggg caatcggttt tggcgttggc cccagaatgg gactggtctc tgacaagcct
     6661 gaccgcaaaa tgttcatgac ttcataggca cgtttgaaaa cctcttcttc tttcttgtga
     6721 gaaagggtaa taccaatcgt gaaatagtaa ggtggatagc cgagttgtcg tctgattccc
     6781 atttcatagg cataaaagcc ttcgtaatct tgatccttgg caaatcgaat agcatagtgc
     6841 tgcgaattgt aggactgtat caagacttga cctgcttttt cagcccgacc tgctcgacct
     6901 gccacctgag tcaagagctg gaaggttctc tcagaagaac ggaaatcagg cagattcaag
     6961 gccgtatccg catttagaac tccgactagg gtaacattgg gaaaatccaa accctttgca
     7021 atcatctgag taccaagtaa aatatccgct tcccctcgcc caaactggtc aagcaaggct
     7081 tggtgactgc ctttctttcg agtcgtatcc acatccatcc tcaaaatgcg agcttgggga
     7141 aagagttctg ctagctcatc ataagccttc tgagttcccg tcccatagta acgaatactg
     7201 cggctcttac agttaggaca gacctgagga atatccttcg agaaaccaca ataatggcag
     7261 ttcatagtct tggtatccat atgcaaggtc agagaaatat cgcagttggg acaagtatcc
     7321 accgtcccac actcccgaca catgacaaag ctagaataac cacggcgatt gagcatgaga
     7381 accacctgct cttttttaac cagacggtct tggatagcct ctagcaaagg aggcgtaaag
     7441 tttgacgtct cattttgtcc gatatagtct cgaaagtcaa tcacttgaac ctcagggatt
     7501 gtagccaaag gattggcacg ttgggttaga cgtaagtgtt gatagacgcc tttgccagca
     7561 cgtgcccggc tctctaagct cggcgttgca gatccaagta ccagagttgc ttgattatac
     7621 tgagcccgta aaatagctac ctctctggca tggtaacggg gattgctgtc ctgcttataa
     7681 gccgcttcat gctcttcatc aataatcatg acacccagat ttttcagagg agcaaagata
     7741 gcagatctgg caccaacaac aacttgggca tcgccacgct ccaccttgcg ccattcatca
     7801 tacttttcgc cattggataa tcctgagtga agaatggcta ccttgtcccc aaaacgtgct
     7861 ataaaacgct cggtcatctg aggagtcaag gaaatctcag gtaccagcaa aatagctgtc
     7921 ttacccttat ccagggcacc ttggataatc tgcaagtaaa cctcggtctt cccacttcct
     7981 gtaatccctt gaagtagaaa gggaggttga gaactgccaa tagaactcac aaccgcatca
     8041 cgcgcctgtc tttgttctgg atttaactcc aaaggtctac ttgcttcaat tccttcaaaa
     8101 taagcagccg agcgttgaac ttccttttgg actatggtaa cagtaccttg atccacaaag
     8161 aagttgactt gctctcgcga gtaggactct aacaagctag ccaaggaagc gctctctgga
     8221 tgagacagca gataatctct cagttccaac tttttcttgg cacgtgtaga aatctcaaca
     8281 ccttctaatt gggcatggtc aacctcatac caagactggg tcttgacctt cttttgatcg
     8341 actgcctgat attccagacc aagcaggcct tttctagtca aacgcatcat ttcagcttgc
     8401 ttggcaaggt ctagtgaaga aaaggctagc gaatcttctg aaccaaacag gcgtactcgt
     8461 tcttcctgac tcaagccttc cagaggatag agaatcttgt catagctaga attcagaaac
     8521 cctggaagca tggccttgag gatagagatt ttgtaggaga agacagattt gcgtaactcc
     8581 tcagccagcc agagttgttc tggcgtgaga acaggagaaa aatccagcac ctctgcaata
     8641 tcttttaaat cttgctccat ctcttctcca tctgattggg acttcaaacc aagaacaatc
     8701 ccttgaatca ggcgattacc cttaccaaaa ggcacatgaa cccgcatccc aacttccagc
     8761 attccctcaa attcctccgg aatcctgtaa ctatagggct ggtccgtctg catcaagggc
     8821 acatctacga taatcttagc tagggccatc ttctcacctc ctccttgtca gtacattctt
     8881 gcaatagaaa aaataagatt gagtcccccc aaccttaaat tttttcacca tcttcttttt
     8941 ctttagcaat ttgctctttg attttctttt cttcttcttc tttgcggcgt ttttcttctt
     9001 cgatacggcg acgcactgct tcacgttttc cttctggatc tgggtgaatt gtaacgtttc
     9061 ctgattcgat ttcttctaaa gcgcgaagag ttgatttttc agacttgaaa ccttgagttg
     9121 ctggggcacc tgcttccaat tcgtgggcac gttttgcttc caagattacg agtgaatatt
     9181 ttgaaggaac cttgtcgagc aaggtatcaa tagagggttt taacatcatt tgcttgtacc
     9241 tattttctaa attttatcgg gtagttggag attttggtaa catctcctga tagtgaccaa
     9301 tgacacgatc cacacagaag tgttctgctt caatcacaca tttgacacgt tcagcagcta
     9361 ggggcacctg atcgttgaca atcgcataat catactcacg catgagggca atttcttcct
     9421 tggccttttc gattcgttgg gcaatcactt ctgcactatc tgttccacga cctaccaagc
     9481 gatcttgcaa ttcatccaaa tctggtggtg tcaggaagat aaagacagca tctggaacct
     9541 ttttcttgac ctgaagagca ccctgaactt caatttcaag gaaaacatcg attcccttgt
     9601 ccaaggtttc attgacatag gtcagaggag ttccatagta gttgccgaca tattctgcgt
     9661 attccaacat ctgtccttga cgaatcagct cttcaaattc ttcacgagta cggaagaaat
     9721 agtcaacacc gtccacttct ccaggacgtt gtgcgcgtgt cgtcatcgat acagaatatt
     9781 gaaattggtt ttcagaactc tcaaaaatct ctcttctaac cgttcctttt ccaacccctg
     9841 aaggaccaga aaaaacgatt agtaagcctc ggtctgccat tgtgtctcct tttagtcaat
     9901 ctgtgaaata acatttctct agaataatgg caaaaagcca gattatcctt tacagtcttt
     9961 ctatctagtg taacaaaaaa gcagtaattt ttcaactgct ctttcttatt tatttagcat
    10021 aatctactgc acgaagctcg cgaatcacgg ttaccttgat atttcctgga taatcgagat
    10081 tgttttcaat tttcttacga actttgtgag ccaagattgt gactttgtcg tccttgattt
    10141 ttcctggatt gaccatgata cgaatttcac gtcctgcttg aagggcaaag ctagtttgca
    10201 ctccttcaaa gccgttagca atttcttcca aatcatggag acgcttgatg tagctttcaa
    10261 gagactcact acgagcacct ggacgggctg cgctcaaggc atctgctgca gcgacgataa
    10321 ctgctatcac gctctcagct tcaacatctc cgtggtgact agcaatcgta ttcaccacaa
    10381 ctgggggttc cttgtactta cgggccaatt ccataccgat ttcaacgtgg ctaccttcaa
    10441 cctcatggtc aatggctttc ccgatatcgt gaaggaatcc agcacgacgg gcaagagccg
    10501 cattttcacc aagttcgctc gccatgatac cagccaactt agcaacctca atcgaatggc
    10561 gcaaaacatt ttgtccatat gaagtacgga actgcaaacg tcccataatc ttcatcaagt
    10621 ctggatgaag gtttggcgca ccaatttcat aggcagcagc ctcaccgtat tcacgaatct
    10681 tattgtcaat ctcttgacgg tttttctcaa ccaactcttc gatacgagct ggatgtatac
    10741 gaccatcttt gagcaacatt tccatagtca tacgggcaat ctcacgacga atcggatcaa
    10801 atcctgacaa ggtcaccact tctggtgtat cgtcgataat cacatcgacc cctgtcaaac
    10861 tttcaaaggt acgaatgtta cgaccttcac gaccaataat gcgtcccttc atagtatcgt
    10921 ctggcagatg aactgttgag tttgttgact ccgctacata ttcaccagcg atacgttgca
    10981 tagcttgaac caagatgtcc ttggccattt tgtcagaacg ttccttgacc tcttgctcag
    11041 cttcgcgaat gcgactggca atctccctgg tcaagttttc ctctgtctga gccaagataa
    11101 tatctcgtgc ttctgcctga gacagagcac caatacgctc tagttctgct tctttttgtc
    11161 tttcgacttc ctctaattgc tcttcacgcg catcaaggtt tttcgctcta tcagaaatac
    11221 tttgttcttt ttgttcaagt gtttgttctt tactcgtcaa attgtcgtcc ttacggtcaa
    11281 ggctagtagc tctctctgtc aaacgacttt cgatttgttt gagttcttga cgttctgatt
    11341 tgaattcagc gtccacttct tcacggtatt ttctggcttc ttctttggcc tccaatagtg
    11401 cttctttttt aagagacttg ctttcacgtt tggcttcatt aacaagtaaa tccgcttcac
    11461 gctcagcttg tccacgtaaa ttagttgctt cttgttcagc atttaaaagc atcaactctg
    11521 cagcttcctg agatgatttc atcttagctg agatgctgac atatccaatg actaaaccaa
    11581 tgatgacggc aaaaacagca atcgcaagcg acatgatttc catgttttta cctcatttta
    11641 ttgttattcc gaatgacata cattctttta cattctacca taaaaaagtg attttcacaa
    11701 acctaaaata gaatatgttt tggggaattt ggaacacatt taccaaaata aacttgttgt
    11761 ttagaaatag tagtttagta gagacttgag aaaaagccta ctttgcagta gacttagtaa
    11821 tgatctttaa aggacaagaa agccacgcta tctccatcca tcatataaat caagcgattt
    11881 tctgcatcaa tacgccgtga ccaggctcct tggtaatcat atttgagtgg ctctggtttt
    11941 cctattcctg taaatggatc gcgttgaata tccttgatta atttattgat tctttttagt
    12001 gtttttttat cttggttttg tcagtagcaa taatctgccc aggcatcttc tgtaaacttg
    12061 agtagcattc atcactcctc aatcacatgg acctgagtgc ttccagcacg gacttgagcc
    12121 attcctcgca aaaccttgtc tgataactcc ttattttggg cgattctcag ggtttcctga
    12181 atactgtccc attcgctctt tgaaagaact acaatgtcct catctggatt tttattgacc
    12241 accgtcaaag gctcaaattc atcatttacc ttcttcatgt agtcctttaa atgatttcgg
    12301 aatgttgagt aaaggactgc ttccataacc atacctcgtt ttagctcttt tccactatta
    12361 tacacgaaaa gaaagaaatt gtcaggaact tgtacaagat tttcttttct atctatttat
    12421 actcaatgaa aatcaaagag caaactagga aactagccgc aggctgtact tgagtacggc
    12481 aaggcgacgt tgacgcgatt tgaatttgat tttcgaagag tattattcgt aaaaaatctc
    12541 aaaaagccta cctttcggta gacttagttt gtttctattc taatcggcac tcttccaaaa
    12601 ttttgctctg ctatacttgg cttccctagt tggtaaatct ggtctgcttt ttgggtcata
    12661 gcatcccaag gttctttgcc aattcggctg actagattga cctgtccttt cagagacttg
    12721 agatgttgcc tgactttttc agtaaatcca aggacatgaa tggcttctgg caagacattt
    12781 tctctagcct gtaccaaaat ataggtcaat aggcgtctga cacgcgcctt ggtgtaacgt
    12841 ttggtagtca ctaactcgac caattcttcc acagactggg ctgttttaat agcttcttta
    12901 atgcgcacag ccatttcttg attgacctga tagatggtgg ttaggtcggg atttgacaag
    12961 atttgatagc ggagcaaggg aaaatagtct tcccagatca ccttactggc ctgctcaaat
    13021 agggcaacag aaggcataaa acgttctaag aaatcttggt ccttctgatg ttgacggagg
    13081 gctgtcgccg aggcaaagtc cacatcttta ttcacagaat ggtaacctgc cccctgacgc
    13141 tgaatcggat gcagcttgat atttcgtcct gcaaccgcct tggcataggc cagagcaaga
    13201 acatgattgg gggtattacc tgaaaaatca agaccagcaa attccttcca catagcttgg
    13261 gttttctggg gataggaaag ggaatcaggc agatttttca caaatttctc catctcagca
    13321 cctttctctg tgtataagtc agcgattttc tggtaatcca gaacttcctc tgtcccaaaa
    13381 actagactat caatgcccaa gcgatccaag atatccacag ctccttgacc aaagaaatca
    13441 gctgcctgaa cactgactaa aaagggcaat tccactacca agtctgcgcc attttccagc
    13501 gccatctggg cccttgtcca cttatccaca atagcaggct ctccacgctg catgaaattc
    13561 cctgacatgg caacaatttt cagtccctct gcctgatcca gcaggtattt atggccatta
    13621 tgaaaaggat tgaactccgc gataatacct gttatggtca tgctaatctc ctacttctgc
    13681 gccacaaaaa accaacgggt gctagtttct gttggctcct tatcctcaaa gtctgcatag
    13741 agtttgaagg acttaaatcc agcctgttcc agcaagatat cataggtcaa gatctcatag
    13801 gtcctctcct catgtacttc atcgtggcga ctaaaggaac cgtcagcctc cttgataaag
    13861 aaagtcagct catgcacgat ggagtgagga acttcgtcct catatgtatc ccaaagcatg
    13921 gcaaaatctt ccgcattttc atggtaggaa tagccaggga atacttcatc tgtctggtag
    13981 gtcgagtgca cgtcaaagat gaaaactccc tcttcattca gcgcattgta cacgtcctta
    14041 aagacgtccc ctacttccac ctcatcctgc atatagcaga tagagtccga ataacacgtg
    14101 acaaaatcgt atttccctgc cttggacaaa ttcagcatat taccttctat aaaagcaatc
    14161 ttttgcttgg ctgaagttgc tctcttctcc gcaatcttca acatatccgc actcaagtca
    14221 agtccagtca catcaaaacc agcctgagaa aagcgcactg attgaattcc tgtcccacaa
    14281 gccaattcca agagtttctt tctctccttg gtcttaggca aatgacgcag agaaaaattc
    14341 gtccatttgt cgtataaact atcgtccatg accgcatcat agaccgccgc aaaggtttca
    14401 taagtcgcca taaaacatga taccaagtcc gcccgtaatt cgatagaaaa ttaggagcct
    14461 tacgatggag ccgagctcca aggaaggcta tctattttcc gagaattaca ggacgggttc
    14521 aaatcctttc taagatacaa agagccttaa aagcaaagag tacataggaa actttcttcc
    14581 ctatcgtcag atacaaagaa agttactttt tatctcagct tttagctcgt gttcagtttc
    14641 gaaatgaaac aaacacgagg ccctttacct ttctatcaat ttttctaaaa taagcaaaga
    14701 aacccagttg actacaactg agttcatctt ctaagcaaga gcttctgaaa tatctactga
    14761 attcgcctca tgccatagct tctctagatt ataatgggca cgcatttctt ctgaaaagat
    14821 atgcacgaca acagcaccaa ggtccagtaa gacccagcct ccagctgcat cgccttcgac
    14881 atggctacct ttaaagcctg cttgagctac tttttcacgg atattagctg cgatagcgtc
    14941 caactgacgg ctattcattg agctagtgat gacaaagtag tccgtcacac tagtcaaatc
    15001 ttgtacatca agtgcgagga tatcctccgc acgtttctca tcagccgctt tcacgactag
    15061 ttctagtaat tctttttcgt tcatttaatc ctctttttag aaaatatgtt tgtaatctag
    15121 aacatctgca aagcgctcct cccaaatgtc ctcataaaat tcattaatcg tttctgctgg
    15181 aatgtcatcc ccatcaaagg ttgtgacagc accttctgga acaataagct gatagccata
    15241 ttcaaaggca accttgacag aggtatccac acaatattct gtctgcatac cacataaaac
    15301 taatttttca atcccctgct tatccaagta ttcttttaag ccagtttctt tgaaaatact
    15361 gttatacttc ttctgaaaga ccttttcagc aggttttcga tttaaaagcg cagataactg
    15421 ccaatcttct gatgtttgag cttcagagtt ctcaatatgt tgaacataga taatttcaat
    15481 attcttgctt ctagcctggt tttgtaaata agaaattttt cccaatagac tttttgtctg
    15541 gaacccagtt tctactaaaa tattctgaac atcaatgatt ataaaagccg tcttcattta
    15601 gttctctttc aaatagtgca caaaggcgtt ataggtttca agggtttggg gatagatggg
    15661 gaatccctga tgagctagat actccacggt acgagctgtt tcgtaggcca ccgccttatt
    15721 gagcgataga tttgcaatct cacgcgccac atctactcca ggaaaggctc gattgtgctc
    15781 gatatagtct gcgacgtaga tgaccttatc taggtctgtc atttgaccag caccgactgt
    15841 atggacttca atggctcgca ggatttctga atcatgcaaa tccaaatctt cctgaatttt
    15901 gtaaattccg accataccat gccagacatt attgccccag tttttgaggt cagggtctag
    15961 ctggtaacgg tcaatcaagg ctagaaattc ctgatttgac aactttttag catagtcatg
    16021 aagaagacct gctagacttg ctttctcaac atctacacca aagcgctgag ctaattccat
    16081 agcggcacgc tccacaccta gacaatgggt tagacgtttc tcaggtagaa actctgccat
    16141 tttttccaac aaggcctcac gggagcagtt gatatagtct tgataggaca tcagtagagc
    16201 ccctccttct cgatgtagtc tagcactggc tgaggtagga gaaagttggg tttccgacct
    16261 tgggcaagga agtcccgcac catgctggac gagatatcca tgagcggtac gtccacccag
    16321 ataactggat aggaagtccc taccttgtag cgtggacgct gaacccccac aaactgaacc
    16381 atgtcaacca gttcatcaat tcggtaccac ttaggcagat agtcaaccat gtcggcaccg
    16441 atgataaagt aataatccgt atctggattc ttctctgtca aaatcttcat ggtgtcgtag
    16501 gtgtaggaaa tacccttgcg ctccaactca atggtttcaa tgactaggcc gtcaattccc
    16561 tcaattgcca actcaagcat cttgagacga tggtgttcag ggatggtttc ctttttatca
    16621 acgtgaggag gttggtattc aggcatgaga agaacttgat ccagtcccaa ctgttgccgt
    16681 acttgatccg caacaatgag atgggcattg tgaacagggt taaaattccc ccctaaaatc
    16741 ccaacttgtt tgcgtttttt ctccttgatt tctggctcca actctacctt ggtaaaggga
    16801 gtcaatagtt cgattgtcat aggctagtcc cctttatttc tctataaaaa cagttatttg
    16861 gagtttcggt cttagatttc tttgactttc ttagaaatct tgcgattttc tttcttgcta
    16921 gattgcttaa acaaaatcaa gatgcgtcct attttttgga ctgtatccac accgatttct
    16981 tcttccaaaa tttcagctac ttcgtggatg ttttcatctg tgttttgtaa gagagtaacc
    17041 ttgattaatt cacgcgcatc aagagcttga cggacgctgg ttttgatttg gtcgttgagt
    17101 ccatttttcc cgatttggat gataggtttg agggtgtgtg cctggctgtt gaggaaggca
    17161 cgttgttttg atgctaatga cataattttc ttccttgttt tttgatagtt attttaggtg
    17221 gtgagggacg gtcggaacta attttccaaa gatttcatct ttgaaaaatg gatttcctga
    17281 cctcacaatt gagccttggt ctcaattgtg ccccttgcca atctacagat tggcaatcac
    17341 accacggcaa taactatcgc tatatgagct cactttgttc gctcagcgat tttgttttaa
    17401 ataattgctt ttcgtgtggc gacggcgacg ccttctggtg cccagacggc gacttttgct
    17461 gtgcctgtta cacgaatcca gcctaggcct gaaatgacta ggtctgtctt atctttaatg
    17521 gtaaagacat gctggactag ccttgggaaa tcttcttttt ccttgctatt tggtggtgtc
    17581 agaagagttc ccaggtgctt atcgtagaaa gcactagctc cttcaagctt gctacgatgg
    17641 agtttgagtt cattatcaaa gaaagcagta aatccttgct tttctcctgc tataaagtca
    17701 aagcgtccca aaccacctaa aaatagggtt tgctcaggat taagctgata ggtcttaggc
    17761 ttgatttcct ttttaggact gacatacttg aggtttttgg ccgtcaagta gtgagccatc
    17821 tggtggcggt ggataattcc cggcgtatcg taaatataag atccgtcgtc aagcggaatc
    17881 tctattttgt ccaaggttgt ccctgggaag cgtgaagtag tgatgacatt ctgatcaccc
    17941 gtgatttctt ggataatagc attgattaga gttgattttc caacgttggt cacaccgacc
    18001 acatagacat cgcggccctt acggtagtgt tcaatcttat caatgacttc cttaatggca
    18061 tgtttatttt gtgctgaagt taggaccaca tcgactggac gaagaccttc ttcatgggca
    18121 cgtttcatga gccactggct aatcttacca gacttaactg acttaggaag gatatctttt
    18181 ttatttccta ccaagaggac atcattgccc gagacgaaac gtggtaaacc tgggatgaca
    18241 gatccattaa aatcaaagat atcaatgaca ttgaccacta aggcatcact gtctcccacc
    18301 tcgtgcaaga gcttgaggaa atcatcgttc gtcaactgga catctgtgat ttcattgtag
    18361 tggcggagac ggaaacagcg ttggcaatag acttcgccag tctccaaacc tttttcaagt
    18421 gccgactggg gggtaaaacc aagaccagct ttatctgtcg tctgaatggt tgctccacaa
    18481 ccaatacaga gaatttcttc catagttaaa ttcctttttt atatgtaatc ggtccgtact
    18541 tttcagtgat ttttctcata acacgacgct cacgagttcg gttaatctgc gttttgattg
    18601 agtcatgttg gaccaagggt ttgactaaaa ttgaccgaat ccctgcacgg tgggctgctc
    18661 gtatatctgt catgagctgg tcgccaacca tgaccacttc ctttttgtca tagtggaatt
    18721 ccttcatggc acggtcaata ccaaatgtga agggcttcaa ggcccagtaa acgtaatcaa
    18781 tcccaaattt ctcaactgct cgttgaacgc gttttttggt gttatttgac actacgataa
    18841 tgccaatacc cgcgtcccga aggtcatgta gccattgctt catctctggc gttccatcag
    18901 ggttgttcca agcaatgagg gtattatcca aatcgaccaa aacagccttg attccctgcg
    18961 cctgcaggct tgggactgtc agatcataga ctgcttccac agcaaaatct ggtatataat
    19021 tttcaatcgc cattctggct ccttttctta actttttttc gcaattttcc ttagtaacaa
    19081 ggataaaaca atccacaaac ctgcactagc caaactgata tagagccaag catggggctc
    19141 atctgttaaa ggtaagggaa cattcattcc gaaaaagcct gtcacgactg ccaaaacagc
    19201 tagcaagact gaaatgatag tcaaggttgt caaattgtca ttcagattat tgtttagaat
    19261 attgttgtaa gaggctgaaa gctgctgtaa aatctgagag attaggtctg tcatggatac
    19321 cagctgatga gcctcaatca tggcatcatc aaactgttct ctctcaatct catcaaaact
    19381 acgatacaag gcatgacctt gaatatgctc taacaaaatc cgattttgtt tggcagctgc
    19441 cgtcagataa accataccag tctccaaatc agacagggca aagaggtttt tcttggtagt
    19501 tcgctggcgc aagaggtcat tgacctcatc cctactcttg tccatctgct caatgacagg
    19561 atagtaggca ttgctgatga tttccagact ggcaaagaga aacttataaa tcgaaagcgt
    19621 gtcatggctc tccagataac gagtcatctg ttcaatgaca taggcgttct tggtattact
    19681 aatggtaatc aggcgacgat gctcgacgat aaaggtcatg ggaaaagtct catagtaggc
    19741 cttgtccttt tttacgtcta ggacattata gataaaggta accgtcccac tttcacggtg
    19801 gtagtccatg tgggcgcgct cgtttctatc cagtgcgtat tcaatggttt ccttgtccaa
    19861 accgtaaatt tcagaaaggt cttctagttt attcaacttt cctaggtcta ggtctatcca
    19921 ggtacaacca tggcccaact gcttttctaa aaccatcttt tctccttatt aaactccctc
    19981 tattgtacca caaattactt aaaataacag gtctagtctg tgcgtgagaa attgctaaca
    20041 actgtgatat ttcggttagg gacaaagtga agggcttgct cctcgctacg aagctgtgtc
    20101 gtacgaattc ccacactgac aaccttaccc gatacagtaa tcggtccatt tgtcagaacg
    20161 acctcatctc ccacatccag ttgacgttca aagaggatga aaaagccatt gatgacatca
    20221 gacagaaagc cttgggctcc cataccaatc gctaccccag caataccagc tccagccagc
    20281 aaactagaaa ctggcaaacc taaaatcgac aaaatgcagt agagtaaaaa gaaatatagc
    20341 gtataattaa acacattttc tagtaaacgt gagatggttt tttggcgtcc gacatcatga
    20401 cgagacattt ttagagaagg tttgacaatt ctctgcacca tggtatgaag cattttttta
    20461 gcaatataaa atacaatcaa aagcagtaaa agagaaatga ccttggttag aatattctcg
    20521 ataatggttg tcacatctag cttttcaata taagcctgaa taaatttttg catataaaac
    20581 tcctttattt cattatacca tattttcatc agtctcattc tccataaata ttcaaaaaat
    20641 agacagaaaa ttcttgattt tgtctatcat ttatactata atcataatca ctacacaaaa
    20701 aggagattat tatgaaaaga atcattcatg cttggaataa ggcaagcctt gtcaagcgta
    20761 tcttgattgg tatgctttgt ggggaatcct aggactgacc cttcctaatc tctcagggat
    20821 tgggctactc ggggatttat tcgttggagg tctaaaagct gttgctccta tcctagtctt
    20881 tgctctcgtt gccaatgccc tttcccaaca tcaaaaggga caagatagca atatgaaaac
    20941 tgttgttttc ttgtatatcc tatgataggg actttcgccg ctgctcttgt agctgtacta
    21001 gcaagtttca tcgtccctat tgaaattacc ctaaatagtg ccaatactga aattgcacca
    21061 ccagatggga ttgggcaggt cctcagcaac ctcttgctca aactggttga cagcccagtc
    21121 aacgccctgc ttactgctaa ctatattgga atcttatctt gggcagtcat ttttggaatc
    21181 gctatgagag aagccagtaa aaatagtaaa gaattgctaa aaactatcgc tgacgtgact
    21241 tctaaaattg tcgaatggat catcaatctg actccatttg gaatccttgg tcttgttttt
    21301 aaaaccattt ctgacaaggg agtcggaagg cttgccaact acggtatttt attggttcta
    21361 ttagtaacga ctatgctttt tgttgcccct gtggtcaacc ctttgattgc cttcttcttt
    21421 atgagacgca atccttaccc tctagtttgg aactgcctcc gtgtcagcgg tgtgacagcc
    21481 tttttcactc gtagttctgc ggctaacatt cctgtcaata tgaaactctg ccatgacctt
    21541 ggactcaacc cagataccta ttctgtttct atcccactcg gttctactat caatatggct
    21601 ggagtagcga ttaccattaa ccttttgacc cttgttacag ttaacactct tggaattcct
    21661 gttgactttg ccacagcctt tgtcctcagt gtggtagcag ctatctcagc ctgtggtgct
    21721 tcaggtattg ccggaggttc cctccttctt atcccagttg cttgtagcct tttcggtatt
    21781 tctaacgata ttgccataca aattgttggg gttggttttg tgattggtgt catccaagac
    21841 tcatgtgaaa cagcccttaa ctcttctaca gatgtcctct ttaccgccgt tgccgaatac
    21901 gcagcaaccc gtaaaaaata actcatcaag gcaagcctgc tcatgtcttg tcttttacgc
    21961 ttttattcta acttattagg aaattcttat gtctattagc caacgtacga ccaagctcat
    22021 cttagctacc tgtcttgcct gcctgtttgc ttattttctc aatctttcgt cagcagtttc
    22081 ggctggaatt atcgctctct tgagcctatc tgatacgcgt agaagtactt taaaactggc
    22141 tcgcaatcgt cttttttcta tgcttctagc tctggctatc ggtgttctag cttttcactt
    22201 gagcggattt catatctgga gtctcggcct ctatctggcc ttctacgttc ctttagccta
    22261 caagatgggc tgggaaattg gcatcacacc aagcacggtt ttggttagcc atctcttggt
    22321 tcaagagtca acctctccag acctcctagt caacgaattc cttctctttg ctatcggtac
    22381 aggatttgcc ttgcttgtta atctctatat gccttcacga gaagaggaaa tccagcacta
    22441 ccacacgctg gtggaagaaa agttaaaaga tatcctccag cgcttcaaat actatttatc
    22501 cagaggagac ggacgcaacc gagcacagct ggtagcagaa ttagacacgc ttttgaaaga
    22561 agccctcaga ctggtctatt tggatcactc tgaccacctc tttcaccaga ccgactacca
    22621 tatccactac tttgagatga gacaacgaca aagtcgtatc ctgagaaaca tggcccaaca
    22681 gattaacact tgtcaccttg ccgccagtga aagcctgatc ttagcgcaac tcttttcaaa
    22741 aattgcaggt caactgagcc agaccaatcc tgcttctgat ttgctagatg aaattgaacg
    22801 ttatctggaa gtcttccgga accgcagtct gcccaagaca agagaagaat ttgaaacccg
    22861 cgccaccctt cttcaactcc tacgtgaagc caaaaccttc atccaagtaa aagttgattt
    22921 ttaccaaaaa tatagacagt aatactcttc aaaccacgtc agcgtcgcct tgctgtatat
    22981 atgttactga cttcgtcagt tctatccaca acctcaaaac gatgttttga gctgacttcg
    23041 tcagttctat ccacaacctc aaaacggtgt tttgagctga cttcgtcagt tctatccaca
    23101 acctcaaaac ggtgttttga gctgacttcg tcagttctat ctacaacttc aaaacggtgt
    23161 tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga gcagcctgcg
    23221 gctagcttcc tagtttgctc tttgattttc attgagtata aaaaagaaaa cttcagacca
    23281 atccacaaaa ggtgaatatc tgaagttttc ttttatttat aagtaatcac cataaaggtt
    23341 aatagtagaa caaataaagc caaactcacc aataaagtga gcaccttgac caaggtgttg
    23401 ctctgccagt agcttggttt accaatatta ctagtggcat ccatggaaaa tagttgattt
    23461 tgacggggtt gtatagttac caatacaatc aaagcaagag ataggataat agctaaaaca
    23521 attagcattt caatcattga tctacctcaa aattcccaac aaagtaaaga gcaaaccaat
    23581 cagaatcatt aagcccagta aaagtgaaaa agttttacta atcttctccc ctcgggtttc
    23641 tttttccttc ttgatgggtt tttgtttcaa ctcttccatg cgaccttcaa cgtctttgta
    23701 aaataaatct tcctctgaca tgttagcctc ctaaaacagt ttgcattatt tcttgatatc
    23761 gcaccaagtc aacataattt gcatgttggc cttgtttgcc aagtgcctga cgcatttgat
    23821 caacatctga aagggccaat ttaatggtct caaccaaggc agcaacttca ctactttcaa
    23881 atagatgttc tggagcgata taaagtctat tgtgaaccgt ttggttaaat ccaagaatca
    23941 agagattgtg ctcaaaggcc tgacgcactg cctgcaacaa ctcattgctg tgattgatat
    24001 ccaagtaaat atccgacagt tgatacagct cctgaatctt ctgtggacta gcattctggt
    24061 aaaggaccac attaggatag cgaagcatgt ctaagagctt agaagacatc tctgtcactg
    24121 ctgcgatacg gaaggtaaca tcaggcaagg cttctacgat tgcttctact tgctcaatct
    24181 gatctgaatt ggtcaagatt aaggcatctc gtcttaggaa attatcacgt ttgaactggt
    24241 aatgataacc caagtgcaca aactgatcat ggtatttctc gtcagttaac tctaaagcgc
    24301 gctcataagt cgccttattt ggaatgatga tcttcttagt acgcacatta tcactttcca
    24361 aaatcaactg catattacct ggaatggcat catagagagg ttcctgccat accaagacat
    24421 ccgagccaga tttatctgga tgatggaagg aaaccaagaa aggagtcgct agagtattaa
    24481 agataagctg actggtatct atttccaaat cttgcaaaaa gaaggtgata aattcaactt
    24541 tatttgcaaa gtaacgcatg gactgaccag gcaaagtcaa taagatatca cccgtcacat
    24601 ggttttccag taaaacttgt tggccattga catcttggta aactgtcata atcggctcgc
    24661 tatctgcgct ataagtggtt ttagcaaagc aagcaccaaa gcgattgtag tggtcaacct
    24721 gacgtactcg accttctagg tctttccagt ctacctgttt aaccaagcga gcctgcattc
    24781 catcaacata atgaatgaca gccctctcct gcgtcacatc ttcaatacaa gcagactgat
    24841 tatctcctaa aatttcccaa aaatctgaaa cgggaacttg gttaaaatag agaggttttc
    24901 catcctcgta acctagataa taggtaaaag gagaaagcag accatcaggc agaaaaccat
    24961 ctgcatcgat gaccactcca agttgagaaa gaccagtagc gactagactt tcatgtaaat
    25021 ctctactttc ttgactgtaa ctatcataaa gttcaatcat ggagcacctc ctctactgtt
    25081 ttcttccact tttctaaaat ttctttggtc aagaagcctt ctgcaatttg ataagaatag
    25141 gcacgcatag cttccaaacg attttcttga tacaattgac aaatcttagc ggcataagct
    25201 tgcttgattt ggtcttctac atggtcagat gaacttggaa tcaaataacc attttgccca
    25261 tcctctataa aggtctgatt accataaggc acatcaaaac caattagagg tagacctgaa
    25321 ccaatagctt ccatcaaggt cagaccaaat ccttcgctgg tagaagccgt taagtagacc
    25381 tcatactggc tataaatctg cgaaagttcc gcatgcccct tgagttggat atagtcctct
    25441 gcctgatgat ttgcaataat ttctctaagc agagaatctt ctccaccact accatagata
    25501 tcaaaggtta gttccggtaa ctccttatga gcttcaatca cagctttcac aagccaatca
    25561 atgtgctttt ctttggcaag acgtgaagcc gtaatcaatg aaaatggttt gcgcccttga
    25621 cttgaatctg tcaaggaatc aatactgcct acaggaatgg taacaatctt tggctgatgc
    25681 tgagtatatt tggcaaattg ctcttgtaga acttcatttt gtctatcagt agacacgata
    25741 aagaagtcaa ccttatctgc attggtaaac tgatagtcat aatagttatt ccaaaggata
    25801 tagtcctcat ttgtagcatt ttcactataa tgctccgcat gaacaactac cgctagatgt
    25861 gctgtctgtg cttcctcaaa cacaacctgt ccaatacctg tctccctatc cagaataacc
    25921 aaatcagact tgttcaaatt caaagatttc ataaaggcac gcacaaaagc ttgctttcca
    25981 tagaaaatct tatccttgaa atgataaact tcttccttcc cttgattcat caaaatatca
    26041 tagactggag tcccgtcttc attgtaaaaa gttcgttggt ataagactgc aacattgtcc
    26101 ttgggagcaa aatactcgct acaataacgc gtataagaaa agtaatcctt ccgaatcagg
    26161 tttcccttaa aaacatactc ggcatgttga accaagtcct tgttctcatc aaccaaataa
    26221 caggttacaa acttatcttg gtcaaaaaag aatacacgta aaaccttgcc atttttttct
    26281 ctgtgacttt cttcaccacc aaagtaagcc aagacatcat ccactgtcac gctagtaggt
    26341 gcaattttga tatctgtgaa atgattataa agccagataa cctgattatc atcaaaacca
    26401 atattggctg ttaagtgctg aatattatcg gctaaaatca tatctgtaaa gataaactta
    26461 gaggacagat ttaatttccg aaaaacacca gcacgatagg cttgagcgta ttcaacaccg
    26521 ctactagccc aaccaattcc taaatttata ttgtaaattg tcatattttc tcctcttatg
    26581 gaaaatgagt cacgatttca ccttttggag tgacctcaac cagccccatc aggagattac
    26641 gcaccatatc cgcacggatt tgttctttca tagcttcaaa gcccgcgtag gcttcttgat
    26701 agtactctac gattggattt ttctgactag cagattgacc accgatagcc atggatagct
    26761 gttgtagata gtctacctgc tctacccagt tgtcatcaat ggctttaagc agtgaaagtc
    26821 gtaaaaactg ttcatataag tcatgttgat taagtaattc tttcttttca gaaagttctt
    26881 tatcaatcac ctgcttcata aagctacgaa ctgcagtttt gtcagttaca tctatataat
    26941 ctggaacctc tttaacatga aaactaatat tggtcacaat aaagtgaaac aataattcac
    27001 gactagcata gtgatcagcc gctacctctt ctgtatatct ctcaatgata tccacaacaa
    27061 catcctctaa gtcacgagaa ccatctatta gacgatttct ctctttatag actatatccc
    27121 gttgtatatt catactttca gcatactcca gagtctgacg acgtgctgaa cgtccagcac
    27181 tatcactggc atgctgagcc ttttcgacta gtttccggta tttacgacct ttcaatactt
    27241 ccggttgagt catatcttga acctgatagt ctttgtactt tttatgcacc caagatggac
    27301 caaatttctt gataacatca tcctctaagg atacaaaaaa tttactcata ccaggatctc
    27361 cctgacgacc agaacggcca cgaatttgta ggtcgatccg ctgactttcc atccgctcag
    27421 tcccaataac aatcaagccc ccaagctctg cgactccttt accaagcttg atatccgtac
    27481 cacgtcctgc catagaggta gccactgtca cagcccccat ctgacctgac tcggagataa
    27541 tctgagcctc acgcgccgca ttattagcat ttaggacatt atgggcaatc ccttcacgaa
    27601 acaagagaga cgaatagagt tgagacattt caactgagcc tacaaaaacg agtaaaggat
    27661 ttcccttagc atggtattgc ttgatgtact ccaaggatgc atacactttt tcaggtaaag
    27721 tgatatatag attatctgga tagtcaatcc gttgtctcgg acgattggtt ggaatgcgta
    27781 ctacagacat attgtaagtt tcaataaact ctttttccgc gaccttacct gtccctgtca
    27841 taccagatat cttattaaac atcttaaaaa gactctgata ggtgatcgag gccatagccc
    27901 gcgtctcagg agataatttg acatgttcct tggcttcaat agcctgatgg agacctcctt
    27961 gaagtttagt catttccatt agacgccctg ttcccttatc aaccagtacc atctcatttc
    28021 cacgaatgat atagtcctta tctttagtaa agagcttatg agctcgaatc gcataaacca
    28081 aatgacgagc aaaagacgca tgctcttcct tgtataaatt atcaatccct aggaaattct
    28141 cagcagactt ggccccctta gtagtgagcc aaacctcctc tttctcctct ttaaagatat
    28201 aatcctctcc ttcgaccaag gttgttacaa gtgtatcaat gatcgcatag taattagact
    28261 gaacacgagg agaacccgca ataatcagag gagtttgtgc actatcaagc aagatatcat
    28321 caatttcatc aataataaca tagttaaacg gtcgtaaaaa cttaccttct tcattcgagg
    28381 ctaggttatc atttagataa tcaaaaccta aactactatt ggttgtgtag atgatatccg
    28441 aagcatagat aagcttcttt tcttcagctt tcatttcctt ctttggatct tccgtaaatg
    28501 gtacaccaat ggtcaatcct agaaaacgat aaacttggcc catttcctcg gcatcacgct
    28561 ttgataaata ctcattagga gtcacaacca tcactccttc tcctgaaaaa gcgttcaaat
    28621 agacaggcat ggtagctgtc aaggtcttac cttcccccgt attcatctca gcaacatttc
    28681 catagtgcat gacaatagct cccatgactt gaacatcata ggggaacatc cctaaaatcc
    28741 gcttatctgc ttcacgcacc acagcaaaag cttcaaccaa aatatcgtct agactttctc
    28801 cctcggaaag acgctgacga aactctactg ttttagctac taattcttga tccgaaagag
    28861 aggacatctt gcctttcagg gcattaatct gctttaaaat ctttttcact ttcctaagct
    28921 ggaaatcttg acctaaacgt ctaaacactt ctgatctcct tgatagaaaa atgataaaaa
    28981 gttaaggact caaatccagc acttaaaaga gaaacttgat aagtataact atcttctgga
    29041 taagtaaata tgaaatcttt cgctttttct accttttttt ctaaaatatc accatagcgg
    29101 tcaaaaaaag ttatcttggt ataaactcca ttttcaggct gacaatcaaa aaccagtgat
    29161 agttgatact cctgctttct ttttaataag ggaagctgag gttgggttcg tgcagcctgg
    29221 taattgacac tagaaaacca agtctttaga atctcaccag atggcaatag aggattatac
    29281 agacgaacac ttttgtcaag gtaataagat acagttgttc catacatata agtcccacca
    29341 acttctcccc aataaataga ctgtctctgt gtaataatca tcttttctcc cttccaaaac
    29401 cagtctctaa gaccattcta taaaagtgca aaaaccaaga aatattggta tctgtatcat
    29461 cattgtgtcg tccagcagtt cctttagata aaatcttcgc acctgtatta cacagataag
    29521 acactaattg ttcataggct tgtggatcca tttcttcatc tttcatatag gataaaccaa
    29581 aggttgtctt tgaaaaattt gcttgtttaa aaattttcca aaaacgctga tccaactccg
    29641 tcatatcttg agaacttgtc ccacctgtat gatgaattaa acaatcaaaa gctaagttag
    29701 agacacccgg tgcgtccaaa cgtccacgac tagctatagt tcctaaatta gccaagggct
    29761 taccaactat gatggcatgg ggttcaaaag aagcaccata atagagagcc ggaaacgttc
    29821 ccatagaaag acctgataaa atcaaatcct tatgatcaaa gcctaaataa tcaagatagt
    29881 gagtgatcgt atcctttact tttccctcta gctcatccgt tccgagataa aaagctcccc
    29941 cctctaaacg tggatcagaa aataaaatga agggacatcc aagagttttc atcataaagt
    30001 aaccctcgaa tccttctgca ggtcgataac ctgcaaaata gacagtcaaa ggcggtttaa
    30061 aatcacctgg atggaagaaa tagtttattt catcacgctt ggaatcatgt aggatatttc
    30121 caccaagtac aaacttacca aattgttttc gactccatcg ttggtgaaga ttacctagtt
    30181 tgatagttcc acgacctctt gcttcaacag atatcgagag aaagtagtct ccgtctcgac
    30241 tatccataaa aagtgcttgc tccaagtctt tttcagatac tattacttct tcaaagaaat
    30301 catcaacaga cccactccac attttacgga ttactaaacg aaagtcacaa ttgccttcct
    30361 tctcatattc aagccacaac tcaataggga gtgttttttg caccataata ttataagccc
    30421 aataggcaag ctgggcaaaa tcttgcccaa actcaccttc caaactgaca taatccaatc
    30481 cttgataaga aatagctcct gtaaaatttg gattgacttg tatcgtcgga ggaaagagtt
    30541 tatcaccata cccaccgcca aaaagagatt tacttaaatc attgattagt tgttggggac
    30601 ttaaaaaatc aattgcttgt gcacatcgtt tttttagaaa atccacaacc tctctatcat
    30661 ttatttgtag attctggtta tagaacaaag tataaggttc aaaatatttt acataggaaa
    30721 ataagtctct ggaatactga ccatcttcta ttaaaactgc atgaaaacgg ttaatatcct
    30781 ctttttcgat tatttcacga agggtttttg atgagtttgg gtaaaaataa taccaactca
    30841 tattttcagg tatgtcatag tgattttccc aattggcaag tcctatctgt aaaatattaa
    30901 gttcctttga catttttaac ctcctctatc catttctcta attttccaag aaattgttgt
    30961 cctgtgtgct ccttaatctt atcaattgaa tatatcaagg actcattcca ctccttcaac
    31021 ctatctgtgt aataatgtgc agccttagaa aattctgtca catctgtcag caaataacca
    31081 ttttttaaat gttccacata gacggtttca actaggttga tttgaggaat tcctgcacta
    31141 atcccagcaa tctgtgtgta gagatgagga tgtctattta aatccacaat caaacggaca
    31201 aattctagtg tttttatcaa atctaactca tcattcaagt taacaaactg taagcgtaag
    31261 tcctggtgtt gattttcttc caggggattt tctgcatcac cataatcaat cgcctttccc
    31321 agattttcgg attgaatgtt ttcttggatg aaagactcaa caatcccttc aacctcattc
    31381 atttgctcct gactagcagc aaaggctcca aaaatcacct cagtatcctt attttcagcg
    31441 acaaaggaca agacttgaag cagagcttga ttatcaatcc cctgctcaaa atccagttga
    31501 aaataaatga tggattcttt cttagtttgg cttcgtccca atcgtaatcg ggtgtcaaaa
    31561 gatgataaat gataacattg atgcattcgt tcaggataca actcctgcaa caatcgtaaa
    31621 ctatcctctc tatccaccaa aatcaaatcc gatttttcaa aagttacatc taaatcccta
    31681 aaggtatctt gaggattacg tccaatgaac agactcaaca gtttaggatt agtactaggt
    31741 aaacgatcta gtaccaactg gtcatgatga gaatgagaag gaagcataaa aatatcctga
    31801 tccttcacat acgtttgcag ataattctca aaaaattctg ccaccagatc tcccatattt
    31861 tgataggtaa gcattttaaa gcgataaccc aaaattggat tgacttctac ctgtcctcct
    31921 tcttttaaac gctctctaaa ttgccaaact cccttaggat tcaaatattc ttgataggct
    31981 gcttgcccat cttcaaaaaa aataatactc gatataaacc ctcgatcatc catgatatgg
    32041 tgcatatgta tttgaccatt tggttcaaaa tactgtatat cactgatgaa gccttcaact
    32101 ccatgttcaa ccttagcaaa tttcttccca tttttttgaa cgataatcgt aaagggacta
    32161 taaataaatt cacagtcatc atcccactca atatctctaa tgcttaaaac ttgggtatgg
    32221 agattatgaa aatcttgcat aacatcaaaa acggaataag tatccgtttc taacacacca
    32281 tgtctatata aaaaataacg tagatgaggc tggtaagcta atactaatag acgagaatct
    32341 atatcttgct cttgaaagag ccggatctgg tgaaaggtat catcaaactc tagacgaaaa
    32401 tgagaaaaat accatggagt gatatctgca tgccatgttc tttctgaccc ataccaagct
    32461 ggaataaaat aatacataaa agtctcctaa atcaaaggtt tataggtctc atttagcctt
    32521 aaagccttga cctcgtctct aatcgtaaaa atcatgcctc caaacatcat aaacaaacct
    32581 ggaatcattg ccaatcgtaa taacttttca tcaaacaaaa caaaaagcat gggaccacct
    32641 gccataacca cattaaagag accacctatg actgagaaac gaaggaccaa tcgattaata
    32701 aatcgactag tatccgcacc tggataaata ccataaatgt attctccaga ttttttcata
    32761 cggtctgcaa tctcttctcc attcatcgta acaaaagcaa aaatgatact aaataaaaat
    32821 aagaccgaaa tataaacata gacccacaaa ggctttccaa tcataaattc ctttgataaa
    32881 gccgctaacc ctgaatgatt agggaaaata aatcccaaca agatgaacaa ataagctggt
    32941 acactaagaa aactcatcac atacatataa ggcatcccac ctgcaggatt caacatgatt
    33001 tcgagataaa aatagcgttt aaatcgattg tgtaagccaa ttttattaac aggaaccaaa
    33061 tagcgagctc gatacataag ggcaagtaaa taagaaaaga caagggttaa taaagcaagt
    33121 aacacaataa tccctgttgg aatgtgtact gtctgaaatg tttccaaaac atcctgagga
    33181 atatttaaaa ccatactgga taggagaatg actatagaac ctccaatccc catactcgca
    33241 tttaaatctg acaaccaaac aagaaaaaat gttcctgcta tcagcaatat tgtattcatt
    33301 agaacaacca atattgcaga ataggaggat tgtactggca gtctcaagct aactgccaat
    33361 gattgaatga cagctatcat caaggtcagg tacattttac ggcgatcttg tatttctata
    33421 gacgtagatg ttaaacccaa ccgtttagaa aaagaaaaca tctgccataa aatcatagct
    33481 gacatccaag gggacaatcc aacagaaaaa attgacaaac ttcttagatt tccacctgtt
    33541 agggcggctg agaaggctag ataggctgtt gaacctccta aaaaatcttt agtatttagg
    33601 tcaacaaaag ggagagtaat acgacttccc aatacataga taaacagtag aaataaggta
    33661 aatagtcctt tttttactgc tattgacgaa taaatcttag tcataaaaca ctcccctcac
    33721 cttcattgtt tgtgatatgg taaataacaa ttcttttatt tcaactttta ccatttcttt
    33781 gttctgcatc aaaaaacaac tttaatctga aacaaatatc tttatattcc tcagtatctg
    33841 ttaattgatg gtattctaaa gtttgcttat aatcttttaa aagattgaca aatcgaatac
    33901 gcagaacgga gacatccaaa ccagccaaga cacaatccga tattttctta gaaaacactt
    33961 caacaatatc tcttgcccag gaaagatcaa attccgttct catgatgctt cctgaacgtc
    34021 ttctatacag atagagatta tcgtttataa agacgatttt agaggctaaa agataaaagc
    34081 gatgcatagt tgcttcatca tcaaagcggc gaccatttga aaagtgaact tcattgaata
    34141 attctttttt aatcaactta aatgtcggca atataaaggc cgagctattg aatttccaat
    34201 ctcctgcttg acggttcata atttcttgta tagctaattc ttcgacgcaa aaatcttgcc
    34261 ctgttacata aaaataaaaa ttcccgtcac tttcgtcata attatagtaa ttccctataa
    34321 caacatctgc atccttttct tggacttgct gataaagagt ttcaatcata ttttctttta
    34381 cgatatcatc tgaatcaaca atcgtgatgt actctccctt agctacacta atccccatat
    34441 ttttagcttg tgctgccccc ccttattttc ttgatgcaat actcgcacac gattatcttg
    34501 catcataaaa gcatcacaaa tttccccaga attatccgta gaaccgtcat caactaaaat
    34561 aatttctata ttttgatagg tttgcttcag aatatgctcg acacactcca ctaaatattt
    34621 tcccgtattg tatatcggta ccacaacact aattaattca ctcattactc tatctctata
    34681 ttcttcattc tatccactaa atcatctggt ctctccacag aaaaaatacc gtcatagagt
    34741 ccatcatcca tacttttacg tgtgatatca aaagcgaaga ttttcttgcc actttcttgt
    34801 gcccttgtaa ctacattaaa aacctctcca cctgtattaa tatctaaata aactatagaa
    34861 tcgtccaata gccaatcaat tctactatgt aatacatttt gatatactgt tacattcgta
    34921 tactgtgata gagaggtcag ctcctcagaa caatcacacg gtgcagccaa atgaaaatgc
    34981 caatcaggta accgttgtac taaatactct aaatgtttta tatctgcact ccatgtcaca
    35041 agcatcactt gttttttaga ctgattgctt ctttcaaaat aatttaaatc ggaacgttga
    35101 aaagcaatct ctgaccaatc caaatctcta taaacccacc ataattcacg tagtctagat
    35161 atactatatg tattccaagg tttatcatga ctagcatagt gaacaattgt aggtggattg
    35221 tcatctagac gttcacattc ttgagcaagg tgataaatat caacacccac catataatta
    35281 tatgttttat ctaaggctag ccaattatcc tcaaaataaa tatttaaaat actctgatcc
    35341 ccaagatgaa caacttgatt ttgctcggcc gctaattcca ataaactatt gacaatagag
    35401 tgttctttcc attttgcaac atccattagt aacataccag cattaaatcc agattttcgt
    35461 ccttcatagg catagacatc atcaacagca ccaattgaat atcctttgag atctatctca
    35521 aacaaagtag ctagttcccc agttacaatg atatcggaat ccagatacaa taccctatca
    35581 gattcaacca cttctgtcgc aaaaaatcta aagtaagaag cataatttat atgaggtcct
    35641 gttttatagc tttcaaaaag ttctttatca atgtgtacac tgcgaattgt agaattcaca
    35701 acttccattt ttctccccaa taatttaaac cattcaggag ctatatcact gttgagaata
    35761 taaaaatcaa catctctatt gtgatacaat acagacttta tagtcgtctc taaaggaata
    35821 agataggcat tatctgccgc taatactatt gattttctca tactgttctc tacctcatgt
    35881 aagatctgat tgctgcaacc atttttttcg gaatggagct tggatagata ccttcatatg
    35941 aaatctcaga aagattttca gagcaagtat tgtcgaaagc tatcattggt tttttgtact
    36001 taagcacaaa ctcatatgca tcttctaatt ttcgatcatg attcaaatcc aaatacaaat
    36061 ctgaagctat tactatttgt tccaataaca ttggtaagga atttggatat acggtaacat
    36121 taggaaaacg cgttaaagct agtagttcat ttgccatatt tgtataagca acaatatgaa
    36181 aatgaacttc tggcaattgc tccgccaaat aatcgatttt ctcgacacac caagaattcg
    36241 ttaaattaac acattgtaac ttaaatattt gtgatttact aggatacttc acactctttg
    36301 aaaaccattc atttaaaata acagaccaat ccatcaaaga gtattcccac caaacttctc
    36361 ttagacgtcc aacagaaaat tgattccaag gcttatcctg agaaatatag tgtaaaatta
    36421 gtggcagtgg ttcgagcgga atatcaaaaa tgaattgatg tttaaaggct gccgccccat
    36481 aatcatatcc tatttgaaaa ttatattgat cttcaaggga actatattga tctttaaaca
    36541 acatattcaa aattgactgg tctccttctt ccacattctc atgttctttt tctgttaagt
    36601 caatcaattt ttgtcgaata gtttcagatc cccatttttt gttgttaatc aagagaacac
    36661 cagcattgaa gccgactcct gctccaaagc aagaacgagc tgctgccaaa taattttcac
    36721 ctaagtctaa ttcaaacaaa tcggtcaaat caccagtcac aatcaaatca ctatctagat
    36781 agagaacttt atcttctgtt acaaaatctg gaataaaata gcgtgcaaat gtcatatgat
    36841 tgatatgagg taatttatta gaccaattca tttgaaactg tgagccaatt aacttgcagt
    36901 caatcaagtc gccccccatc tcttgtaaat atattcttat ttgactaaac cattcctgag
    36961 gaatgtcctg atttagcaga taaattttca aatgactatt gtgtctacag agtgacttca
    37021 tcgccgtttc gatttgtcga atataagcgt aatcacctgc aaatgctaca gcgcgtttgg
    37081 tatttctcat tttaaatcct tatcatttat tttaaatagt ctagtttaat attcgtgcaa
    37141 caatctgact gttataggtt tcatcatcaa taaattcaat atcttgatca aaattatact
    37201 ctgcagtatg tttatgagaa aatttaacct tagttttagc tcccattttc atccattcat
    37261 actctgagtc aatatggcct acatccaaaa cttgatagcc catctggcat agattataac
    37321 tcagaacttt tgctgtagga cccagcatac ataaaatcaa gcgaccacca gcatactttt
    37381 caatttcttg ttcaatttca tgaactctag aaaaggcact atgagaagga cagataattc
    37441 gcttaataga atttgcctca tcgaataaat catttccgac acctgaacga gaagtcgcac
    37501 cttcgactat cagtaagtca cggttttccc aaatgctttt caatttttca aattgagctt
    37561 tagcttgact cttgtcttca aaatcgatat aagggcgaga tacaaaggtt gagccatacc
    37621 atgaatcact gcataactct ctgtaaaaat ccatataatg atccatgtga tctttccaaa
    37681 atggaatcgc ccacgatgta aacctaaaac gatctgtaaa agcatcagga aggcacacta
    37741 ctaaatcttc tcgactttct tggccgataa tgtccctcat gattgaaacc aactcttcat
    37801 cataatcctg gtagggaatt gaatgccctg caagcatatt gatttcccca tctccaaaac
    37861 gaactaaaga agagttgtgt tcaataatat aatccaaggt ttcatctatc cctttcacct
    37921 ggattatatc aagcggtttt tctagcatat ccttagttat caatttttgc aaatcagcca
    37981 acattcgttc aggatgttca cttgaataca acctttggcc attattccca ttttgagatt
    38041 tataaaaggc tagtataggt ttagatagat gagccatttc tgcaacgata tcggatgttg
    38101 aagtcagtag gttgatatct aaataagcat ccatcttctc cttcaactcg tctagcttat
    38161 ctctagaaat tgccggatag agctgaatat taggataacg attagacaaa tcatataatt
    38221 ttggccccat agctgtccaa gcagcaactt gaaaaacaac atttggcaac tgtccagcca
    38281 agtaatccaa ttgttcgata tcctgagaag ccgtaaacgt taaacaagtt aaacttggaa
    38341 gttgtcgaaa acaggtaaga tgtccgtttt tcttaaaatc tttaatcgta tcaatcataa
    38401 aggaaacttt cccattttcg aaaacgattt gtcctaactc tccgtgctga gtcgattgaa
    38461 aagctagtag cgttttttct tgttcttgca aagattttaa aaagttctca tctgcactac
    38521 catgattgat atccaaatat agatttgttg actttttcag cttatctaat acaggaggaa
    38581 caatttgtgg atgcaatctc acattatcat acacagctaa ttttatcagc ttatcaccca
    38641 tatccgtcca agcagcaata tgaaatacca catctggtaa agctgtgact aactcttcta
    38701 ttccttctaa atcttgggaa tttgtcaaag ttaaacaaga aaattcctta tctaaagacg
    38761 atgtcagttc aaactcccct atatgatgtt gtaaaatttt agtccattcc aaatcatgaa
    38821 attcccacca taaatcacga taacgattgg ctatcaaggt ggtccagggt tttctgtaag
    38881 acacaaaatg aataatacta ggaggtacta actcattaaa ataattttcc catttattat
    38941 aaaaagcagt tacatcatga cccacttgaa ggttaaattc tttatccagc tctaaccaat
    39001 catcttgtaa gacctgatta aaaatcgttt gatcaccatt aaaatgctcg aaacggcctt
    39061 cttcaacttc cttcattgta acaatgctct gttcaattag tcgttctttt aatttctctt
    39121 gacgccattt tttattgttg attaataaaa cacctgcatt aaatgtaatt ccatctgtat
    39181 ctttaactgc tgcgagtgat ttttcttcta aacaaatact aaataatttc tctaaagaag
    39241 tatttacaat caaatcactg tctaaatata aaaccttatc ttcttggata taatctgcaa
    39301 taaaatatct agtataggta atgctactaa tgtgatcttg cttttcccaa tcttgaaaca
    39361 cagtttgttc aggtagcttc acatcgataa tctcactacc taacatgcga gctatttttc
    39421 gtggtttgcg aaaccaatct ggcataatat cttgatttaa aatataaatc ttaacatctc
    39481 gattgtggta taaaatagat tttatggttg tttctaactg cctgatgtaa ttacgatcac
    39541 cagctaatac aattgtttta atcatcttgt tctcttattc aactcccaaa tggtaaattg
    39601 catctaccaa taatttttta gtaaaataac cttcttttag caaataacta aaggttttta
    39661 tccgattcgt catttcttga tattcttgta gattcatttt atcaactatc gcatgaactt
    39721 cttctagact attcgccaca aagcctaagc cttgatctac tataaattta gcagttgaca
    39781 agctacttgg tacaatgact gggatgcccg ctgtcagata ggtactcacc ttatgagata
    39841 tatttaaggt ataatattgg ttgctttctc catcgttttg ataagttccc cagacaaggc
    39901 caaatccacc ctttgataat tctagcaaca attcctcatc ttttttccat ccttcgatgc
    39961 tgagatttct agcactagaa ctagcttccc ctttatttga aaatactctc aaaggcgtat
    40021 cttgagacca attttgtaag tctggaaaac gctctaaact tccagcaaaa aaaagttctt
    40081 ttttaaaagc aggggtgtat aaggataaat catgaggatg atcccacatc ccttgaacaa
    40141 gaatcttctt agtcgtcaat ccttcttcca tcaggcgtgt tttcattctc tctgacggca
    40201 ctatcaaaac atctgataga ttatacatgt acatatagtc tttcatgaga taatagttac
    40261 tatcaaacat gaggggaaca acatcatgga taaagcaaat aattttcacc tgcatatcct
    40321 tcaacttatc aaacaagaga cgatcaaatt caaagccatt ccaggttgga gactgaaaga
    40381 ctaaaatatc cccaatagaa atactggcca taataccatc cagacgctta ttcatttcag
    40441 aaggactatc tgaagcaatg ttgtaaaaat aaataccaac ctctctaaat cccagttgac
    40501 tagctatctt ttgaacagca ttttgagcta agataaccgt actatcacca gccatgccgt
    40561 ataaatttgt taaatgtagt ttcatattac gctatctcat tttttattac tatctacgga
    40621 agtaaagaca atttttccat cattcttcta taaatctctg tgaactgcat attttgttct
    40681 tctaattttg ctatcactct ttgtaatcta tttttataaa tcaaaatatg attggtcaag
    40741 tcatagtctg aacttgctaa aatagctatc ttttcttccc tagccccgat ttcatcatac
    40801 atacgctttt cactccatgt attcgataaa gtatcagata aaccaacacg gtaccagtaa
    40861 acacaacgat tcaaatagac tatcctcgaa gctcttagaa gtaccttcca tgtccagtaa
    40921 gtatcctctg caatttttcc tataggaaat ggtaaatctt gtagtaactc tctcttgaat
    40981 aacttcaaga cagctacagt ccagttccca tttctgactt cttcgacacc ttccctatcc
    41041 atgattgctt taccttctat cacttccaga gaatcatctg gatccgtaac ataagtcata
    41101 tacacatagc gtgtttcatc ataagaatta taacgcccga tactaatatc tgcgttttcc
    41161 tttttcaaag caccatataa tcggtctaaa gcatcatgtt ccaaccaatc atcagagtct
    41221 acaaaagtaa tgtacgcccc ccccgaacat tcaataccta ggttacgagc tgatgaaaga
    41281 ccgccgtttg ctttctcaaa atatttgaaa cgagaatctt tctctacaaa ttcttcacat
    41341 attttggatg aatgatctgg agagccatca ttaaccatga tacattcaaa attcggataa
    41401 gtttgttttt gaatactatc caaacactgt cgcaaataat tctcaacgtt gtagattggg
    41461 actacaatac taattagttc attttccata tactaacttt cctagacttg atttattcta
    41521 tttccctctt aatctcttct ctttacaaca agatttccat tattataaac tacactgttt
    41581 gatggaatat cattgcgtat gagacaacct gctccaataa tggtattatc cccaatcgtc
    41641 actcctttta aaatcgtgac attacttcct atccagcagt ctctgccaac tctaatcggc
    41701 gctgtagtcc actgccactt ttcaatcttt tcagcagtat aaatatggtc gtgatcataa
    41761 aaacgaacac cctctcccat catggtacca gctccgattt caattctttc catacagtta
    41821 aaactacaag agttgttgat aaaaacacca tcatgcagta ttaacttacc agaagagaca
    41881 tgaaaatttt caaaatttct gcagatgaca tttgctccta caatgaagtg agccttatca
    41941 tcgattttaa agacattcca agtcccatct tggatgattt tttcttgatg attggtgcct
    42001 actctgactt cattcagata gtctctcact ctagaaacca atttgtctgg tgtacttgat
    42061 agaaaaactt cctgcccctg atttccatgg actgtattgt caaaagcaaa gacagatttt
    42121 ccagcctgta caaacttgga gacaatagca tctacttctt gaaagtgatt gatatctagt
    42181 aaaaagtcac aggtatcgac tagaaagttt agctgttctt catttgtaat cgttcggaga
    42241 cggacattat agttcgtttc taagctacgg attttctcgg aaaattgaac aggtgctgca
    42301 atataaaaac agatatttgg caaggattca aggagataat ccaactcttc aatctgatca
    42361 ctaacagtca aaatcagagc atctcctact aaatgatttt tcttcatttg cttatttctc
    42421 tcaatttctc aatcattgct tgaacttggt caacagcata tacctcctga cctgcttcat
    42481 aggttttggt attttcaaag gacaaaatag tttttccaag tcttgcaaat tgattgataa
    42541 tttcctctgt tttttcacca tgattaatat ctaaaagtac ttgactggtt tctaccaatt
    42601 cattatcgac atctaccaaa tagtgaattc cgttaaatat agtcacgttt ggataaattg
    42661 tcatctgagc caatcgatca ctaactatta ctctagctgc tatcttaaac tgaatatcag
    42721 gcaaggattg aaccaatgtc tcaatttgtt caatatggtc tgaggcagta tagattagac
    42781 aagtgaaagg ttcctttatt ggatagatgt gagatctttg taatggatgt aaatgatggt
    42841 tttgtcccaa ttctgtccat tcaagcccat gatagtacca ccaaacttca cgataggttt
    42901 gggccgccaa atctttccac ggtttccgat gagaaagata gtgaataata gcaggataat
    42961 cctgaccctc aggcaattga taatcagcaa actgtttatg aatgacaata tgattataat
    43021 caaagtccaa ttccaaccat ttatgttcaa aaagcatatt caagatgctc tgatctgcct
    43081 gatccacctt atcatgccat tcattggtta catcaattaa tttttgggtc atattctctt
    43141 ttttccaaaa agcattgttt accaagagaa caccggcatt aaagatttct tgaccaaaat
    43201 aagctctgcc cccaaaatct ctaacagcag ccaaaggata atcttgtaag tctgtagcaa
    43261 acaaatcatc aagatttttc gttacaagta aatcacagtc caagtagagg gccttatctt
    43321 cttgcacgaa atcagctatg aaatagcgta aaaaaactgt gtaactaata tccgttttat
    43381 aacatgaaat ttgctcagaa gttacccgac aattaataat ttctgagtca aacttctcta
    43441 agcgcttatt taattgctta atccattcat ttggaaaatc gctatgaatc agataaaaac
    43501 gaatcgaacg attatgataa caaatagact tgattgtcgt taaaacttgg tctacatagc
    43561 catagtttgc tgctaggaca atggctttct tttcacttga ttcttgtacc gttaactgat
    43621 ttaaaagtct ttttttcatt tcaaactctt tatatattgc tgtgtcagat aaaccactag
    43681 cttgaccgtt ggcgagactg acttccaaca tctgacgata aactgccaag tgtttctcta
    43741 gaggatatcc catattagct agtagcgtaa tacgttcaga catagcatca actaaggcgt
    43801 gcatccactt ttctgtccaa actcttgata gactaccttt tctaatccga taagcataaa
    43861 gacctttatt taaataaatt accttttccg ataataaata taccttttga ttgaggtaac
    43921 catcttctcc taatttaccc atgtcaaagc gcaactgctc aaacaatctt gccttataga
    43981 gtttaccaca agcagatatc aaagcaaaac tcttcatttc ttgagtttca taacaagttc
    44041 tcaaagatgg aaacattgtc atatacctta tcataatagg agtctcctga tatatgaaag
    44101 tagaacattc cttcactttc gttgaaagaa tagtaattcc caactgcaat atcagcttga
    44161 tattctgtta tttttttata tagggtttct acataatcta actcaatcca atcatctgaa
    44221 tccacaaagg tcacataatt tccggacata ttattcagac cggtgtttcg tgcggcagaa
    44281 ataccagcat tttcttgttc tatatagaga attcggtgat ccatttctga aaattcttta
    44341 caaatttcac ctgaagcatc cgtagaacca tcattaacga caacaatctc aatattttta
    44401 tatgtttgag aaataatact atctagacat ttcctcagat agttttctac attgtatact
    44461 ggtacaatga ccgtaatttt atcatccact agcaattttc tccttgattt atgtgcgcga
    44521 gttagtttag cctaacttta caggttgtct tactcttctt catcacgttt acggcgtttc
    44581 gcaaccaatc caatacctgt aacagctgct agaactccaa gtaacacaga tccaattgac
    44641 gactcagtac ctgtattagg caattctttt tgggatttac ctgtcgatcc agaagcattt
    44701 ccaacttgtg agttcgaatg gtttgctgaa tttgaaactg atgtacttgc tgaggctgac
    44761 gcactcgttg atgctgactc agacgcactg gttgatgccg attcagacgc tgaggtgctt
    44821 gctgatgctg aggcactggt tgacgctgaa gctgaggcgc tagtacttgc tgaagccgag
    44881 gcactggttg atgctgaggc tgaggcgcta gtacttgctg aagctgaggc acttgtcgat
    44941 gctgaggccg aagcactggt acttgctgaa gccgaagcac tcgttgatgc tgaggctgaa
    45001 gcactggttg acgctgaagc tgaggcactc gttgaggctg aagccgaagc actcgttgat
    45061 gcggaagctg acgcactggt acttgctgaa gctgaggcgc ttgtgcttgc tgaggccgag
    45121 gcacttgttg aggccgattc agaagctgag gtactcgttg atgcggattc agatgctgag
    45181 gtgcttgctg aggccgaggc gctggttgat gcagaagctg aggcactggt tgacgctgaa
    45241 gctgaggcac tggttgaggc cgattcagaa gctgaggtac tggtgcttgc tgaagctgag
    45301 gcactcgttg atgccgattc agacgctgag gtgcttgctg aagctgatgc acttgttgat
    45361 gctgaggctg aggcgctggt tgatgccgat tcagacgctg agat
//
LOCUS       DAVBED010000010        45159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBED010000010 DAVBED010000000
VERSION     DAVBED010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.010"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ547_000567"
     CDS             complement(56..1066)
                     /locus_tag="VQ547_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2542468.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ547_000568"
     CDS             1215..2384
                     /locus_tag="VQ547_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2542469.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTHEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ547_000569"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ547_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2542470.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ547_000570"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ547_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2542471.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ547_000571"
     CDS             4146..4379
                     /locus_tag="VQ547_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2542472.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQ547_000572"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQ547_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VQ547_000573"
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VQ547_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2542473.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5864..8017
                     /locus_tag="VQ547_000574"
     CDS             5864..8017
                     /locus_tag="VQ547_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2542474.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VQ547_000575"
     CDS             8030..9379
                     /locus_tag="VQ547_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2542475.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VQ547_000576"
     CDS             9550..10257
                     /locus_tag="VQ547_000576"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2542476.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10459..14184
                     /locus_tag="VQ547_000577"
     CDS             10459..14184
                     /locus_tag="VQ547_000577"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2542477.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VQ547_000578"
     CDS             14277..15719
                     /locus_tag="VQ547_000578"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2542478.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VQ547_000579"
     CDS             15756..16778
                     /locus_tag="VQ547_000579"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2542479.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VQ547_000580"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VQ547_000580"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2542480.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VQ547_000581"
     CDS             17404..17913
                     /locus_tag="VQ547_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2542481.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VQ547_000582"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VQ547_000582"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2542482.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VQ547_000583"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VQ547_000583"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2542483.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21272..21760
                     /gene="purE"
                     /locus_tag="VQ547_000584"
     CDS             21272..21760
                     /gene="purE"
                     /locus_tag="VQ547_000584"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2542484.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21747..22838
                     /gene="purK"
                     /locus_tag="VQ547_000585"
     CDS             21747..22838
                     /gene="purK"
                     /locus_tag="VQ547_000585"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2542485.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22848..23075
                     /locus_tag="VQ547_000586"
     CDS             22848..23075
                     /locus_tag="VQ547_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2542486.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23138..24436
                     /gene="purB"
                     /locus_tag="VQ547_000587"
     CDS             23138..24436
                     /gene="purB"
                     /locus_tag="VQ547_000587"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2542487.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ547_000588"
     CDS             complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ547_000588"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2542488.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28744..29460)
                     /locus_tag="VQ547_000589"
     CDS             complement(28744..29460)
                     /locus_tag="VQ547_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2542489.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29808..31595
                     /locus_tag="VQ547_000590"
     CDS             29808..31595
                     /locus_tag="VQ547_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2542490.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31592..32068
                     /locus_tag="VQ547_000591"
     CDS             31592..32068
                     /locus_tag="VQ547_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2542491.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32096..33001
                     /locus_tag="VQ547_000592"
     CDS             32096..33001
                     /locus_tag="VQ547_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2542492.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32988..33803
                     /locus_tag="VQ547_000593"
     CDS             32988..33803
                     /locus_tag="VQ547_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2542493.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33810..34214
                     /locus_tag="VQ547_000594"
     CDS             33810..34214
                     /locus_tag="VQ547_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2542494.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34513..35679
                     /locus_tag="VQ547_000595"
     CDS             34513..35679
                     /locus_tag="VQ547_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2542495.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35795..36832
                     /locus_tag="VQ547_000596"
     CDS             35795..36832
                     /locus_tag="VQ547_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2542496.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37040..37894
                     /locus_tag="VQ547_000597"
     CDS             37040..37894
                     /locus_tag="VQ547_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2542497.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38044..38301
                     /locus_tag="VQ547_000598"
     CDS             38044..38301
                     /locus_tag="VQ547_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2542498.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38677..38769)
                     /locus_tag="VQ547_000599"
                     /pseudo
     CDS             complement(38677..38769)
                     /locus_tag="VQ547_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(38805..39101)
                     /locus_tag="VQ547_000600"
     CDS             complement(38805..39101)
                     /locus_tag="VQ547_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2542499.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(39091..39252)
                     /locus_tag="VQ547_000601"
     CDS             complement(39091..39252)
                     /locus_tag="VQ547_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2542500.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            39322..40086
                     /locus_tag="VQ547_000602"
     CDS             39322..40086
                     /locus_tag="VQ547_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2542501.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40699..42078
                     /locus_tag="VQ547_000603"
     CDS             40699..42078
                     /locus_tag="VQ547_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2542502.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            42092..42757
                     /locus_tag="VQ547_000604"
     CDS             42092..42757
                     /locus_tag="VQ547_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2542503.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42871..42966
                     /locus_tag="VQ547_000605"
                     /pseudo
     CDS             42871..42966
                     /locus_tag="VQ547_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            43112..43561
                     /locus_tag="VQ547_000606"
     CDS             43112..43561
                     /locus_tag="VQ547_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2542504.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            43718..44128
                     /locus_tag="VQ547_000607"
     CDS             43718..44128
                     /locus_tag="VQ547_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2542505.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44244..>45159
                     /gene="pavB"
                     /locus_tag="VQ547_000608"
     CDS             44244..>45159
                     /gene="pavB"
                     /locus_tag="VQ547_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2542506.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        12583 a         8713 c        10653 g        13210 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact catgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actaggaata gatcatacca gaggtagctt agaaatagca gggacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgacagtaa aaaatcaatt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     6661 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     6721 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     7681 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     8161 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatctcttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttaaaaa aacatctgct atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
    10321 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaacggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtgacca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgcct tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgattttc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcggaca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgatga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaaacaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacta aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ctggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgtttctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc tttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    20521 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcacgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctaaatt attcaaaggg
    20641 tgttgagttg ccagtcaaaa ccgatggcga catcattacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga acaatcaccg
    21121 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    21181 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    21241 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    21301 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    21361 agcctacgaa aagaaagttg tttccgcaca ccgcacacca gacctcatgt tcaaacatgc
    21421 agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg gcgcagcgca
    21481 tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc
    21541 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    21601 tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct ttgccctccg
    21661 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    21721 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    21781 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    21841 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    21901 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttatgagt
    21961 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    22021 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    22081 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    22141 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    22201 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    22261 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    22321 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    22381 ctaagaccat cgtaccagcc cgcatttctg aaagtctagc agacaaggct aaagctatgg
    22441 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    22501 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    22561 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctgggtgtt ctcggagcac
    22621 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    22681 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    22741 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    22801 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    22861 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    22921 gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa taccccgaaa
    22981 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    23041 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    23101 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    23161 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    23221 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    23281 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    23341 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    23401 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    23461 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    23521 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    23581 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    23641 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    23701 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    23761 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    23821 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    23881 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    23941 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    24001 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc actcatcagc
    24061 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    24121 aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    24181 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    24241 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    24301 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc aagaagaaat
    24361 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    24421 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    24481 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggccatga
    24541 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctcta
    24601 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    24661 gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    24721 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    24781 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    24841 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    24901 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    24961 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    25021 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    25081 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgc tcacctttga
    25141 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    25201 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    25261 ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg ccttgaagag
    25321 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    25381 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    25441 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    25501 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    25561 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    25621 gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca atagctttct
    25681 tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag tcaccgttgg
    25741 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    25801 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    25861 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    25921 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    25981 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    26041 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagttcatcg
    26101 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    26161 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    26221 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gttacttctg
    26281 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    26341 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcatcga
    26401 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    26461 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    26521 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    26581 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    26641 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    26701 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    26761 taagtgtttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    26821 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    26881 aagcagctac catactaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    26941 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    27001 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    27061 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    27121 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    27181 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    27241 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    27301 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    27361 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    27421 taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc ttcccaaaat
    27481 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    27541 gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    27601 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    27661 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    27721 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    27781 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    27841 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    27901 cacgttcctt tcctgcctct gtttccggtt tgtcatcctc tgctttcgct tcatcttttt
    27961 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    28021 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    28081 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    28141 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    28201 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    28261 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    28321 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    28381 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    28441 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    28501 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    28561 tttaaactta agatttcaga ttggtcggaa aaaatacgta tatatatcta gtataatttt
    28621 tggttctatt tctataaaat attccacaaa ttatagaatt ttccaaaaat aggtaagcgc
    28681 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
    28741 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
    28801 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
    28861 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
    28921 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
    28981 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
    29041 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
    29101 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
    29161 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
    29221 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg
    29281 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
    29341 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
    29401 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
    29461 atttttacct ctattttcct tctccatagg aaattttacc ataaaagcga aaaaaatagt
    29521 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
    29581 catattttat caatgtattc tatacaaaat tattttaggt cccatattcc gaatttaaag
    29641 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
    29701 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
    29761 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
    29821 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
    29881 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
    29941 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
    30001 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
    30061 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
    30121 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagta tatatcgagg
    30181 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
    30241 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
    30301 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
    30361 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
    30421 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
    30481 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
    30541 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
    30601 aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt
    30661 tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt
    30721 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
    30781 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
    30841 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
    30901 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
    30961 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
    31021 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
    31081 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
    31141 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
    31201 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
    31261 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
    31321 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
    31381 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
    31441 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
    31501 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
    31561 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
    31621 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
    31681 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
    31741 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
    31801 tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
    31861 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
    31921 accagaaaca cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
    31981 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
    32041 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
    32101 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
    32161 gacgatcgtt tcatctgcag gttctcctgt atttgctggt ttcattactg gtttaatcat
    32221 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
    32281 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
    32341 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
    32401 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
    32461 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
    32521 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
    32581 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
    32641 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
    32701 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
    32761 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
    32821 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
    32881 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
    32941 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
    33001 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
    33061 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
    33121 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
    33181 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
    33241 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
    33301 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
    33361 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
    33421 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
    33481 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
    33541 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
    33601 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
    33661 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
    33721 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
    33781 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
    33841 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
    33901 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
    33961 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
    34021 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
    34081 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
    34141 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
    34201 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
    34261 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    34321 gacttcgtca gtcttatccg gcaacctcaa agcagtgctt tgagcagcct gcggctagtt
    34381 tcctacagat tttagttgga actcgattca attcatgtga caacgtgaaa atcgttagag
    34441 cattttatat agaatataca tgggaatgga gcttactccc attcccatat ttaatagaaa
    34501 aagaggaact caatgctaca ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc
    34561 actacgcgtg aaatctacca acagcctgat gtatggagag aagcttttga attttatcaa
    34621 gcaaaacgtg aagaaattgc agcctttcta caagaaatcg ctgataaaca tgactatatt
    34681 aaggttatct tgacaggtgc tgggacttct gcttatgtgg gagatacctt gctaccttac
    34741 tttaaggaag tctatgacga acgcaaatgg aatttcaatg ctattgcgac aacagatatc
    34801 gttgccaaac cagcaaccta tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct
    34861 cgtagtggga actcgcctga aagtgtggcg actgttgatt tggccaaatc cttggtggat
    34921 gagctttatc aagtgacgat tacttgtgca gcagatggta aattggctct tcaagctcac
    34981 ggtgatgacc gtaatctctt gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc
    35041 atgacttcta gctttacgtc tatgatgttg acaactctct tggtctttga tcctacagaa
    35101 tttgctgtta agtctgaacg ttttgaagtt gtatctagtc ttgcccgtaa agttttagac
    35161 aaggcagaag atgtcaaaga gctcgttgat ttagacttta accgtgtcat ctatctaggc
    35221 gctggtcctt tctttggact tgctcatgaa gctcagctca agattttgga attaactgct
    35281 ggtcaagttg cgaccatgta tgaaagccca gttggcttcc gtcacggtcc aaaatctctt
    35341 atcaacgaca atacagttgt tttggtcttt ggtacaacga cggactacac tcgtaagtac
    35401 gacttggact tggttcgtga agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg
    35461 agtgatcaag cttttggtct tgaaaatgtc aaagaagtgg tccttggttg tggcggtgtc
    35521 ttgaatgata tttaccgtgt cttcccttac atcgtttatg cccaactctt tgccctattg
    35581 acttcactca aggtagaaaa taaaccagat acaccgtctc ctacaggtac agtaaaccgt
    35641 gtagtacaag gtgtcataat tcacgaatat caaaagtaag acagtgttta tgaattcttg
    35701 acaagaggat ttgtaaatta tcagataaac catagattgt cagtacgctt tctatggttt
    35761 gtttgcttga gagaaatagt aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt
    35821 tggaaatgtt gagggtgagg atgtcttggc ctatcgattt gagacagacg gtggctacca
    35881 acttgaggtt atgacttatg gtgcgactat cttgcgctat gtcgcacctg acaaggctgg
    35941 aaattttgcc aatgttatct tgggatttga tgactttgat agttatgtag gcaatagtcc
    36001 caagcatgga gcaagtgtag gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct
    36061 caatggtaag acctatgacc ttgaggttaa taatgctagc aactgtaatc acagtggttc
    36121 aactggttgg gattccagct tgtttgaagt tgaagaagta agcgatcatg gcttgactct
    36181 ctacacagag cgtacagatg ggacaggagg gttccctgga aatctcaaga tttggatcag
    36241 ttatcacttg gaagaaactg gtgcctatga aatcagctac aaggtaacga ccgatcagga
    36301 tacgctggtc aatccaacca accacagcta tttcaacttg tctggtgatt tcacgcagac
    36361 gattgaccgt catgtcttcc aactaaacac agagggcatt tactcaatcg ctcctgacgg
    36421 tgttcctgcc aaaactccag aagccaaccg tgatgtggtc aaacacatct acaatggtgc
    36481 cttgttgaag gatatctttg cagaagaaga tgagcaaatc cagctggcat caggtttgga
    36541 tcatccattt gcccttcctg caggccatga caatgctgga ttcctttatg accaaaattc
    36601 aggtcgcttc ctgcttttca agacagaagc tccttgcttt gtggtctaca cagcaaactt
    36661 tgtggatgaa agtgtcatca taggaggtca gccaatgcta cagcacaatg ggattgctct
    36721 tgaagcgcaa gctttaccag atgccattca cagtgacctt aaaggccaag tcattcttaa
    36781 agctggtcaa accttcacca gtaagacacg ttatgaactt gttgtgaaat aaaaaaagct
    36841 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
    36901 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
    36961 ttatctggct tgactttctt gatggaaatt atataatagt tgtaacaatg ataattacaa
    37021 ctagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
    37081 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
    37141 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
    37201 acagctgatt caagcacaag agagcggaga agtgagggaa tattatggtc tttaccattt
    37261 ggccattctc ttgcccacac gcaaggcttt agctgatgtc ttgaaacacc tgacagattt
    37321 acaaattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
    37381 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
    37441 agaagatgga cgcattatcg gagtgacaga ggctcttgcg gcgcaggaca tttatgagtt
    37501 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
    37561 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
    37621 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
    37681 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
    37741 ctactatgtc atcgaagtcg cacacaaaaa agaactatta acgattgccc aacgagcaca
    37801 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
    37861 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa
    37921 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggc
    37981 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
    38041 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
    38101 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
    38161 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
    38221 atcaatcagc cactagatga ttctgaagct caaaaggaac gcttagaaaa ggctatccga
    38281 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
    38341 tattagaata gtttaatggg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
    38401 cgcatagtat caggtattga aatgtactga ccccaaaaag ttagattttt tctgtctaac
    38461 ttttggggtg cagttcataa gaaccttggt aatatgcgtt ttattatggg gagatttata
    38521 cttttcgaaa atctcttcaa accaggtcag cttcaccttg ccgtagatat ggttactgac
    38581 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttccatc
    38641 cacaacctta aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
    38701 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta
    38761 cttcatcttc tcatgaaatt gagtttttgc ccagttcctc ttgattattc tacttgacca
    38821 ggccaagcat tcataccacc ttctacgttg gtaacggtga ggccttggga gatgagaaat
    38881 tggcaggtag atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt
    38941 ttgagttctt tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca
    39001 tgtcctgctt ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttgg
    39061 tattttccat aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt
    39121 aaccattttg tatagtgaat aagcgccgtc aaggttttgg gcggtaaatc ctgcttgctt
    39181 gaggataggc tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg
    39241 ttttttgtcc agttcatcag cttcctcctt gacactttgt cagtttttga tacaatagta
    39301 caaaattaga ggaggtgggc tatgattcag aaacatgcga ttcctatttt agagtttgat
    39361 gacaatcctc aggcggttat catgcccaat cacgaggggc tggacttgca gttgccaaag
    39421 aagtgtgttt atgcattttt agatgaggag attgaccgct atgcaaggga agtaggggcg
    39481 gattgtgtcg gcgaattcgt ttctgctacc aagacctatc cagtctatgt catcaactac
    39541 aagggtgagg aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt
    39601 atggattggt tgattggcta tggtgtggag cagattatct ctactgggac ctgtggtgtt
    39661 ctagctgata tagaggaaaa tgcctttcta gtccctgttc gcgctctgcg agatgaagga
    39721 gccagttacc actatgtggc accttctcgt tatatggaaa tgcagccaga ggctattgct
    39781 gctattgagg aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg
    39841 acagacggtt tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt
    39901 gctgttgtgg agatggagtg ttctgctctt gcggcagtag ctcaattgcg tggggttctc
    39961 tggggtgaat tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt
    40021 gactggggct cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac
    40081 ctttagttgt actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
    40141 aaatatgttt aaacgaggtc accttcctct tgtcctaagc atgttgaggt tgggaaaaat
    40201 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ccttgatact atgcgtttta
    40261 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctttt caaaccaggt
    40321 cagcttcacc ttgccgtagg tatatgttac tgacttcgtc agtcttatcc ggcaacctca
    40381 aaacggtgtt ttgagctgac ttcgtcagtt ctatttgcaa cctcaaaaca gtgttttgag
    40441 caatctgtga ctagctttct aatcgatgcc ttggttctca ttgcctataa tcaaaaagag
    40501 aaattttctc ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt
    40561 tgacctatag tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc
    40621 attttttagg cttggtgtta gtagattttg ccttatccta tctaagtcat ttcgaacttt
    40681 ttatggtaca atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta
    40741 tctcgtttat cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc
    40801 tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat
    40861 catcttttca ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct
    40921 cacacctata atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta
    40981 gggctcatga cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt
    41041 agccgtgcaa ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt
    41101 gtctattcta tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt
    41161 tttcgcctta ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg
    41221 atctcagcct tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt
    41281 cagaccgatt tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt
    41341 tttatggtct ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac
    41401 tttcatacga agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact
    41461 actctctttc ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag
    41521 gttttagtta gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat
    41581 tatactcagg ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg
    41641 gcacctggag gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt
    41701 gcacgaagtg agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg
    41761 cgaacggttc aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga
    41821 ttgattctgc tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa
    41881 accatttcag ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa
    41941 ttggctctca gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg
    42001 tttgttagct tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca
    42061 gatattagta ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg
    42121 cttgggaatt tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat
    42181 cgctattgat gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt
    42241 gattggtgac atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac
    42301 cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa
    42361 gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct
    42421 agaaaagatt ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc
    42481 acagaccatt cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat
    42541 cgtggagatg aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg
    42601 tggcaaatac aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt
    42661 tgaatttgga ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa
    42721 ccagtatttg gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg
    42781 atgcccaaga tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag
    42841 gctggacttt atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc
    42901 aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat
    42961 agaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc
    43021 agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtata
    43081 agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg ccatttctag
    43141 ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg gtggtgagca
    43201 agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa tcgctgagtg
    43261 tttagctagc aagtatccta atatcgttag agccatctat caggaaaata aatgccatgg
    43321 cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag tagttgacag
    43381 tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc aggaacttga
    43441 gagcaagggt caagaggtgg atgcctttgt gaccaatttt gtctatgaaa aggaaggtca
    43501 gtctcgtaag aagagtatga gttacgagtc agtcttgcct gttcggcaga tttttgacta
    43561 ggaccaggtc ggaaatttct ccaaaggcca gtatatcatg atacactcgc tgatttatcg
    43621 gacagatttg ttgcgtgcta gccagttcta actgcctgaa catacttttt atgtcgatga
    43681 tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc ctgtcgattt
    43741 ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga tgattaagcg
    43801 cattgaccag caactcaagg tcaatcgact cttggtagac cagcttgatt tgtcccaagt
    43861 gagtcatcct aaaatgcgag aatatctgct gaatcatatt gaaatcacga cggtgatttc
    43921 cagtaccctg ctcaaccgat ctgaaacagc ggagcatctg gcaaaaaaac gccaattgtg
    43981 gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga ccatgttgag
    44041 ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat
    44101 caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga tttaagaaaa
    44161 attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt catcaaataa
    44221 agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat actcgttggt
    44281 ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc ttctttgtcc
    44341 tagttggtca gccaagttct gtacgtgccg atgtggtcaa tccgacccca ggtcaagtct
    44401 tacctgaaga gacatcggga acgaaagagg gtgacttatc agaaaaacca ggagacaccg
    44461 ttctcactca agcgaaacct gagggcgtta ctggaaatac gaattcactt ccgacaccta
    44521 cagaaagaac tgaagtgagc gaggaaacaa actcttctag tctggataca ctttttgaaa
    44581 aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa actgtagata
    44641 cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa caagtaaaag
    44701 gtggagtgaa agaaaataca aaagacagca tcgatgttcc tgctgcttat cttgaaaaag
    44761 ctgaagggaa aggtcctttc actgccggtg taaaccaagt aattccttat gaactattcg
    44821 ctggtgatgg tatgttaact cgtctattac taaaagcttc ggataatgct ccttggtctg
    44881 acaatggtac tgctaaaaat cctgctttac ctcctcttga aggattaaca aaagggaaat
    44941 acttctatga agtagactta aatggcaata ctgttggtaa acaaggtcaa gctttaattg
    45001 atcaacttcg cgctaatggt actcaaactt ataaagctac tgttaaagtt tacggaaata
    45061 aagacggtaa agctgacttg actaatctag ttgctactaa aaatgtagac atcaacatca
    45121 atggattagt tgctaaagaa actgtcgaaa aagctgtta
//
LOCUS       DAVBED010000011        42630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBED010000011 DAVBED010000000
VERSION     DAVBED010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.011"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            1..396
                     /locus_tag="VQ547_000609"
                     /pseudo
     CDS             1..396
                     /locus_tag="VQ547_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(441..1082)
                     /gene="plsY"
                     /locus_tag="VQ547_000610"
     CDS             complement(441..1082)
                     /gene="plsY"
                     /locus_tag="VQ547_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2542507.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1218..3161
                     /gene="parE"
                     /locus_tag="VQ547_000611"
     CDS             1218..3161
                     /gene="parE"
                     /locus_tag="VQ547_000611"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2542508.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3581..6052
                     /gene="parC"
                     /locus_tag="VQ547_000612"
     CDS             3581..6052
                     /gene="parC"
                     /locus_tag="VQ547_000612"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2542509.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6184..7206
                     /locus_tag="VQ547_000613"
     CDS             6184..7206
                     /locus_tag="VQ547_000613"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2542510.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7262..7966
                     /locus_tag="VQ547_000614"
     CDS             7262..7966
                     /locus_tag="VQ547_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542511.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8031..8720
                     /locus_tag="VQ547_000615"
     CDS             8031..8720
                     /locus_tag="VQ547_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2542512.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8717..9640
                     /locus_tag="VQ547_000616"
     CDS             8717..9640
                     /locus_tag="VQ547_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2542513.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9655..10299
                     /gene="pcp"
                     /locus_tag="VQ547_000617"
     CDS             9655..10299
                     /gene="pcp"
                     /locus_tag="VQ547_000617"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2542514.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10467..10697
                     /locus_tag="VQ547_000618"
     CDS             10467..10697
                     /locus_tag="VQ547_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2542515.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10747..10827
                     /locus_tag="VQ547_000619"
     tRNA            10747..10827
                     /locus_tag="VQ547_000619"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10781..10783,aa:Tyr,seq:gta)
     gene            10837..10908
                     /locus_tag="VQ547_000620"
     tRNA            10837..10908
                     /locus_tag="VQ547_000620"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10869..10871,aa:Gln,seq:ttg)
     gene            11070..12272
                     /gene="rpsA"
                     /locus_tag="VQ547_000621"
     CDS             11070..12272
                     /gene="rpsA"
                     /locus_tag="VQ547_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2542516.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12358..12855
                     /locus_tag="VQ547_000622"
     CDS             12358..12855
                     /locus_tag="VQ547_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2542517.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12855..14510
                     /gene="dnaX"
                     /locus_tag="VQ547_000623"
     CDS             12855..14510
                     /gene="dnaX"
                     /locus_tag="VQ547_000623"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2542518.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14538..14732
                     /locus_tag="VQ547_000624"
     CDS             14538..14732
                     /locus_tag="VQ547_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2542519.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14882..15652
                     /gene="sufC"
                     /locus_tag="VQ547_000625"
     CDS             14882..15652
                     /gene="sufC"
                     /locus_tag="VQ547_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2542520.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15680..16942
                     /gene="sufD"
                     /locus_tag="VQ547_000626"
     CDS             15680..16942
                     /gene="sufD"
                     /locus_tag="VQ547_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2542521.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16953..18179
                     /locus_tag="VQ547_000627"
     CDS             16953..18179
                     /locus_tag="VQ547_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2542522.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18166..18606
                     /locus_tag="VQ547_000628"
     CDS             18166..18606
                     /locus_tag="VQ547_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2542523.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18656..20068
                     /gene="sufB"
                     /locus_tag="VQ547_000629"
     CDS             18656..20068
                     /gene="sufB"
                     /locus_tag="VQ547_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2542524.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20299..21540)
                     /locus_tag="VQ547_000630"
     CDS             complement(20299..21540)
                     /locus_tag="VQ547_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2542525.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21643..22752
                     /locus_tag="VQ547_000631"
     CDS             21643..22752
                     /locus_tag="VQ547_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2542526.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23286..23633
                     /gene="ssrA"
                     /locus_tag="VQ547_000632"
     tmRNA           23286..23633
                     /gene="ssrA"
                     /locus_tag="VQ547_000632"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23816..23903)
                     /locus_tag="VQ547_000633"
     tRNA            complement(23816..23903)
                     /locus_tag="VQ547_000633"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23867..23869),aa:Ser,seq:gga)
     gene            24065..24805
                     /locus_tag="VQ547_000634"
     CDS             24065..24805
                     /locus_tag="VQ547_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2542527.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24802..25713
                     /gene="pfkB"
                     /locus_tag="VQ547_000635"
     CDS             24802..25713
                     /gene="pfkB"
                     /locus_tag="VQ547_000635"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2542528.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25710..27662
                     /locus_tag="VQ547_000636"
     CDS             25710..27662
                     /locus_tag="VQ547_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2542529.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27826..30051
                     /locus_tag="VQ547_000637"
     CDS             27826..30051
                     /locus_tag="VQ547_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2542530.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30096..30524)
                     /locus_tag="VQ547_000638"
     CDS             complement(30096..30524)
                     /locus_tag="VQ547_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542531.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30662..31804
                     /locus_tag="VQ547_000639"
     CDS             30662..31804
                     /locus_tag="VQ547_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2542532.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31813..33027
                     /gene="thiI"
                     /locus_tag="VQ547_000640"
     CDS             31813..33027
                     /gene="thiI"
                     /locus_tag="VQ547_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2542533.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33162..33986
                     /locus_tag="VQ547_000641"
     CDS             33162..33986
                     /locus_tag="VQ547_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2542534.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            34008..34747
                     /locus_tag="VQ547_000642"
                     /pseudo
     CDS             34008..34747
                     /locus_tag="VQ547_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34760..35926
                     /locus_tag="VQ547_000643"
     CDS             34760..35926
                     /locus_tag="VQ547_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2542535.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36434..37927
                     /locus_tag="VQ547_000644"
     CDS             36434..37927
                     /locus_tag="VQ547_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2542536.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37940..38986
                     /locus_tag="VQ547_000645"
     CDS             37940..38986
                     /locus_tag="VQ547_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2542537.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            39016..41712
                     /locus_tag="VQ547_000646"
                     /pseudo
     CDS             39016..41712
                     /locus_tag="VQ547_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(41746..>42630)
                     /locus_tag="VQ547_000647"
     CDS             complement(41746..>42630)
                     /locus_tag="VQ547_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2542538.1"
                     /translation="HQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSF
                     IAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPC
                     AKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRF
                     YRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQV
                     HPLFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRI
                     FIALNIKKERTKFVLSQA"
BASE COUNT        12939 a         7652 c         9438 g        12601 t
ORIGIN      
        1 gaaattatcg cctataatct ttcaacttcg cccaacttag aacaagtata aacaatgttg
       61 gaacaggcat tcaaagagaa gcactacgag aatacgattc tccatagtga ccaaggctgg
      121 caatatcaac acgattctta tcatcagttc ctagagagta agggaattca agcatccatg
      181 tcacgtaagg gaaacagccc agacaatggt atgatggagt ccttctttgg gattctgaaa
      241 tcggaaatgt tttacggtta tgagaagtcg tttcagtcgc ttaagcaatt ggaacaagcc
      301 attatagact atattgatta ctacaacaat aaacgaatta agataaaact aaaaggactt
      361 agccctgtgc aatacagaac taaatccttc ggataaatta attgtctaac ttttggggtg
      421 cagttcacag aactggcatt ttatttttta ggatcttgat gggttaggtt caatccccaa
      481 gggaccaaat tttcagtttt atttttgata cgagctatat tgtccttatg acgaatgata
      541 atcaaactag caagtgctaa gataatagcg atgaagagag agtcatagtt actcaggata
      601 aaaccaaaaa gtggaaagag cagaaccccg ataacagccg cgatcgatgc tgtgacacta
      661 gacagtgaaa tcatactgcc aagatagaga gctccaaaga agataatcgc aaggtagaga
      721 cagaagatag gcgcaaatcc gaaaattact ccagcactgg ttgcgacagc cttaccacct
      781 ttaaatcctg caaagatagg gaaggtatgg ccgataacag ccaaaagtcc aaagatgaga
      841 ggagaaacgc cttgtagatg aaaaataatc ggaagcagcg ttgctagggt tcctttgaaa
      901 aagtcaatca caaaggttgc cataccagct ttcttaccta aaatgcggaa ggtattggtc
      961 gttccagtgt taccagaacc atgctcgcgt agattgattt gaaagaatac ttgtccaatc
     1021 cagagaccag atggaatcga acccagcaga taggctagga ttaataaaac tattgtaatc
     1081 atactcctat tatatcatga attgggaaag aaaagcagag aatctctgct aaaattgtca
     1141 catcggagaa agaaaaattt tgcaaaatcc ttggaaaacc tgtagaatag taaagatgaa
     1201 cgaataggag gttccttgtg tcaaaaaagg aaatcaatat taacaattat aatgatgatg
     1261 ctattcaggt gctagaaggg ttggatgcgg tccgaaaacg tccagggatg tatattggat
     1321 cgaccgatgg cgctggtctt catcacctag tttgggaaat cgttgataat gcagtcgatg
     1381 aagccttgtc tgggtttggt gatcgtatcg atgtaaccat caataaagac ggtagtctaa
     1441 cggttcaaga ccatggacgt gggatgccga caggtatgca cgctatggga attccaactg
     1501 ttgaggttat ctttaccatt cttcatgccg gagggaaatt cggtcaaggt ggctataaga
     1561 catcaggtgg acttcacgga gtgggttctt ccgttgttaa cgccctttct agctggttag
     1621 aagttgaaat tacccgtgat ggcgcagttt acaagcaacg tttcgaaaat ggtggaaaac
     1681 ctgtcacgac tttgaagaaa atcggtacag cacccaagtc taaaacaggc accaaagtta
     1741 cttttatgcc tgacgcgact atattttcta cgacagattt caagtacaat accatttcag
     1801 agcgccttaa tgaatcagcc tttctcttga aaaatgtgac cttgtcttta acggacaagc
     1861 gaacagatga agcgattgag ttccactatg agaatggagt acaagatttt gtttcttatc
     1921 tcaacgaaga taaggaaatc ttgacgccag ttctttactt tgaaggggaa gacaatggtt
     1981 ttcaagtgga agtagccctc cagtacaatg acggattctc agataacatt ctatcctttg
     2041 tcaataacgt tcgcaccaag gacggtggaa cgcacgagac aggactcaag tctgccatta
     2101 ccaaggtcat gaatgactat gcacgtaaaa caggtcttct caaggaaaaa gataaaaacc
     2161 ttgaaggttc agactatcgt gagggactag cggccgttct ttctatctta gttcctgaag
     2221 aacacttgca gtttgaagga cagaccaagg ataaactagg aagcccccta gctcgcccag
     2281 ttgtggatgg aatagtggct gataagttga cctttttcct tatggaaaat ggggaattag
     2341 cttctaacct catccgcaag gctatcaagg cccgtgatgc tcgtgaagca gcacgtaagg
     2401 cgcgtgatga gagccgaaat gggaagaaaa acaagaaaga taagggcttg ttgtctggga
     2461 aattgacccc agcccaatct aagaatcctg ctaagaatga actctatcta gttgaggggg
     2521 actctgccgg tggttctgcc aaacaaggtc gtgaccgcaa gttccaggct attctacctc
     2581 ttcgtggtaa ggttatcaat acagccaagg ccaagatggc ggatatcctc aaaaatgaag
     2641 agatcaatac catgatttat accattggtg cgggtgttgg agcagacttc tctattgaag
     2701 atgccaacta tgataagatc attatcatga ccgatgcgga taccgacggt gcccatatcc
     2761 agaccttgct cttgacattt ttctaccgtt acatgcgtcc gctagtcgag gcaggtcatg
     2821 tctatattgc cctcccacct ctttacaaga tgtccaaagg taaaggaaag aaagaagaag
     2881 tggcctacgc ttggacggac ggagaactag aagaactccg taaacagttc ggtaaaggcg
     2941 ctaccctcca acgatacaaa ggacttggtg agatgaatgc ggaccagctc tgggaaacaa
     3001 ccatgaaccc agaaacacgt accctcatcc gtgtcacaat tgaagattta gcgcgcgccg
     3061 aacgccgcgt caatgttctc atgggagata aggtagaacc acgccgtaaa tggattgaag
     3121 ataatgtcaa gtttacgcta gaagaagcga cagtgtttta atgaaagaaa ataatatgtt
     3181 agtaaactgg aaattagagt cggatgtgaa tgactatgtg aaaaagcagt ttgaaaatct
     3241 tggtttgaaa aaattgcagg attattaatg aagaatctgc tatgagtgct tatctcaaag
     3301 aggcgcttaa gggagcggct aagacacaaa ctaagactaa ttttggaaaa ccagattttc
     3361 atattgaaaa atacaaacag gatagtttgg ttacttatcg taactgaaca cgggaggaat
     3421 tcccgtaaaa tatcttttac tgcataaaaa cctactctac attctttgaa aggagttgaa
     3481 cacgccctag atactgtgtg aaaaagataa attctcttgt gagtttgctt acttcaagaa
     3541 ttttctattt tcacttggta ttttatgggc tttgtatctt atgtctaaca ttcaaaacat
     3601 gtccctggag gacatcatgg gagagcgctt tggtcgctac tccaagtaca ttattcaaga
     3661 ccgggctttg ccagatattc gtgatgggtt gaagccggtt cagcgccgta ttctttattc
     3721 tatgaataag gatagcaata cttttgacaa gagctaccgt aagtcggcca agtcagtcgg
     3781 gaacatcatg gggaatttcc acccacacgg ggattcttct atctatgatg ccatggttcg
     3841 tatgtcacag aactggaaaa atcgtgagat tctagttgaa atgcacggta ataacggttc
     3901 tatggacgga gatcctcctg cggctatgcg ttatactgag gcacgtttgt ctgaaattgc
     3961 aggttacctt cttcaggata tcgagaaaaa tacagttcct tttgcatgga actttgacga
     4021 tacggagaaa gaaccaacgg tcttgccagc agcctttcca aacctcttgg tcaatggttc
     4081 gactgggatt tcggctggtt atgccacaga cattcctccc cataatttag ctgaggtcat
     4141 agatgctgca gtttacatga ttgaccaccc aactgcaaag attgataaac tcatggaatt
     4201 cttgcctgga ccagacttcc ctacaggggc tattattcag ggtcgtgatg aaatcaagaa
     4261 agcttatgag actgggaaag ggcgcgtggt tgttcgttcc aagactgaaa ttgaaaagct
     4321 aaaaggtggt aaggaacaaa tcgttattac tgagattcct tatgaaatca ataaggccaa
     4381 tctagtcaag aaaatcgatg atgttcgtgt taataacaag gtagctggga ttgctgaggt
     4441 tcgtgatgag tctgaccgtg atggtcttcg tatcgctatc gaacttaaga aagacgctaa
     4501 tactgagctt gttctcaact acttatttaa gtacaccgac ctacaaatca actacaactt
     4561 taatatggtg gcgattgaca atttcacacc tcgtcaggtt gggattgttc caatcctgtc
     4621 tagctacatc gctcaccgtc gagaagtgat tttggcgcgt tcacgctttg acaaagaaaa
     4681 ggctgagaaa cgtctccata tcgtcgaagg tttgattcgt gtgatttcga ttttggatga
     4741 agtcattgct cttatccgtg cttctgagaa taaggcggac gccaaggaaa acctcaaagt
     4801 tagctatgat tttacggaag aacaggctga ggctatcgta actttgcaac tgtaccgttt
     4861 gaccaatacc gatgtggttg tcttgcagga agaagaagca gagcttcgtg agaagattgc
     4921 tatgctggcg gctattatcg gtgatgaaag gactatgtac aatctcatga agaaagaact
     4981 tcgtgaggtc aagaagaaat ttgcaactcc tcgtttgagt tctttagaag acactgcgaa
     5041 agcaattgag attgatacag ctagtcttat cgctgaggaa gatacctacg tcagcgtgac
     5101 caaggcaggt tacatcaagc gtaccagtcc acgttccttt gcggcttcca ccttggaaga
     5161 aattggcaag cgtgatgatg accgtttgat ttttgttcaa tctgccaaga caacccagca
     5221 cctcttgatg ttcacaagtc ttggaaatgt catctacaga ccaatccatg agttggcaga
     5281 tattcgttgg aaggacatcg gagagcatct gagccaaacc atcacaaact ttgaaacgaa
     5341 tgaagaaatc ctttatgtgg aagtactgga tcagtttgac gatgcgacaa cctactttgc
     5401 agtgactcgc cttggtcaaa tcaaacgggt agagcgaaaa gaattcactc catggcggac
     5461 ctatagatct aagtctgtca agtatgctaa gctcaaagac gatacagatc agattgtagc
     5521 agtggctccg attaaactag atgatgttgt cttggttagt caaaatggtt atgccctgcg
     5581 tttcaatatc gaagaggttc cggttgtcgg tgctaaggca gcaggtgtca aggctatgaa
     5641 tttgaaagaa gatgatgtcc tccaatctgg ctttatctgt aatacttcgt ccttctacct
     5701 cttgacccag cgtggaagct tgaaacgtgt ttctattgag gaaattctag caaccagccg
     5761 tgccaaacga ggattacaag tcttgcgtga gttgaaaaac aaaccgcatc gtgtcttctt
     5821 ggcaggagca gttgcagagc aaggatttgt tggcgatttc ttcagtacgg aagtggatgt
     5881 gaacgaccaa actctgcttg tccaatccaa taaaggaaca atctatgaaa gccgattgca
     5941 agacttgaac ttgtcagaac gcactagcaa tggaagcttc atttctgaca cgatttcaga
     6001 tgaagaagtt tttgacgctt atcttcagga agtagttact gaagataaat aagtgaaatg
     6061 aagaatcagt tctaagagct ggtttttatt ggagaaattt tctgaaaatt acaaaatata
     6121 cttgctattt tagaaaaata gtgtagaata taagaaatag gtttttagaa taaggagtgg
     6181 aatatgacag taacgattga ttgggaaaac ctcggttttt cctatatgaa attaccttat
     6241 cgctatcttg ctcatttcaa aaatggacaa tgggatcaag gagagcttac agaggatgca
     6301 actttgcata tttcagagtc ttctccaagt cttcactatg gacaacaagc atttgaaggt
     6361 ttgaaagctt atcgtactaa ggatggcagt gttcaactgt tccgtcctga tgaaaatgct
     6421 aaacgtctgc aacgtacatg tgaccgtctc ttgatgccac aagttccgac agacatgttt
     6481 gtagaagctt gtaaagcagt tgtccgtgcg aatgaagaat acgtaccacc atacggaaca
     6541 ggtggaacct tatatcttcg ccctcttttg attggtgtcg gagatattat cggggtaaaa
     6601 ccggcagaag agtacatttt caccatcttt gctatgccag ttggaaatta ctttaaaggt
     6661 ggtttggtcc caaccaactt cttgattcag gatgagtacg accgtgcagc accaaatggt
     6721 acaggtgcgg ctaaggttgg tggaaactat gctgcaagtc tcttaccagg aaaaatggcc
     6781 aagtcacgtc atttctcaga tgttatctat ctggacccat caactcatac aaagattgaa
     6841 gaagtcggat cagctaactt ctttggaatt acagctgata atgaatttgt aacaccattg
     6901 agtccatcta tcttgccatc tattaccaag tattccttgc tttatttggc agaacatcgc
     6961 ttgggattaa ctcctattga gggtgatgtt ccaattgata atcttgaccg ttttgtagag
     7021 gcaggtgcct gtggtacagc agcggttatt tctccaattg gaggtattca acatggtgat
     7081 gatttccatg tattctatag tgaaacagaa gtaggtcctg tgacgcgtaa attatataat
     7141 gaattgacgg gtattcagtt tggcgatatt gaagcgccag aaggttggat tgtaaaagta
     7201 gattaaaata aaccaaagga gattttttat gaaatagaaa aagtggctct taacagcagg
     7261 agtggtcctg agcacgtcag ctattttagt ggcttgtgga aaaactgata aagaagcaga
     7321 tgcaccgaca acattttctt atgtctatgc agtagatcca gcatcattgg gctacagtat
     7381 agcgactcga acatcgagga cagacgttat tggaaatgtt attgatggtt tgatggaaaa
     7441 tgataaatac ggcaatgttg ctccttctca aaaagactat gatttgaaca gtacaggatg
     7501 ggctccaagc tatcaagatc cagcgtctta cttgaatatt atggatccaa aatctggttc
     7561 tgacatgaaa caccttggca ttacgaaagg aaaagataag gatgttgtag ctaaacctgg
     7621 tttggataaa tataagaaat tgttagaaga tgctgtttct gagaccactg acctagagaa
     7681 gagatatgaa aaatatgcca aagctcaagc ttggtcgaca gatagttcat tattgatgcc
     7741 aacagcttca tctggtggtt ttccagttgt aagtaacgta gtaccattct caaaaccata
     7801 ctcacaagtt ggtattaagg gggaaccata tatctttaaa ggaatgaaat tgcaaaaaga
     7861 tattgttaca acaaaagaat ataacgaggt ttttaaaaaa tggcaaaaag aaaaattgga
     7921 atccaatagc aaataccaaa aagaactaga aaaatacatt aaataaggaa tggtattgat
     7981 cttgataaaa tttttaaaat actgtcattt tgaatataaa ggagtttgat atggagtgga
     8041 ttagattaat aggaatagca atcattgttg tgggttttat tttaaaattt gatacaattg
     8101 caacagtagt cttagctggt ttggttacag ctttagtttc aggtgtttct ctcgttgaat
     8161 ttttggagat tttgggaaaa gaatttagca atcagcgagt gctcacgatt tttatggtta
     8221 ccttgcctct tgtggggctg tcagaaacct ttggactcaa gcaacgatca atcgatttga
     8281 ttcgaaagat taaaggtctg acagttggaa acttctatac agtttatttc tttattcgag
     8341 agttagctgg tttcttttca attcgtctag gaggacaccc tcagtttgtc agacctttgg
     8401 ttcaacctat gggagaagca gctgcagagt ctcaattagg tagaaagtta acagaggttg
     8461 aagatgagac aataaaagcg cgtgcggctg cgaatgaaaa ttttggaaat ttctttgctc
     8521 aaaatacgtt tgtaggtgct gggggagtcc tcttgatagg gggaacatta gatcagttag
     8581 gctatgaaag caattatgca gggattgctt ctacatctat tattgttgct gttataacac
     8641 ttattgtagt ggggatttac aattatttat ttgataaaaa attgatatca aaaaagacta
     8701 ggggaggaga acaaaaatga cagagttggc aaagcaacta ttagagttga cctatattgt
     8761 gattggttgt caatttctcc atacagccta ttgtagttat aaagataaaa caaacccagt
     8821 tcgacttggg acatctgcat tttggactct attgtctatt acgtttatag gtggttccta
     8881 tatgccaaat atgagtattg gtattattgt aatcctatta tcgctgttaa cattgtttaa
     8941 gcaagtccgt atcggaacct tgccatcctt agatgaaatg aaagccaata ttgaatctaa
     9001 caggttgaaa aataaaattt ttattccagt tatgctgatg gcaatacttg cgttggtctt
     9061 agcgcaaatg attccagaat ttagcaagat ttcgattagc cttgccgcct tgtttgctac
     9121 aatttctgtt cttgtgatta ccaatagtca ccctaagagt ctgttatcag aaaataatcg
     9181 aatgactcag caagtttcaa caagtgggat tgttcctcaa ttattagggg ctttgggggc
     9241 tatttttact gtagcaggtg ttggtgatgt tatctctcat ctgattagcg gtattgttcc
     9301 ttcagatagt cgctttatag gagttttggc ttatgttctt ggaatggttc tattcacaat
     9361 gattatggga aatgcttttg cagcattcac cgttattaca gcaggtgttg gagttccctt
     9421 tgtatttgct ctgggagcta atccaattgt ggctggtgct cttgccatga cagcaggtta
     9481 ttgtgggacc ttattgaccc caatggctgc taattttaac gctctaccag cagcattgat
     9541 ggatatgaaa gatcagaatg gcgttataaa ggctcaagca ggtgttgctc tagtaatgat
     9601 tgttattcac atattcttaa tgtactttct cgcattttag taaaggaaaa taaaatgaaa
     9661 atattggtta caggttttaa tccttttgga ggtgaaaaga ttaatccagc tttggaggct
     9721 gtaaaattat taccatctga gattaatggg gctgaagttc gctgggtaga aattccaacg
     9781 gttttttata agtcgtcaga agttttagag gcagaaatat tacgatatca accagatgct
     9841 gtactttgta ttggacaagc aggcggcagg accggcttaa cacctgaacg agtggctatt
     9901 aatcaagatg atgctcgcat acctgataac gaaggcaatc aaccaattga tacaccgatt
     9961 cgtattgatg gagcatcggc ctattttagt agtttaccta tcaaagcgat ggtacaagct
    10021 atcaaaaaac agggacttcc ggcagttgta tccaatagtg caggaacctt tgtttgcaat
    10081 catttgatgt accaagctct ttatttagtg gataaaaaat tccctaatat gagagcaggt
    10141 ttcatgcata ttccatatat gatggaacaa gtagtaaata agccgaatac tgcaggaatg
    10201 agtctatgtg atattgtaag aggcatagag gtagctattg aagctattgt agactacaaa
    10261 gataaggatt tgcagttagt aggcggtgag actcactgat aacctaaaaa ggatagtcaa
    10321 ttatgcttgt ttactaacta ttaactatgc taaatcaatt gaggttgttt acataaaact
    10381 ctatatcaga gaagcctgat atagagtttt ttcttgctag ttttaggatt ttcttgtaaa
    10441 atagaaaaag tgaagagagg tatgaaatga gcaagaaaga taaaaaaatc gaaattcaag
    10501 tagcggatgc caaagttaat gttggtaaag acagttttga aggttataca ttgactatcg
    10561 gtaaaaaagt tatcggagaa attgccgaat tagacggaca atttgccatt ataaagaatg
    10621 ggaatgtcga tagtttttat aaaaaattgg aaaaagctgt ggaaattttg attgaaaatt
    10681 ataatttagc aaaataagtc ttgttttttt gaaattttca tgatataata gtccatgttg
    10741 attgtaggag agatagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
    10801 tcgggggttc gaatccctct ctctccattt cattaatggg gtatagccaa gcggtaaggc
    10861 aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagtt cttaggtaat
    10921 aatcaagata aaaagcaaaa tatcttaggg tattttattt ttataattga aagacgtgaa
    10981 tgatatgaac atgtccttgc gggtgcttag gaaaaaaatt ataagtatgt caagtttaag
    11041 aaaaacttga ttgttggagg attttttaga tgaacgaatt tgaagatttg ctaaatagcg
    11101 ttagtcaagt tgagactggt gatgttgtta gtgctgaagt attgacagtt gatgcgactc
    11161 aagctaacgt tgcaatctct ggaactggtg ttgaaggtgt cttgactctt cgcgaattga
    11221 caaacgatcg tgatgcagat atcaatgact ttgttaaagt aggagaagta ttggatgttc
    11281 ttgtacttcg tcaagtagtt ggtaaagata ctgatacagt tacatacctt gtatctaaaa
    11341 aacgccttga agctcgcaaa gcatgggaca aacttgttgg tcgcgaagaa gaagttgtta
    11401 ctgttaaagg aacgcgtgcc gttaaaggtg gactttcagt agaatttgaa ggtgttcgtg
    11461 gatttatccc agcttcaatg ttggatactc gtttcgtacg taacgctgag cgttttgtag
    11521 gtcaagaatt tgatactaaa atcaaagaag ttaacgctaa agaaaaccgc ttcatccttt
    11581 cacgtcgtga agttgttgaa gcagctactg cagcagctcg cgctgaagta ttcggtaaat
    11641 tggctgttgg tgatgttgta actggtaaag ttgctcgtat cacaagcttc ggcgctttca
    11701 tcgaccttgg tggtgttgac ggattggttc acttgactga attgtcacat gaacgtaacg
    11761 tatcaccaaa atcagttgta actgttggtg aagaaattga agtgaaaatc cttgatctta
    11821 acgaagaaga aggacgtgta tcactttcac ttaaagcaac agtaccagga ccatgggatg
    11881 gcgttgagca aaaattggct aaaggtgatg tagtagaagg aacagttaaa cgtttgactg
    11941 acttcggtgc atttgttgaa gtattgccag gtatcgatgg acttgttcac gtatcacaaa
    12001 tttcacacaa acggattgaa aatccaaaag aagctcttaa agttggtcaa gaagttcaag
    12061 ttaaagttct tgaagttaac gcagatgcag aacgcgtgtc actttctatt aaagctcttg
    12121 aagaacgtcc agcccaagaa gaaggacaaa aagaagaaaa acgtgctgct cgtccacgtc
    12181 gtccaagacg tcaagaaaag cgtgatttcg aacttccaga aacacaaaca ggattttcaa
    12241 tggctgattt gtttggtgat atcgaacttt aatcaaattg aaaattcaca aaatcctttg
    12301 tttactaaac aagggatttt tcttttgtct ctgctccttt tttgatataa tagttctatg
    12361 ttaaaatcag aaaaacaatc acgttatcaa atgttaaatg aagaattgtc cttcctattg
    12421 gaaggcgaaa ccaatgtttt ggctaatctt tccaacgcca gtgctcttat aaaatcacgt
    12481 tttcctaata ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt ggttttaggt
    12541 cccttccaag gaggtgtttc ctgcatccgt attgcactag gcaagggtgt ttgtggtgag
    12601 gcagctcact ttcaggaaac tgttattgtt ggagatgtga cgacctatct caactatatt
    12661 tcttgtgata gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta
    12721 cttggagttc tggatctgga ttcttcagag attgaggatt acgatgctat ggatcgagat
    12781 tatttggaac aatttgtcgc tattttgctt gaaaagacaa catgggactt tacgatgttt
    12841 gaggaaaaat cttaatgtat caagcacttt atcgaaaata tagaagtcaa aacttctccc
    12901 agttagttgg tcaagaagtt gtggctaaga ctcttaaaca agcggtggag caagagaaaa
    12961 taagtcacgc ttatcttttt tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa
    13021 tctttgccaa ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc aataactgct
    13081 atatttgtca agcagtgacg gacggtagtt tagaagatgt cattgaaatg gatgcagctt
    13141 ctaataatgg ggtagatgaa attcgcgaaa ttcgtgataa atctacctat gcgcctagcc
    13201 ttgctcgtta taaggtttat atcatagatg aggttcacat gctgtctaca ggggctttta
    13261 atgccctcct aaagacgctg gaagaaccaa cacagaatgt agtctttatt ttggccacta
    13321 ctgaattaca caagattcct gctactattc tatcccgtgt gcaacgtttt gagtttaaat
    13381 caattaagac acaggatatt aaggaacata ttcactatat cttagaaaaa gaaaatatca
    13441 gttctgaacc agaggctgtg gaaatcattg ccagacgggc ggaaggtgga atgcgggacg
    13501 ccttgtctat tttggatcaa gccctgagtt tgacacaggg aaatgagctg acgactgcta
    13561 tctctgaaga aattactggc actattagcc tatcagcctt ggatgattat gtggcggcct
    13621 tgtctcaaca ggatgttccc aaagctttgt cttgcttgaa tcttcttttt gacaatggta
    13681 agagcatgac tcgttttgtg accgatcttt tgcactattt aagagacttg ttaattgttc
    13741 aaacaggggg agaaaatact catcatagtt cagtctttgt agaaaatttg gcacttcctc
    13801 aaaaaaatct gtttgaaatg attcgcttag caacagtgag tttagcagat attaagtcta
    13861 gtttgcagcc caagatttat gctgaaatga tgaccgtccg tttggcggaa atcaagcccg
    13921 aaccagctct atcaggagcg gttgaaaatg aaattgctac gctgagacag gaagttgccc
    13981 gtctcaaaca agagctttct aatgtaggtg cggttcctaa acaagttgca ccagctccta
    14041 gtcgaccagc tacgggcaaa acagtctatc gtgtcgatcg caataaagtg caatctatct
    14101 tacaagaggc cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg
    14161 cctggggaga ggtaattgaa agtctaggtg ggccggacaa ggctctgcta gttggttctc
    14221 aaccggttgc tgccaatgaa caccatgcta ttcttgcttt tgagtctaac ttcaatgctg
    14281 gtcaaactat gaaacgagac aatctcaata ccatgtttgg caatatcctc agtcaggcgg
    14341 caggtttttc acctgagatt ttagctattt ccatggagga atggaaagaa gttcgcgcag
    14401 ccttttcagc caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa agcctgattc
    14461 cagaaggatt tgaatttttg gctgataaag tgaaggtaga ggaagactaa agaaagattt
    14521 cgtgatacaa taagtttatg aataaacaac aatttattat tatggcgctg tttacagctg
    14581 ctgagaccta ttttttcaat gaagcctgga tgactggccg ctatattatg gcagcctttt
    14641 gggcaatttt actctttaga aatttccgag tcagttatgt gatgggcaaa atcgttgatg
    14701 tcatcgatca gcattttaat aggaaagact agccctcagc ttccagacaa aatcaaagcc
    14761 ttttaggctt ttttttgtta tactagaaaa gtatatttat agaatttttg ctctatttct
    14821 ggggaaatca gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat
    14881 catgtcagta ttagagatca aagatcttca cgttgagatt gaaggaaaag aaattttaaa
    14941 aggggttaac ctgaccctga aaacaggaga aattgccgct atcatgggac caaatggtac
    15001 aggtaaatcg actctttctg ccgctatcat gggaaatcca aactatgaag taactaaagg
    15061 tgaagttttg tttgatggcg taaacatcct tgagttggaa gtggatgagc gtgcgcgtat
    15121 gggacttttc cttgctatgc aatacccatc agaaatccct ggaattacca atgctgagtt
    15181 tcttcgtgcc gctatgaatg cgggtaaaga agatgatgag aagatttcag ttcgtgagtt
    15241 tattactagg ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa tggcagagcg
    15301 ttacctcaac gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt
    15361 gatgttggag ccaacatttg ctcttttgga cgagattgac tcaggtcttg atattgacgc
    15421 tcttaaagtt gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat
    15481 catcactcac taccaacgtc ttttgaacta tatcacacct gatgtggtac acgtgatgat
    15541 ggaaggtcgt gttgtccttt ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg
    15601 atacgcaaaa ttagctgaag aacttggcta cgactacaag gaagaattgt aatttcctcg
    15661 tatcttttag gagaagtaaa tgactagaga aaatattaaa cttttttcag aaatgcacgc
    15721 tgaaccaagc tggttggctg atctccgtca aaaagctttt gacaagattg agactttgga
    15781 attaccagtt attgagcgtg tcaaattcca ccgttggaat ctgggtgatg gaacgattac
    15841 agaaaatgag ccatcagcaa atgttccaga tttcacagct ttagatcatc acttgaagtt
    15901 ggtgcaagta ggaactcaaa ctgttttcga acaaactcca gttgagttag ctgaacaggg
    15961 tgttgtcttc acagactttc actcagcttt agaagaaatt ccagagctga tcgaagaatt
    16021 cttcatgtca tctgttaagt atgatgatga caagttggcg gcttaccaca cagcttactt
    16081 taacagtggt gctgtactct atattccaga taacgtagaa atcacagagc caattgaagg
    16141 aattttctac caagatagcg atagcaatgt gccgtttaac aagcatatta tgattatcgc
    16201 tggtaaaaat tctaagatta attatctgga gcgtttagag tcacgcggtg aaggaagtgc
    16261 caaagcaact gctaatatca cagtagaagt gattgcacgt tcaggtgcgc aagtcaagtt
    16321 tgctgctatc gaccgtctag gtgaaaacgt cactgcctac attagccgtc gtggtaaatt
    16381 aggcaacgat gcaagtattg actgggctat cggtgtcatg aacgaaggaa atgtcgttgc
    16441 tgattttgat agtgacttga ttggtaatgg tagctatgct gacctcaagg ttgtagctct
    16501 ttcaagtggt cgtcaggtac aagggattga tactcgtgta actaactatg gctgcaactc
    16561 tatcggaaat atcctacaac atggggttat ccttgaaaaa gcaactttga ctttcaatgg
    16621 tatcggccac atcatcaagg gtgctaaggg agcagatgcc caacaagaga gccgtgttct
    16681 catgctttca gaccaagcgc gttcagatgc taacccaatt cttttgattg atgaaaatga
    16741 tgtcactgca ggacacgcag cgtctatcgg acaagttgat ccagaagaca tgtattacct
    16801 catgagtcgt ggattggata aggcaactgc agagcgtttg gttgttcgtg gtttccttgg
    16861 atctgttatc gtggagattc cagtcaagga agttcgtgat gaaatgattg caactatcga
    16921 agagaaattg tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg attcgcaagg
    16981 attttccaat tttagatcag attgtcaatg atgaacctct ggtctatctg gacaatgctg
    17041 cgacgacaca aaaaccacta gtagttctga aagctattaa cagttactat gagcaggaca
    17101 atgccaatgt tcaccgtggt gtccatacct tagcggaacg agcgacagct tcttatgaag
    17161 ctgctcgtga aaccattcgt aagtttatta atgcaggctc tacaaaggaa gttctcttta
    17221 ccagaggaac gacaaccagc cttaactggg tggcacgctt tgctgaggaa attctcactg
    17281 agggagacca ggtcttgatt tcagtaatgg aacaccattc taatatcatt ccatggcagg
    17341 aagcttgtcg aaagactgga gcagagcttg tctatgtcta tcttaaagac ggtgccttgg
    17401 atatggagga tttgcgagct aaattgactg ataaggttaa atttgtttcc ctagctcatg
    17461 cctccaatgt tcttggtgtg gtcaatccga tcaaggaaat cactcaatta gcccaccaag
    17521 ttggggcaat catggtagtg gatggtgctc aatctacacc tcatatgaag attgatgtcc
    17581 aggacttgga tctggacttt ttcgcctttt cgggtcacaa gatggctggt ccgactggta
    17641 tcggtgtcct ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta gaatttggcg
    17701 gcgagatgat tgattttgtc tacgagcaat ccgctagttg gaaggaattg ccttggaaat
    17761 ttgaggctgg aacgccaaat atggcaggag ctattggact tgcgactgca gttgattatc
    17821 tggaaaagat tggtatggat gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct
    17881 atccaaaact gcaggcaatt gagggattga ccatttacgg ttctcaggat ttggctcaac
    17941 gttcgggtgt tattgccttt aacctaggtg atctccatcc tcacgatctt gcgacggctc
    18001 tggattatga aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt
    18061 atttggaagt cccagcatca gctcgtgcaa gtttttatat ctataatacc aaggcagatt
    18121 gcgacaaact agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc actttctaaa
    18181 ctagatagcc tttatatggc agtggtagca gaccattcga aaaatccaca tcaccaaggg
    18241 aagttagaag acgctgagca aatcagtctc aacaatccga cttgtgggga tgtcatcaac
    18301 ctctctgtca agtttgatgc agaggaccgt ttggaagata ttgcttttct aaattcagga
    18361 tgcacgattt caactgcttc tgctagtatg atgacagatg ccgttttagg aaaaaccaaa
    18421 caagaaattt tagaactggc gactattttt tctgaaatgg ttcaagggca aaaagatgag
    18481 cgtcaagacc aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga
    18541 atcaagtgtg caaccctagc ttggaatgcc cttaagaaaa caattgaaaa tcaagaaaaa
    18601 cagtaagaca agtttctttt gtcttatgaa ttattagaaa tgaagaaagg atattatggc
    18661 tgaagaaaga gtagaaccaa aaccaattga ccttggtgaa tataaatttg gtttccatga
    18721 cgatgtagag cctgtcttat cgacaggaaa aggactcaac gaaggtgtta ttcgtgaatt
    18781 atctgctgct aagggtgagc ctgagtggat gttggagttc cgtttgaagt cttatgaaac
    18841 cttcaaaaaa atgcccatgc aaacttgggg agcagacttg tcagagattg actttgatga
    18901 cttaatctac taccaaaaac catctgacaa accagcccgt tcttgggatg atgtacctga
    18961 aaagattaaa gaaacctttg aacgtatcgg gattccagaa gctgaacgtg cttatttagc
    19021 aggggcttct gcccagtacg agtcagaagt ggtttaccac aacatgaagg aagagttcca
    19081 aaaattaggt attatcttta cagatacaga ttccgcactc aaggaatacc cagacttatt
    19141 taaacaatac tttgcgaagt tggtaccgcc gacagataac aagttggcag ccctcaactc
    19201 agcagtatgg tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg tagatattcc
    19261 acttcaaact tatttccgta tcaataacga aaatataggt cagttcgaac gtaccttgat
    19321 tatcgttgat gagggagcaa gcgtccacta cgtagaagga tgtacagcac caacatattc
    19381 aagcaatagc ttgcacgctg ccattgtaga aatttttgct ttggacggag cttatatgcg
    19441 ttatacaact atccaaaact ggtctgataa cgtctataac ttggtaacaa agcgtgctaa
    19501 ggctcaaaag gatgccactg ttgagtggat tgatggaaac ttgggtgcca aaacgactat
    19561 gaaatatcca tctgtttatc ttgatggaga aggagcgcgt ggtaccatgc tctctatcgc
    19621 ctttgctaat gcagggcaac accaagacac gggtgctaag atgattcaca atgctccaca
    19681 taccagctcg tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg ttgactaccg
    19741 tggacaagtc acctttaaca agaactctaa gaaatctgtt tcccacattg aatgtgatac
    19801 cattatcatg gatgacttgt cagcatcaga tactattcca tttaatgaaa ttcacaactc
    19861 gcaagtggct ttggaacacg aagccaaagt atctaagatt tcagaagagc aattgtatta
    19921 tctcatgagc cgtggattgt cagaatctga ggcaactgaa atgattgtca tgggatttgt
    19981 agaacccttt acaaaagaac ttccaatgga atacgcagtt gagctgaacc gcttgattag
    20041 ctatgaaatg gagggatcag ttggataaaa tttgatttta tactcttcga aaatctcttc
    20101 aaaccacgtc agcatcgcct taccgtatgt atggttactg acttcgtcag tttcatctac
    20161 aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttatt ctttgatttt
    20221 gagtattaga tttactcaaa atcaaggatt ttgaagatga acttgtatca aaaaatcgcg
    20281 gtttaaaatc gcgatttttt ataatttctc gttaacaaag cggacaaact gattccacca
    20341 aacttttaag aagaaggctt tttcaatttt cttgtctgct accatttcga aactagggcg
    20401 ctctgtggtg atgtaacctt gaccaatcaa gtccttgtct tcataagtca aatggccaac
    20461 cactgttcca gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga attgaacaga
    20521 ttgggaagat tgattcccaa cacgttcgat tagatagata tcctctggag ccactgcagt
    20581 tactgtatct tcttttccat cttgtacagg ggctttgcta tcttgatagg catcgccttg
    20641 ttgaacgatt ttgcgaagtg taaatgtaga agaaatataa tccattaggg aagatgtagc
    20701 tgtaaatcga gcgtaaggat tattgtcttg atgatctgca tttaaaacaa ctgtgatgac
    20761 tctcatgcct ttttcgacag tagtaccaac aaaagactct ccagccttat ctgttgttcc
    20821 tgtttttagc ccatcaaaac caccacggta agcaggcata ccttctaaca tgtagttggt
    20881 tgaagtgatt gtcatcccag caaaagtaga agaaggtttt ttggtgattt ctaagacttg
    20941 tgggtatttt ttgatgaggt tgcgagcaac gatagcgaca tcataagcac taagcttatt
    21001 ttcctcatct tttttagaac ctgggtaaat gttatcccct agagtttcat tgttaagacc
    21061 tgtcgtattg acaacagtgg catcctgaat tccccattcc aagagttttg cccgcatcat
    21121 atcgatgaaa tctttttctg agccagcaat tttctcagct agggcaatag cggcgctgtt
    21181 ggcactagat accagagttg cttcaagcaa ctcttcgaca gtataattac gggcctccat
    21241 aggaatatta ctggcttcag aatttgtcgt caattgataa ggataatcag aaatatctac
    21301 aggagtggag agggtaatac ttccgttttc caaagcttca tagaccagat aagcagtaat
    21361 caattttgtt atggaagcaa tttcgacagg ttgcgttgca tccttctcat agagaatttt
    21421 accagtattt gcctcaacag caatcgcatg tttagcggca atggtaaaat cttgagcaac
    21481 agcagtagaa gcacccccta aaagagagac agttaacaaa gttaaaaata tttttttcat
    21541 agtagtctta ttctatcata aagaaaaaaa atattcttgc tttaataatt catctgttaa
    21601 gctttttgaa aatatggtaa aataaagtga gggaggtaac tcatgtttcg tagaaataaa
    21661 ttattttttt ggaccacaga aattttactc ttaaccatca tcttttacct atggagacag
    21721 atggggtctt tgattaaccc ttttgttagc gtgcttaata caattatgat tccattttta
    21781 ttagggggct ttctttatta tttgacaaac cctattgtta ctttcttaaa taaagtctgt
    21841 aaactcaatc gtttgcttgg tattttaatt accttgtgta ctttggtctg gggaatggtc
    21901 ataggtgttg tctatctctt acctattttg attaatcagt tatctagttt gattatatct
    21961 agtcaaacta tttatagtcg agtacaagac ttaatcatag acttatctaa ttatcctgcg
    22021 ctccagaatt tggatgtaga agctacaatt cagcagttaa acttatccta tgttgatatt
    22081 cttcaaaata tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc agctcttatc
    22141 agtactgttt tgattttgat tatgactcca gtttttttgg tttatttctt attagatgga
    22201 cataaattct tgcccatgct tgaaagaacg attctaaaga gggatcgctt gcatattgca
    22261 ggcttattaa agaatttaaa tgcgacgatt gctcgctata ttagtggagt ttcgattgac
    22321 gcaatcatta taggttgttt ggcttatatt ggctatagta ttattggttt aaaatatgct
    22381 ttagtttttg ccattttttc tggtgtagcc aatttaattc cttatgtggg gccaagtatt
    22441 ggtttgattc ctatgatcat cgcaaatata ttcactgatc cccatagact gctgattgca
    22501 gtgatttata tgcttgttgt tcagcaggta gatggcaata tcttatatcc tcgaatcgta
    22561 ggaagtgtta tgaaggttca tccaatcacg attttagttt tacttttgtt gtcaagcaat
    22621 atctatggtg tagttggaat gattgtcgca gtgccaacct attctatctt gaaagaaatt
    22681 tctaagttct tatcccgttt gtatgaaaat cataaaataa tgaaagaacg agaaagagaa
    22741 ttagctaagt aaaagtcagg agaaccctga tttttcttta ctggaagtgg cctttagatt
    22801 agaagactga aaataagtta aagtcttaaa ctaattttca cagctaagaa tagtagaagt
    22861 taatctgata aaaatcgaaa aaaccagtgg aattctgtgt cagggtaagt tccactggtt
    22921 ttcatagtct attaaagttc gaatgaaacc tatttatagt agattgaaac tagaatagta
    22981 cacctctaat tctaaaacat tgttagaaat cgatttgact gtcctgatct attcgttcta
    23041 ttcttatttc attttactat attttggtgc aataagtgaa aagtagtccg aataatataa
    23101 ggattgattt tatagttttt aaactcaaat gaattgaaat aaagagagta cgaaaattct
    23161 catctgaaag tattttagaa taattctctt cgtgaatttc ttcaaaacag atagcttcat
    23221 cttaggtatg tgatttcttt ttgcattttt gagttagata aggtataatg gttttattgt
    23281 cttttggggt cgttacggat tcgacaggca ttatgaggca tattttgcga ctcgtgtggc
    23341 gacgtaaacg ctcagttaaa tataactgca aaaaataaca cttcttacgc tctagctgcc
    23401 taaaaaccag caggcgtgac ccgatttgga ttgctcgtgt tcaatgacag gtcttattat
    23461 tagcgagata cgattaagcc ttgtctagcg gtttgataag agattgatag actcgcagtt
    23521 tctagacttg agttatgtgt cgaggggctg ttaaaataat acataaccta tggttgtaga
    23581 caaatatgtt ggcaggtgtt tggacgtggg ttcgactccc accggctcca ttattccttt
    23641 gcattctttt gcattccttg gtaaaacgtt gttaaatcaa cgttttttat ttttatcttt
    23701 ggtattcctt tgcattcttt tgctaaaaag ggagtcacaa acagacccta ttttaaaaaa
    23761 aggatagaaa aaaggataca acatttgtcg catcctaaaa ataatctttt ttccacggaa
    23821 gacatgggat tcgaacccac gcacgctatt acacgcctac cgcgtttcca acacggcctc
    23881 ttaagcctct tgagtaatct tccaatactt actcaaatag tctaccataa aggctcttat
    23941 cttgcaataa aaattctaga aataagaaaa atgatagatt ttgaaagaaa atgataaaaa
    24001 atgcttgact tcaaaagaaa gtatgataga atgaatagtg taaacgataa caggaggtga
    24061 ttcggtgtta aaaacagagc ggaagcaact gattttagag gagttaaatc aacatcatgt
    24121 agtttctcta gaaaaattag ttagtttgct agaaacgtca gaatcaacgg ttcgaagaga
    24181 cttggatgag ttggaagcgg aaaacaagct tcgtcgtgtg catggtggag cagaactccc
    24241 ccactcctta caggaagaag aaaccattca agaaaaatct gtcaaaaacc ttcaagaaaa
    24301 gaagttgctg gctcagaaag cagcctctct cattaaagaa aaagatgtca tctttatcga
    24361 tgctggaaca acaactgctt ttttgattca tgaattggtc aataagaata ttacagttgt
    24421 gaccaactcc attcaccatg ccgctcagtt ggttgaaaag cagattccaa ctgtcatggt
    24481 tggaggaaac gtcaagacgg cgacagatgc tagtatcggt ggcgttgctc ttaaccagat
    24541 taaccaattg cactttgacc gtgcctttat cggaatgaat ggtgttgacg atggctatta
    24601 tacgactcct gatatggagg agggagctgt gaaaagagct attttggaga atgccaagca
    24661 gacctacgtc ttggtggatt cgtcaaaaat tggacaaact tgctttgcca aggtagcacc
    24721 actcaaacgc gctatcgtta tcactagtca agggcatgag ctcttgcagg ttattaagga
    24781 gaaaacggag gtaatagaag tatgatttat acagtcacac tcaatccatc cattgactat
    24841 atcgttcgtt tggaccaagt caaagttggt agtgtaaatc gtatggacag tgatgataag
    24901 tttgctggtg ggaaaggaat caatgtcagc cgtgtcttga aacgtttgaa tataccaaat
    24961 acagcgacgg gatttatcgg tggctttact ggtaaattta tcacagatac tttagcagag
    25021 gaagaaatcg agacacgttt tgtccaggtg gcagaagata ctcgtatcaa tgttaaaatc
    25081 aaagcagacc aagaaacaga aatcaacgga acgggtccaa ctgttgaatc ggttcagcta
    25141 gaagaattga aagctatttt atctagtctg acagcagaag atacagttgt ctttgcaggt
    25201 tcaagtgcta aaaatctagg caatgttatc tataaggatt tgatttcctt gacgcgccag
    25261 actggtgcgc aagtggtctg tgactttgaa ggacagacct taattgatag tttggactac
    25321 cagcctcttc ttgtaaaacc aaacaatcat gaacttggag cgatttttgg ggttaaactc
    25381 gaaagtttag atgaaattga gaaatacgct cgtgagttac tggctaaggg tgctcaaaat
    25441 gttattatct ctatggctgg tgatggtgcc cttcttgtca catctgaggg agcttacttc
    25501 gctaaaccaa tcaaaggaac agtcaaaaat tcagttggag ctggtgattc tatggttgct
    25561 ggattcacag gtgaatttgt caaatcaaaa gacgtagtag aagccttcaa atggggagtg
    25621 gcttgcggaa cggcaactac cttctcagat gacttggcaa cggcggaatt tattaaagaa
    25681 acatatggaa aagttgaggt agaaaaacga tgaaaattca agacctattg agaaaagatg
    25741 tcatgttgct agatttgcag gcaactgaaa aaacagctgt catcgacgag atgattaaaa
    25801 atttgacaga ccacggttat gtaacagatt ttgaaacatt taaagaagga attttggcgc
    25861 gtgaagcttt gacttctact ggtttgggtg atggaatcgc aatgcctcac agcaaaaacg
    25921 ctgctgtcaa agaagcgaca gttctatttg ctaagtcaaa taagggtgtt gactacgaga
    25981 gcttggatgg acaagcaact gacctcttct tcatgattgc agctccagaa ggtgccaatg
    26041 atactcactt ggcagccttg gcagaattgt ctcaatactt gatgaaagac ggttttgcag
    26101 acaaacttcg tcaagcaaca tctgcagacc aagttatcga actttttgac caagcttcag
    26161 aaaaaactga ggaacttgtt caagcacctg ctaatgactc tggtgacttt atcgtagctg
    26221 ttacagcttg tacaacaggt attgcccaca cttacatggc ccaagaagcc cttcaaaaag
    26281 tagctgctga aatgggggtt ggtatcaagg tcgaaaccaa cggtgctagc ggtgttggaa
    26341 atcaactaac tgcagaagat atccgtaagg ctaaagctat tatcattgca gcagacaagg
    26401 ccgttgaaat ggatcgattt gatggaaaac cattgatcaa tcgtccagtt gctgacggta
    26461 tccgtaagac agaagagcta attaacttgg ctctttcagg agatactgaa gtctaccgtg
    26521 ccgctaatgg tgccaaagct gcaacagcct ctaacgaaaa acaaagcctt ggtggtgcct
    26581 tgtacaaaca cttgatgagt ggtgtatctc aaatgttacc attcgttatc ggtggtggta
    26641 tcatgattgc ccttgccttc ttgattgacg gtgctttggg tgttccaaat gaaaaccttg
    26701 gcaatcttgg ttcttaccat gagttagctt ctatgttcat gaaaattggt ggagctgcct
    26761 ttggtttgat gcttccagtc tttgcgggtt atgttgccta ctctattgct gaaaaaccgg
    26821 gtttggtagc aggtttcgtg gctggtgcta ttgccaaaga aggttttgcc tttggtaaaa
    26881 ttccttatgc cgcaggtggt gaagcaactt caactcttgc aggtgtctca tctggtttcc
    26941 taggtgccct tgttggtgga tttatcgcag gtgccttggt tcttgccatc aagaaatacg
    27001 ttaaagttcc tcgttcactc gaaggtgcta aatcaatcct tctattgcca cttcttggaa
    27061 caatcttgac aggatttgtt atgctagctg tgaatatccc aatggctgca atcaacactg
    27121 ctatgaatga cttcctaggc ggtcttggag gaggttcagc tgtccttctt ggtatcgtcc
    27181 ttggtggaat gatggctgtt gacatgggtg gaccagttaa taaagcagct tatgtctttg
    27241 gtacaggtac gcttgcagca actgtttctt caggtggttc tgtagccatg gcagcagtta
    27301 tggctggagg aatggtgcca ccacttgcaa tctttgtcgc aactcttctt ttcaaagata
    27361 aatttactaa ggaagaacgt aactctggtt tgacaaacat catcatgggc ttgtcattta
    27421 tcactgaggg agcgattcca tttggtgccg ctgacccagc tcgtgcgatt ccaagcttca
    27481 tccttggttc agcagtagca ggtggactcg ttggtcttac tggtatcaaa ctcatggcgc
    27541 cacacggagg aatcttcgtt atcgccctta cttcaaatgc tctcctttac ctcgtttctg
    27601 tcttggtagg agcaatcgta agtggtgtgg tttatggtta cctacgcaaa ccacaagcat
    27661 aaaaaataga aaaatgaaaa gattggaccg tttggtgcag tctttttctc ttcccgaaat
    27721 gcctgtgaaa tatggtataa tagaagaatg gcaaacaaga atacaagtac aacaagacgg
    27781 agaccgtcta aagcagaact ggaaagaaaa gaagcgattc aacgaatgtt gatttcgtta
    27841 ggaattgcga ttttattgat tttcgcagcc ttcaaattag gggctgcagg tataaccctt
    27901 tataatttaa ttcgcttgct agtgggtagc ctagcttatc tggcgatatt cggcctatta
    27961 atctatctct tctttttcaa gtggatacga aaacaggaag gactcttatc tggctttttc
    28021 accatatttg ctggcttact cttgattttt gaggcctact tggtttggaa atatggtttg
    28081 gacaagtccg ttctaaaagg gaccatggct caggttgtga cagatctgac tggttttcga
    28141 acgactagct ttgctggagg gggcttgatc ggggtcgctc tttatattcc aacagccttt
    28201 ctcttttcaa atatcggaac ttactttatt ggttctatct tgattttagt gggttctctc
    28261 ctagtcagcc cttggtctgt ttacgatatt gctgaatttt tcagtagagg ctttgccaaa
    28321 tggtgggaag ggcacgagcg tcgaaaagag gaacgctttg tcaaacaaga agaaaaagct
    28381 cgccaaaagg ctgagaaaga ggctagatta gaacaagaag agactgaaaa agccttactc
    28441 gatttgcctc ctgttgatat ggaaacgggt gaaattctga cagaggaagc tgttcaaaat
    28501 cttccaccta ttccagaaga aaagtgggtg gaaccagaaa tcatcctgcc tcaagctgaa
    28561 cttaaattcc ctgaacagga agatgactca gatgacgaag atgttcaggt cgatttttca
    28621 gccaaagaag cccttgaata caaacttcca agcttacaac tctttgcacc agataaacca
    28681 aaagatcagt ctaaagagaa gaaaattgtc agagaaaata tcaaaatctt agaagcaacc
    28741 tttgctagct ttggtattaa ggtaacagtt gaacgggccg aaattgggcc atcagtgacc
    28801 aagtatgaag tcaagccggc tgttggtgta agggtcaacc gcatttccaa tctatcagat
    28861 gacctcgctc tagccttggc tgccaaagat gtccggattg aagcaccaat ccctgggaaa
    28921 tccctaatcg gaattgaagt gcccaactcc gatattgcca ctgtatcttt ccgagaacta
    28981 tgggaacaat cgcaaacgaa agcagaaaat ttcttggaaa ttcctttagg gaaggctgtt
    29041 aatggaaccg caagagcttt tgacctttct aaaatgcccc acttgctagt tgcaggttca
    29101 acgggttcag ggaagtcagt agcagttaac ggcattattg ctagcattct catgaaggcg
    29161 agaccagatc aagttaaatt tatgatggtc gatcccaaga tggttgagtt atctgtttac
    29221 aatgatattc cccacctctt gattccagtc gtgaccaatc cacgcaaagc cagcaaggct
    29281 ctgcaaaagg ttgtggatga aatggaaaac cgttatgaac tctttgccaa ggtgggagtt
    29341 cggaatattg caggttttaa tgccaaggta gaagagttca attcccagtc tgagtacaag
    29401 caaattccgc taccattcat tgtcgtgatt gtggatgagt tggctgacct catgatggtg
    29461 gccagcaagg aagtggaaga tgctatcatc cgtcttgggc agaaggcgcg tgctgcaggt
    29521 atccacatga ttcttgcaac tcagcgtcca tctgttgatg tcatctctgg tttgattaag
    29581 gccaatgttc catctcgtgt agcatttgcg gtttcatcag gaacagactc ccgtacgatt
    29641 ttggatgaaa atggagcaga aaaacttctt ggtcgaggag acatgctctt taaaccgatt
    29701 gatgaaaatc atccagttcg tctccaaggc tcctttatct cggatgacga tgttgagcgc
    29761 attgtgaact tcatcaagac tcaggcagat gcagactacg atgagagttt tgatccaggt
    29821 gaggtttctg aaaatgaagg agaattttcg gatggagatg ctggtggtga tccgcttttt
    29881 gaagaagcta agtctttggt tatcgaaaca cagaaagcca gtgcgtctat gattcagcgt
    29941 cgtttatcag ttggatttaa ccgtgcgacc cgtctcatgg aagaactgga gatagcaggt
    30001 gtcatcggtc cagctgaagg taccaaacct cgaaaagtgt tacaacaata aaaaaatagc
    30061 ttctttccaa gtttggaggg aagctatttt agtggctatt gattgctttt attttctgaa
    30121 gttggcgcat tggactgttt ttcgttttca gtagcaggtt tacttgaagc aggagtagaa
    30181 gagtcctgag ttgctgtttt ctgatcttct tttttctctt ccttgacgct agattttggt
    30241 gtttcctctt gctgtgtttt ttcttgacta gtgttagtct ctttagttgg actggtgttt
    30301 tccttagggg attccttttg gatttctttg acaatggttg tcgtctggct tgtcgtaggt
    30361 tcttttttaa tatttttgtt attatccaag gcgttcataa tcgtgatact tgcggtaatc
    30421 aagccaagga tactagcgat tgtagcaacg gttttttgaa agactgtaaa gccttttttg
    30481 atgtgttctg tttttggttt tgaagttcta cgatagttag acatacattc tctcctttga
    30541 ttatgattta ttatactctg tttctttaaa aaaatcttaa aaaaagagaa atttcccttt
    30601 cttgtcgcaa gctccgtttc atgatacaat agaggaagtg attttagaaa gcgtgagaaa
    30661 catgatttac tttgataatt cagcgacgac caagccttat cctgaagccc ttgaaaccta
    30721 tatgcaggtc gcttcaaaaa ttttaggaaa cccatctagt ctccatcgtt tgggagacca
    30781 agcaacacga atcttagatg cttctcgcca acagattgca gatttaatcg gtaagaaaag
    30841 cgatgaaatc ttctttacct cgggtggaac agaaggggat aactggctta tcaagggtgt
    30901 ggcctttgaa aaagctcagt ttggcaagca catcattgtt tcagccattg aacatccagc
    30961 agtcaaagag tcagccctct ggttgaaaag tcaaggattt gaagtggatt ttgctccagt
    31021 tgataagaaa ggcttggtcg atgttgaggc gttagcaggt ttgatacggc atgatacaat
    31081 cctcgtttcc atcatggctg tgaacaatga aatcggctct atccaaccta ttgaggctat
    31141 ttcagaattc ttggcagaca agccgactat ttccttccac gttgatgcgg ttcaggcgct
    31201 tgccaaaatt ccgactgaaa agtatctgac agaacgggtg gattgcgcga ctttctctag
    31261 tcacaagttc cacggggttc gaggtgttgg ctttgtctat atcaaatctg gcaagaagat
    31321 tacacctctt cttacaggtg gtggccagga gcgagattat cgttcgacaa ctgaaaatgt
    31381 ggcagggatt gcagcgacag ccaaggccct ccgtttgtct atggaaaagc tagatatctt
    31441 taggagcaag actgggcaga tgaaggcagt gattcgccaa gctcttctga actatccgga
    31501 tatttttgtc ttttcagatg aggaaaactt tgcacctcat attctgactt ttggaatcaa
    31561 aggtgttcga ggtgaagtca tcgttcacgc ctttgaagac tatgatattt tcatctcaac
    31621 aacctcagct tgttcatcta aggcaggaaa accagccggt accttgattg ccatgggagt
    31681 ggacaaagat aaggccaagt cagctgtgcg tcttagccta gacttggaaa atgatatgag
    31741 tcaggtcgag cagtttttga ccaagttaaa attgatttac aatcaaacta gaaaagtaag
    31801 ataggagcat tcatgcagta ttcagaaatt atgattcgct acggagagtt gtcaaccaag
    31861 ggtaaaaacc gtatgcgttt catcaataaa cttcgtaata atatttcgga cgttttgtct
    31921 atctataccc aagttaaggt aacagcagat cgcgaccgtg cccacgctta cctcaatgga
    31981 gctgattaca cagcagttgc agaatctctc aaacaagttt ttggaattca aaacttttct
    32041 cctgtttata aggttgaaaa atctgtagaa gttttgaagt cttctgtcca agagattatg
    32101 cgggacatct acaaggaagg tatgaccttt aagatttcta gcaagcgtag cgaccacaac
    32161 tttgaacttg atagtcgtga actcaaccaa acacttggag gggctgtatt cgaagccatt
    32221 ccaaatgtgc aagttcaaat gaaaagtcct gacatcaatc ttcaggtgga gattcgtgaa
    32281 gaagcagcct atctttctta tgaaaccatt cgtggggctg gtggtttgcc agttggaact
    32341 tcaggtaaag ggatgctcat gttgtcagga gggattgact cacctgtagc aggttatctt
    32401 gctcttaagc gtggggtgga tatcgaggca gttcactttg ctagtccacc atatactagt
    32461 cctggtgccc tcaagaaagc gcaggacttg acccgtaaat tgaccaagtt tggcggaaat
    32521 atccagttta tagaggtgcc tttcacagag attcaagagg aaatcaaagc caaagcgcca
    32581 gaagcttatt tgatgactct aactcgtcgc tttatgatgc ggattactga ccgtattcgt
    32641 gaggtacgaa atggtttggt tatcatcaat ggggaaagtc taggtcaagt agccagccaa
    32701 acccttgaaa gtatgaaggc tatcaatgct gttaccaaca ctcccatcat tcgtcctgtg
    32761 gttaccatgg acaagttgga aatcattgac atcgcccagg aaatcgatac ctttgacatt
    32821 tcaatccaac cgtttgaaga ctgttgtacc atttttgcac cagatcgtcc aaaaacaaat
    32881 cctaaaatta agaatgcgga gcagtacgaa gcgcgtatgg atgttgaagg cttggttgag
    32941 cgagcagtgg ctggaatcat gattactgaa atcacacctc aagccgaaaa agatgaagtt
    33001 gatgacttga ttgacaatct gctctaattc agaaaatcca aaagaatagc gaaaatcagt
    33061 aaaaaaagtt agttttttct ctaaaaacag gtaaaaaact aacttttttt atttttatga
    33121 tataatgata taaaattttg aatatagaga gttttctgac aatgaatcaa tcctactttt
    33181 atctaaaaat gaaagaacac aaactcaagg ttccttatac aggtaaggag cgccgtgtac
    33241 gtattcttct tcctaaagat tatgagaaag atacagaccg ttcctatcct gttgtatact
    33301 ttcatgacgg gcaaaatgtt tttaatagca aagagtcttt cattggacat tcatggaaga
    33361 ttatcccagc tatcaaacga aatccggata tcagtcgcat gattgtcgtt gctattgaca
    33421 atgatggtat ggggcggatg aatgagtatg cggcttggaa gttccaagaa tctcctatcc
    33481 cagggcagca gtttggtggt aagggtgtgg agtatgctga gtttgtcatg gaggtggtca
    33541 agccttttat cgatgagacc tatcgtacaa aagcagactg ccagcatacg gctatgattg
    33601 gttcctcact aggaggcaat attacccagt ttatcggttt ggaataccaa gaccaaattg
    33661 gttgcttggg cgttttttca tctgcaaact ggctccacca agaagccttt aaccgctatt
    33721 tcgagtgcca gaaactatcg cctgaccagc gcatcttcat ctatgtagga acagaagaag
    33781 cagatgatac agacaagacc ttgatggatg gcaatatcaa acaagcctat atcgactcgt
    33841 cgctttgcta ttaccatgat ttgatagcag ggggagtaca tctggataat cttgtgctaa
    33901 aagttcagtc tggtgccatc catagtgaaa tcccttggtc agaaaatcta ccagattgtc
    33961 tgagattttt tgcagaaaaa tggtaagtta agaaaggaaa aaacgaaatg catattgaac
    34021 atcttagcca ctggagtggt catcttaacc gtgaaatgta ccttaaccgt tatggacatg
    34081 gtgggattcc agttgtggtc tttgcttcat caggtggtag tcacaacgaa tactatgatt
    34141 ttggcatgat tgatgcctgt gcttccttta tcgaggaagg ccttgtccag ttctttaccc
    34201 tatctagttt ggatagtgag agctggttgg ctacttggaa aaatgctcat gaccaagcgg
    34261 aaatgcaccg tgcctacgaa cgttatgtga ttgaggaggc cattctttta tcaagcacaa
    34321 gacaggttgg tttgatggca tgatgacgac aggttgctct atgggagcct atcatgcact
    34381 caatttcttc ctccagcatc cagatgtctt taccaaagtg attgctctca gtggtgttta
    34441 cgacgcacgt ttctttgtcg gtgattacta caacgatgat gctatttacc aaaactcgcc
    34501 agtagattat atttggaacc aaaacgacgg ctggtttatt gaccgttacc gtcaggcaga
    34561 gattgtgctg tgtacggggc ttggagcctg ggaacaagat ggtttgccat ccttttacaa
    34621 gctcaaagaa gcctttgaca agaaacaaat tccagcctgg tttgctgaat ggggacatga
    34681 tgtcgcccat gactgggaat ggtggcgtaa acaaatgcct tatttcctcg gtaatctcta
    34741 tttataaaag gagttaccta tgaattacct tgttatttct ccctactatc cacaaaactt
    34801 tcaacagttt accatcgaac tagctaataa aggcatcaca gtcttgggaa ttggtcaaga
    34861 gtcttacgag caattggatg agcccttgcg caatagcttg accgagtatt ttcgtgttga
    34921 taatcttgag aacatagatg aagtcaaacg tgcagttgct tttctctttt ataaacatgg
    34981 tccaattggc cgcatcgagt ctcacaatga atactggctt gagctagacg caacactcag
    35041 agaacaattc aatgtttttg gtgccaaacc agaggatctc aaaaagacga aatataagtc
    35101 tgaaatgaag aaacttttca aaaaagcagg tgttcctgtg gtacctggag ctgttatcaa
    35161 gacggaagca gatgttgatc aagcagtgaa agaaatcggt cttccaatga ttgccaaacc
    35221 tgataatgga gtgggagcag ccgcaacctt taaacttgag acagaagacg atatcaatca
    35281 cttcaagcaa gaatgggacc attcaaccct ttatttcttt gaaaaatttg tcacttccag
    35341 cgaaatctgt acctttgacg ggctcgtgga caaggatgga aagattgtct tctcaacaac
    35401 ctttgactac gcctatacac cgcttgacct catgatttat aagatggaca attcttatta
    35461 tgtgctcaag gatatggatc ctaaactgcg caagtatggg gaagcaattg tcaaagaatt
    35521 tggtatgaaa gaacggtttt tccatattga gttcttccgt gagggggacg attatattac
    35581 catcgagtac aataaccgcc ctgcaggtgg ttttaccatt gatgtttata actttgctca
    35641 ttccttggac ctttatcgtg gctatgcagc tattgtcgca ggagaggagt tcccggcgtc
    35701 agactttgaa actcagtatt gtttggctac ttctcgccgt gcaaatgctc actatgttta
    35761 ttcagaagag gatttgcttg ccaaatatag ccagcagttc aaggttaaaa aagtcatgcc
    35821 agctgccttc gcggaacttc aaggagatta cctgtatatg ctgaccactc cgagtcgaca
    35881 agaaatggag cagatgattg cagatttcgg acaacgtcaa gaataagaac tatcggatta
    35941 aggaaattaa ctcccttaat ccttttgttt tgtctgataa aaaataagag catcccaaca
    36001 aggtagctat cataaaactt gttcgataac tatttgaagc aggattaggt ggtcagaaat
    36061 taaattttaa tatttcaatt gagtcatagt attgtgtttg cgtatcctta aatcagctaa
    36121 aaggatccat gacgacacct atacgatata gttttcaaga taccaaacaa gtctattaat
    36181 attcaatgaa aatcaaagag caaactagga agctagccgc aggtttctca aaacactgtt
    36241 ttgaggttgt ggatagaact gacagagtca gtatcatata cctacggcaa ggtgaagctg
    36301 acgtggtttg aagagatttt cgaagagtat aaaatattca ggtgacgcat agatatagtt
    36361 aattgaagct ttgtttgaaa tctgataaaa taatgatatt actaagtttt aaaaactaaa
    36421 gaaaagggaa gatatgatta caggcgaatt aaaaaataaa atcgatcagc tgtgggaaat
    36481 tctttggaca gaaggaaacg caaatccttt aacaaatatt gaacagttga cttatctctt
    36541 atttatgaaa gatttggata gtgtcgagct tggacgtgaa agtgatgctg aatttctagg
    36601 gattccttat gagggagttt ttccaaaaga taaacctgaa taccgttggt caacttttaa
    36661 aaatatagga gatgctcagg aagtttatcg tttaatgact caggagattt ttccgtttat
    36721 taaaaatctc aagggggata cagatgatac agccttttca cgatatatgc gagaagctat
    36781 ttttcaaata aataaacctg ctacgcttca aaaggcaatt tctatcttag atgtttttcc
    36841 aactagggga ttagatgtag attttgataa tgacaaacaa agtattactg atatcggaga
    36901 tatctatgaa tatctgttat caaaattgtc gaccgcaggt aaaaatggac agttccgtac
    36961 acctcgtcac atcatcgata tgatggttga gttgatgcaa ccgactatca aagatatcat
    37021 ctcagatccc gctatgggtt ctgctggctt cttagtatct gctagccgtt acttaaagcg
    37081 taagaaagat gaatgggaaa ccaatacaga taatatcaat cattttcata atcagatgtt
    37141 tcatggaaat gatacggata cgactatgtt gagacttggg gcgatgaaca tgatgctaca
    37201 tggagtagaa aatccacaaa tcagttacct tgactcgctg tctcaagata atgaagaagc
    37261 cgataaatat actttggttt tagcaaatcc tccttttaag ggctcacttg actacaattc
    37321 aacctctaat gaccttcttg caaccgtaaa aaccaaaaaa acagaattac tctttctttc
    37381 tcttttcttg cgaactttaa aaccaggtgg acgagcagca gttatcgtac ctgatggtgt
    37441 cctttttggt tcgtctaaag ctcataaagg aattcgtcag gaaattgtag agaatcataa
    37501 gcttgatgct gtaatctcaa tgcctagtgg tgtgttcaag ccttatgctg gagtttcaac
    37561 tgccattctc atctttacaa aaactggtaa tggtggtact gacaaagtct ggttttacga
    37621 tatgaaagcg gatggtttaa gtttggatga taagcgacaa ccgattagcg acaatgatat
    37681 tccagatatt atcgaacgct ttcatcatct tgaaaaagaa gcagaacgtc agagaacgga
    37741 tcaatctttc tttgttccag ttgctgagat aaaggaaaat gattatgatt tgtctatcaa
    37801 taaatataaa gagattgagt atgaaaaagt tgagtatgaa ccaacagagg tcatcttaaa
    37861 gaaaatcaat gatttagaaa aagaaattca agctggcttg gctgaattag aaaaattact
    37921 caagtagaga ggtggctgta tgaaaaaagt gaagttgggg gaagtcttat ctctaaaaaa
    37981 aggcaagaaa gccactgtac ttgctgaaca aacaactcta agccaacgtt atattcaaat
    38041 agatgattta agaaataata ataatttaaa attcactgaa agtttaaata tgactgaagc
    38101 actcccagat gatattctga tagcatggga tggagctaat gcaggaacag ttggttatgg
    38161 attatcggga gctgttggta gtacaattac ggtcttaaaa aagaatgagc gatacaaaga
    38221 aaaaattata tcagattact tgggagtctt tttggaaagt aaatcgcagt atttacgaga
    38281 acattcaaca ggtgcaacaa ttcctcattt aaacaagaat atattacttg atttacaatt
    38341 agaattgcta ggtatcgaag aacaagagaa cattatctgt attcttaata cgattaaaag
    38401 gcttattact aaaagaaaat tgcagttaga tgaactaaac ttgctcgtca aatcccgatt
    38461 taacgagatg tttggggatg ttattctaaa tgaaaaagaa tggaaagtta gcaaatggaa
    38521 cgagattcta acaataagaa atggtaaaaa tcaaaaacag gttgaagatg ctgatgggaa
    38581 atttcctatt tatggaagtg ggggaattat gggatatgct aaagattgga tagtgaagaa
    38641 aaattcagtt attattggac gtaaaggaaa tataaataaa cctattttag ttagagaaaa
    38701 tttttggaat gtagatacag catttggatt agagcctgtt ttagaaaaaa taaactcaga
    38761 atatttattc tatttttgtc aattatacaa ttttgagaag ttaaataagg ctgtaacaat
    38821 acctagttta actaaatcag atttattaaa tatttccatc cccctccccc cactagccct
    38881 ccaaaatgag ttcgcagact ttgtagccct ggtcgacaaa tcacaatttg cttgtgagat
    38941 agctataaaa gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt
    39001 taaagtgaga aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct
    39061 ttttcaaaac cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc
    39121 tttatggcgc gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat
    39181 ttagaagctc cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat
    39241 atcgtagatt ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct
    39301 gctcatggtg gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag
    39361 tttgttaatt ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag
    39421 aagtgcttac cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag
    39481 ttacaagaca gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta
    39541 gaagttcaag agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct
    39601 ttccatattg atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc
    39661 cgtttagcag gatggatatt tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc
    39721 aagcacggtt caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt
    39781 ttagcgattg tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc
    39841 aaagaatatg ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca
    39901 aatgggttga agcactatat acttgatggt ccgaaccgcc gccagattgc aggcttttac
    39961 tctcaagaag aattgcaatt agtgatggat agacgtcatc ttcaaaaacc gcttgaggat
    40021 atttctagta aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca
    40081 agcgtttgtg aagctttctc tgatcatcgt agacaggcac ttttggttat ggcaactggg
    40141 gcggggaaaa ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta
    40201 aaaaacgttc tcttcttagc cgatagaact tccttggtta agcaagcata tgattcgttt
    40261 agaaaattac tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa
    40321 tcaagtcgaa tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa
    40381 gaagtaaatc aacgcccttt tactgttggg cattttgacc ttatcataat tgacgaatct
    40441 caccgttcta tttatcagaa atacaagtcc atttttgatt attttgatgc aaggattgta
    40501 ggcttaacag ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg
    40561 gagaatgggg ttccaacata tgcatatgat ttggaagagg ctgttaaaga cggatattta
    40621 gtagcctatc attctatcga aaccaaactg aaactaccta cggatggtct acattatgat
    40681 gatttgtccg aagaagaaaa ggaacatttt gatagcaaat ttgaagacga tagctgtgaa
    40741 aaagatattg atgggagtgt gtttaattcc tttattttca ataaaagtac agtagaaatt
    40801 gttttaaatg aactcatgac aagaggaatt cagacagcct cgggtgatga aattggtaaa
    40861 actattattt ttgctaaaaa tcatgaccat gcggaatata tcagaggtat ttttaacaac
    40921 cgctatcctg aaaaagggag cgactatgct caggtgattg attatagtat taagcattat
    40981 cagaccttga ttgatgattt taaaattaag gagaagtatc ctcaaattgc gatttctgtc
    41041 gatatgttag atacaggtat tgatgtacca gaggttgtta atttagtctt cttcaagaaa
    41101 gtacgctcta aaactaagtt ttggcagatg attggtcgag gaacccgtct atgtaaagat
    41161 ttatttggac ctgagcagga taaggaaaac ttcttggtat ttgattatgg ggacaatttt
    41221 gattattttc gtgcagatcc aagagatgga gagggtcgtc acattgtttc gctgactcag
    41281 cgtttattta atatcaaagt ggacttgatt cgagaacttc agggactcca ataccaagaa
    41341 gatcagtttg cgagagcata ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag
    41401 agcttaaatg agttggactt cagggttcgt atggttttag atacagttta tagctatagg
    41461 aaattggaaa gttggcagaa tctaactgct gttacaagtg aaaccattca aaaaaatctc
    41521 tctccgcttt tatttgatga agataaagaa gatgagatgg cgaggagatt tgatttgtgg
    41581 ttgcttcata ttcagttggg gcaactgaca gctaaatctt ccactgttca tatttcccaa
    41641 gtgatgaaga cggctagagc tctttctgct attggcaata tcccgcaggt ttttgagcag
    41701 gctgaaatta tggctctttg tcaactgtag tgggttgaaa aaaagctaag cttgagaaag
    41761 gacaaatttt gtcctttctt ttttgatatt cagggcgata aaaatccgtt ttttgaagtt
    41821 ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat tattggtcgc
    41881 ttccagtttg gcattagaat agtgtagttg aagggcgttg acgattttct ctttgttctt
    41941 tagaaaggtt ttaaagacag tctgaaaaag aggatgaacc tgcttcagat tgtcctcaat
    42001 gagtccgaaa aatttctcag ggtctttgtt ctgaaagtga aaaagtaaga gttgatagat
    42061 ctgatagtgg tgtttcaagt cttctgaata gcttaaaatc ttgtcaagaa tttctttatt
    42121 tgttaagtgc atgcgaaaag tagggcgata aaaacgttta tcgctcaatt tacgactatc
    42181 ctgttggatg agtttccagt aacgcttgat agccttgtat tcatgagatt ttcgttcaaa
    42241 ctgattcata atttgaacac gaaaacgact catggcacgg ctgagatgtt ggataatatg
    42301 gaaacgatct agaacgattt tagcacacgg aaaaagctgt ttagccaagt catagtaagg
    42361 actaaacata tccatcgtaa tgattttcac ttgacaacga acggctctat cgtagcgaag
    42421 aaagtgattt cggatgacag cttgtgttct gccttcaaga acagtgataa tattaagatt
    42481 atcaaaatct tgcgcaatga aactcatctt tcccttagtg aaggcatact catcccaaga
    42541 cataatcttt ggaagccgag aaaaatcatg ctcaaagtga aagtcattga gcttgcgaat
    42601 gacagttgaa gttgaaatgg ccagctgatg
//
LOCUS       DAVBED010000012        39690 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBED010000012 DAVBED010000000
VERSION     DAVBED010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.012"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..151
                     /locus_tag="VQ547_000648"
     CDS             <1..151
                     /locus_tag="VQ547_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HET2542539.1"
                     /translation="WYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNA
                     NGEWV"
     gene            552..1673
                     /gene="mnmA"
                     /locus_tag="VQ547_000649"
     CDS             552..1673
                     /gene="mnmA"
                     /locus_tag="VQ547_000649"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2542540.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1814..2269
                     /locus_tag="VQ547_000650"
     CDS             1814..2269
                     /locus_tag="VQ547_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2542541.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2279..4192
                     /gene="mnmG"
                     /locus_tag="VQ547_000651"
     CDS             2279..4192
                     /gene="mnmG"
                     /locus_tag="VQ547_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2542542.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4616..6295)
                     /locus_tag="VQ547_000652"
     CDS             complement(4616..6295)
                     /locus_tag="VQ547_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2542543.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6297..6530)
                     /locus_tag="VQ547_000653"
     CDS             complement(6297..6530)
                     /locus_tag="VQ547_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2542544.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6912..7133
                     /locus_tag="VQ547_000654"
     CDS             6912..7133
                     /locus_tag="VQ547_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542545.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7346..7498)
                     /gene="cibB"
                     /locus_tag="VQ547_000655"
     CDS             complement(7346..7498)
                     /gene="cibB"
                     /locus_tag="VQ547_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2542546.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7500..7685)
                     /gene="cibA"
                     /locus_tag="VQ547_000656"
     CDS             complement(7500..7685)
                     /gene="cibA"
                     /locus_tag="VQ547_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2542547.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7863..8546
                     /gene="tsaB"
                     /locus_tag="VQ547_000657"
     CDS             7863..8546
                     /gene="tsaB"
                     /locus_tag="VQ547_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2542548.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8543..8980
                     /gene="rimI"
                     /locus_tag="VQ547_000658"
     CDS             8543..8980
                     /gene="rimI"
                     /locus_tag="VQ547_000658"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2542549.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8970..9980
                     /gene="tsaD"
                     /locus_tag="VQ547_000659"
     CDS             8970..9980
                     /gene="tsaD"
                     /locus_tag="VQ547_000659"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2542550.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10026..11326)
                     /locus_tag="VQ547_000660"
                     /pseudo
     CDS             complement(10026..11326)
                     /locus_tag="VQ547_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11602..11953)
                     /locus_tag="VQ547_000661"
                     /pseudo
     CDS             complement(11602..11953)
                     /locus_tag="VQ547_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12060..12352)
                     /locus_tag="VQ547_000662"
                     /pseudo
     CDS             complement(12060..12352)
                     /locus_tag="VQ547_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12595..13801
                     /locus_tag="VQ547_000663"
                     /pseudo
     CDS             12595..13801
                     /locus_tag="VQ547_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13794..14442
                     /locus_tag="VQ547_000664"
                     /pseudo
     CDS             13794..14442
                     /locus_tag="VQ547_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14452..16068
                     /locus_tag="VQ547_000665"
     CDS             14452..16068
                     /locus_tag="VQ547_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542551.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16088..16932
                     /locus_tag="VQ547_000666"
                     /pseudo
     CDS             16088..16932
                     /locus_tag="VQ547_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17000..18501
                     /locus_tag="VQ547_000667"
                     /pseudo
     CDS             17000..18501
                     /locus_tag="VQ547_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18513..19262
                     /locus_tag="VQ547_000668"
     CDS             18513..19262
                     /locus_tag="VQ547_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2542552.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19275..20447
                     /locus_tag="VQ547_000669"
     CDS             19275..20447
                     /locus_tag="VQ547_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2542553.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20842..21705
                     /locus_tag="VQ547_000670"
     CDS             20842..21705
                     /locus_tag="VQ547_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2542554.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21991..22224
                     /locus_tag="VQ547_000671"
     CDS             21991..22224
                     /locus_tag="VQ547_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542555.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22246..22923
                     /locus_tag="VQ547_000672"
     CDS             22246..22923
                     /locus_tag="VQ547_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2542556.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22935..23600
                     /locus_tag="VQ547_000673"
     CDS             22935..23600
                     /locus_tag="VQ547_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2542557.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23672..24898
                     /locus_tag="VQ547_000674"
     CDS             23672..24898
                     /locus_tag="VQ547_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2542558.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25249..25326)
                     /locus_tag="VQ547_000675"
                     /pseudo
     CDS             complement(25249..25326)
                     /locus_tag="VQ547_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25397..26053
                     /locus_tag="VQ547_000676"
     CDS             25397..26053
                     /locus_tag="VQ547_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2542559.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            26043..26366
                     /locus_tag="VQ547_000677"
     CDS             26043..26366
                     /locus_tag="VQ547_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2542560.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26470..27300
                     /locus_tag="VQ547_000678"
     CDS             26470..27300
                     /locus_tag="VQ547_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542561.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27341..27418
                     /locus_tag="VQ547_000679"
                     /pseudo
     CDS             27341..27418
                     /locus_tag="VQ547_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27522..28352
                     /locus_tag="VQ547_000680"
     CDS             27522..28352
                     /locus_tag="VQ547_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542562.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28506..29360
                     /locus_tag="VQ547_000681"
     CDS             28506..29360
                     /locus_tag="VQ547_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2542563.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29460..30833
                     /locus_tag="VQ547_000682"
     CDS             29460..30833
                     /locus_tag="VQ547_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2542564.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30826..31887
                     /locus_tag="VQ547_000683"
     CDS             30826..31887
                     /locus_tag="VQ547_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2542565.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31889..32581
                     /locus_tag="VQ547_000684"
     CDS             31889..32581
                     /locus_tag="VQ547_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542566.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32611..33180)
                     /locus_tag="VQ547_000685"
     CDS             complement(32611..33180)
                     /locus_tag="VQ547_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2542567.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33315..33929
                     /locus_tag="VQ547_000686"
     CDS             33315..33929
                     /locus_tag="VQ547_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2542568.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33931..35577
                     /locus_tag="VQ547_000687"
     CDS             33931..35577
                     /locus_tag="VQ547_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2542569.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35589..36875
                     /locus_tag="VQ547_000688"
     CDS             35589..36875
                     /locus_tag="VQ547_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542570.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36936..37469
                     /locus_tag="VQ547_000689"
     CDS             36936..37469
                     /locus_tag="VQ547_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542571.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37547..38017
                     /gene="nrdI"
                     /locus_tag="VQ547_000690"
     CDS             37547..38017
                     /gene="nrdI"
                     /locus_tag="VQ547_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2542572.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38310..39572)
                     /locus_tag="VQ547_000691"
     CDS             complement(38310..39572)
                     /locus_tag="VQ547_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2542573.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12053 a         6875 c         8561 g        12201 t
ORIGIN      
        1 ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcaga
       61 taaatggtac tatgtcaatg gtttaggtgc ccttgcagtc aacacaactg tagatggcta
      121 taaagtcaat gccaatggtg aatgggttta agccgattaa attaaatcat gttaagaaca
      181 tttgacattt taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt
      241 ctttaggtac ctatcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct
      301 aacttgaaaa atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa
      361 gataagaaga aggtatactc acatcattca cataatctgt atgttgacta taagtttaaa
      421 aaaacaattt ttaagctctt ccttgtcttc tccaaccaag cgtgttataa tgaatactgc
      481 tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa cgaatagatg
      541 ggagacttac catgagtgat aactctaaaa cacgtgttgt cgtggggatg agtggtggtg
      601 ttgattcgtc ggtgacggct cttttgctca aggagcaggg ctacgatgtg atcggtatct
      661 tcatgaagaa ctgggatgac acagatgaaa acggcgtctg tacggcgacc gaagattaca
      721 aggatgtggt tgcggtggca gaccagattg gcattcccta ctactctgtc aattttgaaa
      781 aagagtactg ggaccgcgtt tttgagtatt tcctagcgga ataccgtgca gggcgcacgc
      841 caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg gactatgcca
      901 tgaccttggg ggcagactat gtagcgactg ggcattatgc tcgagtggcg cgtgatgagg
      961 acggcactgt tcacatgctt cgtggcgtgg acaatggcaa ggaccagacc tatttcctca
     1021 gccaactttc gcaagaacaa ctccaaaaaa ccatgttccc tctgggacat ttggaaaagc
     1081 ctgaagtacg cagactagca gaagaagcag gcctttcgac tgctaagaag aaagactcga
     1141 cagggatttg ctttatcgga gaaaagaact ttaaaaactt tctcagcaac tacctgccag
     1201 ctcagcctgg tcgcatgatg actgtggatg gtcgcgatat gggcgagcat gcaggtctta
     1261 tgtactatac aatcggtcag cgtggcggac tcggtatcgg tgggcaacac ggcggtgaca
     1321 atgccccttg gttcgttgtc ggaaaagatc taagcaagaa tattctctat gtaggacaag
     1381 gattctacca tgattcgctc atgtcaacta gcctagaagc cagtcaagtc cactttactc
     1441 gtgaaatgcc agaagagttt acgctagaat gtacggctaa attccgttac cgtcagcctg
     1501 actctaaggt gaccgtccat gtcaaaggag acaaggcaga agttatcttt gcggaaccac
     1561 aacgcgcgat tacaccagga caggcagttg tcttttacga tggcgaagag tgtctaggtg
     1621 gcggtttgat tgacaatgct taccgcgatg gacaagtttg tcagtacatt tagattgaca
     1681 aattttctca atttgctaca ataataacag caatagaaat gatggtcaaa gctcatggat
     1741 gttgcaggct tttttgtcct gcacttcttt gtagttttga ctgtttttgt gtcgtttaag
     1801 ggaaaggaca agaatgactc aacaagactt tcggacaaaa gtagacaata cggtttttgg
     1861 tgttcgggct acagccttga ttgtccaaaa tcacaagctt ctagttacca aagacaaggg
     1921 caagtattac actattggag gtgcgattca agtcaatgaa agcacggaag acgcggtagt
     1981 ccgtgaagtg aaggaagaac tggatgtcaa agctcaagct gggcagctag cttttgtggt
     2041 tgaaaatcgt tttgaagtgg acggcgtttc ctatcacaat atcgagtttc attatctggt
     2101 ggatttgctt gaagatgccc cgttgaccat gcaggaagat gagaaaaggc agccctgtga
     2161 gtggattgac ttggataagc tccagaatat ccagctagtt ccagcctttt taaaaacagc
     2221 cctaccagat tgggaaggcc aactaagaca cattcatctt gaggaatagg agagaaacat
     2281 gacttatcat tttactgaag aatacgatat tattgtaatt ggtgcgggac acgctggggt
     2341 tgaggcttcc ttggccgcta gccgtatggg ctgtaaggtc ctgcttgcga ccatcaatat
     2401 tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt ggttctgcta aggggattgt
     2461 cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag accattgaca agacttacat
     2521 ccagatgaag atgctcaaca cagggaaggg accagccgtt cgtgcccttc gtgcgcaggc
     2581 tgataaggaa ctttactcta aggaaatgcg caagacagtt gaaaatcaag aaaatctgac
     2641 ccttcgtcaa accatgattg atgagatttt ggtggaagat ggcaaggttg tcggtgtgcg
     2701 tacagccacc catcaagaat atgctgctaa ggctgttatt gtgacgacag ggactgctct
     2761 ccgtggggaa attatcatcg gagacctcaa gtactcatca ggtcctaacc acagcttggc
     2821 ttctattaac ctagctgaca atctcaagga actgggtctc gaaatcggtc gtttcaagac
     2881 aggaacccct ccacgtgtca aggcttcttc tatcaattac gatgtgacgg aaattcagcc
     2941 aggagacgaa gtgcctaatc atttctcata cacttcacgt gatgaggatt atgtcaaaga
     3001 tcaagtgcca tgctggttga cctataccaa tggtaccagt catgagatta tccaaaacaa
     3061 cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc gttactgtcc
     3121 gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa cgtcaccaac tcttccttga
     3181 gccagaaggg cgcaatactg aggaagtcta tgttcaagga ctttcaacca gtctgcctga
     3241 ggatgtccag cgtgacttgg ttcattccat caaaggtttg gaaaatgcag agatgatgcg
     3301 gacaggttat gctattgagt atgatatggt cttgcctcat cagttgcgtg cgactttgga
     3361 aaccaagaaa atctcaggtc tcttcactgc tggtcagaca aatggaacat caggttatga
     3421 agaagctgct ggccaaggga ttatcgcggg tatcaatgcg gctctgaaaa tccaaggtaa
     3481 acctgagttg attctaaaac gaagtgacgg ttatatcggg gtgatgatcg acgacttggt
     3541 gaccaaggga accattgaac cttaccgtct cttgaccagt cgtgctgaat accgtctcat
     3601 tcttcgtcat gacaatgctg atatgcgctt gactgagatg ggacgcgaga ttggccttgt
     3661 ggatgatgaa cgctgggctc gttttgaaat caagaaaaat caatttgata atgagatgaa
     3721 acgcctagac agtatcaaac tcaagccagt caaggaaacc aatgctaagg ttgaggaaat
     3781 gggcttcaag ccgttgacag atgcggtgac agccaaggaa ttccttcgcc gtccagaagt
     3841 ttcttaccaa gatgtggtgg ccttcatcgg accagctgca gaagacttgg atgacaagat
     3901 tatcgaattg attgaaacag aaatcaagta cgaaggctat atttccaaag ccatggatca
     3961 ggttgctaag atgaaacgta tggaagaaaa acgcattcca gccaatatcg actgggatga
     4021 catcgattct attgcgacgg aagctcgtca gaagttcaaa ctcatcaatc cagaaaccat
     4081 cggccaagcc agccgtattt cgggagtaaa cccagcagat atttctattt tgatggtgta
     4141 tctggaaggt aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat gatacgtcgt
     4201 cggcttctta cgaatgagtt caaagcttgg ctttgattca tctccaacct cccatagttc
     4261 cccgaactat gggagctaac tcaagttatg cattttccta gccttctggt ctgattttca
     4321 ttgagtttta atctcaaaag aaagcataga gaaaaacagc tccgaagacg gggctgtttt
     4381 gttgacttgt actcaatgaa aatcaaagag caaactagga agctagccgt aggttgctca
     4441 aagcactgct ttgaggttgt agatagaact gacgaagtca gctcaaaaca cagttttgag
     4501 gttgtagata gaactgacga agtcagctca aaacacagtt ttgaggttgt ggatagaact
     4561 gacgaagtca gtaacatata tacggcaagg cgaagctgac gtggtttgaa gagtattatt
     4621 cttcatctgg tgtgaggatc atcgggatga tgatcggttc acgttcggta ttttcataga
     4681 ggaaggggcg aatagcgttg acaatggcac cattgacaga ttgcacgcta gcatccttat
     4741 ttttcagtgc gatacgaatg gcattgaaga ggatacgctg gctttggcga atcaagtctc
     4801 cagactctct catgtagaca aagcctcggc tgaggatatc tgggccagac agaatcatct
     4861 gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc gtcttcagat agatcgcgac
     4921 gatctttgag gacagctgcg ccaatttcac cgatacgatt tccatcgaca tagatatctt
     4981 gggcgttgaa atgacctgcg atacgagctg agtcagcagt aagggcaagc acatcgccat
     5041 tgctcatgat aaagatattg tctttctcaa caccagtatc cactgctagt ccagcgtgga
     5101 ctttttgcat gcggtattca ccgtggacag gcatgaagta ttttggctta atcaagcgga
     5161 gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt atggatattg ttcactttac
     5221 cgtggataac ttcgacacca gcttcagaaa tgatgttaat cagcttgttg acgctagtag
     5281 tgtttccagg gatgggacta gaagagaaga taacggtatc acctggttgt aattgtactt
     5341 gacggtgggt tccgttggcg atacgagaga gggctgccat aggctcaccc tgactacctg
     5401 tacagaggat aagaacttct cctgcaggat aatctttgat ttcatttggc tcgataaagg
     5461 ttcccttagg agctttgatg tagccaagat cgattccgtt gacaatggcc ttttccatag
     5521 aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc agcttctgtt gcctgctgga
     5581 gacggaagat atttgaggca aaggatgcaa agatgatacg tccttcaata ccttggataa
     5641 tcttcataat ggactgacca acgacttttt cagagttggt aaaggttggt acttccgcat
     5701 ttgtcgagtc agacaggaga cagagcacgc cttcttcacc aagcgcagcc atacgatgca
     5761 agtccgcagg ttctccaact ggagtaaagt cgaacttaaa gtcacccgta cagacgattt
     5821 tcccttgagg agtatgaatg acaatcccca aaggctctgg aatagagtga gtcgttctaa
     5881 agaaagttgc cttgagattt ttaaaggtca actcggtgtt gtggttgatt tcgtaaagtt
     5941 tggcgttgcg caagaggccg tgttcttcga gtttcccacg gatcaaagcc aaggcaagcg
     6001 gtccagcgta gatagggaca tttgcttgct tgagtaggaa cggaatccca ccaatgtggt
     6061 cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc gatattgtct acgatgtaag
     6121 agtagtcagg aatgacatag tcgataccaa gcaagtcatc ttctgggaat ttaatcccag
     6181 catcgacgat gataatctcg tcttggtatt caattccgta agtgtttttc ccgatttctc
     6241 ctagaccacc gatggcaaaa acaccgactt cttcaggttt aagagtgtag gccatattag
     6301 aactccgtaa tttcgaaggc gccagtttct ttttcgtaat cgagcaattt gtcagacaag
     6361 agttcgatat attcgatatt gtactctggg cgattttctt cgacaagttg gcgagcagtg
     6421 atacggccct caagttctga gctggcatcg atgtctaggt aaagcgcgcg tgttgtttca
     6481 cggcgtgggc tacgttcttt tgtttcttga taaaaaactt tgtaaatcat atagttcctt
     6541 tctatttaca ggtcagctta ttccaaactt ttagcagata tttgcttgat ttcattccat
     6601 tttgtgtcta gattgacctt gattcgttac aattatttca attataccac aaaatgaaaa
     6661 attagtaaaa gacggaaacg agaaagttag gggacgattt cttcggtaag cgtttgcaaa
     6721 aacaaagaaa atgtgttatg ttgataacgg aagtgaagtt tattacttgt cataattcca
     6781 tatagatttt aagtcaagga ggttgcccta tgtataactt atttgctttt gctatcggag
     6841 ttcgtttgct agcttttatc gtttttgttt tgcgtttatg gaggaaatct tctatttgcc
     6901 aaactggaac gatgacaaac caagttcttg aggaaaatta cctttgtgac tctctactcg
     6961 ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttgg attaaatgct
     7021 tagatgccct gcttatgctg gggttttttg tttggggatg tagagatagt agatttacga
     7081 cacgaaaatt ccaccccatc tatcaagatg aggtggtctt tgcatttttc taaaatgata
     7141 tgacaatgga attttcaaag cttattattt ttatgggagt cattgttctg ctcaaaaata
     7201 gagttgaagc ataaaaataa aacaatacaa acagataaat cgaatggtaa agggatggta
     7261 gtaatgttca aatcattgag aatgctgagc aaactgtaag agatgaagac aataaaattt
     7321 atccttctaa aaatgtgttt cttatctagc atgacttacc aaacttttta cgaaggtctt
     7381 ttccaatggt ataacctgcc ataaataaag cgataccaac acctacacca aagccaccct
     7441 tgatttcttg caattcctta ttagaaattt cacgacagtt gttcaaatct ttcatcatat
     7501 taatctcctc ctaaaaaata accagctgcc aaaccagaac ctataagtgc tgttccacct
     7561 gcaatagctt tccaagatac tgctactcca aagataacca agggagcgag accgccatca
     7621 atatctgata attcattttc agataaggat aaaaattgat tgtcaagaat gtcaaaattt
     7681 gtcattgaac tttcctcctt ttttcttgtt cacttttata ttcggaaaag aaaaggaaaa
     7741 gtgagcattt ttttaaatta tttttagtta agtgagggca ctcttgtctg ggggcaaaga
     7801 aaattcccat gtgccatctt ttgtagtata atagtaagca gacaaaaaga taggaatgtg
     7861 ttatgaaagt attagctttt gatacgtcca gcaaggctct ttctctcgct attttagagg
     7921 ataagcaggt tcttgccgag acgacgatta atatcaagaa aaatcacagt attaccctca
     7981 tgccagccat tgattttttg atggagagtt tggactggac gcccaaggat ttggaccgaa
     8041 tcgtggtggc ggaagggcca ggtagctaca caggcttgcg aatcgcggta gccactgcca
     8101 agaccttgac tcatactctg aacattgagt tagttggtat gtctagcctc ttggctctgg
     8161 tgccatatca acaagaaggc ttgttcgttc ctttgatgga tgcgcgtcgc aacaatgttt
     8221 atgcaggatt ttatgaaaat gctaaacctg tcatgccaga agcgcaccta tcttttgaag
     8281 aggtgctaga aaaagtcaag ggtgctagtc aggtaacctt tgtcggagaa gttggcccct
     8341 ttgtggagca gattcaagaa cacttgccaa ggactaatta taaagaaacc ttgcctaatg
     8401 cagccaatct tgctctttta gcttgggaca aggaagcaga ctccttgcat gattttgtgc
     8461 caaattacct caaacgagtc gaggctgagg aaaactggct caagaaccat accgagtctg
     8521 gtgagtccta cattaaacgc ctatgataga aatcaagcga attcaacaac agcctgacct
     8581 agctcaagcc atctacgctg ttatggcagc tgtttaccta gtcagtcctt ggactctgga
     8641 gcaaatccaa gcagatctgt cccaagacca gacttggtat gcattggctt atgatggggc
     8701 agaagtgatt ggatttctag ctgtgcagga gaatcttttt gaagcagaag tcctgcaaat
     8761 cgctgtcaaa ggagcttatc agggtcaggg aattgcgtca gccttgtttg ctcaattgcc
     8821 gacagataag gagattttcc tcgaagtcag aaagtcaaat caacgagcgc aagcatttta
     8881 caagaaagaa aaaatggcgg tcatcgctga gcgaaaggcc tactaccatg acccagtcga
     8941 ggacgccatt atcatgaaga gagaaataga tgaaggatag atatatttta gcatttgaga
     9001 catcctgtga tgagaccagt gtcgccgtct tgaaaaacga cgatgagctc ttgtccaatg
     9061 tcattgctag tcaaattgag agtcacaaac gttttggtgg cgtagtgccc gaagtagcca
     9121 gtcgtcacca tgtcgaggtc attacagcct gtatcgagga ggcattggca gaagcaggga
     9181 ttaccgaaga ggacgtgaca gctgttgcgg ttacctacgg accaggcttg gtcggagcct
     9241 tgctagttgg tttgtcagct gccaaggcct ttgcttgggc tcacggactt ccactgattc
     9301 ctgttaatca catggctggg cacctcatgg cagctcagag tgtggagcct ttggagtttc
     9361 ccttgctagc cctcttggtc agcggcggac acacagagtt ggtttatgtt tcggaggcag
     9421 gagattataa gattgttggg gaaacccgtg atgatgcggt tggtgaggct tatgataagg
     9481 tcggccgtgt catgggcttg acctatcctg caggtcgtga gattgacgag ctggctcatc
     9541 aggggcagga tatttatgat ttcccccgtg ccatgattaa ggaagataat ctggagttct
     9601 ccttctcagg tttgaaatct gcctttatca atctttatca caatgccgag caaaagggag
     9661 aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc agcagttatg gacattctca
     9721 tggcaaaaac caagaaggct ttggagaaat atcctgttaa aaccctggtt gtggcaggtg
     9781 gtgtggcagc caataaaggt ctcagagaac gcctagcagc cgaaatcaca gatgtcaagg
     9841 ttatcatccc ccctctgcga ctctgcggag acaatgcagg tatgattgcc tatgccagcg
     9901 tcagcgagtg gaacaaagaa aacttcgcag gctgggacct caatgccaaa ccaagtcttg
     9961 cctttgatac catggaataa agagtggctc tttgtcaagt gtagtgggta gtcgaaaagc
    10021 tgcaatctgg agagtacgaa attcgtactc tcttttttga tgttcaaagt catcaaaatc
    10081 cgttttttaa aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat aatcttaatc
    10141 aaattattgg tcgcttcaag tttagcgttg gaataaggca gcttaagtgc gttgataatc
    10201 ttatctctat cccttaaaaa agtccaaaag accgtttgaa aaagcggatg aaccgttggc
    10261 agttcttgct caatcaatcc aaagaaatgg tcggcattct tctcttgaaa atgaaagagc
    10321 aggagttgat agagttcgta gtgaacctgt aatccctcag agtaagaaag cagcttatct
    10381 cgtacttccc gatgggttaa gtgcattcga aacgtgggct gatagaatcg tttctgacag
    10441 agcttgaagc tatactggtg tagtaaatca gtccagtgga ctgatttagc ccgagcctag
    10501 aaacgaaaaa gcgagggttc caaaagcgct tgagcgcccg atactccaag gattttcggt
    10561 caaattggtt catgatttgg attcgtactc ggttcatagc tcggctcaga tgttggacaa
    10621 tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag ttgcttagcg agccgataat
    10681 aagggctgta catgtccatg gtgatgacct cgaccagctc ccgaacctct ctctgatagc
    10741 gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg aggatggatt
    10801 tggactcaaa atcttgggca atgaagctca ttttgctctt tttgaagcta tactcatccc
    10861 aactcataac ttttggcaac ttggtccaat cggtttcaaa cttaaattcc ctcagttttc
    10921 ggatgacggt ggaagttgag accgccaatc tgtgggcaat ctcagtcata gactgctttt
    10981 caaggaggag ctgagcgatt ttttgtctca ccatgttgga aatctggcaa tttttcttga
    11041 caatggatgt ttgagaaacg accaccttaa ggcaattctt gcactgaaag cggcgctttt
    11101 tgagatgcag taccgtgggt aaaccctgac agtcgagaag cggaatttta gaggctttct
    11161 ggaagtcgta tttgatcatc ttcccttgac aatgaggaca aggaggagcg ggggaatcca
    11221 actttgcctg aacgactaga tgggtttggt atttcagaac agacaagatt ttgatatttt
    11281 tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg ttccatatgg accctttcta
    11341 atgagttggt tagacgcttt tcattatagg tcatatgggg ctttttttct acaagaaacg
    11401 accctataat tcctggggtg ggattaccca ctacagaaat tatagagcca aagcattcca
    11461 aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag
    11521 taaccgcgct ataacgaggt atctaccgag attgtcaatt ctccagtata ctgttataaa
    11581 aaacaaaact ggaggatttt tttatgtcct cccatcgtcc catcgactgt tccgtagctg
    11641 cccaataacg gagtatagtc ggctgaaaca agaataggac aaaagtgcct caagaaaagc
    11701 atcgtaattt gacaatatta ttctgagatg tttttgatgt aagcccatat tttctcaatg
    11761 ggattatact cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc tccttacaca
    11821 tgttcattct gtgaaacctt gcattgtcca taatgataag ggatggtgta tctaaagtag
    11881 gtagtaagaa tttttggaag caagcttcga aaaagtcact cgtcatcgta tctttatagg
    11941 tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat aacagtatcg
    12001 caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag
    12061 actaactgcc tgctcaaggc tcgatcatat ttgagataaa aataggtctc aacccctgtc
    12121 tcataaatat aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt
    12181 actttttctg ggtcttgttc gcagtaggta cggctctttt tagactatat cccatagcct
    12241 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
    12301 aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact ttttcaatta
    12361 atagtggaag ttttcttaaa gttagtgtgt tgaaacgttt ttatacagtg ctaaaatttg
    12421 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
    12481 aagagaaaat aggtatcttt gagatataag tatgatttac tataaaatta ttgagttatt
    12541 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
    12601 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
    12661 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
    12721 catataattg gactttgtaa aaagcagatc agaaggatgt ctccatatcc tattttgata
    12781 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
    12841 gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa tattttaaaa
    12901 ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt tttatatatg
    12961 ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac atgccatgga
    13021 tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg gacatattct
    13081 atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga gagtataata
    13141 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
    13201 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaaatcat
    13261 ttgttatgtt ggaaggttgg atccagaaaa aaggccggat agattccttg aatttgcaga
    13321 aaaattattt ttagtcagag aagatgtgat ttttattatg gctggaaatg gtagtatgtg
    13381 ggctactttg aaagaaaaaa tttgccattt gaaatgtaga gataatttca ggttacttgg
    13441 tgaaatctat ccagctacta tagtttacca aatatcggat ttattgtata ttccttctga
    13501 tacagaagga atacctatgt gtgttttaga gtcaatgtca caagaaactc cggttttagc
    13561 tagtaatgtt ggcgggttaa gtgaaattat tgaacatagg gttgatggat ttttatttga
    13621 gaaggaagat gttgagggag tgtgtgcttg tgctaatttt ttactcaatg attctgagta
    13681 tttgaaatat ataggtgaga atagtaaatc aaaaataaga aaacattttt ctgtgcaaaa
    13741 aatgtttgta gaaaccatga gagtatatga tgaattatta gagaagagta gtcatggata
    13801 ggaatataga tcaagaatta gtaagtatta taataccaac acataatagg tatgaatctc
    13861 tgattagagc tgtgaaaagt tgtttacatc aaagttataa aaatatcgaa gttataatta
    13921 ttgatgataa ttatagtaat gtaaatttaa gaaataaaat tatccatcaa tttggctata
    13981 ccagtcatag aattaagtta attttaagta atgaagattt aggtgcaact aatgccagaa
    14041 acataggtat caaaaattct agaggtaagt atatatcatt tttagacgat gatgatgaat
    14101 atatgccaga tcgaatttta aagttgatgg cttgttttaa aaagagtaga atgaagaatt
    14161 tagctttagt ttatagttat ggaataataa tttatccaat aggaaatatt ttaatttatt
    14221 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
    14281 actattaata ggagacaaat gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa
    14341 aatttttaac gaatttcttt ttcgaaatat atgttattat atcattttgg ttttttctat
    14401 tgtatatatg acaactatgt tcaattaaaa tttagaaagt gagaaactat tgtgtatact
    14461 attataaaat caaatataaa aaaatttagt ttattaacga tatttattgt tgctggtcaa
    14521 ttattgctaa tttatgcagc aactattaat gctctggtgt tgaatgaatt aattgcgatg
    14581 aatttagagc ggtttttgaa attgtcaatc taccaaatga ttgtctggtg tgggataata
    14641 ttccttgact gggtagtgaa aaattatcag gttgaagtga tccaagagtt taatctagag
    14701 attcgaaata gagttgccac agacatctct aactctacct atcaagaatt tcatagtaaa
    14761 tcatcaggaa catatctttc gtggctaaat aatgatgttc agactttaaa tgatcaggct
    14821 tttaaacaac tttttttagt aataaaagga atttctggta ctatatttgc agttgtgact
    14881 cttaatcact atcattggtc attgactgta gccaccttgt tttcattaat gattatgcta
    14941 cttgtaccaa aaatctttgc atcgaaaatg cgagaagtta gtctaaattt aactaaccaa
    15001 aatgaagctt ttttaaaatc tagtgagact atattgaatg gatttgatgt gttagcgtcc
    15061 ttgaatcttt tatatgtatt gcctaagaaa attaaagaag caggaatttt attaaagatg
    15121 gttatacaaa gaaagacaac tgtagaaacg ttagcaggcg ctattagctt ctttctcaat
    15181 attttttttc agatatctct cgttttttta acaggctatc ttgcaataaa aggaatagtg
    15241 aaaattggta ctattgaagc aataggagca ctaacaggtg ttatttttac agcgctaggt
    15301 gaattaggag gtcaattatc ctctattatt ggtacgaagc ctattttttt aaaattgtat
    15361 tcaattaatc caattgagtc aaataaaatg aatgatatcg aaccaaatga ggtgaataga
    15421 gattttccgt tatatgaagc aaaaaatatt tgctataagt atggagataa agaaatatta
    15481 aaaaacttaa atttttgttt tcaacgtaat gaaaagtatt taattttagg tgaaagtgga
    15541 agcgggaaat ctacattatt aaaattattg agtggctttt tgagagatta tagtggagaa
    15601 ttgcgattct gcggggatga tataaaaaaa acctcctatt taaatatggt ttcgaatgtt
    15661 ctatatgtag atcaaaaagc ttatttgttt gaaggtacga ttagagataa tattttattg
    15721 gaagaaaatt atactgatga agaaatacta cagtctttag agcaagttgg tttgagtgta
    15781 aaagattttc ctaataacat tttagattat tatgttggtg atgatgggag attactgtca
    15841 ggagggcaga aacaaaaaat tactttagct agagggctaa ttagaaataa gaaaatagta
    15901 ttaattgacg agggaacttc tgctatcgat aggagaactt cgttagcgat tgaacgtaag
    15961 atattagata gagaggattt gactgtcatt attgttaccc atgctccgca tccggaactt
    16021 aaacaatatt ttactaagat atatcaattt ccaaaggatt ttatttaaga atatagggga
    16081 gggaaacatg agattctatt gtgaagctta tgaggtaatt actgaagaga aaaaagtata
    16141 ctttaatgat attgagttag aagttaagta ttcctctgtc gaagaattgt ttataatatg
    16201 tgagaaatta ttagataaga aaaaagtatc atttttttat gtatatgaga aacccttaag
    16261 gtatctgtta tttgactata tatttctact agttctagct aaaaaaaata tcccaatctt
    16321 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    16381 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    16441 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    16501 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    16561 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    16621 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    16681 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    16741 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    16801 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    16861 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    16921 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    16981 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    17041 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    17101 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    17161 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    17221 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    17281 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    17341 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    17401 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    17461 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    17521 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    17581 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    17641 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    17701 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    17761 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    17821 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    17881 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    17941 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    18001 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    18061 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    18121 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    18181 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    18241 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    18301 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    18361 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    18421 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    18481 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    18541 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    18601 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    18661 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    18721 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    18781 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    18841 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    18901 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    18961 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    19021 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    19081 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    19141 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    19201 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    19261 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    19321 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    19381 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    19441 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    19501 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    19561 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    19621 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    19681 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    19741 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    19801 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    19861 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    19921 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    19981 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    20041 gtcttcccaa agatactaga caattaaaaa aagaatttat agaaataaat gccccagtga
    20101 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    20161 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    20221 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    20281 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    20341 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg ggccttgaag
    20401 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    20461 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    20521 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    20581 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    20641 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    20701 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    20761 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    20821 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    20881 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    20941 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    21001 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    21061 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    21121 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    21181 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    21241 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    21301 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    21361 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    21421 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    21481 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    21541 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    21601 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    21661 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    21721 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    21781 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    21841 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    21901 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    21961 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    22021 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    22081 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    22141 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    22201 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    22261 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    22321 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    22381 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    22441 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    22501 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    22561 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    22621 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    22681 atgacaagtt tatctaaagt taagagatac tatcttgatg ttcttgtttc cgctgccata
    22741 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    22801 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    22861 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    22921 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    22981 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    23041 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    23101 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    23161 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    23221 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    23281 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    23341 ttgaagacat gatttatcgt ggattggtga tgacagctct ggaaaaagga aagaaatggg
    23401 ggctagatgt acttggttct gctattttat ttggggtctc gcacattagt aatcacggtt
    23461 gggtcttgac agactttttc gtctatatgg gtggcggact tatatttgca gtcttattta
    23521 gaatgacaaa gtccatttat tggcctattg ggctgcatat agtctacaac ggcattggtc
    23581 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt tctggggaaa
    23641 gattcccatt tgaacttaag aaggagttgt gatgaaagta tttcttcaaa atagagattt
    23701 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    23761 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    23821 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    23881 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    23941 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgct
    24001 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    24061 tagaattatt gggcaagacc atctggcaga agctattgga tttaaacagt caactgttag
    24121 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggcattc tatccatcca
    24181 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    24241 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    24301 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    24361 cttggttttg tttattatct ctactagtca agcagtgata aatgttacgg ttcctatttc
    24421 cactctattt ttaaggaacc agcccttttt gaatttacaa actggtcaat ctcttgcctt
    24481 gttagccaca ctagaattat cagcccttat tttgggaagt ctgatgagtg gctatctgca
    24541 acataccatt tccataaaaa tagccctgta tgcttcactc ctactccaat tactactcct
    24601 agtgggcttt gcgacagctc attttggctt gattctgatc tttagctttt tggatgcctt
    24661 tttcgcgggt attctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    24721 gtcaatggga gcagttcaat cttctatcgg tgccattacg gttgttttac ctagcttatt
    24781 tacaatagct ttgggaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    24841 attactattt cttctagttg cctttgtcat gcttctgaat attcgtgaaa gtatttagtg
    24901 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    24961 caacagactt tttctctttt ctgaatgtgt tatagtagac tgaatctaaa atagtacgaa
    25021 ataattgcta aaacatttat agaaattaat tttactttcc caatcgattt gttctcatct
    25081 tatttcaatc tgctatataa tagtccatgc tgtggctgga ttcttttcag cctacttata
    25141 ctcttcgaaa ctctcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac
    25201 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc
    25261 tgcaacctca aaacaatgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
    25321 tttcattgag tattattaag acaatatgag gagaaagatg aaagaaaaag gattttagga
    25381 gggggcgcag gcagccatgc caacggctct tggctatgtc agtatcggcc tggcctgtgg
    25441 gactatcggt gcgccctatg tgacacctgt tgagatgggc ttgatgagtc tctttgttta
    25501 tgctgggagt gcccagtttg ccatgttggc actgattgtg gttcaagctc ctgtggcagc
    25561 tattgctatg acggtttttc taatcaactt gcgtctcttt ttgttgagtt tacacgcatc
    25621 gacttatttc cgtcatacca gtctttggta caatatcggt atgtctagta tcttgacaga
    25681 tgagacctat ggcgttttga tgggtgaatt ggcccataca gacaaggtaa atcctatgtg
    25741 gatgcacgga aacaatctta acagctatgt ggcttggttt gtggggacag tagtcggaac
    25801 ggctctgggt ggcctgctac caaatccaga aatctttggc ttggattttg ccctggttgg
    25861 gatgtttatt ggtatttttg cttcgcaatt tcagattatg caaagacgga ttcctgtccg
    25921 caatctgctc attatcctag cagttgttgc ggtgtccttc tttttgctct tgacagtggt
    25981 gtctcagtca ctagctgttc tgtttgcgac gctacttggt tgtagcatgg gggtggtttt
    26041 agatggtcag taagtatctt ttattagcag ttattttctc tgacttggtg acttggattc
    26101 tccgtatgat tcccttcatc ttagtcaagt ataagggctt gcctgcaatc gttgagcgtt
    26161 ttttgaagtt cttgcccgtt tccattatct ttgccttgat tctttcaagc gtagtgacag
    26221 gtaaggttgg gagccttcct caaattaaat ggctagactt cttagccgtc tttccaacag
    26281 cttgggtagc ctttcgctac cgcaatctag tcggaacagt tctctttgga gtagtcttga
    26341 ttgccgtctt gcgtttggtc ttttaaatca gccataaaga aaacctatca cagatatata
    26401 tatcatataa tggtgtaaat gatttttttc tgttaagatt ataaggtatt ctattttgga
    26461 ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg ctgccctagg gcttgttgct
    26521 gcaggtgtgc tagcagcttg ctccggtggt gctaagaaag aaggacaagc agctagcaag
    26581 aaagaaatta ttgttgcaac taattcttca ccaaaaccat tcaactatga agaaaatggc
    26641 gaattgactg gttacgagat tgaagtcgtt cgcgctatct ttaaagactc tgataagtat
    26701 gatgtcaagt ttgagaagac agagtggtca ggtgtctttg cgggtcttga cgctgaccgt
    26761 taccaaatgg ctgttaacaa catcagctac actaaagaac gtgcggagaa atacctttat
    26821 gcagccccaa ctgttaaaga ccctaacgtt cttgtagtca agaaagacga ttctagcatc
    26881 aaatcgcttg atgatgttgg tggaaaatca acagaagttg ttcaaggaac aacatctgct
    26941 aaacagttag aagactacaa caaacaacac tcagataatc caactatcct taactatact
    27001 aaagcaaact tacaacaaat catgggccac ttgagcgatg gtcagtttga ctacaagatt
    27061 tctgataaaa tcactgttga aacagtcatc aagaaccaag gtttggacaa cttgaaagtc
    27121 atcgatcttc caagcgacca acaaccttac gtttacccac ttcttgctaa aggtcaagat
    27181 gagttgaaaa catttgtaga caaacgtatc caagaactct acaaagacgg aactcttgaa
    27241 aaattgtcta aacaattctt cggagacact tacctaccgg cagaagctga tattaaataa
    27301 tttcttgaaa tcatccattc tgagtaagat gggtgatttt tcagttcgct accgcaatct
    27361 agtcggaaca gttctctttg gagtggtctt gattgccatc ttgcgtttgg tcttttaaat
    27421 tacccataaa aaaaacttat cacagagata gatatcatat aatggcgtaa atgctctttt
    27481 tctgttaaga ttataaggta ttctattttg gaggaaatga catgaaaaaa atcgttaaat
    27541 actcatctct tgcagccctt gctcttgttg ctgcaggtgt gcttgcggct tgctcaggtg
    27601 gtgctaagaa agaaggacaa gcagctagca agaaagaaat catcgttgca accaatggat
    27661 caccaaagcc atttatctat gaagaaaatg gcgaattgac tggttatgag attgaagtcg
    27721 ttcgcgctat ctttaaagat tctgacaaat ataatgtcaa gtttgaaaag acagaatggt
    27781 caggtgtctt tgctggtctt gatgctgacc gttacaatat ggctgtcaac aatcttagct
    27841 acactaaaga acgtgcggag aaatacctct atgccgcacc aattgcccaa aatcctaatg
    27901 tccttgtagt gaagaaagat gactctagta tcaagtctct cgatgatatc ggtggaaaat
    27961 cgacggaagt cgttcaagcc actacatcag ctaagcagtt agaagcatac aacgctgaac
    28021 acacggacaa cccaactatc cttaactata ctaaggcaga tttccaacaa atcatggtac
    28081 gtttgagcga tggacaattt gactacaaga tttttgataa aatcggtgtt gaaacagtga
    28141 tcaagaacca aggtttggac aacttgaaag ttatcgaact tccaagcgac caacaaccgt
    28201 acgtttaccc acttcttgct cagggtcaag atgagttgaa atcatttgta gacaaacgca
    28261 ttaaagaact ctacaaagac ggaacgcttg aaaaattgtc taaacaattc ttcggagaca
    28321 cttatctacc ggcagaagct gatattaaat aatttcttga aatcatccat tctgagtaag
    28381 atgggtggtt tctcagtttt tagggatata gttttaaact atatatctga ctatctaata
    28441 acaatttgtg aaatcaaaca aattgtgaga tactagtacg gtattatttt taaggagaaa
    28501 gaatcatgaa aatcaaaaaa tggcttggcc tagcagccct tgctacagtc gcaggtttgg
    28561 ctcttgcagc ttgcggaaac tcagaaaaga aagcagacaa tgcaacaacg atcaaaatcg
    28621 caactgttaa ccgtagcggt tctgaagaaa aacgttggga caaaatccaa gaattggtta
    28681 aaaaagacgg aattaccttg gaatttacag agttcacaga ctactcacaa ccaaacaaag
    28741 caactgctga tggcgaagta gatttgaacg ctttccaaca ctataacttc ttgaacaact
    28801 ggaacaaaga aaacggaaaa gaccttgtag cgattgcaga tacttacatc tctccaatcc
    28861 gcctttactc aggtttgaat ggaagtgcca acaagtacac taaagtagaa gacatcccag
    28921 caaacggaga aatcgctgta ccgaatgacg ctacaaacga aagccgtgcg ctttacttgc
    28981 ttcaatcagc tggcttgatt aaattggatg tttctggaac tgctcttgca acagttgcca
    29041 acatcaaaga aaatccaaag aacttgaaaa tcactgaatt ggacgctagc caaacagctc
    29101 gttcattgtc atcagttgac gctgccgttg taaacaatac cttcgttaca gaagcaaaat
    29161 tggactacaa gaaagcactt ttcaaagaac aagctgatga aaactcaaaa caatggtaca
    29221 acatcattgt tgcgaaaaaa gattgggaaa catcacctaa ggctgatgct atcaagaaag
    29281 taatcgcagc ttaccacaca gatgacgtga aaaaagttat cgaagaatca tcagatggtt
    29341 tggatcaacc agtttggtaa taagaaacag ggaggtggga gagaaaattc cacctcttgc
    29401 ttttgtatag agtatagatt gtaaagaaga ctattcgttc atagaaaggt agagagaata
    29461 tggtttttcc tagcgaacaa gaacagattg aaaaatttga aaaggatcat gtagtccaac
    29521 attattttga ggttttgcgt accttgattt ctaagaaatc agtctttgcc cagcaggttg
    29581 gactcaagga agtcgcaaat tatctgggtg agattttcaa gcgtgttgga gctgaagtgg
    29641 agattgatga gagctataca gcgccctttg tcatggcaca tttcaagagt tcgcgtccag
    29701 atgccaagac cttgattttc tataaccact atgacactgt gccagcggat ggggatcagg
    29761 tctggacaga ggatcctttt acgctttcgg tccgcaatgg cttcatgtat gggcgtgggg
    29821 ttgatgacga caagggtcat atcacagctc gcttgagtgc tttgagaaaa tatatgcagc
    29881 accatgatga tttacctgtc aatatcagct ttatcatgga gggagcggag gaatcggctt
    29941 caacagacct agataagtat ttggaaaagc atgcagacaa actccgtggg gcggatttgt
    30001 tggtctggga acaagggacc aaaaatgcct tggaacagct ggaaatttct ggtggcaata
    30061 aggggattgt gacctttgat gccaaggtaa aaagcgctga tgtggatatc cactcgagtt
    30121 atggtggtgt tgtggaatca gctccttggt atctcctcca agccttacag tctcttcgtg
    30181 ctgcggatgg ccgtatcttg gttgaaggct tgtacgaaga agtacaagag cccaatgaac
    30241 gagaaatggc cttgctagaa acttatggtc aacgaaaccc agaggaagtt agtcggattt
    30301 atggattgga gttgcctctc ttacaggagg agcggatggc ctttctaaaa cgtttctttt
    30361 tcgagccagc gcttaatatc gaaggaatcc agtctggtta tcaaggtcag ggtgttaaga
    30421 ctattttacc tgcagaagcc agtgccaagc tagaggttcg tctggttccg ggcctagaac
    30481 cgcatgatgt tctggaaaaa attcggaaac aactagacaa aaatggcttt gataaggtag
    30541 aattatacta taccttggga gagatgagct atcgaagcga tatgagcgca ccagccattc
    30601 tcaatgtgat cgagttggcc aagaaattct atccacaggg cgtttcagtc ttgccgacga
    30661 cagcggggac aggacctatg catacggtct ttgatgccct agaggtacca atggttgcat
    30721 ttggtctagg aaatgccaat agccgagacc acggtggaga tgaaaatgtg cgaatcgctg
    30781 attattacac ccatatcgaa ttagtagagg agctgattag aagctatgag tagagatatt
    30841 atcaagttag atcagatcga tgtgactttt caccaaaaga agagaaccat cacagcggtt
    30901 aaggatgtga ccattcacat ccaagaaggg gatatctacg gaatcgttgg atattctgga
    30961 gcagggaaat caacccttgt acgggtgatt aacctcttgc aaaaaccatc tgcagggaaa
    31021 attaccattg acgacgatgt gatttttgat ggtaaggtca ccttgacggc agagcagttg
    31081 cgtcgtaaac gtcaagatat cgggatgatt ttccagcatt ttaacctgat gagccaaaag
    31141 acagcagagg agaatgtagc ctttgccctt aaacactctg gactcagcaa ggaagaaaag
    31201 aaggctaaag tagctaagtt gttggacttg gttggtttgg cagatcgtgc tgaaaactac
    31261 ccttcacaac tatctggagg gcaaaaacag cgtgtggcaa ttgcgcgtgc cttggccaat
    31321 gatccaaaaa tcttgatttc agacgagtca acttctgccc ttgatccgaa gacaaccaag
    31381 cagattttgg ccttgttgca agatttgaac caaaaattag gcttgactgt tgtcttgatt
    31441 acgcatgaaa tgcagattgt caaagacatt gccaaccgtg ttgcagttat gcaggatggg
    31501 catttgattg aagagggtag tgtgcttgaa atcttctcaa atcctaaaca acctttgact
    31561 caagacttta tctcaacagc tacaggtatt gacgaagcca tggtcaaaat cgagaagcaa
    31621 gaaatcgtgg aacacttgtc tgaaaacagt ctcttggtgc aactcaagta cgctggagct
    31681 tcaacagacg agccactttt gaatgaattg tacaagcatt accaagtaat ggctaatatt
    31741 ctctatggga atatcgaaat tctcgatggt actcctgttg gagaattggt ggtggtcttg
    31801 tcaggtgaaa aagcagcgtt ggcaggtgcc caagaagcca ttcgtcaagc aggtgtacaa
    31861 ctaaaagtat tgaagggagg acagtaagat ggaatcattg attcaaacct atttaccaaa
    31921 tgtctataaa atgggttggg ctggtcaggc aggctgggga acggctatct acttaactct
    31981 ttatatgaca gttctttcct tcattatcgg aggcttcttg gggctagtgg caggtctctt
    32041 tctcgtcttg acagcgccag gtggtgtctt ggagaataaa gtcgtattct ggattttaga
    32101 caaaattacc tcaatttttc gtgcagttcc ctttatcatc ctcttggcaa tcttgtcacc
    32161 actttctcac ttgattgtta aaacaagtat cgggccaaat gcagcccttg tcccactttc
    32221 ttttgcagtc tttgccttct ttgcccgtca ggtgcaggtt gtcttggctg aattggatgg
    32281 cggtgtcatt gaggcggctc aagcgagcgg agcgactttc tgggacatcg tgggtgttta
    32341 cctatcagaa ggtcttccag atttgatccg tgtgacgact gtgaccttga tttcccttgt
    32401 tggggaaaca gctatggccg gtgcggttgg agctggtggt atcggtaacg tagccatcgc
    32461 ttatggattt aaccgctaca atcacgatgt gaccatcttg gcaaccatca ttatcatttt
    32521 gattatcttt gcaatccaat tcttgggaga tttcttgact aagaaattga gccataaata
    32581 aaaaagagcc gcgtggctct ttttaactga tcagattttc tgtgcaaatt ttttactcaa
    32641 ggcttgtcca atcaaggcac ccactagggc tccgatgaca atacttgcga taaatagaag
    32701 gacagttcca gggtttggag cgaccatgat gcggtcgata tattcttggg attttcctct
    32761 tgccagaaga gtagccatat aggctttggg cgcaatccac ataagcaaga ttggtcctgt
    32821 tgtactaaag gcgaaaataa tgaaagaaag gaagttcttt gttttgtcct tgtattttcc
    32881 taaatgagct actccatctg ctaggaggcc acagataatt ccaggaagga aggaaccagc
    32941 accgtgttta gttcccaaga aaaagagggc aatgacaagg ccgatagtgg taatggctcc
    33001 aaagcgcgga acttttgcga ctaggatcat atagacgcta ccgccgacaa gggcagtaaa
    33061 ggcaggcgca taaaacatgt ttccagtttg gtcaaagaga ttgcccaaaa ggacaccaat
    33121 ccccatgcag aggaagtaaa gaactgcaaa aagcagtgta gttaagatag atttcttcat
    33181 gaattgtctc ctgataattt tttcacaatt ctcattttac catggtttgg tgggattgta
    33241 aatggatact agaagttttt gaaaacgctt gaaatatgat ataatggttt catagttatt
    33301 tttaggggaa tatcatgggt agatttttag actttgtctt taatcgtttc tttttaggga
    33361 tgattgcgac agccttcttt tggctattaa ctttagcagg agggattatc cttggtctag
    33421 cgccggctag tgccaccttg atgagcttat atgcagaaca tggttatagc tttcgggaat
    33481 acagtttgaa ggaggcttgg tctctttaca agcaaaattt tgtctcaagc aacctgattt
    33541 tctatagctt tttaggtgtg ggtctagttt tgacctatgg tttgtatctc ttggtgcaat
    33601 tgcctcatca gactattgtt catttgattg cgaccctttt gaatgtccta gtagttgccc
    33661 tgatcttttt ggcttataca gtatctttaa aattacaagt ttattttgcc ttgtcctatc
    33721 gaaatagtct caaattatcc ttgattggca tctttatgag tctagcagct gtggccaagg
    33781 ttctccttgg gactgtgcta cttgtagcaa ttggttacta tatgcctgcc ctgctatttt
    33841 ttgtaggaat tgggatgtgg catttcttta tcagtgatat gttggaacct gtctatgaaa
    33901 tcatccatga aaaattggcg acaaaataga atgaagcagt tttggctaca tacgcttcta
    33961 agaacctata gttcagtgat gatcattatc attgcgagtt ttgcaatctt actctcttac
    34021 gctgactggg attcacgtga aaaggaagcc cagagagtag cccagcgtgt aactgctaga
    34081 acagtgagtg aaattgaata ttaccataga gagtcaaccc agatagctca ggctttagtt
    34141 gaaaatcaag ctcgtattga gggaatctat aaatacttta gccttagcat gccagactat
    34201 ttttactggc aattagagcg gaaagcttcg ccttatatat cagtctctct gtatgaaaat
    34261 gttgatgacc tctatgttcg aaatgatttt gtaactgggg tggccattgc ttttcaagat
    34321 tacaaggaag tctatgtttc tactaaagac aaacgtagtg gagaaaaaat cagggctgag
    34381 gatttcaaac cagcaggaaa tagttttgcc attccggtgt cagatccagt gtcagatcaa
    34441 gatttaggag tgatttacat ctccttggat cctgctgttt tataccatgc cattgataat
    34501 actagaggtc atactccgat ggcagtaaca gtgacctcac cttttgatac ggagattttt
    34561 catattggtg agacagttga tagggagagt gaaaattggc tagttggctt aacttctcat
    34621 ggatatcagg ttcaggtggc agttcctaaa aactttgttt tacaaggaac agtgactagc
    34681 tctgctttga ttgtgggttt gagccttctc tttattgtca ttctttatct gactttgagg
    34741 cagacttttg ctaattacca aaagcaggta gtggatttag tggaatccat tcaagtcatt
    34801 gctcaaggcg aagaggggcg tcggattgac atttccgaaa aagatcagga attactccta
    34861 atcgcggaga cgaccaatga tatgttggat cgattggaaa agaatatcca tgatatttac
    34921 cagttagagc ttagtcaaaa agatgccaat atgcgagcct tgcaggcgca aatcaatcct
    34981 cattttatgt ataatacgct ggagttcttg cgcatgtatg cagttatgca gagtcaagat
    35041 gagttggcag atatcattta tgaattcagt agtctcttgc gtaacaatat ttccgacgaa
    35101 agagagaccc tcctcaaaca ggaattagaa ttttgccgta aatacagcta tctctgcatg
    35161 gttcgctatc ccaagtccat tgcctatggt ttcaagatag atccagagtt agagaatatg
    35221 aagattccca agtttacctt gcaaccgctg gtagaaaact atttcgcgca tggtgttgac
    35281 cacaggcgga cagataatgt gattagcatc aaggctctta aacaggatgg ttttgtggaa
    35341 attttggtgg tcgataatgg tagaggaatg tcggctgaaa agttggcaaa tatccgagaa
    35401 aaattaagtc agaaatattt tgaacaccga gccagctaca gtgatcaaag gcagtctatc
    35461 gggattgtca atgtacacga gcgttttgtg ctctattttg gagaccgcta tgccattacg
    35521 atagagtctg cagagcaagc cggtgttcag tatcgtatta caattcaaga tgagtagaaa
    35581 gggagaaaat gtataaagta ttattagtag atgatgagta catggtgaca gaaggtctga
    35641 agcgtttgat tccctttgat aagtgggata tggaggtcgt cgcaacagcc agtcatgccg
    35701 atgaagctct agaatatgtt caggaaaatc ctgtcgatgt catcatttcc gatgtcaata
    35761 tgccagacaa aacagggctt gatatgattc gggagatgaa agagatctta ccagatgctg
    35821 cctatatcct gctctcaggt tatcaggagt ttgattatgt aaaaagagca atgaacctta
    35881 gtgtggtgga ctatttggtc aagcctgttg ataaggtaga gctgggaaat ctgctggaga
    35941 agattgcagg tcagctcggc gagagaggga agaaaagtca gactcttagt caagaattag
    36001 acgaggctgg atttgttagt tatttagggg ataaggagaa ttggtggata ggtctatcca
    36061 aggaaaaaca aggttccttc accattccct actatgtctt gggccaagac tggcagattt
    36121 tcatttctga ccaaccccta gatggtttag tcgttacacc ttttgaagct ccttatcaag
    36181 aacactttga acgctggaag ctgaatgctg agaaaaccct cttttacggt tctgtaaatt
    36241 tgcagcagtc tgagagtctc tttgcctatt acgaaccgat ttatagggtt atcattcagg
    36301 gaaatctcaa tcaaatcgta gaagagttaa atctcttgga gaaggtagtt cttgaaaata
    36361 cgccgcgtgt tccgattact aaacagcttt ttattcagtt tgtcatggat gttttccatt
    36421 tatttgaaca tctcaaagct gatgacctga cagacatcgt caaaaccatt catgctattc
    36481 aatccttcga tgaattggtt ccttatatca aggaaactct gagcagcttt ttcggtcaat
    36541 accgtatgaa tgaaaatgtg gtcagtgtgc tggaagtcat tggttgtgat taccaaaaag
    36601 agctttccct caaggatatc agtaaggctc tctttatcaa tcctgtctat ctagggcagt
    36661 tgattaagcg tgaaaccgat tcgacttttg cagagttact aaacaaacaa cgtattaagg
    36721 ctgcccaaca acttttgctt tcaactagtg acagcatcga agatatttgt tatgctgttg
    36781 gttacagtaa ccttggatat ttctataaag ttttccgaaa attgtgcgga aaatcgccaa
    36841 aagcctaccg aaaacaggta gaaactatac tataagattt gtattccttt acaaaatgtg
    36901 ctataatata aatattatta ttaggaggtt ctatcatgaa aaagaaacca atttatctat
    36961 gggtcttgct aatcttgtct gcccttattt cagttccgtc tctgtttgga attgtgagtc
    37021 ccttgcctag taaagaagcc cttcgtactg ctcagaaaca agttgcaggg gtcaatgctc
    37081 agcaattaga agaccagctt aattatacct atagagtagc agaagcatct cattctattt
    37141 ttaatgttgc tttgattgtg ctatctacta ttttagtggt cgtagcgatt gtcttccttg
    37201 ttcgtaaaaa tttgcaatat gcaaactata cttacgttgg ctatgttttg ttagctatta
    37261 ttggttcgat ttatggctat gttggtttac aagacgctgt gcagttggtt caagatgaga
    37321 gcatgcgttt gacagtgagt attggttcaa aagctgttag cattttctat atcgtcatca
    37381 atgttctctt cctagccctt gtcttctata agatgtggcg acaacagaaa gcctcggcag
    37441 aagaagagga aacagaagag cttgcctaag tattgacaaa aaagaactat caagatacaa
    37501 tcttggtagt tgttttttga ttatagataa aatcatggag gtacatatga agataatttc
    37561 tttagtttat attagtttga gtggcaacac tgaaagtttt gtgacgcgct tgaaagacta
    37621 tctcttgtcc cagtacaaag ggattgaggt tcaaaagatt catatcaagg atttagtcaa
    37681 ggaaggcaaa aatttctatg aaatggacca tccctatgtc gcttttttgc cgacctatct
    37741 cgaaggtggg aatggcgtgg ataacggaga tgttgagatt ttgacgacac cggtgggaga
    37801 ttttattgcc tatggtaaca atgctagtaa gtgttttggt gtggttgggt caggaaatcg
    37861 taactttaat aaccaatact gcctaacagc caagcaatac agtcaacgct ttggctttcc
    37921 tgtattggct gactttgaaa tgcgaggcat gctggaagat atcaaacatg tcgcagctat
    37981 tatcgcagat ttgtatgagt tggaaaagga gaattaatac tcaatgaaaa tcaaagagca
    38041 aactaggaag ctagtcgcag gttgctcaaa gcacagcttt gaggttgcag atagagctga
    38101 cgtggtttga agagattctc gaatagtata aaattcttat aagaggtggt tgaagttgtt
    38161 caactgtttt ttgagtataa acagtcttta agaacgtaaa aaagcataag ttcaggtctt
    38221 caaaaccttg ttcttatgct ttttatcata gaaatatttg ctgaattttc tcttgaaatg
    38281 aaaccttatc ttcatctcgc gcttgtccct taccctgctt ttccgattgc gagtgcgtag
    38341 ataaagaaga tggcgaagcc aaagaggaaa atcaatcccg caatggcaag gtgtttgagc
    38401 caagaaggaa gatttttgtt ttcacgcgtt accaaggcgt aattcaaaag agcaaagaaa
    38461 ggtgttgtca ggaaagagcc aatcatggca aagcggagca tggttgaaac ctgaccagag
    38521 aagaacttga taatgacgat accgatgata gcagtgatgg tcatccagat gttcaaagat
    38581 ttacgattgt cctctttttg actgattagc agtcggagag attcctgatt aacgcgagaa
    38641 tagccatcga taacagttat aactgttcca aagatacaga ggaaggcaat aaaggtaatc
    38701 aagtaacggg accattcgcc aagaacagag gcatacatgc ccacgaattg agagatgtat
    38761 ttggctgaag cagcttcaac cgcctgccct gtaggatact gaatcagtgc tcccagtgcc
    38821 acaaagaaga cggctaggat agctgttcca atataaccag tgttaaagtc aaacagagcg
    38881 tcttctgtgt taaagttgac ggtctttctc ttttcagctg accaaagtga attgatggct
    38941 gaaatttcaa taggagccgg catccatcct aggagggaga cgatgaaggg cagagctgcc
    39001 atttgccaag gtgtcttctc gacaaaatca gaactgtatt ctggatgctt gaccgccgca
    39061 atgataactg ccagaacagt cgcaatggtt aaggcagaca taatccattt gaccatgccg
    39121 tctaaaagtt tgtagcctcc aaagagtagc atagcccaaa tgattgcaac gagaatgagg
    39181 gaccactgag taatgctaag tccaatcatt gggaaggcac tggcgatgat agctgagcac
    39241 agaatggcaa caccagccgt gttgaccata gccgaaaaga cattgaggat aaagaaaatc
    39301 cagagataga gttttccttt ttcggcataa ccttcaacca aagtctttcc agtatcagct
    39361 gtgtattcag caccaaaacg gaaaaatgga tatttaaaga cattggctaa gatgaccaag
    39421 agaagtagag accaaccgta agaaccgcca gcttgagttg aggatacaat gtgggaacct
    39481 ccaacagcgg cagttgccat taggattcca ggtcccattg cttttagctt gcttgcccag
    39541 gttgattgat ttaaggaaat agcttgcgac atgataaata ctcctttttg aattttcaga
    39601 ataatctgta tatgtaatct atattctaca aaaaattttg gaaaaatgca agaatatttt
    39661 gaaaaaagat agaaaattta caaagaaaat
//
LOCUS       DAVBED010000013        38639 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBED010000013 DAVBED010000000
VERSION     DAVBED010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.013"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            186..632
                     /gene="rplM"
                     /locus_tag="VQ547_000692"
     CDS             186..632
                     /gene="rplM"
                     /locus_tag="VQ547_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2542574.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            652..1044
                     /gene="rpsI"
                     /locus_tag="VQ547_000693"
     CDS             652..1044
                     /gene="rpsI"
                     /locus_tag="VQ547_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2542575.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            1393..1602
                     /locus_tag="VQ547_000694"
                     /pseudo
     CDS             1393..1602
                     /locus_tag="VQ547_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1758..2096
                     /locus_tag="VQ547_000695"
     CDS             1758..2096
                     /locus_tag="VQ547_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2542576.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            2286..3722
                     /locus_tag="VQ547_000696"
     CDS             2286..3722
                     /locus_tag="VQ547_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2542577.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            3774..4013
                     /locus_tag="VQ547_000697"
     CDS             3774..4013
                     /locus_tag="VQ547_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2542578.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            4143..4457
                     /locus_tag="VQ547_000698"
     CDS             4143..4457
                     /locus_tag="VQ547_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2542579.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            4575..6554
                     /locus_tag="VQ547_000699"
     CDS             4575..6554
                     /locus_tag="VQ547_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2542580.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            6564..6878
                     /locus_tag="VQ547_000700"
     CDS             6564..6878
                     /locus_tag="VQ547_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2542581.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            6909..7415
                     /locus_tag="VQ547_000701"
     CDS             6909..7415
                     /locus_tag="VQ547_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542582.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            7495..8841
                     /gene="celB"
                     /locus_tag="VQ547_000702"
     CDS             7495..8841
                     /gene="celB"
                     /locus_tag="VQ547_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2542583.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            9221..9397
                     /locus_tag="VQ547_000703"
     CDS             9221..9397
                     /locus_tag="VQ547_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542584.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9807..12020
                     /locus_tag="VQ547_000704"
     CDS             9807..12020
                     /locus_tag="VQ547_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2542585.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12242..12718)
                     /locus_tag="VQ547_000705"
     CDS             complement(12242..12718)
                     /locus_tag="VQ547_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2542586.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            12941..16141
                     /locus_tag="VQ547_000706"
     CDS             12941..16141
                     /locus_tag="VQ547_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2542587.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ547_000707"
                     /pseudo
     CDS             16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ547_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17285..17914)
                     /locus_tag="VQ547_000708"
     CDS             complement(17285..17914)
                     /locus_tag="VQ547_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2542588.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(17924..18925)
                     /locus_tag="VQ547_000709"
     CDS             complement(17924..18925)
                     /locus_tag="VQ547_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2542589.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(18956..19597)
                     /locus_tag="VQ547_000710"
     CDS             complement(18956..19597)
                     /locus_tag="VQ547_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2542590.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19616..20431)
                     /locus_tag="VQ547_000711"
     CDS             complement(19616..20431)
                     /locus_tag="VQ547_000711"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2542591.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20702..21130
                     /locus_tag="VQ547_000712"
     CDS             20702..21130
                     /locus_tag="VQ547_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2542592.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            21142..22332
                     /locus_tag="VQ547_000713"
     CDS             21142..22332
                     /locus_tag="VQ547_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2542593.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22343..22834
                     /locus_tag="VQ547_000714"
     CDS             22343..22834
                     /locus_tag="VQ547_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2542594.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            22849..23628
                     /locus_tag="VQ547_000715"
     CDS             22849..23628
                     /locus_tag="VQ547_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2542595.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            23615..24433
                     /locus_tag="VQ547_000716"
     CDS             23615..24433
                     /locus_tag="VQ547_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2542596.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            24433..24726
                     /locus_tag="VQ547_000717"
     CDS             24433..24726
                     /locus_tag="VQ547_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2542597.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24748..26649
                     /locus_tag="VQ547_000718"
     CDS             24748..26649
                     /locus_tag="VQ547_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2542598.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26709..27710
                     /locus_tag="VQ547_000719"
     CDS             26709..27710
                     /locus_tag="VQ547_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2542599.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27820..28155)
                     /locus_tag="VQ547_000720"
     CDS             complement(27820..28155)
                     /locus_tag="VQ547_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542600.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28166..28408)
                     /locus_tag="VQ547_000721"
     CDS             complement(28166..28408)
                     /locus_tag="VQ547_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542601.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28419..28961)
                     /locus_tag="VQ547_000722"
     CDS             complement(28419..28961)
                     /locus_tag="VQ547_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2542602.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(28977..29171)
                     /locus_tag="VQ547_000723"
     CDS             complement(28977..29171)
                     /locus_tag="VQ547_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542603.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ547_000724"
     CDS             29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ547_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2542604.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ547_000725"
     CDS             30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ547_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2542605.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ547_000726"
     CDS             30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ547_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2542606.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            32874..33854
                     /locus_tag="VQ547_000727"
     CDS             32874..33854
                     /locus_tag="VQ547_000727"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2542607.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            34463..36568
                     /locus_tag="VQ547_000728"
     CDS             34463..36568
                     /locus_tag="VQ547_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2542608.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            37291..38310
                     /locus_tag="VQ547_000729"
     CDS             37291..38310
                     /locus_tag="VQ547_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2542609.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            38323..>38639
                     /locus_tag="VQ547_000730"
     CDS             38323..>38639
                     /locus_tag="VQ547_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542610.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
BASE COUNT        12300 a         6338 c         8241 g        11760 t
ORIGIN      
        1 agttactttg agaagttacc gaaaaatatt tttcatatct attgactttt aggggtgaaa
       61 tttggtatga tagtaggcgg tattgtttac cccatttgaa aggccccgga accttccaaa
      121 tacttttcga tgggaaggaa cacccatcac cgtaaacaaa aatcgaacta tatataggag
      181 aaatcatgaa caaaacaaca tttatggcta aaccaggcca agttgaacgt aaatggtacg
      241 tagttgacgc aactgatgta ccacttggac gtctttctgc agtagttgct agcgtacttc
      301 gcggaaaaaa caaaccaaca tttacaccac acactgatac aggtgacttc gtgattgtta
      361 tcaatgctga aaaagttaaa ttgactggta aaaaagcaac tgataaaatc tactacactc
      421 actcaaacca cccaggtgga ttgaaacaaa tctctgcagg tgaacttcgt tctaaaaatg
      481 cagtacgttt gattgagaaa tcagttaaag gtatgcttcc acacaataca cttggacgcg
      541 ctcaaggtat gaagttgaaa gtatttgttg gagctgagca cactcatgct gcacaacaac
      601 cagaagttct tgacatttca ggacttatct aaggaaagga acaaataaag tatgtcacaa
      661 gcacaatatg caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca
      721 ggaactggta aaatcactgt taacaaaaaa gatgttgaag agtacatccc acatgctgac
      781 cttcgtcttg tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt
      841 ttcgttaacg ttgtaggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc
      901 gctcgtgccc ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt
      961 cttacacgtg actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa
     1021 gcatcacaat ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt
     1081 cggggtgttc tttttttata ctttcttact aaattggtgc aattgacaca gttgttgcga
     1141 ctttagttgc ttacaaatgt ggctgcaacc tgacaaggtc agttgcctca aaacgctaat
     1201 caatacaatt atatcaatgt ttcaaagcac tcaaaggttt gccctatggg tgcttttttc
     1261 gtgttttttt gaaaagttta ccttattttt atagtaaggt gaaataagaa taggacaaac
     1321 cgaggatagt caaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt
     1381 tcaatctact atattatgga taatgcaaga ttccatagaa tgggtaagtt agaactcttg
     1441 tgtgaagagt ttgggtataa acttttacct cttcctccct actcacctga gtacaatcct
     1501 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
     1561 accttttatg aggctctttt gtcttgttct tgtttcaatt gactataaat cgctataaga
     1621 aaaaatcatt ttattggtat aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt
     1681 agttcataaa aaacaagttt agatcctcat ctaaacttgt ttttttaaaa ttgaaggatg
     1741 attttggagg atatgagatg acattgacta ttcatgtata ttataaaggc gatggagatt
     1801 gtgcaataaa gtttgcaaga gaaatgcttg aatctgggct tgtcgcagaa attagatgtc
     1861 aaaaaggtaa tttgaaatac gaatattttt taccaattga aaaagaggga attattctcc
     1921 ttattgatca gtggataaat caagaagctt tagatgaaca tcatcaatca aatacaatgc
     1981 agaaaatctt agatttaaga aaaaaatatc acttgcagat gcaagttgaa cgttatatag
     2041 aagatgattc tgggatgcca gaaagcgata agtcgtttat agacacaggg aattagaatt
     2101 attgtgagag tttttgtagt ttgaaagtat tgaaaatcgt aaagatatca ttacgagaat
     2161 acaagaagat attgttctat ttccattaaa aattacttct ttccttaata ataaggaaaa
     2221 agaatacgtt ttcatctttt ggtttgaggt ttataataag aatatcaaag tcaggaggaa
     2281 aaaagatgac tacttttaaa gatggatttt tatggggtgg tgctgttgct gctcatcaac
     2341 ttgaaggcgg atggcaagaa ggtggcaaag gaattagtgt tgctgatgtt atgactgctg
     2401 gtcgccatgg agtagctcgt gaaattactt tgggagtttt agagggtaaa tattatccaa
     2461 atcatgaggc gatagatttt tatcatcgtt ataaagaaga catagcactt tttgctgaaa
     2521 tgggattcaa gtgcttccgt acctctattg catggacacg tatctttcca aaaggtgatg
     2581 agttagagcc gaatgaagaa ggattacagt tttatgataa tctttttgat gaatgcttaa
     2641 agaatggtat tgaacctgtc atcactctat ctcattttga aatgccttat cacttagtga
     2701 ccgaatatgg tggttggaaa aataggaaat tgattgattt ctttgctcgt tttgcagaag
     2761 tcgtatttaa acgttacaaa gataaggtta aatattggat gactttcaat gaaatcaata
     2821 atcaagcgaa ttatcaggaa gattttgcac catttactaa ctcaggtatt gtatatgagg
     2881 aaggtgataa tagagaagca attatgtatc aagcagcaca ttacgaatta gttgcttctg
     2941 cacgagctgt aaaaattggt catgagatta atccagattt tcaaataggt tgtatgattg
     3001 cgatgtgtcc aatttatcca gttacttgca atcctaagga tatcttaatg gcaatgaaag
     3061 ctatgcagaa gcgttattat tttgctgatg tgcatgtttt aggtaaatat cctgagcata
     3121 ttttcaagta ttgggaacga aaaggtattt cagttgattt tactgaccag gataaagaag
     3181 atttacttgg tgggactgta gattacattg gtttcagtta ctatatgtcc tttgctatag
     3241 actctcatcg tgaaaataat ccttattttg attatcttga aacagaagat ttagtgaaaa
     3301 ataattatgt taaggcttct gaatgggagt ggcaaattga tccagaaggt ttacgttatg
     3361 cgttaaattg gtttacagac cactatcact taccactctt tattgttgaa aatggttttg
     3421 gagctataga tcaagttgca gcagatggta tggtacatga tgattataga attgaatatc
     3481 taggtgccca tattcgtgaa atgaaaaagg ctgtagttga agatggtgtt gatttaatgg
     3541 gttatactcc atggggatgt attgatttgg tttcagctgg taccggtgaa atgcggaaac
     3601 gttatggctt tatttatgta gataaagatg acaatgggaa gggaagttat aatcgttccc
     3661 cgaaaaaatc ttttggctgg tataagaaag ttattttatc taacggtgaa tcagtagaat
     3721 agtataaaca aactgagatt attctcagtt tgtttagcat attgaggaga catatgattg
     3781 gaagtattgc agcaatttta acaacatttg catttttacc acaagttttt cgtgtagtta
     3841 agacaaagga cacaggatct attgctctag gtatgtatgt tatgcaagtt attggtattg
     3901 cattgtggct tgctcatggt attcgtatag gagacttgcc tttgatttta gcaaatagtg
     3961 tttcatttct actctcagga ataattttat tttataaatt gaagtataaa taattttttt
     4021 ccatatcatt taggaaaatg agggaattgt cattgaaaac gctttatttt ataataaaaa
     4081 tagataacaa ataagccaac ttagcacagc tttgattgga tttaagaaaa ggagaaaata
     4141 ttatggcaaa agctttaatt atttgtgcag caggaatgtc ttcatcactt atggcacaga
     4201 aaacaacaga gtttctaaaa ggaaaaggga aagatattgt agttgatgct attagtgcta
     4261 ctgaaggagg gaaagctatc gcagcagcag cttttgattt gtatcttgtc agtcctcaaa
     4321 caaaaatgta ctttaagcaa tttgaagagg ctggttctaa agcaggaaaa ccagttgtac
     4381 aaatacctcc tcaagcctat attcctattc caatgggaat tgaaaaaatg gctaatttga
     4441 ttcttgagaa tatttgatga acacatgaaa tgtcaataaa tatttaagtt aagataaatt
     4501 gttttgagtt tgatataaat tgatttaagt gtataatatg cttcaatata tgaaaacata
     4561 cgttttagga gggaatgaat gtgttaaaca ttaaagagaa agatatcctt caatttttaa
     4621 taaaaaataa ggaacgtttt gttacaagca aagaactggc agaatattta tcctgttcag
     4681 atagaactgt ccgtaatgta ctgaaattaa ttgagaagac aatgattatt caaggagtcc
     4741 ggttgatttc aaaacaaggt caagggtatc aaatattttt tgagaatcaa ggcgcttacc
     4801 aggagtttag acaaacttat gaactggaag aagactatac gaaaactgcg gtttcaaaag
     4861 gtgatgatcg tttagtattt atcttaaata aattattatt tgagcaagtt ccagttcttt
     4921 ttgatgattt agctgatgaa ctttacgtta gtcgttcaac attatctcat gatttcagaa
     4981 agatacgagt gatgttatca gagtataatt tgtccattga gagtagggcg aataaaggag
     5041 tttatgtctc aggcgaggaa cgtgataaac gacgttttat cataaattat ttcctagaga
     5101 atcaattttt taaaacaata cattgctatg taaaatttaa cttttttgct caaactgttc
     5161 cattagaaga atttgctaga attgttttgg atgaatgcca agaggccaac ctaaaactat
     5221 ctgattttgt actacagaat ttagtagttc acatagcatt gtctgtgatt cgtttaaaat
     5281 ccggatttga aataaaaaat atagactgtc agatgactga tgatgcaata gagagaaagg
     5341 ttgctcaaag aattctttct aaagtaagag aagtaacaaa tcaggaattt ccagttcagg
     5401 aaatagacta cattactttg catttgttag ctaagagtca acaatgtcaa aaaaatcaga
     5461 agaatatttc tgaagaagtt ttaaaaaaat ctttatttaa aacatttcag aatttaggat
     5521 tagatgatat gtataacttt tcttcagatt tccaactaat tgaaggattg ataactcatc
     5581 taatgacact acaagtacgt ttagaaagcc ggattacctt aaataaccct ttggtagatg
     5641 aaattaaaca gaattatagt gatatattct ttatgactag agaaattctt gcaaatatgg
     5701 acaagttctt ggagtggaca atatcagatg atgaagtagc atatgtaagt cttcactttt
     5761 tagctgctat ggaacgtagc aaagagagta ctaagtttaa tattcttgct atttgtgcaa
     5821 caggatttgg tgcagcccaa atgttaagaa atcgtttgga aacggagttt gggaagcgag
     5881 tagaagttgt tgatgtaata ggctattatg aattgaatca agaaaaactt aaaggaatag
     5941 attttatagt gtcagctgtt gatttatcaa atctatattt tcaaattcca gtttttaaag
     6001 ttagtgtgtt tcttaagagt gatgagatgg aaatgattag aaaagctatg gatcagatgc
     6061 aagtttctag ttatgtacaa tcatcaaaga ttaataaatt tgaaaacaac agctttagac
     6121 agtattttag taaagaaaat tttttaatat gtactgaatc agacaaggta aatttacttg
     6181 aaaagatggt tgagagttta tctgttggtg aatcaaatga gtttgaacaa tctttacttt
     6241 atggaattaa acagcgcgaa gaattaagtt cagttgtttt ttctgaaaaa attgcagttc
     6301 cgcatcctat tcagcccttt ggtacagagg gaaaggtttc ggttgcaatc tgtaaagatt
     6361 cgttactctg ggataatcaa agttcatatg tccagctagt atttcttcta tctccatcaa
     6421 tatatgggaa cgaaggtttg gcaactgtga ctaaaaagat agtctctctg acagagaatg
     6481 atgagttgca aaatcagcta atatcttgca ataactttga agattttatt agcatatttg
     6541 agaagataaa ataggaggtt catatgaatc aagaggaact gcaggttgca gcatttgaaa
     6601 ttatcctgca ttcgggaaat gcaaggtcag aaatacatga agcatttgca aaaatgagag
     6661 aaggtagttt tgatgatgca gaaagtaaat taaatcaatc aaatgagata attcttgaag
     6721 cgcatcatgc acaaaccaaa ctcttgcaag aatacgcaag tggagtggaa attaaaattg
     6781 aaattatcat ggtacatgct caagatcatt taatgaccac tatgacatta ttagaagtag
     6841 caaaggaaat gttagctctt tataagaaag ttaactaaat atgtgttgtt atataaggag
     6901 gaaatgatat ggataaaaaa gaacgacaaa agattgaaca acaacgtcga gagatggctc
     6961 taactaatac tttttttaat cgatatcttc ttctacgtta ttcaatagca ctcttctttt
     7021 ttgggaatat ttattggctt ttgaatcagt ttattaatcc ctcgcctatt attattttcc
     7081 ccattatgct catagtattt tctattttag caactgttga acaatttaaa ctctatggaa
     7141 ataggaaaga aaagttggga ataacactaa tgtttgttag aatacaaata cttatttcaa
     7201 taggattact tgttttaact tggacaagtt ggtttaagaa tctttttccg atttttgaaa
     7261 ataaccaagt agcacgttta tttgtttttg tagttcttct attaggttta gttctgagtt
     7321 tgttagacat tagaagaatt aaaaaaattt ataaacgaac agataaggct tatcaacaat
     7381 ttgtccaatt ggaaaagaac tcacttagtt tataatcctg atctagtata atttgtattt
     7441 gaaactagtc tttagaaagt aaaaattatt atgttttatt aaggaggtct atttatggat
     7501 caacaaaacg ggttgtttgg ttttcttgaa aaccatgtta tgggaccaat gggcaaactt
     7561 gctcagttta aagtagtgcg tgctatcacg gctgcaggta tggctgctgt accatttact
     7621 attgtaggat caatgttttt ggtattcagt attttgccac aagctttctc attttggcca
     7681 attgtggcag atattttctc tgcttcattt gataaattca catcacttta catggttgca
     7741 aactatgcga ctatgggttc tctatctctt tatttcgttc tatcacttgc atatgaattg
     7801 acaaaaattt atgcagagga agaagaactc aatatgaatc ctcttaatgg tgccttgctc
     7861 gccttgatgg cttttgtcat gacagtaccg caaatcattt ttgatggtgg aatgatgaag
     7921 actgtgacaa gtctaaaaga aggtgcagta attgcagatg gatgggcaat gggaaatgga
     7981 gtcgcacgtt ttgggacaac agggattttt accgcaatca ttatggcaat tgtgactgtt
     8041 cttatttatc gtatgtgtgt taaacataat tgggttatta aaatgcctga agctgttcca
     8101 gaaggagttt ctcgtggatt taccgctttg gttccgggat ttgttgttgc atttgttgtt
     8161 atctttatca acggtcttct tgtagcaatg ggaacagata tttttaaagt cattgcaatt
     8221 ccatttggtt ttgtatccaa tctgactaat tcgtggattg gtttaatgat tatttatcta
     8281 ttgactcaac tactttggat tgtaggtatc cacggtgcga acattgtttt tgcatttgtt
     8341 agtccaattg ctcttgctaa catggctgaa aatgctgctg gcgggcactt cgctgttgca
     8401 ggtgaatttt ctaatatgtt tgtaattgca ggtggttctg gtgcaacttt aggactatgt
     8461 ttatatattg cttttgcctc taaatctgaa cagcttaaag caataggacg agcatctgta
     8521 gttccagcct tatttaatat taatgaacca ttaatttttg gattacctat tatctataat
     8581 ccagccttgg ctataccatt tattttagca ccaatggtta ctgctactat ttattacgta
     8641 gcgaattctc taaactttat taagccaatt atcgcacagg ttccatggcc aactccagta
     8701 gggattggag ctttcttagg gacagcagat cttcgagctg tattagttgc tctagtatgt
     8761 gcatttgcag cattcttagt ctatcttcca ttcatccgtg tatatgatca aaaattggtg
     8821 aaagaagagc aaggtatcta ataagtaaaa aagtatactc gatgatagaa tccatatagt
     8881 ttaaataatg agtgttaata ttagcagtga agaggtcttt ttaagatatt cttctctgct
     8941 ttttcatatt ttttcgctat gtagggtatg aagcaaaata gaaagtagtt cgaatagttg
     9001 ataaacagga aactgctgtt atttaaaaaa aacaataaag taaagtatgt tatcgtagaa
     9061 tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt gaggtttata
     9121 aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt tttaaaagct
     9181 acatagaaac atggtataat gtatctaaag gaggtagcat atgtccttag atatagataa
     9241 agaaaagatg acaatcatgg gaatagcttt tgaaaacaga tccgttttta agagtgtttg
     9301 gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg atgttgaaaa
     9361 attacgagat gaagctcttg ctctggggat gacttaatga agcgcaactg ttatgagtct
     9421 tatgactatg ttgatccgga taatttatat accgatccgg gttcttcagt tctaagaaat
     9481 aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat gattgctagt aagagtttga
     9541 aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc acaactgcat
     9601 aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg ttaaaagata
     9661 ttttgtccac tacatttttt caattgacta ttatttgtca tagatataac agatagaaca
     9721 gatagaacat tgcattcaga ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta
     9781 tgctaccata aaaggaggaa aacaaattga aaatttttaa gggagagttt tatcgaatct
     9841 ctgtattaac agacaagcta gtaaggttag aatactctca aactggaagt tttgaggata
     9901 gaacgacaca acttatctat aatagagatt ttggccaagt ttcgttagat tatatcgaga
     9961 catcaaacgt actagatatt atgacggact attttcatct gcactttaat aaaggagaat
    10021 ttaacgccga aaatttattt atagaattaa aaggaaattt tgccgtatat ggtagtcgct
    10081 ggtattttgg tgaatctatt gaaacgttaa aaggaacagc tcggactctg gataaggcag
    10141 atggagcaat ctcgttagaa gatggaatta ttagccgaaa tggtatagcc ttattggatg
    10201 attctcaagg atttatttgg gatgaacaat ctggttatat tgagagagaa aatcaaattg
    10261 acctgtattt ctttgcctat gggcatgatt atagaggagc aatcagagac ttttaccatt
    10321 tgactggttc aacacccttg ttgccaagat atgctttagg caattggtgg agtagatatt
    10381 ggccttatac gtcggatgaa tacttggatt taatagacag atttgaaaca gagaaaattc
    10441 cattatctat cggtgtgtta gatatggatt ggcatataac tgacattcca gctcgttttg
    10501 gaagtggctg gacaggatat agttggaata gaaacttaat accaaatcca gaacagttat
    10561 tgcaacaact tcatgataga aagttaaaac tctccttaaa tgtccatcct gctgatggga
    10621 tacgggctta tgaagaagct tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac
    10681 tagaagaacc tgctattttt gattttttta atccctcttt tagggaagcc tactttaaag
    10741 atgttcatta tgagctagaa aagcagggag tagatttttg gtggattgac tggcaacaag
    10801 ggacacaagg tatgctagat ccactttggc ttttaaacca ttatcactat caggatagtt
    10861 gtaaaaatgc agaaggtggt ttgattttat caagatatgc aggtcctggt agtcaccgct
    10921 accctgttgg tttttcaggg gatactatta ttagttggaa ttccttaagg tttcaaccct
    10981 attttacagc gacagcatct aatatcggtt atagttggtg gagtcatgat atcggtggac
    11041 atatgttggg ggattatgac gaagagctac aaactagatg gctacagttt ggtgttttta
    11101 gtccgattac tcgattacat agttctagaa gtccttttaa tagtaaagaa ccttggttct
    11161 tttcagaaac aacatctaag attatgaaga aataccttcg tttgagacat cagatgattc
    11221 cctatctata taccatgaat gtaaagacac atgaggaagg tgccccatta atcagtccaa
    11281 tctattattt ctatccagag aatgatgaga gctataatgt tccaaaccaa tacttttttg
    11341 gaacagaact gatggtggct cccattgtag aaaagatgga tttgacattc caatctgcaa
    11401 aagtagatgt atggttccct gaaggtgaat ggtatgactt cttttcagag aaaaaataca
    11461 caggtggtgt gaagttaagt gtttataggg acatctcgac tacgcctgtg tttgcaaaaa
    11521 gtggtgcaat cattcccttg gttggttctg agataggtat gggtgttgat ttacctgagg
    11581 ttgtagattg gtatgtattc ccagggaaac aacatttttt tgaaatgctt gaagatcaaa
    11641 atggtcaaag atataaaaca agattatcaa tcgattggga aatgggaatg gtagagttag
    11701 cattacaagg agattctagt atcgttccaa gcaatagaaa acatagaatt cattttaaag
    11761 gaacgaatgt gtctataatt gaattgccaa ataagaatga tacagctaaa tttgaatgga
    11821 aagataataa aaggacatct ttaaatgacg aagtttttag actactaaag acagcttctc
    11881 ttccatatga attaaaagat agattgttaa atcaattcat caatgcgaaa aactctcatg
    11941 acttaatgaa tatcttgcat catcaggata aggaattgag agggcgtttg ttggaaatga
    12001 tatttactag ccaaaactaa ttgaaataat tagaaagtca tttgtttagt gtatatgaag
    12061 attctgtatg gtattcgtta tcactggtca cattgaaaat gtgaaataag cacctacaac
    12121 atagacttta caacacttca tgtttcatat catggggtgt ttttctattt aagtcaaagc
    12181 ccatcaaaaa atctcactat tcatcaggtt aaaggaaacc taatcatagt gagattgtga
    12241 attatagtag agtttgtatc gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc
    12301 gttcaaagac ttgcccatct cgaccgatga gaaacttagc gaaattccat tcgattcgtt
    12361 ttcctagtgg gccggatttc tggtctttta accagacata gagagggtct gcttccttac
    12421 cgttgacctt aatcttggca aaacgtggga aggtggtttg aaaatgtagg ctacagaagg
    12481 cgttgatttc ctctgcgctg ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca
    12541 atatttcgaa gccctgatct tgatagcgtt catagagttc ttgaagtccc tggtactggg
    12601 gcgttaaacc acatccagta gcagtgttga caatcaagag aactttgcca cgatagctat
    12661 ccaagggagt tgcttggttg ttttggttca aaacggaaaa atcataaagt gaagtcatga
    12721 gggcctcttt tctttttcta cattgtaaca gtttttactt ttttcgtcga gtcggatgga
    12781 agatattgtt gaagaataag ccttcaatat gatagaaacc gtttacaaat aactttaaaa
    12841 atggtatgat ttaattaaac cggtttactt agttgctata aatctctaat ttgagattta
    12901 gttcctattg attttacaat atgtttattg gagtgtatac atgcaaacaa aaacaaagaa
    12961 gctcattgtg agtttgtctt cacttgtttt atcaggattt ttattaaacc attatatgac
    13021 agttggagcg gaagaaacga ctacgaatac cattcagcaa agccagaagg aagttcagta
    13081 tcagcaaagg gatacaaaaa atttagttga aaatggtgat tttggtcaga cggaggacgg
    13141 aagcagtccg tggacaggaa gcaaagctca ggggtggtca gcttgggtag accagaagaa
    13201 tagtgcagat gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag
    13261 ccatgagaaa ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta
    13321 taaactgcgt ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat
    13381 tgaggaaagt gataaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga
    13441 ctggcagacc attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga
    13501 gttattctat gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt
    13561 agcagaccag ccttctgagg actatcaaac agataaacag cttgaggaaa agattgattt
    13621 accaattgga aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc
    13681 tgacgttgct tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt
    13741 cattgtcagt aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt
    13801 taaggatgca tacacagacc gtttggatga ctggaatggc atcatcgctg ggaatcaata
    13861 ctatgattct aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc
    13921 tgatagccta tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc
    13981 aaattataaa atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa
    14041 gcaagtgacc aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag
    14101 ggattccatg gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa
    14161 ctggtgggat tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa
    14221 agaatacttc tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc
    14281 agatcccgaa catttccgaa agacgactga taacccattt aaggctctag gtggaaactt
    14341 agttgatatg ggaagagtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat
    14401 ttcttctacc attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt
    14461 ttatcaagat ggatcctata tcgaccatac caatgttgcc tatacgggtg cttatgggaa
    14521 tgttttgatt gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat
    14581 cgataaagat aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct
    14641 ggtgaatgga gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga
    14701 ggggcacgtg gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga
    14761 aggagaaacc aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta
    14821 ttatgatgtc tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt
    14881 aagtgatgca ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat
    14941 ggataaaaca gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc
    15001 cagtcgtacc ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag
    15061 tgatgggatg ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc
    15121 aacagttaat ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag
    15181 cgatacaggt aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa
    15241 tgcgacagca accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg
    15301 gtttatgcta aaggataaga tcgccttttt aggaagcaat atccaaaaca cttcaacaga
    15361 tactgctgca actacaattg accagagaaa actggaatca agtaatccat ataaagtcta
    15421 tgtcaatgat aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag
    15481 tgtcttttta gaatcatccg attcgaaaaa gaatattggt tactttttct ttaagaagag
    15541 ttcaatcagt atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca
    15601 gtcagacaag gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg
    15661 agattcttat ggctatatgc tcatccctaa cgtgggtcgt gccaccttca atcaaatgat
    15721 aaaagagtta gaaagaagcc tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc
    15781 caaacaagga gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca
    15841 attccaagtt ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat
    15901 tgcctactat aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct
    15961 agagcaagca gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga
    16021 aaagaaccat tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc
    16081 aagtctaggg ttcttgctac ttggggcgtt ttatttattc cgtagaggaa agaacaacta
    16141 atttgttcat catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa
    16201 ggccaaatat cttcggattt ttcttttaaa aaaggataag ttgatactta tcctttttac
    16261 ttcattatgt gactatagcg ttttgaaact agaataggac atcataactg ctaaaagatt
    16321 tctataaatt catttgattt tcctaatcaa tttattcgta tcctatttca ctctactata
    16381 ttagtccgtc tcgcacctca cggagcgaga caaaacaacc acccgctatg cgggtgcgcg
    16441 tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca atccacttgt
    16501 aaagcgaaag gagaaaaaat atggcacaaa aggctcatag tttatctcac acaaagtgga
    16561 ggtgttctat cacattgtgt tcacccctaa gtatagacga aaagtcatct ataatcaata
    16621 tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg ttgaaatgat
    16681 cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccac taaggctaag
    16741 tgtttcgagt ttcatgggtt atttaaaagg aaaaagtgca ctcatgatgt ttgacaaaca
    16801 cgccaatctc aagtacaagt ttgggaatcg gcatttctgg gtggaaggtt attatgtaag
    16861 tccagtaggg cttaatgaag ccacaattaa gaaatatagt caagattaaa gaaattatcc
    16921 agtggatgat ttcttcacga gtatgaaaat ttgagaacta gtaaagtatg atatatagta
    16981 aaatgaaata agaacaggac aaaatcgatc aggacagtca aatcgatttt taacaatgtt
    17041 ttagaagtag aggtatacta ttccagtttc aatctactat agcactagat aaattgagtg
    17101 taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt ctcttaaaga
    17161 ggcaagtgac gagtcaagag caataaggct tgaacaacgt aaaagccagc gtctttaggc
    17221 gctggctgat gatttgggct tatagctctg ggataaacca cccgttagac gggtagttat
    17281 gattttatct gagtgtaata tactgttggg caatctcgct gatgcggtca aagttgcctt
    17341 gggaagcgag tttattgagt tcgccaccaa ttccaacggc atctgcacca gcagcgaacc
    17401 attgagggat gttgtttagg ccgactcctc cggttaccat tacggaaact tgtgggatcg
    17461 gtgccttgac tgcagagata tatgctggac tgagagtact acctgggaag agtttgatga
    17521 tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag cctggaatgt
    17581 acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat ggagaaacaa
    17641 cgtaatttgc tccagctaga atggcatctc tagcagttac ggcatcaagc acagtacctg
    17701 caccgataca aacactctga tcgtcctgat acaagtctac aagttccttg atgatttgtc
    17761 ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg atacaagcaa
    17821 tcgaggcttg tagtccttct tcctttgtat ttcctcgaat gacagcgaca attttctgtt
    17881 tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga atgatatctt
    17941 gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg tctcctggaa
    18001 gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt agggaggaat
    18061 gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca attcgttgat
    18121 agactgcagt ttttagttgg acagactctt caaatcgttc ttccagagca taggcttgat
    18181 agacattttt gtcttgctca tcactagatc ggagggtatg gaaaatggcc ttgaaaccat
    18241 aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca ctgtctcttg
    18301 gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag caatagtcag
    18361 taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc atctttgttc
    18421 tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc aagagtagga
    18481 gaaggatcgc acggacctct tgaccgatag ctatggtgat tccactaaaa tgaaaatggc
    18541 taatcccctg aaagagagaa tccatatcta gcatgtttgg ccgaatctgg ctgatactcg
    18601 tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc tccaaatagt
    18661 agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg tgctgtttca
    18721 agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag actttcgttg
    18781 agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca aaataagtcg
    18841 aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga attaatggtt
    18901 cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa tagctttact
    18961 tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt tcaaagaagt
    19021 attcttggaa gtatttgcca gagatggtgt ctttgaggaa gtcttggtcg attgttttaa
    19081 ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata cgagcgttgc
    19141 gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca gcaaataagc
    19201 gttcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg gcataaggga
    19261 tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt gggtccactg
    19321 ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct acacccgtac
    19381 cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca gccattagtc
    19441 cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca tagttaaata
    19501 attggtagtc ttttttatct gtcgcttctt ttagactatc gtaaataatg tgattcttgc
    19561 tagcttgact attttcattg attaatgcga ttttcataag atcttctttc tatttttact
    19621 caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg tggccattga
    19681 caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct tcaggatttc
    19741 cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg cgagaaccat
    19801 cttcttgcaa ctcacgaaga ggtgctgttt gaggagtggc aatataaccc ggtccaattc
    19861 cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc aacattttca
    19921 agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg ctcatcatcg
    19981 aacaaatatt gataatcttt ccatgccctt tctttatcat agaaggaata actgcctttg
    20041 aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca gcggcgctca
    20101 tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg tcaatgacac
    20161 caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct gtcacgtcac
    20221 agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct ttattgacca
    20281 gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag gatttggcaa
    20341 tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct tttaaagaaa
    20401 actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat ttgttaagac
    20461 ttctctataa ccaaattata ttctagcaaa ccggttttgt caataaataa atatttttat
    20521 ttataaaaag atttgttttc ctgaaaaacg gaatgttttg aaatttctgt ttattaaaat
    20581 ggttaaaaag ataatgaaag cgctaatatt tttttaaaaa aactattgac aagataaaaa
    20641 taaaggatta caatggggaa tataaagtaa accggtaaac ctaaacaaga aaggagaaaa
    20701 gatgaaaatt gtacttgtag ggcatggaca ttttgctaca gggatttata gttctttaca
    20761 attgattgca ggtaatcaag aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc
    20821 agatgaactc aagcaaaaaa tcttacttgc aatttcaaat gaagaagaag ttttaatcct
    20881 aagtgatctc ttgggaggat cgccattcaa ggtttcttct accataatgg gagaaaatcc
    20941 agtcaaaaca atgaatgttc tctcgggttt gaacttagcc atgttaatgg aagcagtctt
    21001 tgctagaatg gctcatagct ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg
    21061 cggagtcgta aatggtaaag aattgttttc aacggatgca gaggaagaag atttcgaatc
    21121 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
    21181 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
    21241 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gacgccagct
    21301 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
    21361 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
    21421 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
    21481 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
    21541 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
    21601 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
    21661 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
    21721 tacgatattg cagaaagtca tttctatgct tcagctaata atgtaatccg tgatgacgct
    21781 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
    21841 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
    21901 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
    21961 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
    22021 aatgatggta gtgctcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
    22081 catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct
    22141 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    22201 gggacaagtc ttctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    22261 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    22321 ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga
    22381 acggttgatt catggacaag gacaactttg ggtaaaatac ctagcttgta atacggtcat
    22441 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    22501 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    22561 ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt
    22621 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgcccctgg
    22681 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcag ccctcaagga
    22741 attaagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    22801 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    22861 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    22921 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    22981 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    23041 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    23101 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    23161 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    23221 acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagtttac tctaaatgca
    23281 acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg
    23341 gataccttgt tgaaactcgt agactacatt ccaccggtat tacttacagg tttgacagtt
    23401 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    23461 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    23521 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    23581 acagcgaatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    23641 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    23701 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    23761 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    23821 cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc
    23881 ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga
    23941 ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    24001 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    24061 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    24121 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    24181 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    24241 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    24301 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    24361 gacaacatat aaactcgtta ttttaacagt tgtcatcgga attatcggaa gctggcttaa
    24421 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    24481 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagacg
    24541 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    24601 ggaattcatg gaaaaatcat ttctatcaaa gatgacttgg tctccttgca gattgcaaaa
    24661 ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    24721 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    24781 gtcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    24841 gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat
    24901 atggagcctt gttcaaaaat ccatcaaatc cagccgatgg tatgggatca agtatttgaa
    24961 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    25021 gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat
    25081 tggattgagc aggtgagaga attttctcct caatccttga tgactagaac cttggatacg
    25141 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacatgcta
    25201 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    25261 agctactatc gcgccaagta cacccttagt aactggggga ttttacaaac aattccgatg
    25321 cttgctatct attatttctt ttcagataag atggacctag aagaagctta ccattttgct
    25381 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    25441 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    25501 ccagacttgc aagatagtta ccgagagttg ctggaaaaga tggcgaccta tattcaaatg
    25561 atgacaggct tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca
    25621 gaaattttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    25681 gttaaagtcg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    25741 gaatttgaaa agagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc
    25801 tgcattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat
    25861 agccatagtg acgagaatag tttttgctta cagtatcaag gacaacctat tttcatagat
    25921 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    25981 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    26041 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    26101 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag aaaaatcctc
    26161 atgttggtag aggatgtctg gctcttggtg gatgacatca ggtgtcaagg tcagcatgag
    26221 gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    26281 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    26341 aatgagcttg aaagaagtaa caaactcacc aagcgccaat tctttgagaa tcagatgctg
    26401 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    26461 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    26521 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    26581 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    26641 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    26701 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    26761 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    26821 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    26881 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    26941 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    27001 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    27061 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    27121 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    27181 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    27241 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    27301 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    27361 ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg
    27421 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    27481 ccgttatcaa agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata
    27541 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    27601 aaggacaaca ggctacaaag attttgattg atcagattga aggccgtaat caagaagaaa
    27661 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    27721 aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    27781 ttatttgctt atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    27841 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    27901 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    27961 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    28021 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc
    28081 tcctgaaata agggcgaaga aaaggaaaat actgataaaa acatgaatgt tcagtagtct
    28141 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    28201 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata gttttaaaaa
    28261 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    28321 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    28381 aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc ttgatttttc
    28441 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa
    28501 ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    28561 tcatctatga gtatactgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    28621 cctgctttca gacctgggta gtgtagttgc ttgctttctt tctcattcag catatctggt
    28681 tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccagc agcgatgagg
    28741 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggct
    28801 agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    28861 ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    28921 gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa
    28981 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    29041 cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt ctgtctcgag
    29101 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    29161 acacgattca tctggtctcc tttctgattt atgtcgtata tatttgacta tattatagtc
    29221 ttttaaacat aaagtgtcaa gtatatttga catatttttt gaagaaatag tagtctcctt
    29281 gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga taagatatga
    29341 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa
    29401 aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    29461 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    29521 acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc tttatcaagg
    29581 ataacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa
    29641 tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagcgt ggtttttctt
    29701 ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg
    29761 aagtggttaa tcactatgac tatcatgatt tggttcgtat tttcttcaaa tacggtgagg
    29821 ataaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg
    29881 agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga
    29941 agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    30001 tgggagcggc agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa
    30061 tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag
    30121 cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga
    30181 tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc
    30241 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat
    30301 ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    30361 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    30421 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    30481 gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    30541 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    30601 tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa
    30661 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    30721 ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt
    30781 tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc
    30841 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta
    30901 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    30961 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga
    31021 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggagcaaa
    31081 gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg aagctgcaga
    31141 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    31201 ttctagtttt atcggcctag ctcagctcca tgaaaatgaa gatggaagca agagcttgct
    31261 gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat
    31321 tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag tttcccaacg
    31381 aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga
    31441 aacccagatg gattcttttc aagagaaggt aaaaggaaag tacatgacag cgactttggt
    31501 cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg atgcagatac
    31561 aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa gtaactatga
    31621 gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata atacctttcc
    31681 aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga ttcgagattg
    31741 ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag gttttgcaca
    31801 ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta cctggcttga
    31861 ttatcttaat cgttttaagt ttggagttcc gacccgtttc ggtttgacgg atgagtatgc
    31921 tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg gacaagggat
    31981 ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat
    32041 gctggagcct aaatttatta gtgccgttta tgatccaaat gatcaaactg ctcggaaatc
    32101 tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa
    32161 catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa
    32221 gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc
    32281 tgacgagaaa aatggtggtt atctagtcgg gttaaccgac tatattttct cggctgtatc
    32341 gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    32401 ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat
    32461 gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa gtcaacaaag
    32521 tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg
    32581 tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc
    32641 tgaagaaggg aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagtaga
    32701 ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct
    32761 caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc
    32821 taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    32881 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    32941 tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc
    33001 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt acttctgttt
    33061 tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatatg ggaatgattt
    33121 tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc
    33181 gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag
    33241 ttatcttcta tcttttctat gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag
    33301 tgcatctagg gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg
    33361 cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt
    33421 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg
    33481 ccatgattgg tggtttgctc agttttttca tctttaacca taagcctgct aaggtcttta
    33541 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    33601 accaagaatg gactctcttg attatcggaa ttgtatatgt ttttgaaaca acttctgtta
    33661 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    33721 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    33781 aggttgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc cttgcaattt
    33841 tgtatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    33901 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg
    33961 aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg
    34021 aacgatttat cctgttctta tttcatttta ctatacagtt ttgagatggt tgatagaact
    34081 gacgaagtca gctcaaaaca ctgttttgag gttgtagaca aggcgaagct gatgtggttt
    34141 gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct
    34201 tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt
    34261 atttaaagta aaatagaaag aggtgagtct atgtttcatc tagcaatctt cagaggtaaa
    34321 gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt agcgatctag
    34381 ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat cataactaag
    34441 taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata acatggatga
    34501 tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc gccgttactt
    34561 aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga ctggtcaatt
    34621 accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta tgaaacaaga
    34681 cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga
    34741 tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct cacgccgcac
    34801 caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag ttgtcgaagg
    34861 tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca aggaaattat
    34921 ttccattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa
    34981 tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct tctttgatga
    35041 aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta aaggacttgc
    35101 ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg caacaactca
    35161 agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt
    35221 gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca ttcgtgacct
    35281 ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag cggtggatta
    35341 ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc ttgtcgatgt
    35401 aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga
    35461 aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc
    35521 tctaaactat aaaacacgca ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga
    35581 tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat
    35641 cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg ctcatcgctt
    35701 gcaagaaaag gtgattggtc aagataaggc cgtagaagtt gtagctcgtg ctatccgtcg
    35761 taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct ttgtagggtc
    35821 tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt ttggaaccca
    35881 ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg tttctaagct
    35941 aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct taacagaacg
    36001 tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg ctgatcctca
    36061 agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa
    36121 tacagtaaac ttcaagaata ctgtcgttat tgcgacctca aatgctggat ttggctatga
    36181 agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga aacccttctt
    36241 ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact tgactaagga
    36301 agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct tggctaagaa
    36361 agacattgac ttggtagtta gtcaagcggc taaagattat atcacagaag aaggttacga
    36421 cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc gtgataaggt
    36481 gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata tggaagatgg
    36541 cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa agaaggagcc
    36601 agctgaaaaa aactggttcc tttttaggta cgacaggcat gtcgtatagt agaagtgtat
    36661 tattccagtt tcaatatact atagtagctc agaagtcggt acttaaacgt gctatatcaa
    36721 aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaacgacatg
    36781 cgttaaaagt tagttgaacc gccgtatgcc gaacggtacg tacggtggtg tgagaggggc
    36841 tagagattat cccctactcg attgtctata gctatagggg taaagttatt agagaggttg
    36901 ctagtttata gagacatctt gatttgtaaa aagttaaatt ttagacaatt atccccttta
    36961 aaaaatctat taaaccatag ctagttgaag taaattttta tagaacataa ttttatttat
    37021 caagacattg tagagttgag gcaaattgaa aaagaaagtt taaaagttga taataagtca
    37081 ataagaaagc tattaattct aacgagatta tttgatagta atttgttttt tcagctacta
    37141 ttcggacaat gttattataa taaacacagg agagaacacc agaaggtagg gacatcagaa
    37201 gaaatagttc aggatatagt taacataatc atcaaagaag ctcctagact cgctaatgtt
    37261 aatttggaaa catattatcc agatgaatat atgtcaaata cattgaagca attactactt
    37321 tttagagagg agttcataaa aaatattttg aatgggattg atgtggatga aacagtagta
    37381 atagaaaatg attttgtaga agagttggag aactttttaa aagagaatga tttgctagat
    37441 ttttcaaata gcatattttt tcagttatct ggagataaag taatagtgaa taatatttat
    37501 ccaggatatt tagcatattt taataggttc cttacatttt atccgaaaat attcgctatt
    37561 aaagaagttg gagaatatat tgacttttta aattttgaaa agagaattgc ggatatgttt
    37621 tattgttggg gatttaatgc aaattctaga gtgttgacag ctgaaaaaat aattgaaatc
    37681 ccaaatcacc aaatcaatgc taagtacata aaaaaagtta taaaaatgag tgaactcttg
    37741 tttggtgttg atagtaataa cagaattcgg ttgcttaaca atagaaggga attgataaaa
    37801 actattttcc aaggttctgt aattaagtca gcaattcctg ctctagctgc tactttggat
    37861 acaatcagta acagtggatc atttcaaatt tctttatcaa agcagataat taataattta
    37921 gtattaagtg gtaaagataa agttacaatt cctaggatag agttagataa tgttgttctt
    37981 tcaagacaga agattattgt atcagtttcg tatataaatg attttttgga tttgagattt
    38041 ccagataaaa tagaatacat tttaaatttt ttagaaggat ctggtttcaa tactaaagta
    38101 atggtctact ttgggaaaat tgtagaagaa gataagaact attttgttaa tcttgaaaaa
    38161 cctcagtatt ttgattttac cagtatactt ttcaataagt tattctttaa agaattaaac
    38221 aagtttgatt acatggttat tgaagaactc attccaaatc ttgatgaaga tgtaatgatg
    38281 acagagtata taaaagagta tactgaatag gagcaatcta ttatgatttt aagtaaagta
    38341 cgttgttaca tatataattc taaaattaga ggtaaagttc tgtatgaatt atatgaattt
    38401 ataaatgaaa ataagcaatt gatggacgca attaattcaa ttaaagttga cagtagtaat
    38461 ggttttagta ttcaaatatt acatttagga gaacagcaaa caactgtctt attaacagat
    38521 ttttttacta aaactttaga cttgtttaag gaatttaggg ttacaaataa gagtactctt
    38581 gagcaggtga aaaatcaaat tagcatacta aattcttctg gtccaaaaat ggatttaac
//
LOCUS       DAVBED010000014        37452 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBED010000014 DAVBED010000000
VERSION     DAVBED010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.014"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQ547_000731"
     CDS             complement(<1..777)
                     /locus_tag="VQ547_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2542611.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQ547_000732"
     CDS             complement(873..2183)
                     /locus_tag="VQ547_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2542612.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQ547_000733"
     CDS             complement(2310..3305)
                     /locus_tag="VQ547_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2542613.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQ547_000734"
     CDS             complement(3667..5148)
                     /locus_tag="VQ547_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2542614.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQ547_000735"
     CDS             5591..5755
                     /locus_tag="VQ547_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2542615.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQ547_000736"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQ547_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2542616.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQ547_000737"
     CDS             6417..6587
                     /locus_tag="VQ547_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2542617.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQ547_000738"
     CDS             6626..7234
                     /locus_tag="VQ547_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2542618.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQ547_000739"
     CDS             7265..7468
                     /locus_tag="VQ547_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2542619.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQ547_000740"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQ547_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQ547_000741"
     CDS             8054..8341
                     /locus_tag="VQ547_000741"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2542620.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQ547_000742"
     CDS             complement(8619..9389)
                     /locus_tag="VQ547_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2542621.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQ547_000743"
     CDS             complement(9404..10252)
                     /locus_tag="VQ547_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2542622.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQ547_000744"
     CDS             complement(10249..11724)
                     /locus_tag="VQ547_000744"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2542623.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQ547_000745"
     CDS             complement(12047..13402)
                     /locus_tag="VQ547_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2542624.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQ547_000746"
     CDS             complement(13412..13729)
                     /locus_tag="VQ547_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2542625.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQ547_000747"
     CDS             complement(13746..14063)
                     /locus_tag="VQ547_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2542626.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQ547_000748"
     CDS             complement(14076..15761)
                     /locus_tag="VQ547_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2542627.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQ547_000749"
     CDS             complement(15766..16662)
                     /locus_tag="VQ547_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2542628.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQ547_000750"
     CDS             complement(16665..17927)
                     /locus_tag="VQ547_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2542629.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQ547_000751"
     CDS             18207..19385
                     /locus_tag="VQ547_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2542630.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQ547_000752"
     CDS             complement(19613..20059)
                     /locus_tag="VQ547_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542631.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQ547_000753"
     CDS             20129..20788
                     /locus_tag="VQ547_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2542632.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQ547_000754"
     CDS             complement(20840..21991)
                     /locus_tag="VQ547_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2542633.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQ547_000755"
     CDS             complement(22006..22737)
                     /locus_tag="VQ547_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542634.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQ547_000756"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQ547_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQ547_000757"
     CDS             complement(23039..23815)
                     /locus_tag="VQ547_000757"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2542635.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ547_000758"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ547_000758"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2542636.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQ547_000759"
     CDS             complement(25009..25608)
                     /locus_tag="VQ547_000759"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2542637.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ547_000760"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ547_000760"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2542638.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ547_000761"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ547_000761"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2542639.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQ547_000762"
     CDS             complement(27374..27940)
                     /locus_tag="VQ547_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2542640.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ547_000763"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ547_000763"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2542641.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQ547_000764"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQ547_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQ547_000765"
     CDS             complement(30481..31482)
                     /locus_tag="VQ547_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2542642.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQ547_000766"
     CDS             complement(31590..31958)
                     /locus_tag="VQ547_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542643.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQ547_000767"
     CDS             complement(32054..32764)
                     /locus_tag="VQ547_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2542644.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQ547_000768"
     CDS             complement(32767..34458)
                     /locus_tag="VQ547_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2542645.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQ547_000769"
     CDS             complement(34470..35480)
                     /locus_tag="VQ547_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542646.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQ547_000770"
     CDS             complement(35583..36650)
                     /locus_tag="VQ547_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2542647.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQ547_000771"
     CDS             complement(36675..37334)
                     /locus_tag="VQ547_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2542648.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVBED010000015        37217 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBED010000015 DAVBED010000000
VERSION     DAVBED010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.015"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            175..1938
                     /gene="aspS"
                     /locus_tag="VQ547_000772"
     CDS             175..1938
                     /gene="aspS"
                     /locus_tag="VQ547_000772"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2542649.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1916..2857
                     /locus_tag="VQ547_000773"
     CDS             1916..2857
                     /locus_tag="VQ547_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2542650.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2977..3057)
                     /locus_tag="VQ547_000774"
                     /pseudo
     CDS             complement(2977..3057)
                     /locus_tag="VQ547_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3193..4179)
                     /locus_tag="VQ547_000775"
     CDS             complement(3193..4179)
                     /locus_tag="VQ547_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2542651.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4189..4989)
                     /locus_tag="VQ547_000776"
     CDS             complement(4189..4989)
                     /locus_tag="VQ547_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2542652.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5250..6092)
                     /locus_tag="VQ547_000777"
     CDS             complement(5250..6092)
                     /locus_tag="VQ547_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2542653.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6094..7386)
                     /locus_tag="VQ547_000778"
     CDS             complement(6094..7386)
                     /locus_tag="VQ547_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2542654.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7497..8768)
                     /locus_tag="VQ547_000779"
     CDS             complement(7497..8768)
                     /locus_tag="VQ547_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2542655.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9318..10835
                     /gene="malQ"
                     /locus_tag="VQ547_000780"
     CDS             9318..10835
                     /gene="malQ"
                     /locus_tag="VQ547_000780"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2542656.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10861..13119
                     /locus_tag="VQ547_000781"
     CDS             10861..13119
                     /locus_tag="VQ547_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2542657.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14163..14735)
                     /locus_tag="VQ547_000782"
     CDS             complement(14163..14735)
                     /locus_tag="VQ547_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542658.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15357..16205)
                     /locus_tag="VQ547_000783"
     CDS             complement(15357..16205)
                     /locus_tag="VQ547_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2542659.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16350..16628
                     /locus_tag="VQ547_000784"
     CDS             16350..16628
                     /locus_tag="VQ547_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542660.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16630..18693
                     /locus_tag="VQ547_000785"
     CDS             16630..18693
                     /locus_tag="VQ547_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2542661.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18771..20027)
                     /locus_tag="VQ547_000786"
     CDS             complement(18771..20027)
                     /locus_tag="VQ547_000786"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2542662.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20169..22634
                     /locus_tag="VQ547_000787"
     CDS             20169..22634
                     /locus_tag="VQ547_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2542663.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22699..23610
                     /locus_tag="VQ547_000788"
     CDS             22699..23610
                     /locus_tag="VQ547_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2542664.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23840..24538
                     /gene="dapD"
                     /locus_tag="VQ547_000789"
     CDS             23840..24538
                     /gene="dapD"
                     /locus_tag="VQ547_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2542665.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24606..25736
                     /locus_tag="VQ547_000790"
     CDS             24606..25736
                     /locus_tag="VQ547_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2542666.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25748..26287
                     /locus_tag="VQ547_000791"
     CDS             25748..26287
                     /locus_tag="VQ547_000791"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2542667.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26271..26948
                     /locus_tag="VQ547_000792"
     CDS             26271..26948
                     /locus_tag="VQ547_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2542668.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27020..27919)
                     /gene="galU"
                     /locus_tag="VQ547_000793"
     CDS             complement(27020..27919)
                     /gene="galU"
                     /locus_tag="VQ547_000793"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2542669.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27941..28957)
                     /locus_tag="VQ547_000794"
     CDS             complement(27941..28957)
                     /locus_tag="VQ547_000794"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2542670.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29169..29546
                     /locus_tag="VQ547_000795"
                     /pseudo
     CDS             29169..29546
                     /locus_tag="VQ547_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29726..30151)
                     /locus_tag="VQ547_000796"
     CDS             complement(29726..30151)
                     /locus_tag="VQ547_000796"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2542671.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30219..30869)
                     /gene="phoU"
                     /locus_tag="VQ547_000797"
     CDS             complement(30219..30869)
                     /gene="phoU"
                     /locus_tag="VQ547_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2542672.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30884..31636)
                     /gene="pstB"
                     /locus_tag="VQ547_000798"
     CDS             complement(30884..31636)
                     /gene="pstB"
                     /locus_tag="VQ547_000798"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2542673.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31638..32453)
                     /gene="pstA"
                     /locus_tag="VQ547_000799"
     CDS             complement(31638..32453)
                     /gene="pstA"
                     /locus_tag="VQ547_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2542674.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32446..33309)
                     /gene="pstC"
                     /locus_tag="VQ547_000800"
     CDS             complement(32446..33309)
                     /gene="pstC"
                     /locus_tag="VQ547_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2542675.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33427..34302)
                     /locus_tag="VQ547_000801"
     CDS             complement(33427..34302)
                     /locus_tag="VQ547_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2542676.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34469..35800)
                     /locus_tag="VQ547_000802"
     CDS             complement(34469..35800)
                     /locus_tag="VQ547_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2542677.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35801..36508)
                     /locus_tag="VQ547_000803"
     CDS             complement(35801..36508)
                     /locus_tag="VQ547_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542678.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36592..37077)
                     /locus_tag="VQ547_000804"
     CDS             complement(36592..37077)
                     /locus_tag="VQ547_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2542679.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            37063..37217
                     /locus_tag="VQ547_000805"
                     /pseudo
     CDS             37063..37217
                     /locus_tag="VQ547_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10909 a         7060 c         8024 g        11224 t
ORIGIN      
        1 atacctacgg taaggcgacg ctgacgtggt ttgaagagat tttcgaagag tattagcgct
       61 aatttttagg gctttcacct gacttttaaa gactggcaaa cttttctgat gattttcatg
      121 aagagcctgc gcttttatgg taaaatagta acagaataaa agaggagaga aataatgaaa
      181 cgtagtatgt atgctggtcg tgttcgtgag gaacacatcg gacaagaaat aaccttgaaa
      241 ggatgggttg gccgtcgtcg tgaccttggt ggtttgatct ttatcgatct tcgtgaccgt
      301 gaaggaatca tgcagttggt tatcaaccct gaaaaagtat ctgcagaggt tatggcaaca
      361 gctgaaagcc ttcgtagcga atttgttatt gaggtgactg gtcaggtcgc tgcgcgtgag
      421 caagccaatg ataagttgcc aactggtgcg gttgagttaa acgtgacagc tcttattgtg
      481 cttaacacag ctaagacaac accatttgag attaaggatg gcattgaggc aaatgacgat
      541 acacgtttgc gttaccgtta ccttgacctt cgtcgtccag aaatgttgga aaatcttaaa
      601 cttcgtgcca aggtgaccca ctctatccgc aactatttgg atgagttgga gtttatcgac
      661 gtggagacac cattcctttc taagtcaacg cctgaagggg cgcgtgatta tttagtgccg
      721 tctcgtgtta ataaggggca tttttacgct cttcctcaaa gtccacaaat cacgaaacag
      781 ctcttgatga atgctggttt tgaccgttac taccaaatcg ttaaatgttt ccgtgacgag
      841 gacttgcgtg gagaccgcca gcctgaattt actcaggtcg acttggaaac gtccttcctt
      901 actgagaaag aaatccaaga tattacagaa ggcttgatcg cgcgcgtgat gaaggaaaca
      961 aaaggcatcg aagtaacgct accgttccct cgtatgaaat acgatgatgc tatggctctt
     1021 tacggttctg acaagccaga tactcgtttt gacatgttgc ttcaggactt gacagaagtg
     1081 gtcaaaggtg tagactttaa agtcttttca gaagcacctg ctgtaaaagc gattgtggtc
     1141 aaaggagctg cggacaacta ttcacgtaaa gacatcgaca agatgacgga agtagccaaa
     1201 cagtatggtg ccaaaggtct tgcttgggtc aaggtggttg atggagaatt aaacggacca
     1261 gttgccaagt tcttgactgg tatccaagaa gaattgacaa cagcgcttgc tcttgaagat
     1321 aaggacttgg ttctctttgt ggcggatacg cttgaagtgg ttaatgcaac actgggtacc
     1381 cttcgtggac gtattgctaa agagcttggc ttgattgata atgataagtt caacttcctt
     1441 tgggtggttg actggccgat gtttgaatgg tctgaagaag aaggccgcta catgagcgcc
     1501 caccatccat tcacacttcc acaggaagag actgctcacg aattagaagg tgatttggct
     1561 aaggttcgtg ccattgctta cgatatcgtc ttgaacggtt atgagcttgg tggtggtagc
     1621 cttcgtatca accaaaaaga ccttcaagaa cgcatgttca aggctcttgg tttctcaact
     1681 gaagaagcca atgaccagtt tggtttcctt cttgaagcca tggactatgg tttcccaccg
     1741 cacggtggtt tggctatcgg gcttgaccgt tttgtcatgt tgcttgctgg agaagaaaat
     1801 atccgtgaag tcattgcctt tcctaagaac aacaaggcaa ctgacccaat gacacaagct
     1861 ccatcaacag tcgctctcaa acaactagag gaactcagct tacaagtaga agaagatgaa
     1921 acaaacaaaa cgaattaagc ggtggcgcta ttatctgcgc cgctttgctt atcagataaa
     1981 aattttacgt gtcttacaaa gtatctctcg agaaaagtat gatgagaaga tttcggcctc
     2041 tctggtctat ggttttttat cagcagtagc agttaatttc tttttccaac cagggcatgt
     2101 gtattcgagt ggtgcaacag gtctggcaca gattatctct gccttgagta atcactggtt
     2161 tggttttcat attccgattt cgctaagctt ctacgccatt aacttccctt tgatggtctt
     2221 agcttggtat cagattggcc ataagttcac cgtctttacc tttatcacgg tatctatgag
     2281 ttccttcttt atccagtttg tccctgtggc aaccttgacg gaggatccca ttatcaattc
     2341 cctttttggg ggtgttgtta tgggtttggg gattggtttt gctcttcgaa acaatatctc
     2401 cagtggtggg acggatatcg tcagcctgac tattcgtaag aaaacgggta agaatgtcgg
     2461 tagtatttct ttcttggtaa atggaactat catgctgata gcaggtttga cctttggttg
     2521 gaaatacgct ctttattcta tgattaccat ctttgtctct agccgtgtga cagacgcagt
     2581 ctttactaag caaaagcgta tgcaggccat gattgtgaca aatcatccag agaaggtaat
     2641 tgaaaaaatc cataaaaaat tgcaccgcgg agcaaccatg atccacgatg cagaaggaac
     2701 ctataatcac gagagaaagg cagttttaat cactgtcatt acacgtgcag agtttaatga
     2761 atttaaacag attatgacac aagtggatcc aagctccttt gtctctgtct cggaaaatgt
     2821 tcatattcta ggaagatttg ttgagataga taattagtga ttaatactct tcgaaaatct
     2881 cttcaaacca cgtcagcttc accttgccgt atatatgtta ctgacttcgt cagttctatc
     2941 tgcaacctca aaaccatgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc
     3001 atgttttgag caacctgcgg ctagcttcct agtttgcact ttgattttca ttgagtataa
     3061 aaagatcttg ggaaaagact caatttcagt agaaaaggaa gtaaatcttc ccacattaaa
     3121 acgcatagta tcaagttttt tcaatacctg atagtatgcg tttttgcttt taacgacttt
     3181 ttgcccagtc tcttattttt cgataatttt gtgggcgatc aattgacggt aacaaatttg
     3241 tttattgttt ttattatcat taataatctg gagaatagtt tcaagggaaa cacgaccaag
     3301 ctctaaacta ttgatatcga cataggctgc caagttgagc ttgggattaa ccgagtcaaa
     3361 gctgagaaca gggacatcca gctggtgttt ggcaatatag ttacaaacgc cttcagctag
     3421 gaggctatcg gttgtgatga tagcatcaat ttgtggatcg tgcttgaata atcgcttgct
     3481 aaatttatag cccttttctt ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt
     3541 ggtaagtttg taatgtttaa gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa
     3601 gagcttttta cttcctccga taaaggcaat gcgtttgcag ccttttttga tgaaatattc
     3661 agtcgcatca aaaccagctt gaacattgtc gttgtcgaca agtgggatga aaggagatag
     3721 agatttacct aagataagga aggggaactg ttcttctgcg acgagtttta cgagagggtc
     3781 ttcttcttgg gcatagagaa agattagccc atctacacgc ttgccgtaga ccatttgtga
     3841 aatagcgttg agacgctcct tctcatcttt ccctgttgct atctgaatgg catagtggtt
     3901 ttcagatgcg acttgagaga tgccacgtag aaccgatgga aagaaaggat tctggtagaa
     3961 ggcgtctgag tcatcaggaa gaactaatcc gataacctga gtatagctgc ttaccaagct
     4021 acgagcgttg aggtttgggt ggtagttgag ttccttcata gctttgcgaa cgcgtttttt
     4081 tgtttcgtcg ctaatggttg atttattttg aataacacgg gttacggttg aaggcgaaac
     4141 accagcagcc ttggccacgt ctttaatcgt aacgggcata aaaatctcct atttatggta
     4201 atttggatca cggaaatgtg ttttataaaa gatagtgacc agatacagaa caaaaagaat
     4261 attttgtaca gtaatcaggg ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat
     4321 cagagtcggc aatcctaaac agttcaagat aaagtgatag cactctttaa aggttctaaa
     4381 tgaaaagagg cgtgatttct tagtgatata aaggagaaga ctagctccta gagagacgat
     4441 aaagaaattc aaaccaaaga ggaagctcgc accgagaact aggaagaggc tgatatagat
     4501 acgattttgt tggtaccagt ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa
     4561 actctcagtc tgaatggctc ggtaagagat gcgggtcagt tccttgcttt ccttgctgat
     4621 gactagttca tttgtatcga aatgcagttg caagtcctta ggtaattcct tgatttgact
     4681 tggaccaatc acaacagaag gggcttgact agctgttcca gtataagtta atgtgccatc
     4741 gacaattgta gcatgttcag agagatcctg gacaacctca tttgtcagag gttcatagac
     4801 attatcgata aaagtttcta gcggataggt ctcctgggag ctgttttgga tagcaatggg
     4861 taccatagac aagctgataa ggaagatact ggtaaagaga agttgaaacc agttgagctc
     4921 gaaacgtttg gacaggggct tacgaaaccc ccaaatactt gaaaaatagg aaaatggata
     4981 tggaagcata ggtatctttc taaaaggtgt tttctatatg agtattatta tatagagaaa
     5041 tgcgctttat ttcaagtcta ggagaaaaat tgcttgctac aaggatatta tttacagtga
     5101 caattgctaa taatcaatga aaatcaaagt gcaaaccagg aagctagctg caggttgctc
     5161 aaagcacaac tttgaggttg gagataaagc tgacgtggtt tgaagagatt ttcgaagagt
     5221 ataaaatgaa aaagggtggc ggggataaat tatcccttgt cgccaccact tgtaagtcct
     5281 gaaacaaagt tcttttgtag aaagaagaag agaatacaga ttggaagggc gatgaggata
     5341 gcacctgctg agaagtaggc aatcttcaag tttttcgcat tgttaacgaa ggtttggaga
     5401 cctacggcaa cagtaaagta ttctttctca cgaagcaaga aactagagag gatgtagtcc
     5461 ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa ccattgggcg aacaagtggt
     5521 agaacaattt gccagaagcg gcggaagtgt cctgcaccgt ctagttttgc agattcgtct
     5581 aaagacattg gcactgtatc gaagtagcct ttcatgagcc aagcattcat cgggatacca
     5641 ccaccaacgt agaggaagat gaggaaccag ttgtggttaa gggcgttcaa cataagcgcc
     5701 ataacgaaga aggctgtcaa agcggccata gttggcacca tttggatgat caagaagaag
     5761 accaaacttt gtttacgagc caagaagttg taacggctgt aagcataacc agcaagtacg
     5821 atgatacttg tttgaacagc catggtaatt aaggcgataa tcaaagtgtt gaggtaccaa
     5881 gtaccgtaca aggtttcagt gaagaggcct ttaaagttat caaaattgag gtcgatatta
     5941 gtatctagtt taaaggctga gacgttacct gctttaaagg ctgacataat ggtaatcaac
     6001 agtggataga taattacaat tgatagacca atcaggtaaa ggtaagtaag gctttgagtc
     6061 agtctacgtt tgagtttaat tgagttattc atcttagacg tcctccatat caaatgcgtg
     6121 tagtttcttg aatgcgatca tagagattga gatgacaatg atagagataa tcaaggtaac
     6181 agctgccgcc attgagtatt gaggagatgt acctgttgtc aaacggtaga tccatgagat
     6241 caagatatcg gttgaaccag ctccacctcc gacactacca ggtcctccac cattgaagag
     6301 gtacatgata gagaagttgt taaagttgaa ggtgtattgg ctaatcaaag taggtgccgc
     6361 aacagccaaa atcattggga aagtgatgtt gcggaatttt tgccaagcgt tggcaccgtc
     6421 aatataagct gcttcgtaaa ggtcgttagg aatagattgc aagataccca aagtcaaaac
     6481 gtagatgtat gggaatccga gccaaccttg catcataatc aaggcaatct tagtccaagt
     6541 tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa ggaaggaatt tagccaagat
     6601 tggcaatact tgagtgttga tagcaccgac actatcgtta aacatgtttg agaatgtcaa
     6661 gatagtgatg aaggctggga cagcccaagg aagaaggaaa ataacaccaa agatacgttt
     6721 tcctttgata aatggttggt tggcaatgat agctgtgaag ataccaatta cgatttgtaa
     6781 agtagaagct gccaaagccc aaatgatagt ccaagaaaga acagaaccaa aggcagaacg
     6841 gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa ccaacccagt ccaacaactt
     6901 gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg atcatcaagg ttacgataac
     6961 tgggaagata atcgcgaagg tcatggcaac ataagatgga atgatcaaga ggtaagggaa
     7021 gccattttca taaatccctt tgatcatgtc tttgagtgtg cgtggaactg gaattccatt
     7081 gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt gagaaataaa agagtacata
     7141 aacgattaca aagattagat ggaaggcacc acgaatcagc ataaagaggg aattatcacg
     7201 acctggtttg ttaccaagag tgatgaggtt gctcaattca ggggttgcaa gtgctaggaa
     7261 gtaaaggaca aatacgatgg ttacaccaag gaagataaaa cctttggctt tttgtttatt
     7321 gtaaatctgt cctaacccag gaatgataga cagcagggct gctttactag gttgttgctt
     7381 ttccatatta actcctttca taggatacta cttttttata agaaagctaa attatttgtg
     7441 tctctattga taaattcaaa gggggatttg atttccaccc cccttgaaca aattttttat
     7501 tcaccaaatt tttgtttgat tgtttctttg atcaatgtta cagcatcgtt agcagctgtt
     7561 ttagcatctt tttgaccact tacagcatca aagagcatat ttttcgctgg atcccaaact
     7621 gcagacattt gagagatgtt tggcagtggt tgagtgttct tgaactgttt gataacagct
     7681 gttgtcaact catcgttttt accttcagcg tatgaacgag cctcagtatt agctgggatt
     7741 tcgttagtct tatcatataa tactttttgt tgttcagttg caacaaggaa gtctacaaat
     7801 ttttgagaag cttcaaggtt cttaacggct tgaggaatga cccaagcttt accaccaccg
     7861 aatgcagcat attcttttcc atttggaaga gttgggatag ttgcaactcc gtagtttact
     7921 ttagcatctt taaaggcttg agctttccaa ggtccgtcga tgatagcagc tgttttacct
     7981 tcttggaatt gagtttggat taagtttcca gcaccttctg tatcttgcat acctttaggc
     8041 catttttcgt accaagattt agcgtaattg atacctacga tagaaccgtc gtttgcaaga
     8101 ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt aagcaccgtt accggcaaga
     8161 agtccatatg tatagtagaa gtttgtccag tcagctagga aggcagtagt tttaccatct
     8221 tcaccagcga atgcgtattt gctatcttta gcaaggtttt ccaagtcagc aaatgttttt
     8281 ggagcatctt tcaccaagtc tttgttgtag tacataacaa gtgactcgat aacggcagga
     8341 gcaccgtaaa ctttaccatt agcagctgtt acaagagatt tagttgtgtc gtctgtttta
     8401 gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag aaccaaggct acctacacgg
     8461 tcgtatggag ccatcataac atcagggaca ttaccagatt ggttgtcaag agaaagttta
     8521 tcaagacctc ctagagcatc accagtttta agagtgactt ttactccagc ttctttttca
     8581 taagctttag caacctcttc aatatagctc ttatatccct cgtctacata tacagtgagt
     8641 tctttgactt cagatgaacc agaatcagca ggcttatcag cagttttgct tccgcaagct
     8701 accaaaagca agctagcaag tgtagcagtt ccaagcaccg cagtgctctt cataaattta
     8761 gatgacatag tgtattcctc ctaaagaata gcaagtttta ttgataagga aacgcaaacg
     8821 ttttccttta tgagcttagt atagcacaaa tagaaaacgg ttgcaagtat tttttgtaaa
     8881 aattttaaaa aatttttaag cttgatttga tagcataatt ttgcatttta atagaagaaa
     8941 agtatgaaat agataagaat acagtatttt taataaaaat atatggaatc tgtctaaaga
     9001 gggaaatcag gaggggctac ctccctgttt ctaatctata tctattttct atagacgttt
     9061 gtgctttgtt acatataaat tcaagctccc taaggaggtt ttatactttg tagactgtct
     9121 cgtgagagtc aaaccttagg attagatagt tttaagttat ctttgctaaa atgagttagt
     9181 ttccttaaaa ataatcaaaa aagtttttta aaaacgcttg caattatgct tgaaaaggag
     9241 tatacttata agtaacgcaa acgtttgcgt ctgcaaaata cgcaacgttc cattatttta
     9301 acacacgagg tgctattatg aaaaaacgtc aaagtggtgt gttgatgcac atctcttctc
     9361 ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc ttacgacttc gttgatttct
     9421 tggtccgtac aaaacaacgt tactggcaaa tccttccatt aggagcaact agttacgggg
     9481 attctcctta ccaatctttc tcagccttcg caggaaacac tcattttatc gatttagata
     9541 tcttggtgga gcaaggtttg ttggaagcaa gtgaccttga aggagttgac tttggtagcg
     9601 atgcgtctga agttgactat gctaaaatct actatgcacg tcgtcctctt ttagaaaaag
     9661 cggtgaaacg tttctttgaa gtcggagatg ttaaagattt tgagaaattt gctcaagaca
     9721 accaatcatg gcttgagctc tttgctgagt atatggctat caaagagtat tttgacaatc
     9781 ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg taaagcttca gcacttgaaa
     9841 gctatcgtga gcaattggca gacaagttgg tttaccaccg tgtgactcaa tacttcttct
     9901 tccaacaatg gttgaaattg aaagcttacg ctaacgacaa ccacatcgaa atcgttgggg
     9961 acatgccaat ctacgtagcg gaagattcaa gtgatatgtg ggcaaatcca catctcttca
    10021 aaacagatgt caatggtaag gctacttgta tcgcaggatg cccaccagat gagttttctg
    10081 taactggtca gctttggggt aacccaatct atgactggga agcaatggac aaagacggct
    10141 acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat ctacgatatc gttcgtatcg
    10201 accacttccg tggcttcgaa tcttactggg aaatccctgc tggttccgat acagcagcac
    10261 ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc agccgttaag gaagaacttg
    10321 gtgagctaaa catcatcgca gaagaccttg gcttcatgac agatgaagtg atcgaattgc
    10381 gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt tgccttcaac ccagaagacg
    10441 aaagcattga tagcccacac ttggcacctg ctaactcagt tatgtacaca ggaacacacg
    10501 ataacaatac ggttcttggt tggtaccgta atgagattga tgatgcgact cgtgagtaca
    10561 tggctcgtta cacgaaccgt aaagaatacg aaacagtggt acacgctatg cttcgtacag
    10621 tattttcatc agttagcttt atggcaattg caactatgca agatttacta gaattggatg
    10681 aggcagctcg tatgaacttc ccatctaccc ttggtggaaa ctggtcttgg cgtatgactg
    10741 aagatcaatt gacaccagct gtcgaggaag gtttgcttga cttgacaaca atttatcgcc
    10801 gaattaatga aaatttggta gatttaaaga aataagacaa taatcaggag acaactaaac
    10861 atgttatcac tacaagaatt tgtacaaaat cgttacaata aaaccattgc agaatgtagc
    10921 aatgaagagc tttaccttgc tcttcttaac tacagcaagc ttgcaagcag ccaaaaacca
    10981 gtcaacactg gtaagaaaaa agtttactac atctcagctg agttcttgat tggtaaactc
    11041 ttgtcaaaca acttgattaa ccttggtctt tacgacgatg ttaaaaaaga acttgcagct
    11101 gcaggtaaag acttgatcga agttgaagaa gttgaattgg aaccatctct tggtaatggt
    11161 ggtttgggac gtttggctgc ctgctttatc gactcaattg ctactcttgg tttgaatggt
    11221 gacggtgttg gtcttaacta ccactttggt cttttccaac aagttcttaa aaacaaccaa
    11281 caagaaacaa ttccaaatgc atggttgaca gagcaaaact ggttggttcg ctcaagccgt
    11341 agctaccaag taccatttgc agactttact ttgacatcaa ctctttacga tattgatgtt
    11401 actggttatg aaacagcgac taaaaaccgc ttgcgtttgt ttgacttgga ttcagttgat
    11461 tcttctatta ttaaagatgg tatcaacttt gacaagacag atatcgctcg caacttaact
    11521 ctcttccttt acccagatga tagtgaccgt caaggtgaat tgctccgtat cttccaacaa
    11581 tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg aagcaatcga aaaaggaagc
    11641 aacttgcatg accttgctga ctacgcagtt gtccaaatca acgatactca cccatcaatg
    11701 gtgattcctg aattgattcg tcttttgact gcacgtggta tcgatcttga cgaagcaatc
    11761 tcaattgttc gtagcatgac tgcctacact aaccacacaa tccttgctga agcgcttgaa
    11821 aaatggcctc ttgaattctt gcaagaagtg gttcctcact tggtaccaat catcgaagaa
    11881 ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg ttcaaatcat cgatgagagc
    11941 ggacgtgttc acatggctca catggatatc cactacggat acagtgttaa cggggttgca
    12001 gcactccata ctgaaatctt gaaaaattct gagttgaaag ccttctacga cctttaccca
    12061 gaaaagttca acaacaaaac aaacggtatc actttccgtc gttggcttat gcatgctaac
    12121 ccaagattgt ctcactactt ggatgagatt cttggagatg gttggcacca tgaagcagat
    12181 gagcttgaaa aactgttgtc ttatgaagac aaagcagctg tcaaagaaaa attggaaagc
    12241 atcaaggctc acaacaaacg taaattggct cgtcacttga aagaacacca aggtgtggaa
    12301 atcaatccaa attctatctt tgatatccaa atcaaacgtc ttcacgagta caaacgccaa
    12361 caaatgaacg ctttgtacgt gatccacaaa taccttgaca tcaaagctgg taacatccct
    12421 gctcgtccaa tcacaatctt ctttggtggt aaagcagctc cagcctacac aatcgctcaa
    12481 gatatcattc acttgatcct ttgcatgtca gaagttattg ctaacgatcc agcagtagct
    12541 ccacacttgc aagtagttat ggttgaaaac tacaacgtta ctgcagcaag cttccttatc
    12601 ccagcatgtg atatctcaga acaaatctca cttgcttcta aagaagcttc aggtactggt
    12661 aacatgaaat tcatgttgaa cggagctttg acacttggta ctatggacgg tgctaacgtg
    12721 gaaatcgctg agttggttgg agaagaaaac atctacatct tcggtgaaga ttcagaaact
    12781 gttatcgacc tttacgcaaa agcagcttac aaatcaagcg aattctacgc tcgtgaagct
    12841 atcaaaccat tggttgactt catcgttagt gatgcagttc ttgcagctgg aaacaaagag
    12901 cgcttggaac gtctttacaa tgaattgatc aacaaagact ggttcatgac tcttcttgac
    12961 ttggaagact acatcaaagt caaagagcaa atgcttgctg actacgaaga ccgtgacgca
    13021 tggttggata aagtcatcgt taacatttct aaagcaggat tcttctcatc tgaccgtaca
    13081 atcgctcagt ataacgaaga catctggcac ttgaactaat actcttcgaa aatctcttca
    13141 aaccacgtca gctttatctg caacctcaaa gcggtgcttt gagcaacctg cggttagctt
    13201 cctagtttac tctttgattt tcattgagta taagatacaa atttatacta atacatcttg
    13261 taaaaaagcg agtttcgatt gaaattcgct tttttaatga tgtagatttg ggtcaatctt
    13321 gtctaaaaat agggaaatcc tagatacagt gaaggcttta aatgctggtt tttactgtcc
    13381 tcagccttat attttttcgt agttgattac ctcatacctc ttgtattcgc ttacataaag
    13441 tattataata taattgtagg aaagaaggtg tttttatgat atacacactt aaattggtgt
    13501 tgtttattac ctttcttgta ataagcttgt tacctgataa gatttttgga aaaaataaaa
    13561 aaatttggaa aatagttttt gcaatattga cggcagtggc agcattgtca tttatgtact
    13621 aagttatttt aagaatgtag ggaaataaac cctacattct ttttagtttt ttctgttttc
    13681 taaattctat ttatccaagc gcttcaacat ttcttgcttc ttcgcttcaa gttctgcacg
    13741 cttttcttcg atttcggcat gttttttctc gagttcagaa caacttgcac cattgctaaa
    13801 ttcttttcgc catcaggaga tagggtgagt cgacatgtct attactcacc caaagcagtc
    13861 ctacaaagca ggaattttct gttacttttt tggaaatagt aacgtttata cagctttgac
    13921 acttcgtatc aaagcgccaa acacactccg agggatttac agaaagcaga aaaggaatga
    13981 tctggtataa gatcattcct tttctctctt tttctttaag taattatata caatgtacga
    14041 cgaagtcgtc attgcaatgc tgatccacca cctaaaggaa actttaaaca acattgataa
    14101 gataaagaat ataaacaacg aaaatacgtt atacccaatt aattttattg tatatctcat
    14161 gattaaaagt taatccttcc gttgttagga atggcatcat ttttatccca taattgtgct
    14221 aaataagtcc ccggtgataa taaatttata gcaaattcta aagcaacatc atttacaaac
    14281 caactaccta gatatctaga aattgctgaa cgaatagcac tttttgctgc atgttttcct
    14341 tttactttaa ttagatttgc aaggcctgca gtagttcctc ctaatgctaa agctattgca
    14401 gtatctaata gagcacccat ttgattaact gtaatacctt gccaagctgc tctaaatgga
    14461 gagtatgtag gtgggattgt ataatcgcct tgtaattgtc ggttaattac ttctttgatc
    14521 cattgttgtg agacgtctgg atgaaaagat tggatttcgt ttgcaagtgt attgatttgt
    14581 tcttctgtta gagaagtgac aggttgaagt tccatatttg tttcaatttg tgatacttgt
    14641 tcagaagcgt atacagctga aacacttgga atcgctgata caattaacac aattgacgtc
    14701 aaaaaaaccg aaataaattt cattaatttg ttcatgagct tttctccttt ttatttgtat
    14761 ctgcttacat tttatcatat gctgttatta tagtcaaaaa aatatgctat tatgttaaaa
    14821 aaatattttt caaaatataa atggacggat ttattttgga ttttatttgt tattttgacc
    14881 tgcctctata ttggtaacca tgatttgttt actctcaatc atcaagaatt ctcttttcgt
    14941 ggtagcgttt ggggtctggt actggcctta tatcacttac tattcattga taagtttgtt
    15001 atatcgaatc gaaaataaag attagagcta tgcttgactg tgtactttta ggattgattt
    15061 tggaggaaga ttttgtctct attatttatt attttaaatt tatttatttt gtataagatc
    15121 tattctttga ggcgggaaaa atcgaaatac ttgatttata cggcctatat catatttggg
    15181 gtaaatgtag tatatggtat tcaatggtta ttaagagaac tgatttcaac tatttcccct
    15241 taatgtgtat ggaaactata acaaaacgca taagattaag gtttgtgtac ctgttcttat
    15301 gcgtttttat aatattgaag attttcggta agttttatac ctttgggaag tctagtttag
    15361 aatgctttcc caaccaaaat ctctgcttcg atggtaatct ctgtcagttg gctccagtca
    15421 atcttgctct ggtcaacgtg aaagaggaga ggagtcatac tgagtagggc ttggagttgt
    15481 tctgctgtga tagtcttagt cagagaggca gtttgactag ataggatggt aaagtgttcc
    15541 tggaaatgct ccttgatatc ttggttagaa tactccttgt ttgtcagctg gtcctgtact
    15601 ctttgacgga tttctttgag gtgattttca gttgggataa cctttatcaa gataccgtct
    15661 ttggataaaa cgcgacgaaa ttctccatag ttggcaggtg agaagatatc aagcagaata
    15721 tccatgttag cgtcttttat aggaagtcgt gccaagtcgc caacgaacca attgactgcc
    15781 cagttgggtt cacttttagc agcgatttgg actgaatctt tggagatgtc aaaggcatag
    15841 aaagtttttt cagagtgact ttcttgtagt ttgcgagaat agaatccttc accacaaccg
    15901 atatccaaaa ttgttgtggt agtttttgag cttgcaagca agtcagatac agcatctaag
    15961 atagcttggt aaaagccggc ttctaggatt tgttgacggt tttgaaaatt ttccttgtca
    16021 tagttagcag attgcttgat ttgaggtgct agattgacat agccaaattt cgccaagtca
    16081 aaagaatgac ggttgcagca cttgaaatta gtctctaaca gagtcagatt ttcttgacag
    16141 ataggacagg caaaggcagt cgcagaagca aaacgctgaa gtttgggctt gagatttgta
    16201 ttcatagttt aagtgtatca aaagaggcaa atgaaagcaa ctttaggaat aagtagattc
    16261 agtagaaata aaactaattc tccaatttat agaatgaaat tgcttttata tctaaattgc
    16321 tatataataa tgataaggag gaaataagta tgttaaaaga agtattaacc gttgcaaaag
    16381 ttgcgaaaaa atcttcatta tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa
    16441 tcttagcaag taaggaagct aaaaaaggtt attctaaagc tttggctaag gcttacaagt
    16501 tgaaagacga gctagatgca tctgtttctg ttgtgaagca acatggagac gatgtcttgc
    16561 aagatgccaa atatttgtac gagcaagaga aaaaagaaga gcaattagat agccttatag
    16621 gtgaataata tgtcttttaa agtgctacat agaggatacc aacatatccg actatcatct
    16681 tctttttcac ttaccttgga tattcaagac tatcttcgtt ccttggcgag agatgaaaag
    16741 gggattgagt ctatccagtt ttacatggat caacagcact ttactctacg cataaaagaa
    16801 ggcttttctg tattagataa tgcagaagcc tttttaaaaa gaattgataa agggaaagtt
    16861 tctgagttga tgactcttcc cattcgtaga gaagagagtg cttattctat tgtttcaggt
    16921 gcagcggtta agcgtgtact ttttcgtagt tttgtgccgt atcctattcg ctatatatgg
    16981 acttgttatc aggctttggg ttatattaga gaagcctatc aaacactagc gcgtaaggaa
    17041 ctaacgatgg aagtcttgga ctgttcggct attttattgt ccttgtttat gaaccaatcc
    17101 aagacagcta gcaatatcat gtttatgctt gatttgggga atcatttaga tcagtggtcc
    17161 ttgaaaaaaa ctgcaacaga tttagaacag agtcttcttg caaaagagag cgatgtattc
    17221 ctagtacagg gcgatacggt tgttagtatc aagagttccg atgttcaaat aggagatgtc
    17281 ttgatcttat ctcaaggaaa tgaaattctg tttgatggac aagtagtttc aggtttaggt
    17341 atggtcaacg aaagttcctt gacaggagag agttttccag ttgaaaaaag agagtctgat
    17401 ttggtttgtg caaatacagt attagaaact ggagagttac gcattcgtgt aacagataat
    17461 cagatgaaca gccgtatttt acagctgatt gagttgatga agaaatctga agaaaacaag
    17521 aaaacgaaac aacgctattt catcaagatg gcggataaag tcgtcaaata taatttcttg
    17581 ggggctgggc tgacttacct attgacaggt tctttttcta aggctatttc tttcctattg
    17641 gtcgatttct cctgcgcttt gaaaatctct actcctgtag cttatttgac agttatcaag
    17701 gaagggttga accgtgaaat ggtgattaag gatggagatg ttctggagaa atatctggaa
    17761 gttgatactt tcttgtttga taagacagga acaatcacaa ctagttatcc tatagttgaa
    17821 aaggtgttac cttttggaga ctatagtgag gaagatattc tcagaatcag tgcctgtctt
    17881 gaggaacaca tttatcatcc tattgctaat gccatcgtca agcaagctga gatagaggga
    17941 attgaacatg aggaaatgca tgggaaactc caatatatcg caagcaaggg gatcaaatct
    18001 catatagatg gccaaccagt tcttattggg aattatgtct tgatgcagga tgagcagatt
    18061 catatcagtt cagaacaaaa tgctttaatt gaagagtaca agagtcacta caatctctta
    18121 ttcttggctt atcaaaatga attgattgga atgttctgca ttcatactcc tttgagaaaa
    18181 gaagcaaaaa cagccttgga taaacttaag gcacagggga aaaaattgat tctggcaaca
    18241 ggagacacct tgattaggac agaggaatta gtcaaagatt tgccctttga tcaggtctat
    18301 acagacttga aacctgatgg gaaatttgag ttagtagaga aactgcagaa agcaggtcac
    18361 actattttga tggttggaga tggattgaat gactcagcgg ctttaactct atcagatatc
    18421 ggtgtggtga tgaatgagag tgcagatatt tctaagcaga tgagtgatat cttattgtta
    18481 gataatcgtt tggatttctt ccaagagttg gattcgttat catcatcttt gcaaacactc
    18541 atcaagaaaa atattcagga taccgttgtc gtaaatagta gtttgattgg ctttggctta
    18601 tttaattggt tcagtccttc aaatctctct atcttacata atctaacaac cttgcgcatt
    18661 gtcctgcgta gcctgtctat taaaaataga tagatgagag ttattaacag caaaaaggag
    18721 ttacctttct cgaggttaac tcctttgttt atagataaat gttgaatagt ttagtaagtc
    18781 aatacaaagt attttttctt cccacgacgg ataacagtca gttcattttc taacttatca
    18841 gcgtcactca agacatagtc aaggtcttgg atgcggtcgc cgtttacgta gatggctccg
    18901 ttttggacgt cttcacgggc ttggcgtttt gagttaacta taccagatga gacgagcagt
    18961 tccacgatat tgttgttttc gtctgcctgt acttggtagt ttggcacacc acgaagtcct
    19021 tgtttgagct ctttgacaga aaggtttttg atgtttcctg caaagagttg ctcagtgatg
    19081 ttaagtgctt ctttgtaggc ttcttctccg tgaacaagtg taacaacttc acgagccaag
    19141 actttttgag ccaagcgttc gtgtggcgct gcttcaaatt gtttacgaat atcttcaatc
    19201 tcatcaagtg acaagaaagt aaagattttc aagaagcgaa cagcgtcagc gtccatcacg
    19261 ttcatccaga attggtacat ttcgtatgga gaagtctttt cgggattgag ccagacggca
    19321 tttccttctg atttaccaaa ttttttacca gttgcatctg tgattagtgg aacagtgata
    19381 acgtgaccag tcttgtccgc cttacgacga agcaattcgg taccagctgt catatttccc
    19441 cactggtcag aaccaccgat ttgaagagtg acattatggt cttggttaag gacgaagaag
    19501 tcgtaccctt gcatgatttg gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt
    19561 tttttaacag attccttact catcatgtag ttgaccgtga agtactttcc aatgtcacgg
    19621 aggaagtcaa tgaagctgat gctgccaaac cagtcgtagt tgttgaccat gacagccttg
    19681 ttttcgccat tttcaaagtc aagaaaacga gaaagttgtc cttggataga cttgacccag
    19741 ccatctactg tgtcttttgt ttggagacta cgttcagcat ctttgaagga cggatctccg
    19801 atgagacctg tagcaccgcc aacgagcgca taaggtttgt gacctgctag ttgcaagcga
    19861 cgacttgtca agattgcgac aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag
    19921 ccagtataat aagaaacttg accttcttct agggctttac gcaaagcttc ttcatcagtc
    19981 gtttgaaata tcaaaccacg ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc
    20041 tttttaaaat tattgtttct acctattgta tcacaaactt gggcaatagc ctagcagaat
    20101 agggaagaaa gtggctattt tattgaaaat ttcccttttg tggtataata gataaagtga
    20161 ggaaatccat gcaaaatcaa ttaaatgaat taaaacgaaa aatgctggaa tttttccagc
    20221 aaaaacaaaa aaataaaaaa tcagctagac ctggcaagaa aggttcaagt accaaaaaat
    20281 ctaaaacctt agataagtca gccattttcc cagctatttt actgagtata aaagccttat
    20341 ttaacttact ctttgtactc ggttttctag gaggaatgtt gggagttggg attgctttgg
    20401 ggtacggagt ggccttattt gacaaggttc gggtgcctca gacagaagaa ttggtgaatc
    20461 aggtcaagga catctcttct atttcagaga ttacctattc ggacgggacg gtgattgctt
    20521 ccatagagag tgatttgttg cgcacttcta tctcatctga gcaaatttcg gaaaatctga
    20581 agaaggctat cattgcgaca gaagatgaac actttaaaga acataagggt gtagtaccca
    20641 aggcggtgat tcgtgcgacc ttggggaaat ttgtaggttt gggttcctct agtgggggtt
    20701 caaccttgac ccagcaacta attaaacagc aggttgttgg ggatgcgccg accttggctc
    20761 gtaaggcggc agagattgtg gatgctcttg ccttggaacg cgccatgaat aaagatgaga
    20821 ttttaacgac ctatctcaat gtggctccct ttggccgaaa taataaggga cagaatattg
    20881 caggggctcg gcaagcagct gagggaattt tcggtgtaga tgccagtcag ttgactgttc
    20941 ctcaagcagc atttttagca ggacttccac agagtcccat tacttactct ccttatgaaa
    21001 atactgggga gttgaagagt gatgaagacc tagaaattgg cttaagacgg gctaaggcag
    21061 ttctttacag tatgtatcgt acaggtgcat taagcaaaga cgagtattct cagtacaagg
    21121 attatgacct taaacaggac tttttaccat cgggcacggt tacaggaatt tcacgagact
    21181 atttatactt tacaactttg gcagaagctc aagaacgtat gtatgactat ctagctcaga
    21241 gagacaatgt ctccgctaag gagttgaaaa atgaggcaac tcagaagttt tatcgagatt
    21301 tggcagccaa ggaaattgaa aatggtggtt ataagattac tactaccata gatcagaaaa
    21361 ttcattctgc catgcaaagt gcggttgctg attatggcta tcttttagac gatggaacag
    21421 gtcgtgtaga agtagggaat gtcttgatgg ataaccaaac aggtgctatt ctaggctttg
    21481 taggtggtcg taattatcaa gaaaatcaaa ataatcatgc ctttgataca aaacgttcgc
    21541 cagcttctac taccaagccc ttgctggcct acggtattgc tattgaccag ggcttgatgg
    21601 gaagtgaaac gattctatct aactatccaa caaactttgc taatggcaat ccgattatgt
    21661 atgctaatag caagggaaca ggaatgatga ccttgggaga agctctgaac tattcatgga
    21721 atatccctgc ttactggacc tatcgtatgc tccgtgaaaa gggtgttgat gtcaagggtt
    21781 atatggaaaa gatgggttac gagattcctg agtacggtat tgagagcttg ccaatgggtg
    21841 gtggtattga agtcacagtt gcccagcata ccaatggcta tcagacctta gctaataatg
    21901 gagtttatca tcagaagcat gtgatttcaa agattgaagc agcagatggt agagtggtgt
    21961 atgagtatca ggataaaccg gttcaagtct attcaaaagc tactgcgacg attatgcagg
    22021 gattgctacg agaagttcta tcctctcgtg tgacaacaac cttcaagtct aacctgactt
    22081 ctttaaatcc tactctggct aatgcagatt ggattgggaa gactggtaca accaaccaag
    22141 acgaaaatat gtggctcatg ctttcgacac ctagattaac cctaggtggc tggattgggc
    22201 atgatgataa tcattcattg tcacgtagag caggttattc taataactct aattacatgg
    22261 ctcatctggt aaatgcgatt cagcaagctt ccccaagcat ttgggggaac gagcgctttg
    22321 ctttagatcc tagtgtagtg aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga
    22381 aggtttctgt tgaaggaaaa gaggtagagg tcacaggttc gactgttacc agctattggg
    22441 ctaataagtc aggagcgcca gcgacaagtt atcgctttgc tattggcgga agtgatgcgg
    22501 attatcagaa tgcttggtct agtattgtgg ggagtctacc aactccatcc agctccagca
    22561 gttcaagtag tagttctagc gatagcagta actcaagtac tacacgacct tcttcttcaa
    22621 gggcgagacg ataattctct aaatgaagtg gccaatcaat ggattgccac ttttttcctt
    22681 tcgtgttaca ataagggtat gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat
    22741 tcgctcctat ccggcttaat atggggaatc tgtggaattt taggagagta cttctttact
    22801 cattatcagg tgtcttcggg ctggattacc tctatgcgtt tgacactggc agggagtctt
    22861 gtactcattt ggtctgcaat acaattaaaa tcgcaagtgc tagatatttg gcgagacaag
    22921 aaaaattacc tgcccttttt agcctatgct attttgggga ttttttcagt tcagtatttt
    22981 ttctatctct gtttagaata ctcaaatgct acgacagcaa ctattttaca gtttattagc
    23041 cctgtcttta tcctctttta caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct
    23101 gttttctatg ttttggttgc catgctgggt gtttgcttga tggcgacaaa gggagatctc
    23161 tctcagttat ccatgacgcc gctagctctt ataacaggtt tgctgagtgc catgggtgtt
    23221 atgtttaatg ttatcttgcc ccaacctttt gctaagcgtt atggttttgt tcctacggtt
    23281 gggtggggga tgattttggc aggtttgttt agcaatgtcc tctcgccggt ttatcagctt
    23341 tcctttactc ttgatatttg gagtatcttg atttgcctca ttatcgcttt ctttggaacg
    23401 gcttttgctt ttttcatttc catgaaggct gtgtccttgg tttctccttt ggtggtttcc
    23461 gttatcagtg ccagtgaacc tctctcttct gctctcttga gtgttttgtt cttaggatta
    23521 gtagtggatt ggtccctcct tctagctata gccttgatta ttttacccat gatatttttg
    23581 tctatagaag aagcgaaaga aagtagataa aaagtctttt cttaattcta aaagtgtgct
    23641 atactagaat agtcaataaa acacggggag atagttgtga agagtatttt taggttgtat
    23701 cggtaggggc ttgcttttac cgacagcacg ttttatctca catccctaaa aaatcatacc
    23761 taaaaacaga caaaaaggtt tcaaatttga ggcctttttt ggtagaatag gtatcattat
    23821 aacgaaccag gaggcaccta tgactgctac aaaaatgaac gctcaagaaa ttatccaatt
    23881 tatcgccaat gctgaaaaga aaaccagtgt caaagtaacc tttgaggggc aactcgcaac
    23941 tgctgtgcct agctctgttg tcaaactagg aaatgtccta ttcggagact ggaaggacgt
    24001 ggctccgctt cttgaaggtt tggtagaaaa tcaagattat gttgtcgagc aagatgctcg
    24061 taattctgca gttcctttgc tagataagcg tgctatcaac gctcgtatcg agccaggtgc
    24121 tattatccgt gaccaggtgg aaattggtga caatgctgtt atcatgatgg gagctgttat
    24181 caatatcggt gctgaaatcg gtgctggaac catgattgac atgggtgcca tccttggtgg
    24241 ccgtgctatc gttggaaaaa atagccacgt tggtgcaggt gcagttttgg caggtgtgat
    24301 tgagccagct agtgctgaac cagtctgtgt cggagacaat gttcttatcg gggctaatgc
    24361 agtggttatc gaaggagtcc aaatcggtag tggttcagtt gtcgctgcag gagctatcgt
    24421 tacccaagat gtcccagaaa acgtggtagt agcaggtgtt ccagctcgta ttatcaaaga
    24481 aattgatgcc caaactcaac aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt
    24541 gtaaaagtaa aaaagaggcg gaaccctttt tccagcctct ttctgctata tcggaggaca
    24601 gatagatgtt agatttgatt cagactagac gagctttaca ccagattcca gagattggct
    24661 tggaggagtt caagactcag gcttatttgc tggatgtgat tgagaaattg actacgggca
    24721 aggattttgt tcaaattcgt acttggcgga cagggatttt ggtctacctg cagggaagtc
    24781 agccggagcg aaccattggt tggcggacag atattgatgg cctgcctatc gtcgaacaaa
    24841 caggtctacc ttttacttct caacaccaag gtcgcatgca tgcctgtggt catgattttc
    24901 atatgaccat tgccttaggc tgtcttgagc gcgcccttga ggagcaaccc aagaataatc
    24961 tgctctttct atttcagcct gctgaagaaa atgaagctgg tggtatgctc atgtatgagg
    25021 acggtgcttt tggagattgg ttgccaaacc aattctatgg tctccatgtt cgtccagatt
    25081 tgaaagtcgg ccagattgcg actaatactc atacactctt tgcaggaact tgcgaggtga
    25141 agatccgttt caaaggtaaa ggtggccacg cagcttttcc tcatgaagcc aatgacgcct
    25201 tggtggcggc tagttacttt gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc
    25261 caatcgaggg agcagtggtg accttcggcg tttttcaagc tggaaccacc aacaatgtca
    25321 tcacagacac agctttttta catggaacta ttcgtgcctt gacacaggac atgagtctct
    25381 tggtgcaaaa gagggtaaaa acagttgcag aaggggttgc agctgccttt gatatggaag
    25441 tcgaagtgga actcaaacaa ggtggatacc tacctgttga gaacaatcca gccttggcgc
    25501 gtgaactgat ggacttcttt gacgagaaag acggaatcga gttgattgat atcgaacctg
    25561 ctatgacagg cgaggacttt ggttatctcc tttcaaaggt tgatggcgtg atgttttggc
    25621 taggtatcga tagtccctac gctcttcatc accctcaaat gagtcctaag gaagaagtct
    25681 tagctattgg ggtggctgcg gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg
    25741 cttgtctatg aaatcggaat tacgcaagca agtcttgcat gaaatgaagg ctatatctca
    25801 agagcaaaaa caggctatag accaagcttt aaccgagcga attttacaac acccctttta
    25861 tcaagaagcc aaggtcatcg caacctacct ctctttttct catgagtttc aaacgcggga
    25921 actgattgag caggcgctga aggacggcaa gaaggttttg acacctaaga cctatcccaa
    25981 ggggcgcatg gattttgtgg tctatgatcc gcaacagttg gtaaaaactt cctttgcctt
    26041 actggagcca cagggagatt tggaagtagt ggatgcatct cagattgatt tgattcatgt
    26101 tcctggcctg gcttttacga cggatggata tcggattgga tatggtggag gttattatga
    26161 ccgctatctg gaacattttt ctggtcgtgc tttgagtacg atatatcctt gtcaaattca
    26221 ggactttata cctgaaaacc atgatattcc tgttcaggag gtattaattg atgaaggaaa
    26281 tctttgatag acgttaccct gtgacgagtt tcttcctctt agtgacggcc ttggtatttt
    26341 tactaatgtt ggtcactgca ggcggaaact ttgacagggc agatacatta tttcgatttg
    26401 gagccatgta tgggccagct attcgcctct ttcccgagca ggtttggcgt ctcttgtctg
    26461 ccatttttgt tcatattggg tgggaacatt tcattgttaa tatgctttca ctttattatc
    26521 ttggaaggca ggtagaggag attttcggtt ctaagcagtt tttctttctc tatcttttat
    26581 caggaatgat gggcaatctc tttgtttttg tatttagtcc taaatcctta gcagcaggcg
    26641 cctctacctc tctttatggg ctatttgccg cgattattgt tcttcgctat gcaactcgca
    26701 atccttatat tcaacagcta gggcaatcct atctgacact ttttgtagtt aacattattg
    26761 gaagtgttct gattccagga atcagcctag caggccatat cggtggtgca gttggtggcg
    26821 catttctagc agttatcttt ccagttagag gagaaaaacg gatgtataat accagccaga
    26881 gattaggagc ggtagtcttg ttcgtaggac tcgccatttt gcttttctac aagggaatgg
    26941 gaatgtgacg aagttgaaag aaaatttgtg taatgaaaaa agataaggca ttttttgaac
    27001 cttatctttt tattttattt tattccttct cagtcaattc ttttccaagt tggatgaggt
    27061 aattcttcaa atcatctttg acttgtgggt gtttgagggc gtagtcgatg gatgttttca
    27121 tgaagccaaa cttgtctccg acatcgtaac gagccccatt gaactcacga gcaaatacac
    27181 gttgtgtttt attgagggtg tcgattgcat ctgtcagctg aatttcattt cctgcacctg
    27241 gagcttggtt ttcgaggatt tggaaaattt caggcgtgag gaggtagcgt ccgataatag
    27301 caaggtcgct aggagcgtcc tctggagctg gtttttcaac aaaggtttca acactgtaaa
    27361 gaccatcttt tccttcgcct tgcggagcaa taaccccgta agcagatact tcgtcatgag
    27421 ggactggcat gacagcgata gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt
    27481 tggtaagtgg aacagccttt tcgtctgtga tatccatcaa gtcatcacca agcataacga
    27541 caaaaggttc atttccgacg aaagccttag cttgcaaaac agcatctccg agaccgcgtg
    27601 gatgagtttg gcggataaaa tgcagacgca tgtcagttgt tttatcaact agcttcaaaa
    27661 gatctgtttt ccctttttct ttgaggttat attccaattc gaagtttgaa tcaaagtggt
    27721 cctcaataga acgttttgat ttaccagtga caactagaat atcttcaata cctgatttga
    27781 gagcctcttc cacgataaac tggatagttg gtttgtctac gattggcaac atttctttgg
    27841 caagggcctt ggttgctggt aaaaatcgag ttcctagtcc agcagcaggg atgactgcct
    27901 ttctaacttt tgatgtcata aaaatccttt ctatagaggg ttaagaccac tcattttctg
    27961 ctttaaattc attgttcatg atgtcataaa tggcatcttt gatattggtt ccgtgataaa
    28021 taacttggta aatagcctgt gtaatgggca tatagactcc aagttcttgg gctagttcat
    28081 aggctgctcg agtcgttgaa attccttcga ttaccatgcc catattagct tctatatcag
    28141 ctagggattc tcctcgtccg agagcatctc cagctctcca gttacgagag tggatggaag
    28201 ttcccgttac gatcaaatct cccacaccag ataagccgct ataggtcaat ggactggccc
    28261 cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg agcgatgatg gctgccttag
    28321 cattatcacc aaatccaaga ccatgtaaag ctccagcacc gacagcaata atatttttaa
    28381 gagcaccagc agtttcaacc ccgataacat ccgtattggt ataaagtcgg aagtagtgat
    28441 tactaaatag ctcctgaacg tattgagctg tttgtaaatc tttagaagca gcagtgatta
    28501 aagttaggtc acgcacaatg gtttcttccg catgactagg ccctgaaaca acgacaatat
    28561 cactgcggag ctgttcagga atttcttctt caaggatagt tgataatcgt ttatggctat
    28621 caggttctaa tccctttgaa gcgtgcatga tgatagcctt atggtccaag gtttgtgcaa
    28681 cttgttgggc aacaagtcgt gtcacttttg ttgggacaac aaacaaaatc gcatccacat
    28741 ctttcaatgt ttctgctaag tcggtgtagg caatgatatt ttcatctaga acgacatctt
    28801 taaagtagtg cttgttagta tgataggtat taatttcatt gatttgctcg ggaagatttc
    28861 cccaaatacg tacctcgtgt ccattgtcat ttaagacttg tgaaagggca gttccccaag
    28921 aaccaggccc caagacggcg acggtttgtt tttccatgat ttcctccttg atagagttct
    28981 ttccattatt ctatcatatt ctagaggatt ttgcacttgc attactgggg tatggtggaa
    29041 aaatacacaa agaccgagat gaagggataa actcttagtc tttagttaaa gtgagaagaa
    29101 atctgataga tagtttgatt cagtatatgc tataaataga ggtaaacaac tcaggaggtt
    29161 cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca
    29221 gtcgttcaga attttgtggt gatgagtctg aattaagtat ccgtcaatta attagaattg
    29281 aaaatggaga atccagacca acactaacaa agttaaaata tatcgctgaa cgtttggggg
    29341 gggtgaagat tacaagttga tgccaagtta tatagagttg gataaggaat acctagaatt
    29401 gaagtatttc ttgatgagga ctcctacata cgaagatgaa actatcgccc aaaagaaaga
    29461 gagtgttttt gctaagattt ttgaagagta ttatgatagg ctacctgagg aagaaagatt
    29521 tatcatccca aattattcat atctagcact agcgaactac acagttcaaa aattaccaga
    29581 aaagctagtt gaaatactgt ccttctggtg attttgctta atttctgatg ttcgagacat
    29641 gattgaggag atttgtcttg attttttcct aaaaaagggc agactcctcc cttggtttga
    29701 tgctcgattt ttaaaataag gtgacttatt ctgttaggca tgttttcccc tgccctctag
    29761 ctctatatgg aacagggagt atcagattta tctggcagat tgtatcaaat aaggcttgaa
    29821 actgttttga ataggcgtat agacttgaga atttgagaat atgtcgtcta gcagtagaga
    29881 catattttcc ggcaatatga aggaagagac gtcgaaaacg cttgatagtc aaggacttta
    29941 cttcatcacc agctagctgc tttaaaaaga ggtagagatt ataagccaga cagcccatca
    30001 tcatacgtac ttcattctta atcatggtcg aactatctgt cttatcccca aagaatcctg
    30061 ctttcctttc tttgataaag ttttcagcat tccctcgttc acgatagaat tgaaacagct
    30121 cctcactatc tacactgctt aaattgttca aatgaacttt tttacaacca taaaaaagag
    30181 cacttaatcg tactcttctc ttttaaggat tagttgaatt aattcaaatc cactagttct
    30241 cctgtttcta ggtagactag gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc
    30301 agatgtccta tgatataaag gtattgagtt ccattgggaa ttgaggtttc ttggtctttc
    30361 ataagtccaa tgatttcctt tgataaggca taataatatt ggtcaatctg ttcatctttt
    30421 tgagcaatac taatagcttt tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct
    30481 agcatgctga gggataattt acccatttgg tgtaactgtt cttcgtcagg ggctagttga
    30541 ttttctttta gttgcaaaac agctttggca atgcctgcca tatggtctcc catacgttca
    30601 aggtctgaac aagaagacat gatgctaatc acaaatcgaa ggtcagacac ttgtggctgt
    30661 tgcaaggcca acaaacgggc acaggtcaat tcgatagcgc tttgaccttg gttgatagca
    30721 tgatccttat tgataattag ctctgccatc tccttgtctt tggaggctaa ggccagtaag
    30781 gcttttgaag ctgtttcaag gacaagttgc cctagtccta aaaaggattg ttctaattca
    30841 tgcaattcta agtcaaattg atttctcata ggtttttcct tccttatccg aaccgtcctg
    30901 aaatatagtc ttctgtgcgc tgatcttttg gattggtaaa cacgtcaacg gtatctccaa
    30961 attcgcaaat ttctcctgtt aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt
    31021 gcatgttatg ggtaacaatg ataatcgtat aatccttttt tagttgctga atgaggtctt
    31081 caatttttaa agtggagata gggtctaagg ctgaagtcgg ctcatccatt aacagaacat
    31141 caggttctac tgctaaagct cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg
    31201 acatggcact ctttttaaga tcatctttga cttcttccca aatggctgcc ccttttaaag
    31261 atttctccac taaggcatct aattgttttt tgtctcgaat accatgtgtc cttggaccat
    31321 aagccacgtt atcatagata gacatggcaa agggattagg ctgttgaaaa accatcccta
    31381 cacgcttgcg tagctgatta aggttgaatt tgctactata aatatcttgc tcatctaaga
    31441 ggacttggcc ttcaatatgg caagaaggaa ccaaatcgtt catccggtta agggttttta
    31501 gaaaagttga tttgccacaa ccagatgggc ctatcaaggc agtaatctgt ctttctggta
    31561 attgaatcga aatatttttt aaggcttgaa aatccccgta aaataagtct aggtgtctga
    31621 ctgaaaatgt tcccatacta ggaagctcct ttcacaagtt ttcgagataa taagcttgat
    31681 agagtattta tcattaaaac agtaataatc aaaatcacac cggtagcata ggcttcattg
    31741 acatgtagcc cctcacttga cagcatatac atatgcaggg ctagagaacg acctgaagac
    31801 atgagactac ttggcgtatt ggtagaggta cctaatgtat acatgagggc agctgtctca
    31861 ccaacgatac ggccaatagc tagtatcact ccagctaaaa tacctggcat ggcaactggt
    31921 agaacaattc taaaaacagt ccgtaactta cctgccccaa gtccataact tgcttgacgc
    31981 atgctatcac taacagataa aagggcttct tctgttgagc gaataatgac tggcaacacc
    32041 atgatgactg aggttaagat tcctgataac agagagtatt gaaaacctaa gaagactaca
    32101 aagaagagca tgccaaacag accaaaaaca atggaaggaa tcccagacaa ggtatctgag
    32161 gccaatcgca tgattttaac acaaagggaa tctttttttg tatattccac aagataaaaa
    32221 ccagcaaaaa tccctatggg caaggctaaa agaagagcac caaagaccag aataacggtg
    32281 gaaataatcg ctggcataag ggaaatgttc tcagaagtat aagtccaaga aaagagggat
    32341 agacttagat gaggtaagcc tttgatgagg ataaaaccaa tgattaaaaa gagagagcca
    32401 aaggttaaag ctgaaaaaca ataaacgaga agttttagca ggtatttact cataagatga
    32461 ttttcctttc aagtaggcaa agtaggcatt aatcaagaga ataaggaaaa agagaactgc
    32521 tgaggttgca ataagggctt ccctatgctg acctgatgcg taagccattt ccagaacaat
    32581 attggttgtt aaggttctgg ttcctgaaaa gagtccactt ggaataatcg gctggttgcc
    32641 tgccaccaaa ataactgcca tggtttcacc tactgcgcga ccgattccta aaataactgc
    32701 tgataaaata ccagatctcg cagctggcaa gatgacacta aaaatactcc gttcatgact
    32761 agctcctaga gccaagctac cagaataata cgttttggga actgttcgga tagcagattc
    32821 tgacaaactg ataatggttg gcaaaatcat tattcctaat agtaacgaag cggttaggac
    32881 actcatgcca tttcctaaaa aggttctaat ccaaggcacc aataattgta ggccgaaaaa
    32941 accataaaca atagatggaa tggccgccat caagttgata gctgatttta agaagccata
    33001 gacgggcttt ggacaataat aaaccataaa caccgatgtc aagatgcctg ttggcacccc
    33061 aatcacaatc gctcctaagg taattaataa ggaaccaacg atcattggta aaataccata
    33121 gcttgccgga atgttcgttg gcgaccaatc actgcctaat aaaaaacggg caaagccgta
    33181 gttagccatg aaaggtaagc cattactaaa aataaagaaa cagattagca aaatagctac
    33241 aacagctact gttgcactca tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg
    33301 ttttgtcaca tcttgtcctt tctagtgaag aaagtaaggg agatacgaca cctccctact
    33361 tgccttcttt atcttattgt acgatgaaac gtctgcatct ctttagagat ttatggagca
    33421 aacattttat ttaatcttgt cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc
    33481 agccatactg acttggcttg ccttattgtc attattgacc acaacagcaa taccgtctaa
    33541 agcaatagca tcatgggtga gactcttacc ttcttcagga gttaattccc tagaaaccat
    33601 accaatatca gcggttttct ccttaacagc ggtaatacct gctgaagacc cattagaggt
    33661 aatatcaatc gtaacttctg gattttcttt tttataagct tctgctaatt tttccattaa
    33721 agaagatact gaagtggaac ctacaacaga caacttgcct gataagtgtt ggcttgtata
    33781 ttctgtggtt tcggttttag cttcaataaa tttattatct gtgaccactt gttgaccttg
    33841 tttggagtgg ataaagctga taaaatcttg acctagcttg gaaagattag aagaccaaac
    33901 aatgttgaag ggacgttgaa gagggtattc accatctaaa actgtgtctc gactagcctt
    33961 gacaccatca atctctaaag ccttgacaga tttcgttaaa gatcccaagg agatgtagcc
    34021 gatagcatta gcattccctt gaactgctga gagaacacct tctgtactat tttgaatcac
    34081 agctgttttg gcagtgttgt caattttttt atcaccgtct tttttgagaa tccctgtgat
    34141 ttctgtgaag gcaccccgtg ttccagagcc attttctcgt gaaatcacct caatcgttcc
    34201 tgaagctgac tgtttggaag cagctgactg attgccacag gcaacaagcc caaatcctga
    34261 taagccaatg gctgcaagag taagcatttt tttgaatttc ataataatca cctttatctc
    34321 tatgtatttt tcttgtgtag gcttactaca tttatagtct aacaagtctt tgtaaaggtt
    34381 tatccctgat tcatgtaaag attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg
    34441 ctgctcctaa aaatagcttt aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa
    34501 aaatcgtgaa gcaactgcct ctgccaagct gactcgtcac cgtgacttgg ccacctaata
    34561 attgactgag ttctttgaca atggcaaggc caagaccagt gccaccagtt tgtctgcttc
    34621 gacctttatt aactcggtaa aaacgttcaa aaatacgatc ctgctctaat tgactaatac
    34681 caatccctgt atctgataca gaaatcttaa tgccttcgtt caccttttgg gtcttgacct
    34741 caatttttcc cccttgttca gtgtaacgga tggcattgga taaaagattg agtaagattt
    34801 gggaaagtaa ttgactatct gatacgaggg tgacatcatc tggcacctgc acctttagct
    34861 gtaaatcctt cttcttgagc tgaggttgca agctttgagt caaatcctgt acaaattctg
    34921 ccaaagaaag ggtcgtccat tgtataggca tttgttgagc cttagataag gtaagaagat
    34981 gctcaacaat atgctcaaga cgcaagcttt ctttgtaaat aatgtctaga aagtcatcct
    35041 tgagcgcttc ttcttcagct gacatcccct taatggtttc agcaaagccc ttaatcgaag
    35101 taactggtgt cctcaattca tgggaggcat ttgagacaaa ggctaaattt aacttttcat
    35161 aagttctaat cgttgttaaa tcatatagca agacgagcac agcttccaca gattgggtgg
    35221 ggctaaaaac gggaactgct gtcacttcta aaatcaagtc accctcatga aacccactta
    35281 cttcttgttt taaccttgtt ttttgatcaa aggcttggtg aactaaattt cgaatatcca
    35341 tccgtttgag gtcatcaagt gaacttatgt cgccgtccac atcgggaaaa taatgaggca
    35401 gagagcgact ggataataac atctgacctt gagcggaaac taaaaacgtc cccatggtta
    35461 ggtgcgacag aagaacctcc attgtttcgg ctaggtcctt gtattgctga tcctgttggg
    35521 agactttggt ttttagggca gacacatact gagccaaaga ctttaagtct tcttgccctt
    35581 tttctaaaaa gtattcacta ctggtcaaga gaggttggtg caaggtctca aaagcaactt
    35641 cccatttcca aaggcaaaag agccagtagc caccttgtcc caaagaaagg gctagaagaa
    35701 agagaccgat gcctttactg atccaagtta atgccatccc tgcaatcaga atgaggctaa
    35761 cacttagatt gactagccaa aattgaaggt agcgtttcat ctataactcc ttgaacttat
    35821 aaccataacc ccgaatggtt cgaataaatt gaggggcttt aggattgtct tcaatttttt
    35881 ccctcaactt accaatatga acgtccacca aacgtgtttc ctgcccaaag tcataccccc
    35941 agatacgttc caaaagacgc tctctagtca gtgtcatgtt gggatgtttc ataagataga
    36001 gcaagagttc aaattctttt ggggtcaaac tcagtaactt attcgccttg tagacttcat
    36061 gacgctcagg gtatactttc aaggtcccaa atagccaaga atcgtcagcg atattatctg
    36121 aatcatctcc ttcttgttct cctttagttc gcctgaggac agccttgaca cgcgccagca
    36181 attctctagg gctaaaaggc ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa
    36241 ccttatcaaa ttcatcactt ttcgcagaaa ccatcataat tggagttttg acgcctttgg
    36301 ctctcagccg cttacaaact tccatgccat ctaattgtgg taacatgata tcaagcaaga
    36361 taaaatcaaa gggttctgtt tctgccaaag ctaaggcctt ccgtccattt gttaccaatt
    36421 gagtagaaaa gccttcctta cttaaatggt agtcaagcaa tttcagaatg tgttcttcat
    36481 catccactaa taagacttgt tttgtcatct attatctcct attggtaaca ttataacaca
    36541 attatcagaa atcctaacat tgctaaatca gattaaattt gcttatcaag actagtatct
    36601 ggtcaaacgc tcaatcatct ccttgtgctc tggataggtc gccagtagat ctaccctttc
    36661 aaataattca aaatcctcaa attcaaaacc aggagcaaca agacaagaaa ccagagcata
    36721 atccttatca actgttgatc cccaaatagt gcccttagga acacagtagt gaagttgttg
    36781 ccctttggat atgtccaggc ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat
    36841 gtgaacagta agtggggatc ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg
    36901 aaaatgtgaa ggattcgttt cttctaataa gaaataaata ctggtataaa gcgcccttcc
    36961 cttaccagca aggtttatag tgtctgaagc tttttttgtt tgtctaaaat agccaccttc
    37021 aacatgggga gctaactcta gagttcttat caagtcttct ttatccgtcg gagccaatgg
    37081 gttgaagtaa ctcttgttca aaggtggtgt tacgatttca agaactcctc tcagctctga
    37141 ggacacgata atgattgatg cgacggaagt acaaatcaat cgccctaaaa aaagaattag
    37201 cgaattattc tggtaaa
//
LOCUS       DAVBED010000016        34466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBED010000016 DAVBED010000000
VERSION     DAVBED010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.016"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            143..361
                     /gene="infA"
                     /locus_tag="VQ547_000806"
     CDS             143..361
                     /gene="infA"
                     /locus_tag="VQ547_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2542680.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            386..502
                     /gene="rpmJ"
                     /locus_tag="VQ547_000807"
     CDS             386..502
                     /gene="rpmJ"
                     /locus_tag="VQ547_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2542681.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            520..885
                     /gene="rpsM"
                     /locus_tag="VQ547_000808"
     CDS             520..885
                     /gene="rpsM"
                     /locus_tag="VQ547_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2542682.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            903..1286
                     /gene="rpsK"
                     /locus_tag="VQ547_000809"
     CDS             903..1286
                     /gene="rpsK"
                     /locus_tag="VQ547_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2542683.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            1329..2264
                     /locus_tag="VQ547_000810"
     CDS             1329..2264
                     /locus_tag="VQ547_000810"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2542684.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ547_000811"
     CDS             2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ547_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2542685.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            2927..3193
                     /locus_tag="VQ547_000812"
     CDS             2927..3193
                     /locus_tag="VQ547_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2542686.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            3203..4540
                     /locus_tag="VQ547_000813"
     CDS             3203..4540
                     /locus_tag="VQ547_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2542687.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            4784..5476
                     /locus_tag="VQ547_000814"
     CDS             4784..5476
                     /locus_tag="VQ547_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2542688.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(5579..7224)
                     /locus_tag="VQ547_000815"
                     /pseudo
     CDS             complement(5579..7224)
                     /locus_tag="VQ547_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7214..7519)
                     /locus_tag="VQ547_000816"
                     /pseudo
     CDS             complement(7214..7519)
                     /locus_tag="VQ547_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(7646..8305)
                     /locus_tag="VQ547_000817"
     CDS             complement(7646..8305)
                     /locus_tag="VQ547_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542689.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(8318..9439)
                     /locus_tag="VQ547_000818"
                     /pseudo
     CDS             complement(8318..9439)
                     /locus_tag="VQ547_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(10027..10803)
                     /locus_tag="VQ547_000819"
     CDS             complement(10027..10803)
                     /locus_tag="VQ547_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2542690.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            10925..11671
                     /locus_tag="VQ547_000820"
     CDS             10925..11671
                     /locus_tag="VQ547_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2542691.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            11684..12664
                     /locus_tag="VQ547_000821"
     CDS             11684..12664
                     /locus_tag="VQ547_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2542692.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            12859..13179
                     /locus_tag="VQ547_000822"
     CDS             12859..13179
                     /locus_tag="VQ547_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2542693.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            13225..13533
                     /locus_tag="VQ547_000823"
     CDS             13225..13533
                     /locus_tag="VQ547_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2542694.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            13550..14848
                     /locus_tag="VQ547_000824"
     CDS             13550..14848
                     /locus_tag="VQ547_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2542695.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            14999..17437
                     /locus_tag="VQ547_000825"
     CDS             14999..17437
                     /locus_tag="VQ547_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2542696.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            17456..18124
                     /locus_tag="VQ547_000826"
     CDS             17456..18124
                     /locus_tag="VQ547_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2542697.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            18142..19230
                     /locus_tag="VQ547_000827"
     CDS             18142..19230
                     /locus_tag="VQ547_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2542698.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            19685..22186
                     /locus_tag="VQ547_000828"
     CDS             19685..22186
                     /locus_tag="VQ547_000828"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2542699.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            22380..23075
                     /locus_tag="VQ547_000829"
     CDS             22380..23075
                     /locus_tag="VQ547_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542700.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            23087..23503
                     /locus_tag="VQ547_000830"
     CDS             23087..23503
                     /locus_tag="VQ547_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542701.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(24130..24222)
                     /locus_tag="VQ547_000831"
     CDS             complement(24130..24222)
                     /locus_tag="VQ547_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2542702.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ547_000832"
     CDS             24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ547_000832"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2542703.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            25335..25907
                     /locus_tag="VQ547_000833"
     CDS             25335..25907
                     /locus_tag="VQ547_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2542704.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            26138..26896
                     /locus_tag="VQ547_000834"
     CDS             26138..26896
                     /locus_tag="VQ547_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2542705.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            26905..27708
                     /locus_tag="VQ547_000835"
     CDS             26905..27708
                     /locus_tag="VQ547_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2542706.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            27730..28989
                     /gene="rseP"
                     /locus_tag="VQ547_000836"
     CDS             27730..28989
                     /gene="rseP"
                     /locus_tag="VQ547_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2542707.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            29002..30855
                     /locus_tag="VQ547_000837"
     CDS             29002..30855
                     /locus_tag="VQ547_000837"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2542708.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            30955..32334
                     /gene="bglA"
                     /locus_tag="VQ547_000838"
     CDS             30955..32334
                     /gene="bglA"
                     /locus_tag="VQ547_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2542709.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            32526..34334
                     /gene="glmS"
                     /locus_tag="VQ547_000839"
     CDS             32526..34334
                     /gene="glmS"
                     /locus_tag="VQ547_000839"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2542710.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT        10494 a         5881 c         7579 g        10512 t
ORIGIN      
        1 aaaaagtatt gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa
       61 tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg
      121 aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt
      181 agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt
      241 agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt
      301 tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata
      361 atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga
      421 atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa
      481 acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt
      541 gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt
      601 gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat
      661 cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt
      721 gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt
      781 ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa caacgctcgc
      841 actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag
      901 tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc
      961 atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa
     1021 ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg
     1081 ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag
     1141 ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg
     1201 ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc
     1261 gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga
     1321 gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt
     1381 atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc
     1441 ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg
     1501 gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc
     1561 tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg
     1621 atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa
     1681 ttgtaaatcc agatcattat ctctttacaa ttggtgaagg ttcttctcta aaagcgacta
     1741 tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac
     1801 cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag
     1861 tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga
     1921 caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac
     1981 atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag
     2041 ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg
     2101 tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa
     2161 aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga
     2221 aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc
     2281 ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac
     2341 tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa
     2401 aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc
     2461 agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta
     2521 cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg
     2581 taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat
     2641 ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct
     2701 tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat
     2761 cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg
     2821 taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct
     2881 gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat
     2941 aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga
     3001 attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat
     3061 ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc
     3121 ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat
     3181 gtataatatc taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat
     3241 tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat
     3301 cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc
     3361 taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa
     3421 gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt
     3481 ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg
     3541 tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat
     3601 tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa
     3661 gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa
     3721 tctttcagat atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc
     3781 atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt
     3841 ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt
     3901 agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg
     3961 tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc
     4021 aacccctgcg attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt
     4081 tggcacgcat ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg
     4141 agtgatggcc tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga
     4201 tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat
     4261 gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga
     4321 aaccattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac
     4381 agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt
     4441 aggaactgca cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg
     4501 tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa
     4561 gttctattta agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat
     4621 ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat
     4681 gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta
     4741 ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt
     4801 gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag
     4861 cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg
     4921 agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac
     4981 catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa
     5041 gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat
     5101 gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact
     5161 ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag
     5221 tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg
     5281 taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg
     5341 catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca
     5401 gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga
     5461 agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat
     5521 atcaagataa gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact
     5581 aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta
     5641 gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg
     5701 tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga
     5761 gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca
     5821 ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt
     5881 cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta
     5941 atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc
     6001 cacttccaaa tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg
     6061 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
     6121 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
     6181 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
     6241 ttggagaata acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta
     6301 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
     6361 ctatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac
     6421 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
     6481 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
     6541 ggaaagtccg atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca
     6601 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
     6661 gatacgctta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
     6721 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
     6781 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
     6841 aaatttagtg atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa
     6901 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
     6961 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
     7021 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
     7081 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
     7141 gataggataa acgagaaaga caagataggt aagaaagatg aagaaagagg aagctgtcca
     7201 aatatttagt tttttacatt ccatggttga ctccttttat caggttttgg gaaccatctg
     7261 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
     7321 gttcttcttc aaaagttgat tcttcactaa cttaaatttt tgaggcaaaa cctgtctcaa
     7381 tgaaatactc cgtatttagt ccaagataga cgctatcgct aatagttcct tcgatatctc
     7441 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
     7501 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
     7561 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
     7621 actcattagc tggtttatga tagagttatt ttggtcggcc gatttgttgg atcaccccat
     7681 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
     7741 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
     7801 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
     7861 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
     7921 gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
     7981 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
     8041 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
     8101 tattgatttt tgtatcatcg aagtaaaatt ctccaccttc gatactgttg aaacctgcaa
     8161 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
     8221 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
     8281 cgttaataat ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
     8341 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
     8401 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
     8461 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
     8521 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
     8581 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
     8641 ttaagagttt aactgctgga tcttcataag agagactaac agtcatttct ccatcagcga
     8701 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
     8761 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
     8821 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
     8881 aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
     8941 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
     9001 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
     9061 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
     9121 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
     9181 aagaaccacc aaagataata tcagctacag gaacttcttt ttctgactct agttttttga
     9241 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
     9301 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
     9361 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
     9421 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
     9481 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
     9541 cacattgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
     9601 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat
     9661 tttactattt ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat
     9721 cctgacaaat ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga
     9781 ggtcacaaag gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa
     9841 ggaatgagac atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa
     9901 aattctagag caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg
     9961 aaaagttaag tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga
    10021 aataaactag aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag
    10081 atcttcagga tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata
    10141 tttgttttca ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt
    10201 aaatagagta gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg
    10261 gattcttaaa acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat
    10321 ttgattaaaa accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt
    10381 gtagataaaa tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt
    10441 agtttcaatg gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa
    10501 ttcaaactga gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta
    10561 aaattctttg tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac
    10621 taaggtgaat ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc
    10681 aggattagaa caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat
    10741 acccgggccg tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc
    10801 cataagagtt cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta
    10861 cgaacgaaag gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg
    10921 taaaatgaaa agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt
    10981 taatacatta tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa
    11041 attagagtca aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga
    11101 tgacttaaat gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc
    11161 agtaaaattg gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt
    11221 acttgctgag gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt
    11281 tatagcaaat tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt
    11341 tcagaaggat tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca
    11401 tgtgcatcaa gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa
    11461 agatttaatg cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt
    11521 cctaactgac tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca
    11581 agtctatgaa gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa
    11641 tgctgggata atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa
    11701 taaactgctc tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat
    11761 agcagcaaaa ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa
    11821 tgcaggaatt gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa
    11881 ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga
    11941 taatccaaca attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct
    12001 aattgatgat aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga
    12061 tttaattcac agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag
    12121 tcacatacac gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca
    12181 tggagagtgt acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg
    12241 tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc
    12301 tgtagtcgga attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac
    12361 agaggatgac tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt
    12421 ttttgattca aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc
    12481 tttggaagat ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt
    12541 atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa
    12601 tacaatttta aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga
    12661 gtgaaaatga tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg
    12721 cttatataaa caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt
    12781 gtattctata gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag
    12841 tgaaatgagg aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt
    12901 ttatatgctg gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt
    12961 acatgtgaac ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat
    13021 aatctacaaa caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct
    13081 ctctttgttc attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa
    13141 gaaattatta gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt
    13201 attaacatag aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt
    13261 tctactggta tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca
    13321 gaaatagagg cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca
    13381 ctattgggtc cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt
    13441 gatgttccga tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta
    13501 ttagatttgg ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat
    13561 ggatgttcag aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc
    13621 tctaaaagat gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat
    13681 tatgggacaa ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa
    13741 ttggacagag ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc
    13801 ttgtttttca attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg
    13861 agttctatct gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg
    13921 tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc
    13981 tatcattata ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt
    14041 tattaagatg ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc
    14101 agcatttgta attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa
    14161 tggcggaaca ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac
    14221 tggatctttg tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg
    14281 tgttcatggg caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga
    14341 cgctaataaa gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt
    14401 tactcaacaa tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct
    14461 tgtagttgcc atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc
    14521 agcttttcca gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat
    14581 gaatccagtt atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata
    14641 tggagctatt gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac
    14701 accagctatt ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt
    14761 gatattagcg atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc
    14821 ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca
    14881 tttgtgctaa aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa
    14941 aaatcggtat tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat
    15001 ggtaaataca gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga
    15061 aaggatgaac aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag
    15121 agcagttcta gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg
    15181 tgcatatatg ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat
    15241 gattgcggga aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct
    15301 agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat
    15361 tacagaagaa acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt
    15421 acgtgctaga gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt
    15481 cttcggtatg gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa
    15541 acttttgcaa tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct
    15601 agatttaaca gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt
    15661 aatcgatgct attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga
    15721 aaatgcaaat cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt
    15781 cccatatgaa ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg
    15841 tattttacaa attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat
    15901 gtatccatat atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga
    15961 acgtctgaca aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca
    16021 tacattttct tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg
    16081 agataagaag gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac
    16141 ccatctaccg caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat
    16201 gaatgagtgt attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga
    16261 gattattatt ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag
    16321 tgccattgga tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat
    16381 gagttatatg aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc
    16441 ttcgggtaaa cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga
    16501 attagaaaat gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga
    16561 aaattctatt gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac
    16621 tgatgattgt attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat
    16681 atcaggattg caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt
    16741 ggtgtttgag gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta
    16801 tgccggagaa gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg
    16861 taatgatgat gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga
    16921 aattgctaaa tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc
    16981 aggaacatct tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga
    17041 tggacgcaac gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca
    17101 acacggccct acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg
    17161 tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt
    17221 aaaactaatt gctttgttac gaacattctt taatcgttta catgggtacc atattcaata
    17281 caatgttgtt tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga
    17341 cttaattgtt cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca
    17401 agatgacatt ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga
    17461 atttatgctt gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct
    17521 agctggggta acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga
    17581 acgaatcaaa gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat
    17641 ttctcaagat tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga
    17701 tgatatattt atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa
    17761 aaaagagggc taccatatca ctgcaacagc tatttataca gttattcagg gattattagc
    17821 tatcgaagta ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat
    17881 tgattcaaat tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag
    17941 taagatttta gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg
    18001 tgcgcatgct gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat
    18061 ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat
    18121 ttagatagag aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg
    18181 gaaaatgcct tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta
    18241 ttatgcgatc agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg
    18301 tatggtttcc atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat
    18361 cgagttgttg ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga
    18421 aagacgattg atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct
    18481 ccaacaattg catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa
    18541 ggtgcatttg atcattatct attttattct aaaaatccag atttagtttt ggttgataca
    18601 aaagttattt cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca
    18661 acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag
    18721 caaacattgg ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt
    18781 ttacaggcta tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt
    18841 gaagctaata ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat
    18901 gcaattcata atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa
    18961 aaagtagctt atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt
    19021 gataagtata ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat
    19081 ttggatcaag ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt
    19141 gagacaattc atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc
    19201 gctgtagatg cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta
    19261 gtcttttatt gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc
    19321 gattgggaaa gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag
    19381 attcagtcca ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat
    19441 tgtgaataca ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct
    19501 atacgagata agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt
    19561 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    19621 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    19681 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    19741 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    19801 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    19861 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    19921 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    19981 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    20041 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    20101 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    20161 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg
    20221 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    20281 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    20341 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    20401 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    20461 tgttttggct cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc
    20521 agtagcagac tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc
    20581 caaagaaaaa actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga
    20641 aattccaatc tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc
    20701 tgtgcctgcc cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    20761 cgaagtactt gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt
    20821 taattcagac ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg
    20881 gttggaagaa aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt
    20941 tagccgtcaa cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc
    21001 aacagctgtc cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc
    21061 ctcaggtact ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga
    21121 agatggtgtc aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg
    21181 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct
    21241 caaacaatgg ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt
    21301 gctttacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    21361 accattccaa aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg
    21421 tggggctctt gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga
    21481 aacaggggaa gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt
    21541 caacccagac gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt
    21601 catgggacca ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa
    21661 gttccttgac cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg
    21721 cgctcttgac aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct
    21781 caaattcaac acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    21841 caagctctat gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca
    21901 cttggcagaa gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac
    21961 ttggccaaca tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat
    22021 caaaggtaaa gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca
    22081 agaaattgct ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa
    22141 agtgattagt gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct
    22201 gatttccaac ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt
    22261 tgtgaaataa ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat
    22321 gaaagtatgg tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta
    22381 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg
    22441 aactgccttc tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg
    22501 aaaagcatgc ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga
    22561 cctacctttt tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga
    22621 tgttggctcg taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt
    22681 tgggatcttt ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag
    22741 tcactttttc tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag
    22801 ctcgctatgt ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa
    22861 atctgccatc cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc
    22921 aggcagtggt ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg
    22981 actggcctca agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa
    23041 atggacagca gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa
    23101 aaagcaagaa attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac
    23161 aaattatacc catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta
    23221 tctggcactt gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc
    23281 atcagtattg gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag
    23341 tgccttgatg aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac
    23401 agaagagaca gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac
    23461 ctataattgt atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct
    23521 taagcaaaat ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    23581 tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc
    23641 aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg
    23701 atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat
    23761 ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt
    23821 gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg
    23881 tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg
    23941 aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa
    24001 gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac
    24061 tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct
    24121 tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac
    24181 cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    24241 tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt
    24301 cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag
    24361 tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc
    24421 tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat
    24481 tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg
    24541 tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca
    24601 gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga
    24661 gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt
    24721 gctttatagt gctatggagg acttctacat agatattatg attggggctg gtgagggtag
    24781 tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg
    24841 tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc
    24901 ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac
    24961 tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg
    25021 tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat
    25081 tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga
    25141 tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac
    25201 tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt
    25261 gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata
    25321 tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag
    25381 aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt
    25441 ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt
    25501 ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa
    25561 ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa
    25621 atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg
    25681 ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag
    25741 attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa
    25801 ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga
    25861 aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc
    25921 tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt
    25981 ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa
    26041 aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt
    26101 ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga
    26161 taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga
    26221 tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg
    26281 catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac
    26341 ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat
    26401 gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa
    26461 gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa
    26521 ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg
    26581 tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa
    26641 aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt
    26701 gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag
    26761 caattttctt ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc
    26821 tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg
    26881 atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca
    26941 gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata
    27001 gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag
    27061 accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg
    27121 gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt
    27181 tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc
    27241 cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt
    27301 gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc
    27361 tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa
    27421 acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg
    27481 atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt
    27541 ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt
    27601 ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat
    27661 agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga
    27721 ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg
    27781 cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc
    27841 atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt
    27901 cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa
    27961 atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc
    28021 aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat
    28081 tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg
    28141 gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat
    28201 gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg
    28261 aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc
    28321 agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga
    28381 gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc
    28441 ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact
    28501 atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt
    28561 taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt
    28621 tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc
    28681 caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct
    28741 gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg
    28801 atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct caatatccta
    28861 gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga
    28921 gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt
    28981 tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa
    29041 atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc
    29101 caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct
    29161 aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc
    29221 cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt
    29281 tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc
    29341 tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat
    29401 caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt
    29461 gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt
    29521 tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag
    29581 gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt
    29641 acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt
    29701 gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc
    29761 tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg
    29821 gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt
    29881 gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa
    29941 caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt
    30001 ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac
    30061 gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca
    30121 gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat
    30181 gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat
    30241 tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga
    30301 caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact
    30361 cgctactcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc
    30421 atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac
    30481 gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat
    30541 ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa
    30601 gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc
    30661 ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt
    30721 cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc
    30781 aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc
    30841 ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt
    30901 taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta
    30961 agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt
    31021 gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat
    31081 cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg
    31141 gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca
    31201 cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag
    31261 gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat
    31321 ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc
    31381 tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt
    31441 acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca
    31501 cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc
    31561 cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac
    31621 ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg
    31681 gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag
    31741 ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa
    31801 ctcattcatg ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt
    31861 atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag
    31921 ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa
    31981 gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg
    32041 actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa
    32101 gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa
    32161 gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc
    32221 aacagctata aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt
    32281 ctgaagaaat caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga
    32341 ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta
    32401 taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta
    32461 taaaagatga attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat
    32521 atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc
    32581 aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg
    32641 gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag
    32701 ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa
    32761 cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg
    32821 gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag
    32881 ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc
    32941 tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg
    33001 ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt
    33061 tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg
    33121 aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg
    33181 tggaagttca agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg
    33241 acttgtcaga tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc
    33301 aaccaactgt tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg
    33361 tagacccaga tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg
    33421 gaacatctta ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac
    33481 cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac
    33541 cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca
    33601 aggctaatga aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct
    33661 cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa
    33721 ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag
    33781 caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc
    33841 agtctattga atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc
    33901 ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg
    33961 aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag
    34021 aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt
    34081 cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg
    34141 ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta
    34201 cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt
    34261 actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag
    34321 taacggtaga ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg
    34381 ttgcttgtac tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt
    34441 cgccttgccg taggtatggt tactga
//
LOCUS       DAVBED010000017        34347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBED010000017 DAVBED010000000
VERSION     DAVBED010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.017"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQ547_000840"
     CDS             <1..4786
                     /locus_tag="VQ547_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2542711.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQ547_000841"
     CDS             complement(5023..5571)
                     /locus_tag="VQ547_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2542712.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQ547_000842"
     CDS             5892..6380
                     /locus_tag="VQ547_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2542713.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQ547_000843"
     CDS             6377..7564
                     /locus_tag="VQ547_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2542714.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQ547_000844"
     CDS             7557..7922
                     /locus_tag="VQ547_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2542715.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQ547_000845"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQ547_000845"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2542716.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQ547_000846"
     CDS             9437..9727
                     /locus_tag="VQ547_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2542717.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ547_000847"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ547_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2542718.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQ547_000848"
     CDS             10241..10480
                     /locus_tag="VQ547_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2542719.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQ547_000849"
     CDS             10775..12175
                     /locus_tag="VQ547_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2542720.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQ547_000850"
     CDS             12177..12536
                     /locus_tag="VQ547_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2542721.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQ547_000851"
     CDS             12590..13339
                     /locus_tag="VQ547_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2542722.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQ547_000852"
     CDS             13329..13628
                     /locus_tag="VQ547_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2542723.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQ547_000853"
     CDS             13699..14634
                     /locus_tag="VQ547_000853"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2542724.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQ547_000854"
     CDS             14721..15233
                     /locus_tag="VQ547_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2542725.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQ547_000855"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQ547_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQ547_000856"
     CDS             15966..16160
                     /locus_tag="VQ547_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2542726.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQ547_000857"
     CDS             complement(16206..17651)
                     /locus_tag="VQ547_000857"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2542727.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQ547_000858"
     CDS             17757..19379
                     /locus_tag="VQ547_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2542728.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQ547_000859"
     CDS             19583..21541
                     /locus_tag="VQ547_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542729.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQ547_000860"
     CDS             21713..22648
                     /locus_tag="VQ547_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542730.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQ547_000861"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQ547_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQ547_000862"
     CDS             23483..24577
                     /locus_tag="VQ547_000862"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2542731.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQ547_000863"
     CDS             24585..25751
                     /locus_tag="VQ547_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2542732.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQ547_000864"
     CDS             25844..28942
                     /locus_tag="VQ547_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2542733.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQ547_000865"
     CDS             28990..29607
                     /locus_tag="VQ547_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2542734.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQ547_000866"
     CDS             29617..30951
                     /locus_tag="VQ547_000866"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2542735.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQ547_000867"
     CDS             30961..31425
                     /locus_tag="VQ547_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542736.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQ547_000868"
     CDS             31422..31916
                     /locus_tag="VQ547_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542737.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQ547_000869"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQ547_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2542738.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQ547_000870"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQ547_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2542739.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBED010000018        33324 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBED010000018 DAVBED010000000
VERSION     DAVBED010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.018"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQ547_000871"
     CDS             <1..327
                     /locus_tag="VQ547_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2542740.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQ547_000872"
     CDS             749..979
                     /locus_tag="VQ547_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2542741.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQ547_000873"
     CDS             1383..2096
                     /locus_tag="VQ547_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2542742.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQ547_000874"
     CDS             2154..2756
                     /locus_tag="VQ547_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542743.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQ547_000875"
     CDS             2892..3545
                     /locus_tag="VQ547_000875"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2542744.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQ547_000876"
     CDS             3555..4019
                     /locus_tag="VQ547_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2542745.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQ547_000877"
     CDS             4032..5300
                     /locus_tag="VQ547_000877"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2542746.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQ547_000878"
     CDS             5314..5574
                     /locus_tag="VQ547_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542747.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ547_000879"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ547_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2542748.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQ547_000880"
     CDS             7100..8068
                     /locus_tag="VQ547_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2542749.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQ547_000881"
     CDS             8084..9076
                     /locus_tag="VQ547_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2542750.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQ547_000882"
     CDS             9294..10337
                     /locus_tag="VQ547_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2542751.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ547_000883"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ547_000883"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2542752.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQ547_000884"
     CDS             12150..13139
                     /locus_tag="VQ547_000884"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2542753.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ547_000885"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ547_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2542754.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQ547_000886"
     CDS             complement(14860..16410)
                     /locus_tag="VQ547_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2542755.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQ547_000887"
     CDS             complement(16426..17205)
                     /locus_tag="VQ547_000887"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2542756.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ547_000888"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ547_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2542757.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQ547_000889"
     CDS             complement(18250..18426)
                     /locus_tag="VQ547_000889"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2542758.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ547_000890"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ547_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2542759.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQ547_000891"
     CDS             complement(24578..25756)
                     /locus_tag="VQ547_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542760.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ547_000892"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ547_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2542761.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ547_000893"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ547_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2542762.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQ547_000894"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQ547_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6539 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBED010000019        33044 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBED010000019 DAVBED010000000
VERSION     DAVBED010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.019"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(550..1239)
                     /gene="rplA"
                     /locus_tag="VQ547_000895"
     CDS             complement(550..1239)
                     /gene="rplA"
                     /locus_tag="VQ547_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2542763.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1446..1871)
                     /gene="rplK"
                     /locus_tag="VQ547_000896"
     CDS             complement(1446..1871)
                     /gene="rplK"
                     /locus_tag="VQ547_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2542764.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1994..2710)
                     /locus_tag="VQ547_000897"
     CDS             complement(1994..2710)
                     /locus_tag="VQ547_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2542765.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2713..3183)
                     /locus_tag="VQ547_000898"
     CDS             complement(2713..3183)
                     /locus_tag="VQ547_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2542766.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(3185..4222)
                     /locus_tag="VQ547_000899"
     CDS             complement(3185..4222)
                     /locus_tag="VQ547_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2542767.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4320..5645)
                     /gene="brnQ"
                     /locus_tag="VQ547_000900"
     CDS             complement(4320..5645)
                     /gene="brnQ"
                     /locus_tag="VQ547_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2542768.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5816..5908)
                     /locus_tag="VQ547_000901"
     CDS             complement(5816..5908)
                     /locus_tag="VQ547_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2542769.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5951..6103)
                     /locus_tag="VQ547_000902"
     CDS             complement(5951..6103)
                     /locus_tag="VQ547_000902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2542770.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6263..6841)
                     /locus_tag="VQ547_000903"
     CDS             complement(6263..6841)
                     /locus_tag="VQ547_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2542771.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6895..8295)
                     /gene="pepV"
                     /locus_tag="VQ547_000904"
     CDS             complement(6895..8295)
                     /gene="pepV"
                     /locus_tag="VQ547_000904"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2542772.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8308..8913)
                     /locus_tag="VQ547_000905"
     CDS             complement(8308..8913)
                     /locus_tag="VQ547_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2542773.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9084..9884
                     /locus_tag="VQ547_000906"
     CDS             9084..9884
                     /locus_tag="VQ547_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2542774.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10066..10899)
                     /locus_tag="VQ547_000907"
     CDS             complement(10066..10899)
                     /locus_tag="VQ547_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2542775.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10889..12736)
                     /gene="uvrC"
                     /locus_tag="VQ547_000908"
     CDS             complement(10889..12736)
                     /gene="uvrC"
                     /locus_tag="VQ547_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2542776.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12776..13477)
                     /locus_tag="VQ547_000909"
     CDS             complement(12776..13477)
                     /locus_tag="VQ547_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2542777.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13556..14788)
                     /gene="murN"
                     /locus_tag="VQ547_000910"
     CDS             complement(13556..14788)
                     /gene="murN"
                     /locus_tag="VQ547_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2542778.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14793..16013)
                     /gene="murM"
                     /locus_tag="VQ547_000911"
     CDS             complement(14793..16013)
                     /gene="murM"
                     /locus_tag="VQ547_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2542779.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16125..16904)
                     /locus_tag="VQ547_000912"
     CDS             complement(16125..16904)
                     /locus_tag="VQ547_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2542780.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16973..18634)
                     /locus_tag="VQ547_000913"
     CDS             complement(16973..18634)
                     /locus_tag="VQ547_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2542781.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18809..21031)
                     /gene="recJ"
                     /locus_tag="VQ547_000914"
     CDS             complement(18809..21031)
                     /gene="recJ"
                     /locus_tag="VQ547_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2542782.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21308..22066
                     /locus_tag="VQ547_000915"
                     /pseudo
     CDS             21308..22066
                     /locus_tag="VQ547_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22106..22870
                     /locus_tag="VQ547_000916"
     CDS             22106..22870
                     /locus_tag="VQ547_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2542783.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22883..23560
                     /locus_tag="VQ547_000917"
     CDS             22883..23560
                     /locus_tag="VQ547_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2542784.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23570..24229
                     /locus_tag="VQ547_000918"
     CDS             23570..24229
                     /locus_tag="VQ547_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2542785.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24524..25714
                     /locus_tag="VQ547_000919"
     CDS             24524..25714
                     /locus_tag="VQ547_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2542786.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26035..26916)
                     /locus_tag="VQ547_000920"
     CDS             complement(26035..26916)
                     /locus_tag="VQ547_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2542787.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27057..28385)
                     /gene="vncS"
                     /locus_tag="VQ547_000921"
     CDS             complement(27057..28385)
                     /gene="vncS"
                     /locus_tag="VQ547_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2542788.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28382..29038)
                     /gene="vncR"
                     /locus_tag="VQ547_000922"
     CDS             complement(28382..29038)
                     /gene="vncR"
                     /locus_tag="VQ547_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2542789.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29087..29170)
                     /gene="pep27"
                     /locus_tag="VQ547_000923"
     CDS             complement(29087..29170)
                     /gene="pep27"
                     /locus_tag="VQ547_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2542790.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29350..30729)
                     /gene="vex3"
                     /locus_tag="VQ547_000924"
     CDS             complement(29350..30729)
                     /gene="vex3"
                     /locus_tag="VQ547_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2542791.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30781..31428)
                     /gene="vex2"
                     /locus_tag="VQ547_000925"
     CDS             complement(30781..31428)
                     /gene="vex2"
                     /locus_tag="VQ547_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2542792.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31441..32718)
                     /locus_tag="VQ547_000926"
     CDS             complement(31441..32718)
                     /locus_tag="VQ547_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542793.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9329 a         7572 c         6145 g         9998 t
ORIGIN      
        1 aaatcgagta ggggataatc tctagcccct ctcacaccac cgtacgtgcc gttcggcata
       61 cggcggttca actaactgtt aacgcatgtc gttcaaggta ataatccaaa cacgaaacca
      121 gtccacgttt ttcaaggact ggttttgata tagcacgttt aagtaccgac ttctgagcta
      181 ctatagtaga ttgaaactag aatagtacat ctcttcttct aaaacattgt tagaaatcga
      241 tttggctgcc ctgatcgatt cgtcctactc ttatttcatt ttactataat tgatagtggt
      301 cgccccagcc agatacctta tccgctatat aggccttatt atcatgttcc tgttcgtaga
      361 gccacgattt cgctatccct tcctctgacg attcttattt cctgcgtcag acttgggaat
      421 cgctattggg ttcaccggta gcaggtgccc accgaggact tacacctcag atatacgaca
      481 tgcccgtcgt acatcaaaaa aagttgagac atagcgtctt caactttttt acattacttt
      541 aactactgat taaagtgagt ttacgtcaac tttgatacca acaccttgag tagttgtgat
      601 agtcaagttt gttacgtaag ttcctttagc tgtagctggt tttgcttttt ggattgtttc
      661 gttgaaagct ttaaagtttt caaccaattt ttcagcttca aatgatactt taccgatgat
      721 tgcttgaacg ttacctgcac ggtcagcacg gtaagtgatt ttaccacctt tagactcttc
      781 aactgcttta gcaacatcca ttgttacagt accagtttta gggtttggca tcaagttacg
      841 tggtccaagg acacgtccaa gacgtccaac aagacccatc atatcaggtg tagcgataac
      901 tacgtcgaag tccaaccaac cgtcgttgat tttagcaaca aggtcatctt caccaacaaa
      961 gtctgcacca gcagcttttg cttcttcagc ttttgcacca cgtgcgaaaa caagaacgcg
     1021 tgaagtttta ccagtaccgt ttggcaatac cattgctcca cggatttgtt gatcagcttt
     1081 tttaacgtcg atgttcaagt tgtaagcaac ttctacagtt gcgtcaaatt ttgcaaagtt
     1141 tgtttctttt gcaagtgcta cagcttcttc tacgctgtat gcttttgtgc tgtcgatttt
     1201 ctcaagagca gcacgaagtt gtttgctttt tttagccatt ttctattctc cttgtaagtg
     1261 gttcaatcga ttttcatctc ccacgtcact tctcgaaatg atgaagtctt gcgggttttc
     1321 agtctattag attcttttcc tacggcctta agctcccttg ctgtacccaa gtacaagcat
     1381 cagtcacttg cctagtatga aaagcaacta atagactgct gtgagatttt ctactgtgtt
     1441 attgattagt caataacagt gaatcccata gaacgagcag taccttcgat catacgcact
     1501 gcagactcta cgtttgctgc gttcaaatct ggcatcttag tttctgcaat ttcttgtact
     1561 tgtgcacgag taactgtagc aactttagtt ttattaggtg tacctgatcc tttttcaaca
     1621 cctgcagctt ttttcaaaag aacagcagct ggtggtgttt tcgtaacgaa agtaaatgat
     1681 ttatcttcgt aaactgagat aacaactgga atgatcatac cagcttggtc agctgtacga
     1741 gcgttgaact cttttgtgaa tcccatgatg ttgataccag cttgaccaag agcaggtcca
     1801 accggtggag ctggtgtagc tttaccagca gggatttgca attttacaag tttttcgact
     1861 tttttagcca tttttaaatc ctcctttgtg gttttggcgg taattagaga tttttacctc
     1921 ccacaagtat gtttttcaca tacccatcta ttatacacta tttatctgga attgcaagag
     1981 aaaagtttat tttttaatcg acgtaatctc caccttcaaa gccgaaatac tcttccaaac
     2041 tgaggccact agctgcaatc tctttagcct cttttccgac ataacgaagg tgccattcct
     2101 cagccatata gcctgtttcc ttttccttac ctttgagata acgtacaaca aagccataat
     2161 cagccgcatg atccaagagc cattgggccg ctttttcttc tgtcaccaaa tcaccatttg
     2221 tcccaatcac atcaaaggct aaacctgtct ggtgctcgct atagccagga cgggcagaat
     2281 aacggtcggc agcttctttc ccatcttgat tgacataatc ttgatagagc ttggtctgag
     2341 tttcataact tctaaagcca ctgtaatgat cgctaatggg gaaacctgcc tcttgcatag
     2401 ctttgatgag cttgaccaac tcagccttgg ctgttggatt ttcccctgga ttgtagtctt
     2461 ttgacaatgg atagtgtttg ttggctacga tgatttcatc gtatttccct tgaatgctgt
     2521 aatagtctcc tttgttaacc acttctgctt ttttctgggc agctccttga gacttacttc
     2581 ctactgttcc atcagcttta gcagtttgct ctgtcttagc tgctccatct tcattttttg
     2641 ctttttcttg tgaacaagct gctagactca aggctagcaa ggctgtcaag acaaggtatc
     2701 tttttttcat ctttactcct ttatttctaa tagtttatct acttctgatg ataaacgttc
     2761 gactaatctt ttaatctcat caggttttga ttggcagatt tctgctgtca tttcttcaaa
     2821 gggaatccac catactggac cacgtccatt gaggccataa ccattcatat cacctcttcg
     2881 tctaggaaac agatgccaat ggagatgagc atcgccattt cctagtagtt cgatattcat
     2941 tttctcagca gcaaaggcct tggcaactgc ctcttggacc acactcattt cttctagaaa
     3001 acgtattcta gttttctttt ctaaatgatg caattcgctg acatgttcct tggctagaaa
     3061 gagactatag cctgcaaaat actggtggtc tccaatcaca agatagcctg tttccaactc
     3121 tttgacaaaa tagggatttt ctcccttctt gatgagctca attctctggc aaatcaaaca
     3181 catattagtc taccaatgca ctcttaagat aggcatcgac cattcgttct gttgcgacca
     3241 ccgagtcaat atgagtgcgc tcataagaat gactagactc gatacccgca ccaagaaggg
     3301 catgcttgac ctctgcccct gcagacatag ccgctgaagc atccgaacca taaaatggat
     3361 agatgtccag cttaaaagga atatcttgct ctttagccaa ggcaaccaag tgttgacgga
     3421 agtcatagtg ataaggacct gaggcatcct tgacacagat agatactgtg tactcatttg
     3481 tctgctggtc atctcccata gctcccatat ccacagccag atattctact acctgagcag
     3541 gaatgttaga attagcacca tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg
     3601 ttactggcaa ttcaatcttc tctttcttat aaatacgaag caggttgagc aacatcgctg
     3661 cgctgacctt atcatccaaa tgacgagact tgataaaacc tgtatcagtc acaacagttc
     3721 gtggatcgaa gctgataaaa tcaccgacct caatcccaag agcacgagtt tctttttcat
     3781 tgcttacttt tacatccaaa cgcacttcca tattgtcctg cgtgcgttct gcagttcctg
     3841 catccttgta gacatggcaa gaagtttggt ggatgaggat ggttcctaat accttttgac
     3901 ctgtgctagc cacatgaacg gtacagtttt caccttcaat catgttccaa ggaaaaccac
     3961 cgatacggtc caatttaaga cgaccatctg gtttgacagc acgaacaata gcacccagtg
     4021 tgtccacatg ggcagtcaca tagcgatgtt gctcatcatt ttgacctttg atggtcacat
     4081 tgacaccacc cttggctgtg cgaactggct ggtaaccaaa accttctaga gtcttgacta
     4141 aataattcga aatttcacga gtgaagcccg ttggcgatgc gatggctgtc agttctttga
     4201 tatattctac tgtttgattc atttcttcac ctctttcgct acctattata acacatttat
     4261 catcggataa aaaaagaaaa tcactcctgt agacttggct acaaaagtga tttaagtgat
     4321 tattccattt caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt
     4381 ccaacaatgg ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca
     4441 agatttgcaa gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact
     4501 gtaaccacag caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca
     4561 atgacaatca taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag
     4621 tacttgataa tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct
     4681 gtcgcataaa ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac
     4741 acaatcaaac caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt
     4801 tgagctgttg agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt
     4861 ccacccttca tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccgatg
     4921 taaagagcgc tgaaggcaag ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat
     4981 tctttcttac ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc
     5041 actgaggcaa gggcgtccaa ggtattataa ccttctagga aacctgtacc aaaggcagaa
     5101 gcttgataag cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga
     5161 acgaccaaga taacaatcaa aattgcaaag actggcgtta aaatacgtcc aatgcggtct
     5221 aagatttttg atggattaag cgaaatcaaa taggctgccg caaaatacag aaccgtaaat
     5281 acaatcaagc caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa
     5341 gctgttgtag cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag
     5401 aggtaaagag tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta
     5461 ggatttagcg ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa
     5521 cctgcgatgg caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc
     5581 aagttccccg caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta
     5641 gccataaaaa tctccttcat atttataaaa tactgatcta gtataccacg attaggagtc
     5701 tgaaaaaagc atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta
     5761 tctaaaaata aaactctcct acccagtcca caccaagtag gagaaatgca aaattttaaa
     5821 gttcttcaaa ggctaacatg ccaccctgga cattgataac attataacct tgttctaata
     5881 ggaattggca agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat
     5941 ctttgtccaa ttaatcataa ctatcagcca attgactaag cggtaggttg tgggcacctt
     6001 ctaaatgaag agctgcaaac tcatccactt ctctcacatc cactagagaa agctggtcgt
     6061 tttggtaaag ctggtaaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac
     6121 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt
     6181 cgtcagtttt atctgcaact tcaaagctgt actttgagca gcctacgact agcttcctag
     6241 tttgctcttt gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca
     6301 ctacttctgc ctcaaaccaa ggatttttgg ccatccagat ttgatttcgt ggtgatgggt
     6361 gaactagcgg aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct
     6421 tcccactgat tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta
     6481 actgaatatc aggcaattcc tgtaagagct gcggatgcca tttttctgca aaacctgtac
     6541 aaggcggaag atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag
     6601 caaaataacc tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaaacggt
     6661 caccactttt atctttccag taaaggcctg cttcttgagt tttaagtccc ggagcctgac
     6721 cgatgatatt gatgcgagca gtttttggcg ctgcaaagag aggctcaatg ccacgctctg
     6781 tatagctggc attctgcgaa tccgccatga tagcctgttt gattctttcg atttgagaca
     6841 tctactttcc ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt
     6901 gatcaattcg taaatagctt cggcataaat tgctgctgct cggaagagat cgtccaaggc
     6961 aataaattca ttggcttggt gcatggtatc aattgagtct gggaacatag caccataggc
     7021 aactccgcgc tctaacaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttt
     7081 aaggcctgtt tgtttttcat agacattcaa caaggtttgc acaagtggat cttccattgg
     7141 cacatagtga ggggtatgac catgttctga tagactgaca gaagcaactg gcaagttttc
     7201 taggattgac ttgatttgtt ctggacttgt tccttttgga tagcggatgt taagggcaat
     7261 ggtattatca gcacttgttt catcgaagcg gaagacgccg gcattcatag aaagagcacc
     7321 catcttttca tccacatgag caatcttgag attttcaccc tcatgatcgt tcaagagaat
     7381 tttacctgcg atgtcaaggt agtctttggc tggaccagca aagccaaact ggctgaggaa
     7441 gagggcaagg taagttgcgc cattgacacc tgaagcaggc atagcaccgt gggctgattt
     7501 accaatgatc gtcaccttgt attggccagc ttcttcttgg agttctcctc taagtttgtg
     7561 ttctgcaaca aaggcatcta gtttagcttg caagtctgtc aagtcacctg aaacgactgc
     7621 tgttgctgat tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc
     7681 tgcacctgta ttttcacctg caaagtggag gtattccgtg atgtttcctt tttcaccatt
     7741 gatgattgga aattcagcat ctggtgagaa accaaagtct ggcttggcga gtcctacgtg
     7801 ctcgaagtag tagtccatat ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg
     7861 aactttctta gaagttggaa ggcccaattc tttgatgatt ttcaaaccat agtagcaagc
     7921 tgttgtaggt cccttgtcat ctgaagcacc acgcgcataa aggcgaccat ctttgatagt
     7981 tggtgtgtaa gggtctgtgt cccaaccgct accagctgga accacgtcca tatgggcaaa
     8041 gattccgaga acttcttctc catcaccaaa ctcaaaatgt cctgcatagt tatcaacatt
     8101 tttagttgga taaccatcac ggtctgcgat ttcaaggaat ttttccaagg cttttactgg
     8161 accaggtcca aatggatgtt gggcatcagc cttgctatca tcacgttctg agttgatttc
     8221 caaaaggcta aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa
     8281 atcaattgct atcatttttt cttcttccta tcttttttcg atgatttcat ctactggcaa
     8341 gcggtagctt ggttccaatt tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg
     8401 gaaacggtct tcaatttcca aaacctcatt gacttttgat ttgtcaaaac caaggataat
     8461 attggaacca attccttggt ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc
     8521 attgagtgct aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa
     8581 atttttcatg aagtattgaa gttgttcttc tgagaaattg ttagcaccac caactcgggc
     8641 aatcttacga gcgcgtttgg caaggtctgt atctgtaaat agggcaatgg ttacaggtgc
     8701 tgatgatacc tgctcaaagt ttgaaccata agccaacttt gccagttcag catttttctc
     8761 acgaacaact acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat
     8821 ttcgatagcc gtacgcacat cttttagatc aacaggctta tcagtgaaat gcttggtcgc
     8881 atgacgtttt ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg
     8941 cttccattct accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta
     9001 tcacagacat aaaagatata tattggttta tcaggaaagt ttctgataaa ctagcaagta
     9061 ctttacattt gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat
     9121 ttttggttgc ctgtgggaat caagctacac ccaaagagac tagcgctcaa aagacaatcg
     9181 tccttgctac agctggcgac gtgccaccat ttgactacga agataaaggc aatctgacag
     9241 gcttcgatat cgaagttcta aaggcagtag atgaaaaact cagcgactac gagattcaat
     9301 ttcaaagaac cgcctgggaa agtatcttcc caggacttga ttctggtcac tatcaggctg
     9361 cggccaataa tttgagttac acaaaagagc gtgctgaaaa atacctttac tcgcttccga
     9421 tttccaacaa tcccctcgtc cttgtcagca acaagaaaaa tcctttgact tctcttgacc
     9481 agatcgctgg taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata
     9541 actggaatca gaaacacact gataatcccg ctacaattaa tttttctggt gaggatattg
     9601 gtaaacgaat cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat
     9661 ccgttcaaaa gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttctg
     9721 cagatagccc cagcaattat atcattttct caagcgacca aaaagagttt aaagagcaat
     9781 ttgataaagc actcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct
     9841 atctaggtgg ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct
     9901 cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct
     9961 agcttcctag tttgctcttt gattttcatt gagtataaga tatactaaaa gcgattggac
    10021 cagccaatcg cttttttagt ttgcattggc tattttagga aactcttaca aaaaatcaaa
    10081 aaaattcttc acatcctcta catacccatg cttttctatt aagctggcta aaagttccag
    10141 attgtgcccc tgatagttat cgtcacgacg cagttcttca tacatttcaa taaagggaag
    10201 ccccttggac ttggccaatt ctaactcagc ctcgtaatca taagcaactt tacgaaattg
    10261 gatattgacc aattccccat cttcaacttc tatcacggca tactgggcac ggtgattttt
    10321 taacgcctcc caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc
    10381 ttgacttcca taacgaagca actgcttgtg aacatgacca taaactgcca cgtccgtttc
    10441 cgcatctagc agttggtcaa atttctctgt atcattctca actagcaagt caccaccata
    10501 gttcttattt ggcaaattat gagagataga aaagcgcagt ccagcaattt ctttcttttc
    10561 cagcaaaggc aagcttcgta gccagacagt cgttgcagga tccattcgct ccatcaaaaa
    10621 ctgagtcatt cgcatgagct ggatttcctg tgggtcttct aagccatatt gcccatctaa
    10681 agcctcaagg acacaatcat tccaattgcc tcgaacactt gccgtgatag gaagttcctt
    10741 taacagagcg accaagtcat ttgcacctga accagggagg aaaatgtctc ccatgagcca
    10801 atattcactg gctccttgag ttttagcatc tgcaatcact gcttctagcg ccgtcgcatt
    10861 gccatgaata tctgataaaa ttgcgatttt atggtttatt gtggtttcct tccgtttggt
    10921 aatctactct ttcttccgcc acttgaagca agatttctgt ttcctgcggg ttcaactttc
    10981 tttgcacagc ctctgctact gctcttggta ctccaacttc gacaatctca tccacactgg
    11041 cttccttgat tttggtcaga gacttgaagt gcctcatgag attttgcttg cgtttaggtc
    11101 ccagaccatc aatcccatcc aattgagatg agaaagaatt tttggagcgc agttggcggt
    11161 ggaaggtaat ggcaaagcgg tggacctcat cttgaatgcg ttggaggagg aaaaattcct
    11221 gagaattgcg agacaagtcc accacttcca gcggatctcc aaagagcaat tcatgggttt
    11281 ggtgcttatc attcttttgc agacctgcaa ttggaatatc caagcccagt tcttcttgga
    11341 tgacttgctt agcaatattg acttgacctt gccccccatc aatcacaatc aaatctggag
    11401 gagtcaaagc ctcacgctgt actcgaccat agcgtcttcg aatgacttct ctcatactag
    11461 catagtcgtc cggcccaaca acggttttta tcttgtactt acggtaatct tttttacttg
    11521 gcctgccgtt aacaaagacc accatggctg aaacaggact ggtccccatg atgttggagt
    11581 tatcgaagga ctcgatgcga actggagtcg gaatttggag caaacgtcct agattttcaa
    11641 tagctccttg ggtcttttcg actgattttt ctagcaggtt aaatttctgc tccagactaa
    11701 cacgtgcatt ttttatggct agattgacca gctgtttttt ctctccacgt tggggtttga
    11761 gaatcttggt atccaccaaa gccttgacag cttcttcgtc aatatcctgc ggaatcagta
    11821 cctcattggg aactaggtga gatttttctt gatagaattg tcccacatag gtcaagaaat
    11881 cctcatctgg atcattgaag taggggaaga gattgacatc gcgctcgatg agcttgccct
    11941 gacgaacaaa gaaaacctgc acacacatcc agcccttatc cacatagtag ccaaagacat
    12001 cgcgattttg gagatcctta gccatgaccc gttgcttggt tcgaagcgtt ccaatagcct
    12061 gaatcaggtc acggtattcc gccgcacgtt caaactccat actttgtgct gctactgcca
    12121 ttttactctt gagatcatcg atgattttgt catcctgacc tttcagaaaa tcagacacct
    12181 cctgagccat agacttgaaa taagcctcat ccttcttaca gatggtgtgg gccatacact
    12241 ggccgatatg gtaataaaaa cagaccttag agggcgggtt ggtacatttt cgaaaaggga
    12301 aaatcctatc tagaagtcgc ttgatttcat tggctgcccc cacatctgga taagggccaa
    12361 aataaagacc accgtccttt ttgacctgac gagtaatgat aagccgtgga tagcgctcat
    12421 tggtgatttt gatgaaagga taggacttgt catccttgag catgatattg tacttgggct
    12481 tattttcctt gatcaagttg atttccagca gaagcgcctc aatattggac tcagtgacga
    12541 taaattcaaa atccacaatt tcagacacca gagcctctgt cttggtatca tgaattccac
    12601 gaaaatagga ccgtactcga ttacgcagat ttttagcctt tcctacatag ataatggtgc
    12661 catttttatc cttatgaatg tagcaaccag ggctggtcgg caagagctct agttttgatt
    12721 taatcaagtt gttcatagtt ccattatagc aaaaaaagta gggaaagata gtaccctact
    12781 cactagtctc atatattttt cggaggtttg caacatcctc ttcctggata ccataaaagg
    12841 aacctgctgg ttgcatgaca gacttctcat ctgtatggtc caagccaatc gcatgaccta
    12901 actcatgttc tgccgtatgg acaaggcgtt cataggagta gccatagtat ggattggaca
    12961 aataataatg attcaaccgc accgttacgg acaagaattg ccctgttaag agattagttt
    13021 gactttccgc ctctcctgcc acaggagtgc ctccgtcgtt catctccgta gccgtaatat
    13081 ccgccttact agactcagtc acgagttcaa agttaaaagc accagtttga ttccagttct
    13141 ggattgcttc taaataagcc tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac
    13201 gagcagaggc ctgtgcccac cttccttcag aatgctggtg actatctgtc tggcttaact
    13261 taggcagttg ccctgttttc tcccattggt caatactttg ttgacccatt tttactgacc
    13321 gttctgcttg ctttagcgct ccttgaaaat ccccgttcag ataccagaga agtccgaaag
    13381 caagcacaca taagagcaca actatccaaa ccagacgcca aaacaaacgc cacacaaaag
    13441 aaaagaaagc ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat
    13501 aagaattatt ttactaaaag aagctaaaag aaatctaaat actgactttt tcatcttaac
    13561 gtcctactat ttttttgagt aactggatag ctttgtattt taaaggcgat ggatggtaac
    13621 ggaaagtacc tgctttgcgt acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac
    13681 catcacttcc atcaaaaatc ccttgaatgc ctaggaagtt gtatttaggt attccacgtt
    13741 ttatgctttc caacataaca tatttttgaa gcagtgcagg ggcatagaac ttattaaact
    13801 cagtgtagga accactaaag agataagtcg tttcctgagg catataaaca aataaactcc
    13861 cagctaaaac aatatcttct tctccatatt tttcaatcaa gtctcgcgct tctgcttttc
    13921 gaacttcaaa cgtttcaaat tgactagaat attctctcag ttgattttgt tttttctcag
    13981 aatgaggatt tttactcaaa tcaagtcgca acttgtccaa gttttcttct agtttacttt
    14041 gttcaccttg caatttgctc atatactccg aaaaattcaa gcttgctatg agaaactccg
    14101 cttgttctcc aaaagtatca taaaaatgct cataatattc taaactttta tcactatatt
    14161 ctctacgttc agaggtttct tttgttatat tcttaaaaat cgatagttct tcacgtttta
    14221 actttttcaa ccgaatgcca aaggtttcag cctttttcac caagggttta ccctttttgc
    14281 taaaactttt aagcaaactc ttttcagtta attcagttaa atctttatag tataaccaat
    14341 ctggttctcc acctgggtaa cctgttgtta agccatcaaa ttgataacct aaatcagtca
    14401 aaccttgaat aatacttttt ttctcagcat ctattggatt accttggcta tcaaaagttt
    14461 gataagtttc ataaggtttt acaagcaact ctaatacacc attttgcttg gcatattctt
    14521 ttaactctgc ataaaaaact ggaagagcat cttgttgggt ataaatcggc cccgaattga
    14581 gttccatatg cagaccaccc agcatgggca agctataaac cagagctgca acttgaattt
    14641 ctccttcttg tttcaaagca agataaacaa ttcgagcccc tcttttttct agcaaatccc
    14701 ccatctggac agattgcata aaggaacgag aagaaacctg atcagaataa gtctgaaact
    14761 cttctttcgt gagtgttgtt agtgccatat acttactttc tatgtttttt tcttaatgtt
    14821 ttacggaaat caagagcaag tcttaacaga ggatagagag gatgagtggg cattgtaaat
    14881 tcacccaagt attcttcaat cgttggatta aatttttcct taaaatgata aagtccacca
    14941 ttgagagagt tttcaacacc acctaaattt tgccagacca tacctcgctc aaaggcatag
    15001 cgagccgttt cataccatgt taaaattggt gcattgtaac gtttaaaatc atcatccata
    15061 ccagcatata tattgacaga ggtagtacca aattccaaac tcaaagtagc cgctaaagga
    15121 actctcgctt gacctacatc tatatattcc tgcaagaagg tcaattcctc taacaaacgt
    15181 tctttttcct tcttctgcgc ttctactttt gaagttcgag tcgactcagt aaaggtctct
    15241 tccaaggctc tatttttcgc taactgttct tctaactctt gcgaacgttt agaaacatcc
    15301 aaggtggcca aggtgatata ggccttgtcc ttaaaattat ctaacaattt tttataatag
    15361 gcttcattcc tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat
    15421 gaatctaata gttccagtcc accatattga atctcaagcc ctttgtttcg tgctgttcga
    15481 atagcctgtt ttgttgactt ggaaagttta tcttcttcaa aattttcctt gtatattttc
    15541 gcctgaatac gaggttgaat ggtgtctccc atttcctccg tttttcctga ccaccttact
    15601 cccatttgtt gcaaactatc aataatagcc agattttcag gaaattctgt cttttcctga
    15661 ttgattaaac tttgagatag gcaaatactt gggtcaaaag tcacaaaaac cgctctctta
    15721 ctgcgagcat aggacttaat agactgaatg gcaaaattca agagttcttt atccccataa
    15781 tccaatatag gtcctcttgg gatgtaaaac attttatagc ctagcggaag agttctaatc
    15841 aaaatactag ctgtcgccag taatttttct tccctgtaaa caccaaactt ctcatgttgc
    15901 caattagact taacttcctc ccaagcacta ctttgtaata cattggctaa ttcatgttct
    15961 ttgacaaact gatcatattc taatgtggga atgccaattt gataacggta catttcctac
    16021 tctctttcct ccagtatttt attactattc tactactttc gtttgaaaag tctagtgaaa
    16081 acatatttta ttttagttct actcccccta tgctgaagtt caaactaagt cagtctctct
    16141 tctaatttga aatcaattgg tagggttgtt aaaaaaactt ccaattgttt ttcccagtag
    16201 taccactcgt gagttccagc gctatggcta taggtcacat caaaacctag ttttttgaga
    16261 tttttcactg cgagattatt ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa
    16321 agtttggtct ttttatccga ttttttagcc agactttcaa gagaataggg actagttgtc
    16381 cagtctctaa tctctccaaa aacacctctc cagtaggctg gacttcccag attttgactt
    16441 tcaggagaaa agttttgaaa gctgagggca cctgaaaaac tagctgcatg agaaaaacga
    16501 tttgtcgcaa gagccagttt gaagcagccg taacctccca tagaaagacc agcgataaag
    16561 gtcttttcac gcttgctagt catattaggg aagaagcgtt tcagaacctg tggcaattcc
    16621 tctgctagag ccgtgtagta gtcaaaacca tactgggtat cggtgtacca accattgctg
    16681 gtattgggca taacaacgat gagattagtt cctcgaagca agcgttctac attggtccgc
    16741 ttaagccaac tattatgatt tccagacatc ccgtgcaaaa ggtacaagac gggaatatct
    16801 tcacactctg gttcttccac tcgattggca tcagggtaga ggacattcac cccccactcc
    16861 atatccaata cttgtgagta atactcgatt ttcattactg ccatgatttt ctccttctat
    16921 ttttctataa gaaaaagccg aaactcgact ttctctctgt ttatttcaac gattattttg
    16981 cttccatgac tactggtaaa atagctggac gacgcttggt ttggtcaaag agatacttgg
    17041 tcaaattatc tcgaaccttc cctttaagat ctgcccagtc aaagtcatct ccttgaagat
    17101 aatcttctac cgtttggtta atcaattctg aactttcacg gagaatatcg cgactcttct
    17161 tgagataaac aaatccgcgc gtatgaacac gagccctagc cacaattttc ttctcacgac
    17221 ggttgactgt aatagccacg atgaaaattc catcctctga caagatctta cggtcacgaa
    17281 gaacaacatt tccaacatca ccaatggcat tcccatcaat caagatatct cctgctgaaa
    17341 ccgatccagc tggaacaaag tctccattct cgtaagccat ggtcgtcccc tttttaggaa
    17401 tgaagatgtg ttctggcaac atcccaactg ccatggcagc cttagcgtga gcatccaact
    17461 cacgatactc cccttggaca gggaagaggt acttaggttg caaaagattg atcatcagct
    17521 gcaaatcacg cacatttccg tgccctgata catgtaaact ttgggtaatc aatttgacaa
    17581 ccccacctgc ctgataaatc atattttcca cacgcgcaac aaaggcttct ttagcaatag
    17641 acggagccgt agcaatatag accaggtccc catccttgat ttctacataa cgatggcgac
    17701 caatcgacat cttacgaagt ccattgatag gttcacccat acgacctgtc tcaagaataa
    17761 tcaactcatg gtcttcaaag cgagacatat ctttaggctt aatcaagaga atttcgttgg
    17821 ctaaagacaa cttcttaaga cgaatcgctg tgcggacgat attttcaata tcaaatcctg
    17881 tcaagacgat acgtcgacct gttttatccg cagcgtcaaa aatctgctga atacgagaaa
    17941 gattactgga aacagctgca acgatgatac gaccttccca gtcagcaata gtttgggtaa
    18001 tttcatccct aacttcactt tcactagcca cctgaatatt gctgtctgca ttggccgaat
    18061 cactgaggag agccaggacg ccgtcacgac caatctctgc caaacgagca aaatcagttg
    18121 cataagattc actagccgtt tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt
    18181 ccgatgtctt caagacaatt cccagactct ctggaacgga gtaagtcgta gggaagaagg
    18241 aaaccactgt cccaccaaaa tcaatctccg tattctcatc aatgacatgg aaatcattaa
    18301 atttcttaac ggcatcattt cctttgacaa agagctttgc caactcaatg gtcaactcag
    18361 acccaaatac aggaacttta gcctctgcca agagataagg tagagcacca atggcatccg
    18421 catgcccgtg ggtcaagaaa accccagcaa tacggtcgct attttcaaaa aggtaatcca
    18481 tgtttggaat caccacatcg acccctaatt gttcattttc aggatatttt aaccctacat
    18541 tcaaaacaaa aatggactct ccaatttcag caatgtacat attttttcca ttctcacgca
    18601 caccaccaag tgttgttaaa ctgatattac tcatttttcc tccaaaatct tagtttatct
    18661 tgattatagg gcaattctac cctcttattc taaaagttct gatactttca gccgaatctt
    18721 ttcctaccat tataccattt ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag
    18781 agttgatttc ccaactcttt cctaacttct actctttttc catcaaaaaa tcataaattt
    18841 cttgcaccgt acccagcgcc atcatttctt ggtctttaac ggtttgtttg agattttggt
    18901 aaatttgact ttctcctatc tcccgctttg gcgcctcttt attgactgtc atcacaccat
    18961 cttttatcgt cacaaagcct agttcttcaa atacttgaat catcttgacc agcaagattt
    19021 gttgaatatt aagatatgca gccaaatctt tcagcttgta gcgaatatca aactctggga
    19081 actggtaaat agtcttgtac aatttagcaa actgatctct agtcccataa cctgtcagat
    19141 aataggtctt gtcaatatca tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa
    19201 tggtcttcag ctgagtaata tcctctggaa tgttttttac gacaacagct tcactagccg
    19261 caagatttgg cagttctcca ggaaaatcca agactggaac accttctggc aagactgcat
    19321 tttttccacg aatgttaaaa agttgaacac cttccactcg cgcatccacc atcatcaact
    19381 ggagggcagt ttggccattc cattggttga cagacaattt aaccgctaac tctagattct
    19441 tggtttgaga aaactctgtc gcccatctgc cttgaccaaa ggctaccact tcaaaactcg
    19501 cctcaccctt ggaaattttc agctttagat gggcattacc tgcccccata gtacgagcac
    19561 tttcgacctg aaaattcttg atataaaaaa taggtttctg attatccatt ccaaaaggag
    19621 ctaaacgttc aaaacttttg accgtttcca agctaagtgc ctccaaatcc aactcttcat
    19681 ctaggtttaa cttattcttg ccaccagcat ctgcaccttt ttcacgaaca taatcttcca
    19741 aaacctgaga taaatctgag agttgctcaa cttccagcgt catacccgct gcacctgcat
    19801 gacctccaaa ggcgatgaag aggtctcgat ggggatccag agcttcaaaa atatcgaccg
    19861 cttccacact acgagcactg cccttggcac gaccgtcttc tatattaaga acaatgactg
    19921 tctgtcccaa ttcttccaat aaacgaccag ccacgattcc tagaacccca ggattccagc
    19981 cttccttggc caagacctga accttcttct caggatccac catggtcttg gcttcttcat
    20041 agatagactg aacgatttcc ttgcgctctt cgtttttctg gtgaatcata agggcaatct
    20101 catgcgcttc ctcatcatca aatccagtca acaaatcaat ggcaggattg ggatcatcca
    20161 agcggcccaa ggcattcaaa cgaggagcaa tctggaaacc aaccgtttct tctgttactt
    20221 cgttggcagc aatcccagcc atgtccagca tttcttgcag accaatgcgc tgggtatgac
    20281 ccaacatttc cagaccatat tgaactaaga tacgattttc atccgtcaga ctcaccatat
    20341 ctgcaatagt tccaatagcg accaaatcaa gcaattccac ttgcacttct tctaacaggg
    20401 cacaagccaa cttgaaagca actccacaac cagccaaata tttaaaagga taatccgcat
    20461 ctggatgttc aggatggaca atagcataag catctggcag ggtttcaggc atggaatgat
    20521 ggtctgtcac aatgacatct actcccatag actgagccaa tgcaatagcc tcatgaccag
    20581 caaccccatt gtccaccgtc acaatcaagg aaattccttc ttgctcgata aagtatttat
    20641 aaacactagc attagggcca tagccatcgg taaaacgatt tggcaggtaa actcggcact
    20701 cagcaccaag ttgttccaaa ctttccttca caatagaagc cgaagtcatg ccatccgcat
    20761 catagtctcc ataaacgaga atattttccc cttcttcaat agcctgacga atccgctcca
    20821 ctgccttgtc catatcatgg agcagataag catcatgtaa gtcctccaag gaaggttcta
    20881 aaaacttctt cagactttct tggtcctgaa tccctctctc aaacaataac cgagccacct
    20941 caggacccag tccagccttc ttggctatct ttgtaaaatc cgcatcttct acctgcaggg
    21001 caaactgcca ttcataagta ggtgttatca aaaagacatc cactctttct aagaattcta
    21061 ttgcttcatt ataacatgat ttagacgttt tctctatcca gattgctttt ttataacatt
    21121 ttatagtata ttgaaactag aatagtacac ctctacttct aaaatattgt tagaaatcga
    21181 tttgactgtc ccgatcgatt tgtcctgttc ttatttcact atagtgaatt ttttcagata
    21241 tggtttgaca agaacattct ttcattgtag aatcgtgtta taaaatataa cacaaaggag
    21301 atctctcatg gctttagtag aatttaaaaa cgtcgaaaaa tattacggag actaccacgc
    21361 actccgcaac atcaatctcc gttttgaaaa aggacaagtt gttgtcctgc ttggaccttc
    21421 tggctctggg aagtccactc ttatccgtac gatcaatggt ttagaggctg ttgacaaagg
    21481 aagtctccta gtcaatgggc accaagttgc tggtgccagc cagaaagatt tggtacctct
    21541 tcgcaaggaa gtcggcatgg tttttcaaca ttttaacctt tatccacaca aaacggtgtt
    21601 agaaaacgtg acacttgcgc ccattaaagt tctaggaatt gataaaaaag aagctgaaaa
    21661 aaccgcccaa aaatatctgg aatttgtaaa tatgtgagac aagaaagatt cctatcccgc
    21721 catgctatct ggtggacaaa aacagcggat cgccatcgct cgtggtcttg ctatgcatcc
    21781 ggaactcctc ctctttgatg aaccaacatc tgctcttgat cctgagacta tcggagatgt
    21841 tctagcagtt atgcagaaac tggcgcatga tgggatgaac atgatcatcg ttacccacga
    21901 aatgggcttt gctcgagagg ttgcggaccg cattatcttt atggccgacg gagaagtttt
    21961 agtagatacg acagatgtcg ataacttttt tgacaatcca agcgaacctc gtgcccaaca
    22021 attcctcagc aaaattatca accacgaaag tgacaaagtc aaataaggag gcgcctatga
    22081 aaaaaaattc tttttatcag cattattgat tagccttttc ggccttgctg ctgccaaacc
    22141 agtccaggct gatactagta tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt
    22201 caaacaagac gttcccaatt ttggttacaa agatcccaag accggtactt attctggtat
    22261 cgaaaccgac ttggccaaga tggtagctga tgaactcaag gtcaagattc gctatgtgcc
    22321 ggttacagca caaacccgcg gcccccttct agacaatgaa caggtcgata tggatatcgc
    22381 gacctttacc atcacggacg aacgcaaaaa actctacaac tttaccagtc cctactacac
    22441 agacgcttct ggatttttgg tcaataaatc tgccaaaatc aaaaagattg aggacctaaa
    22501 cggcaaaacc atcggagtcg cccaaggttc tatcacccaa cgcctaatta ctgaactggg
    22561 taaaaagaaa ggtctgaagt ttaaattcgt cgaacttggt tcctacccag aattgattac
    22621 ttcccttcac gctcatcgta tcgatgcctt ttccgttgac cgctctattc tgtctggcta
    22681 cactagtaaa cgcacagaac tactagatga tagtttcaag ccatctgact acggtattgt
    22741 taccaagaaa tcaaatacag agctcaacga ctatcttgat aacttggtta ctaaatggag
    22801 caaggatggt agtttgcaga aactttatga ccgttacaag ctcaaaccat ctagccatac
    22861 tgcagattaa ggaggacacc ccatgataga tttatcatct tggacagcct attttcagga
    22921 ttttggacaa tttttcaatg gtttcctctt tactcttgcc ctagcgattg gatcctttat
    22981 cctcgccatg gtcttaggaa tcttctttgg tgccatgtca accagtaaac gtccaatttt
    23041 acgcatttta gctcacatct ttgtggaatt ttaccaaaac actcccctct tggtgcagtt
    23101 tgttattgtt ttttatggcc tacctcttat cagtgaccat actatcatga ttccaattta
    23161 ttggacagct gttctctgca tgggactcta tcacggcgct tatatcgctg aggttattcg
    23221 ttcagggatt cagtctattc ctagtggtca gatggaggcc gccttgtcgc aaggttttac
    23281 ctatatcagt gccatgcgct tgattatctt gcctcagacc ttccgcatca ttctccctcc
    23341 attgaccaac caaattgtta acctcatcaa gaacacctct actgtagcta tcatctctgg
    23401 agtagacttg atgtttgtga ctaagtcttg gtcggctctc aacggaaact atatcccagc
    23461 ctttttaggt gctgctcttc tctactttgc tctatgcttc cctgttgccc agtttggtcg
    23521 caagatggag caagccaaca aaaaagccta ttcactttag gaggttacta tggaatctat
    23581 tttagaagtt ttaaccccag ataacctagt ctttatcttt aaaggatttg gcttgaccct
    23641 ctatatttct ctgattgcca tcatcctctc tactatcatc ggtacggtgc tagctgtcat
    23701 gagaaatggc aaaaatcctg tcttacgcat tatttccagt atttatatcg agtttgtgcg
    23761 caacgttccc aaccttctct ggatttttac tatctttttg gtgttcaaaa tgaaatccac
    23821 accagcaggt attacagcct ttactctctt tacatcagca gccttggctg agattattcg
    23881 aggcggtctc aataccgtag acaagggaca gtacgaagca ggaatgtcac aaggcttcac
    23941 ctcagcccaa atcctctact acatcattct cccacaagcc atccgcaaaa tgctaccagc
    24001 catcatttct cagtttgtta ccgtgattaa ggataccagt ctcctctact ctgttatcgc
    24061 cctacaagaa ctctttggag ccagccaaat tctcatgggc cgttatttcg aaccagagca
    24121 ggtcttcagt ctttgcatcc tgattgccct catctacttc agctttaacc tagcaatttc
    24181 tagcctgtct catatgctag ccaaacgttg gcaacaagct gcagaataat actcttcgaa
    24241 aatctcttca aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt
    24301 ctatccacaa cctcaaaacg gtgttttgag cagcctgcgg ctagcttcct agtttgctct
    24361 ttgattttca ttaagtataa acagccactc tccagttcaa ttggagagtt ttttgatgag
    24421 agtagatatt tatagacctc aatttgacac catacatttt ctatgataaa atgtaacaaa
    24481 ttcatttaca acaaatcgaa atctaaatga aatggaattt tctatgaaat cagtcaaagg
    24541 actactcttt atcatagcta gttttatctt gactcttttg acttggatga acacttctcc
    24601 ccaattcatg attccaggac tagctttaac aagcctatct ctgactttta tcctagccac
    24661 tcgtctccca ctactagaaa gctggtttca cggtttggag aaggtctaca ccgtccacaa
    24721 attcacagcc tttctctcca tcatcctact aatctttcat aactttagta tgggcggttt
    24781 gtggggctct cgcttagctg ctcagtttgg taatcttgcc atctatatct ttgccagcat
    24841 catccttgtc gcctatttag gcaaatacat ccaatacgaa gcttggcgat ggattcaccg
    24901 cctggtttac ctagcctata ttttaggact ctttcacatc tacatgataa tgggcaatcg
    24961 tctccttaca tttaatcttc taagttttct tgttggtagc tatgcccttt taggcttact
    25021 agctggtttt tatatcattt ttctatatca aaagatttcc ttcccctatc taggaaaaat
    25081 tacccatctc aaacgcttaa atcacgatac tagagaaatt caaatccatc ttagcagacc
    25141 tttcaactat caatcaggac aatttgcctt tctaaagatt ttccaagaag gctttgaaag
    25201 tgctccgcat cccttttcta tctcaggagg tcatggtcaa actctttact ttactgttaa
    25261 aaattcaggc gaccatacca ataatatcta tgataatctt caagccggca gcaaagtaac
    25321 cctagacaga gcttacggac acatgatcat agaagaagga cgagaaaatc aggtttggat
    25381 tgctggaggt attgggatca cccccttcat ctcttacatc cgtgaacatc ctattttaga
    25441 taaacaggtt cacttctact atagcttccg tggagatgaa aatgcagtct acctagattt
    25501 actccgtaac tatgctcaga aaaatcctaa ttttgaactc catctaatcg acagtacgaa
    25561 agacggctat cttaattttg aacaaaaaga agtgcccgaa catgcaaccg tctatatgtg
    25621 tggtcctatt tctatgatga aggcacttgc caaacagatt aagaaacaaa atccaaaaac
    25681 agagcttatt tacgaaggat tcaagttcaa ataagtaatc atactctcct gggatttccc
    25741 aggagagttt tttatagcca aatgaaataa aaccggaacg atggaatttt ggcattcaaa
    25801 tcaattgata agaatatttt atagtggagt gaaataggat acgaacaaat tgattaggaa
    25861 aatcaaatga atttatagaa atcttttagc agttatgttg tcctattcta gtttcaaaac
    25921 gctatagaag cagcattgtg ctagtctaga ttcagtttac tatactaaaa cgagtagctt
    25981 gaaatcaaaa aacccaccct cacaggcagg ttttatctgt attattcagc tagattatgc
    26041 tttaccttct gaaccgaata cgtcgatacg ttcttcaacc gatgcttgga tagcttttac
    26101 accgtcagcc aagaatttac gtgggtcgaa gagttttttc ttgtcgtatt ctgcttcgtt
    26161 tgcttcgtag tcacgagcaa atttacgagt tgcgttagcg aatgcgattt ggcattctgt
    26221 gttaacgtta actttggcaa caccaagttt gatagctgct tggatttgct catcaggaat
    26281 acctgatcca ccgtgcaata cgattgggaa tcctggaaga gcttctgtca atttttgcaa
    26341 gtggtcaagg tcaagacctt cccagtttac tgggtaaggg ccgtggatgt taccgatacc
    26401 agctgccaag aagtcgatac cagtttcaac cattgcttta gcgtcttcga ttggagccaa
    26461 ttcaccttta ccgatgattc cgtcttcttc accaccgata gtaccaactt cagcttctac
    26521 tgagatacct ttagcgtgtg ctttttcaac aacttcttta gccaatttaa ggttttcttc
    26581 aactggaagg tgtgaaccgt caaacatgat tgaagtataa ccaacttcga tacactcaag
    26641 tgcatcttcg tagtgaccgt ggtcaaggtg gatagctact ggtacagtga tacccattga
    26701 ttcaacaagg ttagcgatca agttgcgagc aactttgtaa ccacccatgt atttagcagc
    26761 acccattgaa gtttggatca aaactggagc ttttttagct tctgctgcgc gcaagatagc
    26821 ttgagtccac tcaaggttgt ttgtgttaaa tccaccaact gcataaccgt tgtcacgggc
    26881 tgcttggaca aatttttctg ctgaaacgat tgccatttta tcaggcctcc tgtatatttt
    26941 tatgggtcat cccatttaca ttgttcattt tatcactttt tgccaaaaaa atctagtttt
    27001 tcccgcagtt tcgattgatt ttcttctaac tccatctatg taaacccttt ctctccctag
    27061 tcttggacga cttttggaaa atctataaag aaggttaaac gattctcctc catctcgaaa
    27121 cgataagcta atttttcatg ttctaataga ctcttaacca caaagagccc cataccagac
    27181 cccttgacct tgcgactggc attgtcagaa aaagactggg ctagtttttc ttgttcctct
    27241 gagctacagc tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca
    27301 cctggaacag agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact
    27361 gatgggttta gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc
    27421 ttggctagca aggcataatc tttgaccaga ttttgcgtca tctggaggag gtcaattgtt
    27481 tccctatcat ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga
    27541 ttgagttcat ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga
    27601 ccgatattct ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat
    27661 tcatgagaag ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca
    27721 ttcttttcat gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt
    27781 tccttgagat tacctatctc atccttagaa tccacgcgca atcgcacttg ggaatccagg
    27841 tccatcatcc gacgggtcac ccgcttgatt tccaagatcg gtgcaacaat agtccgagcg
    27901 tagatgtagg ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac
    27961 tggagactga tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc
    28021 atagtagcac cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg
    28081 cggtctgtgt ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct
    28141 ttgacggtcc ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc
    28201 tgcctatctt tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc
    28261 tgacgatgac tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata
    28321 accagaacac taaatatcga gaaggtatag ataaatatct ttgcaaataa acctgttcgt
    28381 ttcattttcg ctccaattta taaccaacat tgcgcacagt gaggatacaa tccaagtcta
    28441 gctttttccg caattccttg atataaacat caataacacg gtcaaaggga acctcatctg
    28501 tcgctttcca gacggcatcg ataatctgag atcgagtcaa ggcccggcct tcatttttca
    28561 ctagatagtc cagaatttcc aactctttgg cattgatagg cacttcttga cctgcgatgc
    28621 ttgcactgta gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat
    28681 cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa aagggagagg gagaaaggtt
    28741 tttccagata gccatctgcc aaagaggcaa aggcactcat cttgtattcc tcatcttgaa
    28801 aagctgtcaa catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta
    28861 agccgttgag cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa
    28921 attgctccag agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca
    28981 aataatcact gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac
    29041 tttaactgct ctctattttt tatttttctt agaataaata cctactctat tttctattat
    29101 agtctcttgc tggccttttg tctgcaagca actgaccact agataaaacg ttgtgaaatt
    29161 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    29221 gcaactgaaa gcaatgattt tcaccactgc tttcggattt attttgaatt gttaaatagc
    29281 cattcctatc cactattctt gaatagaaac acaagatgca atctttattc tagactcatt
    29341 ttttcaaatt tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct
    29401 tgaagcaagc gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa
    29461 gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc
    29521 tgcaccacca ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga
    29581 agtcacattg gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta
    29641 agcagaaact agagcaggga tagcaatcaa gatagattcg gtgatgaatt gacccaagat
    29701 acttgcctgc ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat
    29761 ccaaaggctg agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag
    29821 gaggttggcc atcttgtaca taccagagat agattgctca agagctgggt agttagagga
    29881 gctcttgacg agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat
    29941 aacatcatcc aagttcttgt ctgctgttac aaagaaggtt gcgtccccat aaatggctgt
    30001 gtcttctgtg tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc
    30061 gtaaagttct tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat
    30121 tgtcacttca actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc
    30181 cagtttaacc ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag
    30241 gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga
    30301 gacaaacttg tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa
    30361 acgcttggca cgatcagcag tgagattctt cttggtttct ggcgtttcaa tcaggtcata
    30421 tccagtcaaa tctccgatag cgttgatacg tttgacataa gactcgatgg ccttgttttc
    30481 ggtgattttt ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt
    30541 gacgcgacga ttgatttgca tggagaagct attagtgata tttttaaagg tctcctgaga
    30601 agccttggca gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag
    30661 aataatcagg aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt
    30721 gtgtaacata gattcccttt ctagattttg ttttaatcat tctatcaaaa taagctcaaa
    30781 ttatttacta gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc
    30841 tgacgcttgt gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg
    30901 ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt
    30961 tggctcatca gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg
    31021 ttgctgttga ccacctgata actggagaac attccgcttg atctggcttt catccaaacc
    31081 aagctcaaga agtgtatcct tgcttgcctt tttgttgacc aagcggatat tttccagcgg
    31141 agaaagataa tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg
    31201 gtaagaatag cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg
    31261 actatctaga ccagcaagta gggacaagag tgtggatttt cctgctcctg actccccaat
    31321 aatactgtaa aattttccag gttcaaaatt ataatcgatc tgatatagga ctgcttcagc
    31381 agtattctta taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc
    31441 ttaactaata gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag
    31501 ggctacagat aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat
    31561 gctagttgat aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact
    31621 tgctagtaga gtttggagta gataacttgt gattccgttt cctgcaacaa atgctggaag
    31681 caaagctcca agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt
    31741 gccttttcca agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga
    31801 caaaaccaga attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcaa
    31861 gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc
    31921 gacttggtag ccttgatttt ccaaggccaa gttttctacc tgcttcatga gtccgtccat
    31981 ttccttagga ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa
    32041 aagggtttgg ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa
    32101 gcctgtgaat ttctcttgtt ttttaccaga aaagatgccg ataatctcaa actctactgt
    32161 ttgtcctttt ccagattcag actgaccagc atccaagcca atcttgtcat gaagtgaaag
    32221 accgttcttc ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag
    32281 gtgtcgccct tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc
    32341 ctcaagagcc gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac
    32401 gctctgctca ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg
    32461 agagacattt tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt
    32521 ctgaccattc tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct
    32581 ttctactgtt ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac
    32641 caataaaatc agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga
    32701 tctttggatt ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata
    32761 tgaaatgttt atgaaatacg aaaaaaaata tcgagtaggg gataatctct agcccctctc
    32821 acaccaccgt acgtgccgtt cggcatacgg cggttcaact aacttttaac gcatgtcgtt
    32881 caaggtaata atccaaacac gaaacctgtt cacgtttttc aaggactggt tttgatatag
    32941 cacgtttaag taccgacttc tgagctacta tagtagattg aaactagaat agtacatctc
    33001 ttcttctaaa acattgttag aaatcgattt ggctgccctg atca
//
LOCUS       DAVBED010000020        31002 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBED010000020 DAVBED010000000
VERSION     DAVBED010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.020"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQ547_000927"
     CDS             complement(298..516)
                     /locus_tag="VQ547_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542794.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQ547_000928"
     CDS             complement(762..1040)
                     /locus_tag="VQ547_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542795.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ547_000929"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ547_000929"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2542796.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQ547_000930"
     CDS             complement(2959..3933)
                     /locus_tag="VQ547_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2542797.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ547_000931"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ547_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2542798.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQ547_000932"
     CDS             complement(4621..5595)
                     /locus_tag="VQ547_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2542799.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQ547_000933"
     CDS             complement(5603..6859)
                     /locus_tag="VQ547_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2542800.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQ547_000934"
     CDS             complement(6921..7352)
                     /locus_tag="VQ547_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542801.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQ547_000935"
     CDS             complement(7354..7956)
                     /locus_tag="VQ547_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2542802.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ547_000936"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ547_000936"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2542803.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ547_000937"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ547_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2542804.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQ547_000938"
     CDS             complement(9855..10445)
                     /locus_tag="VQ547_000938"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2542805.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQ547_000939"
     CDS             10568..10750
                     /locus_tag="VQ547_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2542806.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ547_000940"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ547_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2542807.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ547_000941"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ547_000941"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2542808.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQ547_000942"
     CDS             complement(13298..14374)
                     /locus_tag="VQ547_000942"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2542809.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQ547_000943"
     tRNA            complement(14716..14788)
                     /locus_tag="VQ547_000943"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQ547_000944"
     CDS             complement(14888..15397)
                     /locus_tag="VQ547_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2542810.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQ547_000945"
     CDS             15520..15951
                     /locus_tag="VQ547_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2542811.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQ547_000946"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQ547_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2542812.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ547_000947"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ547_000947"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2542813.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ547_000948"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ547_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ547_000949"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ547_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2542814.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ547_000950"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ547_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2542815.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ547_000951"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ547_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2542816.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQ547_000952"
     CDS             complement(21342..23105)
                     /locus_tag="VQ547_000952"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542817.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQ547_000953"
     CDS             complement(23427..23930)
                     /locus_tag="VQ547_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2542818.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQ547_000954"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQ547_000954"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2542819.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQ547_000955"
     CDS             complement(25548..26177)
                     /locus_tag="VQ547_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542820.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQ547_000956"
     CDS             26142..26363
                     /locus_tag="VQ547_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542821.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQ547_000957"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQ547_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQ547_000958"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQ547_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ547_000959"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ547_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2542822.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBED010000021        30854 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBED010000021 DAVBED010000000
VERSION     DAVBED010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.021"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            68..322
                     /locus_tag="VQ547_000960"
     CDS             68..322
                     /locus_tag="VQ547_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2542823.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            666..2000
                     /gene="trmFO"
                     /locus_tag="VQ547_000961"
     CDS             666..2000
                     /gene="trmFO"
                     /locus_tag="VQ547_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2542824.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2084..2821
                     /locus_tag="VQ547_000962"
     CDS             2084..2821
                     /locus_tag="VQ547_000962"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2542825.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2830..3387
                     /gene="frr"
                     /locus_tag="VQ547_000963"
     CDS             2830..3387
                     /gene="frr"
                     /locus_tag="VQ547_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2542826.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3447..4301
                     /gene="cvfB"
                     /locus_tag="VQ547_000964"
     CDS             3447..4301
                     /gene="cvfB"
                     /locus_tag="VQ547_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2542827.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4310..4525
                     /locus_tag="VQ547_000965"
     CDS             4310..4525
                     /locus_tag="VQ547_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2542828.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4611..5579
                     /locus_tag="VQ547_000966"
     CDS             4611..5579
                     /locus_tag="VQ547_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2542829.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5759..6259
                     /locus_tag="VQ547_000967"
     CDS             5759..6259
                     /locus_tag="VQ547_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542830.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6262..6522
                     /locus_tag="VQ547_000968"
                     /pseudo
     CDS             6262..6522
                     /locus_tag="VQ547_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6889..8000)
                     /gene="ald"
                     /locus_tag="VQ547_000969"
                     /pseudo
     CDS             complement(6889..8000)
                     /gene="ald"
                     /locus_tag="VQ547_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8177..8746
                     /locus_tag="VQ547_000970"
     CDS             8177..8746
                     /locus_tag="VQ547_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542831.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8814..9464
                     /locus_tag="VQ547_000971"
     CDS             8814..9464
                     /locus_tag="VQ547_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2542832.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9448..11688
                     /locus_tag="VQ547_000972"
     CDS             9448..11688
                     /locus_tag="VQ547_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2542833.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11868..12056
                     /locus_tag="VQ547_000973"
     CDS             11868..12056
                     /locus_tag="VQ547_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542834.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12088..12675
                     /locus_tag="VQ547_000974"
     CDS             12088..12675
                     /locus_tag="VQ547_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542835.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12679..13854
                     /locus_tag="VQ547_000975"
     CDS             12679..13854
                     /locus_tag="VQ547_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542836.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14028..14159
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14175..14705
                     /gene="infC"
                     /locus_tag="VQ547_000976"
     CDS             14175..14705
                     /gene="infC"
                     /locus_tag="VQ547_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2542837.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14738..14938
                     /gene="rpmI"
                     /locus_tag="VQ547_000977"
     CDS             14738..14938
                     /gene="rpmI"
                     /locus_tag="VQ547_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2542838.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14990..15349
                     /gene="rplT"
                     /locus_tag="VQ547_000978"
     CDS             14990..15349
                     /gene="rplT"
                     /locus_tag="VQ547_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2542839.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15407..15787
                     /locus_tag="VQ547_000979"
     CDS             15407..15787
                     /locus_tag="VQ547_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2542840.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16037..16837
                     /locus_tag="VQ547_000980"
     CDS             16037..16837
                     /locus_tag="VQ547_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2542841.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16800..17786
                     /locus_tag="VQ547_000981"
     CDS             16800..17786
                     /locus_tag="VQ547_000981"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2542842.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17828..19729
                     /locus_tag="VQ547_000982"
     CDS             17828..19729
                     /locus_tag="VQ547_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2542843.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19790..21445)
                     /gene="pavA"
                     /locus_tag="VQ547_000983"
     CDS             complement(19790..21445)
                     /gene="pavA"
                     /locus_tag="VQ547_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2542844.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21550..22047
                     /gene="ybeY"
                     /locus_tag="VQ547_000984"
     CDS             21550..22047
                     /gene="ybeY"
                     /locus_tag="VQ547_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2542845.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22028..22423
                     /locus_tag="VQ547_000985"
     CDS             22028..22423
                     /locus_tag="VQ547_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2542846.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22440..23339
                     /gene="era"
                     /locus_tag="VQ547_000986"
     CDS             22440..23339
                     /gene="era"
                     /locus_tag="VQ547_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2542847.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23388..24212
                     /gene="mutM"
                     /locus_tag="VQ547_000987"
     CDS             23388..24212
                     /gene="mutM"
                     /locus_tag="VQ547_000987"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2542848.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24212..24817
                     /locus_tag="VQ547_000988"
     CDS             24212..24817
                     /locus_tag="VQ547_000988"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2542849.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24804..26003
                     /locus_tag="VQ547_000989"
     CDS             24804..26003
                     /locus_tag="VQ547_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2542850.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26003..26152
                     /gene="rpmG"
                     /locus_tag="VQ547_000990"
     CDS             26003..26152
                     /gene="rpmG"
                     /locus_tag="VQ547_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2542851.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26192..26425
                     /gene="secG"
                     /locus_tag="VQ547_000991"
     CDS             26192..26425
                     /gene="secG"
                     /locus_tag="VQ547_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2542852.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26527..28881
                     /gene="rnr"
                     /locus_tag="VQ547_000992"
     CDS             26527..28881
                     /gene="rnr"
                     /locus_tag="VQ547_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2542853.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28844..29311
                     /gene="smpB"
                     /locus_tag="VQ547_000993"
     CDS             28844..29311
                     /gene="smpB"
                     /locus_tag="VQ547_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2542854.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29327..30187
                     /gene="tehB"
                     /locus_tag="VQ547_000994"
     CDS             29327..30187
                     /gene="tehB"
                     /locus_tag="VQ547_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2542855.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30260..>30854
                     /gene="coiA"
                     /locus_tag="VQ547_000995"
     CDS             30260..>30854
                     /gene="coiA"
                     /locus_tag="VQ547_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2542856.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9165 a         5712 c         7071 g         8906 t
ORIGIN      
        1 aagtcgtgcg ctgaacacca acaagacgct taaatcgtgc atcagttagt tgtttacttg
       61 cttcataatt catagaacta ctataccata ttttgtttcg caggaagtct attggaaagt
      121 aagaaatatt ggagctgagg cgattagaag aaattgtgag cgtggtgcta ttttttcagg
      181 taaaataaaa catcacgaag attctcagtt taaaggagac cactatgttg aatgttatgc
      241 tgttttagat aatacggtta tagcaagaga tagaataaca gtccctatcg atccgttatg
      301 tggaaaagat tttatagagt agcatataat tgattcttaa ctggaatact ctctatctct
      361 ttacatcaag aaaatgacta aacagggaag tttgccttct tccctttttt tgttatacta
      421 gtagaagaaa aaaatagaaa gatttgtggg agtgaaaaag tccgggggac tttttcagct
      481 tgagccaaga aattcgagag cgaggaaagt ccgggggact ttttcagcct gagccaagaa
      541 attcgagagc gaagtaagtc caatggactt tttcagcctg agccaagaaa ctcgaaagct
      601 cgtaagtctg attggctttt tcaatgtgaa tcttaacttc acactcccaa agaggtatta
      661 gtgtcgtgtc tcaatcttat atcaatgtta tcggtgctgg tttggcaggt tctgaagcag
      721 cttaccaaat cgcagagcgt ggtattccag ttaaactata tgaaatgcgt ggtgtcaagt
      781 cgactcccca gcataaaaca gacaattttg ctgagttggt ttgttccaat tctttgcgtg
      841 gggatgcttt gacaaatgca gttggtcttc tcaaggaaga aatgcgtcgc ttgggttctg
      901 ttatcttgga atctgctgag gctacacgtg ttcctgcagg tggtgccctt gcagtggacc
      961 gtgatggttt ctctcaaatg gtgaccgaaa aagttgccaa ccaccccttg attgaagtgg
     1021 ttcgtgatga aattacagaa ttgccgacag atgttattac ggttatcgct actggtcctt
     1081 tgacaagtga tgccttggct gaaaagattc atgcccttaa tgacggtgat ggtttttatt
     1141 tctacgatgc ggcagcgcct attatcgatg tcaacactat cgatatgagc aaggtctacc
     1201 tcaaatcacg ttatgataag ggagaagcgg cctacctcaa tgcccctatg accaagcaag
     1261 aatttatgga tttccatgaa gctttggtca atgcagaaga agcaccgctt aattcttttg
     1321 aaaaagaaaa gtactttgaa ggctgtatgc ctatcgaagt catggccaaa cgtggcatta
     1381 aaactatgct ttatggccct atgaagccag tcggtcttga gtacccagac gactatacag
     1441 gacctcgtga tggagaattt aaaacacctt atgcggttgt gcaacttcgt caggacaatg
     1501 cagctggtag cctctacaat attgttggtt tccagaccca cctcaaatgg ggagaacaaa
     1561 agcgtatctt ccaaatgatt ccgggtcttg aaaatgcaga gtttgtccgt tatggtgtca
     1621 tgcatcgcaa ttcttacatg gattcaccaa atcttcttga gcagacttac cgttctaaga
     1681 aacaaccaaa tctcttcttt gctggtcaga tgacgggggt ggaaggctat gttgagtcgg
     1741 cggcttcagg cttagttgcg ggaattaacg cagctcgtct cttcaaggaa gaaagcgagg
     1801 ctattttccc cgagacgaca gcgattggaa gcttagctca ttacattacc catgccgaca
     1861 gcaaacattt ccaaccaatg aatgtcaatt ttgggatcat caaggagttg gaaggcgagc
     1921 gtatccgtga taagaaggct cgttatgaaa aaattgcaga gcgtgccctt gccgacttag
     1981 aggaattttt gactgtctaa tttttttgaa agaattgctc atgatactat aaaaatctta
     2041 gaaattgtga taaaataggt aggatgaaag aaggagagtg aaaatggcga atcccaagta
     2101 taaacgtatt ttaatcaagt tatcaggtga agcccttgcc ggtgaacgtg gcgtagggat
     2161 tgatatccaa acagttcaaa caatcgcaaa agagattcaa gaagttcata gcttaggtat
     2221 cgaaattgcc cttgttattg gtggaggaaa tctctggcgt ggagaacctg cagcagaagc
     2281 aggtatggac cgtgttcagg cagattacac tggaatgctt gggactgtta tgaatgctct
     2341 tgtgatggca gattcattgc aacaagttgg ggttgatacg cgtgtacaaa cagctattgc
     2401 tatgcaacaa gtggcagagc cttatgtccg tggacgtgcc cttcgtcacc ttgaaaaagg
     2461 ccgtatcgtt atctttggtg ctggaattgg ttcaccatac ttctcgacag atacaacagc
     2521 ggcccttcgt gcagctgaaa tcgaagcgga tgccatcctc atggctaaaa atggtgtcga
     2581 tggtgtttac aatgccgatc ctaagaaaga taagacagct gttaagtttg aagaattgac
     2641 ccaccgtgac gttatcaata aaggtcttcg tatcatggac tcaacagctt caaccctctc
     2701 aatggacaac gacattgact tggttgtctt caacatgaac caatcaggca acatcaaacg
     2761 tgtcgtattt ggtgaaaata tcggaacaac agtttcaaat aatatcgaag aaaaggaata
     2821 agaaagaata tggctaacgc aattattgaa aaagctaaag agagaatgac ccagtctcac
     2881 caatcacttg ctcgtgaatt tggtggtatc cgtgctggtc gtgccaatgc aagcttgctt
     2941 gaccgtatac atgtagaata ctatggagtt gaaactcctc ttaaccaaat cgcttcaatt
     3001 acgattccag aagcgcgtgt tttgttggta acaccatttg acaagtcttc attgaaagac
     3061 atcgaacgtg ccttgaacgc ttctgatctt ggtatcacac cagctaatga cggttctgtg
     3121 attcgcttgg ttgtcccagc tcttacagaa gagactcgtc gtgaccttgc taaagaagtg
     3181 aagaaggtcg gcgaaaatgc taaagtggct gtccgcaata tccgtcgcga tgctatggac
     3241 gaagctaaga aacaagaaaa agcaaaagaa atcactgaag acgaattgaa gactcttgaa
     3301 aaagacattc aaaaagtaac agacgatgct gttaaacaca tcgacgatat gactgccaac
     3361 aaagagaaag aacttttgga agtctaaaaa taaacagaaa aactcagttg gcattgctgg
     3421 ctgagtttta ttcgaaagaa ggaaatatga atacaaatct tgcaagtttt atcgttggac
     3481 tgatcatcga tgaaaacgac cgtttttact ttgtgcaaaa ggatggtcaa acctatgctc
     3541 ttgctaagga agaaggccaa catacagtag gggatacggt caaaggtttt gcatacacgg
     3601 atatgaagca aaaactccgc ctgacaagct tagaagtgac tgccactcag gaccaatttg
     3661 gttggggacg tgtcacagag gttcgtaagg acttgggtgt ctttgtggat acaggccttc
     3721 ctgacaagga aatcgttgtg tcactcgata ttctccctga gctcaaggaa ctctggccta
     3781 agaagggcga ccaactctac atccgtcttg aagtggataa gaaagaccgt atctggggtc
     3841 tcttggctta tcaagaagac ttccaacgtc ttgctcgtcc tgcctacaac aacatgcaga
     3901 accaaaactg gccagccatt gtttaccgtc tcaagctatc aggaactttt gtttacctac
     3961 cagaaaataa tatgcttggt tttattcatc ctagcgagcg ttacgcagag ccacgtttgg
     4021 ggcaagtatt agatgcgcgc gttattggtt tccgtgaagt ggaccgcact ttgaacctct
     4081 ccctcaaacc acgctccttt gaaatgttgg aaaacgatgc tcagatgatt ttgacttatt
     4141 tggaaagcaa tggcggtttc atgaccttaa atgacaagtc atctccagac gacatcaagg
     4201 caacctttgg catttctaaa ggtcagttca agaaagcttt aggtggtctt atgaaggctg
     4261 gtaaaatcaa gcaggaccag tttggtacag agttgattta gggaggctta tgagaaaatc
     4321 attttacact tggctcatga ccgagcgcaa tcctaaaagt aacaatccca aagcaatttt
     4381 ggcagacctc gcttttgaag aggcagcttt tccaaaacat acagatgatt ttgatgaggt
     4441 cagtcgcttt ttggaggagc atgccagttt ctcttttaac ctaggagatt ttgacagcat
     4501 ttggcaggaa tatctagaac actagcattt attcattggg tttgggctag taatttctcc
     4561 atccctctgc tataataaaa agaaataaaa ggattagaga ggttctttat ttgaaggaac
     4621 attcaataga cattcaactg agtcatccag atgacctgtt tcatcttttt ggttccaatg
     4681 aacgccatct tcgtttgatg gaagaagagc ttgatgttgt gattcatgct cgtacggaga
     4741 ttgtccaggt tttgggagaa gagtctgctt gcgaggaagc ccgtcaggtt attcaagctc
     4801 tcatggcctt ggtaaatcgt gggatgaccg ttggtacgcc agatgtagtg acggctatta
     4861 gtatggtcaa aaatgatgaa attgacaagt ttgtcgccct ttacgaagaa gaaatcatca
     4921 aggataatac tgggaagcct atccgcgtca aaaccttagg tcaaaaactt tatgtggaca
     4981 gtgtcaaaca gcatgatgtg acctttggaa ttgggccagc aggtacaggg aagaccttcc
     5041 ttgcagtgac cttggcagtg actgccctta aacgtgggca agtcaagcga attatcctaa
     5101 ctcgtccagc ggtggaagcg ggagagagtc ttggatttct tccgggtgat cttaaggaga
     5161 aggtggatcc ttaccttcgt cctgtttacg atgccttgta tcaaattctt gggaaagacc
     5221 aaacgactcg tctcatggag cgtgaaatta tcgaaattgc gccccttgcc tatatgcgtg
     5281 gccggacctt ggatgatgcc tttgtcattc tcgatgaggc gcaaaacacg accatcatgc
     5341 agatgaagat gttcttgacg cgtttaggct ttcattctaa gatgattgtc aatggagata
     5401 tcagtcagat tgacctgcca cgtaatgtca agtccggttt gattgatgct caagagaaac
     5461 tcaagaacat ccatcagatt gactttgttc atttttcagc caaggatgtg gttcgccatc
     5521 cagttgtcgc tcagattatc cgagcctatg aatattctac tgaagttgca cacgactgat
     5581 tttgaggaag ttcgcctgca aaagaatata cttttgagag aggaaaatcc agttgtatag
     5641 gctaaaggtt tgagacaacg attaggcacg atggaaagaa cttttatgtg gctgatgacg
     5701 atcagtgcat cttcctgtgt cataatcaca gggcacaaga aagtaggaat ttgaaaagat
     5761 gattgaccaa ctatctaagt attacagttg taggatacta actgaaaagg atattccaag
     5821 tattttatct ttatatgaaa gtaatcctct gtattttcag cattgtccac cagagccaaa
     5881 ttttgcaact gtaaaagagg acatgctttg tctacctgaa ggtaaagcta aggctgataa
     5941 gttttttgtt ggattttgga atggctctga ccttgtggct gttatggatt ttgtctatgc
     6001 atatcctgat gaggagactg tttttattgg tttgtttatg gttgatcaag cctatcagag
     6061 gaaagggatt ggtagtcata ttgtgacaga agcactagct tattttgcta agaactttcg
     6121 aaaggcacgt ttggcttatg ttaagggaaa tccgcaatct cagcattttt gggaaaagca
     6181 gggctttaaa tcaattggat gcgaggttaa gcaagaactc tatacggttg ttatcgctga
     6241 acagagccta gaagattaga aatggcatca agtaagaact atttggaatt tgttttggaa
     6301 caattatcag gattagatga tgtgacttac cgttccatga ttggggagta tattctttac
     6361 ttccgcggca agattattgg cggcatttat gacgatcgct ttttagttaa acccgtgcaa
     6421 gcagtcttag ataagattga ccaatcttct tttgagtttc catacaaagg tgccaaagaa
     6481 atgatttgag tggaagaact tgataataag atgtttctat aagacctgat tttagctatg
     6541 tataaccaac tgccaacgcc caaacctaaa aagaaaaagc aagggtgaac gaagtaaaaa
     6601 agaagtctgc taaggccctg tctttgcacg ggtaaaattt tatatataaa aagaagctgg
     6661 gactaaagag ctcagcttcc tttggtttat ataattgtca ttacaagacg aagtggttgg
     6721 gcgaaactct gttgacttta ttcaatttag agtttcttat gcacaattga gtctggaacg
     6781 aaagtctcca gttgcaaagt atacagtaca ataaaccaac gatgtaatag ctgatgacac
     6841 aaagcacagt gggtaggact tgcgaagtca cccttttctt ttcaaaattt atactaaatc
     6901 attgatatca gtgtagtcac gattaagtcc ttgagcaact ggtaggctag tcaagtaacc
     6961 ttgataagtg gtcacacctt gacgcaagcc ttcatcttca gagattgctt gtgcgaatcc
     7021 tttgccagcc aaagcttcga tataaggaag agtgacattg gttagggcga tggttgaagt
     7081 gcgggcaacc gcaccaggga tattggcaac ggcatagtgg agaacaccgt gtttttcata
     7141 gacgggttca tcgtgcgttg tcacacggtc agctgtttcg ataacgccac cttggtcaac
     7201 agcaacgtca acgatacaga gcctggacgc atttgtttga ccatctcatc tgtcaccaat
     7261 tccggtgctt ttgcaccagg gatgagaatg gctccaatca ccacatcagc atctctcaca
     7321 cttgcttcaa tgttgaatga attagatata atagtttgaa tttgacttcc aaagacttct
     7381 tctagaactg agagacgctt ggcactaata tctaaaatag tcacttgagc accaagacca
     7441 agggcgatgc gggcagcatg tgtaccgacg acaccatcac cgatgatagt tacttttcct
     7501 tttggaacac ctggtacacc accaagtaga acaccagagc caccagcttg cttagtaagg
     7561 aagtgagctc cgatttgaac agccatacga cctgcaacct cactcatagg aacgaggagc
     7621 ggtagttgtc cttgattgtc acgaacagtt tcataggcaa ttcctgttgt ttttgctgct
     7681 aacatagcat ctgctaattc tggagcagcg gccatgtgca agtaggtgaa gagaagaaga
     7741 tcgtcgcgca agtaaccgta ttcagaactt aaaggttctt ttactttcac aaccaactct
     7801 gctgcccaag cttcaccagc agtagcgaca atctcagctc cttgcttttg atagtcagca
     7861 tcagtaaagc cagaaccgag accagcattt gtttcgataa ggacacgatg accacgacta
     7921 actaagctat gaacacctgc aggtgtgagg gcgacacggt tttcgttatt tttaatttct
     7981 tttgggattc cgattaacat tgagataacc tacctttcaa ttgacggtct tgttttggtt
     8041 gtcacattcc agttcataaa tcaaaaatgt gacggtttca ttgtatatga aaccgcttca
     8101 aaaatcaaga aaaacttgtc atccaaattt ttttatgcta gactagtgaa aatcaagctc
     8161 taatggaggg aaaagtatgg aatcaatatt tgtgaaattt gcccagtatc cgtctataga
     8221 aacggagcgt ttattgctta gacctgtaac tttggatgat gcggaagcaa tgtttgacta
     8281 tgcctcggac aagggtaata cacgttacac ttttccaacc aatcaaagct tggaagaaac
     8341 caagaataac attgctcagt tctacttggc taatcccttg ggacgttggg ggattgaatt
     8401 aaaagataac ggcaagttta tcggaactat tgacttacac aagattgatc ctgttcttaa
     8461 gaaggcagct attggctaca ttatcaataa aaagtattgg aatcaaggat taacgacaga
     8521 agccaatcgt gctgtgattg agctagcttt tgagaagata gggatgaata agttgactgc
     8581 ccttcacgat aaggctaatc ccgcgtcagg aaaggtcatg gagaaatcag gcatgcgttt
     8641 ttcccatgca gaaccatatg cttgtatgga ccagcatgaa aaaggccgaa tcgtgacaag
     8701 agttcattat gtcttgacca aggaagacta ttttgcaaat aaataagcag ttgaaaagaa
     8761 atttttcgac tgttttttct tcctcttacg aataatctaa gagaggagaa aatatggaag
     8821 caattatcga gaaaatcaaa gagtataaaa tcatcgtcat ctgtactggt ctgggcttgc
     8881 ttgtaggagg atttttcctg ctaaagccag ctccacaaac atctgtcaaa gagacgaatt
     8941 tgcaggctga agttgcagct gtttccaagg actcatcgac cggaaaggaa gtgaacaagg
     9001 aagagaagga agaaccagtt gaacaagatc taatcacagt agatgtcaaa ggtgctgtca
     9061 aatcgccagg gatttatgac ttgcctgtag gtagtcgagt caatgatgct gttcagaagg
     9121 ctggtggctt gacagagcaa gcagacagca agtcgctcaa tctagctcag aaagttagtg
     9181 atgaggctct ggtttacgtt cctactaagg gagaagaagc agttagtcaa cagactggtt
     9241 cggggacagc ttcttcaaca agcaaggaaa agaaggtcaa tctcaacaag gccagtctgg
     9301 aagaactcaa gcaggtcaag ggactgggag gaaaacgagc tcaggacatt attgaccatc
     9361 gtgaggcaaa tggcaagttc aagtcagtag acgagctcaa gaaggtctct ggcattggtg
     9421 ccaagaccat agaaaaactt aaagactatg ttacagtgga ttaagaattt ctctattccc
     9481 ctaatttacc tgagttttct attactatgg ctttactacg ccattttctc agtatcctat
     9541 tttgctttgt tgggttttgt ttttctgcta gtctgcctct ttatccaatt tccttggaaa
     9601 tcagcaggta aagttctagt gatttgtgga gtctttggct tctggtttct gtttcaaact
     9661 tggcaacaga gtcaagtgag tcaaaatttg gtggattctg ttgaaagggt acggatttta
     9721 ccagacacta ttaaggttaa cggtgacagt ctgtcctttc gtggtaagtc tgatggtcgt
     9781 gctttccaag tctattataa actccagtcc gaggaggaga aagaagcctt tcaagcttta
     9841 actgaccttc atgagatagg actagaaggg aagctttcgg agccagaagg gcagagaaat
     9901 tttggtggct ttgactacca aggctatctg aagactcagg gaatttacca gacactcaat
     9961 attaaaagaa tccagtcact ccaaaaggtt ggcagttggg atataggtga aaacctgtcc
    10021 agtttacgtc gaaaggctgt ggtttggatt aagatgcact tcccagaccc tatgcgcaat
    10081 tacatgacag gactcttgct aggacatctg gacaccgatt ttgaggagat gaatgagctt
    10141 tattccagtt taggaattat tcaccttttt gccttgtcag gtatgcaggt agggtttttc
    10201 atggacggat ttaagaaact acttttacga ttgggcttga cacaagaaaa gttgaagtgg
    10261 ctgacttatc ccttttccct tatctatgcg ggactaactg gattttcagc atcggttatt
    10321 cgcagtctct tgcaaaagct actggctcaa catggggtta agggcttgga taattttgcc
    10381 ttgacggtgc ttgtcctctt tattgtcatg ccaaactttt tcttgacagc aggaggagtc
    10441 ttgtcctgtg cttatgcttt tatcctgacc atgaccagca aagaagggga ggggctcaag
    10501 gctgttacta gtgaaagtct agtcatctcc ttgggcatat tgcccattct atccttctat
    10561 tttgcggaat ttcaaccttg gtctatcctt ttgacctttg tcttttcctt tctttttgac
    10621 ttggtcttct taccgctctt gtctatctta tttgtccttt cctttctcta tccagtcatt
    10681 cagctgaact ttatctttga atggttagag ggcattattc gcttggtctc gcaggtggca
    10741 agtagaccgc ttgtctttgg acaacccaat gaatggcttt taatcctatt gttaatttct
    10801 ttggctttgg tctatgattt gaggaaaaac attaaaaagc taacggtatt gtgcttattg
    10861 attacagggc tctttctcct gaccaagcat ccactggaaa atgaaatcac catgctggat
    10921 gtggggcaag gagaaagtat tttcctacgg gatgtaactg ggaaaaccat tctcatagat
    10981 gtaggtggta aggcagaatc ttataagaaa atcaaaaaat ggcaagaaaa gatgacgacc
    11041 agcaatgccc agcgaagctt gataccctat ctcaaaagtc gaggagtagc taagattgac
    11101 cagctaattt tgactaacac ggacaaggag catgttggag atttgtcaga gatgaccaag
    11161 gctttccatg taggggagat tctagtatca aaagacagtc tgaaacagaa ggaatttgtg
    11221 gcagaactac aggcgactca aacaaaggtg cgtagtatga tagtagggga gaacttaccc
    11281 atttttggaa gtcagttaga agttctatct ccaaggaaaa tgggagatgg aggacacgat
    11341 gataccctag ttctgtatgg gaaattcttg gataagcaat ttctcttcac gggaaatttg
    11401 gaggagaaag gagagaagga cttgctgaag cactatccag acttgaaagt aaatgttttg
    11461 aaagctagcc aacatggcaa taaaaaatca tcaagtccag cctttctaga aaaactcaaa
    11521 ccagagctta ctcttatctc agttggaaag agcaatcgaa tgaaactccc ccatcaggaa
    11581 acattgacac gactggaagg tatcaatagc aaagtttatc gaactgacca gcaaggagct
    11641 atacgtttta aggggttgga tagttggaaa atcgaaagtg ttcgatagga aggataaatg
    11701 ttgtagatta gtgaaataaa ctaaaaattt gttgcataat aatgataaaa acggcataat
    11761 gaaaacgtat tcaatattga ggatataaaa tcattaaaaa tcagcaaaag ttgttttagt
    11821 tagttagttt ataatctatt ggtcttcttc agtccagtgt atctgctgtg acagtcacta
    11881 aaagttacaa gtatgattgg aatacggttt tggaatatag taccaactat cacgaccatc
    11941 agtatgcttg gattccggaa tggtctcgtt attacagcta ttctgagtat aaagttggcg
    12001 gaggctggaa ctacgctcgt tatgaggtca taaactacta tactggaggt tattaatcct
    12061 taaagagtga gaaaaggagg gctggatatg ttaaatctta ctcatgttac cttaaaaacg
    12121 cgacaagtca tcttgcaaga tgcggatttt acctttaaaa agggtaggat ttatggcctt
    12181 cttgctatca atggctcggg aaagacgaca ctattccgag ctatgagcaa gttgcttccc
    12241 cttagtagtg gacacatcgc agttcctcct tctttgtttt attatgagag cgttgaatgg
    12301 ctggatggaa acttaagtgg gatggactac cttcgtctca taaaaaacat ctggaagtca
    12361 gacctaaact tgagagatga aatcgcctac tgggaaatgg ctgactatat cagtcttccc
    12421 atccgcaagt attccttagg gatgaagcaa cgcttggtga ttgctatgta ttttctcagt
    12481 caggccaaat gctggctcat ggatgagatt acaaatggct tagacgagta ttatcgacag
    12541 aagttttttg ataggctagc acaaatcgat agacaagaac agctggttct tttaagttcc
    12601 cactataagg aagagttggt tgatatctgc gatagagtag taaccattca tcaggggcag
    12661 atagaagagg tttagtttat gaaagatgtt agtctatttt tattgaaaaa agttttcaaa
    12721 agtcgtttaa actggattat cttagcttta tttgtatctg tactcggtgt taccttttat
    12781 ttaaatagtc agactgcaaa ctcacacagc ttggagagca ggttggaaag tcgcattgca
    12841 gccaacgaga gggctatcaa tgaaaatgaa gagaaactct cccaaatgtc tgataccagc
    12901 tcggaggaat accagtttgc taaaaataat ttagacgtgc aaaaaaatct tttgacgcga
    12961 aagacagaaa ttctaacttt actaaaagaa gggcgctgga aagaagccta ctatctgcag
    13021 tggaaagatg aagagaagaa ttatgaattt gtatcaaatg acccgactgc tagctctggc
    13081 ttaaaaatgg gggttgaccg cgaacggaag atttaccaag ccctgtatcc cttgaacata
    13141 aaagcacata ctttggagtt tccgacccac gggattgatc agattgtctg gattttagag
    13201 gttatcatcc caagcttgtt tgtggttgcg attattttta tgctaacaca actatttgca
    13261 gaaagatatc aaaatcatct ggacacagct cacttatatc ctgtttcaaa agtgacattt
    13321 gcaatatcct ctcttggagt tggagtggga tatgtaactg tgctgtttat cggaatctgt
    13381 ggcttttctt ttctagtggg aagtctgata agtggttttg gacagttaga ttatccctac
    13441 ccaatttata gcttagtgaa tcaagaagta actattggga aaatacaaga tgtattattt
    13501 cctggcttgc tcttagcttt cttagccttt atcgtcattg tggaagttgt gtacttgatt
    13561 gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt cactcattgg gattgttggc
    13621 ttattgtttg gcatccaaac aattcagcct cttcaaagga ttgcacatct gattcccttt
    13681 acttacttgc gttcagtgga gattttatct ggaagattac ctaagcagat tgataatgtc
    13741 gatctaaatt ggagcatggg aatggtctta cttccttgcc tgattatctt tttgctattg
    13801 ggaattctat ttattgaaag atggggaagt tcacagaaaa aaagaatttt ttaatagatt
    13861 ctagctttcc tataggtagg gaaaataagt aaaaactaac atagagaggg aatcaacttg
    13921 attctctctt tttgattcga aaaccaaacc aaaatacaaa cacaaacttt tcaaaaaata
    13981 actttttatc ttgacaagag ctagaaaact tggtatcata taaaagttga gaaaagcaga
    14041 agtgagagct tctcgccttg tgacattaag ttgcctggcc ctacggatga aaagtttcga
    14101 agaaacgcta tcataacgtg cgggcttgta tatttacgag tccgctattg tttttctcta
    14161 ataaaacaaa agaggtgaaa accatagcaa agcaagactt attcatcaat gatgagattc
    14221 gtgtacgtga agttcgcttg attggtcttg aaggagaaca gctaggcatc aagccactca
    14281 gtgaagcgca agctttggct gataacgcta atgttgacct agtattgatt caaccccaag
    14341 ccaaaccgcc tgttgcaaaa attatggact acggtaagtt caaatttgag taccagaaga
    14401 agcaaaaaga acaacgtaaa aaacaaagcg ttgttactgt gaaagaagtt cgtctaagtc
    14461 caactattga caagggtgac tttgatacaa aacttcgtaa tgcacgtaag ttccttgaaa
    14521 aaggaaataa agttaaggta tctattcgct ttaagggtcg tatgattacc cataaagaga
    14581 ttggtgcaaa agttttagcc gagtttgctg aagcaactca agatattgcc atcatcgaac
    14641 aacgtgctaa aatggatgga cgtcaaatgt tcatgcaatt ggcgccagcg actgacaaaa
    14701 aataattgtc agaaagttaa ataaaggaga aaaaattatg ccaaaacaaa aaacacaccg
    14761 cgcatcagct aaacgtttca aacgtacagg ttctggtgga cttaaacgtt tccgtgctta
    14821 cacttctcac cgtttccacg gaaaaactaa gaaacaacgt cgtcatcttc gtaaagcatc
    14881 tatggtgcat tcaggagatt acaaacgtat caaagcaatg cttactcgct tgaaataata
    14941 gcttgactgt aagtaaacaa ttctaggaaa tatttggagg aaataaaaca tggcacgtgt
    15001 taaaggtggc gttgtatcac gcaaacgtcg taaacgtatt cttaaattag caaaaggtta
    15061 ctatggagct aaacacatct tgttccgtac tgcaaaagaa caagtaatga actcttacta
    15121 ctatgcatac cgtgaccgtc gtcagaaaaa acgtgacttc cgcaaattgt ggatcactcg
    15181 tatcaatgcg gcagctcgta tgaacggact ttcatactca caattgatgc atggtttgaa
    15241 attggctgag atcgaagtta accgtaaaat gcttgctgac ttggctgtta acgatgcagt
    15301 agctttcaca gctcttgcag atgcagctaa agcaaaactt ggtaaataac aactgatgag
    15361 actggaacag gattgtccag tctttttaaa aataaaggag aaaaatatgg cttcaaaaat
    15421 gctacacact tgcttacgag tagaaaatct tgaaaaatca atcgcatttt atcaagatgc
    15481 ttttggtttt aaagaattgc gtcgcagaga ttttccagac catgccttca cgattgtcta
    15541 tctaggtctt gagggtgatg actatgagtt ggagttgact tataactacg atcacggtcc
    15601 gtatgtggtt ggtgatgggt ttgcccatat cgccctcagt acacctgatc ttgaggcact
    15661 tcatcaagaa cacagtgcaa aaggctatga agtgactgag ccaaatggtc taccaggaac
    15721 tacaccaaac tattactttg tcaaagaccc tgatggatat aaggtcgaag tcattcgtga
    15781 aaaataattt cgtgcaagtt aagtagaata ttcgtttttt acttgacttt ttttagctga
    15841 aagagtatac taataaaaat tcaaccttta aggggagtcc agagagactc acaaggtgtc
    15901 agataaaaga atagtgcaat tttctagagg agactttttg agtgtgctct cttgtgttgt
    15961 acgattttaa ctgaggcctt gcactagcaa ggtcttttct ttatctggtc cccttaaaat
    16021 ttaaggagga aaagttatga atcccacatg taagaagcgt ttgggtgtca ttcggttgga
    16081 aaccatgaag gtggttgcac aagaggaaat cgcgccagca atctttgaat tagtcctaga
    16141 aggagaaatg gttgaagcca tgcgagcagg ccaatttctt catctgcgtg taccagacga
    16201 tgcccatctt ttacgtcgtc ctatttcaat ttcgtctatt gacaaggcaa acaagcagtg
    16261 tcacctcatt tatcggattg agggagctgg gactgcaatt ttttcaacct taagtcaggg
    16321 agacactctt gatgtgatgg ggcctcaggg aaatggtttt gacttgtctg accttgatga
    16381 gcagaatcag gttctccttg ttggtggtgg gattggtgtt ccacccttgc ttgaggtggc
    16441 caaggaattg catgaacgtg gagtgaaagt agtgacagtc ctcggttttg ctaataagga
    16501 tgctgttatt ttgaaaacgg aattggctca gtatggtcag gtctttgtaa cgacagatga
    16561 tggttcttat ggcatcaagg gaaatgtttc cgttgttatc aatgatttag atagtcagtt
    16621 tgatgctgtt tactcgtgtg gggctccagg aatgatgaag tatatcaatc aaacctttga
    16681 tgatcaccca agagcctatt tatctctgga atctcgtatg gcttgtggga tgggagcttg
    16741 ctatgcctgt gttctaaaag taccagaaag cgagacggtc aaccaacgcg tctgtgaaga
    16801 tggtcctgtt ttccgcacag gaacagttgt attataagga gaaaattatg actacaaatc
    16861 gattacaagt gtctctacct ggtttggatt tgaaaaatcc gattattcca gcatcaggtt
    16921 gttttggctt tggacaagag tatgccaagt actatgattt aaacctttta ggttctatta
    16981 tgatcaaggc gacaaccctt gaaccacgtt ttgggaaccc aactccaaga gtagcagaga
    17041 cgcctgctgg tatgctcaat gcaattggct tgcaaaatcc tggtttagag gttgttttgg
    17101 ctgaaaagct accttggctg gaaagagaat atccaaatct tcctattatt gccaatgtag
    17161 ctggtttttc aaaacaagag tatgcagctg tttctcatgg gatttccaag gcaactaatg
    17221 taaaagctat cgagctcaat atttcttgtc ccaatgttga ccactgtaat catggacttt
    17281 tgattggtca agatccagat ttggcttatg atgtggtgaa agcagctgtg gaagcctcag
    17341 aagtgccagt ttatgtcaaa ttaaccccga gtgtgaccga tatcgttact gtcgcaaaag
    17401 ctgcagaaga tgcgggagca agtggcttga ccatgatcaa tactctggtt ggaatgcgct
    17461 ttgacctcaa aaccagaaaa ccaatcttgg ccaatggaac aggtggaatg tcaggtccag
    17521 cagtctttcc agtagccctc aaactcatcc gccaagtagc ccaaacaaca gacctgccta
    17581 tcattggaat ggggggagtg gattcggctg aagctgccct agaaatgtat ctggctgggg
    17641 catctgctat cggagttgga acagctaact ttaccaatcc ttatgcctgc cctgacatca
    17701 tcgaaaattt accaaaagtc atggataaat acggtattag cagtctggaa gaactccgtc
    17761 aggaagtaaa agagtctctg aggtaaactg caatcaatct gttcttgatt ttttattagt
    17821 ttgtaatatg aatttaggag aattttggta caataaaata aataagaaca gaggaagaag
    17881 gttaatgaag aaagtaagat ttattttttt agctctgcta tttttcttag ctagtccaga
    17941 gggtgcaatg gctagtgatg gtacttggca aggaaaacag tatctgaaag aagatggcag
    18001 tcaagcagcg aatgagtggg tttttgatac tcattatcaa tcttggttct atataaaagc
    18061 agatgctaac tatgctgaaa atgaatggct aaagcaaggt gacgactatt tttacctcaa
    18121 atctggtggc tatatggcca aatcagaatg ggtagaagac aagggagcct tttattatct
    18181 tgaccaagat ggaaagatga aaagaaatgc ttgggtagga acttcctatg ttggtgcaac
    18241 aggtgccaaa gtaatagaag actgggtcta tgattctcaa tacgatgctt ggttttatat
    18301 caaagcagat ggacagcacg cagagaaaga atggctccaa attaaaggga aggactatta
    18361 tttcaaatcc ggtggttatc tactaacaag tcagtggatt aatcaagctt atgtgaatgc
    18421 tagtggtgcc aaagtacagc aaggttggct ttttgacaaa caataccaat cttggtttta
    18481 cataaaagaa aatggaaact atgctgataa agaatggatt ttcgagaatg gtcactatta
    18541 ttatctaaaa tctggtggct acatggcagc caatgaatgg atttgggata aggaatcttg
    18601 gttttatctc aaatttgatg ggaaaatagc tgaaaaagaa tgggtctacg attctcatag
    18661 tcaagcctgg tactacttca aatccggtgg ttacatgaca gccaatgaat ggatttggga
    18721 taaggaatct tggttttacc tcaagtctga tggcaaaatg gctgaaaaag aatgggtcta
    18781 cgattctcat agtcaagcct ggtactactt caaatctggt ggttacatgg cgaaaaatga
    18841 gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa aagctacaaa
    18901 tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg attcagatgg
    18961 tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg atagaaaaag
    19021 tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga aaacagaaga
    19081 tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg atggccaccg
    19141 tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc tttctgatat
    19201 ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt ttaagcttga
    19261 gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg aagaattgga
    19321 taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg gcgctacttt
    19381 taaggaagcc gaagaacatt accatatcaa tgctctttat ctccttgccc atagtgccct
    19441 agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct ttggcattac
    19501 agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg ataagggaat
    19561 tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa ctttccttgg
    19621 aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg gcgaaaaaat
    19681 tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt actataagtg
    19741 aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat caggattttt
    19801 tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt cctgtgtaag
    19861 tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca atcatatcta
    19921 cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct gctgcgtctg
    19981 tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt ccaggaatgt
    20041 ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat tcctcatttt
    20101 gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga tattgttcta
    20161 gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct gtttgaatca
    20221 attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg gtttctacac
    20281 tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag tatttgacag
    20341 cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg ggagtcagag
    20401 ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg ataacctggt
    20461 cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt tgacgaaatt
    20521 cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg tgtcggtttt
    20581 tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg acgcggtcgc
    20641 gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca agaggctctc
    20701 ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat ggcttggttt
    20761 cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc ctttccaatt
    20821 catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt gctgttagtt
    20881 cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga ttgagagatt
    20941 ttgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag ctattttgtg
    21001 aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg accagtagaa
    21061 tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg tctccaatct
    21121 cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc tcaatcgact
    21181 caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa ggttgggctg
    21241 gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg gcagaaagga
    21301 gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt tcaaaaggct
    21361 gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca actatgtggt
    21421 gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc atagtattat
    21481 atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt aaagagaaac
    21541 gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa agaaatgttg
    21601 caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga agacaaggag
    21661 atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctggg gtaccgtgac
    21721 accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga aattgccttt
    21781 gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga gtttgatgcc
    21841 tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggccga agaatatggt
    21901 cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca tattaacggc
    21961 tatgatcact atactccgga agaagaagcg gagatgttcg gtttacaaga agaaattttg
    22021 acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgacc tgatatccag
    22081 tttagaattt gccatcacag ggatttttac tgctatcaag gaagaacgca atatgcgaaa
    22141 acatgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg tgtcacgaat
    22201 cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa ttatcaattc
    22261 tgctatcgaa aatgtggtgg atttggccag tcactatcac ttttccatgc tggctaaaaa
    22321 tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag ccttaacagg
    22381 cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa gaggaaatta
    22441 tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg aagtcaacct
    22501 ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg cagacaacgc
    22561 gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt atcgacacac
    22621 cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct gcctacagta
    22681 cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg cgtggtaagg
    22741 gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt ttggtggtga
    22801 ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac ttccgtaatc
    22861 aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac gtgtctcgtc
    22921 tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg tctgatcaaa
    22981 tcacagacca tccagaccgt ttcttagttt cagaaatggt tcgcgagaaa gtcttgcacc
    23041 taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg aaacgagacg
    23101 aagagacaga caaggttcac atccgtgcaa ccatcatggt cgagcgcgat agccaaaaag
    23161 ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg gcccgtcgtg
    23221 atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag gtcaagaaaa
    23281 actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga gaatactaag
    23341 tagaggtggg ctcatgcctg cttcttgttt ttacagaagg aggacttatg cctgaattac
    23401 ctgaggttga aaccgtttgt cgttgcttag aaaaattgat tataggaaag aagatttcga
    23461 gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt caaagggaat
    23521 tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt ttttatctga
    23581 cagacaaggt tttgatttcc catttgcgga tggagggcaa gtatttttac tatccagacc
    23641 aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt ggcacgcttg
    23701 tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac cttttagacg
    23761 cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt gatttacagg
    23821 tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc ctagaccaga
    23881 ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga gctcaggttc
    23941 atccagctag atcttcccag actttgacag cagaagaagc gacagctatt catgaccaaa
    24001 ccattgctgt tttgagccag gctgttgaaa aaggcggttc caccattcgg acctatacca
    24061 atgcctttgg ggaagatgga agcatgcagg attttcatca ggtctatgat aagactggtc
    24121 aaggatgtgt acgctgtggt accatcattg agaaaattca actaggtgga cgtggaaccc
    24181 acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa tcactggggg
    24241 aattgcctct ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct ttcaagtagt
    24301 ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt ttgaggctct
    24361 agtacagcac ttttggcaag aaatcattct tgaaaacgga gaactcaatc gccctctcct
    24421 agctagtctc atcttttcaa atcctgatga acgagaatgg tctaagcaaa ttcaagggga
    24481 gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag aagagatttt
    24541 cttcatggat attcccctac tttttgagca ggactacagc gattggtttg ctgagacttg
    24601 gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg accagttgtc
    24661 caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa agaaagattt
    24721 ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc aagtgcatat
    24781 ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat ctgcgcattg
    24841 cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct tttatgccta
    24901 tcttcgtgga aaatctaggt gtagggagtg agcaagtcgc tttttatgca ggcttagcaa
    24961 tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt cttgctgaca
    25021 aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc actatgggag
    25081 gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta aacggtgtat
    25141 ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca aaggagaaat
    25201 caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta actggtccct
    25261 ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta ctggttggta
    25321 gttttctatt tttagctgct attttgacta tttgctttat caaggaagat tttcaaccag
    25381 tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa tatccctatc
    25441 ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa tcgattggcc
    25501 ctattttggc tctttatgta cgcgatttag ggcagacaga gaatcttctt tttgtctctg
    25561 gtttgattgt gtccagtatg ggcttttcca gcatgatgag tgcaggagtc atgggcaagc
    25621 taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat tcagtcatca
    25681 tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat cgtttcctct
    25741 ttggattggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc aaaatgactc
    25801 ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat ctgggaggtg
    25861 ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat gctgtctttt
    25921 atgcgacgag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa tttcgaacat
    25981 tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct cctcttgtgg
    26041 cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga ttgaggtttt
    26101 aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt agattttatg
    26161 gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa ccattttatt
    26221 agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa accaatccag
    26281 caatgtattt gatgccagtt caggtgattt gtttgaacgt agtaaagctc gcggttttga
    26341 agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca ttgccttagc
    26401 attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct ttgcctcttt
    26461 ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa aatctagaaa
    26521 gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt gactgttaat
    26581 gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt gattaaaacc
    26641 ttgtccttaa tggaaagaaa gcaccaaatt cgttttgaag aagatggtag tctgacatta
    26701 gaaattaaga aaaaacatga gattaccctc aaggggattt ttcatgccca taaaaatggc
    26761 tttggctttg ttagtctgga aggcgaggag gacgaccttt ttgtagggaa aaatgatgtc
    26821 aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc tgaccgcaat
    26881 aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt gacaacagtt
    26941 gtcgggcaaa tcgttctgga tcaggaaaaa cctaagtatg ctggctatat tcgttcaaaa
    27001 aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt agaaggaaca
    27061 gaagttctca aagtctttat cgataaatac ccaagcaaga aacatgattt ctttgtcgcg
    27121 agtgttctcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct tgaggtcttg
    27181 gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc agaaagtgtg
    27241 cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga tgaaattacc
    27301 tttaccattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat caaggctctg
    27361 aaaaatggca atctggagct tggggttcac atcgcagatg tttcttatta tgtgaccgag
    27421 gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt gacagaccga
    27481 gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa tccccaagtt
    27541 gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt ggtcaactat
    27601 accattacac aaacagttat caagaccagt tttcgtatga cctatagcga tgtcaatgat
    27661 atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtatc aagtatcgaa
    27721 ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg agctctcaat
    27781 tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt tgatatcgtt
    27841 cttcggcagc gtggtattgc cgagcggatg attgagtctt ttatgttgat ggctaatgaa
    27901 acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat tcacgaggag
    27961 cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg cttgcgcatt
    28021 tatggaactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg tgctgttgag
    28081 ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca gcaggctcgt
    28141 tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac tcactttacc
    28201 agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga ttacggccgt
    28261 tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac ccagtcttcc
    28321 aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa aaaggctgag
    28381 tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat tgtcaaattc
    28441 ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac taatctacct
    28501 gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc aggtatcact
    28561 ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat gactggagag
    28621 attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt gaaacagtct
    28681 agtcatagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga agacaagaga
    28741 aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa gaaaaaagga
    28801 aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa agggcgaggg
    28861 aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag atacgctaga
    28921 ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc gaattaatct
    28981 caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg ttcatatcgc
    29041 gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta aactcctgct
    29101 ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa tgaccttagt
    29161 tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac ttgccaaagg
    29221 gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc gagatatcgc
    29281 gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg aaaaattagt
    29341 tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagatg ttcagcaaaa
    29401 gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag ctctcaagtt
    29461 tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag caggggcaga
    29521 caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag atgatgtgga
    29581 atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat acaataccaa
    29641 tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga aagctttgga
    29701 tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt ttgatgtgac
    29761 ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg agcaggaaga
    29821 tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac aagaatatga
    29881 ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc cagctattat
    29941 tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt gtgccatgga
    30001 cacggaggat tatccttgct cggttaattt cccattcacc tttaaagaag gagaactggc
    30061 agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc atttgcaccg
    30121 tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag ctaagaaaat
    30181 caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt tacgaatgat
    30241 atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat tggtaaatgt
    30301 gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag gccagctcca
    30361 tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa aagactgtga
    30421 ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc tctatcactg
    30481 gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta aacagattgc
    30541 ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct tgcctcagaa
    30601 agtccttaaa gagcgaagtg agggatatcg tagtcagggt taccaagtac tgtggttgct
    30661 gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt ttctttattt
    30721 cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag ttttaagact
    30781 caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca aggaattttc
    30841 ctatggtcaa ggta
//
LOCUS       DAVBED010000022        30074 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBED010000022 DAVBED010000000
VERSION     DAVBED010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.022"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQ547_000996"
     CDS             51..1100
                     /locus_tag="VQ547_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2542857.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ547_000997"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ547_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2542858.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ547_000998"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ547_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2542859.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ547_000999"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ547_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2542860.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQ547_001000"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQ547_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2542861.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQ547_001001"
     CDS             8972..13363
                     /locus_tag="VQ547_001001"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2542862.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQ547_001002"
     CDS             13465..13728
                     /locus_tag="VQ547_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2542863.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQ547_001003"
     CDS             13721..13999
                     /locus_tag="VQ547_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2542864.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQ547_001004"
     CDS             14020..14172
                     /locus_tag="VQ547_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542865.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQ547_001005"
     CDS             14194..15435
                     /locus_tag="VQ547_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2542866.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQ547_001006"
     CDS             15445..15675
                     /locus_tag="VQ547_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2542867.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQ547_001007"
     CDS             15898..16620
                     /locus_tag="VQ547_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2542868.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQ547_001008"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQ547_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2542869.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQ547_001009"
     CDS             complement(18227..19138)
                     /locus_tag="VQ547_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2542870.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQ547_001010"
     CDS             complement(19162..19965)
                     /locus_tag="VQ547_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2542871.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ547_001011"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ547_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2542872.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ547_001012"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ547_001012"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2542873.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQ547_001013"
     CDS             complement(22573..23385)
                     /locus_tag="VQ547_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2542874.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQ547_001014"
     CDS             23575..24993
                     /locus_tag="VQ547_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2542875.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQ547_001015"
     CDS             25046..25753
                     /locus_tag="VQ547_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2542876.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQ547_001016"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQ547_001016"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2542877.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQ547_001017"
     CDS             26824..28146
                     /locus_tag="VQ547_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2542878.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQ547_001018"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQ547_001018"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2542879.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQ547_001019"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQ547_001019"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2542880.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQ547_001020"
     CDS             complement(29581..29898)
                     /locus_tag="VQ547_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2542881.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVBED010000023        29757 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBED010000023 DAVBED010000000
VERSION     DAVBED010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.023"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQ547_001021"
     CDS             132..494
                     /locus_tag="VQ547_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542882.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQ547_001022"
     CDS             902..1201
                     /locus_tag="VQ547_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542883.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQ547_001023"
     CDS             complement(1296..1733)
                     /locus_tag="VQ547_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542884.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQ547_001024"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQ547_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2708..3358)
                     /locus_tag="VQ547_001025"
     CDS             complement(2708..3358)
                     /locus_tag="VQ547_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2542885.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3470..4312
                     /locus_tag="VQ547_001026"
     CDS             3470..4312
                     /locus_tag="VQ547_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2542886.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4388..4825
                     /locus_tag="VQ547_001027"
     CDS             4388..4825
                     /locus_tag="VQ547_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2542887.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4893..5195
                     /locus_tag="VQ547_001028"
     CDS             4893..5195
                     /locus_tag="VQ547_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542888.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5286..6359)
                     /locus_tag="VQ547_001029"
     CDS             complement(5286..6359)
                     /locus_tag="VQ547_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2542889.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6515..7192
                     /locus_tag="VQ547_001030"
     CDS             6515..7192
                     /locus_tag="VQ547_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2542890.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7185..8159
                     /locus_tag="VQ547_001031"
     CDS             7185..8159
                     /locus_tag="VQ547_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2542891.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ547_001032"
     CDS             complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ547_001032"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2542892.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10209..10385)
                     /locus_tag="VQ547_001033"
                     /pseudo
     CDS             complement(10209..10385)
                     /locus_tag="VQ547_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10392..10532)
                     /locus_tag="VQ547_001034"
     CDS             complement(10392..10532)
                     /locus_tag="VQ547_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2542893.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10963..11163)
                     /locus_tag="VQ547_001035"
     CDS             complement(10963..11163)
                     /locus_tag="VQ547_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542894.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11402..11947
                     /locus_tag="VQ547_001036"
     CDS             11402..11947
                     /locus_tag="VQ547_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2542895.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ547_001037"
     CDS             12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ547_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2542896.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGSRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13258..13872
                     /locus_tag="VQ547_001038"
     CDS             13258..13872
                     /locus_tag="VQ547_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2542897.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14164..14913)
                     /locus_tag="VQ547_001039"
     CDS             complement(14164..14913)
                     /locus_tag="VQ547_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2542898.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15046..17382
                     /locus_tag="VQ547_001040"
     CDS             15046..17382
                     /locus_tag="VQ547_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2542899.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17484..18161
                     /locus_tag="VQ547_001041"
     CDS             17484..18161
                     /locus_tag="VQ547_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2542900.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18148..18945
                     /locus_tag="VQ547_001042"
     CDS             18148..18945
                     /locus_tag="VQ547_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2542901.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18962..20065
                     /locus_tag="VQ547_001043"
     CDS             18962..20065
                     /locus_tag="VQ547_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2542902.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20072..20263
                     /locus_tag="VQ547_001044"
     CDS             20072..20263
                     /locus_tag="VQ547_001044"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542903.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20366..21385
                     /gene="galE"
                     /locus_tag="VQ547_001045"
     CDS             20366..21385
                     /gene="galE"
                     /locus_tag="VQ547_001045"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2542904.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21387..22340
                     /locus_tag="VQ547_001046"
     CDS             21387..22340
                     /locus_tag="VQ547_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2542905.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22492..23157
                     /locus_tag="VQ547_001047"
     CDS             22492..23157
                     /locus_tag="VQ547_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542906.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23196..23297
                     /locus_tag="VQ547_001048"
                     /pseudo
     CDS             23196..23297
                     /locus_tag="VQ547_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23348..23554)
                     /locus_tag="VQ547_001049"
     CDS             complement(23348..23554)
                     /locus_tag="VQ547_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2542907.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23606..24082
                     /locus_tag="VQ547_001050"
     CDS             23606..24082
                     /locus_tag="VQ547_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2542908.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24091..24762
                     /locus_tag="VQ547_001051"
     CDS             24091..24762
                     /locus_tag="VQ547_001051"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2542909.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24893..25231
                     /locus_tag="VQ547_001052"
     CDS             24893..25231
                     /locus_tag="VQ547_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2542910.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25234..25863
                     /locus_tag="VQ547_001053"
     CDS             25234..25863
                     /locus_tag="VQ547_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2542911.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26103..27254
                     /locus_tag="VQ547_001054"
     CDS             26103..27254
                     /locus_tag="VQ547_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2542912.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27567..28316
                     /gene="truA"
                     /locus_tag="VQ547_001055"
     CDS             27567..28316
                     /gene="truA"
                     /locus_tag="VQ547_001055"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2542913.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28306..29079
                     /locus_tag="VQ547_001056"
     CDS             28306..29079
                     /locus_tag="VQ547_001056"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2542914.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29057..29518
                     /locus_tag="VQ547_001057"
     CDS             29057..29518
                     /locus_tag="VQ547_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2542915.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8719 a         5366 c         6692 g         8980 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt tttttcaaat attctaccac caaatgaaag
     2641 taaaataaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
     2701 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
     2761 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttaactt
     2821 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
     2881 cgtgcatccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
     2941 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
     3001 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
     3061 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
     3121 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
     3181 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
     3241 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
     3301 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
     3361 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
     3421 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
     3481 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
     3541 tcggcagcta ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
     3601 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
     3661 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca
     3721 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
     3781 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat
     3841 tagccatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
     3901 ggaatttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacacattca
     3961 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
     4021 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
     4081 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagatt acgatgtggc
     4141 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
     4201 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
     4261 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
     4321 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
     4381 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
     4441 cctcgagggg aagaaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
     4501 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
     4561 gcgtggaacg ggcggaacag atattgtcaa ggaccttaag gatattagtc ttttagatgt
     4621 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
     4681 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
     4741 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
     4801 tgcagagagt cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt
     4861 atgataaaat gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag
     4921 cctttatagt gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat
     4981 tatccctcat ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga
     5041 atgttcagtt agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa
     5101 gtggcatctt tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc
     5161 cccattatct ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact
     5221 tagaatgcac atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa
     5281 gagtattatc tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga
     5341 cccaaggttt ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg
     5401 tattcaagcg cctttaagga agccaagtca ttgatagagc taataccagc ctcaagaata
     5461 gtgccaaaga agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat
     5521 tctttaaagg ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag
     5581 tgcttgtcct caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta
     5641 ctctgaacga tgattttgtg agcaggaatt tccagcatca taccgataat ggaaccttgt
     5701 ggaatgaata tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct
     5761 tgatggagac caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc
     5821 tcaatttggc tagcagcata gatagcgaga tttcctccct tggaatgccc agctagaata
     5881 accttttgct taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga
     5941 gcaggaattt ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca
     6001 tctgtcccac gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca
     6061 aattgctttt gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg
     6121 aagcgcttgt gttgagccaa tttatctaat aattgaaggc gatttttgct agtaagcatg
     6181 gtgggctctc ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc
     6241 agattatcaa aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag
     6301 ggaaggtcgt aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata
     6361 agagctcctt tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc
     6421 ctgtttgcac tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga
     6481 aaaatctgtt ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga
     6541 tgatcaggtc attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt
     6601 cctggtagaa gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt
     6661 cctcatggat attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa
     6721 gatttccaag gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat
     6781 ggcaatcaat atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt
     6841 agctaaggtt cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct
     6901 ggaatatgct ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt
     6961 cttgaatttg accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa
     7021 catcgtagca cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga
     7081 taataccctc tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt
     7141 aggatttatc gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac
     7201 aattttttct agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg
     7261 catttcttgt cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact
     7321 ttttcttctt gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa
     7381 tgcaggtcta tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa
     7441 tagctttagc agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag
     7501 cagaaagaaa actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga
     7561 cccccattgc agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc
     7621 agctagaaca ggaaattttc aaaatcgact cttataccaa cctagtttta cagtacctgc
     7681 gtttagaaag tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca
     7741 aggaaataat tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac
     7801 atgaccttga taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa
     7861 tcatctcaaa cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc
     7921 aagagctttg tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat
     7981 ttgaacgtgg cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc
     8041 tttatctatc taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg
     8101 tcggaaaagg aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa
     8161 aatagatgag aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg
     8221 cgtgatttgt tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt
     8281 tgtgtttctt tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct
     8341 ccaacaatta attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt
     8401 ttttcattgc gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggctact
     8461 tcccaagcgt agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt
     8521 gccagccatg ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc
     8581 atagttgaga taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg
     8641 atgtatttga ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt
     8701 tcttcttttc caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct
     8761 tcaccttcgg cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt
     8821 tgggcatttt cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga
     8881 agagagaggc ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac
     8941 tgaagggcac gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg
     9001 ttgagtgaca tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg
     9061 tgcatcatac cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt
     9121 ttgaaaactt ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca
     9181 cccatgtcca tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg
     9241 taaagctcaa cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct
     9301 ttgtttacga tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat
     9361 ggcaaacctt gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta
     9421 cggtggtcac gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg
     9481 tcaaaccaag ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag
     9541 tacgcaccag ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga
     9601 ggtccacggc agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct
     9661 tctgagtgtt cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc
     9721 tcgtctttag tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt
     9781 tcttcttcga tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg
     9841 tagtagaaac catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga
     9901 cgagctgctt gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatctccg
     9961 tgatcaggtg tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg
    10021 agtttgccgt tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg
    10081 gcaatttcaa aagttgttac gccagattcg aattcacgaa tagcgccatc tgggaaagta
    10141 atgttaatca tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta
    10201 tcagcagact acttccaagt tctaacgttc aattgctttt ctttatcaga gaggaagttt
    10261 tccatttccg tcagaatatc tatatccaaa cgttgagaaa gttctaatag tcaccagata
    10321 ttttctgaaa gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt
    10381 gtcatcacca gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct
    10441 accgtccact tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc
    10501 caactgcgct ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac
    10561 atcctcgaaa ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg
    10621 acacctctga tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt
    10681 agtatcagtt tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga
    10741 ctaagtgact tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg
    10801 tgaaagtttt ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat
    10861 gcccaccaga gcaactgttt catagattag caagtaaatt agtataaaca caccaaaggt
    10921 tatgatagta aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa
    10981 acggtagcta tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt
    11041 gtttatatag agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata
    11101 aagtggccaa taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg
    11161 catgataatc acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat
    11221 agtatgttta aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa
    11281 tcatggttag ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt
    11341 gattattaag agtgtcacaa ttgttgtaac taaaataatt acaacaagag gggtataaaa
    11401 aatgaaacta gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc
    11461 agtcaaacga ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga
    11521 gtctattatt aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc
    11581 tgttatttca gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat
    11641 cgaactattt aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggatc
    11701 aggaagcctt tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc
    11761 tgaagaattt aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa
    11821 aaataatctc aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa
    11881 aacaggaaac tacattctag caggagaaat ttttactact aatgaaaaaa ggaataagcc
    11941 agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa ggtcatcata
    12001 taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa tgtttgacag
    12061 aaaatttaaa tcttggtaga atagggattg tcgtaaagac aaataacttc ttcttggtta
    12121 caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca tcatggcaat
    12181 ctcaaaagag aaaaaaaatg aaatcatcgc acaatatgca cgtcacgaag gtgatacagg
    12241 ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta atgaacacat
    12301 caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa tcggtagccg
    12361 tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg agttgatcaa
    12421 ctctctagga cttcgtcgct aattcaagat acaaaggctg tcaaaagcac aaagtaaaaa
    12481 taggaaaatt tacgaagaaa cttcagtttc taggagattt tatctttttt gccaagtgct
    12541 taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg ggtagctttt
    12601 ttgtgttgtc accttacctc gatatactca agtataatct ttggttacgg ttcctagcac
    12661 tgtaaggtaa aataaaccag cttttctccc ttcggggaga ttttttttgt ttcactgaaa
    12721 gtttcgtacg atcttcgcct cgtcgcctag tctataaacg atttatctag caagaatcat
    12781 gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa tgacacagtg ttcgatgagc
    12841 acaaggagtt tcatcttttt cactaggatt ttagcccgga ctcaaatcag ctctctgact
    12901 tcagagggct tttttattga ggttttatcg gtaacaattt tggagactac aaaaacctca
    12961 aacggtatca gctaattaca ccataaaggt gcgcagttac tcggcttttc aagccgagta
    13021 gttgtatgca agccccctag aagagcccac tctttacaaa gtaaagtata gtatgttata
    13081 ctttacatgg aagtagtcac tgaattccag ttagaaatta ctttgtaact acgttttgag
    13141 gaggagtaaa atgctttcct acgttcgata ttacccacta gcgatagcta aattaatgtg
    13201 tctgtgctct cctaaaatct gctgatttat tactgactaa tacaggagtt tttttttatg
    13261 ggacagacaa tcatatctgc tattggtgtt tatatttcca ccagtatcga ttatttaatt
    13321 attttaatta ttttatttgc acagctatca cagaataaac agaaatggca tatttatgcg
    13381 gggcaatatc taggcacagg cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt
    13441 aatttcgtgc ctgaagaatg gatggttgga ttgcttggtt taatccctat ctatttaggg
    13501 attcgctttg caattgttgg agaagatgcg gaagaagaag aggaagaaat tattgaaaga
    13561 ttagaacaaa gcaaggcaaa tcaactgttt tggacagtta cattgctgac aattgcgtct
    13621 ggcggagata atttaggtat ctatatacct tattttgctt cgttagattg gtcacagacc
    13681 ctcgtggcct tgcttgtgtt tgtaatcggc ataattatct tttgcgagat tagtcgggtg
    13741 ttatcttcta ttccgttaat attcgagaca attgaaaaat acgagcgaat cattgtgccc
    13801 ttagtattca ttctacttgg actatacatc atgtatgaaa atggcacgat agagactttt
    13861 ctgatcgtgt agattttttt gtttcactag gattttagtc cgagctcaaa tcagctctct
    13921 gattttcaga gggctttttc attgagtata aatggacaat cttaaagtta ctctattgta
    13981 gagtggcttt tgatttgatt aggagattct tataaatata gtaaaatgaa ataagaatag
    14041 gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt agaggtgtac
    14101 tattctagtt tcaatttgat atataaatga aaaccttagc tgtttggcca aggttcattt
    14161 cttctatgca agttcttctc ttttcttatc tgggttccag atgaagcttg cgataaagct
    14221 aaagatgatg gttaggatag cgagaataat agcaaggatg agggcaggga tgcggataaa
    14281 ccaccagagt ggatttggtt ttttatcatt gtgccattgt ttcgtttctt cgtccagacg
    14341 ttggaattct gtttgaatac gattggcgac tgtttcaatg ccttcatcat tcattttctt
    14401 gatatctgag atatcgattg gatttccaaa gttcatatcg acacgttcac ggctaatcaa
    14461 gcccttcaaa gtcatgggac cggtgtaggt aaccggcatg atacggacct tggccatttt
    14521 ggcaatcagt gctgcgcccc ccttgacatc gtttgagtgg cggctaccac ttggaaacat
    14581 gatgagagag cggtcacttt ttttgagaac gttgatagga tatttgatgg ctgaggcgct
    14641 gggattttca cggtcgatgg gaaaggcgcc acacatacga atccaccaac caaagatacg
    14701 gttggtaaag agttcttttt ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc
    14761 catataaaca ggatcccacc aggtacggtg aggcgcaact aaaatataat tttcatcttg
    14821 attaggaatt ttatcagtat tatgatagtg agcattgcca ttgatggacc ataagagcaa
    14881 tacaactaat ccacgcaaat aagtataaaa catgcgatct ccttcgattg ttttcttgtt
    14941 attattatac cttatcaaag gagggctggc aaacttttcc cttgactaga tgcatatttg
    15001 ggatgaaatt agaattctgt taaaaaaaat gatataatag aatttatgga taaaaataag
    15061 attatgggat taacccaaag agaaatcaag gaaagacagg ctgagggttt ggtcaatgac
    15121 tttaccgcat cagccagtac cagcacttgg caaatcgtta aacgaaatgt ctttaccctt
    15181 tttaacgctt tgaactttgc cattgctttg gcccttgcct ttgtgcaggc ttggagcaat
    15241 ctggtcttct ttgctgttat ctgctttaac gctttttctg ggattgtgac cgagctacga
    15301 gccaaacaca tggtggacaa gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt
    15361 gatggtcagg aagttgctct taatcctgaa gaattagtgc taggagatgt cattcgtttg
    15421 tctgcaggag agcagattcc tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat
    15481 gaagccatgt taacgggaga aagtgatttg gtgcaaaagg aagttgacgg cttacttttg
    15541 tcaggaagtt tcctagccag tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac
    15601 aactatgctg ccaaactcat gcttgaggct aagaccgtta aacccatcaa ctcccgtatc
    15661 atgaaatcgc tggacaagtt ggctggtttt actgggaaga ttatcattcc ctttggtctg
    15721 gctctcttgc tggaagcctt gcttttaaaa ggcctgcctc tcaagtcatc cgttgtaaac
    15781 tcgtcgacag ctcttttggg aatgttgcct aagggaattg cccttttgac cattacttcg
    15841 ctcttgactg cagtgattaa gttgggcttg aaaaaggtct tggtgcagga gatgtactct
    15901 gttgagacct tggcgcgcgt ggatatgctc tgtctggaca agacgggtac catcacccaa
    15961 ggaaagatgc aggtggaggc tgttcttcca ctgacggaaa cttatggtga agaggctgtt
    16021 gccagcatcc tgaccagcta tatggcccat agtgaggata aaaatccaac agctcaagcc
    16081 attcgccaga gattccaagg tcaagtagtc tatcctatgc tctctaatct tcccttctcc
    16141 agcgaccgca agtggggagc catggagtta gaaggtttgg gaatagtttt cttaggggca
    16201 cctgagatgt tgctggattc tgaggtccca gaagccagag aggccttgga gagaggatca
    16261 cgtgtcttgg tcttagctct cagtcaggag aaattagacc atcacaaacc acagaaacca
    16321 tctgatattc aggctctagc cttgctggaa atcttggatc ctattcgaga gggagcggca
    16381 gagacgctga actatctccg ttctcaggaa gtggggctca agattatctc tggtgacaat
    16441 ccagttacgg tatccagcat tgcccagaag gctggttttg cggactatca cagctatgtc
    16501 gattgttcaa aaatcacgga tgaggaattg attgctctgg cggaggagac agcgattttc
    16561 ggacgtgttt cccctcatca aaagaaactc attatccaaa cgctgaaaaa agcgggtcat
    16621 acaacagcta tgactgggga tggagttaat gatatcctgg ctcttcgtga ggcggattgt
    16681 tctatcgtaa tggcggaggg agacccggca acccgtcaga ttgccaacct ggttctcttg
    16741 aactcagact ttaatgatgt tcctgagatt ctttttgaag gtcgtcgtgt ggtcaataac
    16801 attgcccaca tcgctccgat tttcttgata aagaccatct attccttcct gttagcagtc
    16861 atctgtattg ccagtgcttt actaggtcgg tcagagtgga ttttgatttt ccccttcatt
    16921 ccgatccaga ttaccatgat tgaccagttt gtggaaggtt tcccaccatt cgttctgact
    16981 tttgagcgaa atatcaaacc tgttgagcca aatttcctca gaaaatccat gcttcgtgcc
    17041 ctaccaagtg ccctcatggt cgtgtttagc gttctttttg tgaaaatctt tggaacgagt
    17101 caaggttggt ctgagttaga aatctcaact ctcctctatt atctcttggg gtcaattggt
    17161 ttcttatccg tatttagagc ctgcatgcca ttcactctat ggcgagtcct cttgattgtc
    17221 tggtcagtag gaggcttcct agccacagct ctcttcccaa gaatccaaaa actgcttgaa
    17281 atttcaacct tgacagaaca aacgttgcct gtttatggtg tcatgatgtt ggtctttaca
    17341 gtgattttca tcctgactag tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt
    17401 ggattgcagt ttttttaggt acaagattgc cagccgaaat gtggtataat aagaggtaat
    17461 agagttttgg aaagtgagag aagatgattt caaagagatt agaattggta gcttcctttg
    17521 tgtcacaggg ggctatttta ctagatgtgg gaagtgacca tgcttatctg cctatcgagt
    17581 tggttgagag aggccaaatc aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc
    17641 agtctgcggt taaaaatgtt gaggctcacg gcctaaagga gaaaatccaa gtccgtttag
    17701 ccaatggctt ggcagctttt gaagagactg accaagtgtc tgtcattacc attgctggca
    17761 tgggtggtcg tttgattgct aggattttag aagaaggttt ggggaagtta gctaatgtag
    17821 agcgtttgat cctccagccc aataatcgtg aagacgactt gcgtatctgg ctacaggatc
    17881 atggattcca gattgtagca gaaagcatct tagaagaagc tggaaagttt tatgagattt
    17941 tggtggtgga agcaggacaa atgaagctat cagccagtga tgttcgcttt ggtcccttct
    18001 tgtccaaaga agtcagtcca gtatttgtcc aaaaatggca aaaagaagct gagaagctag
    18061 agttcgctct cggacaaatc ccagaaaaaa atctggaaga acgtcaagtt ctagtagata
    18121 agattcaagc tatcaaggag gtgctccatg ttagcaagtg aagtgattca tgcttatgaa
    18181 gccttttgcc ctcaggaatt ttctatggag ggagacagcc gtggtctgca aattggcact
    18241 ttagacaagg gtatccaaag ggtcatggtt gccctcgata ttcgtgaaga gacagtggca
    18301 gaggccattg aaaagggtgt ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct
    18361 atcaaggact tgcttgccag ccgtccgcaa aatcagattt acatcgacct gattaagcat
    18421 gacatcgcag tttatgtcag ccataccaat attgatatcg ttgaaaatgg gctcaatgac
    18481 tggttttgtc agatgctagg aatcgaggag acgacttatc tgcaggaaac aggtccagaa
    18541 cgtggaattg gacgtattgg gaatattcag cctcagacat tttgggaatt ggcccaacag
    18601 gtcaagcaag tctttgacct agatagcctt cgaatggtgc attatcaaga gaatgatttg
    18661 cagaagccta tttcaagagt agcaatttgt ggtggaagcg ggcagtcttt ctataaggat
    18721 gctttggcaa agggggcaga tgtctatatc actggtgata tctactacca tactgctcag
    18781 gatatgctgt ctgatggctt gttagcattg gatccaggtc actatatcga agtgcttttt
    18841 gtggaaaaaa tcgcagcact ccttactcaa tggaaagaga aaaaaggctg ggaactagag
    18901 attttaccta gtcaagcatc gaccaatcct ttccgtcata tctagttaga aagtgaagac
    18961 aatgaaaaaa gttgccatta ttggagcagg aattgtggga gcaacagctg cctactacct
    19021 ctcgagagaa agtgacctag aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa
    19081 ggccgcagca ggaattatca gtccttggtt ttccaaacgc cgtaataaag cctggtacaa
    19141 gatggcgcgc ttgggggctg atttttatgt ggatttatta gctgatttag agaaatcagg
    19201 acaaaaaatc gacttttacc agcgttcggg agtctttctc ttgaaaaagg atgaatccaa
    19261 gttggaagaa ctttatcaac tggccctcca gcgcagagaa gaatctccct tgatagggca
    19321 attagccatt ctggaccaag cctcagctaa tgaattattc cctggtttgc agggatttga
    19381 ccgcctgctc tatgcttctg gtggagcgag agtagatggc caactcttgg taactcgtct
    19441 gctagaagcc agtcatgtca agctggtcaa agaaaaagtg actctgacac cgttagcatc
    19501 aggctaccag attggtgaag aggagtttga gcaggttatt ttggcgacgg gagcttggtt
    19561 gggggacatg ttagaaccct tgggttatga agtagatgtt cgtcctcaaa aaggacaact
    19621 acgagattat cagctggtcc aagacatgga agcttaccct gttgtcatgc cagaagggga
    19681 gtgggatttg attccttttg caggtgggaa attgtcctta ggcgctaccc acgaaaatga
    19741 catgggattt gatttgacgg tagatgaaac cttgctccaa caaatggagg aggccacctt
    19801 gactcactat ctgattttgg ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc
    19861 ctacaccagt gatttctctc ctttctttgg gcaggtgcct gacttaactg gtgtctatgc
    19921 agccagtgga ctaggttcat caggcctcac aactggtcct attattggtt accatttagc
    19981 tcaactgatc caagacaagg agttgacctt ggaccctgaa aactacccaa ttgaaaacta
    20041 tgtcaaacga gtaaaaagcg aataatactc aatgaaaatc aaagaacaaa ctaggaaact
    20101 agccgcgggt tactcaaagc actgctttga ggttgtggat agaactgacg aagtcagctc
    20161 aaaacactgt tttgaggttg tagatagaac tgacgaagtc agtaaccata cccatggcaa
    20221 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
    20281 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
    20341 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
    20401 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
    20461 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
    20521 tgagattcct ttctatgagg cagatattcg tgacacagct accctcagag atattttcaa
    20581 gcaggaagaa ccgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
    20641 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagc
    20701 catagaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
    20761 tccgcacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
    20821 tactaagctc atgctagagg aaattttgac tgatatttac aaagcagact cagaatggaa
    20881 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
    20941 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
    21001 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
    21061 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
    21121 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
    21181 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgta tcgtagaacg
    21241 tcgcccaggt gatatcgctg cctgctactc agacccagca aaagctaaag cagaactcgg
    21301 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
    21361 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaacg
    21421 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
    21481 cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga tgggaccttg gaactcttaa
    21541 aggcctatcg ggagcaaaat ccggcagtcc attatatttc tttctctcga aattttggca
    21601 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
    21661 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
    21721 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
    21781 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtggctctgc
    21841 cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt agtcgatgcc attttaagct
    21901 tgaccgagtc caatcgtttt tcaaaggggc tcttcgcctg ggtgggtttc aaaacctact
    21961 atttggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggaaac
    22021 tctttttcta ctccattgaa gggattatta atttttcaga ttttcccttg attatagcct
    22081 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
    22141 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
    22201 ttcttggagg cattcaactc ttgaccattg ggattctcgg caagtatatc agtaagattt
    22261 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgat gataggctaa
    22321 aaaagataga atttatctga catagtcact ttttgttatt tgtaattctt ttagttcgga
    22381 gtttgggtga tttttaaaag aattagggat ttgaaatgat ttaaaaaatc tatgtagact
    22441 aaatttaaat tgtagtgact taataaataa aaaatttagg agtattatgt tatgctaagt
    22501 aaagaggatt atactgaaga aatcgggcta ataaagaaac aaaattatgt agaggctgaa
    22561 ttgtatccta tagttgctga tataattaag ccaactttaa aagatagttt atcaaaaaga
    22621 tatgtcttcg gaagacaaag aaggggtttg ggacaaattt attatggtct aagtaatttt
    22681 cctgatatag ttattttaga taagacttat gaaaacaaat ctaggaaaag tataaaaatt
    22741 gaagaatgga agaaacttcg aggatgcgtg gaagttaaga atttaaatta tagtttaatt
    22801 acagaggaaa aaatcaaatc aaccatatcg aacagttttg aacatataac tggagagatg
    22861 gaacaactaa ctggagagat gggacaactt attggagacc ttttatggta taaaaaagta
    22921 atttatacaa atggaattga atggagattt ctaagtttag atgacaagga agagatagat
    22981 aatacaattg ttgaagtagt taacaaaaga atagaaacag aagaagcggg aaattctttt
    23041 gattggtgga agaatattaa agatttatcg ttcaattata cggatatatg cctatctaaa
    23101 gattgtagac aagagtggaa tgaatttgta aaaagggtaa aggaaataga atggtagaag
    23161 tctattctca ttgagaaatt tagattttaa gttacagtaa gatttattta gagactaaaa
    23221 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
    23281 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
    23341 cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct
    23401 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
    23461 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
    23521 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
    23581 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
    23641 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
    23701 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
    23761 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
    23821 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
    23881 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
    23941 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
    24001 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
    24061 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
    24121 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
    24181 taccttgata caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta
    24241 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
    24301 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
    24361 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag
    24421 aaactggttt ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc
    24481 gatattggaa ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt
    24541 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacttt
    24601 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
    24661 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
    24721 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
    24781 attgatatcg gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    24841 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa
    24901 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    24961 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    25021 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    25081 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    25141 ccgcatcgta gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    25201 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    25261 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag
    25321 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    25381 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    25441 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    25501 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    25561 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    25621 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    25681 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    25741 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    25801 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    25861 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    25921 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    25981 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    26041 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    26101 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    26161 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    26221 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    26281 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    26341 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    26401 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    26461 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    26521 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    26581 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    26641 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    26701 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    26761 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    26821 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    26881 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    26941 tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    27001 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    27061 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    27121 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    27181 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    27241 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    27301 gcatagttga ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa
    27361 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    27421 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    27481 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    27541 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    27601 gttatgcctt tgctggcttt cagcgccagc ctcatgcgcg tagcgttcag gaagaaattg
    27661 aaaaaacctt gaccagatta aataaagggc aagccattac tgttcacggt gctggtagga
    27721 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    27781 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    27841 cgattgagct tgtggcagat gattttcatt gccgttatgc caagcatagc aagacctatg
    27901 agtttactgt ggatagagga cgtcccaaaa atccgatgcg ccgtcactat gccacccact
    27961 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    28021 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    28081 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    28141 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    28201 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    28261 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    28321 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    28381 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    28441 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    28501 ttgcgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    28561 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    28621 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    28681 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    28741 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    28801 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    28861 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    28921 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    28981 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    29041 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    29101 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    29161 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    29221 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    29281 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    29341 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    29401 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    29461 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    29521 ctcttcgaaa atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
    29581 gagcagcctg aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt
    29641 gagtaaaaag tatttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc
    29701 ccaaaaagtt agacagaaaa aatctaactt tttggggtgt ttttattatg aaattaa
//
LOCUS       DAVBED010000024        28707 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBED010000024 DAVBED010000000
VERSION     DAVBED010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.024"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..333)
                     /locus_tag="VQ547_001058"
     CDS             complement(<1..333)
                     /locus_tag="VQ547_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HET2542916.1"
                     /translation="MYEESKQLTNAQFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGGR
                     KPKLSLEDLLMGTLQYVREYRTYEEIAADFGIHESNLIRRSQWVEVTLVQSGVTISRT
                     PLSSEDTVM"
     gene            679..1632
                     /locus_tag="VQ547_001059"
     CDS             679..1632
                     /locus_tag="VQ547_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2542917.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1683..2873
                     /locus_tag="VQ547_001060"
     CDS             1683..2873
                     /locus_tag="VQ547_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2542918.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3022..3393
                     /gene="rnpA"
                     /locus_tag="VQ547_001061"
     CDS             3022..3393
                     /gene="rnpA"
                     /locus_tag="VQ547_001061"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2542919.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3368..4192
                     /locus_tag="VQ547_001062"
     CDS             3368..4192
                     /locus_tag="VQ547_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2542920.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4211..5197
                     /locus_tag="VQ547_001063"
     CDS             4211..5197
                     /locus_tag="VQ547_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2542921.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5248..5871
                     /locus_tag="VQ547_001064"
     CDS             5248..5871
                     /locus_tag="VQ547_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2542922.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6002..7459
                     /locus_tag="VQ547_001065"
     CDS             6002..7459
                     /locus_tag="VQ547_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2542923.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7482..7763
                     /locus_tag="VQ547_001066"
     CDS             7482..7763
                     /locus_tag="VQ547_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2542924.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7840..8325
                     /locus_tag="VQ547_001067"
     CDS             7840..8325
                     /locus_tag="VQ547_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2542925.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8342..9007
                     /locus_tag="VQ547_001068"
     CDS             8342..9007
                     /locus_tag="VQ547_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2542926.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            9011..9874
                     /locus_tag="VQ547_001069"
     CDS             9011..9874
                     /locus_tag="VQ547_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2542927.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9876..10580
                     /locus_tag="VQ547_001070"
     CDS             9876..10580
                     /locus_tag="VQ547_001070"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2542928.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10759..12432
                     /locus_tag="VQ547_001071"
     CDS             10759..12432
                     /locus_tag="VQ547_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2542929.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12544..13635
                     /gene="ulaG"
                     /locus_tag="VQ547_001072"
     CDS             12544..13635
                     /gene="ulaG"
                     /locus_tag="VQ547_001072"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2542930.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13749..15725
                     /gene="tkt"
                     /locus_tag="VQ547_001073"
     CDS             13749..15725
                     /gene="tkt"
                     /locus_tag="VQ547_001073"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2542931.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15842..16141
                     /gene="yajC"
                     /locus_tag="VQ547_001074"
     CDS             15842..16141
                     /gene="yajC"
                     /locus_tag="VQ547_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2542932.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16188..16616
                     /locus_tag="VQ547_001075"
     CDS             16188..16616
                     /locus_tag="VQ547_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2542933.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16618..17028
                     /locus_tag="VQ547_001076"
     CDS             16618..17028
                     /locus_tag="VQ547_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542934.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17328..19979
                     /gene="adhE"
                     /locus_tag="VQ547_001077"
                     /gene_synonym="adhC"
     CDS             17328..19979
                     /gene="adhE"
                     /locus_tag="VQ547_001077"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2542935.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20964..21272)
                     /locus_tag="VQ547_001078"
     CDS             complement(20964..21272)
                     /locus_tag="VQ547_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2542936.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21269..21577)
                     /locus_tag="VQ547_001079"
     CDS             complement(21269..21577)
                     /locus_tag="VQ547_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2542937.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21582..22877)
                     /locus_tag="VQ547_001080"
     CDS             complement(21582..22877)
                     /locus_tag="VQ547_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2542938.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22895..24304)
                     /locus_tag="VQ547_001081"
     CDS             complement(22895..24304)
                     /locus_tag="VQ547_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2542939.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24462..25190
                     /locus_tag="VQ547_001082"
     CDS             24462..25190
                     /locus_tag="VQ547_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2542940.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25650..25844
                     /locus_tag="VQ547_001083"
     CDS             25650..25844
                     /locus_tag="VQ547_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2542941.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26210..27520)
                     /locus_tag="VQ547_001084"
     CDS             complement(26210..27520)
                     /locus_tag="VQ547_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2542942.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27757..28629
                     /locus_tag="VQ547_001085"
     CDS             27757..28629
                     /locus_tag="VQ547_001085"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2542943.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8987 a         5120 c         5978 g         8622 t
ORIGIN      
        1 cattaccgtg tcctcagaac tgagaggagt tcttgaaatc gtaacaccac tttgaacaag
       61 agttacttca acccattggc tccgacggat taagttgctt tcgtggatac caaaatcagc
      121 cgcaatttct tcataagtgc ggtattctcg cacatattga agagtgccca taagaaggtc
      181 ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt
      241 taatacagct aacatctctt taaaagtcgt gcgctgaaca ccaacaagac gcttaaattg
      301 tgcattggtt agttgtttac tttcttcata aattttattg tatcatattt ttgtttcaca
      361 ggaagtctaa taaataaaaa ttctttaaaa ttttgttggg aaaatgggaa aagatataaa
      421 tggaaactta gtataacact tggaaaactc tgtaaaaata gtaagtcaat tcatgtcccg
      481 ttttttctct agggaagttg ggcggctata tttatatgac catttgtcgt aataaacatc
      541 cctaccaagg gtcaatagaa ataaattcaa cgaaactttt gctgtcagat ttagatgccc
      601 aatttgtcat ttatactctt tcatatagga ctttctataa ggatggaaaa aagaagggaa
      661 atttgataag ataggaatat ggattttgaa aaaattgaac aagcttatac ctatttacta
      721 gagaatgtcc aagtcatcca aagtgatttg gcgaccaact tttatgacgc cttggtggag
      781 caaaacagca tctatctgga tggtgaaact gagctaaacc aggtcaaaga caacaatcag
      841 gcccttaagc gtttagcact acgcaaagaa gaatggctca agacctacca gtttctcttg
      901 atgaaggctg ggcaaacaga acccttgcag gccaatcacc agtttacacc ggatgctatt
      961 gctttgcttt tggtgtttat tgtggaagag ttgtttaaag aggaggaaat tactatcctc
     1021 gaaatgggtt ctgggatggg aattctaggc gctactttct tgatctcgct tgataaaaag
     1081 gtggattact tgggaatgga agtggatgat ttgctgattg atctggcagc tagcatggca
     1141 gatgtaattg gtttgcaggc tggctttgtc caaggagatg ccgttcgtcc acaaatgctc
     1201 aaagaaagcg atgtggtcat cagtgacttg cctgttggct attatcctga tgatgccgtt
     1261 gcgtcgcgcc atcaagttgc ttctagccaa gaacatactt acgcccatca cttgctcatg
     1321 gaacaagggc ttaagtacct caagtcagac ggatacgcta tttttctagc tccgagtgat
     1381 ttgttgacca gtcctcaaag tgatttgtta aaagaatggc tgaaagaaga ggcgagtctg
     1441 gttgctatga ttagtctgcc tgaaaatctc tttgctaatg ctaaacaatc taagactatt
     1501 tttatcctac agaagaaaag tgaaatagca gtggagcctt ttgtttatcc acttgctagc
     1561 ttgcaagatg caagtgtttt aatgaaattt aaagaaaatt ttcaaaaatg gactcaaggt
     1621 actgaaatat aaaatagatt ttgttataat agttgaaaac gcttaaaaag gggtatcatg
     1681 ttatgacaaa aacaattgca atcaatgcag gaagttcaag tttgaaatgg caattatact
     1741 taatgccaga ggaaaaagtg ttagccaaag gtttgattga acgtatcggt ttgaaagatt
     1801 caatttcaac tgtaaaattt gacggccgtt ctgaacaaca aattttggat atcgaaaatc
     1861 atacacaagc tgttaaaatt ttattggatg acttgattcg tttcgatatt atcaaggctt
     1921 atgacgagat tacaggtgtt ggccaccgtg ttgtagcagg tggagaatat ttcaaagaat
     1981 caacagttgt tgagggagat gttttagaaa aagttgaaga gttgagtttg ttggctcctc
     2041 tacacaaccc ggccaatgca gcaggtgttc gtgctttcaa ggaattgttg ccagacatta
     2101 ccagtgtagt tgtttttgat acttccttcc acacaagtat gccagagaaa gcttatcgct
     2161 accctctacc aacaaaatat tacacagaaa acaaggttcg taaatacggt gctcatggta
     2221 caagtcacca gtttgtagca ggagaagctg caaaactctt gggacgtcca ttagaagact
     2281 tgaagttaat tacctgtcat attggtaacg gaggctcaat tacagctgtg aaagccggca
     2341 aatctgtaga cacttctatg gggttcactc ctcttggtgg tattatgatg ggaacgcgta
     2401 caggggatat tgatccagct atcattcctt atttaatgca atatacagag gattttaaca
     2461 caccagaaga tatcagtcgt gttcttaacc gtgaatcagg tcttttggga gtttctgcta
     2521 attctagcga tatgcgcgat atagaagcag ctgtagcaga agggaatcac gaggctagct
     2581 tggcttatga aatgtatgtt gaccgtatcc aaaaacatat cggtcagtac cttgcagtgc
     2641 taaatggaac agatgccatt gttttcacag caggtgtcgg tgaaaatgca gagaatttcc
     2701 gtcgtgatgt aatctcaggg atttcgtggt ttggttgtga tgttgatgat gaaaagaatg
     2761 tctttggcgt tacaggagac atctcaacag aggcagctaa aatccgtgtc ttggttattc
     2821 caacagatga agaattagtc attgcccgtg acgttgaacg cttgaaaaaa taagtgaaac
     2881 taaaaaaata ttcaatacaa ggagttggga aagttatttt tccagcttct ttttctgatg
     2941 aaattgtcca aaaccttgct atgattggct tttttgaaaa atatggtata atagtagtaa
     3001 tttaatagat ggagttgagt tttgaagaaa aactttcgtg taaaaagaga gaaagatttt
     3061 aaggcgattt tcaaggaggg gacaagtttt gctaatcgca aatttgtggt ctaccaatta
     3121 gaaaaccaga aaaaccattt tcgagtaggt ctatcagtta gcaaaaaact ggggaatgcc
     3181 gtcactagaa atcaaattaa gcgacggatt cggcatatta tccagaatgc aaaagggagt
     3241 ctggtagaag atgtcgactt tgttgtcatt gctcgaaaag gagtcgaaac cttgggatac
     3301 gcagagatgg agaaaaatct actccatgta ttaaaattat caaagattta ccgggaagga
     3361 aatgggagtg aaaaagaaac taaagttgac tagtttgcta ggactgtctc tgttaatcat
     3421 gacagcctgt gcgactaatg gggtaactag cgatattaca gccgaatcgg ctgatttttg
     3481 gagtaaattg gtttacttct ttgcgaaaat cattcgcttt ttatcgtttg atattagtat
     3541 cggagtgggg attattctct ttacggtctt gattcgtaca gtcctcttgc cagtctttca
     3601 ggtgcaaatg gtggcttcta ggaaaatgca ggaagctcag ccacgcatta aggcgcttcg
     3661 agaacaatat ccaggtcgag atatggaaag cagaaccaaa ctagagcagg aaatgcgtaa
     3721 agtatttaaa gaaatgggtg tcagacagtc agattctctt tggccgattt tgattcagat
     3781 gccggttatt ttggccttgt tccaagccct atcaagagtt gactttttaa agacaggtca
     3841 tttcttatgg attaaccttg gtagtgtgga tacaaccctt gttcttccga ttttagcagc
     3901 agtattcacc tttttaagta cttggttgtc caacaaagct ttgtctgagc gaaatggcgc
     3961 tacgactgcg atgatgtatg ggattccagt cttgattttt atctttgcag tttatgcgcc
     4021 aggtggagtc gccctatact ggacagtgtc taatgcttat caagtcttgc aaacctattt
     4081 cttgaataat ccattcaaga ttatcgcaga gcgcgaggcc gtagtacagg cacaaaaaga
     4141 tttggaaaat agaaaaagaa aagccaagaa aaaggctcag aaaacgaaat aaataaggag
     4201 gaatctggta atggtagtat ttacaggttc aactgttgaa gaagcaatcc agaaaggatt
     4261 gaaagaatta gatattccaa gaatgaaggc tcatatcaaa gtcatttcta gggagaaaaa
     4321 aggctttctt ggtctatttg gtaaaaaacc agcccaagtg gatattgaag cgattagtga
     4381 aacgactgtt gtcaaagcaa atcaacaggt agtaaaaggc gttccgaaaa aaatcaatga
     4441 tttgaacgag cctgtgaaga cggttagtga agaaaccgtt gaccttggtc atgtggttga
     4501 tgctattaaa aaaatagagg aagaaggtca aggtatttct gatgaagtca aggctgaaat
     4561 cttaaaacat gaaagacatg ccagcactat cttagaagaa actggtcaca ttgagatttt
     4621 aaatgaactt caaatcgagg aagcgatgag ggaagaagca ggcgctgatg accttgaaac
     4681 tgagcaagat caaactgaaa atcaagactt gaaagagatg ggcttgaagg tcgagcaaag
     4741 ttatgatatt gcccaggtgg ctacggatgt gactgcctat gttcaagcga ttgtggatga
     4801 catggatgtt gaagctacac tttcaaatga ttataaccgt cgtagcatca atctacaaat
     4861 tgacaccaac gaaccaggtc gtattatcgg ctaccatggt aaagtcttga aggccttgca
     4921 actgttggct caaaattatc tttacaaccg ctattccaaa accttctacg ttacaatcaa
     4981 tgtcaatgat tatgtcgaac accgtgcaga agtcttgcag acctatgcgc aaaaattggc
     5041 gattcgtgtt ttagaagaag gacgtagtca tcaaacagat ccaatgtcga atagtgaacg
     5101 caagattatc caccgtatta tttcacgtat ggatggcgtg accagttact ctgaaggtga
     5161 tgagccaaat cgctatgtcg ttgtagatac agaataagta aaatcagggt tgacctgatt
     5221 ttttgctagc tagaggaggt taaactaatg ttgaataaga taagagacta tttagacttt
     5281 gctggtttgc agtaccgtaa tcctgataaa gcgggagcag agcgagagaa gatgctggca
     5341 ttccgccaca aaggacaaga ggcccgaaag gcttttacag aactggccaa agcctttcaa
     5401 gcaagccatc caggatggca actccaacag actagtcagt ggatgaatca ggcccagcgt
     5461 ttgagaccac atttttgggt ttatctacag agagacgaac aagtgacaga acctatgatg
     5521 gccttacgtt tgtatgggac atctactgac tttggaattt ctttggaagt cagtttcatc
     5581 gaacgtaaga aggatgagca aacactgggc aagcaggcca aagttttaga cattccaacc
     5641 gttaaaggga tttattatct aacctactct aatggtcaaa gtcaacggtg ggaggcgaat
     5701 gaagaaaagc gtcgtacttt acgcgagaag gtgagaagtc aagaagttcg aaaagtttta
     5761 gtgaaggtag atgttcctat gacagaaaat tcgtctgaag aagaaatcgt agaaggctta
     5821 ttgaagtctt attctaaaat tcttccctat tatctagcta cgagaaaata agataatttg
     5881 taaaacatca taaatcatac agtccaagag tgaacagtcc gctgtgtaat tcttggtctt
     5941 tttgtttgcg ctttcgcatt atataataaa cttacaaaaa caattcaaaa ggagaacaat
     6001 tatggaagtc gtttcaagtg ttctaaattg gttttctagc aatattttgc agaatcccgc
     6061 atttttcgta ggtttattgg tgttgatagg atatgcactt ttgaaaaaac ctgcccatga
     6121 cgttttttca gggtttgtta aagcaacagt agggtatatg ttgcttaacg tgggtgctgg
     6181 tggtttggtt acaacctttc gtccaatctt agcagctctt aactacaaat tccaaattgg
     6241 tgcagcggtt atcgaccctt actttggact tgctgcagca aacaacaaaa ttgcagcaga
     6301 gtttccagat tttgttggaa ctgcaactac agctctattg attggttttg gaataaatat
     6361 cttgctcgta gctcttcgaa agattacgaa ggtaagaacc ctctttatta ctggtcacat
     6421 catggtacaa caagctgcaa cagtatctct tatggttcta ttcttagtac cacaattgcg
     6481 caatgcttac ggtacagcag cgattggtat catctgtgga ctttactggg cagttagttc
     6541 aaatatgact gttgaggcaa ctcaacgctt gactggtggt ggcggatttg cgattggtca
     6601 ccaacagcaa tttgcaatct ggtttgtaga taaagtagca ggacgctttg gtaagaaaga
     6661 agaaagttta gacaatctta aattacctaa gttcctctca atcttccacg atacagttgt
     6721 tgcatctgct accttgatgc tcgtattctt cggagccatt cttttaatct tgggtccaga
     6781 cattatgtct aataaagaag tcatcacttc aggaactcta ttcaatcctg ctaaacaaga
     6841 tttctttatg tacattatcc aaacagcctt taccttctca gtttacttgt tcgttttgat
     6901 gcaaggtgtc cgaatgttcg tatctgagtt gacaaacgcc ttccaaggta tttcaaacaa
     6961 attgttgcca ggttcattcc cagcggttga cgttgcagct tcttatggat ttggttctcc
     7021 aaatgctgtc ttgtcaggat ttacctttgg tttgattggt caattgatta caattgtttt
     7081 gctcatcgtc tttaaaaatc cgattcttat tattacagga tttgtaccag tgttctttga
     7141 caatgcagcc attgcggtct acgctgataa acgcggcgga tggaaagcgg ctgttatcct
     7201 ttcctttata tcaggtgtcc ttcaagttgc tctaggagct ctttgtgtgg cccttctcga
     7261 tttggcatct tatggtggct accatggaaa tatcgacttt gaattcccat ggcttggatt
     7321 tggatatatc ttcaaatacc ttggtattgt tggttatgta cttgtgtgtc tcttcttgct
     7381 tgttattcct caacttcaat ttgccaaagc aaaagataaa gagaaatatt acaacggtga
     7441 agttcaagaa gaagcttagt atctagaaaa ggagaaataa aatggttaaa gtattagcag
     7501 cgtgcggaaa tggaatgggt tcatcaatgg ttatcaagat gaaggttgaa aatgctctcc
     7561 gtaagcttaa tcaaacagat tttacagtca attcatgcag tgtcggtgaa gctaaaggtt
     7621 tagcagtagg atatgacatt gtaatcgctt ctcttcattt gattcaagaa ttggaagggc
     7681 gaactaatgg gaagttaatt gggcttgata acttgatgga tgataaagaa atcaccgaaa
     7741 aactcagtca agcactacag taaaaggttg gagggggctg gacagaaact gagagttatc
     7801 gtttctgtcc agccccctct ttaaataaag gaggcagata tgaatttaaa acaagcttta
     7861 attgacaatg actcgatccg actaggttta gaggctaaca attggaaaga agcagtcaag
     7921 gtagcagtag atcccttgat tgaaagtggg gcaattttgc cagagtatta cgatgctatc
     7981 attgaatcga ctgaagagta tgggccttac tatatcttga tgccaggtat ggctatgccc
     8041 cacgctagac ctgaagctgg tgtgcaaagt gatgcctttt cattgattac cttacaaaat
     8101 cctgttgtat tttcagatgg gaaagaggta tctgttttgt tggcactagc agcaacaagt
     8161 tcaaaaattc acacaagtgt agccattcca caaattattg ccctgtttga attagaagat
     8221 tctattgcac gtttacaggc ttgccagact aaagaagatg tcttggctat gattgaagaa
     8281 tctaaggata gcccttatct cgaaggattg gatttggaaa gttagaaaga ggaataaaga
     8341 aatgacaaaa agaataccta atttacaagt tgcattagac cattcagact tgcaaggagc
     8401 gattaaagca gctgtttctg ttggtcagga agtagatatt atcgaagctg gaactgtttg
     8461 cttgcttcaa gttggaagtg aactggctga agtcttgcgt agccttttcc cagataagat
     8521 tattgtggca gacacaaaat gtgctgatgc tggtggaaca gttgctaaaa ataatgcggt
     8581 tcgtggagca gactggatga cttgtatctg ttgtgcaacc atccctacta tggaagcagc
     8641 tctaaaggct atcaagactg aacgaggaga acgaggcgaa atccagatcg agctttatgg
     8701 cgattggact tttgaacaag ctcagctttg gctagatgca ggtatctcac aagctattta
     8761 tcaccaatct cgtgatgctc ttcttgctgg tgaaacttgg ggtgaaaaag accttaataa
     8821 ggttaaaaaa ctcattgaca tgggcttccg tgtatctgta acaggtggtc tagatgtaga
     8881 tactctcaaa ctctttgaag gtgttgatgt ctttaccttt atcgcaggtc gtggaattac
     8941 agaggctgcg gatccagcag gagcagcgcg tgccttcaag gatgaaatca aacgaatttg
     9001 ggggtaaatc atggtacgtc caattggaat ttatgaaaag gcaaccccaa cacactttac
     9061 ttggctagaa cgtttaaatt ttgccaagga gttaggcttt gattttgtcg agatgtctat
     9121 tgacgaacgt gacgagcgtt tagcaagact tgactggagt aaggaagaac gcttggaagt
     9181 tgtcaaagaa atctatgaaa ctggtgttcg tattccttct atctgttttt caggccatcg
     9241 tcgctaccca ttgggttcaa aagatccagt tctagaggaa aaatctctag aactcatgaa
     9301 aaaatgtatc gaattagctc aagacttggg agttcgtacg attcaattag ctggttacga
     9361 tgtttactat gaggaaaagt caccccagac acgccaacgt tttatcaaaa atttgagaaa
     9421 agcctgtgac tgggctgaag aagctcaggt ggtacttgct attgaaatta tggatgatcc
     9481 tttcatcaat agcatcgaaa aatatttggc tatagaaaaa gagattgact ctcccttcct
     9541 ctttgtatat ccagatattg gtaatgtgtc tgcatggcat aatgatatct atagtgagtt
     9601 ttatcttggt catcatgcca tcgcagctct ccatctcaag gatacttatg cagtgacaga
     9661 aagttcaagg ggccagttcc gagatgtacc ttttgggcaa ggttgtgtca aatgggaaga
     9721 agctttcgat attttaaagg aaaccaatta taatggacct ttcctaatcg aaatgtggtc
     9781 tgaaaattgt gaaacagtag aagaaacacg cgcagccatt caagaggcgc aagcttttct
     9841 ctatccactc attaagaaag caggtttgat gtaagatgaa tcaagtaatc aatgctatgc
     9901 gtaaacgagt ctgtgatgcc aatcaatcat tgccaaaaca tggacttgtc aaatttacct
     9961 gggggaatgt atctgaagtc aatcgcgaac tcggtgtcat tgttatcaaa ccatcaggcg
    10021 tggattatga cgaattgaca cctgaaaaca tggtagtgac tgatctagat ggtaagatcc
    10081 tagaagggga tttaagacca tcttccgacc tcccaactca tgtgcaatta tataaggctt
    10141 ggtcagaaat tggtagtgtg gttcacaccc attcgacaga agctgttgct tgggctcagg
    10201 caggtcgtga tattcctttc tacggaacaa cccatgcaga ttatttctac ggttcaatcc
    10261 cttgcgcccg tagtttgacc aaggacgaag tagaagtggc ctatgaaaaa gatactggcc
    10321 tggttatcgt agaagagttt gaacatcgcg gacttaaccc ggttgaagta ccaggaattg
    10381 ttgtacgcaa tcacggtcca ttcacctggg gcaaaaatcc agagaatgct gtttatcact
    10441 ctgtcgtact agaggaagta tcaaagatga atcgctttac agaacaaatc aatccaagag
    10501 ttggacctgc tccccagtac atactagaaa aacactacca acgtaaacat ggaccaaatg
    10561 cttattatgg tcaaaagtaa gaacgatgaa ggaggagaaa aagataaatt tagctcctct
    10621 ttttacattt gatttttatt gagagtaaag ttggagttga agtaatttta aaagattttt
    10681 tagaaatagc gcttgatata tatatggtaa aataaaaaga attgctgtga tatcaataga
    10741 tttgggggat tttttaatat ggtactggat aaggcaagtt gtgatttgct tcaatatttg
    10801 atggatcaag aaacgtccaa aacgattatg gcgatttcga aagatttgaa agagtcaaga
    10861 aggaaaattt attatcacat tgacaaaatc aatgctgctc tgggtgacga ggcgcttcac
    10921 atcattagta ttccacgaat tggtattcac ttaacggaag agcagagaga tgcttgttgt
    10981 aaactattat cggaagtaga ttcgtacgat tatatcatga gtgcgcatga acgtatgatg
    11041 ataatgttac tatggatagg tatttctaaa gaacgtatta cgattgaaaa attgatagag
    11101 ttaacagagg tatctaggaa tactgttctc aatgatttga atagtattcg ttatcaacta
    11161 actttggaac aatatcaggt gatcttgcaa gtgagcaagt cacagggata ccaccttcat
    11221 gcccaccctc ttaataaaat tcagtatctt caatcgcttc tatatcatat ttttatggaa
    11281 gaaaatgcca cttttgtatc tattttagaa gataagatga aagagaggtt agatgatgag
    11341 tgtttgcttt ctgttgaaat gaaccaattt tttaaggaac aggttccttt agttgaacaa
    11401 gatttaggga agaaaataaa ccatcatgaa ataactttta tgttgcaggt tctaccttat
    11461 ttgctgttaa gctgtcataa tgttgaacag tatcaagaaa gacatcagga tatagagaaa
    11521 gaattttctt tgataagaaa aagaatagag tatcaggtgt ctaagaaatt aggagaacgg
    11581 ttgtttcaaa agtttgaaat ttctttgtca ggacttgaag tttctcttgt agctgttctc
    11641 ctcctctcct atcgtaaaga tttggatatt catgcagaaa gtgatgattt tcggcaatta
    11701 aaacttgctt tagaagaatt tatctggtat tttgaatcac aaatccgaat ggagattgag
    11761 aacaaggatg atttgttacg aaatttgatg atccactgta aagccttgtt atttagaaag
    11821 acttacggta ttttttctaa aaatcctcta acaaaacaaa ttcgatccaa gtatggagaa
    11881 ttatttttag tcactagaaa atctgcggaa attttagaag gagcatggtt tattcggcta
    11941 acagacgatg atattgccta tttgacgatt catattggag gatttttaaa atatacacca
    12001 tcatctcaaa aaaatatgaa aaaagtttat ctcgtttgtg atgaaggtgt tgcggtttcg
    12061 agacttttgc tgaaacaatg caaactttat tttccaaatg agcaaattga cactgtattt
    12121 acaacagaac aatttaagag tgtggaagat attgcacaag ttgatgtagt gattactact
    12181 aatgatgatt tggatagcag atttccgatt ttaagggtta atcctatcct tgaagcagaa
    12241 gatattttga aaatgctaga ctatcttaaa cacaatatat ttcgtaataa gagcaaaagt
    12301 ttcagtgaaa atctttctag tcttatttcg tcttatattg tagacagcaa gttggctagt
    12361 aagttccaag aagaggttca aacacttata aatcaagaaa tagtagttca agcttttttg
    12421 gaagatattt gaaggacagt ccaatgatga acacaaacct gtgtttttct tggtcttttt
    12481 tagtgttttg aagggtggta tactaatctc aaagataaca attatatcca aaggaggcaa
    12541 catatgccaa acgtcaaaga aattacaaga gagtcatgga ttttagccac tttcccagag
    12601 tggggaacat ggttgaacga agaaatcgaa gaagaagtcg tacctgaagg caactttgcc
    12661 atgtggtggc taggcaactg tggtacttgg attaagacac cagctggtgc taacgttgtc
    12721 atggaccttt ggtcaaaccg tggaaaatca accaaaaaag tgaaagatat ggttcgtggg
    12781 caccaaatgg caaatatggc aggtgttcgt aagctgcaac caaacttgcg tgttcagcca
    12841 atggttatcg atccatttgc tatcaacgaa ctagactatt acttagtttc acacttccac
    12901 agtgatcata tcgacccata cacagctgca gcaattctca ataatcctaa gttagagcat
    12961 gttaagttta tcggtcctta ccactgtgga cgaatctggg aaggatgggg tgttccaaaa
    13021 gaacgtatca tcgttgttaa accaggtgac actatcgaat taaaagatat gaagattcat
    13081 gcagtagaat catttgaccg tacttgcttg gtaactctcc cagtgaacgg tgctgatgag
    13141 acaggcggtg aacttgctgg cttggctgtt acagatgaag aaatggctca aaaggctgtt
    13201 aactatatct ttgaaacacc aggtggaacc atctatcatg gtgcagattc tcacttctca
    13261 aactattttg caaaacatgg taaagacttt aaaattgatg ttgctttgaa taactatggt
    13321 gaaaatccgg taggtatcca agacaaaatg acatctatcg accttcttcg tatggcagaa
    13381 aatctgcgta ccaaagtcat tatcccagtt cactatgata tctggtctaa cttcatggct
    13441 tctactaatg agattctaga actttggaaa atgcgaaaag atcgcttgca atacgatttc
    13501 catccattta tctgggaagt tggcggtaag tacacttatc ctcaagatca acacttagta
    13561 gaataccatc atccacgtgg ttttgatgat tgttttgaac aagactctaa cattcaattt
    13621 aaagctttgc tataatataa aaatattctt tggaggttat ccgtatgttg catgatacgg
    13681 ataattttca tataatagta aaatagaatg tgtgattcaa taatcacctc aaatagaaag
    13741 gaaattctat gtcaaatcta tctgttaatg caattcgttt tctaggtatt gacgccatta
    13801 ataaagccaa ctcaggtcat ccaggtgtgg ttatgggagc ggctccgatg gcttacagcc
    13861 tctttacaaa acaacttcat atcaatccag ctcaaccaaa ctggattaac cgcgaccgct
    13921 ttattctttc agcaggtcat ggttcaatgc tcctttatgc tcttcttcac ctttctggtt
    13981 ttgaagatgt cagcatggat gagattaaga gtttccgtca atggggttca aaaacaccag
    14041 gtcacccaga atttggtcat acggcaggga ttgatgctac gacaggtcct ctagggcaag
    14101 ggatttcaac tgctactggt tttgcccaag cagaacgttt cttggcagcc aaatataacc
    14161 gtgaaggtta caatatcttt gaccactata cttacgttat ctgtggagac ggagacttga
    14221 tggaaggtgt ctcaagcgag gcagcttcat acgcaggctt gcaaaaactt gataagttgg
    14281 ttgttcttta tgattcaaat gatatcaact tggatggtga gacaaaggat tcctttacag
    14341 aaagtgttcg tgaccgttac aatgcctacg gttggcatac tgccttggtt gaaaatggaa
    14401 cagacttgga agccatccat gctgctatcg aaacagcaaa agcttcaggc aagccatctt
    14461 tgattgaagt gaagacggtt attggatacg gttctccaaa caaacaagga actaatgctg
    14521 tacacggcgc ccctcttgga gcagatgaaa ctgcatcaac tcgtcaagcc ctcggttggg
    14581 actacgaacc atttgaaatt ccagaacaag tatatgctga tttcaaagaa catgttgcag
    14641 accgtggcgc atcagcttat caagcttgga ctaaattagt tacagattat aaagaagctc
    14701 atccagaact ggctgcagaa gtagaagcca tcatcgacgg acgtgatcca gtcgaagtga
    14761 ctccagcaga cttcccagct ttagaaaatg gtttttctca agcaactcgt aattcaagtc
    14821 aagatgcctt gaatgttgtg gcagctaaat taccaacctt tctaggtgga tcagctgacc
    14881 ttgctcactc aaacatgact tatatcaaga cggatggact tcaagacgat gccaatcgct
    14941 tgaatcgtaa cattcagttt ggtgttcgtg aatttgcaat gggaacaatc ttgaacggga
    15001 tggcccttca tggtggactt cgtgtatacg gtggaacttt cttcgtcttc tctgactatg
    15061 tgaaggcagc tgtccgcttg tcagccttac aaggacttcc tgtgacttat gtctttaccc
    15121 atgattcaat cgcagttggg gaagatggtc cgactcatga accagttgag catttagcag
    15181 gtcttcgtgc tatgccaaat ctaaatgttt tccgtccagc agatgcgcgt gaaacgcaag
    15241 cagcttggta ccttgcagtg acaagtgaga aaacaccaac tgcccttgtc ttgacacgtc
    15301 aaaatttgac tgttgaagat ggaacagact tcgacaaggt tgctaaaggt gcttatgttg
    15361 tatatgaaaa tgcagccgac tttgatacca tcttgattgc gacaggttca gaggttaatc
    15421 ttgctgtctc agctgctaaa gaattggcta gtcaaggcga aaaaatccgc gtagtcagca
    15481 tgccatctac agatgtcttt gataaacaag atgcagctta caaggaagaa attcttccaa
    15541 atgcagtccg ccgtcgtgtt gcagtcgaaa tgggtgcaag tcaaaactgg tacaaatatg
    15601 ttggtctcga tggtgccgtt ctaggtattg ataccttcgg agcctctgcc ccagcaccaa
    15661 aagtattggc agaatatggc tttactgtag aaaatcttgt aaaagttgtt cgaaacttga
    15721 aataatccta aaaatcaggg cgtaagctct ggtttttctt accagaaaag taaggtacaa
    15781 tcttgtaaaa gtagctgaaa tttgatatag tagtcctatg taaaagacaa aggagaaaac
    15841 aatgaatcca aatattactt ttttaatcat gcttgtaggt atgatggcct tgatgttctt
    15901 tatgcaacgt tctcaaaaga aacaagctca aaagcgtatg gaaagcttaa ataaactaca
    15961 aaaaggctat gaagtgatta caatcggtgg actttatgga acagtcgatg aagtagatac
    16021 ggagaaggga acaatagttc ttgacgtaga gggagtttac ttgacttttg aactagctgc
    16081 tatcaagaca gtattaccgc tgaaagaaac agcttcacta gaaggcgcaa ttgaaaaata
    16141 agacgggatc acgaactccc gtttttctat aaaagaaagg aaatgggatg aaaaaattag
    16201 tctttgtctg tctgggaaat atttgccgta gccctatggc cgagtttgtt atgaaatcaa
    16261 tgacagataa ctacgaaatc caaagtcgag caacttcctc ttgggaacat ggcaatccga
    16321 ttcataaggg gactcaggga atttttcaag agtatgagat tccttatgac aagaacaaga
    16381 catcgcttca gattagtaag gaagattttg aagcctttga ttatattatc ggaatggacg
    16441 cttcaaatat ttctgactta cgtcagatgt gtccagtaga ctgtcaagat aagatttact
    16501 cattttcatc tgaaagtgtt ccagaccctt ggtatacagg agattttgaa gaaacctatc
    16561 gacgtgttca agagggctgt caagcttggt tagaacgttt agaaaaggag agttaaggtg
    16621 gaaaatctta cgaattttta cgaaaagtat cgtgtctatc tgactcgtcc acgtttagag
    16681 cttttggcag tagttaccat tgttttctgt gctgtactcg tcttttttct aaatattcca
    16741 ggaaaaggtg tcttaaaact cgataatgga acgattgttt atgatggcag tcttgtccgc
    16801 ggtaaaatga atggccaagg taccattacc ttccaaaatg gagaccaata tacaggtggc
    16861 ttcaacaatg gagccttcaa cggaaaaggt acctttcaat ctaaagaagg ctggacctac
    16921 gaaggtgatt ttgtaaatgg tcaggctgaa ggaaaaggga aactaacaac agaacaagaa
    16981 gtcgtttatg aaggaacttt taaacaaggc gtttttcaac aaaaataaag cctccttatc
    17041 aaaggaggta ttattagaat cgcaaggtaa gcgcttacct gcaaatccct ttctttccaa
    17101 atccctcttc caagcaagtt tgtgaaataa aaaatatttg aaataaattt cacaaacttc
    17161 aaagataaaa cctgataaga aaagaaaatg agaaaagttt cacaagagtt taaaaattct
    17221 ttgtgaaatg tttatgaaac tgtttacaaa gttgaaataa tgcgttataa taaacttgtg
    17281 aaaaaattaa caaaggatat cgttccttga aagctatgga ggaaaatatg gctgataaaa
    17341 aaactgtgac accagaggaa aagaaactcg ttgctgaaaa acacgtagat gagttggttc
    17401 aaaaagctct agttgccctt gaagaaatgc gtaaattgga tcaagaacaa gttgactaca
    17461 tcgttgccaa agcatcagta gcagctttgg atgcccacgg agaattggct ttacatgcct
    17521 ttgaagaaac aggacgtggt gtatttgaag ataaagcaac taagaacttg tttgcttgtg
    17581 aacacgtggt aaacaacatg cgtcacacta aaacagttgg cgttatcgaa gaagatgatg
    17641 taacaggatt gaccctgatt gctgaaccag ttggtgttgt ttgtggtatc actccaacaa
    17701 caaacccaac atcaacagcg atcttcaaat cattgatttc attgaagaca cgtaatccaa
    17761 tcgtctttgc cttccatcca tcagctcaag aatcatcagc tcatgcagct cgtatcgtcc
    17821 gcgatgcagc tatcgcagct ggtgctcctg aaaactgtgt acagtggatc actgaaccat
    17881 ctatggaagc aactagtgcc cttatgaacc acgaaggtat tgcaacaatc cttgcaacag
    17941 gtggtaatgc catggttaaa gccgcatact catgtggtaa accagctctt ggggtaggtg
    18001 ccggaaacgt tccagcttat gttgaaaaat cagcaaacat tcgtcaagca gcacacgata
    18061 tcgtcatgtc taaatcattt gataacggta tggtctgtgc atctgaacaa gcagttatca
    18121 ttgataaaga aatttacgat gaatttgtag cagagttcaa atcttaccac acttactttg
    18181 taaacaaaaa agaaaaagct cttcttgaag agttctgctt cggcgtcaaa gcaaacagca
    18241 aaaactgtgc tggtgcaaaa ttgaacgctg acatcgttgg taaaccagca acttggattg
    18301 cagaacaagc aggatttaca gttccagaag gaacaaacat tcttgctgca gaatgtaaag
    18361 aagttggcga aaatgagcca ttgactcgtg aaaaattgtc accagttatt gcagttttga
    18421 aatctgaaag ccgtgaagat ggtattacta aggctcgtca aatggttgaa tttaacggtc
    18481 ttggacactc agcagctatc cacacagctg acgaagaatt gactaaagaa tttggtaaag
    18541 ctgttaaagc tattcgtgtt atctgtaact caccttctac ttttggtggt atcggggacg
    18601 tttacaatgc cttcttgcca tcattgacac ttggatgtgg ttcttacgga cgcaactcag
    18661 ttggggataa cgttagtgcc attaacctct tgaatatcaa aaaagtcgga agacggagaa
    18721 ataacatgca atggatgaaa cttccttcaa aaacatactt tgaacgtgat tcaattcaat
    18781 accttcaaaa atgtcgtgac gttgaacgtg tcatgatcgt tactgaccat gccatggtag
    18841 agcttggttt ccttgatcgt atcatcgaac aactggacct tcgtcgcaat aaggttgttt
    18901 accaaatctt tgcggatgta gaaccggatc cagatatcac aactgtaaac cgtggtactg
    18961 agattatgcg tgccttcaaa ccagatacca tcatcgcact cggtggtggg tctccaatgg
    19021 atgctgccaa agtaatgtgg ctcttctacg agcaaccaga agtggacttc cgtgaccttg
    19081 tccaaaaatt catggatatc cgtaaacgtg ccttcaagtt cccattgctt ggtaagaaga
    19141 ctaaattcat cgcgattcca actacatctg gtacaggatc tgaagtaaca ccatttgccg
    19201 ttatctctga taaagcaaac aaccgtaaat acccaatcgc tgactactca ttgacaccaa
    19261 ctgtggcaat cgtagatcct gctttggtat tgacagttcc aggatttgtt gctgctgata
    19321 ctggtatgga cgtattgact cacgcgacag aagcatacgt atcacaaatg gctagtgact
    19381 acactgatgg tttagcactt caagccatta aattggtctt tgaaaatctc gaaagctcag
    19441 ttaagaatgc agacttccac tcacgtgaga aaatgcataa cgcttcaaca atcgctggta
    19501 tggcctttgc caatgccttc ctaggtattt ctcactcaat ggcccataag attggtgcgc
    19561 aattccacac aatccacggt cgtacaaatg ctatcttgct tccatacgtt atccgttaca
    19621 acggtacacg tccagctaag acagcaacat ggcctaagta caactactac cgtgcagatg
    19681 aaaaatacca agatatcgca cgcatgcttg gacttccagc ttctactcca gaagaagggg
    19741 ttgaatctta cgcaaaagct gtctacgaac tcggtgaacg tattgggatc caaatgaatt
    19801 ttagagacca aggaattgac gaaaaagaat ggaaagaaca ttctcgtgaa ttagccttcc
    19861 tggcttatga agaccaatgt tcaccagcta acccacgtct tccaatggta gaccatatgc
    19921 aagaaatcat cgaagatgca tactatggct acaaagaaag accaggacgc cgtaaataat
    19981 tgtttatcag tctagaagca agacaaaaac tcaatttgag ggaaagatcc agtaattttt
    20041 ctatgataaa aggcatccta tcaaggtttt tgaacacctg ataggatgcc tttttatgat
    20101 attgaggcct ttttgccctt tttgaaaaac tagaatagaa acaaaatata taatagattg
    20161 aaactggaat agtacacttc tgcttctaaa acattgttag aattcgattt gactgtcctg
    20221 atcgatttgt cctattccta tttcatttta ctatataaaa aatatagtat agtagactga
    20281 atctaaaata gtacgaaaca attgctaaaa catttataga aattaatttt actttcctga
    20341 tagagttgtt cacatcttat ttcaattcac tatagtttaa tttaagagta gtatttacta
    20401 aggcccaatt aaaatcaaag agcaaactag aaaacgagtg ccattcagct caaaacactg
    20461 atttgagatt gcagataaga ctagcccctc attaacaggt ttacgataaa acgatgacaa
    20521 ggtgtgttgc tttttgattt ctaaagagta taatgataga tctctataaa ataagtgcga
    20581 aggaaatgag cttttatagt cctttcgttt taaaatacta tctcagatgt tcttatatcg
    20641 acaagaagtt tttgagtcat tccctcatca tacatattaa ataaatagtg gctcattcaa
    20701 ttttttacta gaataataag ctagtatagt aaactgaaat aagatataaa caaataaatt
    20761 ggagcttaac atctatttcc agcaattttt tagaaactgc agtggactat tctaaattca
    20821 acacattata aaaactagag taaaagaaaa ggattggatc ttgtgtaatg caggatctaa
    20881 tcctttcaat cattttgtcc aacttttgga ggttcctaca atgtagccgt cattaataaa
    20941 gacagatggg aacgacagtg ttcctattta ttttgataga gatcgatgaa ttctttagat
    21001 agcaactgaa taatctctgt tgaagccatt tggtcttctg catgcataaa tagcaaggag
    21061 aatcctattt tttctccagt agcttctttt tgtatgagat tagagtgaat cttgtgcgct
    21121 tctactaagg agtcttccgc ttcttcaact ttaattttcg cttcttttaa atttcctgcc
    21181 ttagctagtt ggatggcttc aataaaggat gatttggctg ctccactatt ggcaatgagc
    21241 tgaaaacaga tatattccat ttcttctgtc atcttatttc tcctatccat gcaagtgctt
    21301 gttccagaac ttttgctcca ttcatcattc cgtaatcccg catatcaatg gtatctacag
    21361 ggatatttcc tgcaatttct ttcacagcaa gtaactcata acgaatttgt ggcccaatta
    21421 gaatgacatc tgcttcatgg atattctttt tcgcttctgt cattgatttt gcttggatag
    21481 aaatttcaat cccacgttca gtcgcacttt gttgcatttt tttaacaagc atacttgtcg
    21541 acattcccgc attacatact aataaaattt gtttcataat cttaaccttc catttcttgc
    21601 tcaacaactt tgtcattaac tttgataaat ggaatgtata gaagaactcc aagtgcaaag
    21661 atgatgaatt gaactagaac tgctctcacg tcccctgctg ttgctaacca tgcatttaag
    21721 aatactggtg tagtccaagg aacttgtata aatgcaggac tcatgaatcc tgtaactgtt
    21781 gctaagtagc tgattaaaat accaaggact ggaactgtga taaatggaat agctaatgaa
    21841 atgttataaa cgattgggta accgaataat actggttcat tgatattgaa gataccaggt
    21901 ccaaaagata atttagccac gtttttagaa acagcattgc gactcactaa gaatgttgct
    21961 attaataaac ataatgtaga tccactacca cccattaaag cgaatgtttg tatttgtgat
    22021 aagttgatga tgtgtggaat ggcttgtcca ttatttgctg cagtgatgtt ttcagtaatg
    22081 ttaattaata gtaatggttc taggatggca ctgtaaataa ctgcttggtg aataccaaat
    22141 agccataaca tatttcctaa agagtaaata ataatgaccc cgattaagct tgtaccaata
    22201 tgacgaattg gttcttgaat aaagattgta atgattgaga ttaagttcat tccagttata
    22261 ttgaataata atgctgaaac aatcccaaat aaggagatga cagtcatgac tggaagtaat
    22321 acgctaaatg atctactaac agctggtgga atattttcac caaggttcat ttgtaaagct
    22381 ttaacgtttg ataattcaat gaataattct gttgcaataa tcgctacgat aaccccggcg
    22441 aacattgcgc ctgtacctgt gttgttgaat gaaagaacac ctgaaatgtt tacagcatct
    22501 tttgctccgt caggaactac agaaactgta tttggcatca tcacaattaa agaaactaat
    22561 gatagcattg atgctgctga cgggttttcg aaatctctgt ttttagctaa gaaataacca
    22621 accattacag caataatcat acctgaaata cttaaagtac cgtttgcaat tgttattccc
    22681 caatattgga attttgttaa tgtatcccct tggaaaatcc acttaaatac cgtgttgttc
    22741 aaaagaacga ttaaacctgc caaaatatat aatggcatta ctgttacgaa tgcatctctt
    22801 agggttttta aatgaatttg gttccctagt ttaccagcaa aggtggcaaa ttgatctata
    22861 aattttgagt ttttcatctg aatatctcct ctctttactc ctcaatttct acttcaaaac
    22921 cgttattgtc acttactttg cgataccatc ttcctgagct cttgatggtt ctcttttgcg
    22981 tttctaaatc aacggagata aatccgtaac gattcttata tgcattattc caagaccagc
    23041 aatcaaatgc ggtccaagcg tggtatccaa aacagagact tccctcttca atggctttat
    23101 gtagccatct taaatgttct tcataaaatt caatacgata cacgtcatcg ataactccat
    23161 tttcatcgat aaaccgtgct tcgttttcaa cacccattcc gttctcactg ataaaccatg
    23221 ggatattacc atattcttcc ttcacaatca tagcaatatc ataaatggct ttcggaaaaa
    23281 tttcccaacc acgatatgga ttcatgcgac gctccggcca ttcatactct ttgaagtatt
    23341 ggtctggcat ccagggcgtc tgatattcct caggatttgc ttgtgcttga acacgttttg
    23401 gatggtagta gtttactcca agaaaatcaa ccgtatttga tttcatcagt tgaagctctt
    23461 tttcggtatg actccataac acgccatctc tctctagctg ttttaccaat ctttctggga
    23521 aagttccttt aacagctgga ttcaagaaga ctttgttaaa gaagtcttct gtaaatcgac
    23581 ttgcttctaa gtcttctgga gaattacttc ttggataagc aggtgtcaag tttaaaataa
    23641 tcccaatctt tccatcaagt cctaatgagc gatatagttg aatcactttt gcactagcaa
    23701 ggtttagatt atagatgact tgtacggcct cttttccctt tccttttaga tttggataat
    23761 ggaaagcata taagtatcct gcttctggaa tgaccattgg ctcattgaaa gttgtccagt
    23821 aatgaacctt atctccaaag catgtgaaag cagtcttggc aaacttcacg aataactcca
    23881 ctacatgttt gctttcccaa ccaccgtatt tttgaagaag ttccactggt aaatcaaaat
    23941 gatgtaaatt catcacaaga tccatctggt tctttttagc ttcttcaatg atggcattgt
    24001 agaaagcaat accttttgga tcaggctcac ctgtctctaa attcttgatg agtcgactcc
    24061 attggatgga agtgcggaaa gaattaactc caatttcctt catcaagtgg aaatcttcgg
    24121 tgtaagtatg aaaaaagtta ctggctacaa gaggtccgac attatcgaaa aaatcttctg
    24181 gatgcgtttt gaaccagtag tccatcacat tttcatgtac ttttccatat tgaccttctg
    24241 tctgaggtcc gctagaagca gctccccacc aaaacagatt aggaaatact aacttttttt
    24301 tcatgctcaa cctcctttct attatgctat acataaagta tagcataatt ttaaaatttg
    24361 tctagacatt tttaaaaatt gttgatacat atattgtgtt tgcctcattt cttgaacttt
    24421 gttatactac tattagaata ttatagagag aaccagatta aatgagtaca aaatatttat
    24481 ttatttacaa tgagattcgt gaaaagattc tctgtaataa atataccatg aacgaacaat
    24541 tgcctgatga aatgacatta gctaaacagt ttgcctgtag tcgaatgacg atcaaaaaag
    24601 ctttagactt gttagtttct gagggcttaa tttttagaaa acgtgggcag ggaacctttg
    24661 ttctctctcg tggcagctca aaaagaaaat taatcgttcc agaaagagat atccggggac
    24721 tgacaaaaat atctgaagat gctcattcta caattgactc gaggattatt cacttcaaat
    24781 tagaatttgc aaatgaattt ttagcagaaa aactacaggt cgctttgcag agtccagttt
    24841 ataatattta ccgcctgcgt attattgacg gtaaacctta tgttctggaa caaacttata
    24901 tgagtaccga tgttattcca ggtattactg aagatatttt acaaaaatcg atttacaatt
    24961 acattgaagg aaagttagga ttgcatattg ccagtgctac aaaaatcttg cgagcttctt
    25021 ctagttcaga aaatgagcaa cattacttgc agctccttcc aacagaaccg gtatttgaag
    25081 tagaacaagt ggcttatttg gataacggaa ctccgtttga gtactcgatt agtcgtcatc
    25141 gctatgattt atttgaattt aattcttttg cattacgaca ttcctcctag gagaaaatgt
    25201 gaaaatgaag ccaatctttt acaggctcta gtttaagaaa aatttaaaac agggcaagaa
    25261 ggtcccatct atgcttaaat ggtttctctt ttctaaataa gatggcttta aaagagtgat
    25321 cgttttatcc atcatgttga aaaatatctt cgtatagctt atagagtagg tactgaaatt
    25381 gttcacctga tctacttctt atagttattt agttttaaat agtgtttcaa acattcttac
    25441 actgacgaga agtttttgag tcttttcttg taacacatat agtatactga ggttagaata
    25501 gtagactgtg acttctaaca aattgctaga aatgaatttc aatctcccaa tttatttgct
    25561 tatatattat tttaatatat taaataaatt ctggatcata atcatttaaa aaaattttat
    25621 ttttttattt ttcattacga ataatataga tgaaggggaa agagtatgaa aacagaactg
    25681 tttcttttgc tattagttca aaaggagaaa aaatgaaagt agaaaatatt tcgtataggg
    25741 tggatcatcg tatattgttt gataatattt cttttgatac ttcgagttca gacgtgacat
    25801 taattactgg taaaaatggt acaggaaagt caactttact atagtggatt gaaactagaa
    25861 tagtacacat ctacttctaa aatattgtta gaaatcgatt tgactatcct gatctatttg
    25921 tcctgttctt atttcatttc actatatctc aaattgagta tgacgaagtg cgctcccatg
    25981 tcctgggaac gcactttctt catatttttc atattcttga atccatcgat aaagactatt
    26041 gggatgaatt tttaaagttg aactaatcat ttttacagga tgaggtttac agcagagagt
    26101 ttgaaggctt tatcaaaggt ttttcttggc ataatgactt ttcctcgttt ccacttaatt
    26161 ttgtgtctac tttattatac caagtccacc cttaagttag ataataaatc taacttaagg
    26221 aagctagaag gatgagaatc caggtggtca agagtcccaa acttaagctg attgggacac
    26281 ccagaataat ttgctttttg aaggcaaggc cacgttcctc tatattggga agtgagagtt
    26341 gaatgagaga accagctgat gaaaagggtg agatattagt agatagagcg ccaataacgg
    26401 tggctgttgt gagtaagtga atatcaatct ggggattttg agcactgatg atagcaatga
    26461 tgggaaagag ggctggagct acaacggata gggtggaact aaagagtgac atcaccccgg
    26521 ctatcacaca aaagaacaga ggtaaccaga aatgaggaat ggatgttgtc atgaggtgcc
    26581 ctatcagtgt gactaaacct gacttgaccg ctagagacat tagtaagctc atgccgcaga
    26641 gcatgataat tgtagcccag ggaactttag ccaaaatggc ttcttgcttc cctaatttga
    26701 gccttaaggc gaggcagacc atgagtattg agacaaagcc aatatcaaat gtttttcgat
    26761 aagtagctat ccaggcgatg tttgggaaaa tgagatgcaa caagggaaaa agccaaacca
    26821 aaaccatgct gctgatcatg agcaaggtgg tttgtctttg aaccttgctg aggagtggtg
    26881 gttggtcaat agtcaaggat gagtttgttc ttcccttact atagtgactg taacaggata
    26941 ataaaagcaa gacaatgagt gggtagataa tgctgacgat aaagatatga ttgccaagtg
    27001 aaaaagcttg ctcttcccat cccatttgct taaacaggcc ttgaaagaca atgcctgagc
    27061 tactggttat caaattagcc cctcctgaag ctccccaatt gacggcttga gctccaatca
    27121 aagggtgttt gtccgctttt tgacagagag taatcgctag aggacagcaa acggccatag
    27181 tagtgaaaaa tccagcacct aaagcagaca aaagggttgc catcaggtat aaaatcatgt
    27241 agagggcgtt agggtaggtg cgtgtgcggt agagaatgtg ttgagccaaa acatcaagag
    27301 taccgttagt tattgcaaag ttataaaaga gagagacgct aaaaatggta aaaaagagtg
    27361 aggttggcca aaaatgaaga agttctttgg ggcttaatcc catgagagtg gttgcgatga
    27421 ggtaagaaaa agcaatagcc agcaggccaa tattgatttt ggtgcggtaa ccaattccaa
    27481 tggctagagc aatggcgcta atcattatta aatgaatcat tgaattgtcc tttcagttag
    27541 aatatggaaa taggttggca attttggcgc tcaaaagacc acctgtttcc tattggtact
    27601 tgactattat acacaaaaaa aatacaattg tcttgacaat tgtattgaca cttgttagaa
    27661 ttaaaaatga ggtattcagg cttgtgattt cctatggaag ttaatagtga ttgcctctaa
    27721 tgcttacaag tgatattaaa aatagaggac ctagtgatgt caatcatttc aactgattta
    27781 accccttttc aaatagatga tacattgaaa gcagccttgc gagaagatgt tcattccgaa
    27841 gattacagta ccaatgccat ttttgatcat catggccaag ccaaggtgtc gctttttgcc
    27901 aaggaagctg gtgttttagc ggggctaacc gtttttcaaa gggtttttac cctatttgat
    27961 gccgaggtga ccttccagaa tcctcatcaa tttaaggatg gggatcgttt gactagtggc
    28021 gatttggttt tagaaatcat aggctcggtg agaagtctct taacatgtga acgcgttgcc
    28081 ttgaattttt tacaacattt atcagggatt gcttcgatga cagctgctta tgtagaagcc
    28141 ttaggcgatg attgcattaa ggtatttgat actcgaaaaa ctactcctaa tttacgtctt
    28201 tttgagaaat atgcagtgag agttggcggt ggctataatc atcgctttaa tttatcagat
    28261 gctatcctgc taaaagacaa tcacattgcg gcagtaggta gtgttcaaaa ggcaattgct
    28321 caagcgcgtg cctatgcccc ttttgtgaaa atggtcgagg tggaagtgga aagccttgct
    28381 gctgccgaag aagctgcggc ggcgggtgct gatattatca tgttggataa tatgtcattg
    28441 gaacagattg aacaggccat taccctaatt gcaggacgtt ctcggattga atgttctgga
    28501 aatattgata tgaccactat tagccgtttt cgtggtttag cgattgatta cgtctccagt
    28561 ggtagtttaa cccatagtgc taagagtctt gatttttcca tgaaggggtt aacctacctt
    28621 gatgtctaag ttgtaaaata aactaacttt ttaaaggatg tctttcctct agaacgagtt
    28681 ttatgtcaga tagtttaaac gcctctt
//
LOCUS       DAVBED010000025        28638 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBED010000025 DAVBED010000000
VERSION     DAVBED010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.025"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(503..2230)
                     /gene="ezrA"
                     /locus_tag="VQ547_001086"
     CDS             complement(503..2230)
                     /gene="ezrA"
                     /locus_tag="VQ547_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2542944.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2312..4258)
                     /gene="gyrB"
                     /locus_tag="VQ547_001087"
     CDS             complement(2312..4258)
                     /gene="gyrB"
                     /locus_tag="VQ547_001087"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2542945.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4273..4836)
                     /locus_tag="VQ547_001088"
     CDS             complement(4273..4836)
                     /locus_tag="VQ547_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2542946.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4921..5475)
                     /locus_tag="VQ547_001089"
     CDS             complement(4921..5475)
                     /locus_tag="VQ547_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2542947.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5486..6709)
                     /locus_tag="VQ547_001090"
     CDS             complement(5486..6709)
                     /locus_tag="VQ547_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2542948.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6746..9196)
                     /locus_tag="VQ547_001091"
     CDS             complement(6746..9196)
                     /locus_tag="VQ547_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2542949.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9395..10324)
                     /locus_tag="VQ547_001092"
     CDS             complement(9395..10324)
                     /locus_tag="VQ547_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2542950.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10464..10751
                     /locus_tag="VQ547_001093"
     CDS             10464..10751
                     /locus_tag="VQ547_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2542951.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10785..12119)
                     /gene="ciaH"
                     /locus_tag="VQ547_001094"
     CDS             complement(10785..12119)
                     /gene="ciaH"
                     /locus_tag="VQ547_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2542952.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12109..12783)
                     /gene="ciaR"
                     /locus_tag="VQ547_001095"
     CDS             complement(12109..12783)
                     /gene="ciaR"
                     /locus_tag="VQ547_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2542953.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12892..15438)
                     /locus_tag="VQ547_001096"
     CDS             complement(12892..15438)
                     /locus_tag="VQ547_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2542954.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15562..16002)
                     /locus_tag="VQ547_001097"
     CDS             complement(15562..16002)
                     /locus_tag="VQ547_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2542955.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15977..16846)
                     /locus_tag="VQ547_001098"
     CDS             complement(15977..16846)
                     /locus_tag="VQ547_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2542956.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16888..17616)
                     /locus_tag="VQ547_001099"
     CDS             complement(16888..17616)
                     /locus_tag="VQ547_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2542957.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17624..18103)
                     /locus_tag="VQ547_001100"
     CDS             complement(17624..18103)
                     /locus_tag="VQ547_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2542958.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18114..18812)
                     /locus_tag="VQ547_001101"
     CDS             complement(18114..18812)
                     /locus_tag="VQ547_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2542959.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18805..19071)
                     /locus_tag="VQ547_001102"
     CDS             complement(18805..19071)
                     /locus_tag="VQ547_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2542960.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19137..20063)
                     /locus_tag="VQ547_001103"
     CDS             complement(19137..20063)
                     /locus_tag="VQ547_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2542961.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20138..20953)
                     /locus_tag="VQ547_001104"
     CDS             complement(20138..20953)
                     /locus_tag="VQ547_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542962.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20957..21277)
                     /locus_tag="VQ547_001105"
     CDS             complement(20957..21277)
                     /locus_tag="VQ547_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2542963.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21574..21654)
                     /locus_tag="VQ547_001106"
                     /pseudo
     CDS             complement(21574..21654)
                     /locus_tag="VQ547_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21698..23695)
                     /gene="metG"
                     /locus_tag="VQ547_001107"
     CDS             complement(21698..23695)
                     /gene="metG"
                     /locus_tag="VQ547_001107"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2542964.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23819..25078)
                     /locus_tag="VQ547_001108"
     CDS             complement(23819..25078)
                     /locus_tag="VQ547_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2542965.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25080..25781)
                     /locus_tag="VQ547_001109"
     CDS             complement(25080..25781)
                     /locus_tag="VQ547_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542966.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25765..26964)
                     /locus_tag="VQ547_001110"
     CDS             complement(25765..26964)
                     /locus_tag="VQ547_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2542967.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27250..28596
                     /gene="gor"
                     /locus_tag="VQ547_001111"
     CDS             27250..28596
                     /gene="gor"
                     /locus_tag="VQ547_001111"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2542968.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8570 a         6299 c         5113 g         8656 t
ORIGIN      
        1 agtataaata gcgagaaata tctatcctat cttctagaat gtcttccaaa cgagaaaact
       61 ctcgtaaaca aagaggtttt agaggcctat ttaccgtgga ctaaagttgt acaagaaaag
      121 tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt
      181 caatagactt cgttattgga cggttaccaa gttacttcaa agtacagatt tgaagctgca
      241 gataagactg acgaaatcac tttaatacta aatgaaaatc aaaaagcaaa ctaagaagct
      301 agcctcaggc tgtacttgag tacggtaagg cgacgctgac gtgatttgaa gagattttcg
      361 aagagtataa aacactgttt tgaagtggtg gataaatcgg ctgggtaaaa actcaatctc
      421 aggagaaaat gaagtaaatc tccccacaac tatagaaaaa gatttgattc tgctcctcac
      481 acaataaaat ctttttcttt tattaaaaac gaatcgtttc acgtgttttc tcatatgagg
      541 taacaaagcg attggttaca ccaggctctg ccacttccaa tgcttgagaa atcttgtcaa
      601 atgaagcgtg ataatcaaat tctttttcaa aaatatctaa agcttcgtta aatgcttctt
      661 gaatgcgttc atcaaatgag cgatagcggt tagaatattg caagagttgc tctgtcaaag
      721 ttgcatattg tacaatatta taagtttccg tttctaaagc ttccatatca ttcgttgcaa
      781 tttcaagaac tcgggtaaca gattcaatgt taatcatttt ttgttctaac tcaaccatta
      841 aatcctcggt attattgctt gccgtaaaga ataacttcaa gaaagtttgt ggaatacctg
      901 gcagattgcg tttttccatg tatcgcttga tagtatggag acgattgaca taaacattgg
      961 ccttttgacg tgcattaata tcatctttct caatttgtgt caggcgctca ctaactgaaa
     1021 tttgctcatc ttcaatatct tttagttgag tttgtaaatc ctcaagattt tcttcaagaa
     1081 ctgaataagc ttgggttggt tcttcttgat ttgaagttac ctcaacaata gctgcctcaa
     1141 aactctctaa ttctgtctga atacgacgaa catggcttgc agctgtctca ggaagtaaat
     1201 aggtcttgtt caaacgtgca atatcttctc ccaataaagt attattctct ttcatatgtt
     1261 gaaggtaagt tggaagagtt gcaagtagat tttccactac tttctgagca gcaatttctc
     1321 gagtaaaaat atcatacaag gcattgattt cctcttgtgc ctgtccattc tcatattcgg
     1381 cattatccaa ttccaactga cgaatattct cttggttttt cttgaatgct tcataaagca
     1441 agtggaaacg cgcttcaata tccgtttcaa caaaatgata attagcatca attagtttac
     1501 gataaccggc ttccaaatcc tgtaattgat ctggcaattc tgtagaaagc gtcgtaacca
     1561 aggctggaac acgatccaca atatgactta aggccaaaat gtgattttct gtattatcca
     1621 aaatcactgc ggcttccaca gggtcacccg atgaattcaa ggttacaaat tgtgaaaatt
     1681 cagattggat attttctaat tgtttttcaa tttcatccaa ggcttgacca tactgttctg
     1741 aattttcagc aactctatgc tgaagttcct caaataaatc caaagcatga agaacacgac
     1801 cactattttt agattcttgc ttctctaagt ctgccaaagc attgcgaatt gccgcaatat
     1861 cttcttcaat caaagtaatt tgactctcaa tttggtcaat ttgatgactg gccttgagaa
     1921 aacgaaatga atggttataa ccttctgctt caaagagatt attttcaata tcggcaaaag
     1981 agttgagaga taaatcgacc catttttgat tccattcacg gaaagccact tgactttgtc
     2041 caatcaagtg catatttttt acagcttcta cttcatcatt tactggaaga ttgtatagtt
     2101 cttcttttct ttcttctagc gcctctaatc tcccctcgtt tcgcttacgt agaaagattg
     2161 ccactacata agccagaact aaaatgactg caattgcaac cattaaataa attagttgtc
     2221 cattagacat atcaaactcc ttttttactt gaaacaatcg taacgattat atcatatttt
     2281 ttagaccaag ggaactactt ctccctattt tttagacatc aagtgtacta tagacagcat
     2341 tttcttcgat aaactcacga cgaggctcta ctcgatcccc catcaacata tcaaagattt
     2401 tatctgcttc tgcagcatca tctacagaaa ctctagccat caagcgatgt tcgggatcca
     2461 tggttgtttc ccacagctga tgatcgtcca tttcacctag ccccttataa cgctgaatag
     2521 tcggtttggt acgaccttca ctataacggg ctaaagcttc ttggagtttg atttcttgat
     2581 ctgcacccgg ctggatatat tctttaatct cgcttccaac cttgacacca tagattggtg
     2641 gttgggcaat ataaacataa ccagcttcta ggattggttt catataacga taaatcaagg
     2701 ttaaaagaag ggtacgaata tgggctccat cgacatcggc atcggtcatc aaaacgagtt
     2761 tttggtaacg ggctttcgaa acatcaaatt ctgcgccaaa tcctgttccc atggctgtga
     2821 aaagactacg aatttcttcg ttagctagaa tcttatccat acttgctttt tcaacgttca
     2881 aaatcttacc gcgaattgga aggatagcct gaaactcacg gttacgacca gatttggctg
     2941 atccaccagc tgagtctcct tcgacgatga agagttctgt ttcagcaggg ttattagaag
     3001 aacagtctgc tagtttccct ggaaggttgg aaatttccaa accagatttt ttacgtgtga
     3061 cttcacgcgc acgcttggca gccacacgag ccttggcagc taaaatccct ttttccacga
     3121 tacgtttggc aatctgtgga ttttccatga ggaaatcgga gaaggcttca ctgaagaggc
     3181 gattggtaat cttgaccact tcgctatttc ccaatttggt cttggtttgt ccttcaaact
     3241 gtggatttgg gtgtttaact gagataactg cagttaatcc ttcgcgaaca tcttcccctg
     3301 ttaaattatc ttcattgtct ttcagtaact tattcttacg agcataatca ttgataacac
     3361 gagtcagtgc cgtacggaaa ccttgttcat gcgttccacc ttcatgggta tgaatattat
     3421 tggcgaaact catgacattt tcatggtaac ctgttgtgta ctgcatggct acctcaactg
     3481 tgatatcatc catctcaccg tctgtataga ttggtgtatc aaagattaca tccttgttct
     3541 cgttgatata ttcaacgtaa ctagcaatcc caccttcata atgataatgc ttggtttgtt
     3601 ccaaaccttg gcgcttatca gtgatagaaa tttgaagacc gcgatttaga aaggccaact
     3661 cttgaatccg tttatttaat ttatcaaaat caaaggttgt tgtttcagta aagatttttg
     3721 ggtccggtat gaagtgaacc gttgttccag ttctatctgt atccccaacc acctcaaggt
     3781 ctgcaacaac atgaccacga cggtattctt ggtaatgaat cttaccgttt ttatggacat
     3841 gaacgtctaa ttgagtggaa agggcattaa ctactgacga ccccaccccg tgaagaccac
     3901 ctgaaacctt gtatccacca ccgccgaact ttcctccagc atgaaggact gtaaagacgg
     3961 tctcaacagc aggacggcct gttttttcct gaatatcgac tgggatacca cgcccatcat
     4021 ccacaacagt aatcgaatca tctggctcaa taaaaacttg aatatggctg gcaaatcctg
     4081 ccaaggcctc gtcaattgag ttatcaacaa tttcccagac tagatggtga agaccttctt
     4141 ttgaggttga tccaatgtac atccctggac gcatacgaac agcctctaag ccctctaaaa
     4201 cttgaatttg actggcatca taatcctgtg cctgcagatt tttgatttct tctgtcatct
     4261 tattcctttt tcttatatgt ctaatacttg tcttaaattc acgatactgg taaacaagtg
     4321 ggtatcaagt cctgcagctt gacctgcttc gatatcaatc ggccgatcac caatgacaag
     4381 accagagcta atctgatact tttctcttaa ataaagcatg gattcgggat ttggctttct
     4441 cttaaagcct gagctagaag tcaccacttc tgtaaaataa gctgctatag aggttttttc
     4501 taaaatttcc aaaacctgat catttcgatg agagaccaaa aaatgacggc caccttgatt
     4561 taaaatgtct tccaataggt cagaaactcc ttcaaataaa atcgggtgtt caagctctct
     4621 ggcttcattt tccttgtact tttctaaaaa attctctaaa ttgggagcga atgtctcaat
     4681 cgcaaaagga gtagaaacct ttaaagcttg atagacactg tcatggtctt gtgtgatacc
     4741 atacagtgcc aatgtttcaa caaatgcagc tgttgaagtt tcataattat ccagtaaagt
     4801 tccacctaaa tcccagatgt aatcgtgata tttcataccc ttcattatag cattttttta
     4861 tgaaaaaagc gatgatttcc ctgagttttc cacataaaaa acgagagaat aactcccgtt
     4921 ttactgattt ttaccaaaga catctcgata gagcattcct gttcgtaaac tctctgcgtc
     4981 ccctcctagt tgctccacca actcgtaggc aaaggcaagg gctgttgaag gaccccgact
     5041 ggttgtcaac tgaccatcta ccactactgt ttccttgacg tagtgaccat caaggatttg
     5101 ctcttgaacg ccgtcataac aagtgtatcg cttatttttc aatatctctg cttgattgag
     5161 ggcaattggt gccgcacaaa tggctgctag tttcttccct tcttgctcga agctttgcaa
     5221 ttcttgaatc aaggtctgat tatcacgtaa atgtgcagaa ccaggcatac ctccaggaag
     5281 aacaatcata tcatagtctg ataaatctcc atcaaagaca tgatctgctc ttacttggat
     5341 tgcatgcgaa cccgttactt gctcttcaaa accaaccata tcacatgtga tattggctcg
     5401 acgcaagaca tctacaactg tcaaggcttc aatttcttca aagccctgag ctaacataac
     5461 tgctactttt accatgattt tctccttatt taatttgttt taatacaacc tttttccgtt
     5521 tgaatgggac ttttccgctc ttttcttcag ctagattagt ctggtaactc atcgataaaa
     5581 gcaaaccaac accaatcaga ttactgataa tagctgatcc cccttgcgaa atgaaaggca
     5641 agggaatccc cgtcaaagga agtagtccag tcacagcacc gatattctca aagatgtgga
     5701 agagcaacat cataatcaaa cctgtggaaa tataagtgta gaactggtta tttgatttaa
     5761 gagtaatctt caacatacgg taaatcaaca tgagatagag ggcaataacc aggacagagc
     5821 caataaagcc aaaatcttct gcaataaccg taaaaatcat atctgactct cgaactggga
     5881 taagcagatt cgaagcatta aatccctgac caaataagcc accactccca atggcaatct
     5941 gcccttgagc ctgctggtaa gtcgttgttt gggcaaactc aaagggattg agccaagcca
     6001 aaatccgatt gatttggtag gtcggcattc caatctggtg aagaaaagct cgtccgtcct
     6061 tgctaataaa gatagctaag aaaccagcaa ctcctgttac agcagtcaca aatactggga
     6121 taataatttt ccaagaaacc cctgataata aaacgattcc tgagaaaatg gctacaaaaa
     6181 ccaaagccgt ccccaagtca ctttgaagtg ctaaaagaac taggactgga atggtaaaga
     6241 gaatcatcca gaaaattaac aaaaagtcca gcgaaaccgt gcgtctccat tccttatgtt
     6301 tctttgtaaa ttggacaatg acacgagcca acatgaggat ataggatatc ttcataaatt
     6361 ctgacggttg aaatagggta attccattta ttgataccca gtttttggca cccgttgatg
     6421 caactaagct tggattataa aatacaatcg gcaagatcat aagtcccaag cctaaaatat
     6481 atagaaaggg ggtcaccttc caaagaaatt ctgtattaaa gagcatgacc acaaaaccaa
     6541 tcacaagccc caaggcaatc caggcgacct gctgccctaa aatgggcaga atattattgg
     6601 gataatcatg actaacggct atatagatag ccaccacacc gatgaccagt agaaaaaata
     6661 ctggcaagag caaactataa tcgactctag agtcgagaga acgtttcata tatactaacc
     6721 ttatactttc atacaatact atttatcaaa gttcattaaa aaatctatca atagcctcgt
     6781 caacttcgga tcgagagatg gttttaacag tcgcttcttc tgctagagat gctactattt
     6841 gtttgccgta tcgttttccg atgattctcc tatccaaaat aagagttaag gaacgttggt
     6901 attcacgtct catacttctt cccaaagcct gttttaaacg aataatggcc attggcaatt
     6961 gataatcata aaaggcattt ttcccttctt gattcagttc ttgattaatc tttttcgtca
     7021 agggttcttg aggattttgg aaaggaagcc tcggtacaac ttgaatcaca aaaggatggc
     7081 ttgaaaaatc aactccctcc cagaaacttg ctgcaccaag caagatttgt tgttcacctt
     7141 tttcaaagcg tttctttagc tgatgaacat ccccattttt atactgggcc aagtggctaa
     7201 ctgtaagtaa atccgatact gctagaagca tgtctttagc ggtaaagaga accaaaatcg
     7261 gttgctggaa agcttgaatt tccactagta aagcagctac ctctctggca tagacttcta
     7321 aggaggtttc tgttaccaga gggaaatctt tgaccataac cacttcttgt tcctgttttc
     7381 cccgagattc aatcttgaca aatttggctt caggatagcc taaaaggtct gccaaagaaa
     7441 ccctctgact aatctcaaga gtagccgata ctcccatggc ttggcaactc tcaggaagta
     7501 aagaggacag aagagtacgg cctgattttg tagaagaaat ctgaattttc ttttgactcg
     7561 tttcagttac ttcaagccag taatcacctt cagctgtaaa atagcgaacc agctcatcaa
     7621 agccttctac ttctaattct gaaaaatact gatggagatt gtccagagaa tctaagatat
     7681 ttttcctaga tttaccagac tgaaattgtt ctatcaagta gagacactca aagcgaatac
     7741 tttctagtat ccgttgttga accctgtttt cttctcctac taaagcctta tcaattaaat
     7801 cgataataga ttgtatatcg taggtctctt gaagcagatt ttctagagct aacaaaatct
     7861 tttggacttc atcaataatc agtaaacggt cactgacaaa ttcaggatta tcttcaagtc
     7921 tggtcacgag ataggcatga ttagtcacta aaagcttgca agtctctgcc ctttcttgac
     7981 tacgtttcca aaaatcttcc gtcacaaata agctctggga tgataaattc ccatcatgac
     8041 gaaggtctgc tagaaaatgt tggtaacgat agagttgccc gatttcatcc aaatctcctg
     8101 tctctgtctc agtaagccag accaagactt gcattttaaa gcgtctaaat aagcgatttt
     8161 catcattttc ctgcaaggaa tgataaaagg catccaactt cagataattt tgtggtccct
     8221 ttaagctatg aatatctgta tggaacactt ccttgaggcg tttaccttct tcttccatga
     8281 tttgattttg aagaatcttt gtcggaacac taagaacaat ttgtcgctct ttggattgag
     8341 ataaagcggg taagagatag ccataggttt tcccaatccc tgtcggcgct tgaatcagag
     8401 agacaggttc atctttcaat agcaagccaa cctctttagc aaaactttct tgttcctccc
     8461 tcacttcaag gttcaacaga gaaatatttt tagaaaagtc ttgagatagt tttcgtggct
     8521 ccagagaagc tgccgttttc ttaaaataca gaccttgaac ttggaccaag tctggagaac
     8581 tcaggataga ttggttgcga taagtttcct caataaccag gtaggactca tataggagag
     8641 cgtcagccat ttccagcaag cgttccaaga gacctttagg aagctgagtc atcttttccc
     8701 gtaaaaaaag aagtaattct gctgtagctt gggcatctga aagggctgtg tgtgcgtgtt
     8761 taagaggaat tcctaattct cgacacaaaa tcggcaagct atatttttcc agttcaggga
     8821 aaaagacctg ggccaattcg accgtatcaa cacgagggtt tcttagctca tagccttcaa
     8881 aaaataaatt ttccgccaag agattagcat caaactgaac attatgggct acaaaaatcc
     8941 catcctccac caagtcaaat atttttctgg caacttgcga aaaatcaggt gcttgcgcca
     9001 gacgttggtc tgtcaatcct gtcagttctt tgatatgagc atccaagggt tcatgtggat
     9061 tgacatccgt cgtatagtga tcgacgattt ctccgtcctc aatcacgaca attcccactt
     9121 ggataatttt agccttacta cctgtgctag ttgcctctaa atccaccaca acatagcgat
     9181 taccaatcgt tttcattata aaaaattata ccaaaaaaag ggccatttgg cacctgcaaa
     9241 cataggataa ttttcaaact caagaacact acttttctta aaaatcccat cgaatagagc
     9301 attctagcct gctgattttt taaaatagtg aagaaatacg aaaaattgag agaagaaatg
     9361 ttttcatctt ccttctctca acgaatcatg tattttattt aaccatgtca ggatcgtagt
     9421 cataaaatcc tgtatcaagg aaacggtttt tagggtgaag tttacgaact tcttcatcca
     9481 gcaagaaggc ttggtcatgg ctaaagttgc cctcttgaat caagctacgc gcttggataa
     9541 agagttttgc aatctcaaca aagttctgac caggagtgta gagcccttct agtttccagc
     9601 gagtaaagcc atgctccacc aattctgtta atttgatcat caaatcaagg tcattgttgg
     9661 caaagatatg ggtcccatga ttatcttcaa aaatggaata gtggctctct ggatcacttg
     9721 gctcagccaa gaagaggtca cgtttatgcg tcttttcatc atcgatatgt gtaaagttat
     9781 agtagttttg caagagtgga cgtttagaat gatggatgac gctagcaccg taaaccaaaa
     9841 cttcagcagg aatttccaaa atctctggca ttttgaaaag ttcagctgat ggaatttcac
     9901 gcgccaaaac agcctcagat gcgccagcct tttgtcccca gaagttaatc tgacgactgc
     9961 tagttaccat ggttgaagca tcgtagatgg tcttaaatga ataaccatcg cggttaacta
    10021 cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct tccaagaagt
    10081 ctaagaaagg cttgatacgg tccatcatat cttggtgcat gagagcattg accgcaacga
    10141 gcaattcctt accagcatca tgaaccaact tagcgatttc acgtaattgg tcataactaa
    10201 aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac atagatacgg tctacgccag
    10261 cttcgagtag ttgttcaact tgttcaatac tttcagcagt tgctgtaatg acaatctttt
    10321 ccataagaaa aattatacca catttctcca aaatcatcca tgctttgaaa atgaaaaggg
    10381 actttattct ttttgtaacc tttctgtaat aattctctgc cgaaaaaatg ataaaatagg
    10441 tatgtactgt taaggagaga attatgcccg taagaaaatt acaatcctat gaggtagact
    10501 atcaagaaga attaaaccag cagcttcctc attaccaagc ttatacacct gaagcgcaat
    10561 ctgatgccaa tctcaaggaa atcctatttt ttattaatat cgctgttttt tgtatctgta
    10621 ttgctatctt tagttttatc tttttagcat taaaattatc aactgctctt gcctttgccg
    10681 cagcaatcgg attcagctta cttgttttaa aagttcaacg gtctattatc aaacgaaaac
    10741 gtagaagata aatccaaaat atcgccccag ttggagcgat atttttattt tttcttttta
    10801 gatggtgtct gaatggcaat cttcacttca aagattgttc ccttgggttt attatctttg
    10861 acagtaacag ttccttttag agcatctaca atttgcttgg ctagggataa tcctaaacca
    10921 aaaccacctt tttgccgagt tctagccttg tctactcgat aaaaacggtc aaaaattttc
    10981 tttttatctt ctgtcgaaat accgattcca ttatcagaaa caagtaaata aagattgcga
    11041 tcggtcgccg agataagaaa atcaatttca ccatcctcct cagtatactt gacggcatta
    11101 tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat ctgtgacaat tgttcgatgg
    11161 atacgatttt caaaacggaa gacacgatta ttttccgaag caatcatctc gtagtttgtg
    11221 aaagttgtat taaaaaagct agttggaact tctgcaagct ccggcttaat cccatcatct
    11281 ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac ttcttccaaa
    11341 ctcgatgcaa tgctttcgct cacatccata atggtagctt ctggcttacg aaaaagggtc
    11401 tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact catgactggc attttccaca
    11461 aaagactgtt gcttctgcat actctcaagc aggggcctaa cactgaccct agctagatag
    11521 agactggcaa gtaaagacaa aatccagaaa ctagccatca cgaccacaat caattgctca
    11581 tgcttttgac tagcctgttc caactgactg gtattaatca agacagcagc atacttgata
    11641 ttggttgaaa ccgaactaat attggtctcc atcaaaatca cacgatagat ttcttcctgc
    11701 ccatagctat taaaaacctg aatctggtag atatgtccta gttctttctt ttctaactta
    11761 atcttatcca agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc tttatcaaag
    11821 agaatgactt ccgtattgga actgacatta ggttttattt ctactttact agcgtccgcc
    11881 ctagcatttt ctaaatcttt aatctcttct gttgccctat ttatagccag ctgaataact
    11941 gcttgaggat tttcactcag tccatgaagc ttatcgtcca ccgaagtata aagactcgaa
    12001 tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa gacaccgaag
    12061 ttgcggataa aataactaaa gtcatccgca taccatgttt ttttaagttt actgaacatc
    12121 ttttaaaaga tacccaacac tacgcaaagt ttgcaaattc tctgcaaaag tggttccctt
    12181 taatttctta cggacttttg aaacatagac ttcgacaacc gaaatcgttg tatcactatc
    12241 aaatccccat agacggtcaa aaatctgcgt cttaggcaaa atcacatttt gattttgaag
    12301 gaaataaact agtaaatcga actctttccc cagcaattcg acaggagtat cttcaacttt
    12361 aacggtattg gttgataaat taaccacgat attcccataa gtcaaggtgt tttcattaaa
    12421 cttccctgaa cgtttgagaa gggcctgaat ccgcatttta agttcttcta ggtagaaagg
    12481 tttggtcaga taatcatccg ctcccagttc aaatccatgt cccttgtcat ccaaactttc
    12541 cttggcagtc ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt cttttaagac
    12601 ttggaaacca tttttttctg gcaacatcaa atccagcaaa atcaagtcat agacaccact
    12661 ctcagcttcg tagagacctt cttctccatc aaatacctgc ataacatccg caaaatcgtc
    12721 taaaaagtca aatactgaat ttgacagacc taggtcatcc tcaaccaata agatttttat
    12781 catgagaaac tcctccttat taaaactatt ataccaaatt tgccttaaaa aaaactcaac
    12841 tctctgcatt ttacatgaga tagctgagtt ttctttttat tttaggctta tttatgcatt
    12901 tccgtattga agaacaactg cttcgactgc agctttttca cggctaatca agtcaacacg
    12961 cgctgcaatt tccttgattc ccataccgat gttacggcta agagcaaggt cagaaagttg
    13021 cggctcaaag aactccttgt attccgccaa gcgttgctga gtcttaaata catgagcagg
    13081 aaggataaca aagctatcaa agctcatatc tcctccaagg gctgccttaa tccaagccca
    13141 gttttcacgc gcccaagacc aagctgtttt ctgagttgct tgatgagcta ggaattggta
    13201 ataccaagca gacaagtcct gtggtttgac cacaaatttg tccttccaag aagtaatcaa
    13261 gttttggata ttatccgcat ctgtactgta tgcaagagct gctgccaact ggcgtttaaa
    13321 gacagcatct gttgcgtgag tataagtatc aagataaagt gctaacaagt ctttagtctc
    13381 atgatgtttc atctcattaa tcagaacttg tgaacgaata gctgctggga gtcctgcaag
    13441 attctccttg tgtgttgcga agatttggct agcgacttga ctagcttctg catcatttga
    13501 gcgaatcatc atcgaaacag ccagctgacg aaccaattca tcctcatctg attctccgtc
    13561 tttagcttca aaaccaagac ggtcatagtt atgacgagcc aatttagcaa ccagtccttt
    13621 gaaggctgtt tcagcatccg ttccttcatc aataaagcgc tcaagggctg aaatcacttg
    13681 agaaacagct gaaaccacca gataagactc ttccttagca agtttatcaa gaactggaag
    13741 caagtctgca taagcaatgt gccctgcctc agccaacaaa cgacgttctt gaacaatttg
    13801 cagtttgctt gtgttatcaa gtgtctctag ctcagcaaga acagcttcta acaagtctcc
    13861 ttgatagtcg gtaatatagt gggcagtatt ttcagtgttg agacgaagag ctccttcatt
    13921 ttcagcaaga agagctgcgt agccagggat ttcgatactt tcagtttcga gtgtatcagg
    13981 caagcctttc cagttgctat tgaggggcac cacccagaga cggttcttgt cttcgttctc
    14041 accgatgaag aattgttttt gtgaaatctt caagacatca ttttcaactt taacagtaag
    14101 aactgggtaa ccaggctgtt ccaaccaaga atccatgaag gctgcgacat cacgtcctga
    14161 cgcttgacca agggcatccc aaaggtcact accaatggtg ttgctgtatt ggtgtttttc
    14221 aaagtaggcg tgcaaacctt tagcaaaatc agcatctcct agccaacggc gaagcatgtg
    14281 catgagacgg cttcctttgg catagacgat agcgccgtca aagagtgtat tgatttcatc
    14341 tggatgttta acttcgacgt ggacagactg aacgccatca gtagcgtcac gttcaagagc
    14401 aagaggtact ccacctgttt ggaaatcttc aaagatattc cagcttggtt cgatggtatc
    14461 cacacagacg tattccatca tattagcgaa actttcattg agccaaaggt catcccacca
    14521 tttcatagtc acgaggttcc caaaccattg gtgagccaat tcatgggcca caacaagggc
    14581 aacttgttga cggctagcaa atgtagagtt ctcatcgaca accaagtaaa cttcacggta
    14641 ggtcacaaga ccccagtttt ccatagcacc agctgagaag tcaggaaggg cgatgtggag
    14701 agattgagga attgggtact taactccata gtaatcttcg taaaactcga tagagcgaac
    14761 agcgatatcc agtgagaaat caagatttga aagtggatgt gctttggttg agtagacacc
    14821 taccagggta ccatttttag ttttagcggt caccccttgc aaatcaccag caacaaaggc
    14881 caacaagtaa gaagacatgc gaggtgttgt ctcaaacttc cagatacctg tttccttacg
    14941 gttttcaaca tcgatttctg gcatgtttga caaggccaat tcaccttctg cttggtcaaa
    15001 gcgaagagag aggtcaaaag ttgctttggc ttcaggctca tccacacatg ggaaagcttc
    15061 gcgcgcaaaa tggctctcga actgagtaga caagacctcc ttcttgactc catcaactgt
    15121 ataataagaa gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac
    15181 caattcaact tgaccagcct cagccaattc gatatgaagg gcttcattgt catggtcaac
    15241 tgtaaatgga cgagcttgac ctgcaacttc tacagaggtg atttccaagt ctttttggtg
    15301 gagggagatg cggtcactct gtgcttgacc agtgatggtc actttcccag aaaaagtctt
    15361 ggtctcacga ctcaaatcta aaaataaatc ataatgttca ggaacaaatt gcttaataaa
    15421 atgttcaact gcttgcatag ttttctccta ttctaagttt aagagctact gctcttcttc
    15481 aaacaaactt attatatcat attttgcttg agaaaaaagg attggacagc gatttccaaa
    15541 actttcttcc ttctaaatag tctacagtgg gtagaccttg cgaaattctt ctaaaacaac
    15601 cttgctttca ggtgtaaaag tcagccctac ttcacccaaa cagtctgtga aaaagtcctc
    15661 atgaacctgg cgccaatagg caagtgattt gtctccctca ccttccttaa aggcatgttg
    15721 cgcagaaact tgattgaaga gttcaacaga aacctttgta atttcgacaa tgcagacaga
    15781 ctgattttga ctatctaaaa tgacatcgaa ggtccctact tggggaagtg gttcgtcttc
    15841 tagtacatag aggtcatagg ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc
    15901 cgctaaaagg tctggttcaa ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg
    15961 attgatttgc ttgtatttat tccacatttc ttgcggtatc atgggtactc ctttgtaatt
    16021 ttttactttc ttcttttatg tgtttaagat gatctggatg gtcaatctct aaatcaaaaa
    16081 tctctggaat agaactgtag tggataatgc acttgatacc caactgattc attttttgta
    16141 tgaaagaagt attcagatag cctgctacag caaaattaat cttgttcttt cttgctttat
    16201 cctgcatatc tcttagcata tctaacatta ttggactttc cagatcatgc cattgactgt
    16261 ttctcatagt cgcaaaaaca aaggaagtca aatcattcat tccaactaca atctttgaaa
    16321 tgcccgtttc cagtatacta gataagtcaa aatacgctga cggtaattca atcatcgttc
    16381 cgactttccc agtaaagcca tactgacgca atactgtaat agcttgtttt aattggtcgg
    16441 catcattgac aaaaggaaag ataacagata gattggggtt ggtttgataa acttctgtaa
    16501 cgacatgtgc ttcagcctga aattcatcca aacacgccag taaacgcctg gttcctctat
    16561 agccaaacaa gggatgccct tcgtcaaaaa actctttagt ccccactaaa caattggctt
    16621 ctgtattcgt taattcagta aaacgatacc aaacttcttc atctgagtac agggagcaga
    16681 tagtctctag ataatctttt acaaattgct gacaacttgc taatatgatg ttttgattaa
    16741 gctctctcaa caaatattcc ccacgaatca tgccgacgtg gtgaaatagt tgaggataaa
    16801 ttttttcaag aattttttcg ccactaaggg caagttgatt tctcatagcc attcacctcg
    16861 tcttaaaaga tacaatatca tatataatta tatcaaaatt tcctctagtt caaaagcttc
    16921 ataaggttca gataactcat atcctaaaaa ttctgctact tttttggaag cctcattatg
    16981 agcatcccaa agtggaaaca tatctctatt taaactctct agaatcattg cagcaccaag
    17041 ctttttagca aatccatttc cttgttcgtt tggtctagtt gcaacttcca cttcaactgc
    17101 tttacggtaa actaaccctg aggaaatccc agcaatcagt tcattatttt taagaatcac
    17161 aaagccaaat ccacctttta aaacaaaatc ctgataggac tcaaaatccc cctgtaaatc
    17221 ctgtgaccat tcttccgtag aaaagcagtt ataaatatga ttatcaatag gcacaatatt
    17281 gtaaccttcc tctaaatgag taactagatt atttaaaaat tcaacttgaa aatttgcctt
    17341 atctttaaaa gaatagcgag taaaagaatt tagccccact tttcgatgca gaaaatcttg
    17401 ccaattagta ttttctgaaa taataatctt ataatctaaa ccatattttc taacaaaatc
    17461 ttcccaaaat ctggaatcca actcccctgc taggtataga aaattcccaa catcataaaa
    17521 gcttgttgtc ctatcattgt ttcggtagac agttccaatt tgagatttaa gaccatagag
    17581 aaccatattt ttcttccatg ttttaaatag ttccattatc cctctacttc accttccaat
    17641 tcatgtaaga agtcttgtcc agttctggaa atcctaataa ttcagactta accttcaaga
    17701 ctaatggcga tgcattttct tctgtaatct cttgaatatc catccaaata tatccaagtg
    17761 aatcattcgc accatcagac acagcttccg aagtcgtaac ttgaggtgca ctctcattca
    17821 tttcaacatc atacaaggcc atgacatggt caaccataaa atttgttaac tcttctctga
    17881 cgaaaacatc gtagattcga ggattagagt agcttctaac agtaaatccc gtctcttcca
    17941 taacttctct agtcagcgtt tccgtcagtc cttcaccaag ttgctgactg cctccaggta
    18001 gatcataccg atgttgataa gggcctctcg ttttttcaat gcagagtaac ttcccatttt
    18061 ctaagcaaac agcgtagact ccaaagtgtt ttttgatttc catccaactc ctcctacttc
    18121 aaagaccagc caccatctat tgtcaagatt tgtccttgca tggcgctcgc ttttccactt
    18181 gctaaaaaaa gactaagctc tgctatttcc tctggctcaa tccagcgctt gattggagtt
    18241 tcactagcca cccagtcagc caaaccacct ggttcaaaat ccgcagcggt catagctgtc
    18301 ttgactgctc ctggagcgat accaaagacc tgaatcccag cttcagcata gtctagagcc
    18361 aactgcttgg tgaagccagc caaggcatgc ttggatgaag tataggcgtg accacctcca
    18421 cctgctaggc tagaagcaat ggaacacata ttgatgatga ttcccttttt attttccagc
    18481 atttgtgtca aataataccg agtcaactct actggaataa tgtagttgat ttcaaaaatc
    18541 tcttgaatgt cctgcgccgt ttgttccaac agtggtttgt aatcatccaa aactccagca
    18601 gtattacaca aaacatccac ctgagggcac cagtcaaaaa taggttccaa gtccaaggtc
    18661 aaatctctct gtaaaaagtg aaaatcaccc tctaagagtg gcttttcacc ttggtcaact
    18721 ccataaactt gatagccctt ctctaaaaag aggcgagctt gagccaatcc gatccctgaa
    18781 ctcactcctg taatgagtac acgtttagtc atgcacttct acccaatccg ttgccaaaac
    18841 atcacaaact gtcgggctcc acatggaaaa accttctcct tcgccagaaa cgttgattag
    18901 gaaataaggt gtcatttcaa gtgcaagccc attttgctcg atggtatcaa agagttggac
    18961 atagttttcc gcacctcccc aaccagttcg tacatatttt ctcttagcct ttaacccagg
    19021 caggatctct tcaaatgtca tgtttttctc ctttaattct acattcttca tttaattata
    19081 gcaaaaaacc gctttatacg gctttttgaa tgtgagttat tcaaacctgc tactacttac
    19141 ggcaaattat tccctgcagc aagataaatt tcataccatt cttttcttgt taagctaaag
    19201 tttgccgctc ggctaacttc tctcaagtgc ttaggatttg ttgtacctac gactgcctgc
    19261 atttttgctg gataacgcaa tatccaagaa atggcaatag ttgaagaggt tactccatat
    19321 ttaatagcta aacgatcaag tacttgattt aaagcttgaa atttctcatt tccaacaaaa
    19381 ttccctttaa aatacccgaa ttgtaagaca gaccatgctt gaatgaccac atcgtgtaat
    19441 tggcaatatt caaaaatgct gccatctcgc atagctgctt gactatcttc catattaaca
    19501 tgaaaagctg attcaaatcc tggagtaaaa gccgcactca attgtagctg attaacagct
    19561 aacggctgct tgacatcttt tttaagcaac tccatcatca taggattttg attagaaact
    19621 ccaaaatctc gaactttacc ttgtttataa aggagattaa aggcttctgc tacttggtca
    19681 gattccatca aagcatctgg tcgatgaagg agcaagctat ctagatgatc aatcttcaat
    19741 ctttgcaaaa taccgtctac tgattttata atatagtcct tagaaaaatc aaaataggta
    19801 aattcttcaa tgcgaatgcc acatttggac tgaatccaca tcttttctct taaatctgga
    19861 cgatttttta ggacaagacc taacagttct tcacaacgac cacgaccata aatatcagcc
    19921 aagtcgaagg cattgattcc aacagaaagt gctgtttcta caagctcttc aacttctttt
    19981 acagacttat cttttattct catcattccg agaacaattt ctgataattc tttgtcatct
    20041 tgaccaagag ttatgtatct catcaaattt ttctccttta atttctaaca ttcttccctt
    20101 cattataaca aaaaaccgct ttgcaacggc tttttgacta tacttcactc cattttatct
    20161 tcttaaaccc acggaacaag acaaagattc caataaagag gacagctaaa ggaataactt
    20221 ttgtaaggaa aacatttgaa attcccatcc actcataata acggagcaga gaacccacca
    20281 caagatgggc aataatcata ctgacaaatg gacgaaagac cgcttctttc caattccaaa
    20341 taccgataac tagcgaaatc gtaaagacag acaaactatc ccagggagcc ggaatataaa
    20401 aggctccttc ttgtatgaag cttgccattc ctacatatcc taaaacaact agaagaacta
    20461 tagtcccaac aacaatgtaa gtgccaattt tcattttagg agaatcttgg actaaacttc
    20521 ttcgtaaaat tgtggccaca agtccaaatc caatcagaaa aataagaagt tgccctaaaa
    20581 atgtgagcaa attgactgtt aagagaggac ctttagaaaa atcacttagt agttgataat
    20641 aacgtaatac agccaggaca agaattggcg tcaaaaggga ctctttgata gaactgcgag
    20701 gtgctccctt gagaatctct ttcattattt ttttaggatt cttacctaga taatcctctg
    20761 cactcatgcc atctcgttct gcttctgaga aatctagcat catcaaatag atctgctctc
    20821 tgagatagtc ttcatcatag agaaatccag caagattaaa actttcccac aactcctcaa
    20881 aatacttttg attctcctca gaaaactcat gtagcaaagc gcttgtttct tcgtaatact
    20941 tcattttctt catggtttaa cccccattct taatcccttc tactttttga ctcaaatcgt
    21001 cccattgctg ccaaaagact gagacacgct cttctccttc tttcgttaat gaaaaatact
    21061 tccgatctgg accatctggc gacgggcgca tgtcgcctct tatccattga tttttttcta
    21121 acttttgcaa caaaggataa atagttcctg gaacgatagt atcaaatcca gcctctcgca
    21181 aagtctgaac caactcataa ccataccgct ctttttgacc aatcatatcc aagacacaac
    21241 cttcaagaac accttttaat agctgagttt ctttcatcac ttctcccttc taatctattt
    21301 tgtaatacct actagtaact tcacctatag tatattactt ctacactagt ttgtaaagca
    21361 taatagttaa tactcttcga aaatctcttc aaaccacgtc agcgtcgccc taccgtatgt
    21421 atggttactg acttcgtcag tttcatctac aacctcaaaa cagtgttttg agctgacttc
    21481 gtcagtttca tctacaacct caaaacagtg ttttgagctg acttcgtcag tttcatctac
    21541 aacctcaaaa acatgttttg agctgacttc gtcagttcta tctacaacct caaaacagtg
    21601 ttttgagcaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaata
    21661 aaaaaacaga actagtctga actagtcctg tctactttta cccaatcaca cttccatttg
    21721 gtacagctgg atcaactgtg agaagggtta atttgccatc atattcagct gatagaatca
    21781 taccctggct gacatatttt ttcatcattt tacgtggttt gaggttagca acgatttgaa
    21841 ctttcttgcc gaccaattct tgttcatttg gatagtattt tgcaattcct gaaagaatct
    21901 gacgatcttc tccatcacca gcatccaagc ggaattgaag caacttatct gaaccttcta
    21961 ctttagacac ttctttgact tctgcgacac ggatttcaac cttgtcaaag tcttcaaact
    22021 tgatttcatc cttgtttagt ttgagctcaa cttcgtccgg attccattct ttttcgactg
    22081 ctggtttatt gccttccatt tgttccttga tataggcgat ttcttcttcc atatttagac
    22141 gtggaaagat aggtgttcct ttggcaacta cagtcacatc tgctgggaag tcagccaaac
    22201 tcaagttttc aagactagaa acttcttcca aaccaagttg agtcaaaact gcacgactag
    22261 tttccatcat aaatggttca atcaagtgag caactacacg aatgctggct gccaagtggc
    22321 tcatgacact tgccaattgg tcacgaagag cttcatcctt ggccaagacc catggtgcgg
    22381 tctcatcgat gtatttattg gtacgagaga tcagagtcca gactgcttca agcgcacgtg
    22441 gatagtcaac tgcttccatg tgtgtatgga agtctgcgat tgattgttct gcaacctcag
    22501 caagaacatg atcaaattca gtcacacctt ctacataggc agggatttgt ccatcaaagt
    22561 acttattaat catggaaacc gtacggttaa ggaggttccc aaggtcatta gccaattcat
    22621 agttgatacg gccgacatag tcttcaggag taaaggttcc gtctgaacca actggaaggt
    22681 tacgcatgag gtagtaacga agtggatcta gtccataacg ctctaccaac atttcagggt
    22741 aaacgacatt cccttttgac ttagacattt ttccgtcttt catgacaaac caaccatggg
    22801 caatcaaacg atcaggtaat ttaacatcca acatcataag aaggattggc cagtagatag
    22861 agtggaagcg aaggatatct tttcctacca tatggaagac tgttccattc cagaacttgt
    22921 caaagttacc atgttcgtct tgagcgtagc caagagctgt cgcatagtta agaagggcat
    22981 caatccaaac gtagacaacg tgttttggat ttgatgggac aggcactccc catgtaaagg
    23041 ttgtacgaga taccgccaaa tcttccaagc ctggctcgat gaagttgcgt agcatttcat
    23101 taaggcgacc atctggcgtg ataaattcag gatgagcttt gaaaaattcg accaaacggt
    23161 cttggtattt gctaaggcga aggaagtatg attcttcaga aacccattca acctcatgac
    23221 ctgatggagc aataccacca gtcacatttc cagcttcatc acggaaaact tctgccagct
    23281 ggctttctgt aaagaattct tcgtctgata ctgaatacca accagagtat tcacccaagt
    23341 agatatcatc ttgagcaagt aagcgttcaa agacctgtgc gacaactttt tcatggtagt
    23401 catcggttgt acggataaat ttatcgtatg agatatctag taattgccag agttctttaa
    23461 ctccaaccgc cattccatca acataggctt gaggtgtaat accagcttct tccgctttct
    23521 gctggatttt ctgaccatgt tcatcaagac ctgtcagata aaatacatcg tagcccatca
    23581 ggcgtttgta acgtgctagg acatcacatg cgatagttgt gtaggcagaa ccgatatgaa
    23641 gtttcccaga tggatagtaa atcggcgttg taatataaaa atttttttca gacataattt
    23701 ttcctttcca ggcaaatgaa acctgttttt ctaacacttc attatatcac atttttaatg
    23761 aatttcgata gggaaatcca tacaaaaaca agatagacga gtgtccatct tgttgatctc
    23821 attcataacg aagggcttca attggatcaa gtttcgatgc cttgttggct ggcaagactc
    23881 caaaaatcat accaacacta gccgaaactg caagactaaa tagggcaact gggattgata
    23941 ctccaacttc tataccttct attaaacctt gcagtaacaa acctgctaag gcagttaaac
    24001 cacttgcaat tgtcaagcca attaagccac ctaacaaggt caaaatcatg gattcaatca
    24061 aaaactgaat taaaatattg gcacgtgttg cacccaaagc tttacgaaga ccaatctcac
    24121 gagtgcgctc tgtcaccgaa accagcatga tgttcatgac accagttcct ccaacaaaga
    24181 gagaaatccc tgcgatggaa ctaataatcg tcgtcataaa actaaacgat tgttgaattt
    24241 ctgcaaatac aacggactca tctgccacct ggtattctcc ctgttgtaag cctgcaagct
    24301 ctgtcatttt tcgtgccagt tctggaccca gagttggggt taaactggta tcattcactc
    24361 gaaagacaat actagctatt tcatctatat taaaattcgc agcaagggag atattggtag
    24421 taataggcaa gccaccaaac ccatatattt ttgacttttt agcctccgga ctagtataaa
    24481 ccccaatgac ccggtaacta aatccattga cttctacaac cttgttaata gcctcttgag
    24541 gagattcaaa taaactaatg gacaattcct catctagcaa aataacactt gcaaactctt
    24601 tgaaatcttg ctctctcaga ctacgacctg caataatttc attcttaaca gcgtccatgt
    24661 aagttctgtt tccacctgtc aaattagcat tctcaacctt tttatcttga taggtcaaga
    24721 tggcattcgt tgaattggtt acatagtaac tatccactcc cttcagttta gctgcctctt
    24781 gaacccagga ttcttgcggt tttggcggtt caacaggaac ttcctcttcc tttccagaaa
    24841 ccgtaaaagc tgattgtttc tgagtaaaag acccatcttt acttttttta ggagagaaaa
    24901 agacgctaat atttttctga gatttagtca tatctttatt gacttgacga gatagggaat
    24961 cacccaaagc cataatcaca acaactgatg aaacaccgat aataatccca atcatagtaa
    25021 gcaaagaacg catcttgtga gccatgatag atgaaaaggc aaatttcaga ttctgcatct
    25081 tagttttcct cctttcctaa ctgagcactg tcagacgaaa tgaccccatc ccgaatgaca
    25141 atctgacgtt tggcataggc agcaatctca ggctcatgcg ttaccatgat aatggttttt
    25201 ccttctttat tcaaatcaac caataattgc ataatttggt tacctgtttt ggtatccaag
    25261 gctcctgtcg gttcatccgc taggataata gaaggattgt ttaccaaggc acgcgcaatg
    25321 gctacacgtt gcttttgacc accagataat tctgaaggta aatggtgact acgttctgtc
    25381 aattcaacct tgtctaaata ttcctcagcc aacttgcgac gttttgaaga cgaaactcct
    25441 gcgtaaatca agggcaattc tacattttgc agagcattga gcttcgatag aagaaagaac
    25501 tgctgaaaga caaaaccgat ttgttggtta cggaccttag ctagttgttt ttcaccaagc
    25561 ccagccactt cttgaccttc aagataatat tctccactgg ttggtgtatc caacatgcca
    25621 atcgtattca tcagagtgga cttaccagac ccagatggtc ccatgatggc tacaaattca
    25681 ccctcattca cttctagatt gatatttttg agaacctgca gttcttggtc accattacgg
    25741 taacttctga agatattttt tagactaatt agttgcttca tcagccttca cctcttttcc
    25801 ttcttccaag gaagatgttg gattactgat gaccttagca ccgttcgtta aaccagaagt
    25861 gatttcttga ttttctgcgt cagcatttcc caatgaaacc tcaacttttt tagccttttg
    25921 ttgttcatcc acaatccaga cataattttt actatcatcc attactagac tgctaacagg
    25981 aataagaata gccttagttt tgcttttaac ctcaatgttg acagaaaaac cttgtttcaa
    26041 atcaccaacc tcgcctgtca catcaatagt ataagggtat ttagaacctg tattattccc
    26101 ggctgctgga ctagctgctt caccattgtt tttaggatag tcagaaatat agcttaattt
    26161 cccagtccat tttttatcag gatacacttt agaagtaaag cttacttctt gacctacaga
    26221 aaggttggct agattgtact cagacaattc tcccttgact tgtaaatttt cattgctgac
    26281 aatatgaacc ataacttgac tcgcccctgt tggagattta gaaacattgc tattgacttc
    26341 gactacagtt ccctctaggg tactgagaac agttgttgca tccaattgac tttgagcctt
    26401 gcttaattgc gctgcagcat ctgcacgcgc atcacgggca tcacccaatt gagcatcaat
    26461 agaagcaaca gaatttccag ccactggagt tgggctttgc accgttgcat cttctcctcc
    26521 tactggcgct ggtaactgtg gagcctgagc tgaagcggct tcatttcgtg cttgattgag
    26581 ttcattgata tgacgatctg ccttagctac tgctcgacta gctgaatcat aggccgcctg
    26641 cgcttctgaa ctactgtact tgactaaagc ctgcccttcg ctgaccttat cgcccacaga
    26701 aacaaggatt tcatctaaat cacccttact agcatcaaaa taaacatatt gttcattttt
    26761 tgctgttact gtccctgaca ataaaacaga ggatgccacg cttccttcct tggcaacaac
    26821 aagatgagta ggctcatctt ttacagcagt ctgagaaggt tgtctaaaaa gtaaaatccc
    26881 cccggcaccc aatacaacta cactcgcagc accgattgct gcatacagtt gccacttttt
    26941 agctttacca ttctttttct tcataatgaa actccttttc ttttttacaa tactttgcta
    27001 ttataccaaa tttccctcca gcaaacaatg cagttcagat ggaaataatg gcagttcagg
    27061 attaaacaat cgttcggaat tttgcttttc tattgtacta gatatataat acactatctt
    27121 gacttatttg gcaagctttt ttgcaatttt ttgtgcgtag cagatttttg caatcaaatc
    27181 aaaaaaagaa taaaatataa ctatcaaaaa agacactcta ctatttaaaa gattacaaag
    27241 gagttttcaa tgagagaata tgatatcatt gctatcggtg gaggtagcgg aggaatcgct
    27301 accatgaacc gtgctggtga acatggagcc aaagcagccg ttattgagga aaagaaatta
    27361 ggtggaacct gtgtcaacgt cggttgtgtt cctaaaaaaa tcatgtggta cggggcgcaa
    27421 atcgctgaga ctttccatca atttggagaa gactacggct ttaagactac tgatcttaac
    27481 tttgactttg caaccctacg tcgcaatcgt gaagcctaca ttgatcgcgc tcgttcttct
    27541 tatgatggta gttttaaacg caacggtgta gacttgattg aaggtcatgc tgaatttgta
    27601 gattctcata ctgtaagcgt aaatggtgaa ctgattcgtg ctaaacatat cgtgattgct
    27661 acaggtgccc atccaagtat tcctaatatt cctggtgctg agctaggtgg ctcttctgat
    27721 gatgtatttg cctgggaaga acttccagag tcaattgcca ttctaggcgc tggttatatc
    27781 gccgttgaat tagctggcgt actccacact tttggtgtca agacagatct ctttgttcgc
    27841 cgcgatcgtc ctttacgtgg ttttgattcc tacatcgttg aaggtttggt caaggaaatg
    27901 gaaagaacaa acttaccact tcacactcac aaagtccctg tcaagttaga aaaaactact
    27961 gacggcatta ccattcattt cgaagatggt actagtcaca cagctagcca agttatctgg
    28021 gctacaggtc gccgtccaaa cgttaagggc ttgcaacttg aaaaagctgg agtgactctg
    28081 aacgaacgtg gctttatcca agtggatgaa taccaaaata ctgttgttga gggaatctat
    28141 gctctaggtg atgtaacggg cgagaaagaa ctgactccag ttgcaatcaa ggccggacgt
    28201 accctatctg aacgtctctt taacggaaaa actactgcaa aaatggatta ctcaactatt
    28261 ccaactgttg tcttttcaca ccctgctatc ggaactgttg gtttgacaga agagcaagct
    28321 attaaagaat acggtcaaga ccaaatcaag gtttataaat caagctttgc atctatgtac
    28381 tctgcttgca ctcgcaaccg tcaagaatcc cgtttcaaac tcataacagc tggttcagaa
    28441 gaaaaagttg tcggacttca tggaattggc tacggcgttg atgaaatgat tcagggattt
    28501 gccgttgcta tcaaaatggg agcaaccaag gctgactttg atgcaactgt ggcaattcac
    28561 ccaactgcat ctgaagaatt tgtaaccatg cgttaatcga aacaaaagaa gctgatataa
    28621 atatgtctgc ttcttttt
//
LOCUS       DAVBED010000026        27272 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBED010000026 DAVBED010000000
VERSION     DAVBED010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.026"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            225..1907
                     /locus_tag="VQ547_001112"
     CDS             225..1907
                     /locus_tag="VQ547_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542969.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1892..2722
                     /locus_tag="VQ547_001113"
     CDS             1892..2722
                     /locus_tag="VQ547_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2542970.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2915..3418
                     /locus_tag="VQ547_001114"
     CDS             2915..3418
                     /locus_tag="VQ547_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2542971.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3472..3706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3871..4434
                     /locus_tag="VQ547_001115"
     CDS             3871..4434
                     /locus_tag="VQ547_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2542972.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4448..5074
                     /locus_tag="VQ547_001116"
     CDS             4448..5074
                     /locus_tag="VQ547_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2542973.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5186..6058
                     /locus_tag="VQ547_001117"
     CDS             5186..6058
                     /locus_tag="VQ547_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2542974.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6188..6325
                     /locus_tag="VQ547_001118"
     CDS             6188..6325
                     /locus_tag="VQ547_001118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542975.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6749..7663
                     /locus_tag="VQ547_001119"
     CDS             6749..7663
                     /locus_tag="VQ547_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2542976.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7656..8669
                     /locus_tag="VQ547_001120"
     CDS             7656..8669
                     /locus_tag="VQ547_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542977.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8653..10245
                     /locus_tag="VQ547_001121"
     CDS             8653..10245
                     /locus_tag="VQ547_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2542978.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10437..11340
                     /locus_tag="VQ547_001122"
                     /pseudo
     CDS             10437..11340
                     /locus_tag="VQ547_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11358..11495
                     /locus_tag="VQ547_001123"
                     /pseudo
     CDS             11358..11495
                     /locus_tag="VQ547_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11523..11864
                     /locus_tag="VQ547_001124"
     CDS             11523..11864
                     /locus_tag="VQ547_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542979.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11837..12148
                     /locus_tag="VQ547_001125"
                     /pseudo
     CDS             11837..12148
                     /locus_tag="VQ547_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12276..12863
                     /locus_tag="VQ547_001126"
     CDS             12276..12863
                     /locus_tag="VQ547_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2542980.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13253..14860
                     /locus_tag="VQ547_001127"
     CDS             13253..14860
                     /locus_tag="VQ547_001127"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2542981.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15419..17050)
                     /locus_tag="VQ547_001128"
     CDS             complement(15419..17050)
                     /locus_tag="VQ547_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2542982.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17343..22322
                     /locus_tag="VQ547_001129"
     CDS             17343..22322
                     /locus_tag="VQ547_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2542983.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22412..23608
                     /locus_tag="VQ547_001130"
     CDS             22412..23608
                     /locus_tag="VQ547_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2542984.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23744..24271
                     /locus_tag="VQ547_001131"
     CDS             23744..24271
                     /locus_tag="VQ547_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2542985.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24348..24704
                     /gene="glnR"
                     /locus_tag="VQ547_001132"
     CDS             24348..24704
                     /gene="glnR"
                     /locus_tag="VQ547_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2542986.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24741..26087
                     /gene="glnA"
                     /locus_tag="VQ547_001133"
     CDS             24741..26087
                     /gene="glnA"
                     /locus_tag="VQ547_001133"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2542987.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26183..26302)
                     /locus_tag="VQ547_001134"
     CDS             complement(26183..26302)
                     /locus_tag="VQ547_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2542988.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26790..27272
                     /locus_tag="VQ547_001135"
                     /pseudo
     CDS             26790..27272
                     /locus_tag="VQ547_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8592 a         4568 c         5792 g         8320 t
ORIGIN      
        1 catacctacg gcaaggcgaa actgacgtgg tttgaagaga ttttcgaaga gtataaaatg
       61 atggggaagg ctgggcaact agtctttttc gatgtttata gattagttag gcaagtaagc
      121 taggatagga atctttttgg tgctaagatt ttaagagaag agactgcaag aagggcttga
      181 tttatgataa aatagaagtc taagaagcga atgaagagag taagatgaaa gaagctataa
      241 ttgagtggaa ggatttctct ttccggtatg aaacacaaca agaaccgacc ttgcaaggga
      301 tagacttgac catttacaag ggagagaaag tcttaattgt tggaccatct ggatcaggta
      361 aatctacctt gggtcagtgt ttgaatggga ttattcccaa tatttacaag ggtcagacat
      421 atggagaatt tttgataaag ggtcaaacag cctttgatat gagcatctat gataagtctc
      481 atctggttag cacagttttg caggatacag atgggcagtt tattggcttg tctgtggcag
      541 aagatttggc gtttgctctg gaaaatgatg tgacagccct agatgagatg aaaggtcgtg
      601 tttataaatg ggctgaaaag ctggaccttc ttcctttact ggatcagcgt cctcaggatt
      661 tgtcaggtgg acaaaagcag cgagtcagtc tggctggtgt cttgattgat gaaagtccga
      721 ttctcttgtt tgatgagcca ctcgccaatc tagatcccaa gtcaggtcag gatattatcg
      781 aattgattga ccagattcat aaggaagagg ggacgacgac tcttattatc gagcaccgtt
      841 tggaggatgt tctgcatcgc cctgtggatc ggattgtctt gataaacgat ggtcgtatcc
      901 tttttaatgg gagccctgac cagttgcttg cgactgattt attgactcaa aatggaattc
      961 gagaacccct ttatctaacc actctccgtc aattaggtgt ggacttagtc aaggaagaac
     1021 agttagcgaa tctggataac atgtctatct caaaaggtca ggttcagctg cagaatgaac
     1081 tggtaaaaga aactccagaa ttgcagtcac tctttaaatt agaggacgtg tctttctctt
     1141 atgatgatag accgatttta aaatccctac atttagatat taaaaagggt gaaaagattg
     1201 ctattgtcgg aaaaaatgga gcagggaaat caactctagc caaggctata agtagcttta
     1261 ttcagacgga aggacgctat ctttgggaaa aacaggatat aaaaggcgat tctgttgcag
     1321 agcgggcgga acgagtaggc tatgtgctac aaaatcctaa tcaaatgatt tcaaccaata
     1381 tgatttttga tgaggtggct ctagggctcc gtttgcgagg tgtggatgag aaggaaattg
     1441 aaacgagagt ctatgaaacc ttgaaaatct gtggacttta tgaattccgt aattggccta
     1501 tttctgccct gtcatttggt cagaaaaaac gtgtcaccat tgcttcaatt ttggtcttag
     1561 gagctgaaat tattctccta gatgaaccga ctgcaggtca agatcagaag aactatactg
     1621 agattatgga atttctcgaa gagttacatc gaaaagggca taccattgtc atgattaccc
     1681 atgatatgca attgatgctg gattattcag accgagtcct tgtcatggtg gatggagaat
     1741 tgattgccga tactgttcca gccagtctgt tgagcgatcc tgagctgtta gtaaaagcca
     1801 atctaaaaga aacctccatc tttaacttgg ctaagaaact agatgtggat ccactggatt
     1861 taacggcatt ttacaaagaa aggagagagg gatgcaagct aaattaatcg gttaccagca
     1921 tagagatact gtgattcatc gcttgtcagg agctgggaaa cttctctttt tcattctggt
     1981 atcattggcg gccatgatta gctatgatac cagaatgctc ttgctgattg ccatcttttc
     2041 agtctttctc ctctatttat cagaaattcg ctttaaagat gtttcctttg tagccgtttt
     2101 tgcgacggta tttgccgttt taaacgtttt gatggtctat ctcttttctc ccgagtatgg
     2161 ggttggactt tatggagaga gaagtgtgat ttggcaggga atcggtgtct acactctaac
     2221 cagccaggag ctcttttatc tgctaaattt ggccattaag tatctttgca ccattcctct
     2281 ggctattatc tttttgatga caacccatcc tagtcagttt gcttccagtt taaatcaaat
     2341 tggtgtgccc tataagattg cttattctgt cagcctgacc ttgcgctata ttccagattt
     2401 gcaggaagaa ttctttacta tcaagatgtc tcaggaggcg cgtgggatgg aattatccaa
     2461 gaaagcttct cttatgcaac gaatcaaagg caatctgctc attattacgc ccttgatttt
     2521 tagctcgcta gaacgcattg ataccattgc gactgccatg gagcttcgcc gctttgggaa
     2581 agaaaaaaaa cgcacatggt atagttatca ggccttgaaa aaaggagact atattacctt
     2641 gctcttggca accttgtttt tagtagctag tttactactt agcttgcaga atcagggacg
     2701 attttacaac ccttggaaat agcttgaaaa aattgaaaaa atcaagtcgt ttctattgac
     2761 aatgattctg aaagtgttat actaagaaag tagtttcgct gatttacttc aaacctgttg
     2821 tgaggtaagt taacgatgcc ttaaccacgc tgtttgctga gcttgactcc gggcagtgtg
     2881 gctatttttt tgcaatggtg aaaggaagca agtcatgaca aatcacattg tattatttga
     2941 acctcaaatt ccacaaaata cgggcaatat cgcgcgtact tgcgctgcga ccaattctcc
     3001 cctccacatc atcaagccta tgggctttcc tattgatgac cgcaagatga agcgggctgg
     3061 attggattac tgggataagc tagagattta tttttacgag agtttggaag atttcatatc
     3121 tcagatgaag ggaaaactct atctgatttc gaaattcgcg gaaaaagtct attctgaggt
     3181 ggatttatcg actgacgagg accattattt tctctttgga cgtgaagaca agggcttacc
     3241 tgaagatttt atgcgagaac atcctgagaa ggctctccgt attcccatga atgatgaaca
     3301 tgtccgcagt ctcaatgtgt ctaataccgt ctgcatgatt gtctatgagg ctcttcgcca
     3361 gcagaacttt gcaggtcttg aactcgtcca tacctatgaa gtggataaat tgaaataaaa
     3421 aatgaaaatg aacaaaatgc ttgcgcttgc aagcgttttt tgttatgata aaagagtctt
     3481 cagggcaggg tgtgattccc gaccggcggt gactttaact aggaaatgat cttttccttt
     3541 tatactttgt tgacaagctt tgcctaacca gaagttatgc ctacagcttg tcgcctagtc
     3601 taaaagaaaa atctctattt ccttctcttt aaagaagtcc gcgagcgcaa gctgatgtgg
     3661 tgagattcca caaccgacag tatagtctgg atgggagaag acgaaagaat agctttgtct
     3721 gttttgatag atttatagcc ggattgtaac cacttgcttt gtttttcttt aatagagtag
     3781 gagggaactt ttgggatata aaaagtgaga atagatagag gaatcctttc caacttcttc
     3841 tgattttata gaaaattgga ggaacctgtt atgacaaaca cacgtcgact ttcgaccatt
     3901 gcaattttat cagccatctc atttgtgctg atgtactttg actttccgct tttaccagcg
     3961 gcatctttcc tcaagatcga atttagtatc ttgccagtcc ttgtgggtct ggtggtcatg
     4021 gatttgcctg ctgctctagg agtgctcttg cttcgctcac tcttgaaatt gcttcttaac
     4081 agccaaggag tgaatactta cattggtttg ccgatgaata tcgtagcttt gggagttttt
     4141 gtcatcgtat ttgctttgat ttggaaaaag gaacggacaa cccttcgttt cctactaggc
     4201 tctctagctg ggactattgg tttaaccgtg gctatgttag ttctcaacta tgtttatgct
     4261 gttcctttgt acgctaagtt tgctaacttt gatattggaa aaattttggg actttccaac
     4321 tacctaatga ccatggtatt accttttaac ttgattgaag gtgtaatctt ttccgtttca
     4381 ttctggttgt tgtacattct cttgaaacca accttaaaac attatgaaag ataaacaaac
     4441 atttttaatg aagggcagtt ttgccctttt acttttcgtt attcttggct atatggtcaa
     4501 attttaccct gaaatgttgg tcaattttga ccaatcgatt cagactgcca ttcgaggaga
     4561 cttaccagat tatttgacta ttctttttcg atccctcaca cgtctgattg atattccagt
     4621 gattatcact tgggttgtca ttatagcttt tgtcttttat cgtaagcgat ggaagataga
     4681 aagtttcttc atgctgggaa atctgacttt ggcaggtctt ttaatcgtga cctttaaaaa
     4741 tatctaccag cgcccacgac cagctatctt acatctggtg gaggagaagg gattttcctt
     4801 cccaagtggg cattctctgg ctgtaacgct gatggtaggg actttgattg ttattcttag
     4861 tcagcggatt aaagatcagg tctggagaaa aatcgtacaa atcgtccttg gcctctacct
     4921 agtcagtgtg ctggtatcaa gagtctatct gggagttcat tacccatcag atgttcttgc
     4981 cagtctctgt gtgggcttgg gagccctgtt tatcgagttt cccttttatg ataagctccg
     5041 cttccaatgg cgatttaaag gcaaacagaa atgatggaaa agataaaaaa ttgtacaaat
     5101 acaaatagaa ccatatgaaa tatatacttg aaacatgttt tggagtttga tatattttaa
     5161 taaataaagc aaggaggaag aaagtgtggg tatgttatta gcgacacgct taaaaaataa
     5221 aagaaaggaa ttaaaattat ctcaaaaaga attagctgag gggatttgtg agcaagggca
     5281 gattagccgt atggagcaag gtaaatactc acctgggtca gaattactct ttcaactatc
     5341 taagcgattg aaggtgagca tggattattt ctttgaagat actgaggttt ctagtttaga
     5401 aaatattgat aagtttaaag aattatctaa gaaatttttg gatgagaggg aatatgaatc
     5461 tctccattac atctatgaac tggaaaaatc taaacgtgct cgtctatctg ctaaagacca
     5521 gatttatttg gattggattg atacattagt tcaattctgt tatttaaatc atcaaacagg
     5581 ggcagttgcg aaactggaaa aaatactgtt atctctgaaa aaatctgatt tttactatct
     5641 acaactggga aataccttgg ctaattttta ttttgatatg gggcaggaag acacatatca
     5701 ggaactctat caacttttaa aagagaacct ccagtcacta tctgttcatc atttggaaca
     5761 gttagaattg atgattaaat tccgatataa ctattgtaga tatttgtggt tgaatgaacg
     5821 aacatctgaa gctatagaag aaattacaga aacgatagct atttgtaaaa gatataatag
     5881 tagttatcga ttagcagatt tgtattgttt attgggaagt ataagcgagg gctttgctga
     5941 aagggatagg atactaggtt tttatcaagt atcttaccag ctttacaagc acgaagagaa
     6001 ccagagaatg atgctagaaa ttgagaagga aatgaaatta ttggaaagtg aagattaagc
     6061 aaaaagattt gtattcttag ataactttaa tacatattat aaaaaaaata aaaaaatatc
     6121 ataaaaatta ttgacaaacc aaaattgatg tgttagaata tcaccaatag ttaaggaggt
     6181 ttagaagatg aaaagatctc aagttgtcaa acgatgtata ttaattgctt tattgcttct
     6241 atttctactt aatgtgttaa gtggttcttt atctgtaaca actagaggag ttgatccaag
     6301 accagcatat ggagtttcgc tttaaagttg tgcatagttc ttcttttata gacggagagt
     6361 ttttctcaat agtaagtgat tcaaattttg atggatgatt ttccattaaa ttaagtgatt
     6421 gcgaaaactt tttgaaatac attctctttg gatattgaaa gtttgttttg gattttttta
     6481 tgaagcttat cttagctgtt agattggggt tttatgggat ttgtcctcac cgggaaaaaa
     6541 tcttaaatct ttgaagaaag aggtttttat cttatggtta gagatacatc agaagaaatt
     6601 gaagttattg acttgtcttc tatgaccgtt tcctactcat ctgttatgct aggaaactct
     6661 tggatgacgt ggaattgatt tattaagata gattatttgg tttttaccaa aaatctgtct
     6721 ttttaatttt taaaggacta atggtgatat gaaactatat caaataaatg atgggataca
     6781 aatttttgaa agtagtaatc ttgaaaaaat agtaattaga aattatagga atggtaagaa
     6841 aataactatc gatcaccaac cattattaaa aaaattacta ctattccttg aagttcctaa
     6901 acgtgaagaa gaaattctat tatatcttcc agaattatca aataaaacat tacgaagtgt
     6961 tttgacgaat tttatgagtt taaatataat tcattgtcaa gatacattaa taattcacaa
     7021 aaaaataaac atattgataa taggtttagg gactacgggt ggatatctgg cagatgggtt
     7081 atgtcgtagt aatattaatt cgaagctatt tcttttagat aaggatcgtg tagatgagac
     7141 taatgtaggt agacagattt atttaagaga tgatattggt caatataaag ttgatgtatt
     7201 taaacaaaag tttagtgata aagaaataaa ggtattcaaa atttttatta atagtaagaa
     7261 agatttggaa aagatttgca aaagggaggg tatcgatttg gttatacaat gtggtgactc
     7321 cccttcacct cgagaattag gaaaaattgt gaatacagta tgtgatactc tccagatacc
     7381 ttatatagtt aacactggct acatgagtaa tgtagttcct ttgccagaat tttattatcc
     7441 aaataataga tacaatttta attataagca tcaattttca gatgaaaagt tactgttctc
     7501 acaagttttg tctaaagctg attatatggt ggcaattcaa tcatcatttg taatgttaat
     7561 gcaaataaaa aattttatat ttaatgaaga acctatttat tatggttata ggggatacta
     7621 taattctgta acattagcat gggaggtgga aaaaattgac taaatattta gaattggatt
     7681 attctcattc atatattttg gaaggtttta gaaaaaatga tgcgtttatt gaaaatcaca
     7741 aagaatgcct tgatatgtta tcagataaga tttggcgaga taataaatat atgaatacag
     7801 aaaaaaacat atcatcaccg acacgaacaa tcttatcacg ctatacttgt aatattttat
     7861 cgtctttgtt tattgatatt agcaaaaata gcatagaaaa attgatagtg acatgtgaaa
     7921 atagcgatct taattggatt tataattatt ataaatcggt ttacaatgga gtattttgtg
     7981 aattgcgaca acttatacaa cagtactgta aggtgaagga taagtatgaa aagtggcttt
     8041 ttataaaagc tattataaat caaggtattc gtcaaaatga gaaagaagtt gttgaattct
     8101 ttttaaaaca attgaaggat aataatcaag gtatttttga ttacatcaat agttttagtt
     8161 tttatctatt aaagttttat tcaaaagaca aatctcgcat ttttttagaa gagcagctag
     8221 atatagatga ttttttggga tcagataaag aagattatgc taggtcttta gtttttaaga
     8281 attatgcttc tctattgcct gatacttctg aattaaaaag aaatattatg gaaaaatgtt
     8341 taagtcaaac acctcaagat acagatttat ggaaagaatg gtttgaaact tatgccagtc
     8401 agaaagagat tagacaaaaa gcaacggaaa tatttaagca tggttattca gatatttcgt
     8461 tactaaaatt agttaaaatt gagcctgatg acactgagag tttaatcaga atgattatct
     8521 tatgtaccag tgacctaaat agtaatattg caaggtattt gatttcattt ttgagcgatg
     8581 ggcgattaaa agaatttttg gagttatttg ttgaaaattt tgactttttg aatattattg
     8641 agggaaaaac tagtgagatt aatttttaga ataattagaa aagatattat attatattct
     8701 atattaacat ttttgctatc aatagcgatg gtaagcgaag catttttgat gcaatttatt
     8761 gttgattcaa ttaaatttgg tgaaaagaag tatgttttga tttctatttt tattgtaatt
     8821 tttttgattc ttcagacttt attgtattac tatcaacaat ttcttacagc tgtattaagt
     8881 aaaaaatctg catatgagta ccgtaaatta atttttaaaa atattcagca gacttctctt
     8941 aggcttgtta caggtgaaaa aaatgatagt attctagctt ctttgacaac gcaaatcgat
     9001 caaatagaat ataattattt ttattctgtt tattggggtg gatatttgct ttgccaatta
     9061 gtggtagcta tagttatgtc gctttatcta aatccattga tgtctgtatt aaccatttgc
     9121 ttaagtctcc ctaatttatt tgtagcactt ctttttaaaa actccttgga acaaaagcaa
     9181 gaagagctaa ttaatgagac aaattcctca atagcagtta ctcaagattt aattgaggga
     9241 attactgatt ggaaaattgc aaatagagaa cctaatatat ttagagtgtt tgaaagcaaa
     9301 acattgaagc ttttagagaa gcaagtgaag gtagaaaaat ttcaatacat tgttgttagt
     9361 ttaaatcaat tgttttcaaa tgttttatat tttggtagtt ggatagtagg tggattcttg
     9421 attatacggg ggcaactttc attagggagt ttgatagcgt tctctcaatt attagcaaga
     9481 atttcttacc ctgtttacgc ttcttcggat ttattgtcaa aatatattag cggtaaaaaa
     9541 attgtagaaa ttctttctaa agaatttata ttttcagacg aaagcagaaa ttatccagat
     9601 gagtttaatg ttatttcatt tgaacattat tttacaaaca ttgacgaaaa ggatatgcct
     9661 tttgataaag aattttacaa aaataaaaaa tatttgttga aagggaaaag tggtagtggg
     9721 aaaacaacaa ttttaaaatc gattttacga gagtatgatg attatagtgg aattgtaaaa
     9781 attaatgggg tagatgttag ggatataaaa gagagtgttc tttttgacaa tatagcttat
     9841 gtttcccaaa aacctcactt gttcagcgca agtcttagag acaacctgac attattttct
     9901 gaagacttca ctgataatga gatagttgag gttttaaaat ttgttgaatt atctaaatgg
     9961 gctaataaag attgcttgga tatgatgctt tcaaatgatg atataaaatt atcaggaggg
    10021 gaggtcaaaa gggtttcttt agctcgagcc ttattgatga ataagaatat tctgttattg
    10081 gatgagttct ctgctgggat tgattatgaa acattgttaa aaatagagaa gaaactcatt
    10141 gatttggata agatgattat ttacgtgacg catgtggata tagatagatc cggcaaacag
    10201 tttgatgatg tcattgattt ggattgtctt tttatatcct cgtgacatga gagttgagtc
    10261 agttgaatta ttttgtcact ctgtttagtt cttgttggta gtgtcaggta atctttgtta
    10321 atttttcagg aagtctattg aaatatcctc ttggttatat attacgagga gtaattaatg
    10381 gatattctcg agaattcaat acaacaattt gattctaaag ttaagtatgt ttctttattt
    10441 gcggaatcaa tcttttatca gataccatga gctattttgc aggtgctatg atttctcctt
    10501 tgtatgtgag gattatcgga gatgatatga cagatgctat gggggttaga caggcaactg
    10561 ctggtgtagt taatattctc agcaacctta tagggggagt tttgattggg ggtcatcagt
    10621 cttcagatgt ttgtaggttt gaatgctttg acctttcttt ttgcactgtt gggtgtggtg
    10681 tttattcgta cttctttgag agatattgag gaacagatgg aggttagtaa aagattagcc
    10741 gcaaaatctt ttggagagca tttcctccat tcaatgaaga tattgtcaag ttttccagcc
    10801 atcatcaaat taatattcat tgcagctatg aaccaagtga ttttaagcat tattatccct
    10861 ttaacgactt tgatgttaat ccatcatcca tttatcttct ttgacactgg gaaatccatt
    10921 gcagcattgt cagtggttat tttttcagga acgattgtgg gaagtttttt gagtggaggt
    10981 atcctaaaaa atattcccat aaaaatgatt gtctactttg aagaaattat gcatctctgt
    11041 attctctttt cttggttgac caatcatttc ctccttttat tggtagttgt cttcttatgc
    11101 gcagttgcag taggaatgat ggggcctcgg attttcaacc ttgtattctc gatggttcca
    11161 gaagaagtca tgggaaccat ccagtcagtg cttggagtat tcaatgttgt tgtaccagga
    11221 attcttagca tgctcatcgt tgccttagcg agtgctacaa acctaaaaat cacagtgctt
    11281 ccacttttta tttttgtatt gactgcctta gcaattgtga aagcaatgaa aatagagtaa
    11341 tagtagtatg aactactgtc tctttttggg tgggagttca ttacccatca gacgtccttg
    11401 ccagtctctg tgtgggcttg ggagttttgt ttatcgagtt tcccttctat gacaagctcc
    11461 gcttccaatg gcgatttaaa ggcaaacaga agtgagtatc gaattccctt gaggagaaag
    11521 aaatgaaagt caatatagca gatcttcatc cgactcaact atatttatca gaaaagaagt
    11581 tgcaagatat tcagatgctt taccagtcgg cagaaacaat ccaagtcgat ccaatcagta
    11641 ttcttgcctt tggagattgt ttgctgatta cagatgggca tcacagggct tatcaggctt
    11701 tattggcagg tcgggatacg atttctgctg agtgggatag agatggtggt gatgaactat
    11761 atcatctcta tgcgcaagct tgcgaggaaa gaaagattta ctctgttttt gatttaaaaa
    11821 atcatatctt acctctttgg atcggcatgg tgagcttttt ttgattgaag tcaaggagaa
    11881 gggagaatgg tttccaattg gggatattac actatctcag gataatctcc ccattgtgat
    11941 tgggaattcc gcttaccaac atcgaggact tggaaaaaag attctaagtg ctttgattga
    12001 attggctcga gtaaaaggat ggaaagaatt gagagtcaag gaaatctaca cctacaatca
    12061 tgcttctagg aggtgtttca agtcgcttgg atttgtggaa aatggagcaa cagaaaaagg
    12121 aaggagtttt atattggaat tagtctaatc ctgccacttt ctccccctta acctttgact
    12181 attccgcaaa attatcgtaa aataaagagt aaatgataaa atgaggtcag agtctgttcg
    12241 ctctgacgat agtagtataa atgaggagaa acgctttgga attagaagta tttgctgggc
    12301 aagaaaaaag tgaactatct atgattgagg tagcgcgtgc tatattagaa cttcgtggtc
    12361 gcgatcatga gatgcatttt agcgatcttg taaacgaaat tcaaaactac cttggaacat
    12421 caaacagcga tatccgcgaa gctttgcctc tgttctacac agagttgaac tttgacggta
    12481 gcttcatctc acttggggac aacaaatggg gtcttcgttc atggtatggt gtggacgaaa
    12541 tcgacgaaga aatcatcgct cttgaagaaa atgacgacga tgaagtagca ccaaaagcta
    12601 agaaaaaacg tgtcaatgcc tttatggatg gtgattcaga tgccattgac tacaatgcag
    12661 atgatccaga agacgaagat gcatacgaag cagatccagc tctttcatac gatgatgaaa
    12721 atccagatga tgaaaaaaat gaagtggaag cttatgatgc agaaatcaac gaaatcgctc
    12781 cagatgactt gggagaagat gtggatctca acgaagacga cgacgagttt tcagatgacg
    12841 acgctgaaac cagcgaggaa taagagttag ctattgacaa ttatcctatt tttaggtatc
    12901 atattgtttg ggcacctctt ttagaggtcg gggctcccta gttcttaggg agctattttt
    12961 gttttttcaa gaagttatct tcttgtattt tatactcaat gaaaatcaaa gagcaagcta
    13021 ggaaactggc cgtaggctgc tcaaaacact gttttgaggt tgtagataag actgacaaag
    13081 tcaggaacac atatctacgg caaggcgacg ttgacgcggt ttgaagagat tttcgaagag
    13141 tattagttgt gaatctggtg cagtcgtccc agattattct tattagtagg gtcttgtttt
    13201 ctatatcccc tcgtagttaa caagaccttg agcattttag aaagaggaat ctatgtctac
    13261 gaaatatatt tttgtaactg gtggtgtggt atcgtctatt gggaaaggga ttgtggcagc
    13321 gagtctaggc cgtctcttga aaaatcgtgg tctcaaagta accattcaaa agtttgaccc
    13381 ttatatcaat attgatccgg gaaccatgag tccttaccag cacggggaag tttttgtgac
    13441 agatgacgga gctgagacag atttggactt gggtcactat gaacgtttca tcgatatcaa
    13501 tctcaacaaa tattccaacg tgacaactgg gaaaatttac agtgaagttc ttcgtaaaga
    13561 acgccgtgga gaataccttg gggcaactgt tcaagtcatt cctcatatca cagatgcttt
    13621 gaaagaaaaa atcaagcgtg ccgctctaac gaccgactct gatgtcatta tcacagaggt
    13681 tggtggaaca gtaggagata tcgagtcctt gccattccta gaggctcttc gtcagatgaa
    13741 ggcagatgtg ggtgcggata atgtcatgta tatccataca accttgcttc cttacctcaa
    13801 ggctgctggt gaaatgaaaa ccaaaccaac ccaacactct gtcaaagaat tgcgtggctt
    13861 gggaatccaa ccaaatatgt tggttattcg tacagaagag ccagctggtc aaggaattaa
    13921 aaataaactg gcccagttct gtgatgtggc accagaagcc gttatcgaat cgttggatgt
    13981 tgaacacctt taccaaattc cactgaactt gcaggcacaa gggatggacc aaattgtttg
    14041 tgatcatttg aaattagacg caccagcagc ggatatgaca gaatggtcag ccatggtgga
    14101 caaggtcatg aacctcaaga aacaagttaa gatttccctt gttggtaagt atgtggagtt
    14161 gcaagatgcc tatatctcag tggtcgaagc cttgaaacac tctggctatg tcaatgatgt
    14221 agaagttaaa atcaattggg tcaatgccaa tgatgtgaca gcagagaatg tagcagaact
    14281 cttgtctgat gcggacggga tcatcgtacc aggtggtttt ggtcaacgtg gtacagaagg
    14341 gaaaatccaa gccatccgct atgcgcgtga aaatgatgtt ccaatgttgg gagtctgctt
    14401 gggaatgcag ttgacatgta tcgagtttgc tcgtcacgtt ttaggtcttg aaggtgccaa
    14461 ttctgcagag cttgcaccag aaacaaaata ccctatcatt gatatcatgc gtgatcagat
    14521 tgatattgag gatatgggtg gaacccttcg tttgggactt tatccgtcta agttgaaacg
    14581 tggctctaag gctgctgctg cttatcacaa tcaagaagtg gtgcaacgcc gtcaccgtca
    14641 ccgttatgag tttaataatg ccttccgtga gcagtttgag gcagcaggtt ttgtcttttc
    14701 aggagtttct ccagacaatc gtttggtaga aatcgtggaa attcctgaaa ataaattctt
    14761 tgtagcttgt cagtatcacc ctgaactgtc aagccgtcca aaccgaccag aagaactcta
    14821 cactgccttt gttactgcag cggttgagaa cagcaattag caaaatcaga acctttgaga
    14881 aaaatctcag aggttttttg catacgatga tattgcaata tatctgaggt agggggcctc
    14941 tgtatgtacc tgctaccgtt gaaatcaata gcgactccct cttgccctgt gctagtgaat
    15001 ggatttatca gtatattgaa atgaaataaa atttgaacaa attaattcgg aaagccaaat
    15061 caatttctag caaagtttta ggaactggat tgtatagtga attgaaataa gatgtgaaca
    15121 tctctatcag aaaagtcaaa ttaatttata gaaatatttt agcagtcaag atgtactgtt
    15181 atagattcaa tacattatac ttttttaatt taatccacta tagtaaaatg aaataagaac
    15241 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa atagaggtgt
    15301 actattctag tttcaatata ctatatatct gcagaatact ctttcagttt cattcagcct
    15361 agtcttgctt aggaaaaagt aaaaagccat ccaattatga tggatagctt cttggttctt
    15421 agatttgttc tgcaaaaacc ttttcagcaa ggttcatagc gtggtctgat acacgagtgt
    15481 agtgtgagat gatgtcgata aagttgaccc cagcttgtgt tgaacattcg cctttgttga
    15541 ggcgtttgat gtgggttttt ctgagaacac gttctatctt attgattgct tcatgacgtt
    15601 ctacaagact gcgtgctttt tcaatatcat tgttttccac actatccaga gcatctttga
    15661 taaagtcact agtttggcgg taaacttcct ctaattcttt caaggcggca tcagaaaatt
    15721 caacattttt ccgttgaaga tagtcagtca gattgagtag agcctccgtg tggtctccaa
    15781 tccgttccaa atcacgggag gaatcaagga tattggtaag cacttcactt tctttttggc
    15841 tgagagcttc gcttgaaagg gcaatgagat aacgtgttaa ttgctcatcg atggtgttaa
    15901 ttgcttcttc ggttttatgc cctttttcag caactttttc atccaagtca atgatgtact
    15961 tataggaaag gtcaaaggct ttagcagcgt agtttcctaa gtgcaagagc tctttcttag
    16021 catttcctag agcgatagat ggggcctgtt tgatgaaatg ttcatcaaga tataagggtt
    16081 cgtatttgac aacctcgtcc tctccaggaa taatcttggt tacaaagtaa gccagagctc
    16141 cgataaatgg aaattggaca atggtgttgg taatattaaa ggttccgtga gcaaaggcga
    16201 tggtcatttc cggtgctaga tttagcgtag cttcaaacca atgaatcagg acagtaaaag
    16261 gaactagaaa aataacgcag acgactgttc cgataacgtt gaaggcaaca tgagctcctg
    16321 ctacccgttt agctgcaata ttagccccta aagaggcaat gatggctgta atggttatcc
    16381 cgatattgtc accaaataga actggcaaag ctccctgtag gtcaattaga ttgccggcgt
    16441 agaggttttg taaaatccca atggtagccg aagaagcttg aattagcaag gtcaagccgg
    16501 taccgacaaa gacacccaaa acaggattct tacttagctc aatcatatag tccttaaaga
    16561 cctgtaaatc cttgagtgga gccattgcgc cgctcatgag attgagggca aaaaagatac
    16621 caccgacacc aaagaggatg cgtccgatat tattgactgt ccgatttttt gtaaaaaaga
    16681 gacagacggc accgataaag agcataggta gggcatagtt acctaattta aaaccgatga
    16741 gaaaggatgt gacagttgtc ccaatattag cacccatgac aatcccgata gcctgacgta
    16801 aggttaagag accggcactg accaggccga ctgtgataac tgttacacca gaactagact
    16861 gaattagagc agtcatccca ataccaacca gaactccaaa gaaaggatta ctagtatatt
    16921 tgtcaatgta aaaacgaagg cgatctccag cagcttgttg caaaccgtct cccatggtct
    16981 tgatgctata taagaatagc cccagaccac ctaaaaagtg aaataaaatt tcctgccaat
    17041 taatggacat ttctttttcc tccgaaaaat aatcgcggaa tatcttctat tctattttaa
    17101 aggataaaag taaatctaac aagtgttaat gtcaagtttg taaaagaaaa ttataattga
    17161 taagtgtatt atttttaaga gtttttaacc ttattttaga tttgtgcaaa cagttattgt
    17221 tttttgtcta aaaatgtttt aggataaaaa tgtgattatc atggttctag agtttgataa
    17281 aaaactacag aatataaagc gctttcttga aaacaacaaa atcaatcttt taggaggaga
    17341 aaatgaagaa tccatttttt gaaagacgtt gtcgttacag tattcgtaag ttatcagtag
    17401 gagcctgctc gctgatgatt ggtgctgttt tatttgctgg tccagccttg gctgaagaaa
    17461 ctgcagttcc tgaaaatagc ggagctaata cagagcttgt ttcaggagag agtgagcatt
    17521 cgaccaatga agctgataag cagaatgaag gggaacatgc tagagaaaac aagctagaaa
    17581 aggcagaagg agtagcgata gcatctgaaa ctgcttcgcc agcaagcaat gaagctgcaa
    17641 ctactgaaac tgcagaagca gctagcgcag ctaaaccaga ggaaaaagca agtgaggtgg
    17701 ttgcagaaac accatctgca gaagcaaaac ctaagtctga caaggaaaca gaagcaaagc
    17761 ccgaagcaac taaccaaggg gatgagtcta aaccagcagc agaagctaat aagactgaaa
    17821 aagaagtcca gccagatgtc cctaaaaata cagaaaaaac attaaaacca aaggaaatca
    17881 aatttaattc atgggaagaa ttgttaaaat gggaaccagg tgctcgtgaa gatgatgcta
    17941 ttaaccgcgg atctgttgtc ctcgcttcac gtcggacagg tcatttagtc aatgaaaaag
    18001 ctagcaagga agcaaaagtt caagccttat caaacaccaa ttctaaagca aaagaccatg
    18061 cttctgttgg tggagaagag ttcaaggcct atgcttttga ctattggcaa tatctagatt
    18121 caatggtctt ctgggaaggt ctcgtaccaa ctcctgacgt tattgatgca ggtcaccgta
    18181 acggggttcc tgtatacggt acactcttct tcaactggtc taatagtatt gcagatcaag
    18241 aaagatttgc tgaagctttg aagcaagacg cagatggtag cttcccaatt gcccgtaaat
    18301 tggtagacat ggccaagtat tatggctatg atggctattt catcaaccaa gaaacaactg
    18361 gagatttggt taaacctctt ggagaaaaga tgcgccagtt tatgctctat agcaaggaat
    18421 atgctgctaa ggtaaaccat ccaatcaagt attcttggta cgatgccatg acctataact
    18481 atggacgtta ccatcaagat ggtttgggag aatacaacta ccaattcatg caaccagaag
    18541 gagataaggt tccggcagat aacttctttg ctaactttaa ctgggataag gctaaaaatg
    18601 attacactat tgcaactgcc aactggattg gtcgtaatcc ttatgatgta tttgcaggtt
    18661 tggaattgca acagggtggt tcctacaaga caaaggttaa gtggaatgac attttagacg
    18721 aaaatgggaa attgcgcctt tctcttggtt tatttgcccc agataccatt acaagtttag
    18781 gaaaaactgg tgaagattat cataaaaatg aagatatctt ctttacaggt tatcaaggag
    18841 accctactgg ccaaaaacca ggtgacaaag attggtatgg tattgctaac ctagttgcgg
    18901 accgtacgcc agcggtaggt aatactttta ctacttcttt taatacaggt catggtaaaa
    18961 aatggttcgt agatggtaag gtttctaagg attctgagtg gaattatcgt tcagtatcag
    19021 gtgttcttcc aacatggcgc tggtggcaga cttcaacagg ggaaaaactt cgtgcagaat
    19081 atgattttac agatgcctat aatggcggaa attcccttaa attctctggt gatgtagccg
    19141 gtaagacaga tcaggatgtg agactttatt ctactaagtt agaagtaact gagaagacca
    19201 aacttcgtgt tgcccacaag ggaggaaaag gttctaaagt ttatatggca ttctctacaa
    19261 ctccagacta caaattcgat gatgcagatg catggaaaga gctaaccctt tctgacaact
    19321 ggacaaatga agaatttgat ctcagctcac tagcaggtaa aaccatctat gcagtcaaac
    19381 tatttttcga gcatgaaggt gctgtaaaag attatcagtt caacctcgga caattaacta
    19441 tctcggacaa tcaccaagag ccacaatcgc cgacaagctt ttctgtagtg aaacaatctc
    19501 ttaaaaatgc ccaagaagcg gaagcagttg tgcaatttaa aggcaacaag gatgcagatt
    19561 tctatgaagt ttatgaaaaa gatggagaca gctggaaatt actaactggc tcatcttcta
    19621 caactattta tctaccaaaa gttagccgct cagcaagtgc tcagggtaca actcaagaac
    19681 tgaaggttgt agcagtcggt aaaaatggag ttcgttcaga agctgcaacc acaacctttg
    19741 attggggtat gactgtaaaa gataccagcc taccaaaacc actagctgaa aatatcgttc
    19801 caggtgcaac agttattgat agtactttcc ctaagactga aggtggagaa ggtattgaag
    19861 gtatgttgaa cggtaccatt actagcttgt cagataaatg gtcttcagct cagttgagtg
    19921 gtagtgtgga tattcgtttg accaagccac gtaccgttgt tagatgggtc atggatcatg
    19981 caggagctgg tggtgagtct gttaacgatg gcttgatgaa cactaaagac tttgaccttt
    20041 attataaaga tgcagatggt gagtggaagc tagctaagga agtccgtggt aacaaagcac
    20101 acgtgacaga tatcactctt gataaaccaa tcactgctca agactggcgc ttgaatgttg
    20161 tcacttctga caatggaact ccatggaagg ctattcgtat ctataactgg aaaatgtatg
    20221 aaaagcttga tactgagagt gtcaatattc cgatggccaa ggctgcagcc cgttctctag
    20281 gcaataacaa ggtacaagtt ggctttgcag atgtaccggc tggagcaact attaccgttt
    20341 atgataatcc aaattctcaa actccgctcg caaccttgaa gagcgaagtt ggaggagacc
    20401 tagcaagtgc accattggat ttgacaaatc aatctggtct tctttattat cgtacccagt
    20461 tgccaggcaa ggaaattagt aatgtcctag cagtttccgt tccaaaagat gacagaagaa
    20521 tcaagtcagt cagcctagaa acaggaccta agaaaacaag ctacgccgaa ggggaggatt
    20581 tggaccttag aggtggtgtt cttcgagttc agtatgaagg aggaactgag gacgaactca
    20641 ttcgcctaac tcacgcaggt gtatcagtat caggttttga tacgcatcat aagggagaac
    20701 agaatcttac tctccaatat ttgggacaac cagtaaatgc taatttgtca gtgactgtca
    20761 ctggccaaga tgaagcaagt ccgaaaacta ttttgggaat tgaagtaagt caggaaccga
    20821 aaaaagatta cctagttggt gatagcttag acttgtctga aggacgcttt gcagtggctt
    20881 atagcaatga caccatggaa gaacattcct ttactgatga gggagttgaa atttctggtt
    20941 acgatgctca aaagactggt cgtcaaacct tgacgcttcg ttaccaaggt catgaagtca
    21001 actttgatgt tttggtatct ccaaaagcag cattgaacga tgagtacctc aaacaaaaat
    21061 tagcagaggt tgaagctgct aagaacaagg tggtctataa ctttgcttca ccagaagtaa
    21121 aagaagcttt cttgaaagca attgaagcgg ccgaacaagt gttgaaagac catgaaacta
    21181 gcacccaaga tcaagtcaat gaccgactta ataaattgac agaagctcat aaagctctga
    21241 atggtcaaga gaaatttaag gaagaaaaga cagagcttga tcgtttaaca ggtgaggttc
    21301 aagaactctt ggctgccaaa ccaaaccatc cttcaggttc tgccctagct ccgcttcttg
    21361 agaaaaacaa ggccttggtt gaaaaagtag atttgagtcc agaagagctt gcaacagcga
    21421 aacagagtct aaaagatctg gttgctttat tgaaagaaga caagccagca gtcttttctg
    21481 atagtaaaac aggtgttgaa gtacacttct caaataaaga gaagactgtc atcaagggtt
    21541 tgaaagtaga gcgtgttcaa gcaagtgctg aagagaagaa atactttgct ggagaagatg
    21601 ctcatgtctt tgaaatagaa ggtttggatg aaaaaggtca agatgttgat ctctcttacg
    21661 cttctattgt gaaaatccca attgaaaaag ataagaaagt taagaaagta tttttcttac
    21721 ctgaaggcaa agaggcagta gaattggctt ttgaacaaac ggatagtcat gttatcttta
    21781 cagcaccaca ctttactcat tatgcctttg tttatgaatc tgctgaaaaa ccacaacctg
    21841 ctaaaccagc accacaaaac aaagtccttc caaaacctac ttatcaaccg gcttctgatc
    21901 aacaaaaggc tcctaaattg gaagttcaag aggaaaaggt tgcctttcat cgtcaagagc
    21961 atgaaaatgc tgagatgcta gttggggaac aacgagtcat catacaggga cgagatggac
    22021 tgttaagaca tgtctttgaa gttgatgaaa acggtcagcg tcgtcttcgt tcaacagaag
    22081 tcatccaaga agcgattcca gaaattgttg aaattggaac aaaagtaaaa acagtaccag
    22141 cagtagtagc tacacaggaa aaaccagctc aaaatacagc agttaaatca gaagaagcaa
    22201 gcaaacaatt gccaaataca ggaacagctg atgctaatga agccctaata gcagtcttag
    22261 ccagccttgg tcttgctagt ttagccttga ccttgagacg gaaaagagaa gataaagatt
    22321 aaatatcgaa aaatcttgtg aaatctttcc ttatatttcc aaagtgtgat ataatagttt
    22381 cgaataaaat aaataaagga gtttttgtaa catggcaaaa cttactgtta aagacgttga
    22441 cttgaaaggt aaaaaagtcc tcgttcgtgt tgacttcaac gtaccattga aagatggcgt
    22501 aatcactaac gataaccgta tcacagcagc tcttccaact attaagtaca tcatcgaaca
    22561 aggtggacgt gcaattcttt tctctcacct tggacgtgtg aaagaagaag ctgataaagc
    22621 tggcaaatca cttgctcctg tagcagctga cttggcagca aaacttggtc aagatgttgt
    22681 tttcccaggt gtcactcgtg gtgctgaatt ggaagcggca atcaacgctc ttgaagatgg
    22741 acaagttctc ttggttgaaa acactcgtta cgaagatgtt gacggcaaga aagaatctaa
    22801 aaacgatcct gaacttggta aatactgggc atcacttgga gatggtatct tcgtaaacga
    22861 tgcattcggt acagctcacc gtgcacacgc atctaacgtt ggtatctcag caaacgttga
    22921 aaaagcagtt gctggtttcc ttcttgaaaa cgaaattgcc tacatccaag aagcagttga
    22981 aactccagaa cgtccattcg tggctatcct tggtggttca aaagtttcag acaagatcgg
    23041 tgttatcgaa aacttgcttg aaaaagctga taaagtcctt atcggtggtg ggatgactta
    23101 cacattctac aaagcacaag gtatcgaaat cggtaactca cttgtagaag aagacaaatt
    23161 ggatgttgcg aaagctcttc ttgaaaaagc aaatggtaaa ttgatcttgc cagttgactc
    23221 aaaagaagct aacgcatttg ctggttacac tgaagtgcgt gacactgaag gtgaagcagt
    23281 ttctgaaggc ttccttggtc ttgacatcgg tccaaaatct atcgccaaat ttgacgaagc
    23341 tttgactggt gccaaaacag ttgtatggaa cggacctatg ggtgtatttg aaaacccaga
    23401 tttccaagct ggtacaatcg gtgtgatgga cgctatcgtg aaacaaccag gagttaaatc
    23461 aatcatcggt ggtggtgact cagctgccgc agcgattaac cttggccgtg cagacaagtt
    23521 ctcatggatt agtacgggtg gtggagcatc aatggaactt cttgaaggta aggttcttcc
    23581 aggacttgca gccttgacag aaaaataaga ttttataaac aaatcaaaga agagagggat
    23641 gaaagttcct cttttctttt gcttaaaata aaaacgcttc ctctcaacta ttactcataa
    23701 aaatcaccga tttatgataa aatggaaata gaaagttgag attatgagtt attttaaaaa
    23761 atataaattc gataaatccc agttcaaact tggtatgcga acctttaaaa caggtattgc
    23821 tgtttttcta gttctcttga tttttggctt ttttggctgg aaaggtcttc aaattggtgc
    23881 tttgacagcc gtttttagcc tgagggagag ttttgatgag agtgttcatt ttgggacttc
    23941 gcgtattcta ggaaatagta tcggtggact ctatgccttg gtcttcttct tattaaatac
    24001 ttttttccac gaagcctttt gggtgacctt ggtagttgtt ccaatctgca ccatgttaac
    24061 cattatgaca aatgtagcca tgaataacaa agcaggggtt attggtggtg tagcagctat
    24121 gttaatcatt accctatcaa ttccaagtgg tgagacaatt ttgtacgtgt ttgtgcgtgt
    24181 attagaaacg tttatgggag tttttgtcgc aattatcgta aattacgata ttgatcgtat
    24241 tcgtctcttt ttagagaaaa aagaaaaata atgttacatt ttataacatt atcaattgac
    24301 gtttgtcttt ttttagacta taatagacag aaagaaggaa attgtaaatg aaggaaaaag
    24361 aatttcgccg aaatatggct gtttttccta tcggcagtgt tatgaagttg accgatttat
    24421 cggcgcgtca gattcgttat tatgaagatc aagagttgat caagcccgat cgaaacgaag
    24481 gaaatcgtcg catgtattcc ttgaatgaca tggatcgtct gcttgaaatc aaagattata
    24541 tctctgaagg ttataatatc gctgccatta agaaaaaata tgctgaacgt gaagcgaaat
    24601 ccaagaaagc ggttagtcag actgaagtac gtcgtgcact tcacaatgaa ctcctccaac
    24661 aggggcgttt tgcttcagta cagtcacctt ttggtcgcgg ttaggcaacc gcaagtagtc
    24721 atagattaag gagaaaactt atgccaatca cagctgcaga tattcgtcgt gaagtcaagg
    24781 aaaaaaatgt tacctttatt cgtcttatgt tctcagatat tttgggaacc atgaaaaacg
    24841 tcgaaattcc tgctacagat gaacagttag ataaggtctt gtcgaacaag gttatgtttg
    24901 atggatcttc tattgaaggt tttgtacgta tcaatgagtc ggatatgtac ttgtacccgg
    24961 acttggatac atggacagtc ttcccttggg gagatgaaaa tggaagtgtt gcaggtctga
    25021 tctgtgatgt ctatacaaca gaaggtgaac catttgcggg tgaccctcgt ggtaatttga
    25081 aacgagctct tcgtcacatg gaagaagttg gattcaaatc cttcaacctt ggtccagagc
    25141 cagaattctt cctatttaag ttggatgaaa atggggaccc aacacttgaa gtgaatgaca
    25201 agggtggcta ctttgatttg gcacctactg accttgcgga caacacacgt cgtgagattg
    25261 tgaatgtctt gaccaaaatg ggatttgaag tagaagcgag tcaccacgag gttgcggttg
    25321 gacagcatga gattgacttt aagtacgatg aagttctccg tgcttgtgat aagattcaaa
    25381 tctttaagct tgttgttaaa accattgctc gcaaacacgg actttacgca acatttatgg
    25441 cgaagccaaa atttggtatt gctggatcag gtatgcactg taatatgtcc ttgtttgatg
    25501 cagaaggaaa taacgccttc tttgatccaa atgatccaaa aggaatgcag ttgtcagaaa
    25561 cagcttacca tttcctaggc ggtttgatca agcatgctta caactatact gccatcatga
    25621 acccaacagt taactcatac aaacgtttgg ttccaggtta tgaagcgcct gtttacattg
    25681 cttgggctgg tcgtaaccgt tcgccacttg tgcgcgtacc tgcttcacgt ggtatgggaa
    25741 ctcgtcttga gttgcgttca gtggatccaa tggcgaaccc ttacattgct atggctgttc
    25801 ttttggaagt tggtttgtat ggtattgaaa ataaaatcga agcaccagct cctatcgaag
    25861 aaaatatcta catcatgaca gcagaagagc gcaaggaagc tggtattaca gaccttccat
    25921 caactcttca caacgctttg aaagctttga cagaagatga agtggttaaa gctgctctcg
    25981 gagatcacat ctacactagc ttccttgaag ccaaacgaat cgaatgggca agttatgcaa
    26041 ccttcgtttc acaatgggaa attgataatt atttagacct ttactaatac taatatagaa
    26101 gaaagattgc ctgtgggtaa acagtcacac agcagtctaa gccatcaaat acctataacc
    26161 cttaaaatag cgatttcggt cgctatttat ttttcgaaaa atcctcttga ctcttttgcg
    26221 aattagattt atcatcagac gtgtagaaga aaatcaagga gtcactatgg aaaaattcaa
    26281 tttcaaaaac aatatcgggc aagaaaacaa gttacttcaa atcgaaatct acaagtttac
    26341 taacttttgc aagcttcaaa attacacatc tgtaaatatt ttttcgaaag atatatttga
    26401 agccatagta aattgagact agaatagtac actacatctg ctaaaaattt ctagaaatta
    26461 atttaacttt cctaatcgat ttgtttacat cttatttcaa tctactatat tatctcaata
    26521 aatgatgatg gcgactgttt tgtttgtgct tgtcgatttt tgaatcctga tcgagcggaa
    26581 gaatatttct gccgaggttg tcaaggggaa aatcctgaag atattgaatt ttatgatgaa
    26641 caattacagg cagaaaaggt ggaggctttg aatattcgat tggaagtaaa aaattgaatt
    26701 atctacaatc tcatcaacaa taaacctatt tcaaccccat tatctatagg cgtattttta
    26761 cgccttttta tatacttgaa gcacataaga aacattatgg gaagtttgct gatggaagta
    26821 ctcaagaaat tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggataaaat
    26881 caatttattg gaattttggg caaaataagc cagagaaatc ctttaggtat atagatacgt
    26941 ctagtattga tagaaaaaag aacataatca actacaaaaa tctacaatat ctttcacctg
    27001 aacaagcgcc ttcccgtgcc agaaaattag tttcgcagaa tagtgtctta ttttcaacag
    27061 ttagaccata tctaaaaaat attgctgtag ttagagaact taaagagtat ttgatagcta
    27121 gtacagcatt tattgttttg gatactttac ttaacgaaac atatttgaaa tattatttat
    27181 tatcagataa ttttatcaat cgtgttaata ataaatctac tggaacaagt tatcctgcaa
    27241 tcaatgatta taattttaat ctattattaa tt
//
LOCUS       DAVBED010000027        25943 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBED010000027 DAVBED010000000
VERSION     DAVBED010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.027"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(213..464)
                     /locus_tag="VQ547_001136"
     CDS             complement(213..464)
                     /locus_tag="VQ547_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2542989.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(754..2634)
                     /locus_tag="VQ547_001137"
     CDS             complement(754..2634)
                     /locus_tag="VQ547_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2542990.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2628..3497)
                     /locus_tag="VQ547_001138"
     CDS             complement(2628..3497)
                     /locus_tag="VQ547_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2542991.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3581..6226)
                     /locus_tag="VQ547_001139"
     CDS             complement(3581..6226)
                     /locus_tag="VQ547_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2542992.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6317..7597)
                     /locus_tag="VQ547_001140"
     CDS             complement(6317..7597)
                     /locus_tag="VQ547_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2542993.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7768..9852
                     /locus_tag="VQ547_001141"
     CDS             7768..9852
                     /locus_tag="VQ547_001141"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2542994.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9892..11571)
                     /locus_tag="VQ547_001142"
     CDS             complement(9892..11571)
                     /locus_tag="VQ547_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2542995.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12326..13555
                     /gene="arcA"
                     /locus_tag="VQ547_001143"
     CDS             12326..13555
                     /gene="arcA"
                     /locus_tag="VQ547_001143"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2542996.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13613..14629
                     /gene="argF"
                     /locus_tag="VQ547_001144"
     CDS             13613..14629
                     /gene="argF"
                     /locus_tag="VQ547_001144"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2542997.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14794..15741
                     /gene="arcC"
                     /locus_tag="VQ547_001145"
     CDS             14794..15741
                     /gene="arcC"
                     /locus_tag="VQ547_001145"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2542998.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15950..17461
                     /locus_tag="VQ547_001146"
     CDS             15950..17461
                     /locus_tag="VQ547_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2542999.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17483..18814
                     /locus_tag="VQ547_001147"
     CDS             17483..18814
                     /locus_tag="VQ547_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2543000.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19220..19510)
                     /locus_tag="VQ547_001148"
     CDS             complement(19220..19510)
                     /locus_tag="VQ547_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543001.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19498..19749)
                     /locus_tag="VQ547_001149"
     CDS             complement(19498..19749)
                     /locus_tag="VQ547_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2543002.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20148..21032)
                     /locus_tag="VQ547_001150"
     CDS             complement(20148..21032)
                     /locus_tag="VQ547_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2543003.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21177..22328)
                     /locus_tag="VQ547_001151"
     CDS             complement(21177..22328)
                     /locus_tag="VQ547_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2543004.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22474..24240)
                     /locus_tag="VQ547_001152"
     CDS             complement(22474..24240)
                     /locus_tag="VQ547_001152"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2543005.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24297..>25943)
                     /locus_tag="VQ547_001153"
     CDS             complement(24297..>25943)
                     /locus_tag="VQ547_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2543006.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7351 a         5798 c         5062 g         7732 t
ORIGIN      
        1 tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag ttttgcagga
       61 agtctattga aatactaagc ctacacagac tgatttcaat tttaccattc ttcatagtca
      121 aaaccatcat aatctggata ttgttctggc aacgttccaa ccgaacgtac gagataagct
      181 tcttcgtcct ctgtctcgat ttctctcagc acttagcatt caaaacgcca ttcatcaccg
      241 aagtcgaaaa taaacttaaa tttttgtttg acacttaggc tatccagata gacattttct
      301 atgtaacgtt cttcaacatc gtcactaaca aagctaagaa agtaagaatc tgcatgactc
      361 cactcaacat tatccatgaa aaatgcatga gcatgatcat ttgcaaaatc gaaactccat
      421 aaaatcacat ctgctagttc cgctaacgtt tttgtttttg gaatctatat atgtcggtag
      481 caaccttttt taatttgacg gaaatgatcc aagcttctac agatgctggc ttttcagctt
      541 ctatttcttg ttttactaat tttaactgta gcatttgaaa ccagataatt cttctgtttc
      601 acgcgaaaca ccctgcgcca agcaaggtgt tcttgttttt atactcaatg aaaatcaaag
      661 agcaaactag gaagctagct gcaggctgct caaaacactg ttttgaggtt gtagatggaa
      721 gctgacgtgg tttgaagaga ttttcgaaga gtattaagtc gtataaatcg tcgaagctgt
      781 cgcaatggta tgccactggt tagctgtagt tgctgcgaaa tccttgtctg cgtagaagtc
      841 agtaaatggt aggatttcaa cttccagctc gtcgatgcgg tcaagctggc cagccagata
      901 aacctcgata cggctttctg ctcgtttgat gcgttgcaag agtccgccca tacggatgtc
      961 aactgtatcc aaaccaaaga ccttgttttc tttcagccat tggtgactaa agagggcatg
     1021 gaagtcttca atttggcttc taagttctgg taattcttgt ctggcgattt gttgtaaact
     1081 ttctttatca tccgcttggt aggcctgacg aatgcgtcgt cccacatcta ctttgctact
     1141 taaaatagca ttcaactggg cctgagtttc aaagagataa gcatagtttc cagctttttc
     1201 tttaatgtta gcaagcgtct cagcagcctg agcgaagtgc ggtttgtcct gttcaggtgt
     1261 catgtgttga tcaagaatcg gacaaagaat atcctgataa aaaacatagc ggttgggatt
     1321 gataccgctg agattgcctg gtaggtctgg taagaggttg gcaaggtcaa tctgcataaa
     1381 atcctcaacc gttagaccag tattggtctt gaagtgcgca gacaaaccat ctaggtcatt
     1441 gcgatagctg agttctgccc agatttgcaa gcttggtagg atagagaact gggcagtttc
     1501 accaccattg tctccccaac ccgttacgat gacttcttta atctgattgg cacggcaggc
     1561 tttattagcc tcgatagcca ctagacggct aaaatggttg tgaggtgtaa agccaatcca
     1621 cttccaagct ccccctgcaa atgcaaggtc atggctaatc ttgtgatgat tgcggaaatt
     1681 acggttgtat ttttcctcgc tatcctgata ataatcccag taaaccagag tcacacggtc
     1741 tttgagacgg tctaggtaga cacgagtttc ctctggaatt tccacatcac ggtcgtactg
     1801 gccatccgct gacatgagtt tgaagaacat atcactccac atctggcagt ggaaaccata
     1861 tttgtcagca atatccagca cgcgctccaa gtgttggcac atgaggagac tacgatccac
     1921 aacaccgttc aaaatcaggt agcgtcccaa accaaccaag tgggcttcgt ccatcccgat
     1981 attgaccttg cgagtcttca gtttagacaa cgtggcaaac atgccatcaa tcaggtcata
     2041 aaccttttct tcgccaatga gaagaatgtc ctctacatca cggagctcct gcacttcctt
     2101 gacaccccat ttgacaaagg ccgacaagtg ggccaaggtc tggatgcatg gtacaaaggt
     2161 catgtcaaac tgttgagcat aggcttcgat ttcctgcaac tcctctgctg aataagctcc
     2221 acggaaatag ccaaagtaag gctgcccttc aatctggtaa gtgtcttcca tgtaaagttc
     2281 aaaggttgag tagcccatga gagccaagac ctcaatcatc tgcttggcag aagccacatt
     2341 cagcaccgca tttcgagaac agtcaaccat gtaagccaaa tcttcgtaag ctgcttgttc
     2401 ctcaatctct actttatcag cttctgctag aactgttacc aacaaggata aggcacgata
     2461 aagttggtga ggtttgcggt aggtcaattg atagtgacct tcctcaccct ggatagagat
     2521 agaggcttgg tcagactgag tgacagccac ttccacatct ggtagagaaa tatgaccttt
     2581 taaaacctca atagcttgcg tttgtttggg actaagtcct gtaaatctta ccattgcttt
     2641 tcctcctgta gccagttgac aagagcaccg tagagattgg catctgcgtg ataggtgcag
     2701 gcctggataa ctggtgcgac cgtgtattct tcgtaggtat cgacaaagtt atcaacagcc
     2761 ttcttgacat cttggataaa atctggattt tgactgatag agccacccag actgatgaca
     2821 tctggatcga tcagatactg gatattgagc aagccttgcg ccagattgcg gttcatgcgc
     2881 tcaatggctt cttgacaaag gatattacca gctgcggcct cttggtaaat cttgcgaccg
     2941 tcccaatcag tatgaccaga tttttcaatc acgtatcgta ccatattccc agttgatgct
     3001 agttgcgacc agttattaag tttttcagca ggggcaaggg ttgtcatgta gccaaattct
     3061 ccacccaagc cgtggcgacc tcgatgaagt ctaccattga taatcatggc tccgccaatc
     3121 cctgtcccaa tcacgacaca ggctgcattt tcaagatctg gatgagctag tagttcactg
     3181 agtccaacgc agttggcatc attttctaaa tggacaggta gctgataaga gctaagcgcc
     3241 tcataccaag aaaagccatg gatgtagggc accgcactga agccatcaat cacacctgtc
     3301 tcttgattga ctgcacctgg aacgctcata gcaatcccac tgtaatcctg ttctgacaag
     3361 cgttgatcta gccacgctag taaatcctcc aagttttcag gcgttgaaat acttgtctta
     3421 tccagtattt tcccatcagg agtcagactg gcaaacttaa tcccagtccc tccgatatca
     3481 atcgttgcaa tggtcattgt ttttaccata aaaaggggcg aatcagcagt tagttcttac
     3541 tttttcgccc ctcctttctt ttgatgttta ctttttgaaa ttaaatttct tcttttttga
     3601 tgaattctgt acgaatctct tgtggatcca atggtcctga atgaactgga tatggtcgct
     3661 caagtaagtc aagaatggtt tgttgatgtt ctgatatgtg cacattttct tgactcatat
     3721 tatagtaacg gaagacatag ccttcttcat tttccgccac tttaaaggct gttggacaaa
     3781 cttgcggtat gctgagaaca gaatggctca agaggctacc agtcgcaacc acgcttcctt
     3841 cctgtctagc aagctgaagg ctggtaaacg gtgtctgcaa ggctttggca cgacggaaag
     3901 ctgaaaagcg ttcttgggct tggtggcatt caagtgcaaa ctcgacttca aactcacgca
     3961 agcattgtgc ttctggcgtt gggaagtagc cccagtcacc tagctcacct gatgcacgca
     4021 aaatggtcac ggcaatggtg ttatccccaa ggatttcgta ttcattcaat cccttattgg
     4081 atacagtcac ccctttttca tcgtcataca gactgacaaa agcttgttgg tgttgaggat
     4141 tttcaggatt ttcccatgaa gcagctggtt tgtttggtcg tgtcaccacc tcatagatac
     4201 tttcagaatc attgcttgga cgcgtgttat gagtcttgac caagagacgg atacggtgat
     4261 ccttggcagt gttagtaaag cgagtcttga agcggatttg tggattgtca acaaagacaa
     4321 tcaactcagt ttccagagga atgtttgtca attcttctga ccgtccagcc tcacgcttca
     4381 taaactcgat gataccttgt tgctcttctt ctagcttttc atccgcactg acaggcacgg
     4441 tcaattcatg tttgagcaag attttagcat agcgatctgt gttttccaag acctcgtggc
     4501 ccttaagctc tgcaaagatt ggctctgttc cttttggttg gaaatagata tactcgtttc
     4561 cgatgtcccc acggtcttcg aagcggataa agtcttcata ggcttcgtga gttgtcttgt
     4621 catatactgt gatattgtca tccacactca ccgttacgaa tggtgtatca atcactccgt
     4681 tttggtaaat accctcacgg tgttcttgtt ttccttccag caattggaag gttgtccaag
     4741 aaagcggcgc taggtgaact ggaatggtca cgcgcacttg tcgagcaata cgagcttggc
     4801 ggaacttgtc ttttggtaaa tcgtactcaa aattagctcc gaggtcttcg attgtagcct
     4861 ctacaggacg accatccaag tcctccacac ggtaacttgg taagataaga gcagccatct
     4921 ttttgtagcc ttctgttggg tgcaattcct tgaaatcaca agtcgccaca tcaatcactg
     4981 tgctgacagt atcgacctta tcatgcaagc ctgtgttaat gacagtaaag agatagtcac
     5041 tttgagcctt atccgtagca attttaccct tccactcgtt gagcaagtta cttttaacaa
     5101 agtttcctac ttggttgacc ttggcaaaac gcgtttccat ctcgcggtga acttcgtcca
     5161 cgctacagcc acagatacta tcatgtggcg cattctgcaa aagtgttttc caagcatagg
     5221 tcaactggtc cttgtggttg tgtccaccag tgataatagt caagggttct accacttgct
     5281 ctaggaggtt gctattttct tggaaggctt gttttaggta aatgcgggat gaagaagtgt
     5341 tggcaagtgt gtaccagcca tctgtttcct gactggtcaa ctcgcctgta acagttgata
     5401 agtgttcagg aagcgcacct tctacagctt gaacatattc atcaaaagaa ctatgaacaa
     5461 agattacatc cgggaagagt tcatttgcca cacgaatggc ttcgctcaga tttttctgta
     5521 caggctggtg gtcacagccg ttcatcatca accattggtt ggtcgaagcg taggcacgca
     5581 catctgacaa tttttgtttc cagaaggtca aggcctcatc tttgtcaact gggatttcat
     5641 tcccattact gtaccagttg gcaaagagaa tacctaaaac acgactacca tccacaccct
     5701 gccagtacat ttctgaaaac tgggatgtaa accgctcatc ttcaaggact tggttgtcaa
     5761 atccaatcgg cttcacacca cgaccaaagg ctgccacgtg aatacctgat ttttgaagga
     5821 tttgaggagc ttgtcccata tttccaaagg tatctggaaa gtagccaatc tgggttgatt
     5881 taccccattt ggcagcttct tgttgaccaa tcaaggtatt gcggacattg gcttcactgg
     5941 agatcaagta gtcatcctgc aagatgtaaa agggaccaat tttaagtttg ccctcgtcaa
     6001 tgtagcgttg gaccttgtcg cgattttcag ggcgaatttg taagtagtca tcaaggacaa
     6061 tagtttgtcc atccaagtgg aaactcttga actcagggtc attttcaaag agatcaaaga
     6121 gattgtcaaa caattccacc aactgcatac gatggctttc aaaaggcaag taccactcac
     6181 gatcccagtg actatgtgag ataatatgta caacaacatt ttccatgaag taaaacctca
     6241 ttctaaattt aaattttaac gttttaaatg taaacttgtg attctgataa gaatcggttg
     6301 agctaaagcg agccccttag cggatatcca agtaatccaa gaccaactca cagaacatca
     6361 tgttagccca ggagaaccat tcacgagagt agagggtcgg atcatctacg tggaagcttt
     6421 cgtgcatgac acctgtacca ccatcgcagg caaccagctg atccagcaag aattttttct
     6481 ctgccttatc tcttgttgtc aatccttgga tagaaagggc gattggccag atatagcgat
     6541 agaaggtatg agaacttccg agaccgctag cgtattctcc ttggtagaag tatggatttt
     6601 cagagctcag aatggtacgg cgagtggctt gatacacttc atcatcgatc gaacagtagc
     6661 ccagataggg cgcagctagt agacttggta catttggatc atccatgatg ctggcatttc
     6721 ctaggccatc tacttcaaaa gcgtaaatct tttcgccctt gctgttggtg gtgtaagcgt
     6781 agttttcgat tccttcttgg atttcatcct gaagacgctt ggcatcagca ataacactct
     6841 ggctatcagc taggtttaat gctgcgaaga tttcttgcac ataacccaag actactacag
     6901 caaacatatt tgacggaatc aagtaactat actggcaaca gtcatcactc ggacgaaaag
     6961 ctgaccaagt catacctgtc actgcaaagt caggtccaaa gccatcattt accaaggtgt
     7021 cttccttacg gtccgtatct cggacaaaac gataaggaga gttcttgtgg tcttgttcaa
     7081 ctgtccatag atggagaatt tccttagtcg ctgcgacaaa agtttcatca aactgactag
     7141 tctcgccagt ctctttccag aggagataag ccaactgcaa aggatagcaa agcgaatcca
     7201 cctcatactt gcgctcccag atccagccgt taaggtctgt gtggtcagtc tcgtggtgcc
     7261 ctttccagtt ctcctcaatg ttgaaggagt tagcataggg atccttgagt accaaggtca
     7321 tctgacgttt gaccaaacct gcaatggtct gacgcaggag ggcatctctt ttagctacat
     7381 gaaggtaggg tctgagttgg gctgtcgaat ctcgaagcca catggcagga atatccccag
     7441 tcaagacaaa agttgaacca tcttctaaga tttcaaccgt attgtccaag gtatcggtgt
     7501 agcaacgctc aaagacatca acccactctg gatggtcctt ggcccgctct gctacttcat
     7561 ctagccattc tctaacaatt tctttcgaat aaatcatcgt gcaattccct ctttcaaaca
     7621 agtttcatgt tcagtatata gcttttgaga cagaaaatac atacacaaat gatagtcatt
     7681 tttctacaaa atagttatct ttaaaactcc ttttctaaag gccctctttt tctgatataa
     7741 tgtagaaaaa cagctaaagg aaagactatg aaaccactac ttgaaaccat cgatacccgc
     7801 tttggtactg ctagcaagca tgccttctct cggggaaata ccctgccata cacaggcgtg
     7861 ccttttggga tgaattactt tgtgccccag accagtgacc aggatggatc ttggtttttt
     7921 gatccgcatc tgcctatctt tcaggggatt cgattaactc accagcccag tccttggatt
     7981 ggggactact cttggctcct tctgacacct gtcaccagtc aactgggggg agacagcctc
     8041 tttcaccgcc agtcttctta tgatatagat aaagcttgct tccagcctca ctatttgaag
     8101 ctcttttctc tgcgttatca gattgaaacc cagctcacac cgacttgcta tggtgcttct
     8161 attcgtttga atcaaaagca aggcaaagcc ctctccctct atcttcacgc agcagatgaa
     8221 ctgacagtag agcaagtaga taagcggact cttgccctgc gacaagaagg taaaactgaa
     8281 actaacaaaa attcgctaac gatgttcact gccctgcaaa tgaacacgga tattcttgct
     8341 atcagccaag aagctgggga ctggcgaatt gacttagcaa gtagtcaaac cgagatgcaa
     8401 ctagccactt ctttcatctc tccttctcaa gctctaatca atctacctca agaagatttt
     8461 gatagctgta aaacaagtgc ccaagcggat tgggaaaatc tcctccatcg ttttgacatt
     8521 atagagacag gagaggctga ccgaaccttc tttgaccact gcctctacag actcttcctc
     8581 ttcccacaga ctttttatga ggttgatgag tcagggaaag ccatccacat ggatctggct
     8641 actggtactg tcaagcctgg tgtcctcttt agcaacaatg gtttctggga taccttccgc
     8701 accaccttcc ccctctttgc ccttatcata ccggagcact atcaacgctt tttagaaggt
     8761 ttcctcaata gctaccgcga tactggtttc cttccaaaat ggctggctcc agatgaacgg
     8821 ggtatgatgc caggtacact gctagatggc attatcgcag atagcgcctg taaggacatg
     8881 gcccccgacc tagaaggaga actcttccaa gccatgctcg aaacagccag caaagccgac
     8941 cctctcggca tcaatggccg ccacggacta gcccaatacc aagaactagg ttacctctct
     9001 accgaccacc acgaaagtgt tagccatact ctagactatg cctatagtga cttttgtatc
     9061 gccagctgtg ccaaaaaact agagaacata gaaatcgctg aaacctacaa ggctgcttca
     9121 caaaattacc gccagctatt tgacgctgag acaggttaca tgcgagcacg agacaatcaa
     9181 ggaaactttc accctgactt ctctccttat agttgggggc gagactacgc tgaatgctct
     9241 gccattcaag ctactttagg cgttctccac gacatccctg gcttaatcca actgatgggt
     9301 ggaaaagaaa cctttagcaa ctatcttttg aaagcctgtc aagatgctcc cctctttgaa
     9361 acaacaggct atggttacga aattcacgaa atgagcgaga tggctactgc tccttttgga
     9421 caaatagcca tttccaacca gcctagtttc cacattcctt atctcttccg ctacagcgat
     9481 taccctgact acactgccct tcttatcaag acgctccgtc agaaagcttt tcacccaagt
     9541 tgggaagcct atcctggaga tgaagacaat ggtagtctct ctgcttggta catctggtca
     9601 gctctcggat tttatccaac ctgtccagga aaaccaagct atgatctcgg aatccctctc
     9661 tttgaccatc tacgagtcta cctagctaaa gaaaataaat ggctagatat tcatactgag
     9721 caaaaccaca gccattttaa ctttgtcaaa gaatgccgac tggacaaaac actcgtatca
     9781 actattcaac accaagacct cctaaaagct gaacaactaa ctttcaccct cagctggcta
     9841 ccaaatcact aataaccaaa agaacctttg catcgcgcaa aggttcttct tttatgaaac
     9901 ttggacttga agttgatcca caagctgacc atccaccgtt aggttcagat agaaatccaa
     9961 ggttttatct cctgcgaaat acaaggttgg tagcgtcagc cttttttcag tctcaccagc
    10021 ttgaaacgca aggacataaa tctcgtcctg ataggcgaca ccatggacac ctgtccccgg
    10081 ttgaatcgaa atcttagcct ctaaagagga gctactttca ctacgttcaa tcctaaaatg
    10141 aagagtctct ccctttgcca cagctaggct tttttctgca aatgctagtt cctgaacaac
    10201 ttcttttttt gataacccag gagttttata aagggaaatc ttggtcaata cagggataga
    10261 ttgtgcctcg gtaatcatca cgcgcacctt ttgtgcctct actagcggac ctcgcaagag
    10321 gcgcttatga ccaactgtga agcccctgcc aaactcctgc cagacaccat ccacctctac
    10381 ttgcacatga aaagcagcga ttcgttgccc tagcttcaaa tcttctctta actcaattac
    10441 atcaaaagtt ttaggagaac ctaaatcgag ttctaactgg atgggcaagt ctgcatcgct
    10501 tgcccaagag ctggtctcaa ggccgtctgt caaatggcga caatcaaagt ctgcggaaag
    10561 agctggacca gatacctcag ctcccagagc caaatcttct ttatagagct cattgcgata
    10621 ggtcgcaaat tcataaagtc gttcaatatc ctttgcatca aagagcccag cttgattcgg
    10681 cggaatatta agcaagagtg gagttcctcg ccctactgag tgaaagtaga tttcgaccaa
    10741 ctcctcgaga gacttaggat cctgatcctc atggtagaac cagcctggac ggatggaaac
    10801 atctgcctct ccgattgaaa aaatcgtgcc cgagggatcc ccgtgctgaa gatagttcag
    10861 ctctgcttct gttcctagtt tatcaagatt caccttttgc cacagtggat cacctgcata
    10921 ccctcgttca ttgccaatcc agcggatact ggtgccttct gttgaaaaaa tcaagcaatc
    10981 gccctgcagg tcacgaatgg tttcaaacca tttttcaaat tcataattaa ccttttgcgc
    11041 gccctctcct ctggcaccat ccatccaaac ctcagcgaac ttaccagcat tcccatagtt
    11101 aggatttgat aagatttcct tcaactgagc cagataatag gcattgtagt ccgcttctcg
    11161 gtccacatga tagaggggac tatgggcatc ccacggtgac aggtagaccc ccatatccat
    11221 atcaaactct gtggcagctt gggatacttc aaggagcaag tcgccctttc ctctcctcca
    11281 aggactgacc ttaaccgaat aatctgtgtg agctgtcgga taaaggacaa agccatcgtg
    11341 gtgcttgacc accaaaatca actttttgaa gcccgtttcc ttgagcacac gaacccactc
    11401 acgcgcatcc aactgactcg ggttaaagcg ctcaggatcc tcctgtccag tcccccattc
    11461 ttggtcataa aaggtattag gaccgaagtg gataaaagct gctagttcat ctcccagata
    11521 agctagctga gtctgacttg gtaacggtcc atgcggtttg attttcttca tcgttatata
    11581 tctccttctt ttgcaacttc tcttgttcac aaggttatcc acaggttgtg gataataaac
    11641 catgatctaa cagccagctc tttccaactc caactggtag gctcaggatt tttctcctca
    11701 atgttccctc ttcaaacagc tctgtcatat ggttctgcta acacctctca gaatgctact
    11761 ctccataatt attctcaggc ttctttcagg tcattgtgtg aagaccattc actctccaga
    11821 cttttccaca gattgtgaat aagtgattat tctaagctat cacctcgtcg actataacaa
    11881 aaaataaaaa gagggtcaat aagataatta tctcttccta aatactcaga aaagattcta
    11941 taatttgtac aattgaacaa gaaatgcttc tccaaaatct atcttcaaaa gaatgttgca
    12001 tctttttatc ctttcacaca aacatttctc tttatacaga tccaagtgat aaccagatga
    12061 taattggaca ctttttggtc atttgtatat tttttgaaaa attttttaaa aaaattttat
    12121 atccttttta tagaagttta tgcatttgta tctatgtatt ctatcctatg ttatgtataa
    12181 taacataaaa ttgtgctaaa catcataatt tatattattt tccgagaaat tatagccatt
    12241 gacattacct aggaattgcg ttataacata catgtaagcg gtacccaaaa tggtgccaag
    12301 tcaaaatttt taaggaggaa aatacatgtc ttctcatcca attcaggtct tctcagaaat
    12361 tgggaaactg aaaaaagtta tgttgcaccg tccaggcaag gagttagaaa acttgttgcc
    12421 ggactatctt gaaaggcttc tttttgatga tattcctttc ttggaagatg ctcaaaaaga
    12481 acatgatgca tttgcccaag ctcttcgcga tgaaggaatt gaggttctct acctagaaca
    12541 actcgctgct gaatcattga cctctccaga aatccgcgat caatttatcg aggaatactt
    12601 agacgaagcc aacatccgtg atcgtcaaac caaggttgct attcgtgaat tacttcacgg
    12661 catcaaggac aaccaagaat tggttgaaaa aacaatggct gggattcaaa aagttgaatt
    12721 gccagaaatt cctgacgaag ctaaagatct aactgactta gttgaatcag attatccatt
    12781 tgcaattgac ccgatgccaa acctctattt cactcgcgac ccatttgcaa caattggaaa
    12841 cgccgtatcg cttaaccaca tgtttgcaga tactcgtaac cgtgaaacac tctacggtaa
    12901 gtatatcttc aaataccacc caatctatgg cggaaaagtg gatttggtct acaaccgtga
    12961 agaagatacg cgtatcgaag gtggagacga gctaattctt tctaaagacg tccttgcagt
    13021 aggtatctct caacgtacag acgcagcttc tatcgaaaaa cttttggtca acatcttcaa
    13081 gaaaaatgtt ggcttcaaga aagttttggc ctttgaattt gctaacaacc gtaaattcat
    13141 gcacttggat actgtcttca ctatggtaga ctatgacaag ttcactattc acccagaaat
    13201 cgaaggcaac cttcacgttt actcagttac ttacgaaaac gaaaaactta aaattgttga
    13261 agagaaaggt gacttagctg aacttcttgc tcaaaacctt ggtgtagaaa aagttcattt
    13321 gattcgttgc ggtggtggca atatcgtagc agctgcgcgt gaacaatgga acgacggttc
    13381 taacactttg accatcgcac ctggtgtggt agttgtttat gaccgcaata ccgtgaccaa
    13441 taagattttg gaagaatacg ggcttcgctt gattaagatt cgcggaagtg aattggttcg
    13501 gggccgtggt ggacctcgtt gtatgtctat gccatttgaa cgtgaagaag tgtaatcgct
    13561 gttcggtatt cgtcaataga aaatgtaaaa aatagaaaga ggaaataata aaatgacaaa
    13621 ttcagtattc caaggacgca gcttcttagc agaaaaagac tttacccgtg cagagttaga
    13681 ataccttatt ggtctttcag ctcacttgaa agatttgaaa aaacgcaata ttcaacacca
    13741 ctaccttgct ggcaagaata tcgctctcct atttgaaaaa acatctactc gtactcgtgc
    13801 agcctttaca actgcggcta tcgaccttgg tgctcaccca gaatacctcg gagcaaatga
    13861 tattcagttg ggtaaaaaag aatctactga agatactgct aaagtattgg gacgtatgtt
    13921 tgacgggatt gaattccgcg gattcagcca acgtatggtt gaagaattgg cagaattctc
    13981 aggcgttcca gtatggaacg gtctaactga cgaatggcac ccaactcaaa tgctcgctga
    14041 ctacttgact gttcaagaaa acttcggtcg cttggaaggc ttgacattgg tatactgtgg
    14101 tgatggacgt aacaacgttg ccaacagctt gctcgtaaca ggtgctatcc ttggtgtcaa
    14161 tgttcacatc ttctcaccaa aagaactctt cccagaaaaa gaaatcgttg aattggcaga
    14221 aggatttgct aaagaaagtg gcgcacatgt tctcatcact gaagatgctg atgaagcagt
    14281 taaagatgca gacgttcttt acacagacgt ttgggtatca atgggtgaag aagacaaatt
    14341 cgcagaacgt gtagctcttc ttaaacctta ccaagtcaat atggacttag ttaaaaaagc
    14401 aggcaatgaa aacttgatct tcctacactg cttgccagca ttccacgata ctcacactgt
    14461 ttatggtaaa gacgttgctg aaaaatttgg tgtagaagaa atggaagtaa cagacgaagt
    14521 cttccgcagc aagtacgctc gccacttcga tcaagcagaa aaccgtatgc acactatcaa
    14581 agctgttatg gctgctacac ttggtaacct ttatattcct aaagtataat tttagataat
    14641 aaaccgtcta ccaacagcta tgagggctgc gactaatagc tttagtccgg tcctctttta
    14701 tgtaatggta atctattatt tcttataaaa tatgtgaaaa atcattaaat tgaaatctaa
    14761 acgcattcta ttgagtgtga taaaggagaa tttatggcaa atcgtaaaat tgtagtagct
    14821 ttgggaggaa atgcgattct ttcttctgac ccatcagcaa aggctcaaca agaagcttta
    14881 gttgaaacag ctaagcatct tgtaaaattg attaaaaatg gagatgattt gattatcact
    14941 cacggtaatg gacctcaagt tgggaatctc ttgctccaac atttggcatc agactctgaa
    15001 aagaaccctg ccttcccact cgactcactt gtcgctatga cagaaggtag catcggtttc
    15061 tggttgaaaa atgctttgca aaatgctctc ttggatgaag gcatcgaaaa aaatgttgcc
    15121 tctgttgtaa cgcaagttat cgtagataaa aatgatccag cttttgttaa cttgagtaaa
    15181 ccaatcggtc ctttctattc agaagaagaa gcaaaagcag aagccgaaaa gagcggagcg
    15241 actttcaagg aagatgctgg ccgtggctgg cgtaaggtcg ttgcctcacc aaaacctgtt
    15301 gacatcaaag aaattgaaac catccgtact cttttaaata atggtcaagt cgtcgtagct
    15361 gcaggtggtg gcggtattcc cgtcgtcaaa gaaaacaatg gacatttgac tggtgtcgaa
    15421 gcggttattg ataaagactt cgcttcccaa cgtttggcag aattggttga tgcagacctc
    15481 ttcatcgttt tgacaggtgt agattatgta tttgttaact acaacaagcc aaaccaggaa
    15541 aaattggaac atgtgaatgt tgcccagctg gaagaatata tcaaacaaga tcagtttgca
    15601 ccaggtagca tgcttccaaa agtagaagca gctatcgctt ttgtcaatgg tcgtccagaa
    15661 ggaaaagcag ttattacttc ccttgaaaat ctaggcgcct tgattgaatc tgaaagcgga
    15721 acaattattg aaaaaggata agttgtttta ctaataagat gtattctatt tctagtatct
    15781 ttatatcaaa ttagaaatta ttcttgaaaa catgtacaat atttcaaaag atactagttt
    15841 tagactttaa tatggtaaaa caaatataaa tagaaagcgt tttcttgaat gtttatttaa
    15901 gaaagtagtt ggttttttac actttgttag acatcaggag gaaaaacaaa tgagtgaaaa
    15961 agctaaaaaa gggtttaaga tgccttcatc ttacaccgta ttattgataa tcattgctat
    16021 tatggccgtg ctaacttggt ttatccctgc gggggccttt atagaaggta tttacgaggc
    16081 tcagcctcaa aatccacaag ggatttggga tgtcctcatg gcaccgattc gggctatgct
    16141 aggtactcat ccagaggaag gttcgctcat taaagaaacg agcgcagcga ttgatgtagc
    16201 cttcttcatc cttatggttg gtggtttcct tggcattgtc aacaaaactg gtgctcttga
    16261 cgtagggatt gcctctatcg tgaagaagta taagggccgc gaaaaaatgt taattttggt
    16321 attgatgcct ttgtttgccc tcggtggtac aacttatggt atgggtgaag aaacaatggc
    16381 cttctatcca ctccttgtgc cagttatgat ggccgttggt tttgatagcc tgactggtgt
    16441 tgcaattatt ttgctcggtt ctcaaatcgg ctgtttggca tctactctga atccatttgc
    16501 gacaggtatt gcttcagcga ctgcgggagt tggtacaggg gacggtatcg tacttcgtct
    16561 gatcttctgg gttaccttga ctgctcttag tacttggttt gtttaccgtt atgcggataa
    16621 gattcaaaaa gatccgacta agtcactggt ttatagtact cgcaaagaag atttgaaaca
    16681 ctttaacgta gaagaatctt catctgtaga atctacactt agcagcaaac aaaaatcagt
    16741 tctcttctta tttgtgttga cattcatctt gatggtattg agcttcattc catggacaga
    16801 ccttggcgtt accatttttg atgactttaa tacttggttg actggtcttc cagttattgg
    16861 taatattgtc ggttcatcta cttctgcact aggtacttgg tacttcccag aaggcgcaat
    16921 gctctttgcc tttatgggta tcctgattgg tgttatttat ggtcttaaag aagataagat
    16981 tatctcttcc ttcatgaatg gtgctgctga cttgctcagt gttgccttga tcgtagcgat
    17041 tgctcgtggt attcaagtta tcatgaacga cggtatgatt accgatacaa tcctcaactg
    17101 gggtaaagaa ggcttgagcg gtctatcttc acaagtcttt atcgttgtaa cttatatctt
    17161 ctatctacct atgtcattct tgatcccatc ttcatctggt cttgccagcg caactatggg
    17221 tatcatggct ccacttggag aatttgtaaa tgtccgtcct agcttgatta tcactgctta
    17281 ccaatctgct tcaggtgtct tgaacttgat tgcaccaaca tctggtattg tgatgggagc
    17341 tcttgcactt ggacgtatca acattggtac ttggtggaaa ttcatgggca aactcgtagt
    17401 cgctattatt gtagtgacca tcgcccttct tctccttgga accttccttc cattcctata
    17461 aaatagtgag tgaggtgatt ccatgaaaat agatataaca aatcaagtta aagatgaatt
    17521 tcttatatca ttaaaaacct tgatttccta tccttcagta ctcaatgaag gagaaaatgg
    17581 aacacctttt ggacaagcaa tccaagatgt cctagaaaaa actttagaga tttgtcgaga
    17641 cataggtttc actacctatc ttgaccctaa aggttattac ggatatgcag aaatcggtca
    17701 gggagcagag cttctggcca ttctctgtca tttggatgtt gttccatcag gtgatgaagc
    17761 agattggcag acaccgccat ttgaagcaac tatcaaagac ggctgggtat tcggacgtgg
    17821 tgtccaagat gataaaggcc cttcgctcgc agctctctat gcagtaaaaa gcttgctgga
    17881 ccaaggtatt cagttcaaaa agcgcgtacg ctttatcttt ggtaccgatg aggaaaccct
    17941 ctggcgctgc atggcacgct acaataccat cgaagaacag gccagtatgg gctttgcacc
    18001 tgactcatct tttcctctga cctatgctga aaaagggctt ctacaggtca aacttcatgg
    18061 ccctggatcg gatcaactag agcttgaagt aggaggcgcc tttaacgttg taccagacaa
    18121 ggccaactac caaggtcccc tctatgaaca ggtttgtaac ggtctcaaag aagctggtta
    18181 tgattaccaa tccactgaac aaaccgtaac ggttctcgga gtgccaaagc atgctaagga
    18241 tgctagtcaa ggtatcaatg ctgtcatccg actagctacc attcttgctc ctctccaaga
    18301 acaccctgct ctcagttttc ttgcaacaca agcaggtcaa gacggcacag gaagacaaat
    18361 ctttggtgat atagcagatg aaccttctgg tcacctatcc tttaatgtcg caggtctcat
    18421 gatcaatcat gaacgttctg aaatccgtat tgacattcgg actcctgtct tagctgacaa
    18481 ggaagaacta gtagagttgc ttacaagatg tgcacaaaac taccaactcc gctacgaaga
    18541 gtttgactat ctagcgcctc tatacgtcgc agaagacagt aaactcgtta gcacactgat
    18601 gcaaatctac caagaaaaga ctggcgataa cagtcctgct atttcatccg gtggtgccac
    18661 ttttgctcgc accatgccaa attgtgtagc cttcggcgcc ttattcccag gagcgaagca
    18721 gacagaacat caggcaaatg aatgtgccgt tctagaagat ttgtaccgtg ctatggatat
    18781 ttatgccgaa gccgtctatc gacttgcaac ttaatcaggc aactgtttct accaaaaaaa
    18841 atcgaccgat taatgaactg caccccaaaa gttagacaga ataaatctaa cttttggggt
    18901 gttttattat gaaattgagt tatgaagata aagttcagat ctatgaacta agaaagcaag
    18961 gacaaagctt caaacagctt tcaaaaagat ttggtgtgga tgtttctggt ctaaagtcat
    19021 ctgaatcttt gagatgagct ttataaatcg cttttttcag tttttgcact ggtgtttcga
    19081 taaactcaaa ctttttagcc gtggtattgc ctgattttat agtatattga aactagaata
    19141 gtacacctct acttctaaaa catttttaga aatcgatttg actgtcctga acgatttgtc
    19201 ctgttcttat ttcattttac tatatttgag ccacttcgtc tttaacggct ttattcataa
    19261 gctcttgtaa tttttcttta ctatcaatta cttctgattt tccgttgtaa tttattgtaa
    19321 taggttttaa cttacctaat ttctcgacac gctcattaat ttgatctttt ttgaaggctg
    19381 catatgtttt tcctaagatt ttttcgaaaa tatatttatc agatagcggt ttgccttctt
    19441 cttcagcttg gtttttgtat tgatttgaaa cataaggaac aaatccttca tagtaaccta
    19501 atgctcccat aagttcaaaa gcttgttttc taattcaaac cattgcaact cagatttcag
    19561 cttttcagat aaatcctgct catccaaata atgacttgaa attagtgctg aactcgtttc
    19621 tgtatcctgt acaggctgat cacccatacc agcaaaaaat aaactcgttc ctagcaagac
    19681 cgaacaagct cctattgcat atttcctcaa agaaaaacgc tgctttctct caaattgaaa
    19741 ttctttcatc ccatctccca tcattcatta ttactgtata ttttgtatat cagaaatagt
    19801 ttgtattcac aaatctttct agttattccc ttatcattcc taattaaggg aggtaacata
    19861 caataatttt tagttaaatg tatatctatg ttttttgttt ttcttaataa acgcaataca
    19921 aaaagagcct gttgccaagc tctttgtact caatgaaaat caaatagcaa actaggaaac
    19981 tagccacagg ttgctcaaaa caccgttttg aggtagtaga taagactgac gaagtcagct
    20041 caaaacactg ttttgaggtt gcagatagaa ctgacaaagt cagtaacatc tatacggcaa
    20101 ggcgacgctg acgtggtttg aagagatttt cgaagagtat tagtctatta tttcttctca
    20161 gcgcgaaggg ctgacaagat ttgtgttcgg atatcatcca caccatttgg cgtatttggt
    20221 aaaaagatgg tttgatttcc tttagaggca aaggtattca aggtatccaa atactggttg
    20281 gtcaagagga tagacatgat ttgttcttct gtcatgccaa cattggcttc cttgagttcg
    20341 gtgatagact ctgccaatcc atccacaatc gccttacgtt gttgggcaat ccccacacca
    20401 tgaaggcggt ctttttctgc ttctgcttca gctgcagtga caattttaat cttgtcagct
    20461 tccgccaatt cttgtgctgc gacccgctta cgttgcgccg cattgatttc attcatggat
    20521 tgcttaactt ctgcatccgg ttcgactttg gtaatcaagg ttttcacgat aatgtagccg
    20581 taagtggtca tttcttctgc tacttggtgt tgaacttcaa gggcaatctc atcttttttc
    20641 tcaaacaatt catccaaggt taattttgga acagaagagc gaagagcatc ttcgatataa
    20701 gatttaatct gagattctgg acgtatgagt ttatagtaag catctgtcac gctctgctcg
    20761 ttgacacggt actgagtcgc tacattcatc ataacgaaca cattgtcctt ggtcttagtc
    20821 tcaaccacaa tatcactttg caacaagcgc aactgaatcc gtgctgcaat cgagtcaatc
    20881 ccaaaaggca agcgaatatg aataccgcta ttagcaacct tttggtattt cccaaagcgt
    20941 tcaataatcg ccaccgactg ctgacgaacc acataaactg tactcagtgt gactatcacc
    21001 aataggagca cacaaacaat cagaaaaatc atgaaaaata ttgccataat ggaacctcca
    21061 caagtatttt tctagtatta tagcacattt aaagaaggct gtgccgtttt tactgcgatt
    21121 tttcctgaaa tgtcaataat tagaggtgaa ttgtcctatt gtcgtccaat ctcttgctaa
    21181 aataactctt tataaaaggc aatcgtttct tctaaggttg gcataaatgg atttcctggt
    21241 gcgcaggcat caatcaaggc attcttagaa aggtattcaa agtcgaaatc tttttcttca
    21301 ataccaagtt cagtcagttt cttaggaata cctactgtct cagaaagctt ctcaatctca
    21361 acaatcgcat aatcggcaca ttcttgatct gatttacctt ctacatgaag tcccaaggct
    21421 ttggcaacat tgcggaaagc ttctggtaca cgtttagcat tttcatgttc tataactggt
    21481 agcaacatgg cacagcaaac accatgtggc aaattatata ctgcaccgag ttggtgagcc
    21541 attgagtgaa cataaccaag accagcatta ttaaagctca taccaccaag gaagatggca
    21601 ttgaccatac cttcacgcgc ttcaatatca tgtccatttt ctacagcacg aggaagatat
    21661 tccttgataa gctcaatagc accaatagac agtttcttgg ttacatcata agcaccaggt
    21721 gttaccaaag cttcaacagc gtgagtcaga gcatccatac cagtagcagc agtcaaggct
    21781 tgaggtttgg aaagcatgag ttcagggtca ttgacagaaa tcaaggcaag gctattcttg
    21841 tcaaccatta ccatcttaac cttgcgttct tcatcagtaa tcacatagtt aatagtgatt
    21901 tctgctgatg tacctgccgt tgtattgata gccacaaccg gcaagccttt tttagcagac
    21961 ttatgaagcc cttcataatc ctgtggtttt ccaccatttg tagccatgat agaaatacaa
    22021 ctagctgcat cctgtggaga acccccgcca agactgatga taaaatcaca tctatgttct
    22081 tgcaaagcag ctaccccatc tgtgacattt ttacaagtag ggtttggctc tacatcgcta
    22141 aagatgacat attcgattcc ttctgtatcc agtggtttta aagtcttagg taaaatatca
    22201 ctgccttcga tgtacttatc tgtcaccaaa agtgcctttt tatagccaag ttccttgata
    22261 taaggaccca cttcatttac aacacctttt ccaataaggt tgactgccgg aacataaaat
    22321 atagccatat aattttcctc ctgcgcctcc gcgctatcta tttaacatca ttatattact
    22381 ttttgtattc gttttcaatt atttgtgaat tgtttaacaa atctttttaa aaggatagga
    22441 gggacgtaag ttcacctcct atataaacaa gttttattta tgtagtggtc ccaacaactg
    22501 acatgcacga tagtctgctg attctagatc ttctgttcca aataaggacc aatttttagg
    22561 tctaaagata tcttcctcag gtacattatg catattgaca ggaattctca acatagaagc
    22621 caaggtaatc aagtctgctc caatgtgtcc atatgttatg gctccgtgat tagctcccca
    22681 attattcatg acgtcataga cagacttgaa agcacctttt cctgtcaaac gtggagcaaa
    22741 ccaagtagtt ggccatcctg aatctgtacg attatctaaa gtatggtgaa catcttcagg
    22801 aagttcaagt gtgtaacctt ctgcaatttg tagcactgga ccaacccctt ttagaagatt
    22861 gagacgtacc attgttactg gcatatcccc cttcgtcaag aaacgagttg agaatcctcc
    22921 tccacggaag tactcgcggt ttgctggtgg gaagtctgta ttttcaagca tagcctgtac
    22981 ttcactttct tccaactccc agaatggttt cataacaggt ttgccatctc gagtagcttg
    23041 acctgtacca tccaatgtac aagaaccaga gttgattaga tgtaagaagc cagctgcagc
    23101 acaaccctct aaagtatgtc ccgttacacg tttaacagcc tctggactcc aataagtgcg
    23161 cacatcagca aagatttgtg gagtatttgt taatagataa ttaaagagca tagacacacc
    23221 atttagtgaa tcattctctg tcgcaaatac aaatggtttt cgaataccat tccagtcaaa
    23281 ctgagtattg aggaaagttt ccataaaatc tccatttgga aaatggtctg tccactgacg
    23341 ttgaccttgg aaaccagcta ctaaagcatg gtgaccaacc gcttcttcct caaaaccaag
    23401 ttcagcaagc cttgggttac caaccattaa gtcacgtcca atcatgaaca tcttaataac
    23461 aaattcccat tgtttttctt tctcttcttt agaaagaatc aaatcctcac gatttcggtc
    23521 aaccccttct ttgatatgtt cttttaccca aaccatagca cgttcgaact cttctgggtc
    23581 ataaatacca cggtccatac ggcgcgtgaa ctccgtcata tctaccgatt catttcgcat
    23641 tcctaagtat tcttggaaga aatctggatt tacaatagaa ccgccaatcc ccatcgaaac
    23701 actacccatt gataggtaag cagtgtctct catcaagcca gttgcaagag ctgcacgcgc
    23761 ataacgtaaa agtttttctt tgacatcttc tggaatatct gtatcattag cttcctgaac
    23821 atctctacca taaatcccaa aggctggaat ccctttttga gcatgtgaag ctagtacagc
    23881 tgcaagatag acagctcctg ggcgttctgt cccattaaat ccccaaatag catgaggaat
    23941 atctggagac atatccatag tttcactacc ataacaccag catggtgtaa ctgtaattgt
    24001 tgcgcaaaca tttgattttt taaacaactc atgggaagct gcagcctctg gaacacgacc
    24061 aatggtagat ggagaaatca cacattccac aggttcccca tctggatatt tcaatgtgct
    24121 tgaaatcaaa tctgccacac ttttagccat gttcattgtt tgtacttcaa gtgattcgcg
    24181 tacaccttga cgacgaccat caatagtcgg acgaatccca atacgtggat gttgaatcat
    24241 actattttcc tcttattttt ctgtttcttt catactaccg atgataattt ttaaaattac
    24301 ttataagtat aaacctctac ctctgccaaa cttaaaggaa ttcctgcgtt tctcaaagaa
    24361 attctaacct tttttccctt cagccctttt aagtctatgg atagattatt gctttctaaa
    24421 ctgtcaatat gttgtttaaa aacttcatga ttatttgaat catatataat aatatcaaaa
    24481 tttgataatc tctgaatttc agcatctgtt ctattataaa taattaactt ttctaattct
    24541 tcggtttgtg ctaaatctat ctcccaccat gaaggagaat ctcctttggt atgagtcact
    24601 gaatgatgac cataatctcc gtttttattt ccatcaactg ctagacgaga aaaaccattg
    24661 taatccgttg aactctgtcg agtttctttg gttaatgcaa tattagaaag tttcttcgga
    24721 gttctctttg aaccataggc ttcaacttcc gctaaactta acggaatagc tgctgatttt
    24781 aattctattt tgactagctt agcccctaca gaaggtactt ttaaagataa caaaccatca
    24841 actactttat caaaatgtct tctaaaaact tcttctcctg atgaagatag aaaaataaca
    24901 tcaaaattag ataaacgctg aggttcggca tctgttctat tataaatatc aactttagaa
    24961 accgtaaact cttctcccag atcgacctgc caccaagcgt tagaatctgc cttagtatga
    25021 gtcaccgaat gatgtccgta atctccatct ttattaccat caactgctaa agcagctaca
    25081 ccctcataat tggttgaact ttgagtagct accttatttg tagagactac tttatcttct
    25141 gttattttat ctatatcctc ttcagattgc ttaccatctg attctctaaa aacctctact
    25201 tctgctaaac tcaaaggcac tccactcgtt agtaatttaa ctttaatata ccttgctcct
    25261 ttttctttga aatctagact aacagattca cccgacaaat tattaacatg tttcttagca
    25321 acttcgtttc tattattgtc atatagaatc acatcaaaat tagatagacg ttgagtctca
    25381 gcatctgtgc gattataaat tttaacaagc ccaactttat ccattttttt caaatcgact
    25441 tcccaccaag agggattatc tgccctagtg tgtgttaccg aaccagagtt aaaattacca
    25501 tttctgttac catccacagc tctattaggg tctccattgt aatctacaga actttgtgtt
    25561 gttggttttg catatgctat attcaaatta ccatcattaa atttatctgg tgttgggaaa
    25621 gggactgggc ctgtcccttc agtatttata gacatctcta ccattccatt atgattaacc
    25681 gtaatggtat aaacatgggt attctcatcc caattttctg tataagtata atgattttta
    25741 tcgccactta tatttatctg aggtttatga ccagtatgcc cttttaatgt aagtgttgtt
    25801 gtcctaaagt cattatctac aggattgatg gaataatttt tgcttatcca gttcgctaac
    25861 tctaattctt ctttcttcca actttttgat gcatcaaaat ttcctgataa tgcccacata
    25921 gctgtcttat ctgtcctgta att
//
LOCUS       DAVBED010000028        24889 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBED010000028 DAVBED010000000
VERSION     DAVBED010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.028"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            113..1288
                     /gene="mutY"
                     /locus_tag="VQ547_001154"
     CDS             113..1288
                     /gene="mutY"
                     /locus_tag="VQ547_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2543007.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1343..2047
                     /locus_tag="VQ547_001155"
     CDS             1343..2047
                     /locus_tag="VQ547_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543008.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2040..3389
                     /gene="vicK"
                     /locus_tag="VQ547_001156"
     CDS             2040..3389
                     /gene="vicK"
                     /locus_tag="VQ547_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2543009.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3391..4200
                     /locus_tag="VQ547_001157"
     CDS             3391..4200
                     /locus_tag="VQ547_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2543010.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4291..4533
                     /locus_tag="VQ547_001158"
     CDS             4291..4533
                     /locus_tag="VQ547_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2543011.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4535..4789
                     /locus_tag="VQ547_001159"
     CDS             4535..4789
                     /locus_tag="VQ547_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2543012.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4836..5609
                     /locus_tag="VQ547_001160"
     CDS             4836..5609
                     /locus_tag="VQ547_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2543013.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5869..6855)
                     /locus_tag="VQ547_001161"
     CDS             complement(5869..6855)
                     /locus_tag="VQ547_001161"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2543014.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7049..9517
                     /gene="gyrA"
                     /locus_tag="VQ547_001162"
     CDS             7049..9517
                     /gene="gyrA"
                     /locus_tag="VQ547_001162"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2543015.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            9517..10260
                     /gene="srtA"
                     /locus_tag="VQ547_001163"
     CDS             9517..10260
                     /gene="srtA"
                     /locus_tag="VQ547_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2543016.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10504..11301
                     /locus_tag="VQ547_001164"
     CDS             10504..11301
                     /locus_tag="VQ547_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2543017.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11449..11571
                     /locus_tag="VQ547_001165"
     CDS             11449..11571
                     /locus_tag="VQ547_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2543018.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            11593..12633
                     /locus_tag="VQ547_001166"
     CDS             11593..12633
                     /locus_tag="VQ547_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2543019.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            12804..14078
                     /locus_tag="VQ547_001167"
     CDS             12804..14078
                     /locus_tag="VQ547_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2543020.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14088..14966
                     /gene="truB"
                     /locus_tag="VQ547_001168"
     CDS             14088..14966
                     /gene="truB"
                     /locus_tag="VQ547_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2543021.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            15234..15509
                     /locus_tag="VQ547_001169"
     CDS             15234..15509
                     /locus_tag="VQ547_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2543022.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            15617..16255
                     /gene="udk"
                     /locus_tag="VQ547_001170"
     CDS             15617..16255
                     /gene="udk"
                     /locus_tag="VQ547_001170"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2543023.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            16383..17723
                     /locus_tag="VQ547_001171"
     CDS             16383..17723
                     /locus_tag="VQ547_001171"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2543024.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            17701..17913
                     /locus_tag="VQ547_001172"
     CDS             17701..17913
                     /locus_tag="VQ547_001172"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2543025.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            17910..18785
                     /locus_tag="VQ547_001173"
     CDS             17910..18785
                     /locus_tag="VQ547_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2543026.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            18778..19593
                     /locus_tag="VQ547_001174"
     CDS             18778..19593
                     /locus_tag="VQ547_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2543027.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            19586..20017
                     /locus_tag="VQ547_001175"
     CDS             19586..20017
                     /locus_tag="VQ547_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2543028.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            20024..21691
                     /gene="recN"
                     /locus_tag="VQ547_001176"
     CDS             20024..21691
                     /gene="recN"
                     /locus_tag="VQ547_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2543029.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            21693..22421
                     /locus_tag="VQ547_001177"
     CDS             21693..22421
                     /locus_tag="VQ547_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2543030.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            22500..24323
                     /gene="lepA"
                     /locus_tag="VQ547_001178"
     CDS             22500..24323
                     /gene="lepA"
                     /locus_tag="VQ547_001178"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2543031.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(24525..24605)
                     /locus_tag="VQ547_001179"
                     /pseudo
     CDS             complement(24525..24605)
                     /locus_tag="VQ547_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         7542 a         4396 c         5743 g         7208 t
ORIGIN      
        1 gctctttgat tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat
       61 attataaatc agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga
      121 tttgaaagaa tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa
      181 acttctcgct tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc
      241 ttatcacatc tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc
      301 ttactacgaa agattcctgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga
      361 ggagagttta ctgaaagctt gggagggctt gggctattat tctcgagttc gcaatatgca
      421 ggctgcagcc cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg
      481 aatttccagc ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt
      541 taacttgcct gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga
      601 agtcaaccac gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat
      661 cttgattaat ccggatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga
      721 tattgagtct cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc
      781 atatcagaat ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc
      841 tatttatctt aaagcattag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa
      901 tgaaagcgaa aagctcttgg caggtttttg gcatttcccc cttatagaag ttgataactt
      961 ttcgcaagaa gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactttgg
     1021 ccccagtcca gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt
     1081 ttgttttgat acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc
     1141 aggtcaggtg agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga
     1201 agaattcaag aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca
     1261 agccaactta gacagtagcc aagactagct attgtgtctt ctgactattt tttggtataa
     1321 tagtagagaa aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat
     1381 ctcggatatt atcaagttta atatgaccaa ggaaggttac gaagttgtaa ctgcttttaa
     1441 tggtcgtgaa gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt
     1501 gatgcttcca gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt
     1561 gcccattctt atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact
     1621 tggggcagat gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa
     1681 agctcttctg cgtcgttctc aacctatgcc agtagatggt caggaagcag atagtaaacc
     1741 tcaacctatc caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata
     1801 tggcgaagaa ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca
     1861 tacaggtcaa gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt
     1921 tggtgatgtc cgtacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac
     1981 gcccagccga ccagagtata tcttgacgcg ccgtggtgta gggtattaca tgagaaataa
     2041 tgcttgattt actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt
     2101 taggtttcat ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt
     2161 tgaagcaaat caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg
     2221 atatgcaagg tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg
     2281 ttattcgtct cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt
     2341 tttatatgac agatggggtt cttgcgacca accgtcgggg tcagattatc atgattaacg
     2401 atacagccaa gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg
     2461 aattgctcaa gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat
     2521 tgttgctaga ttcccaagat atcaatggcg aatatttgaa ccttcgagtt cgctttgcct
     2581 tgatacgtcg agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg
     2641 agcaggagaa ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac
     2701 ggactcctct gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg
     2761 aaactgtagc accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca
     2821 tggtgacgga tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg
     2881 aactgattaa cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag
     2941 gacaggaaaa ggagaaaaaa tatgagttgg tgagagatta tcccatcaat tctatctgga
     3001 tggaaattga tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta
     3061 agtattcgcc agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga
     3121 ttttatccat ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg
     3181 accgtttcta tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac
     3241 tgtctatcgc taaagaaatt atcaaacaac ataagggctt tatttgggcc aagagtgaat
     3301 acggcaaggg ttcaaccttt accattgtgc tcccttatga taaggatgca gtgaaagaag
     3361 aagtatggga ggatgaagta gaagactaga atgagtgaaa taggctttaa atacagtatt
     3421 ttagcgtcgg gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta
     3481 gtagatgcag gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgtaag
     3541 ccagaagacc tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta
     3601 ggcgttttgg ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct
     3661 atggaaaata gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg
     3721 ggtaaaacca aaacctttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca
     3781 gtcgcaccgc agttctatcg ctttatgaag gatgataaga gttttgtcct cttgacagat
     3841 acaggttatg tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ttatcttatc
     3901 gaggccaacc atgatgtaga gattttgcga tcaggttctt acgcttggcg cctcaaacaa
     3961 cgaatcctat ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg
     4021 acgctaggaa atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc
     4081 aaggaactgg ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga
     4141 gtagacttta aggtttatga tacctcacca gataccgcaa caccattgac agagatatag
     4201 aaagaacgct gagaaggtgt tctttttata ttgactggac acctaaaaag taatacaatg
     4261 gtgttaccat taaaaaaggg agcacaaaag atgactacta ttacattaaa agtttctgaa
     4321 gctgataaaa catttatgaa agcaatggct aagtttgaag gagtttccct ttcggaactt
     4381 attcgcacca aaactcttga agccctagaa gatgaatacg atgctcgtgt ggcagattta
     4441 gcctatcaag agtatttaga agacttggaa aaaggagttg aacccattac ttgggaagaa
     4501 atgatgcatg atttaggctt gaaggatgaa taatttgtat aaattagttc caacaagacg
     4561 ttttatcaag caattgaaaa aattggaccg ttatacgcag aagctaatta caaactattt
     4621 acaaaccaat gttttggaag atccaagacg acacggaaag gctttggttg gtaatcgcgt
     4681 tggtcaatgg cgctatagaa ttggtaatta tcgagttatc gtacaaattg tagatgatga
     4741 attagttgtt gctactctag aagttggtca tcggagagat atttattaaa ttaaagctga
     4801 gtaataacag tatagaaagt aaggagagta aaaatttgaa gaaaaaatgg ttttttgcag
     4861 attattatga cacaacaatt attttacttg ctttaatctc tgttattctg gtattacttg
     4921 gatttgctga gatgattgat ttggacaatc cgccttatag tattattgat ttagtaatct
     4981 ggggtgtttt tgtaattgat tatagttggc gcttttttac gactaaaaga aaatggcgct
     5041 ttattcttga aaatattttt gatttattgg ctattctccc tttaaatgct atttttacag
     5101 tgtttcgatt agggcgtatc tttcgtttag ctaaactaac aaaattactg aaactgactc
     5161 gtttacttag aataattgga cttacaggta aattagaaag aaaaattagt agattcttac
     5221 ggacaaatgg cctgatttat atcttgtatg ttaatatctt tattgttcta gtagggagtt
     5281 cgattttatc cgttgttgaa gaaaaatcct tctcagatag tctttggtgg gctcttgtga
     5341 cagtaactac tgttggatat ggggatattg ttcctgcttc catttttggg aaatggctag
     5401 cagttttact gatgcttgtc ggtattggaa caatagggat gttaacaagt gctttgacga
     5461 acttttttgt aaaggataat ccagatgaac agataaaact tgataaactc aaagatgaat
     5521 tatcgagcca aagaatatta ctagagaaac aatctaaaaa gatagaagaa ctacataaaa
     5581 tgatacaaga tttgattgaa aaaacataat aaaaataaag atgagacaaa gtttgagctg
     5641 aggagaaatc aagtaagttt tgacacaata gaacgcatat tatcaggtat aaaaacttga
     5701 tactatgcgt tttatagaga aataaaataa aatctgaaca aatcaattag gaatttaaag
     5761 cattttataa caacgtttta gagtgatggg gtgctatttc aacttcaacc tactataata
     5821 cagaaaaaaa caactccctg atgattcaag gagttgtcta tagttaaatt agtttttaga
     5881 agcttcttgg aattctggat ttttccatgc ttcgtcaata atagcttgca attctttagc
     5941 agatgcttgc attttttgag tttctgcatc gttcaatgga atgtttactg gacgaacgat
     6001 accatgtgca ccaacaacag ctggttgacc gataaagaca ttctcaactc cgtatagacc
     6061 ttcttggaat actgaaagtg gaagtactgc gttttcatcg tcaaggattg ctttagtgat
     6121 acgagcaagg gctactgcga taccgtagta tgttgcacct tttttgttga tgattgtgta
     6181 ggctgcatca cgaacacctt cgaacaattc aatcaattca gcttcttgaa cattttgagt
     6241 gtctttaagg aattcttcaa ggtttacacc agcgatgtta gcgtgtgacc aaacagcgaa
     6301 ctcagagtca ccgtgttcac ccatgatgta ggcgtgcact gaacgagcat ccacatccaa
     6361 tttttcagca agtgcttgac ggaaacgagc tgagtcaagt gaagtacctg aaccgataac
     6421 gcgttcttta gggaaaccag agaatttcca agttgagtaa gtcaaaacgt caactgggtt
     6481 agcagcaaca aggaagatac ctttgaaacc agattcaaca acttgagtta cgattgattt
     6541 gttgatagca aggtttttac ctacaaggtc aagacgagtt tcacctggtt tttgaggtgc
     6601 acctgcagta atcacaacaa ggtcagcgtc tgcacagtca gagtattgag ctgcatagat
     6661 ttttttaggt gaagtgaagg caagggcgtg actaaggtca agcgcatcac caacagcttt
     6721 ttcatgcaat tgtggaattt cgataattcc aagctcttgt gcaattcctt ggttaacaag
     6781 tgcaaaagcg taagatgaac ctacagcacc atcaccgaca aggataactt ttttgtgttg
     6841 tttagttgaa gtcattgttt taaacatctc cttaatttta ttaggggatt ttccctagac
     6901 aacttcattc tatcactttt aaaaaacttt gtcacgaata tgccttatag ttctcgatgt
     6961 aaacgtttta gtggtttaga ggctgaaata gatgggaatt tatggtataa tgttgttact
     7021 tactaattgt gaaatgaggc atttattaat gcaggataaa aatttagtga atgtcaatct
     7081 gacaaaggag atgaaggcaa gttttatcga ctacgccatg agtgttatcg tagcgcgagc
     7141 tcttcctgat gttcgagatg gcttaaaacc tgttcaccgt cgcattctct acggaatgaa
     7201 tgaattgggt gtgaccccag acaaacccca taaaaaatct gctcgtatta caggggatgt
     7261 catgggtaaa tatcacccac acggggattc ctctatttat gaagccatgg tccgtatggc
     7321 tcaatggtgg agctaccgtt acatgcttgt agatggtcat gggaattttg gttccatgga
     7381 tggagatagt gctgccgctc aacgttatac cgaggcacgt atgagcaaga ttgctctgga
     7441 aatgcttcgt gatatcaaca aaaatacagt tgatttcgtt gataactatg atgccaatga
     7501 acgggaaccc ttggtcttgc cagcgcgttt tccaaacctt ttggttaatg gagcaactgg
     7561 tatcgcggtt gggatggcaa ccaatattcc acctcataat ctgggtgaaa ccattgatgc
     7621 agtgaagttg gtcatggata atcctgaagt gactaccaag gacttgatgg aagtcttgcc
     7681 tggaccagat tttccaactg gtgctcttgt catggggaaa tcaggtatcc ataaggctta
     7741 tgaaacaggt aaaggttcga ttgccctacg ttctcgtaca gagattgaaa cgactaagac
     7801 tggtcgtgag cgcatcgttg taacagaatt tccttacatg gtcaataaaa ccaaggtgca
     7861 tgagcatatt gttcgcttgg ttcaggaaaa acgcattgag ggtatcacag cagtacgtga
     7921 tgagtcaaac cgtgaaggtg ttcgatttgt tattgaagtc aagcgcgacg cctcagccaa
     7981 tgttattctc aataacctct tcaaaatgac ccaaatgcaa accaattttg gtttcaatat
     8041 gctcgctatc caaaatggta taccgaaaat tttgtctctt cgtcagattt tggatgctta
     8101 tatcgagcac caaaaagaag tggttgttcg tcgtacacgt tttgataagg aaaaagcgga
     8161 agcgcgcgct catatcttag aaggtctctt gattgcgcta gaccatatcg acgaagtgat
     8221 tcgtatcatc cgtgctagtg aaacggatgc ggaagctcaa gctgagttga tgagcaagtt
     8281 taagctttct gaacgtcaaa gtcaagctat ccttgatatg cgtcttcgtc gtttgacagg
     8341 tttggaacgc gataagattc aatctgagta tgatgacctc ttggctctga ttgcggattt
     8401 agcagatatt cttgctaagc ctgaacgtgt ttctcaaatt atcaaagacg aattggatga
     8461 agttaaacgt aaattttctg ataagcgccg tacagagttg atgattggac aggtcttgag
     8521 tctcgaggat gaggacttga ttgaagaatc ggatgtcttg attacccttt ctaacagagg
     8581 ctacattaag cgtttggatc aggacgagtt cactgctcaa aaacgtgggg gtcgtggtgt
     8641 ccaaggaacg ggagtgaaag atgatgactt tgttcgtgag ttagtgtcaa ctagcaccca
     8701 tgatcatctg ctcttcttca caaacaaggg acgtgtctat cgtcttaaag gttatgaaat
     8761 tcctgagtat ggtcggactg ccaaagggct accagtagtc aatctcttga aattggatga
     8821 agacgaaagt attcagacgg ttatcaatgt tgagtctgat cgcagtgatg atgcttatct
     8881 cttctttaca acccgtcacg gtattgtgaa gagaaccagt gttaaggagt ttgccaatat
     8941 tcgtcaaaat ggtctcaaag cgctgaattt aaaggatgaa gatgagttaa tcaatgtctt
     9001 gttggcagaa ggagatatgg atattatcat tggtaccaag tttggttatg cagttcgctt
     9061 taatcaatca gccgttcgtg gtatgagtcg tatcgccact ggtgtgaaag gtgttaacct
     9121 tcgtgaagga gacacagttg ttggtgccag cttgattact gatcaagatg aggttcttat
     9181 tatcacagaa aaaggatatg gtaagcgtac agtcgctact gaatacccaa caaaaggtcg
     9241 tggtggtaag ggaatgcaga cagctaaaat taccgaaaaa aatggcttgc tggccggtct
     9301 tatgactgtt caaggggatg aggatttgat gattatcact gatacaggtg tcatgattcg
     9361 aaccaatctt gccaatattt cacaaacagg acgtgcaact atgggagtta aagtaatgcg
     9421 cctggatcaa gatgctcaga tagtgacttt cacaacggtt gcggtggcag aaaaagaaga
     9481 agttgggaca gaaaacgaaa cagaaggtga agaataatgt ctcaaaaaaa taataaaaag
     9541 aaaaacaagc gaaaaaatct gctgacaaat atcctagcag gatttctgat attactgtca
     9601 ctggctttga tttttaatac tcaaattcga aatattttca tagtctggaa taccaataag
     9661 tatcaagtta gccaggtatc aaaagaaaaa ttagaagaaa atcaggatac agaaggcaat
     9721 tttgactttg attctgtcaa agctatctct tcggaagctg ttctaacttc tcaatgggat
     9781 gctcaaaaat taccagttat tgggggaatt gcaattcctg aattggaaat gaatttgccg
     9841 atttttaaag gacttgataa tgttaatctc ttctacggag ctggtacaat gaaacgcgag
     9901 caagtaatgg gagaaggaaa ttatagtcta gctagtcacc atatctttgg tgttgataat
     9961 gctaataaaa tgttattttc tcctttagat aatgctaaaa atggcatgaa gatttatcta
    10021 accgataaaa ataaagttta tacttatgaa atacgtgaag tcaaacgtgt gacaccggat
    10081 cgtgttgatg aagttgatga tagagatggg gtcaatgaaa tcacattagt aacctgtgaa
    10141 gaccttgctg ctacagaacg tattattgtc aaaggtgatt tgaaagaaac aaaagattat
    10201 tcacaaacat ctgatgaaat tctaacagct ttcaatcaac catataaaca attttattaa
    10261 tacaaatcag tgaaatcatg gatttcactg attttttaag attttcataa aaatatagta
    10321 aaatgaaata agaataggac gaatcgttca ggacagtcaa atcgatttct aacaatgttt
    10381 tagaagtaga ggtgtactat tctagtttca atctactata aacttttatg aaatacagaa
    10441 aacgcttcct aaaacctaaa gtttgtgata taattatcaa gaaaaaagat ttaggagttt
    10501 attatggttt cttcagaatt tatctcaaag attgaatttg cttgcaataa gaaagaaagt
    10561 ctttatagtc aaagcaaatt taagtatgcg attcgttcga tgttcgcagg tgcattttta
    10621 accttcagta ctgctgcagg tgcagttggg gctgacttga ttaataaaat tgcaccaggt
    10681 agtggacgct tcctctttcc attcgttttt gcttggggct tggcctacat tgtttttttg
    10741 aatgccgagt tggtcacttc aaacatgatg ttcttgactg ctggtagttt cttaaaaaaa
    10801 atctcttgga gaaaaacagc tgagatttta ctatactgta ccttgttcaa ccttatcgga
    10861 gccttgatag cagggtgggg ctttgctcat tcggcagcct atgcgaatct gacacacgat
    10921 agtttcatct caggtgttgt tgagatgaag ttaggccgct caaatgaatt ggtcttgctt
    10981 gaggcgattt tggcaaatat tttcgtaaat attgcgattc tgtcatttat tttggtcaaa
    11041 gatggtggtg ccaaactttg gcttgtgttg tcagctattt acatgtttgt attcttaaca
    11101 aacgagcaca ttgcggcgaa ctttgcttct ttcgcgattg tgaaattcag tgttgctgcg
    11161 gattcaattg ccaacttcgg tgttggaaat atgcttcgcc actggggtgt gactttcatc
    11221 ggaaacttta tcggaggagg cctcttgatg ggtcttccat atgccttcct caataaaaac
    11281 gaagatactt atgtagatta agaaaatgag cacgattgag tcgtgctttt ttcattttca
    11341 aaataaggta atagctattt cttatatcaa aatatagaaa actgatattt gtaaactata
    11401 actcaaggtg ctacaatatc cttaataaaa tgatatggag gtcaccttat gacttgtgat
    11461 tttaaatttg aaactctaca actacatgct ggtcaagttg tggctccagc tactaagtct
    11521 cgtgcagtgc cgatttatca aacaacatct tttatttttg atgacacgta ggaaggtgct
    11581 gatctgtttg ccttgaggaa accagggaac atttatactc gtatcaccaa tcctacaaca
    11641 gctgcccttg aaggtggtgt tgaagcgcta gcaacagcat caggtatgac tgcagtgact
    11701 tatacgattt tggcgcttgc ccatgctggt gaccatgtag tggctgcttc gactatttac
    11761 ggtggaacct tcaatctttt gaaagaaccc cttcctcgtt atggtatcac aacaaccttt
    11821 gtcgatgttg ataatttgga ggaagtagaa gcagctatca aagacaatac caagcttgtc
    11881 ttgattgaaa ccttgggtaa ctccttgatt aatattccag acctggaaaa actggcagag
    11941 attgctcata aacatcaaat cccacttgtg tcagacaata cttttgcaat accttatttg
    12001 attaacgtct tctctcatgg cgttgacatt gccattcact ctgcgactaa gtttatcggt
    12061 gggcatggta caactattgg aggaataatt gtcgatagtg gtcgttttga ctggacggct
    12121 tcagggaaat tccctcaatt tgttgacgag ggtccaagct gccacaattt gagttatact
    12181 tgtgatgtgg gtgcagcagc ctttattata gctgttcgag ttcaattgct tcgtgataca
    12241 ggtgcagcct tgtcaccatt caatgctttc ctcttgctac aaagacttga aacctcttca
    12301 cttcgtgtgg aacgccatgt acaaaatgct gagacaattg ttgattttct tgtcaaccat
    12361 cctaaggtag aaaaggtaaa ttatccaaaa cttgcagata gtccttatca tgccttggct
    12421 gagaaatact tgccaaaaga tgtcggttca atctttacct tccatgtcaa aggtggcgag
    12481 gaagaagcac gcaaggtcat tgataattta gaaatctttt ctgaccttgc aaacgcggca
    12541 gatgctaaat cgcttgttgt ccatccagca acaaccactc acggtcaatt gtcagaaaaa
    12601 gacctagaag cagcaggtgt cacaccaaac taaattcgtt tgtcaatcgg tcttgaaaat
    12661 gtagaagatt tgattgaaga cttgcgcttg gccttggaaa aaatttaaag taaaagaaga
    12721 taaacagtgg gcttcgactc actgtttttg attttccctc aggcatgata taatggttaa
    12781 agaagtctag aaagaggaac gatatgaacg aaatcaaatg tcccaactgt ggggaagtct
    12841 ttacagtaaa tgagagtcag tatgccgaac tcttgtccca agtgagaacg gcagagtttg
    12901 ataaggaact acacgatagg atgaagcagg aactggcctt ggctgagcaa aaggccatga
    12961 atgagcaaca gactaaactg gctcagaagg atcaagaaat tgcgcaatta cagagtcaga
    13021 tccaaaactt tgatacagaa aaagaattgg ccaagaaaga ggttgaacag acaagccatg
    13081 aggctctctt ggctaaggac aaggaagtac agctcttaga aaatcagttg gctaccttgc
    13141 gtttggagca tgaaaatcaa ctgcaaaaga ccctttctga cctagaaaaa gaacgggatc
    13201 aggttaaaaa ccaactactt ttgcaggaaa aggaaaatga attatctttg gcttctgtta
    13261 agcaaaacta cgaagcccag ctcaaggcag ctagtgaaca agtcgagttt tataaggatt
    13321 ttaaggctca acaatctaca aaagcgattg gggaaagcct agaacagtat gcagagagtg
    13381 agtttaacaa ggttcgtagt ttcgcctttc caaatgctta ctttgagaag gataacaagg
    13441 tctcttcgcg tgggtctaaa ggggacttta tcttccgtga gtgtgatgaa aatggagttg
    13501 aaatcatttc tatcatgttt gagatgaaaa acgaagcaga cggaacagag aagaagcaca
    13561 agaatgcaga tttttacaag gaattggaca aggaccgtcg ggagaagaac tgtgagtatg
    13621 ccgttttggt gaccatgctt gaggccgata atgactactt taacacaggg attgttgacg
    13681 tcagccacga gtatgaaaaa atgtatgttg ttcgtcctca attctttatc cagttgattg
    13741 gtctcttacg taatgcggcg ctaaattccc taaaatacaa gcaggagttg gccttggttc
    13801 gcgagcaaaa tattgacatt acgcattttg aggaagactt ggatgccttt aagctagctt
    13861 ttgctaagaa ctataattca gcttcgacta actttggaaa agctattgat gaaatcgaca
    13921 aggccatcaa acgcatggaa gaggttaaga aattcctgac tacatctgaa aaccaactcc
    13981 gtctagctaa caacaaattg gaagatgtct ctgttaaaaa attgacccgg aaaaatccaa
    14041 caatgaaagc gaagttcgaa gcactgaagg gggagtagaa agcaaaaatg aacggtatta
    14101 tcaacttaaa aaaagaagca ggaatgacct cgcatgatgc ggtttttaaa ctgcgtaaga
    14161 ttttgggaac caagaaaatt ggtcatggtg gaaccttgga tccggatgtg gtgggtgttt
    14221 tgccgattgc ggttggcaag gcgacacgca tggtcgagtt tatgcaggac gagggtaaga
    14281 tctatgaggg ggaaatcatt ctgggctatt ccacgacgac tgaggatgct agtggggaag
    14341 tggtcgcaga aacccctgtt ttgtctccct tggatgaaaa gcttgttgat gaagcgattg
    14401 ctagcttgac tgggcctatt actcagattc cccctatgta ttcggcagtt aaggttaatg
    14461 gtcgcaagct ctatgagtat gcgcgtgctg gtcaggaagt ggagcgtcca gaacgtcagg
    14521 tgaccattta tcaatttgag cgaacaagtc cgatttctta tgatggccaa cttgcccgat
    14581 tcacttttcg tgtaaaatgc agtaaaggga cttacatccg tactttgtca gttgatttgg
    14641 gtgaaaagct tggttatgcg gctcatatgt cccatttgac tcgtactagt gctgctggct
    14701 tacaattaga agacgctctt accttggagg aaattgctga aaaagtagag gctgggcaat
    14761 tagattttct ccatccttta gagattggga caggtgacct tgtcaaagtt ttcctaactc
    14821 cagaagaggc tacagaagtt cgctttggtc gttttattga gctagaccaa acggacaaag
    14881 aactggctgc ctttgaagat gataaattgt tagccattct agaaaaacgg ggcaatctct
    14941 ataagccaag gaaggttttt agctagatcg tttaggaata aaaatcgggt gatagataac
    15001 aattgcttga taaaccccca tactaatagt agaatggttt tgggaattat aatattccaa
    15061 ttgttgcgag ttgtagatac tcaaataatc tatatagaaa tttagaggtg tgaaatgaag
    15121 caacttaaaa ttctttcaga taaatattta gagtccatga caggttctgg tgggaactta
    15181 ggtctaggat ttggtgtgat aattccatga tgtgaaatga gtttcgagaa agggtggagc
    15241 aacttcttca acaaaaagaa ataaatgaaa atagtgagtt gagtcacctg tttcgtcttg
    15301 ctatacaaaa tttagacaga aatgaaaaat accaatcggt catggccaat ttgagtcaag
    15361 ggttgtcact ttacctcatg acgcatcatt accaggcacc taagtctgtc attgattttg
    15421 gtttatggat tgccaaagct cctagccagg aaagagggag actggctttc ttgcagatgc
    15481 ttgctcaaac cctacagggc tttcgttaaa actgtcgaac atcagaggga agactctggt
    15541 gttttttgct gatgagacta taaattttgt aaaaaatgtg atagaataga cgacggataa
    15601 aataacggag gatagcatgc aaaatagacc aatcattatt ggagtgacag gtggttctgg
    15661 tggtggtaaa accagtgttt caagagccat tttatcgcat tttcctgatg aaaagatttc
    15721 catgattgag catgattcat actacaagga tcagtctcat ttgacctttg aagagcgtgt
    15781 caaaaccaac tatgaccatc cttttgcctt tgatacagac ttgatgatcg agcagattaa
    15841 ggaattgttg gcagggcgtc cggtggacat cccgacctac gactatacag agcatacacg
    15901 gagtagcaag acctatcgtc aggagcctca agatgtcttt atcgttgagg gcattttggt
    15961 cttggaggac aagcgtctgc gcgatttgat ggatatcaag atttttgtgg atacggatga
    16021 cgatgtgcgt attattcgtc gtatcaagcg tgatatggag gaacgtggcc gtagccttga
    16081 tagcgttatt aaccagtact taggtgtggt caaaccaatg taccaccagt ttatcgagtc
    16141 aactaagcgt tatgctgata tcgtcattcc tgaaggggtt agcaataccg tggctatcga
    16201 cctgttgacg accaagattg caaagatttt ggaagaagct cgaaacagca aataatcaca
    16261 tgtggaggcc ttgcctcctt tttctatttt tccctcataa tggtacataa atggagattt
    16321 ttaggcatat ttttggtata ataataccca taaaagagca agtaaatgaa tagtaggtgg
    16381 agatggaaaa gtatttatcg gtaacaactt tgaccaaata tctgaaaatg aaattcgata
    16441 aagacccata cttggaacgg gtctatttaa ctggtcaagt ttccaacttt cgtaaacgac
    16501 ctactcacca atatttctcc ctaaaggatg accatgcagt tattcaagcg accatctggt
    16561 ctgggattta tcagaaatta gggtttgacc tggaagaagg aatgaagatc aatgtgattg
    16621 ggcgtgtaca ggtctatgaa ccaagtggta gctactccat catcattgaa aaagctgagc
    16681 ctgatggggt tggggcgctt gcgattcagt ttgaacaact taagaaaaaa ttgacagaag
    16741 aaggcctgtt tcaagaacgc ttcaagcaag ctctacccca attttctaag agaattgggg
    16801 tagtaaccag ccgtagtgga gccgttattc gagatattat cacgaccgtc agcaggcgat
    16861 tcccaggtgt tgacatcctt ctttatccta ccaaggttca aggtgaaggg gctgcggagg
    16921 aaattgctag aaatattgcg cgtgctaatc aacgggacga tttggatttg ctcattattg
    16981 gtcgtggagg tggttctatt gaggatctct gggcctttaa cgaagaaatt gtggtacgag
    17041 ctatttttga atctcgtttg ccagttatct ctagtgtggg gcatgagacg gatgtgacct
    17101 tggcagattt tgtggcagat cgacgcgctg caacgccaac agcggcggct gaactggcaa
    17161 cacctgtgac caagttggat gtattagctc atttgcaaaa tcaggaaaaa cggatggcaa
    17221 cggcagtccg aaatgttcta tctaagaaac aagaggcttt gaaaaaatgc agtcagtctg
    17281 ttatctttag acaacctgag cgcttgtatg acggttattt gcaacgcttg gaccaactgc
    17341 aactgcgttt gaaacaaagt ttgcgaactc ggatttctga taacaaacaa ttagttcaag
    17401 caagaactca tcaattagta caattatcac ctgttaccaa aatccaacgc tatcaagacc
    17461 gtttaggaca gttggacaag ctcttaggta gccaaatggc gttagtttat gacgccaagg
    17521 ttgctgaggc caagcgactt tcggaagctt tgctcatgtt ggatactagc cgaatcgtgg
    17581 cgcgtggtta tgctattgtc aaaaaagaag agtccgttgt agattcggtt gagagtttga
    17641 agaaaaaaga ccaagtaacg cttttgatgc gagatggtca agtagaatta gaggttaaag
    17701 atgtcaaaac aaaagaaatt tgaggaaaat ctagcagaac tggaaaccat tgtccaaagt
    17761 ttggaaaatg gtgaaattgc tctggaagat gcgattactg cctttcaaaa gggcatggtc
    17821 ttgtcaaaag agctccaagc tacgctggac aaggctgaaa agaccttggt caaggtcatg
    17881 caagaagacg gaacagaaag tgattttgaa tgaaaaagca agaaaaatta gctcttgtcg
    17941 agtcggcttt ggaagatttt tatggagacc agcagtttgc ctctagttta cgggagtctg
    18001 ttctctattc tattcatgct ggtggcaagc gtattcggcc ttttctcttg ttagaagttc
    18061 tggaatcctt gcaggttacc atcaaacctg ctcacgcgca ggtagctact gccttggaga
    18121 tgattcatac agggagcttg attcacgatg accttcctgc tatggatgat gacgattatc
    18181 gaagagggcg gttaaccaat cacaagaaat tcggtgaagc tatggccatt ttggctggag
    18241 atgccttatt cttagaccca tatgccttga ttgcgcaggc agatttgcca agtcagatca
    18301 aggtggactt gattgccaac ttatcccttg cttcaggtag tctgggtatg gtggcagggc
    18361 aagttttgga tatggagggc gaacaccagc acttgtctct ggaagaactt cagactattc
    18421 atgccaataa gactgggaag ttactagcct atcccttcca agcggcagct attatagctg
    18481 aattgtcacc tgaaatgcag gtgaagctga aaactgtggg tgaattgatt ggacttgctt
    18541 ttcaagtcag agatgatgta ctggatgtga cagctagttt tgaggaaatc ggcaagacac
    18601 ctcaaaagga tctgcaggca gaaaaatcaa cctatcctgc cttgttgggc ttggaagagt
    18661 ccattgcctt ttgtaaccaa accctggatc aagctaatga aaaattagaa gaaattgccc
    18721 agcagcttcc ctttgaaaca gaatcgattg taagtgtagt agaaagtttg agaatcaatg
    18781 gctaaggaaa gagtggatgt actagcttat aaacaggggt tgtttgaaac gagagagcag
    18841 gccaagcgag gtgtgatggc tggtctagtc gtagcagtcc ttaatggaga acggtttgac
    18901 aagccaggag agaaaattcc agatgacacc gaattaaaac tcaaggggga gaaactcaag
    18961 tatgtcagcc gtggtggttt gaaactggaa aaggccttgc aggtctttga tttgtcggtg
    19021 gatggcgcga ctacgattga tatcggggcc tctactggag gttttaccga tgtcatgcta
    19081 cagaatagtg ccaagttggt ctttgcagtc gatgttggta ccaatcagtt ggcttggaaa
    19141 ttacgccaag acccacgagt tgtcagcatg gagcagttca attttcgcta tgctgaaaag
    19201 actgatttcg agcaggagcc gagctttgcc agtattgatg tgagtttcat ttcccttagt
    19261 ctgattttgc cagccttgca cagtgtcttg gctgatcaag gtcaggtggt agcacttgtc
    19321 aaacctcagt ttgaggcagg acgtgagcag attgggaaaa atggaattat tcgagatgct
    19381 aagattcatc agaatgtcct tgaatctgta acagctatgg cagtagaggc aggtttttca
    19441 gtccttggct tggacttttc tcccatccaa ggtggacatg gaaatattga atttttagcg
    19501 tatttgaaaa aagaaaagtc agcaagcaat cagattcttg ctgagattaa agaagcagta
    19561 gagagggcgc atagtcaatt taaaaatgaa taaaaaagaa agacttgaaa aaattagaag
    19621 attggtgaca gattatcaaa tcggcacgca agaagaaatt gtagaacatt tgaaagaagc
    19681 aggtatcact gccactcagg cgacggtatc ccgagatatc aaagagttag gtattgtcaa
    19741 aattcctttg agagacaaca cctatgtcta cgaattgcca aaatcaatcg taaaaagtct
    19801 gcaactggct gaagacaata tcgaatcggc tgaattgatg gataagatga tcaatctcca
    19861 agttattcca ggaaatacgg cttttgtaaa agctcagtta atcgagactt ttgcagacaa
    19921 gatttttagc tgtttgactg atgatagctc gattttagtc attgccagaa gtggaagtct
    19981 agcagaggaa atctttgaac aagtaaaaaa ttggtaggtc tatatgttac ttgaaatttc
    20041 gataaaaaac tttgccatta ttgaggctat ttccctcaat tttgaaaagg ggatgactgt
    20101 cctgactggt gaaacgggtg cagggaagtc gattatcatt gatgccatga atatgatgtt
    20161 gggagctcgt gcgacgacag atgttattcg tcatggtgca ccaaaggcag agattgaggg
    20221 gcttttctca gttgagaata gtcgtctttt acaggaaatt tttgatgagc aaggtttaga
    20281 attaggtgat gaaattatca tccgtcggga aatcttgcaa aatggtcgta gtatcagccg
    20341 tgtaaatggt cagatggtta atctgtctgt tttgcgaact attgggcaac atcttgtaga
    20401 tattcatggt cagcatgacc atgaggagtt aatgcgtccc caactgcata tccagatgtt
    20461 ggatgaattt ggtgatgccg ctttttggga cttgaaagaa acctatcaaa cgagttttga
    20521 tgcctatcgg aaaatgcgca agcaggttct ggaagtcaag aaaaaccaac aggaacacaa
    20581 ggcacgtatc gaaatgttgg aatttcaaat ggcagagatt gaggcagcaa acttgcaggc
    20641 tggagaagac ttggatctca atcaagagcg agataaactc ctcaaccaca aaaatattgc
    20701 ggatacactg accaatgcct acagtatgtt ggacaatgaa gatttttcaa gtctggccaa
    20761 tgttcgttca gccatgaatg acatggaaag tgtcgaagag tatgaccctg aataccgtga
    20821 aatttcaagc tctctgtctg agacctacta tgttttagaa gacattagca aacgtttgga
    20881 agctatcatt gaggaccttg attttgatgg caatcgcctc atgcaggttg agaatcgttt
    20941 ggacctcctt catactatta ctcgtaagta tggtgggact gttgatgatg ttttgcttta
    21001 ttttgccaag attacggaag aatacaatct cttgacaggc aataatcttt cgtctgagga
    21061 catggaagca gagcttaaga agttggaagt caatcttgtc aatttggcag gtcaacttgc
    21121 ttctgctcgt cataatttgg ctcagcaact cgaagctgag attaaacaag aactgcaaga
    21181 tctttatatg gaaaaagccc agtttcaggt tcgttttagt aagggaaaat tcagtcgtga
    21241 gggaaataaa atggttgagt tttatatttc aaccaaccct ggagaagact ttaaaccctt
    21301 ggttaaggtt gcttctggag gggaattatc tcgtctcatg ttagccatta agtctgcctt
    21361 ttcacgtaaa gaaggcaaga ctagcattgt ctttgatgag gtggatacgg gagtttcagg
    21421 tcgtgttgct caagctattg ctcagaaaat tcataaaatt ggtcagcatg gtcaggtttt
    21481 ggctatctcc catttgccac aagtaattgc gattgcagat tatcaattct ttattgagaa
    21541 gattagtaat gaccattcaa cggtttcgac tgttcgtctc ttgacggtcg aagagcgagt
    21601 ggaggaagtt gccaagatgt tggcaggtga tgatgtgaca gaagcagccc tgacgcaagc
    21661 aagagaattg ttgagaaaca gggagaaata agatgacaga ttattatgta attggagatg
    21721 ttcacggaaa agctgggatg ctggaagacc ttctcaaaac ctgggatggt cagccccagt
    21781 tgctctttct aggtgatttg attgacagag gtgaggatag tcaccgtgtt cttgaaatgg
    21841 tcaaggactt ggtggacaat caaggggcta tctgtttgtc cggaaaccac gagtatatgt
    21901 ttttgacttg gctagatgac ccagaagaaa gttatgacca ttatagtcgc aatggtggag
    21961 atacaaccat taactctatc ctaggtcgtc ccttggatgc accagttgat ggagtagaag
    22021 atgccaagcg ggttgccgct gaagcggcag acttggtcga attcattcgt caaatgccat
    22081 ttgtagtaga gacagacaag tatatctttg ttcacgcagg tattgatttg accttggacg
    22141 actggcatga aacaacagat tataaaaaag tatggcttag aaaaccattc cacggagctg
    22201 aaaatcatac tggaaaaacc attgtcttcg gtcatacacc ggtctatggt ttattacagc
    22261 aagaacgcgg tacatctgag ctttggacta cagaagatgg caagattgga atggatggag
    22321 gagctgttta tggtggtgtc cttcacggga ttgtctttac agaccaagga atgacagaac
    22381 accactttat cgaaaatgac ggctttgtcg ctgaagatta gtactcctag cagggtatgg
    22441 tcttgtcaaa atatcaaaaa caatttataa taaatagata ccctgaaagg aagagaatca
    22501 tgaacttaga agaattgaaa aaacgacagg agaagatccg taacttctct attatcgccc
    22561 atattgacca cggaaaatca actctagcag accgcatttt ggaaaaaaca gagacggttt
    22621 caagtcgtga aatgcaggcc cagcttttgg atagcatgga gctagagcgg gaacgtggaa
    22681 ttactattaa gttgaatgcc atcgagttga attacactgc aaaagatggg gaaacttata
    22741 ttttccactt gattgacaca ccagggcacg ttgactttac ctatgaagtt tcacgttcgc
    22801 tagctgcctg tgagggtgct attttggtgg tcgatgcggc tcaaggaatt gaggctcaaa
    22861 ctcttgccaa cgtttatctg gctttggata atgatttgga aatcatgcct atcattaata
    22921 aaattgacct gccggctgca gatccggagc gcgtgcgtac agagattgaa gatgtgattg
    22981 gtttggatgc cagtgaagca gttttggctt ctgccaaggc tggtattggg attgaagaaa
    23041 tcctcgagca aattgtagaa aaagtaccag caccaacggg tgatgtgacg gcgccactta
    23101 aggccttgat tttcgactct gtttacgatg cttaccgtgg ggttatcctc caagtgcgtg
    23161 tcatggacgg agtggtcaaa cctggtgata agattcagct catgagcaat agtaagacct
    23221 ttgatgtggc cgaagtcggt atttttacac caaaagcggt tggtcgtgat ttccttgcga
    23281 ctggtgatgt tggttacatt gcggcgtcta tcaagacggt tcaggatact cgtgtgggtg
    23341 ataccgttac cttggcaacc aatcctgcgg cagaaccatt acatggttat aagcagatga
    23401 atcctatggt ctttgcgggt ctctacccaa tcgaatcaaa caagtacaat gacctgcgtg
    23461 aagcgcttga aaaattgcaa ctgaatgatg ctagtcttca gtttgaacca gaaacatctc
    23521 aggcacttgg atttggtttc cgttgtggat ttcttggact tctccatatg gatgttatcc
    23581 aggaacgttt agagcgtgag ttcaatattg acctcatcat gacagctccg tctgttattt
    23641 acaaagttaa tttgaccgac ggtgagtcta tggatgtgtc taacccatct gagtttccag
    23701 acccaactaa gattgcgacc attgaagagc cttatgtcaa ggcgcaaatc atggtaccac
    23761 aggagttcgt cggagcagta atggagctag ctcagcgtaa gcgtggggac tttgtgacta
    23821 tggactatat tgatgataac cgtgtcaatg ttatctatca aattcctctt gctgaaattg
    23881 tctttgactt ctttgataaa cttaagtctt cgacacgtgg ttatgcaagc tttgactacg
    23941 aattgtcaga atatcgccca tctaagctgg tgaaaatgga tattcttctc aatggagata
    24001 aggtggatgc cctcagcttt atcgttcaca aggactttgc ctacgaacgt gggaaactca
    24061 tcgttgataa actcaagaaa atcatccctc gccaacaatt tgaagttcca atccaagcgg
    24121 ctattggaca caagattgtc gctcgtactg atatcaaggc ccttcgtaag aacgtacttg
    24181 ctaaatgtta tggtggtgac gtttctcgta agcgtaaact ccttgaaaaa caaaaagctg
    24241 gtaagaaacg catgaaatcc atcggatcag ttgaagttcc gcaagaagcc ttcctcagcg
    24301 tcttgagtat ggatgaagaa taagttatca gaaatgcctt tccttgttca caggaaattt
    24361 ataagaatca atagtaaagc aggcttagat ggtctgcttt tttagttttt atactcttcg
    24421 aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatggttact gacttcgtca
    24481 gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagtttc atctacaacc
    24541 tcaaaactgt gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt
    24601 gagtattaga acagaaaaaa tgcttggagt atttgtttgt gtgtttactt ttatataaca
    24661 aactataaac acaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa gtaattaaca
    24721 acgatttcat atagtgttat acttatagca taaagttaat ggaaagaagg gaaaacctta
    24781 tggtattaga ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg gataatcaag
    24841 aataactctt tgatcaggta gcaagcttgt tggaggaacg agaaattgt
//
LOCUS       DAVBED010000029        24327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBED010000029 DAVBED010000000
VERSION     DAVBED010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.029"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQ547_001180"
     CDS             complement(<1..618)
                     /locus_tag="VQ547_001180"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2543032.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ547_001181"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ547_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2543033.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ547_001182"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ547_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2543034.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ547_001183"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ547_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2543035.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ547_001184"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ547_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2543036.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ547_001185"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ547_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2543037.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ547_001186"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ547_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2543038.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ547_001187"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ547_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2543039.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ547_001188"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ547_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2543040.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ547_001189"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ547_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2543041.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ547_001190"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ547_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2543042.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ547_001191"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ547_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2543043.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ547_001192"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ547_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2543044.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQ547_001193"
     CDS             complement(7151..7357)
                     /locus_tag="VQ547_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2543045.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ547_001194"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ547_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2543046.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ547_001195"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ547_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2543047.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ547_001196"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ547_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2543048.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ547_001197"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ547_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2543049.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ547_001198"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ547_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2543050.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQ547_001199"
     CDS             complement(10042..10338)
                     /locus_tag="VQ547_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2543051.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ547_001200"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ547_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2543052.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ547_001201"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ547_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2543053.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ547_001202"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ547_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2543054.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQ547_001203"
     CDS             complement(12402..13019)
                     /locus_tag="VQ547_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2543055.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ547_001204"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ547_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2543056.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQ547_001205"
     CDS             complement(13599..14105)
                     /locus_tag="VQ547_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543057.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQ547_001206"
     CDS             complement(14149..14289)
                     /locus_tag="VQ547_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543058.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ547_001207"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ547_001207"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2543059.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQ547_001208"
     CDS             complement(16628..18166)
                     /locus_tag="VQ547_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2543060.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQ547_001209"
     CDS             complement(18203..18346)
                     /locus_tag="VQ547_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543061.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ547_001210"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ547_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2543062.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQ547_001211"
     CDS             complement(20102..20659)
                     /locus_tag="VQ547_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2543063.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQ547_001212"
     CDS             complement(20656..21906)
                     /locus_tag="VQ547_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2543064.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQ547_001213"
     CDS             complement(22114..22419)
                     /locus_tag="VQ547_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2543065.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ547_001214"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ547_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2543066.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQ547_001215"
     CDS             complement(22858..23124)
                     /locus_tag="VQ547_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2543067.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQ547_001216"
     CDS             complement(23211..23780)
                     /locus_tag="VQ547_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2543068.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ547_001217"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ547_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2543069.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBED010000030        24201 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBED010000030 DAVBED010000000
VERSION     DAVBED010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.030"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..284
                     /locus_tag="VQ547_001218"
     CDS             <1..284
                     /locus_tag="VQ547_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543070.1"
                     /translation="TSDFFEAWFQKFLLPTLTTPSAIIMDNARFHRMGKLELLCEEFG
                     HKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
     gene            complement(491..2749)
                     /locus_tag="VQ547_001219"
     CDS             complement(491..2749)
                     /locus_tag="VQ547_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2543071.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2978..3208)
                     /locus_tag="VQ547_001220"
     CDS             complement(2978..3208)
                     /locus_tag="VQ547_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2543072.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3398..4081
                     /locus_tag="VQ547_001221"
     CDS             3398..4081
                     /locus_tag="VQ547_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2543073.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4081..4815
                     /locus_tag="VQ547_001222"
     CDS             4081..4815
                     /locus_tag="VQ547_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2543074.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4969..5826
                     /locus_tag="VQ547_001223"
     CDS             4969..5826
                     /locus_tag="VQ547_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2543075.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5968..6840
                     /locus_tag="VQ547_001224"
     CDS             5968..6840
                     /locus_tag="VQ547_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2543076.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7122..7805
                     /gene="rpiA"
                     /locus_tag="VQ547_001225"
     CDS             7122..7805
                     /gene="rpiA"
                     /locus_tag="VQ547_001225"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2543077.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7819..9030
                     /locus_tag="VQ547_001226"
     CDS             7819..9030
                     /locus_tag="VQ547_001226"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2543078.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9032..9574
                     /locus_tag="VQ547_001227"
     CDS             9032..9574
                     /locus_tag="VQ547_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2543079.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9590..10399
                     /locus_tag="VQ547_001228"
     CDS             9590..10399
                     /locus_tag="VQ547_001228"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2543080.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10875..11855
                     /locus_tag="VQ547_001229"
                     /pseudo
     CDS             10875..11855
                     /locus_tag="VQ547_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11880..12392
                     /locus_tag="VQ547_001230"
     CDS             11880..12392
                     /locus_tag="VQ547_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2543081.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13039..13749
                     /gene="deoD"
                     /locus_tag="VQ547_001231"
     CDS             13039..13749
                     /gene="deoD"
                     /locus_tag="VQ547_001231"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2543082.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13772..14296)
                     /locus_tag="VQ547_001232"
     CDS             complement(13772..14296)
                     /locus_tag="VQ547_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2543083.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14349..14585)
                     /locus_tag="VQ547_001233"
     CDS             complement(14349..14585)
                     /locus_tag="VQ547_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2543084.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14653..15573)
                     /locus_tag="VQ547_001234"
     CDS             complement(14653..15573)
                     /locus_tag="VQ547_001234"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2543085.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15763..16167
                     /locus_tag="VQ547_001235"
     CDS             15763..16167
                     /locus_tag="VQ547_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543086.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16383..16964
                     /locus_tag="VQ547_001236"
     CDS             16383..16964
                     /locus_tag="VQ547_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2543087.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16961..18238
                     /locus_tag="VQ547_001237"
     CDS             16961..18238
                     /locus_tag="VQ547_001237"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2543088.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18256..18918
                     /gene="deoC"
                     /locus_tag="VQ547_001238"
     CDS             18256..18918
                     /gene="deoC"
                     /locus_tag="VQ547_001238"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2543089.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18905..19294
                     /locus_tag="VQ547_001239"
     CDS             18905..19294
                     /locus_tag="VQ547_001239"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2543090.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19384..20436
                     /locus_tag="VQ547_001240"
     CDS             19384..20436
                     /locus_tag="VQ547_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2543091.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20580..22115
                     /locus_tag="VQ547_001241"
     CDS             20580..22115
                     /locus_tag="VQ547_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543092.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22108..23166
                     /locus_tag="VQ547_001242"
     CDS             22108..23166
                     /locus_tag="VQ547_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543093.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23169..24125
                     /locus_tag="VQ547_001243"
     CDS             23169..24125
                     /locus_tag="VQ547_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543094.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7031 a         4379 c         5501 g         7290 t
ORIGIN      
        1 tgacgagcga cttttttgaa gcatggtttc agaagtttct cttaccaaca ttaaccacac
       61 catcggctat tattatggat aatgcaagat tccatagaat ggggaagcta gaacttttat
      121 gcgaagagtt tgggcataaa cttttacctc ttcctcccta ctcacctgag tacaatccta
      181 ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgttgca
      241 atacctttta cgaggctctt ttgtcctgct cttgtttcaa ttgactatag cagattgaaa
      301 taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt tttagcaatt
      361 gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg gcaagctgtc
      421 aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttaatttt ctactccttt
      481 tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg gcagatttaa
      541 tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt ggattttcaa
      601 ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga agtgggcgtg
      661 ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg tcagttacat
      721 ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg agctcgacaa
      781 tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca aaacggttca
      841 taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta cgtccttctc
      901 tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt gaggtcatga
      961 taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa cgaccatcgt
     1021 ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact tcatcgagaa
     1081 ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc tcatcatagc
     1141 caacataacc tggaggagcg ccgaccaact tagccacact atgtttttcc atgtattcac
     1201 tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc agttgtttgg
     1261 aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg attgggcggt
     1321 taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta tcgactgcat
     1381 catcttggcc aataacatga gacttgagat cttcggctag atggatgagt tgagattgtt
     1441 ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg tgctcaatag
     1501 ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc atttccttat
     1561 acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct cgtgtagctt
     1621 gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga tccacaaaat
     1681 tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc ttgtcaggca
     1741 agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc gcagcatctg
     1801 tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga atagtgattg
     1861 tttcgtccac cgttggttca tcgactttaa caggctgcat acgacgctcg agggcagcat
     1921 ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc agttctccac
     1981 gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc gcagaaccag
     2041 caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt ttgcgaattt
     2101 cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt ccttgaacta
     2161 agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc acatcgccat
     2221 cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca ggttcaccga
     2281 taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg ataatctcat
     2341 cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt acattaatac
     2401 caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca gatccacgat
     2461 tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt gggggaatag
     2521 gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca ccaaagggat
     2581 cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta ggatctgttt
     2641 tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca ttgagattgg
     2701 tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata catctacctc
     2761 atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct atactctcat
     2821 tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa gttgttacaa
     2881 tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa aaaggatttt
     2941 acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt tcgtaaattt
     3001 ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct acgtcacgaa
     3061 gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca acaacaactc
     3121 cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct tcaaggcggt
     3181 tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta tcgttactat
     3241 tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct aattctgcta
     3301 gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa aacatgttat
     3361 aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt ttttacctaa
     3421 gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta tctgtgttat
     3481 ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa agtttaaacc
     3541 gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga tgatggttca
     3601 aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga ttggaatttt
     3661 aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga atagtggtgc
     3721 ttatgtttcg gagattgttc gtgccggaat caatgcggtt ccaaaaggtc agctagaggc
     3781 ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt tgccacaagc
     3841 agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca aggacagctc
     3901 cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag tttctacaac
     3961 aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga ttatgacctc
     4021 tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag ataagaaata
     4081 atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa gaatgaagta
     4141 ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat cggtccttca
     4201 gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc aaccaagggg
     4261 aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt tgccatgcgt
     4321 gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac tgtgatggaa
     4381 aatattacct tgtcacctat caagactaaa ggtgaaagca gggaagttgc tgagaagaga
     4441 gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta tccacagagt
     4501 ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg ggttggctat ggaaccagat
     4561 gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg tgaggtattg
     4621 gctgttatgc aagacattgc caagtcaggg atgactatgg ttatcgtaac acatgagatg
     4681 ggatttgccc gtgaggtggc agatcgtgtt atctttatgg cagacggtgt ggttgttgaa
     4741 gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa agatttcttg
     4801 agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa gttcaaccag
     4861 agctttttct tatagtttga aactatagga taacctagga aagaagtgtt agagggcact
     4921 agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat gacacagatt
     4981 attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa gactgcaaaa
     5041 ttaaaggagg aaacagctct agtgcctggt ttggtagtga ttttggttgg ggataatcca
     5101 gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg ttaccgtagc
     5161 gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct gattgctaaa
     5221 tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc aaaacatatc
     5281 gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg tttccatccc
     5341 ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac acctgcagga
     5401 attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc ggtcgtaatc
     5461 ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa aaatgcgaca
     5521 gtaaccttga cccactcacg aactcataat cttgccaagg tggctgctaa agcagatatt
     5581 cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa accaggtgcg
     5641 gttgtcattg acgttgggat gaatcgagat gaaaatggga agctctgtgg agatgttgat
     5701 tatgaggcag ttgcaccact tgctagccat atcacgccag tccctggagg tgtcggtcct
     5761 atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac attggataga
     5821 aaataagaga agcattcgat taatagagtg tattttctat agctatatct aaaatggcag
     5881 aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct cctttttatt
     5941 gtataataaa agtgagagga aaaaaggatg aaagtgatta atcaaacctt attagaaaaa
     6001 gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct gctgctgctt
     6061 ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc tgtaaaaagc
     6121 ggtgcaggat tgatgaccgt tggaacggac agggaaaata tcccggctct gcacagccat
     6181 ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga gcaattggag
     6241 aaggcagaag ttatcttgct ggggcctggt ttaggagaca atgcttttgg agaagattta
     6301 gttaaacagg tctttgctgg cttaaaacag aatcagattt tgattgtaga cggaggtgcc
     6361 ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat cctaactcct
     6421 caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa ggaagatgca
     6481 acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa aggcccagct
     6541 actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg tggtccttat
     6601 caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt tgtaggccaa
     6661 ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca ttcagccata
     6721 gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag caggtatctt
     6781 cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa gcaaagataa acttgtttaa
     6841 aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg cgcctgcttt
     6901 aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa agagatgaac
     6961 aaatcaaata cataaaagat aaactcattt ttattcgttt tgtaaaaata aaatgcatat
     7021 ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat aaaaagcggt
     7081 ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat ctgaagaaaa
     7141 tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga cttggaacag
     7201 gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa gaaggattgc
     7261 agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc cttaatatcc
     7321 cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc gcggatgaag
     7381 tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg gaaaaggtgg
     7441 tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg gtcgaaaaac
     7501 taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag gtctttcgtc
     7561 attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggtcaa cgttttgtga
     7621 cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat ccaattgctt
     7681 ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc aaccaaatgg
     7741 tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca aaaaaaggaa
     7801 aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt actggattct
     7861 gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt tccagatgga
     7921 gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc aaacatggct
     7981 aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc agctgaaagc
     8041 aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga tactatgact
     8101 ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt ctggaacgga
     8161 ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt tattcgtgaa
     8221 gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg tcagatggaa
     8281 actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc tgcccacgaa
     8341 gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc gattaccctt
     8401 gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga accaggtaac
     8461 ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc aactgttttg
     8521 gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa cgatatcttt
     8581 aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca tggaattgat
     8641 acactattga agactatggg acttgctgag tttgaaaaag gattctcatt cacaaaccta
     8701 gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg tgattgcttg
     8761 catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa tgaccttctc
     8821 ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca cactcgggaa
     8881 tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat tccagtagga
     8941 cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac tgctatgatt
     9001 ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc tggtgagagg
     9061 tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag aattgacaaa
     9121 cttgggactg gaaaaggttg agagctacat caatagtggc aatattttct ttacttcgat
     9181 agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc attatccatt
     9241 tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg aaaatctacc
     9301 agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg agggtttgga
     9361 tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag tgctttattt
     9421 tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta agactgccta
     9481 tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta atgctaaaac
     9541 ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa tgacattttt
     9601 aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag cccctgagtt
     9661 cggtctaatc cttggatcag gacttggaga attggcagaa gaaatcgaaa atccagttgt
     9721 agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc atgctggtaa
     9781 attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaagggc gtttccattt
     9841 ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga aagttcttgg
     9901 atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc ctggtacctt
     9961 gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg gtgaaaactt
    10021 ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag aataccgtgc
    10081 cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg tctatatcgg
    10141 agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga cactgggagc
    10201 agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact ctggcttgaa
    10261 agttctggga atttcatgta tcactaactt tgcggccggt ttccaagaag aactcaatca
    10321 cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct tgcttaaagc
    10381 gattcttgct gaattgtaag aaaaaagatt taaaaggggg agtgcctctg ttttttcagg
    10441 attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt cttcctgctc
    10501 ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc attgtgaaag
    10561 acaagattct aggatactag cattagcttc ctagccaagc agactagtat gataaggaga
    10621 gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca caatgagatt
    10681 tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga aaattggtca
    10741 acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt tgtagtcggc
    10801 tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat gtaacatctg
    10861 aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa aatgatgctc
    10921 caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg cttccggaag
    10981 caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca taaccagctc
    11041 aagcggatga tatccgcaag gttgttgggg aattagccaa ggatataagt attactaagt
    11101 tgtatatgac aggtcattct cttggatgtt acctagctca gattgcagcg gttgaagctt
    11161 accaaaaata tcctgatttt tataaccatg tattgaggaa agtgacaact ttcagtgctc
    11221 ctaaagtgat tacttccaga actgtttgga atgctaagaa tggtttctgg gatgttggtt
    11281 tggaaagtcg taaattagct gttagtggaa aaattaagca ttatgtggtt gataatgaca
    11341 atgttgtgac tcccttgatt cataataatc gtgatattgt tacatttaca ggtaattcac
    11401 gctttaaaca ccgttctcgt ggctattttg aaagtccaat gaatgatatt cctaacttta
    11461 atattggtaa acaagctacc ttggataaac atggttatcg tgatccgaaa ttggataaag
    11521 tgcgattctt taagaaacag gctctgcctc gatcttctag tcaaccaagc gctgaaccaa
    11581 tggaaaatat tgccttagga aaacaggtta ctcaaagttc gacagctttc ggaggagatg
    11641 ctagaagagc tgtggatggc aaagtcgatg gtaactatgg tcacaattct gtcactcata
    11701 caaacttcca atctaagcct tggtggcaag tagatttggc taaagaagaa accattcgcc
    11761 aaatcaatat ttacaaccga acagacactg cccaggatag attggcaaac tttgatgtca
    11821 ttcttttaga cagttctggt aaagaaattg agtgaaaacg tataatatct cctaaagatg
    11881 tgtcagcaca aattacgatt aaccataaaa aagcgcgcta tgttcggatt gagctagaag
    11941 gctataatgc cctcagtctt gcagaagttg aagttttccg ctttatagct acgaatgctg
    12001 aaacggcgac acaagtttct aagccagttc aaccaatcag tcagactcct gtgaaagata
    12061 aaacattgac aattcaacac agtggagctt acattgcccg ctactccata acttgggaag
    12121 aagttccagt agataaagat ggaaaccaag ttgttcgtag tcattcttgg gaaggaaacg
    12181 gtcgcaacca gactgcgggt tttgtcctca acctcccaat caaagaaaat atgagaaatc
    12241 tgcgagttaa gattgagaaa aagacgggcc tactatggaa tagatggcaa acaatctatg
    12301 aaaacagacc aatttcagct caaccccacc gtaaaattac ccattggggt acgacattga
    12361 attccaaggt gagtgacgat gatgtcttgt aatctgatgg tacaatgaca gttagtttgt
    12421 ctagtttata agaaagtact acctgagctt gaatagaact caggtagctc tctgtgaaag
    12481 aacaaaatta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
    12541 caaagcactg ctttgaggtt gtagataaga ctgacgaagt cagtcacata tataatccaa
    12601 ggcgacgttg acgtggtttg aagagatttt cgaagagtat aaacagaaag gtagagcgcg
    12661 tgttctaatt tgaacacgag tagaaaactt ttctaaaaac aaaaacgaaa ggatgggtaa
    12721 actgtattcg ctgaactgaa tacgggcgac tctcctctaa atcaaaatta agaaaggaat
    12781 tgaccccacc ctaaaagtag tgggaaaaag atagttggtc tagcgagcat cgctcactgc
    12841 gcccaactcc tattttccct tcgctttttg atgggtttgg tatctttctc aatataaaat
    12901 aaagaaaggt agagcgtgtg ttttgatttg aacacgagcg gaaaactcgg aaaatagata
    12961 atctgactga aaaatcagga tttctcgtca ggttcctaat tttcagtcgt tttcttctcg
    13021 ctctttgtat cataaattat gtctatccat attgctgctc agcagggtga aattgctgat
    13081 aaaattcttc ttcctgggga tcctcttcgt gctaagttta ttgcggagaa tttccttgat
    13141 gatgctgttt gttttaacga agtgcgtaac atgtttggtt acactggtac ttacaagggt
    13201 cactgtgtat ctgtcatggg aactgggatg ggaatgccat ctatttcgat ttatgcgcgt
    13261 gagttaatcg tagactacgg tgtgaagaaa ttgattcgtg tgggaactgc aggttctttg
    13321 aatgaagagg ttcatgttcg tgaattagtt ttggcgcagg cggctgcaac caactcaaac
    13381 atcgttcgta atgactggcc acagtacgat tttccacaaa ttgctagctt tgatttgctt
    13441 gataaagcct accatatcgc caaaaaactt ggtatgacta ctcacgttgg gaacgttttg
    13501 tcatctgatg tcttttactc aaattacttt gaaaagaata tcgagcttgg taaatgggga
    13561 gtcaaggctg tggaaatgga agcagcagct ctttactatc ttgctgccca ataccatgtt
    13621 gatgcgctag ctatcatgac catctctgat agcttggtca atccagacga agacacaact
    13681 gcagaagaac gtcaaaatac cttcactgat atgatgaagg ttggtttgga aaccttgatt
    13741 gcagaataat tatagccaaa aaggaagccc tttatgaatt gtaggacttc cttttcttat
    13801 ccagaaattg atctagctct ctctgatttc gaagaatagt gactttatgt gaatattctt
    13861 ggcaaagttt ttggtaattt tctttttgag ttttgctacg cccatcccaa agaatccatc
    13921 tgataaactc ccactcaaag cgttcagggc aatctgccgc catactttct ctgacttttc
    13981 cacggtattt aagataacgc ttaaaggctc taaagagaca ggtcaatggc gaaaaattga
    14041 gaaagatgat ttggtcagct tcttgcattc gttcttggta gtagcaccaa gaataattac
    14101 catcgatgac ccaagcttta tgcttggtga gaaagttttt tatctcggtt aacatccatt
    14161 cgcagtcact gtcttgccaa ccaggttgaa attggagtgt gtccatgtgc agttttggaa
    14221 tggagtagta gttagataac ttttctgcta tagttgactt accagaacca gaatatccga
    14281 taattgcgat tttcattttc tactttttcc tatttggaga caaaaaaaca gcctctatgg
    14341 actgtttctt atttagcaag tttagctgaa agacgagctt tatcgcggct tgctttgttt
    14401 ttgtgaatca aacctttagt ttctgcttta tcgatagctg agctagcagc acggaaaagt
    14461 tcttcagatg ggtttgcttc gaaagctttt atagcagtac gcatagctga tttttgagct
    14521 gagttctttt cgttttgttt aacgttcaat tcagcgcgtt tgatagctga tttaatgttt
    14581 gccaatgttc ttacctccat atttactaac tataccatta tatatgaaaa cttacgtttt
    14641 gacaagggaa aattactttt ttaagtaaat ttcatcgatt tcatggttct tgcttttatg
    14701 aagaatcact tctgcacgat ttctggttgg ttcaatataa ttttgcagat ttgtgagatt
    14761 gatactgatc cagacctgat gggcaaagga ctccacttcc ccaatcggca tctgagtaaa
    14821 acgataatag tagctatcag ggtcgttttg ggctaggctc agcattttca agaaacggtc
    14881 cagataccaa ctttcaatat catccactcc agcatctaca tagatggaaa agtcaaagaa
    14941 gtcagtgata tagagacgat cgttttgtgg attttgaaag acattaattc cctcaacaat
    15001 tacaaaatca gcagctttga cactttgttt cttttcgggt acgatgtcgt aaacttcatg
    15061 agaatagaca ggaatatcta catcttgtcc atttttgatg cggtccaaga agttgagaag
    15121 agcttccata tcatagcttt caggaaatcc tttacgattt aaaatcccct gctcaatcaa
    15181 ggtttgattg ggatagagaa aaccatcagt tgtaaccaac tcaaccgtag catctgtaaa
    15241 cgtacgggac agtaggattt gaagtaggcg actggttgtg gattttccaa cggcaacact
    15301 cccagaaacc ccaataataa aaggttgaga tttactttca cgttggagga aaattccttt
    15361 tgaaaaggct aaatcttcct tagttcgctt gtaaatctga atcagatgag ccaaggggag
    15421 atagatatct gtaacgtctt ggagactgat ttggtcatta aaactcttga tagattccaa
    15481 ttcttcttct gtcaaaggag gtgttgtctt tcgatgtaaa gattgccaag tctggcggct
    15541 gattttttca aaatgtaaaa attcgttggt catttgtttt cccctagata ttttgtctat
    15601 cataccataa aaagctaaaa aaataaagcg gtttcttgaa tgtggtaagt caatggtata
    15661 tagtataagt gatcaattta ttgatgaaat aggagataga ttctactgat ttataagctt
    15721 ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat cttaaaacgt
    15781 tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa aggaaccaat
    15841 gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt gatggaacat
    15901 gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact aaaaaaacga
    15961 tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat tgcgacagag
    16021 ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag tttggaaatc
    16081 ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttaggaat tttgttgata
    16141 ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata gatgataaac
    16201 tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta tttataagtg
    16261 ttgaaagaga ttgaagaaaa tggcttcgtg acttgctttc ttcggtcttt ttcgttttat
    16321 tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt gtcatgagta
    16381 aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg agagtggact
    16441 tgttgggaca aaaaatgact tttttgacag atgcgggtgt ttttagcaag aaaatggttg
    16501 actttggaag tcaactcttg ctcaagtgtc tggatgtcaa ccaaggagag acagtcctag
    16561 atgtaggctg tggttatggt ccattaggtt tgtccttggt caaggtttac ggagttcagg
    16621 cgaccatggt tgatattaac actcgtgcct tggatttagc tcggagaaat gctgaaaaaa
    16681 ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa ggacattttg
    16741 atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat gaaatcattg
    16801 agaaaagtaa agatttcttg gaaactggtg gggatttgac aatcgtcatc cagaaaaaac
    16861 aaggggctcc aagtgctaag tccaagatgg aggatgtgtt tggtaattgt gaaatcctta
    16921 aaaaagacaa aggatactat atccttagaa gtgtgaaaga atgagagcag ttgatttaat
    16981 acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc tggtagaagg
    17041 ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg ctgtttattt
    17101 taaaggaatg acgactcgtg aaatttctga tttaacgatg aatatggtta agactgggca
    17161 agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta ctggtggtgt
    17221 cggcgataag gtaaccttga ttttagctcc tcttgttgct agcttcggtg tgcctgtagc
    17281 aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat tggagtccat
    17341 taggggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc aggatattgg
    17401 agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc tctatgccct
    17461 tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg tgatgagcaa
    17521 gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg agggtgcctt
    17581 catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc ttggtaaggt
    17641 tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg gacgagcgat
    17701 tggaaatcgt ctggaaatac ttgaagcatt ggagattttg caaggtcaag gacgtcagga
    17761 tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa atgttaacaa
    17821 gactgttgaa gaagttcacc aacatcttga gaatggtcaa gcactggcta agtttgagga
    17881 aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa atgtagctca
    17941 tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag ctatggactt
    18001 tggtctttat gccatgaggc tgggggctgg tcgtgcagtt aagtctgatg ccttggacta
    18061 tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg gtgaaattgt
    18121 tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt tccaaaaatg
    18181 tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca tctcctaaat
    18241 ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt aaaacaagat
    18301 gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga ctttgccagt
    18361 gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg cacagatgtt
    18421 aaggtttgca cggtagtagg tttccctttg ggagcaacaa cttcagccgt gaaagcattt
    18481 gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat caatgttgga
    18541 gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt agtggaagca
    18601 agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga ccaagaaaaa
    18661 attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac atctactggt
    18721 ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac agttggatct
    18781 gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct tgcctttgtc
    18841 gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa aggagaattg
    18901 gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac atgcctatgt
    18961 cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa gtgtttacac
    19021 gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga gaacagctat
    19081 ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct atggtcaaac
    19141 tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat tttttgaaca
    19201 agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga cggtcgggga
    19261 attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg agtggcacgg
    19321 tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt aggaggttca
    19381 gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc agttggactt
    19441 gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt gaagacaaaa
    19501 gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca atcagcttgg
    19561 gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg tttcacttac
    19621 ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc tggaagttac
    19681 aacctaatct tcggtgttgg ttttgccctt aataatgcag ttaaagatgc agcaaaagaa
    19741 cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa gaatgttgcg
    19801 agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc agcaaaaaca
    19861 actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat ctctcgtttt
    19921 gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt ccaagttgac
    19981 tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc acaatacgca
    20041 gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt ctttgcagag
    20101 gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat cggtgttgat
    20161 cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc aaactttgtt
    20221 cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa caaggcagaa
    20281 aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa aggggttgac
    20341 ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc aaaagctaaa
    20401 atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat ttcttaggaa
    20461 gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca gtaaagcttg
    20521 ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag gaagagcaca
    20581 tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt ggatttgttg
    20641 ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt ttaggagaaa
    20701 atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa ccaactagtg
    20761 gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa gcagctagct
    20821 tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca gtggctgaaa
    20881 acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct ggagctagca
    20941 aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct gccaaggtag
    21001 cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt tatcgggggg
    21061 ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa attgatgagt
    21121 tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg attacccaca
    21181 aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt gggaaatcaa
    21241 ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg atggtaggac
    21301 gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg gttttgtcta
    21361 tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat ctgtccttgg
    21421 atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt cagtctgaac
    21481 tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag ctaaaaggag
    21541 attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg cacgttccag
    21601 aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat attgcccttc
    21661 aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca aatattactt
    21721 cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa ttagttcctg
    21781 cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa attgatcgag
    21841 atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt gccattgagt
    21901 atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt gttgtcagct
    21961 ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac gatggtaaga
    22021 ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc ttgatggctg
    22081 gtggaaactt gggaaaggag aagagtgatg tctaaaaaat tacaacaaat ttcggttccc
    22141 ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat cttcggttat
    22201 gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct gcgtgggatt
    22261 ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt tgcggttgcc
    22321 agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg ttggattctc
    22381 agtggttggt ttgcgctgtc gcatccagat atgccccgtc ccttgatgat tctagcaacc
    22441 atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat tcttagggcc
    22501 tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt cttgtatgta
    22561 gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga ttcgaccatt
    22621 cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac tggtaactca
    22681 cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg gttcatgctc
    22741 aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca tgcttcagaa
    22801 tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc aggtgccttg
    22861 gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta tgttcaaggt
    22921 tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc caactcacca
    22981 attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc tcctggtatg
    23041 aatgcggcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat tatcttcttt
    23101 gtcagtgttc attaccttat cgaacgcttt gtcaaaccga aaaaacaagt taaaggaggt
    23161 aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg ctgatttact
    23221 cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt ggtgtggtaa
    23281 acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc tttaaccttg
    23341 aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta gcaggattgg
    23401 ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt gcagaccatg
    23461 ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc ttagttaaag
    23521 ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc tttgatttcc
    23581 cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact agtctacttg
    23641 gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag actcaatttg
    23701 gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg ggaatcaacg
    23761 tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga attggcggag
    23821 cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt ggacctggat
    23881 ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct atgctttcta
    23941 gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg ccgttcctac
    24001 aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt cttgtcttag
    24061 cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac atcaaatcaa
    24121 aataagcata caaaaaaacg tcagtccaat gactgaactg ccccccaaaa gttagacaga
    24181 aaaaatctaa cttttggggt g
//
LOCUS       DAVBED010000031        23312 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBED010000031 DAVBED010000000
VERSION     DAVBED010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.031"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQ547_001244"
     CDS             complement(196..654)
                     /locus_tag="VQ547_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2543095.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQ547_001245"
     CDS             complement(651..1091)
                     /locus_tag="VQ547_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543096.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQ547_001246"
     CDS             1675..2541
                     /locus_tag="VQ547_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543097.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQ547_001247"
     CDS             2878..3435
                     /locus_tag="VQ547_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2543098.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQ547_001248"
     CDS             3656..4762
                     /locus_tag="VQ547_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2543099.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQ547_001249"
     CDS             4738..6129
                     /locus_tag="VQ547_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543100.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQ547_001250"
     CDS             6126..7304
                     /locus_tag="VQ547_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2543101.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQ547_001251"
     CDS             7729..7962
                     /locus_tag="VQ547_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2543102.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQ547_001252"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQ547_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2543103.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQ547_001253"
     CDS             complement(10519..10986)
                     /locus_tag="VQ547_001253"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2543104.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQ547_001254"
     CDS             complement(10987..12192)
                     /locus_tag="VQ547_001254"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2543105.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ547_001255"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ547_001255"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2543106.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ547_001256"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ547_001256"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2543107.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ547_001257"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ547_001257"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2543108.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQ547_001258"
     CDS             14941..15504
                     /locus_tag="VQ547_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2543109.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQ547_001259"
     CDS             15501..16178
                     /locus_tag="VQ547_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543110.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQ547_001260"
     CDS             complement(16319..17350)
                     /locus_tag="VQ547_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2543111.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQ547_001261"
     CDS             complement(17605..18288)
                     /locus_tag="VQ547_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2543112.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQ547_001262"
     CDS             complement(18300..19244)
                     /locus_tag="VQ547_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2543113.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ547_001263"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ547_001263"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2543114.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQ547_001264"
     CDS             22200..23261
                     /locus_tag="VQ547_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2543115.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVBED010000032        23023 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBED010000032 DAVBED010000000
VERSION     DAVBED010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.032"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..337)
                     /locus_tag="VQ547_001265"
     CDS             complement(<1..337)
                     /locus_tag="VQ547_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543116.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSG"
     gene            complement(345..650)
                     /locus_tag="VQ547_001266"
     CDS             complement(345..650)
                     /locus_tag="VQ547_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2543117.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(637..831)
                     /locus_tag="VQ547_001267"
     CDS             complement(637..831)
                     /locus_tag="VQ547_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543118.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQ547_001268"
                     /pseudo
     CDS             complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQ547_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1228..1413)
                     /locus_tag="VQ547_001269"
     CDS             complement(1228..1413)
                     /locus_tag="VQ547_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543119.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQ547_001270"
     CDS             complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQ547_001270"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2543120.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3421..4119
                     /locus_tag="VQ547_001271"
     CDS             3421..4119
                     /locus_tag="VQ547_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2543121.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4162..5058)
                     /locus_tag="VQ547_001272"
     CDS             complement(4162..5058)
                     /locus_tag="VQ547_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2543122.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5067..6002)
                     /locus_tag="VQ547_001273"
     CDS             complement(5067..6002)
                     /locus_tag="VQ547_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2543123.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5999..6724)
                     /locus_tag="VQ547_001274"
     CDS             complement(5999..6724)
                     /locus_tag="VQ547_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2543124.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6808..7443)
                     /locus_tag="VQ547_001275"
     CDS             complement(6808..7443)
                     /locus_tag="VQ547_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2543125.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7445..8272)
                     /locus_tag="VQ547_001276"
     CDS             complement(7445..8272)
                     /locus_tag="VQ547_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2543126.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8294..8630)
                     /locus_tag="VQ547_001277"
                     /pseudo
     CDS             complement(8294..8630)
                     /locus_tag="VQ547_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(8631..9347)
                     /locus_tag="VQ547_001278"
     CDS             complement(8631..9347)
                     /locus_tag="VQ547_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2543127.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            9870..10481
                     /locus_tag="VQ547_001279"
     CDS             9870..10481
                     /locus_tag="VQ547_001279"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2543128.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10526..11254
                     /gene="rlmB"
                     /locus_tag="VQ547_001280"
     CDS             10526..11254
                     /gene="rlmB"
                     /locus_tag="VQ547_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2543129.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQ547_001281"
     CDS             complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQ547_001281"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2543130.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12270..12494)
                     /locus_tag="VQ547_001282"
     CDS             complement(12270..12494)
                     /locus_tag="VQ547_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2543131.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12572..13315)
                     /locus_tag="VQ547_001283"
     CDS             complement(12572..13315)
                     /locus_tag="VQ547_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2543132.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13315..14115)
                     /locus_tag="VQ547_001284"
     CDS             complement(13315..14115)
                     /locus_tag="VQ547_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2543133.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14273..14629)
                     /locus_tag="VQ547_001285"
     CDS             complement(14273..14629)
                     /locus_tag="VQ547_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2543134.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14642..15154)
                     /locus_tag="VQ547_001286"
     CDS             complement(14642..15154)
                     /locus_tag="VQ547_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2543135.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15154..15648)
                     /locus_tag="VQ547_001287"
     CDS             complement(15154..15648)
                     /locus_tag="VQ547_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543136.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15783..16229
                     /locus_tag="VQ547_001288"
     CDS             15783..16229
                     /locus_tag="VQ547_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2543137.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16226..16873
                     /locus_tag="VQ547_001289"
     CDS             16226..16873
                     /locus_tag="VQ547_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2543138.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQ547_001290"
     CDS             complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQ547_001290"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2543139.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQ547_001291"
     CDS             complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQ547_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2543140.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18503..19882)
                     /locus_tag="VQ547_001292"
     CDS             complement(18503..19882)
                     /locus_tag="VQ547_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2543141.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20177..21100
                     /locus_tag="VQ547_001293"
     CDS             20177..21100
                     /locus_tag="VQ547_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2543142.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21160..21765
                     /locus_tag="VQ547_001294"
     CDS             21160..21765
                     /locus_tag="VQ547_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2543143.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21783..>23023
                     /locus_tag="VQ547_001295"
     CDS             21783..>23023
                     /locus_tag="VQ547_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2543144.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6846 a         5158 c         4197 g         6822 t
ORIGIN      
        1 aaccacttcg acactgatca tggtggtaaa gcgtaatccc ttgtttctct gatttacctg
       61 acaaaaaagt ccaatagtaa gtcagctgac tatcactttc taagacccga taagaggttt
      121 catctgcatg aagaagaggt tgttctaaca acttttctcg taaaaggtta taaagggact
      181 ctaaatagta ttgactcgcc ttgatatgcc aattagcaat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattagg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaagctg agtcaatagt ctcgttataa aggggcttta
      361 ggaataggag ctttcacaat tttatcactc ggatttttat cactgcatgc ttggcatttg
      421 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac taattcttgt
      481 cgttgaaggg ttgctccaat ctcttttaga tctccctgac aatcagagca aatgctctct
      541 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
      601 ttagatttct tacgtttgta ggtaatttcc tctgtttcaa ctgggaacat ctccatcttt
      661 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
      721 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgaa gaagggcaag
      781 tgcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
      841 atgggcttcc cctccttgtt ttctaccttt attatactaa aaagaaagtc ctcatttcaa
      901 tagaaatcac gactttctga tggatttatt tttggagtga tagaaaagtc cttcataagc
      961 cagtctactt gttcagatgt gagagctttg acatcctttt ctgtactggg ccaagtcagt
     1021 ctgccgttcc caaagcgttt atatagtagc caaaatcctt gaccatccca gtaaagggct
     1081 ttaaagcggt atttacgtcc accacaaaag agaaaaactt gacctgagaa aggatctaat
     1141 tcaaagtggg ttttaaccag ataagccagt gaatcaatgc cttgcctcat atccgttttc
     1201 ccacatacga gatagacctg ccctaggcta gatagatgaa ttgtcataga gcaacacctt
     1261 atccaaaagc tgttctacca tttcgagatt gagagattga aaaaaactta cttcaagctt
     1321 gccaatacga attttaagca gaatatcatt tctcttttta gaatcaaaag gacgagattg
     1381 tggaatctct acaggaacaa taggttgtgg cattaaaata tcctccaata gttttacttt
     1441 actaatagta tacaggagga actccatgaa tgatagatac cttgttatga cgcgattact
     1501 atattagaaa gttggctctc taattaaatt aattctcatt atatatatca aaagaccgca
     1561 gcttgaaaac tacggtctaa ttttttgtcc aaatgtaaac cacttggaac tattattcaa
     1621 tttattcttt ttagtaaatg ttcccgtttt aatcccagtt acagttttta atcctctgta
     1681 accgttgatt ttacaaagct tttaattttt ttgcgattat tcccactcaa ctgttgcagg
     1741 tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg
     1801 tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc
     1861 gatagaagtg atagcacgga ttgcaatcgt gtagtcatat gtacgaccgt cacccataac
     1921 accgactgaa cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc
     1981 agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc
     2041 ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca
     2101 tacgatatgg tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag
     2161 agtattgagt ggttcaatca attcaaactg catatcttct ggaagaccac ccacgttgtg
     2221 gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt
     2281 accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac
     2341 aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc
     2401 aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat
     2461 gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat
     2521 caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc
     2581 tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat
     2641 gtcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt
     2701 acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta
     2761 aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg
     2821 aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc
     2881 atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc
     2941 acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg
     3001 cataccataa cagattccca aaattggaat tccgagttcg aagatttctg ggtcaatatc
     3061 aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt
     3121 gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat
     3181 ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat
     3241 tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa
     3301 atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag
     3361 tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat
     3421 atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt
     3481 tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt
     3541 cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt
     3601 gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc
     3661 agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac
     3721 aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat
     3781 attatccgaa tggagcgggt ccgctatgcc gaccaagttc ccctagttta tgaagttgct
     3841 tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcacaag tcatttcttc
     3901 caaaccttgc aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc
     3961 cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga
     4021 ttgacccagg tttcctacct agaagatggt actgcttttg aatacgtaaa aagtcaatat
     4081 gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct
     4141 gtcacggaca aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt
     4201 tacagcaaac aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat
     4261 tattaagaag gcaaagaaaa tcgccgatat tggctcaatt gaagccaaca agcttgactt
     4321 gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaga cagtcccgat
     4381 aaggataatg cctgcaaacg caaggagaaa atcaagacta gtcgggatat cggcctgtag
     4441 aacccctgta aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgagcaa
     4501 gctgctcccc cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa
     4561 ggcagaaaag agaccccaga acagaccagc aggtgtcatg gataactggt ccaactgccc
     4621 atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag
     4681 tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag gacaaacata
     4741 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     4801 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     4861 taaaaagacc agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc
     4921 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     4981 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     5041 ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga
     5101 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     5161 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     5221 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     5281 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt
     5341 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     5401 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     5461 ggcccaaact tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     5521 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     5581 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     5641 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     5701 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     5761 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     5821 ttgctgacac tagctagatc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     5881 tcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     5941 ccgggataaa ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     6001 atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag
     6061 acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt
     6121 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     6181 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     6241 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     6301 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     6361 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     6421 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     6481 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     6541 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     6601 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     6661 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     6721 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     6781 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg attttgacaa
     6841 agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     6901 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     6961 tgcaagctct tgataggctt gattccagtt ctgaattttt tcattcgagc ggatatagac
     7021 tgcctgctgg tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     7081 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     7141 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     7201 tccaccatat agatgagcat caagattctc tagtaacagt cctgtctgat agccacgaat
     7261 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     7321 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg
     7381 atacttagtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     7441 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     7501 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     7561 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     7621 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     7681 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     7741 caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     7801 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     7861 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     7921 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     7981 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca
     8041 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     8101 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     8161 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacccc
     8221 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     8281 ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     8341 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca cccctctata
     8401 aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg tgaaaaggtt
     8461 ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat agttgttttt
     8521 ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca cttagcattc
     8581 tcttcatctc ccatagattc aatccgttga ttggaaatga agttccccat ttaatagata
     8641 atgagtttct tatctccatc tttttcaacc gttttagatg gttcaacaac gtgaggatgc
     8701 cctccaaaga taatatccgc tccccaatcg atcatcttgt gataaagagc tttttgttct
     8761 tcagttggtt ccaatcgata ctcaacaccc atctgaggca tgataatggt gatatctgct
     8821 tccttctctg cccgttcgac ttcagccttt atcttatctt cgtttaaatc tgaaagataa
     8881 cgattatagt cttcctgaaa aatatactgc tcaattccat tgaaaccata ggaataggct
     8941 aacaatgcaa ccttgatagc attcacttcc ttaatgacca gcggagcctg atcacgtggt
     9001 tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc ggccattgaa
     9061 ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag cacatgataa
     9121 cctgcttcct taatagcatc cataacttca acaggagcat taaagagaag ataacccgct
     9181 aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc tgcttgcttg
     9241 agccaaggag tcacatactc aaaattttca tgaaagtcat aggtaccgtc ttctttttta
     9301 gctgaaaaga aaagtccatc gtggtagagc aaatccccgt gggccataat tctggcagtt
     9361 ttttcctctt cctactcctg agacttttgc ttagtcccct cttgagaaat agtatctcgt
     9421 ttttgactag tcaagggatt ccttggaagc tttcaaacaa caagaccaag cccattgata
     9481 aaccaactgc tagcaagagt atcgccacaa atcccttatt gctccacttg cgataactcc
     9541 taaaaagttt accaagccct tcataaaacg aaaagctaaa ccaccctgat ttcgattttg
     9601 tcttctttgt atcttcattc tccctacttt cttatgcaag ccttttcttt ttattatatc
     9661 acagataagt atttctttca caattgaatt gaacttccca tctattttct ataaatccta
     9721 aatgccataa tgctttcaat tcttgtcatt ttgtgatatc atgtagaggt aatgaaagga
     9781 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagttaa
     9841 ctgcactaaa cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg
     9901 ctcacttaat tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcgcgattg
     9961 ctgaggaagt cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc
    10021 aattccttaa acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg
    10081 ttggactggc tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta
    10141 atattgttga agaaggcgaa actccacagg aagcctacga tttggaaggc attatgtaca
    10201 atccaaaaat cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc
    10261 tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact
    10321 actttgacaa agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg
    10381 ttcagcatga aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag
    10441 acccatttgc agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga
    10501 cggggttttg tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc
    10561 cgttaccgaa gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg
    10621 aggtaagaat gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg
    10681 gacatcaaaa aaatctctct ctgagatgac tgaaggtgct gttcatcaag gttttgttct
    10741 acgagtgtct gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga
    10801 agaaaatcca cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat
    10861 cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtgctgt
    10921 cggagtaact cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc
    10981 ccgagtgaca aacctcagtc aaaccttaga taaactcaag gatgaaggct tctggacctt
    11041 tggaacggat atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct
    11101 catcatcgga aatgaaggaa aaggcatctc tagcaacatc aaaaaacagg tcgatgaaat
    11161 gattaccatt ccgatgaatg gacatgttca aagcctcaat gccagtgttg ctgcagccat
    11221 tctcatgtac gaagtttttc taaatagact ataaaaaagt ttccagtcat ctgattggaa
    11281 acttttttat gattaactat gttctgtgat aaacttgtag gcttcttgac cagcgatagc
    11341 tccatctcca actgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc
    11401 aaagataccg tcgactgcag tcttcatgtg gctatctgtc acaatccagc ctgcctgatc
    11461 ttggatattc aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac
    11521 accaccgaag gcttgctctg tcacttgacc tgttttcaca ttttcaaaaa cgacagattc
    11581 tactctgttt tcacccttga tttccttcac tacagaatcc cagataaagc tgattttttc
    11641 attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac
    11701 aatggtaaca gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc
    11761 accaccaact accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta
    11821 agaaacacca cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga
    11881 accagttgct acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt
    11941 aaaatcacca tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt
    12001 ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg
    12061 gtaattttcg atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa
    12121 agctactttt agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc
    12181 accgataata atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt
    12241 ctaactcttt cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata
    12301 accgcaaagg ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg
    12361 gcttggcgag ccctggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc
    12421 cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat
    12481 agttgcagta gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc
    12541 caactaactg agttttcctt tatctattat atcaaatata agtccgtttg taactagcga
    12601 agaattcttt tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact
    12661 cgatgatttt ccccttatct aataagagaa ttttatccgc aacttgggct acaaaggaca
    12721 tgtcatgact gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt
    12781 ctacttcacc gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat
    12841 ctggtttcat agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat
    12901 ggcgaggata atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa
    12961 tcttagtcgc ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat
    13021 caagtgctgt tcgacgttca aataaattaa actgttggaa aaccatagac aacttacggc
    13081 gtagggcaag gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct
    13141 gaatagagcc actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc
    13201 cagctcctga agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagttcagat
    13261 gatccaagac agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg
    13321 aaggtctcct ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc
    13381 gatgaaacga ccgaggcttt caattccgat attgactacc caataaacaa gggcaacaga
    13441 gatgaagcgt tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac
    13501 ttccacaaca cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt
    13561 aatcaaggtt ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg
    13621 cgctcgggtc atacccagac tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat
    13681 ggctgcacga atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc
    13741 aaaagctgca gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc
    13801 tttcaaagcc aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc
    13861 ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt
    13921 cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat
    13981 aattgttgtt ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct
    14041 aaacagcttg ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat
    14101 cgttgtaaca ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc
    14161 cgtcaatgaa attatttgct acggtcagat acagactttg tctacctact agtttatcat
    14221 actttgaaac agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca
    14281 gtcccagttc ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta
    14341 aaatgggccg ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg
    14401 acaaacttcc taccttatct tttagcccta attcacggta tttgatacca ctggtgttga
    14461 aaaattgctt caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag
    14521 gtgtttcttc cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt
    14581 ttgctttttt acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct
    14641 tctatttgtt tatatcttta aaatctacgc cttcatgctc caagagccaa gctttctttt
    14701 ccactcctgc agcatagcct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    14761 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    14821 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    14881 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    14941 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    15001 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    15061 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    15121 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    15181 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    15241 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    15301 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    15361 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    15421 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    15481 caaggctacg taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata
    15541 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    15601 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    15661 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    15721 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    15781 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    15841 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    15901 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    15961 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    16021 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    16081 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    16141 ctattatcca aaccagctgc caaaccgtca aactctatca tcaaactcta gacttaatcg
    16201 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    16261 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    16321 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    16381 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    16441 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    16501 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    16561 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    16621 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    16681 tctggctatc attcctgcca ttatcagtca aacgacaccc gttttctgga gtctcatggt
    16741 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    16801 ccacatgatt tggcatctct ttatcctagc tgcgtccgca cttcaataca tcgctattgt
    16861 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    16921 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    16981 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    17041 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    17101 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    17161 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccagcaaaat
    17221 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    17281 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    17341 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    17401 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    17461 tattccaatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    17521 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    17581 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    17641 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    17701 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    17761 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    17821 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    17881 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    17941 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    18001 cttgtccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    18061 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    18121 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    18181 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    18241 accagcagct tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc
    18301 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    18361 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    18421 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    18481 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    18541 tgtatggttt attgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    18601 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    18661 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    18721 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    18781 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    18841 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    18901 cacaagcgtt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    18961 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    19021 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    19081 tcttaccatc agcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca
    19141 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accatcacct tcgattgctt
    19201 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    19261 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    19321 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    19381 caacggcgat acggtcgaga tgttggctct tgtcagaaag tttattgata acttcttcag
    19441 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc
    19501 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    19561 tcaatttctc gtatgattct ttgtgttctt ttccttcaac ttctgctgta accactttgt
    19621 tatcatagtc gattgaaaga actggtgaat tcatataaac cttagcacct ttagcttcta
    19681 atttgtcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    19741 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    19801 tctcatttcc aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac
    19861 cgactacaac gattttactc ataaaaaatt tcctgccttc attctaaatt tactttacta
    19921 gtataccatt taccgttagc gtttacaagg gggggactat tatttcagca ttttttatca
    19981 aaaataattc cccatttatc ctgttttcaa gcctcatgaa ttttatgagc atatttcttg
    20041 actttttcca aattttgttt gtgaaaattc taactttatg gtattataat aacatgaaaa
    20101 taaaatgtaa gggcttcaat ttagatgatt atttgatatt gcaacttatt ttctataaga
    20161 gaaaggagtt ggtagcttga ctcttcgttc acattctgaa cggctaatgg ggactactat
    20221 cactatttca ttagtggatg agcaagccga tatctttctc caaaaatcct ttgacttgct
    20281 caaagagctt gaataccgct tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa
    20341 ttatcaagca ggaatatccc ccgtcacagt tcatccagac ctgtttgagc tgatttcact
    20401 tgggttagag catagcctag cgctctctag ccacctcaat atcagcattg gtcccttaat
    20461 tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag aaattgaatc
    20521 ggtgctgcct ctaatcaatc ctcatggtat cgagttagat tcttctactt ctactgtgtt
    20581 tttaaaacag aaaggaatga agatcgatct aggttgttta gccaaaggat acagtgcgga
    20641 taaggttgcc caatttctta ggaaagaggg ggtgacttct gccttgatca atctgggagg
    20701 gaatatcctg accattggaa aaaatcaggc aagaggggat aacccatggc aaatcgggat
    20761 tcaagaccca gccaatccta ggggaaatca tttaatgacc atccctgttg tcaataaatc
    20821 tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc gatggacaag attaccatca
    20881 catttttgac agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc taacaatcat
    20941 ctctgataaa tcagtcgatg gcgaaatctg gacgactcga ctctttggag aaagacctgc
    21001 ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca tcgataaaga
    21061 aggccaccta agctgttctt caggaattcc tactctatag agacaactgt ttcaatggaa
    21121 ttttaaaatt gtattatgta aaaagagaaa ggaaatatca tgttaaaact tattgctatt
    21181 gttggaacaa attcaaaacg ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac
    21241 tttgctgaca aagctgaaat tgaacttgtt gaaatcaaga ccattcctgt cttcaacaaa
    21301 ccagctgaca agcaagtacc tgctgaaata ttggaaattg ctgctaaaat cgaagaggca
    21361 gatggcgtta ttatcggtac tcctgagtat gatcactcta ttccagctgt tttgatgagc
    21421 gctcttgctt ggttgtctta tggtatttac ccacttttga acaaaccaat catgattaca
    21481 ggtgcttctt acggtacgct tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg
    21541 aatgctcctg aaatcaaggc aaatgttctt ccagatgaat tcttgctcac acactctctt
    21601 caagcattta acccaagtgg cgacttggtt gaccttgatg ttatcaagaa attggatgcc
    21661 atctttgatg acttccgtat cttcgtgaag attactgaga aattgcgcaa tgcgcaagaa
    21721 ttgcttcgca aagatgctga agactttgac tgggaaaatt tgtaagatag gagaccgaaa
    21781 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgcaaactct
    21841 tggaatttat ccgtcgcaat ttcaaattca aatttgaatt agaagtactt gaaatcgacg
    21901 aagttccaat gtttaaccaa gacgaaaaat gggacgaaag cttccaattg cgtttcttgt
    21961 ataacaagat tacacgtgct gatggtgtca ttatcgccac tcctgagcac aaccacacta
    22021 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    22081 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    22141 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    22201 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    22261 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    22321 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    22381 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    22441 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    22501 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    22561 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    22621 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    22681 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    22741 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    22801 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    22861 actggtacct aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg
    22921 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    22981 gaggccacgg tggtgacgca gacgctacag ccggtgcaag tta
//
LOCUS       DAVBED010000033        22314 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBED010000033 DAVBED010000000
VERSION     DAVBED010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.033"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ547_001296"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ547_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2543145.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ547_001297"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ547_001297"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2543146.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ547_001298"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ547_001298"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2543147.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQ547_001299"
     CDS             complement(3954..5222)
                     /locus_tag="VQ547_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2543148.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQ547_001300"
     CDS             complement(5342..5710)
                     /locus_tag="VQ547_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2543149.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQ547_001301"
     CDS             complement(5703..5969)
                     /locus_tag="VQ547_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2543150.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ547_001302"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ547_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2543151.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQ547_001303"
     CDS             complement(9537..10106)
                     /locus_tag="VQ547_001303"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2543152.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ547_001304"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ547_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2543153.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQ547_001305"
     CDS             complement(11376..11570)
                     /locus_tag="VQ547_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2543154.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ547_001306"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ547_001306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2543155.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ547_001307"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ547_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2543156.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQ547_001308"
     CDS             complement(14504..15262)
                     /locus_tag="VQ547_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2543157.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQ547_001309"
     CDS             complement(15320..16501)
                     /locus_tag="VQ547_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2543158.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ547_001310"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ547_001310"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2543159.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQ547_001311"
     tRNA            17207..17280
                     /locus_tag="VQ547_001311"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQ547_001312"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQ547_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2543160.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQ547_001313"
     CDS             17591..18916
                     /locus_tag="VQ547_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2543161.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQ547_001314"
     CDS             18913..19665
                     /locus_tag="VQ547_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543162.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQ547_001315"
     tRNA            19717..19788
                     /locus_tag="VQ547_001315"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQ547_001316"
     tRNA            19794..19867
                     /locus_tag="VQ547_001316"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQ547_001317"
     CDS             complement(19908..20450)
                     /locus_tag="VQ547_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2543163.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQ547_001318"
     CDS             20629..21396
                     /locus_tag="VQ547_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2543164.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQ547_001319"
     CDS             21481..22161
                     /locus_tag="VQ547_001319"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2543165.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6901 a         4110 c         3643 g         7660 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggtgttt tattatgaaa ttaa
//
LOCUS       DAVBED010000034        22104 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBED010000034 DAVBED010000000
VERSION     DAVBED010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.034"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..389)
                     /locus_tag="VQ547_001320"
     CDS             complement(<1..389)
                     /locus_tag="VQ547_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2543166.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
     gene            complement(386..550)
                     /locus_tag="VQ547_001321"
     CDS             complement(386..550)
                     /locus_tag="VQ547_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543167.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(849..968)
                     /locus_tag="VQ547_001322"
     CDS             complement(849..968)
                     /locus_tag="VQ547_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2543168.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ547_001323"
     CDS             complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ547_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2543169.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ547_001324"
     CDS             complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ547_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2543170.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ547_001325"
     CDS             complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ547_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2543171.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2485..3072
                     /locus_tag="VQ547_001326"
     CDS             2485..3072
                     /locus_tag="VQ547_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2543172.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            3065..4654
                     /locus_tag="VQ547_001327"
                     /pseudo
     CDS             3065..4654
                     /locus_tag="VQ547_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            4665..6026
                     /locus_tag="VQ547_001328"
     CDS             4665..6026
                     /locus_tag="VQ547_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2543173.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            6083..6238
                     /gene="blpC"
                     /locus_tag="VQ547_001329"
     CDS             6083..6238
                     /gene="blpC"
                     /locus_tag="VQ547_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2543174.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(6282..7622)
                     /locus_tag="VQ547_001330"
     CDS             complement(6282..7622)
                     /locus_tag="VQ547_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2543175.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(7636..8373)
                     /locus_tag="VQ547_001331"
     CDS             complement(7636..8373)
                     /locus_tag="VQ547_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543176.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8378..8716)
                     /locus_tag="VQ547_001332"
     CDS             complement(8378..8716)
                     /locus_tag="VQ547_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543177.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8993..9322
                     /locus_tag="VQ547_001333"
     CDS             8993..9322
                     /locus_tag="VQ547_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2543178.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9490..10539)
                     /locus_tag="VQ547_001334"
     CDS             complement(9490..10539)
                     /locus_tag="VQ547_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543179.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10536..11267)
                     /locus_tag="VQ547_001335"
     CDS             complement(10536..11267)
                     /locus_tag="VQ547_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543180.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11335..11745
                     /locus_tag="VQ547_001336"
     CDS             11335..11745
                     /locus_tag="VQ547_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2543181.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11755..12042
                     /locus_tag="VQ547_001337"
     CDS             11755..12042
                     /locus_tag="VQ547_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543182.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12204..12443
                     /locus_tag="VQ547_001338"
     CDS             12204..12443
                     /locus_tag="VQ547_001338"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543183.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ547_001339"
     CDS             complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ547_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2543184.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(14134..14487)
                     /locus_tag="VQ547_001340"
     CDS             complement(14134..14487)
                     /locus_tag="VQ547_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543185.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ547_001341"
     CDS             complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ547_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2543186.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ547_001342"
     CDS             complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ547_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2543187.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ547_001343"
     CDS             complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ547_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2543188.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18552..19061)
                     /locus_tag="VQ547_001344"
     CDS             complement(18552..19061)
                     /locus_tag="VQ547_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2543189.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19669..21606
                     /locus_tag="VQ547_001345"
                     /pseudo
     CDS             19669..21606
                     /locus_tag="VQ547_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            21604..22104
                     /locus_tag="VQ547_001346"
                     /pseudo
     CDS             21604..22104
                     /locus_tag="VQ547_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6993 a         4580 c         3952 g         6579 t
ORIGIN      
        1 ttcaagcccc acatgagcag aagcatgatg attaagcaga gaacagcgcc aatataagcg
       61 attatttgtt ggtaggattc tcctgctgtg atacctctat acaaacaaat aatagacata
      121 aaacctgtca agccgatgaa cataagttga ttggttctag gactaaccaa atcatcatct
      181 tcaaactctc ttatcctcat ttccctagtg agataaacag taaccaaaat agaagccaag
      241 ttaataacta ctaaaagaaa ttggaaaact acggaaaaat ttaaaaactg acgagataga
      301 aatagataag tagaaacaag caagggcaac tgacctaaga acaatctcgc aaggaagatg
      361 ttccgttttt tagcaaaaaa agttttcatt tcttttctcc tttcttttta ttgatagcaa
      421 aatagatcat aactgcaatc acataggcta tggtataaaa tagctgatac caagcactct
      481 ccctaagcgg atatagaaag atggacatga ttagatacag aacgaaaata atcagtattt
      541 ttttcttcat aagatttcct cctaaatgtg cgatttatct tagttgagca agaacattta
      601 cactgctagt atagcactta ttttgacctt ggatcactca aatcataaat ggtcatcgaa
      661 acatcttgaa ttgttaaaaa atttaaaaag taagcattaa aaacatactt tcctctttat
      721 attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata tcattttgac
      781 aggcgaaaca aaattaaaga aactcccctg taaattaagc tagcaaatac aggggagaaa
      841 tttatttttt agggggtact atctgtatcc tttttgggaa attttgaaaa tatttttcta
      901 attaaattat acatataagg accaaatata ccaactacta aaccaataat aaaactttta
      961 aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt atagctccac
     1021 ccgcagcacc agttgctgca ccttgccatg ttcctgtttt aatgcctagt tgaagacctc
     1081 ttgctgctgc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
     1141 caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt tttgtatcca
     1201 tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct cataatttta
     1261 ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta agcatgttaa
     1321 tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc cagctactcc
     1381 taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga ctcctgtaat
     1441 cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa gcatttcagt
     1501 atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct cctttttatt
     1561 ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gattttttat agtatctttt
     1621 tgattttctt aaaaaagtat atacgtctac tatcttctta aaggtagcag tacctatttt
     1681 ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt tattctcctt
     1741 gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa tattagtaaa
     1801 taatagttta tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac
     1861 gattacataa acgattgata atataattaa aattttgcta actatcttat tctcatcatt
     1921 cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat
     1981 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
     2041 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
     2101 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
     2161 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
     2221 tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat cgttttttaa
     2281 aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattagctt ttttatttca
     2341 agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca ttcaggaagt
     2401 tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat aatagaccta
     2461 tccactatat gaaaagaatt gccaatgact tcttataaac gtacatttgt tcctcaaata
     2521 gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta tggttcagat
     2581 ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac gactgctctt
     2641 ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca agcagataaa
     2701 acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa caaagaagga
     2761 aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat tattggtgat
     2821 cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta tgaatggact
     2881 ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga taaaaagaat
     2941 ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
     3001 tgttctctca agcttattgg tcactattat caatataggt ggttcttact atctccaagg
     3061 aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca tctcagttgg
     3121 tctggttatc acctaggtta tcacctatat cctccaacaa gtcatgagct tctccagaga
     3181 ttatctccta accgttctga gccagagatt aagcattgat gtgattttat cctatattcg
     3241 ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag aaatcatttc
     3301 acggttcaca gatgctaact ctattataga tgccttggct tctaccattc tttctctttt
     3361 tctggatgtt tctattctga ttcttgtagg gggagtcttg ctggcacaaa accctaatct
     3421 cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt cttttatgaa
     3481 accttttgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta gctctgccat
     3541 tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag aaaatcgcta
     3601 tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc tcagtaaata
     3661 ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata tccttatcct
     3721 atggtttggc gctcaattag tcatgtcgag taaaatttct atcggtcagc tgattacctt
     3781 taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc tccaaaccaa
     3841 actcccatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag tcgaatctga
     3901 atttcaagtt caagaaaacc ctgtccattc acattttttg atgggcgata ttgaatttga
     3961 tgacctttct tataagtatg gttttggacg agatacctta acagatatta atctcacgat
     4021 taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa caactttagc
     4081 caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca atcatcagga
     4141 tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac cccaacaagc
     4201 ctatatcttt aatggctcta tcttggaaaa tttaaccttg ggcggtaatc atatgattag
     4261 ccaagaagat attctaagag cttgtgaatt agctgaaatc cgtcaagaca ttgaaagaat
     4321 gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag gacagaagca
     4381 acgaatagcc ctcgctcgtg ctcttttaac taaatctcct gttttaatac tagacgaagc
     4441 tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta tgtccctaac
     4501 tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa ctaaccgtgt
     4561 cattgttctt gaccagggga aaatcattga agttggtagt caccaagagt taatgcaggc
     4621 gcaaggcttc taccatcatc tgttcaataa ataaggagaa tgtcatgaat cctaatcttt
     4681 ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg ttaattatac
     4741 ctctttcatt actgtttact ttcatcttga ttttctccct tgttgccaca aaagaaatta
     4801 ctgttacttc ccaaggagaa atcgccccta caagtgtcat tgcatccatt cagtcaacca
     4861 gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa aaaggtgact
     4921 tactcatcaa atactctgaa acaatggatg agagtcagaa aactgcctta gaaactcaat
     4981 tacaaagact tgagaagcaa aaagaaggac ttggaatttt gaaacaaagt ttagaaaaag
     5041 cgactgatct tttttctggc gaggatgagt ttggctacca taataccttt atgaatttta
     5101 ctaaacaatc ccatgatatt gaactgggta tcacaaagac taacaccgaa gtttcaaatc
     5161 aagctaatct tgccaatagc agttcatcag ccatcgaaca agaaattaca aaagttcaac
     5221 aacaaattgg agaatatcaa gagttgagag atgctatcat aaataacaga gcacgcttac
     5281 caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct caaggacaaa
     5341 cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt gcaagtcttg
     5401 aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta gcaacttatg
     5461 ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa acagcctcac
     5521 agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta gatcaagcga
     5581 cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt catctgaaca
     5641 gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa atattccctg
     5701 tcatcacaga tacaagagaa gtactaatca cttactacgt atcatctgac tatctcctct
     5761 tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat cacggcacca
     5821 ccatcatcgg ccaacttcag agtattgatc aaactcctac cagaacagag caaggcaatc
     5881 tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc atccaatatg
     5941 gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat tatttcaaag
     6001 ataaaatttt aacacattct gattaatttt cagataacac tctataacta tttattatct
     6061 tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat ttcaagaact
     6121 aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt tcttatatag
     6181 atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac aactataaaa
     6241 aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat atgtattaca
     6301 gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt attgggatga
     6361 ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc tttagaactt
     6421 gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga attttcaatg
     6481 ataaaggtct cctgtgctcc attttttaaa aaggcaattg aaacatgagg ttgacaggct
     6541 tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag aaaatcaagt
     6601 agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac aatgttctta
     6661 tctctagctt ttagaaattt ccctgctagg agacttttga gggctttatc acgaatattc
     6721 accaatcgac caaggtcata tttattgtcc tgcaattttt cactagaatc ctttaagacc
     6781 gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccag acgtaagcta
     6841 gtcaagaggt tggtgtagtc atggcgaaaa ctccgtactt ccttataaag ctcctctata
     6901 tgccgactat accgctccat ctctctgtag cgcaagtcct gctcttggtt cagtctctca
     6961 tggagtttgt ccttcaaata ggtatccaat ttcttgataa tccccataaa aaagagcagg
     7021 taaaagacta ggatgagatg gcgaacagtc gttgattgaa tcccctgttc atattcaaag
     7081 taagacagat tttgtatcac caaatagtaa gcccccatta tccagttaat ctgagtcagg
     7141 gacttttgaa aatctttatc gagaatcccc tttctcaagc tagtgaaatc atagtccaac
     7201 catttcaaaa aagctagaga aatgaagaaa ttgaaaatta ttatacataa ccaaataaat
     7261 gagtagtcat catatacttg cccttgtccc aaaaatggaa gcacaaaata ggaaacacct
     7321 ctataaaaga gattcactaa tatcattgga aagagaccat aaaagagaag gagtttttta
     7381 ggaagttctc ttaacaataa gaaagataag cctatgccgt acaagggttc cataaaataa
     7441 gatagataag tatttcctac catatagcca agcattccaa aaacaacggc caacagtatc
     7501 ttaaaaagaa aggccttaaa aatcctctca aaagtgagac taattccatc taccttaaag
     7561 aatatgacaa tttttaatcc gtgagtaaca agtgtataca acaatatcca agcaacattc
     7621 ataaactctc ctagctcagt gtaagttatt aatagcctca gacacttccc tgaccttata
     7681 acgcgcgatt agacaacttc caccattggg aaagaaaagc agtttttctt tcttatctaa
     7741 atgcaccaca ttggcaggat tgatgagaaa agagcgatgg cactgcaaga gacgaggctc
     7801 ctgcttgaga acctcctcta gactcgctgt aaattccagc ctgtctgtct tggtatagag
     7861 aataacacga tggggtcttg tggacgtttc gagatagtaa acctctttaa aaggatactg
     7921 gaattgagca aattttgatt taaagtaaaa gcaatcttcc gctagacttt tactgtcttg
     7981 accattggca tagaggaggg ctgtctcgat acgagattca aactcctctg ccgaaagggc
     8041 cttatcaata tagtccagag cagacacttg gtagcgaaag gacaggggca taaactccga
     8101 gtgagtcgtc acaaagacaa tcagggcata cggatcccga tcccgaatct ttctagccac
     8161 ttccagaccc ttcatctcct catttcgaat ctcaatatcc aaaaagaata gctgatgggc
     8221 ccccttctca tgcacctctg ccagcagttg gtctggcttg ccaaatacct caaaagagct
     8281 gggagtgata tgatgttcct tcaagagttt ctcaatcgtc gtttcaatcc tagtctgttg
     8341 ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct ttcaaccatt
     8401 tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga ccttcttctc
     8461 cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga ttaaccaaac
     8521 aatttcgatg acatctcatc aaggtttccc catattggtt ctcaagatta cttaaatttt
     8581 gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct ttagttggat
     8641 gtgtttggat atagtagata tcgtcgacgt ttactttata gactgttttc tgcgtctgaa
     8701 taatcatatg tttcattgga ttctcctcct aagaaaagaa taacagaaaa gttctagccc
     8761 aagcccaccc aatcctaaac agtctttgaa agctcctaaa aggattattt ttctacaaca
     8821 tcatgatgag cttacaacta ttttatcata aaattcactc agcgcaattc aagacatttc
     8881 aatgacaatt aaagatttga ataaaaaaaa agaattaaaa atgataaact aacagtatca
     8941 aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc ccatgacaga
     9001 tacagacccc atcaaaagag ctcatacttt gattactgac ttaaacaaag cctaccaagc
     9061 atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact ctattcttgg
     9121 ttttttagcc aaggctgaaa cagtggataa tcgattcttg attgaactag aaaaatttta
     9181 ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc caactcgcgc
     9241 cgcttggcgg gcctatgacc gcttccactt tgaccaagtc aagaccaagt taatactcaa
     9301 tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     9361 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     9421 cctgtagtaa caaaaaagaa gctgagacag actgaactca acttcttttt tagtgtcgta
     9481 tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     9541 aaccaaacca gctcctagta aggctagaag ggccagtttt tcttggaagg taatcaaccc
     9601 aacaactaat tccacaagta aaacaaaact ggtcaatcct cgaactacct cctgtaagcc
     9661 tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt agtcaaaggc
     9721 atgatagagg gccagcaact ggaagagcaa gaggtagtta aagagaacta ccactgctgt
     9781 cgcaatccaa gcttgctcga taaaaacctg cgccagtacg gaaagtaata gaagacgaag
     9841 actgagagca aagaggtcgc catttcgcag ataagaacgc agatagagat tttgccaaat
     9901 cttcccaggc accttctgaa cagcctttaa gataaagtcc agataggcac gacgcttaac
     9961 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
    10021 acgcttgctt tcttgagaaa taacatagtc ccagtccagt ccagtttcag taaaaaattt
    10081 gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca catatagcag
    10141 aaaaactggc aagccataac ccattgctaa aaataaaggc gcaaataaca gcaagaaaag
    10201 ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga gatggagctt
    10261 gattgcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
    10321 tcctccccaa agtaagagta aaacagacgt aattcctaca aacaaaagga taggccaatg
    10381 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
    10441 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
    10501 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
    10561 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
    10621 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
    10681 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
    10741 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
    10801 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
    10861 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
    10921 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
    10981 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
    11041 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
    11101 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
    11161 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
    11221 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
    11281 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
    11341 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
    11401 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
    11461 ccaaaagaac actatcgcaa tcttttggag atgaatgcta cgagcgccag ccaactcttt
    11521 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
    11581 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
    11641 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
    11701 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
    11761 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
    11821 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaagac
    11881 gatgtggata ttatccaaaa tagcctgcaa atcatcgacc agcaaaaaga acttatcaag
    11941 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
    12001 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc ccccggctct
    12061 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
    12121 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
    12181 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
    12241 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
    12301 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    12361 tcagtaacca tacccatgac aagccgacgc tgacgtggtt tgaagaaatt tttgaagagt
    12421 atcattcacc atttcacaac taaatcgaag actttctgcc gtaatgaaaa cacctgaaac
    12481 agcttggttt cagctgtccg gaaactttaa gacttaggtt caaagtttag gtatggaact
    12541 tcgaaggagg tcgctaccgt ccgtcattac ttaggaaagt cttaaaaaat ctataaagta
    12601 aaaagagccc gacagctctt tttgtttata ctcaatgaaa atcaaaaagc aaactaggaa
    12661 actagccacg ggctgctcaa aacactgttt tgaggttgta gatacgactc acatatatac
    12721 ggcaagccga cgctgacgtg gtttgaagag attttcgacg ctgacgtggt ttgaagagat
    12781 tttcaaagag tattattctc catcaaaggc atctttaata tggtcaaaga agcctttttt
    12841 ctttggattt actttcaagt caccagcagc cgcgaattct ttcaaggcta ctttttggcg
    12901 gtcgttcaag cctgtcggtg ttacgacatt aacagtaacg tattggtcac caactgcacc
    12961 gccacgaagg ctcggtgccc ccttactacg taggcggaat ttcttaccag tctgagttcc
    13021 ctctggaata accaattcaa catcaccgtg aacagttgga atatctactg tatcaccaag
    13081 agccgcttgg acaaagttga ggttgagatt gtagaagata gtcgttcctt cacgttcaaa
    13141 cttgtcgcta gcttctacag aaactactac atacaagtcc ccataaggtc caccgttaaa
    13201 gcctgcttcg ccttgaccag cgaggcgaat ttgttgacct gtttccacac cagcagggat
    13261 tttcacatgt acgctatgag cttgtttctc atgacctgtt ccatgacagg ttgtacatgg
    13321 atatttgatt tcttttcctc gaccgtgaca gacatcacag gttacttggc gacgcatcat
    13381 accaagagga gtctgcgtat cgacgttaat gacaccagcg ccatgacagc gtccacaagt
    13441 gactggactt gtccctggct tagcaccaga gccattacat gtacgacagc cagcttcacg
    13501 atgatactta acttccttct cagttccgaa gatagcttct tcaaaggtca aattgacacg
    13561 atactggaga tcatctcctt ggcgaggagc gtttggattg cgcgaagaac cgcctccgcc
    13621 gaagaaactt gaaaaaatat cctcaaaacc accgaagcca cctgccccat tgaaaccacc
    13681 gaaaccacca gctccaccaa aaccaccatt ggcgcctgca gcaccatact ggtcataggc
    13741 agcacgtttt tggtcgtcac tcaaagtctc ataggcttct tgaacttcct tgtacttgtc
    13801 ctcagcacca ggctccttgt tgatatctgg gtgatatttt ttggaaagct tacgataagc
    13861 ctttttgatc tcgtctgccg aagcgttttt tgacaccccc agacgatcat aaaattcagt
    13921 attgttcata caagatacca agaccgtaaa attcgactga aaaataggaa atctgacgct
    13981 ggagcgacgc tcctagacag atttctcttt tttccgagaa tttaggtcgg gttcaattcc
    14041 tttcttttat attgatgaga taatactcca gccactcggc cctatccctt tttaccgaaa
    14101 aacagaggct gagttgcaac ctctgtggtt agattattca tttgaaataa aaatggttgt
    14161 attatctcta gtagtaatct tcaaagacct tttagctaaa tcaaactcaa atttattata
    14221 gtgtgggtct tgtgttttat ataggtgtaa ctcctgacat atatgatccg aaaagtaaat
    14281 cataacatct ttaaacacag aagtgtggtc atatttactc ttaccaacag ctacttctgt
    14341 aaattcttta taaatgacat ttccatttct ttccacagtc accagcattt ctgttggatt
    14401 ataatccaaa ttaaataatt cttcaaaaaa ctttatcttt tcatgataat ctgcaatgtc
    14461 agaaagatta tttttattaa cactcataac actagcccct tatttttcag taaactctcc
    14521 gtctacgacg tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc cttcttgagc
    14581 ttgttgcgct gctgcagctt gttcgtagag tttaacagca agtccttgag ctttttcgtt
    14641 caatgcttca agttttgctt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag
    14701 gtcatcaagg gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc
    14761 cttgattgtc ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc
    14821 ttctttacgt ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat
    14881 ttcttcgtca gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc
    14941 aaggtctttg gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat
    15001 ttgaggaatt ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt
    15061 gttatctgct gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt
    15121 gtctgctgct gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat
    15181 aagttttgta aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag
    15241 aaggacaacg tccttgacat caccagtaat cacaccacct tggatagccg cacccatagc
    15301 aactacttca tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc
    15361 ttcaacaacg gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga
    15421 caagctcaaa cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag
    15481 gtcacgagtc aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc
    15541 agcctcacct gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc
    15601 tttcttcgct ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa
    15661 gtcgataccg ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa
    15721 gtcgtcacca ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc
    15781 caattcaagg atagagacgt cgaatgtacc accaccaagg tcaaatacca agattttttc
    15841 ttctttgtca gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat
    15901 acgttctact tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc
    15961 gttgaagtaa gccggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc
    16021 agcgtagcct ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt
    16081 tccatttgca gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc
    16141 tgggtttgta actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa
    16201 tgagactaca gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt
    16261 tccttcaaga actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga
    16321 catgtgtttt tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt
    16381 ggcgacgccg tcagagcttg acttcgtcaa tctctttgac taaactttga gcctaaggtc
    16441 tcaaaatttg cgcaaatagc accacggcga agagtatcgt ctttggttcg cttcgctcac
    16501 tattacaaag ccaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt
    16561 ttctattatg taaattgcga cacgaggagt cgaaatcgat tttatttcga cgacgagtta
    16621 gtaaggaagc taggcaaacg tcatagcgat tgccgttttc tgacgagttg ctttagctac
    16681 cgtcagaatt gccgaatcga acacgcccta agctctgagt aaaaaagata gattttcttg
    16741 tgttcatcga acacttcgtc aatctcctat ttttactgcg agctttttac gagctttgta
    16801 tcttagttat acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct
    16861 ttttgaaaga cttgggcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg
    16921 atggccatat ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct
    16981 tctttcaaag cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct
    17041 gtcaaacctt caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt
    17101 gccaagtcct ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg
    17161 atattttgca tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca
    17221 tttgccaagt ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc
    17281 tcttcttgaa cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt
    17341 aatgatttca atcttaatgt acttcgtaat gattactgct gaggtagcgg taaaaatctg
    17401 tcaacttcat ggtcaaaaca cggttgacca cattgacttg attgattagc tgttggtaat
    17461 ccagattaac tggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact
    17521 tactactaat caccgctagg tcagctaaac aggactcttg accgtctgca acacgaacat
    17581 tttgcatctg atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt
    17641 caaagaactg ataggcttct agattggcaa aattcaagag attgaccttg cccgccatca
    17701 caatgttttc gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg acattatccg
    17761 ttgttgtaaa gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat
    17821 ctaaaacggt gtgaccgagg aaacgttcct gaatgatgct cttcagtttc agcaaatcct
    17881 cctgcaagaa gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg
    17941 taaataccgc caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaacgtt
    18001 gcctgctcgg ctcaacatcc agtgccacta ccgtacagcc actcaggcct gttagcaagt
    18061 tagcagcctc ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa
    18121 tctcatatac ctcattttca gccagccggt gaaaatccag tgagtgtttc acatagtact
    18181 gaaaaccagc aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt
    18241 gtttttctag ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt
    18301 gcaaggcttt tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta
    18361 aaatatcctg ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca
    18421 ctcaatgcat ccaagtgcta acttatgatt ctattataca cccttaaaag agaatgtcaa
    18481 gacaaaaact caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac
    18541 ctagaacctt gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt
    18601 agataagaaa tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagatcc
    18661 tctctaaaca aactcgtaca aacaacaaga ccacctaaga aagtagttgt acaggaacga
    18721 agtctagatc gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga
    18781 agtaaatcag aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa
    18841 cctctatctc taaaatcttg cagttcatgc ttatattttt taagaaatct agaatcatag
    18901 atacggtaga tgacatcgtc tggttgacat tggtcaaaat agaacaaacc aaaacgactc
    18961 gttctatacc tccaaccttt caaatgcatc tcatgtaaat attcttcttc cttgtccaaa
    19021 tcaacaatgg tgaaaatccg aaattctact ctgctattca ttgtcttacc ccaaaattag
    19081 aaaacatgcc tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa
    19141 aatataagaa atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa
    19201 aaacactttc caactgaaag aactacctcc agtgacaaac tttgagcaaa acggtagtag
    19261 agctaaaaag agaagtaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa
    19321 aaatctttat ttaaactaaa atattatagc aaaatttacg ccagtttttg aacggctgat
    19381 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    19441 accagcccga ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacagcggaa
    19501 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    19561 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    19621 tagtttattt tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt
    19681 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    19741 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    19801 ggtcgaattg aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    19861 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    19921 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    19981 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    20041 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    20101 aaaggattga cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    20161 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    20221 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacagggaa aacgttcatg
    20281 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    20341 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaagcc attcgaaaag
    20401 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttctttcgaa
    20461 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    20521 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    20581 aaggaaaaca gtaactggcg taaggtaatt gattatttca gttctgcgac acagattggg
    20641 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtaagcca
    20701 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    20761 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    20821 gctaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    20881 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac
    20941 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    21001 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    21061 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    21121 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    21181 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    21241 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    21301 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    21361 ctggaaacag gtgcgaaaac agtcagtggt tctacgcctg gtttcgtagg tgaggaaggt
    21421 gacccagtag aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    21481 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcgaaag
    21541 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcagat
    21601 aagaaacatt atgggaagtt tgctgatgga agcactcaag aaattgatgt tccttatgat
    21661 attcctgata cttgggagtg ggtgaggttt tctacattgg ttgaaattgt cagaggtggc
    21721 tctccacgac caatcaaaga ttatcttact tctgaagtag atggaataaa ttggataaaa
    21781 ataggtgata ctgaaaaggg tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa
    21841 tcagggctta acaaaactag atttgtaaaa aaaggtacat ttttgttaac taattctatg
    21901 agttttggta gaccttatat tttgaatgtt gatggtgcaa tacacgatgg atggttggct
    21961 atttcgaact atgaaaactc attaaataaa gattacctat tctatattct ttcatcaaat
    22021 gtagtttatt ctcaatttct atctctaatt agtggagctg ttgtgaaaaa cttgaatagt
    22081 gataaagttg cttctattct tatc
//
LOCUS       DAVBED010000035        22017 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBED010000035 DAVBED010000000
VERSION     DAVBED010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.035"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQ547_001347"
     CDS             51..233
                     /locus_tag="VQ547_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2543190.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQ547_001348"
     CDS             533..1372
                     /locus_tag="VQ547_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2543191.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQ547_001349"
     CDS             1390..3228
                     /locus_tag="VQ547_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2543192.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQ547_001350"
     CDS             3241..4656
                     /locus_tag="VQ547_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2543193.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQ547_001351"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQ547_001351"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2543194.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQ547_001352"
     CDS             6294..6803
                     /locus_tag="VQ547_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543195.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQ547_001353"
     CDS             6880..9285
                     /locus_tag="VQ547_001353"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2543196.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQ547_001354"
     CDS             complement(9458..10459)
                     /locus_tag="VQ547_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2543197.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQ547_001355"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQ547_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQ547_001356"
     CDS             11187..11453
                     /locus_tag="VQ547_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543198.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQ547_001357"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQ547_001357"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2543199.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQ547_001358"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQ547_001358"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2543200.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQ547_001359"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQ547_001359"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2543201.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQ547_001360"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQ547_001360"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2543202.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQ547_001361"
     CDS             18436..19320
                     /locus_tag="VQ547_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543203.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQ547_001362"
     CDS             19402..20745
                     /locus_tag="VQ547_001362"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2543204.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQ547_001363"
     CDS             20738..21124
                     /locus_tag="VQ547_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2543205.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQ547_001364"
     CDS             21128..22012
                     /locus_tag="VQ547_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2543206.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6764 a         3965 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVBED010000036        21460 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBED010000036 DAVBED010000000
VERSION     DAVBED010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.036"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQ547_001365"
     CDS             66..287
                     /locus_tag="VQ547_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543207.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQ547_001366"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQ547_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQ547_001367"
     CDS             1187..2416
                     /locus_tag="VQ547_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2543208.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQ547_001368"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQ547_001368"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2543209.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQ547_001369"
     CDS             5545..6549
                     /locus_tag="VQ547_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2543210.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQ547_001370"
     CDS             6618..7484
                     /locus_tag="VQ547_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543211.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQ547_001371"
     CDS             7481..8239
                     /locus_tag="VQ547_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543212.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ547_001372"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ547_001372"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2543213.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ547_001373"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ547_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2543214.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQ547_001374"
     CDS             11215..11544
                     /locus_tag="VQ547_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2543215.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ547_001375"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ547_001375"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2543216.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQ547_001376"
     CDS             12718..14043
                     /locus_tag="VQ547_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2543217.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQ547_001377"
     CDS             14074..14250
                     /locus_tag="VQ547_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2543218.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQ547_001378"
     CDS             14309..14443
                     /locus_tag="VQ547_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2543219.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQ547_001379"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQ547_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2543220.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQ547_001380"
     CDS             15827..15985
                     /locus_tag="VQ547_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543221.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQ547_001381"
     CDS             17035..18294
                     /locus_tag="VQ547_001381"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2543222.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQ547_001382"
     CDS             18310..18861
                     /locus_tag="VQ547_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543223.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQ547_001383"
     CDS             18854..20131
                     /locus_tag="VQ547_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2543224.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQ547_001384"
     CDS             20147..21007
                     /locus_tag="VQ547_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2543225.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQ547_001385"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQ547_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6560 a         3687 c         4816 g         6397 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taactgatgc
    21421 acgatttaag cgtcttgttg gtgttcaacg cacgactttt
//
LOCUS       DAVBED010000037        21310 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBED010000037 DAVBED010000000
VERSION     DAVBED010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.037"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            40..384
                     /locus_tag="VQ547_001386"
     CDS             40..384
                     /locus_tag="VQ547_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543226.1"
                     /translation="MIAHTIHQKFNLKVPNYRQEEDWARMGLPIIRKEISNWHIKTSQ
                     YYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKAEKQGITLYHHV
                     LIDLFISYFNPL"
     gene            complement(581..1501)
                     /gene="cysK"
                     /locus_tag="VQ547_001387"
     CDS             complement(581..1501)
                     /gene="cysK"
                     /locus_tag="VQ547_001387"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2543227.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1786..2421)
                     /locus_tag="VQ547_001388"
     CDS             complement(1786..2421)
                     /locus_tag="VQ547_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2543228.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            2477..3775
                     /locus_tag="VQ547_001389"
     CDS             2477..3775
                     /locus_tag="VQ547_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2543229.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3772..4434
                     /locus_tag="VQ547_001390"
     CDS             3772..4434
                     /locus_tag="VQ547_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2543230.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4514..5062
                     /gene="raiA"
                     /locus_tag="VQ547_001391"
     CDS             4514..5062
                     /gene="raiA"
                     /locus_tag="VQ547_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2543231.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5198..7171
                     /locus_tag="VQ547_001392"
     CDS             5198..7171
                     /locus_tag="VQ547_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2543232.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7168..7620
                     /gene="rplI"
                     /locus_tag="VQ547_001393"
     CDS             7168..7620
                     /gene="rplI"
                     /locus_tag="VQ547_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2543233.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7664..9016
                     /gene="dnaB"
                     /locus_tag="VQ547_001394"
     CDS             7664..9016
                     /gene="dnaB"
                     /locus_tag="VQ547_001394"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2543234.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9018..9284
                     /locus_tag="VQ547_001395"
     CDS             9018..9284
                     /locus_tag="VQ547_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543235.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9373..10719
                     /gene="cbpD"
                     /locus_tag="VQ547_001396"
     CDS             9373..10719
                     /gene="cbpD"
                     /locus_tag="VQ547_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2543236.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10802..10904
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10975..11265
                     /locus_tag="VQ547_001397"
     CDS             10975..11265
                     /locus_tag="VQ547_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2543237.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11228..11986
                     /locus_tag="VQ547_001398"
     CDS             11228..11986
                     /locus_tag="VQ547_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543238.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            12024..13031
                     /locus_tag="VQ547_001399"
     CDS             12024..13031
                     /locus_tag="VQ547_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2543239.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13031..13759
                     /locus_tag="VQ547_001400"
     CDS             13031..13759
                     /locus_tag="VQ547_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543240.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13878..14336
                     /locus_tag="VQ547_001401"
     CDS             13878..14336
                     /locus_tag="VQ547_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2543241.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14338..16770
                     /locus_tag="VQ547_001402"
     CDS             14338..16770
                     /locus_tag="VQ547_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2543242.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17412..18065
                     /gene="rr06"
                     /locus_tag="VQ547_001403"
     CDS             17412..18065
                     /gene="rr06"
                     /locus_tag="VQ547_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2543243.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18062..19402
                     /gene="hk06"
                     /locus_tag="VQ547_001404"
     CDS             18062..19402
                     /gene="hk06"
                     /locus_tag="VQ547_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2543244.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19485..20012
                     /locus_tag="VQ547_001405"
     CDS             19485..20012
                     /locus_tag="VQ547_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2543245.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20091..>21310
                     /locus_tag="VQ547_001406"
     CDS             20091..>21310
                     /locus_tag="VQ547_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2543246.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT         6688 a         3546 c         4808 g         6268 t
ORIGIN      
        1 cctaaagccc ctttagcgca taactttggc tcagcttcta ttatcgctca caccatccat
       61 cagaagttta atctgaaggt acccaattat cgccaagaag aagattgggc taggatgggt
      121 ttaccaatca tacgtaagga aatctctaat tggcatatca agacgagtca atactatttg
      181 gagccccttt ataacctctt gcgagagaga ctattgactc agcccttact tcatgcggat
      241 gaaacttctt atagggtgct agagagtgat agtcagctga cttactactg gacttttttg
      301 tctgggaaag ctgagaaaca agggattacg ctttaccatc atgtcctaat cgatttgttc
      361 atatcttatt tcaatccatt ataaatagtg agaaatatct atcctatctt ctagaatgtc
      421 ttccaaacgt ggaaactctc gtaaacaaag aggttttaga ggcctattta ccatggacta
      481 aagttgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc cgtgagttct
      541 ctagtctgga gatttttcaa tagacttcgt tattggacgg ttacaattca taaagtgctg
      601 tagagagata acgttcaccg ttatctggtg ctagggcaag gactttttta cctgtaccta
      661 attttttggc aacctcgatg gctccgtaga tagctgcagc tgaggaaatc cctacaagga
      721 agccttcttt tccaccaatt tcacgtccga gtgcaagagc gtcatctgat gttacacgaa
      781 cgataccatc ataggcttta gtatcaagtg tatcaggaat aaatccagct gagatacctt
      841 gaattttgtg aggaccaggt ttttcaccag atagaatagc agattcatct gcttctactg
      901 caaaaacttg aatgttagaa ttttctgatt tgagtgcatg agaaacacca gaaatcgttc
      961 caccagtacc tactccagca acaaaggcat ctaatccatc tttaccgaaa gcagctagta
     1021 tctcagctcc tgttgttctt tcgtgtactt ctggattagc tggattgtca aattgaagag
     1081 gaaggaaacc atcacgttca gcagcgattt cttgagcctt agcaatagca cctttcattc
     1141 cctcgctacc aggagttagg acgagttcag caccataagc ttggataatt ttacgtcgtt
     1201 ctacactcat agtttcaggc ataacgatga cgactttata ccctttagca gcacctaccc
     1261 atgaaagtcc aataccggtg tttccacttg ttgcttcaac aatagtagaa ccaagtttca
     1321 gaataccatc ttgttcagct ttttcaatca tgctaagggc aatacggtct tttacagatg
     1381 aaccaggatt aaatgcttca agctttatat agacgtctgc agcaccttct ggcacgatgt
     1441 tgttaagttt aacaatcggt gtttgaccga ttaattcagt aatgttgtta taaatagaca
     1501 tatgaatacc tctttgtata agatatcttt agtataacgc tatccatacc atttgtaaaa
     1561 tatagaaatc ctatcgaagc gataggattt ctatatatca tagatcaaag tcattaattt
     1621 tcaagtgatt gcgttcagtt aattctagta aataggtgtg aaggaaaacg atatcaggtt
     1681 tcgtttgaat tgcttcattt tctagtatat tttggtacgc atctttttat tttgctcgct
     1741 aaagtagttg tgagaatgtc aacgaaacgc tgtattattc attgtttaca ctaagtttac
     1801 agaaacttca acctctcgta aaccttggtc agttaaagtg acttttccat taaaaaactc
     1861 cacaagtgca gctttaatag tttctttttc ttctttatca acataaatca tcgtatcgac
     1921 ttgatctgta aagtttgtat ccagctccat gagatcatgt tctttaagga agttactgta
     1981 ctcttggtac tgagcataag acatttgaat agcaatgcca gcctgttctt ttatttcaat
     2041 aataccaatt tctttgacag ctaaggcgac actgccggcg taagcacgaa ttagtcctcc
     2101 agcgcctagt ttaataccac caaagtagcg tgtcacgacc acacagacat tggtgagatt
     2161 gtgattttct agtaccccaa gcatgggaac accagcagta ccactaggct caccatcatc
     2221 acttgtacgt ttaatttcac tacgttctcc aataataaag gcagagcagt tatgtgtcgc
     2281 tttgtagtgt tcttttttga tggcagtaat gaagtcacga gcctcttctt cgctataaac
     2341 acgcttggca tggcagataa agcgagattt tttgatttct tcttggactt ggccgtcctc
     2401 tttaattgtc ctaaattcca tgatttaatt gtactaaaaa ataatctaaa gtgctagttt
     2461 ttacgaataa agaagtatga aagtaaattt agattatctc ggtcgtttat ttactgagaa
     2521 tgaattaaca gaagaagaac gtcagttggc ggagaaactt ccagcaatga gaaaggagaa
     2581 ggggaaactt ttctgtcaac gttgtaatag tactattcta gaagaatggt atttgcccat
     2641 cggtgcttac tattgtcgag agtgcttgct gatgaagcga gtcagaagtg atcaaacttt
     2701 atactatttt ccgcaggagg attttccgaa gcaagatgtt ctcaaatggc gcggccaatt
     2761 aactcctttt caagagaagg tgtcagaggg actgcttcaa gcagtagaca agcaaaagcc
     2821 aaccttagtt catgcggtaa caggagctgg aaagacagaa atgatttatc aagtagtggc
     2881 taaagtgatc aatgcgggtg gtgcagtgtg tttggctagt cctcgcatag atgtttgttt
     2941 ggagctgtac aagcgcctgc aacaggattt ttcttgcggt atagctttgc tacatggaga
     3001 atcggaacct tattttcgaa caccactagt tgttgcaaca acccatcagt tattgaagtt
     3061 ttatcaagct tttgatttgc tgatagtgga tgaagtagat gcttttcctt atgttgataa
     3121 tcccacgctt taccacgctg tcaagaatag tgtaaaggag aatggattga gaatcttttt
     3181 aacagcgact tcgaccaatg agttagataa aaaggtccgt ttaggagaac taaaaagact
     3241 gagtttaccg agacggtttc atggaaatcc gttgattatt ccaaaaccaa tttggttatc
     3301 ggattttaat cgctacttag acaagaatcg tttgtcacca aagttaaagt cctatattga
     3361 gaagcagaga aagacagctt atccgttact catttttgct tcagaaatta agaaagggga
     3421 gcagttagaa gaaatcttac aggagcaatt tccaaatgag aaaattggct ttgtatcttc
     3481 tgtaacagag gatcgattag agcaagtaca agcttttcga gatggagaac tgacaatact
     3541 tatcagtacg acaatcttgg agcgtggagt taccttccct tgtgtggatg ttttcgtaat
     3601 agaggccaat catcgtttgt ttaccaagtc tagtttgatt cagattggtg gacgagttgg
     3661 acgaagcatg gatagaccga caggagattt gcttttcttc catgatgggt taaatgcttc
     3721 aatcaagaag gcgattaagg aaattcagat gatgaataag gaggctggtc tatgaagtgc
     3781 ttgttatgtg ggcagactat gaagactgtt ttaactttta gtagtctctt acttctgagg
     3841 aatgatgact cttgtctttg ttcagactgt gattctactt ttgaaagaat tggggaagag
     3901 aactgtccaa attgtatgaa aacagagttg tcaacaaagt gtcaagcttg tcaattttgg
     3961 tgtaaagaag gagttgaagt cagtcataga gcgattttta cttacaatca agctatgaag
     4021 gattttttca gtcggtataa gtttgatgga gacttcctgt taagaaaagt tttcgcttca
     4081 tttttaagtg aggagttgaa aaagtacaaa gagtatcaat ttgttgtaat tcccctaagt
     4141 cctgatagat atgctaacag aggatttaat caggttgagg gcttggtaga ggcagcaggc
     4201 tttgagtatc tagatttatt agagaaaaga gaagagagag ccagttcttc taaaaatcgt
     4261 tcagagcgct tggggacaga acttcctttc tttattaaaa gtggagtcac tattcctaaa
     4321 aaaatcctac ttatagatga tatctatact acaggagcaa ctataaatcg tgttaagaaa
     4381 ctgttggaag aagctggtgc taaggatgta aaaacatttt cccttgtaag atgaggaaaa
     4441 aatttgcaaa aatagaatga aagcgttata ataaaatcat aaaaacaaaa atgtttagaa
     4501 agaaggtact catatgatta aatatagtat ccgtggtgaa aacctagaag taacagaagc
     4561 aattcgtgat tatgtagttt ctaaactcga aaagatcgaa aagtacttcc aaccagaaca
     4621 agagttggat gcccgaatta acttaaaagt ttatcgtgaa aaaacggcta aagtggaagt
     4681 aacgattccg cttggatcta ttactctccg cgcagaagat gtatctcaag atatgtatgg
     4741 ttcaattgac cttgtaactg ataaaattga acgtcagatt cgtaaaaata aaacaaaaat
     4801 cgagcgtaaa aataaaaata aggtagcaac tggtcaatta tttacagatg ctttggtgga
     4861 agattcaaat attgtccagt ctaaagttgt tcgttcaaaa caaattgatt taaaaccaat
     4921 ggatttggaa gaagcaattc tacaaatgga tttattgggg catgatttct ttatctatgt
     4981 ggatgttgaa gatcagacaa ccaatgtgat ttatcgtcgt gaggatggcg aaattggttt
     5041 gttagaggtt aaagaatctt aatttcaata tgtgtaaagg taggtttact gaattgtaaa
     5101 ctaccttttt cttataattg atagaattac tgattacact tttaaaaagt cgctttttga
     5161 ggggtattat ggtataatgg gtgccaagag gttttgaatg aaaaaatttt atgtaagtcc
     5221 aatttttcct attctagtag gattgattgc gtttggagtc ttatccactt tcattatttt
     5281 tgttaataat aatctgttga cggttttaat tttgtttctt tttgtaggag gctatgtttt
     5341 tttatttaag aaactgagag tgcattatac aaggagtgat gtagaacaga tacagtatgt
     5401 aaaccaccaa gcggaagaaa gtttgacagc tctattggaa cagatgcctg taggtgttat
     5461 gaaattgaat ttatcttctg gagaggttga gtggtttaat ccctatgctg aattgatttt
     5521 gaccaaggaa gatggtgatt ttgatttaga agctgttcaa acgattatca aggcttcagt
     5581 aggaaatccg tctacttatg ccaagcttgg tgagaagcgt tatgctgttc atatggatgc
     5641 ttcttccggt gttttgtatt ttgtagatgt atccagggaa caagccataa cagatgaatt
     5701 ggtaacaagt cgaccagtga ttgggattgt ctctgtggat aattatgatg atttggagga
     5761 tgcaacttct gagtcagata ttagtcaaat caatagtttt gtagctaatt ttatatcaga
     5821 gttttcagaa aaatacatga tgttttctcg tcgggtaagt atggatcgat tttatctatt
     5881 tactgactac acggtgcttg agggcttgat gaatgataaa ttttctgtta ttgatgcttt
     5941 cagagaagag tcgaaacaga gacagttgcc cttgacctta agtatgggat tttcttatgg
     6001 cgatggaaat catgatgaga tagggaaagt tgctttgctc aatttgaact tggctgaagt
     6061 acgtggtggc gaccaggtgg ttgttaagga aaacgacgaa acgaaaaatc cagtttattt
     6121 tggtggtggg tctgctgctt caatcaagcg tacacggact cgtacgcgcg ctatgatgac
     6181 agctatttca gataagattc ggagtgtaga tcaggttttt gtagtcggtc acaaaaattt
     6241 agacatggat gctttgggct ctgctgtagg tatgcagttg ttcgccagca atgtgattga
     6301 aaatagctat gctctttatg atgaagaaca aatgtctcca gatattgaac gagctgtttc
     6361 attcatagaa aaagaaggag ttacgaagtt gttgtctgtt aaggatgcat tggggatggt
     6421 gaccaatcgt tctttgttga ttcttgtaga ccattcaaag acagccttaa cattatcaaa
     6481 agaattttat gatttattta cccaaaccat tgttattgac caccatagaa gggatcagga
     6541 ttttccagat aatacggtca ttacttatat cgaaagtggt gcaagtagtg ccagtgagtt
     6601 ggtaacggaa ttgattcagt tccagaattc taagaaaaat cgtttgagtc gtatgcaagc
     6661 aagtgtcttg atggctggta tgatgttgga tactaaaaat ttcacctcgc gagtaactag
     6721 tcggacattt gatgttgcta gctatctcag aacgcgcgga agtgatagta ttgctatcca
     6781 ggaaatcgct gcgacagatt ttgaagaata tcgtgaggtc aatgaactta ttttacaggg
     6841 gcgtaaatta ggttcagatg tactaatagc agaggctaag gacacgaaat gctatgatac
     6901 agttgttatt agtaaggcag cagatgccat gttagccatg tcaggtattg aagcgagttt
     6961 tgttcttgcg aagaatacac aaggatttat ctctatctca gctcgaagtc gtagtaaact
     7021 gaatgtacaa cggattatgg aagagttagg cggtggaggc cactttaatt tggcagcagc
     7081 tcaaattaaa gatgtaacct tgtcagaagc aggtgaaaaa ctgacagaaa ttgtattaaa
     7141 tgaaataaag gaaaaggaga aagaagaatg aaagtaatct ttttagcaga tgttaaagga
     7201 aaaggtaaaa aaggcgaaat taaggaagta ccaacagggt atgcgcaaaa ctttcttatc
     7261 aaaaagaatc tagccaaaga agcgactgct caagctgtag gtgaacttcg tggtaaacaa
     7321 aaatcggaag aaaaagctca cgctgagatg attgcagaag gaaaagcaat taaagcacaa
     7381 cttgaagcag aagaaactgt tgtagaattt gttgaaaaag ttggtccaga tggtcgtacc
     7441 tttggctcta ttaccaataa gaagattgca gaagaattgc aaaaacaatt tggaattaag
     7501 attgataaac gtcatattca agtacaagct ccgattcgag cggttggttt gattgatgtg
     7561 ccagtgaaaa tctatcaaga tatcacaagt gtaatcaatc ttcgtgtgaa agaaggataa
     7621 gtttacacct tcttgacaag attgtaaaag gaagggaagt ctgatggcag aagtagaaga
     7681 gttacgagta caacctcaag atatcttagc tgagcaatcc gttttagggg ctatctttat
     7741 tgatgagagt aaacttgttt ttgtgcgaga atacattgag tctcgggact tttttaagta
     7801 tgcccatcgt ttgattttcc aagccatggt cgatttatcc gatcgtggtg atgccataga
     7861 tgcaacaacg gttcgtacta tccttgataa tcaaggtgat ttacagaata ttggtggctt
     7921 gtcttacttg gttgagattg ttaattctgt gccaacttct gctaatgcgg agtattatgc
     7981 taagattgtt gcagaaaaag caatgctacg tcgtttaatt gccaagttga cagagtctgt
     8041 caaccaagct tacgaagcgt cacaaccagc tgatgaaatt attgctcagg cagaaaaagg
     8101 gctgattgat gtcagtgaaa atgcaaatcg aagcgggttt aagaacattc gagatgtgtt
     8161 gaatctcaac tttggaaatc tggaagctcg ctcgcaacaa acgaccgata ttacaggtat
     8221 tgcgacaggt tatcgtgatt tggatcatat gacaacagga cttcatgagg aggagttgat
     8281 tatcttagca gctcgtccag cagttggtaa gacagcattt gccttgaata tcgctcagaa
     8341 cattgggact aagttggaca aaacggttgc tattttttca ctcgaaatgg gtgcggaaag
     8401 cttggtagat cgtatgttag ctgcagaagg cttagtggag tcacattcta tccgtacagg
     8461 gcaattgaca gatgaggagt ggcaaaaata tactattgct cagggtaatc tagctaacgc
     8521 cagtatctat atcgatgata cgccaggtat tcggattaca gagattcgtt ctcgttctcg
     8581 taaattggct caagaaactg gaaatcttgg tttgattttg atagactatt tgcaacttat
     8641 cacgggaact ggtcgagaaa atcgtcaaca agaagtttct gaaatttctc gtcagttgaa
     8701 aatactagcc aaggaattga aggttccagt aatcgctctg agtcagcttt ctcgtggtgt
     8761 agaacaacgt caggacaaga gaccggtctt gtctgatatt cgtgaatctg ggtctattga
     8821 gcaggacgct gatatcgtag cttttctcta tcgcgatgac tactatgaac gtggtggtga
     8881 agaagaggag ggtatcccaa ataataaggt ggaagttatt atcgagaaaa accgtagtgg
     8941 agctcgtgga acagtggaat tgattttcca aaaagaatac aataaatttt caagtatctc
     9001 aaagagggag gcataagatg tcagatgcat ttacagatgt agccaagatg aaaaaaatca
     9061 aagaagaaat caaggcacat gagggacaag tcgtagaaat gactttggag aatggtcgta
     9121 agcgccaaaa aaatagattg ggtaagctaa ttgaagttta tccatctcta tttattgtgg
     9181 agtttgggga tgtggaagga gataaacaag ttaatgttta cgttgaatcc tttacttact
     9241 cagatattct tacagaaaag aatttgattc attatcttga ctaaagtgag aaattttctc
     9301 actttttctt ttttctccga ataatttagg tgaaggcaat catcgcttta tattattttt
     9361 caaggaggaa gaatgaaaat tttaccgttt atagcaagag gaacaagtta ttacttgaag
     9421 atgtcagtta aaaagcttgt tcctttttta gtagtaggat tgatgctagc agctggtgat
     9481 agtgtctatg cctattccag aggaaatgga tcgattgcgc gtggggatga ttatcctgct
     9541 tattataaaa atgggagcca ggagattgat cagtggcgca tgtattctcg tcagtgtact
     9601 tcttttgtag cctttcgttt gagtaatgtc aatggttttg aaattccggc agcttatgga
     9661 aatgcgaatg aatggggaca tcgtgctcgt cgggaaggtt atcgtgtaga taatacaccg
     9721 acgattggtt ccattacttg gtctactgca ggaacttatg gtcatgttgc ctgggtgtca
     9781 aatgtaatgg gagatcagat tgagattgag gaatataact atggttatac agaatcctat
     9841 aataaacgag ttataaaagc aaacacgatg acaggattta ttcattttaa agatttggat
     9901 ggtggcagtg ttgggaatag tcaatcctca acttcaacag gcggaactca ttattttaag
     9961 accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga ttactattat
    10021 cctggagaga aggttcatta tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt
    10081 tatactgcct ataatggaag ctatcgttat gttcaattgg aggctgtgaa taaaaatcct
    10141 ctaggtaatt ctgttctttc ttcaacaggt ggaactcatt attttaagac caagtctgct
    10201 atcaaaactg aacccctagt tagcggaact gtgattgatt actattatcc tggggagaag
    10261 gttcattatg atcagatact tgaaaaagac ggctacaagt ggttgagtta tactgcctat
    10321 aatggaagtc gtcgctatat acagctagag ggagtgactt cttcacaaaa ttatcagaat
    10381 caatcaggaa atatctctag ctatggatcc aataatagtt caactgtcgg ttggaagaaa
    10441 ataaatggta gttggtatca tttcaaatca aatggttcta aatcaacagg atggctgaaa
    10501 gacggttcta gctggtatta tttgaaatta tctggtgaaa tgcagacagg atggttaaag
    10561 gagaatggct cgtggtatta tctgggtagt tcaggggcaa tgaaaacagg ctggtaccag
    10621 gtctctggta agtggtatta ttcttactct tcaggcgcct tagctgttaa tacgacggtg
    10681 gatggctaca gagtaaacag tgatggagaa cgagtataga aaattggagt aggagaaatt
    10741 tcctgctctt ttctgtaagc agtttccttg acatttttct tattttgcgc tatcatatat
    10801 acatataata tatgggagtc tgtgtacagt ctgagaggaa gtgttaaact tcgaccgcac
    10861 ctgatctggg taatgccagc ggagggaacg atacttagtc taattttgca ccttttccat
    10921 gtatggtaaa ggtttttctt ttttttaaaa ggaaaacgag aagaggaggt tcttatgaaa
    10981 gcaagcattg ccttgcaagt tttaccccta gcacagggga ttgatcggat agctgttatt
    11041 gatcaggtca ttgcttatct gcaaactcaa gaagtgacga tggtagtgac accatttgaa
    11101 acggtcttgg aaggggagtt tgatgagctt atgcgcattc taaaagaagc gctggaagtg
    11161 gcagggcagg aggcagacaa tgtctttgcc aatgtcaaaa taaatgtagg agagatttta
    11221 agtattgatg agaaacttga aaagtatact gagacgacac attagtctat tgggctttct
    11281 cggagtattg tcaatctggc agttagcagg ttttcttaaa cttctcccca agtttatcct
    11341 gccgacacct cttgaaattc tccagccctt tgttcgtgac agagaatttc tctggcacca
    11401 tagctgggcg accttgagag tggctttact ggggctgatt ttgggagttt tgattgcctg
    11461 tcttatggct gtgctcatgg atagtttgac ttggctcaat gacctgattt accctatgat
    11521 ggtggtcatt cagaccattc cgaccattgc catagctcct atcctggtct tgtggctggg
    11581 ttatgggatt ttgcccaaga ttgtcttgat tatcttaaca acaacctttc ccatcatcgt
    11641 tagtattttg gacggtttta ggcattgtga caaggatatg ctgactttgt ttagtctgat
    11701 gcgagcaaac ccttggcaaa tcctgtggca ttttaaaatc ccggttagcc tgccttactt
    11761 ttatgcaggt ctgagggtca gtgtctccta cgcctttatc acaactgtgg tatctgagtg
    11821 gttgggaggt tttgaaggtc ttggtgttta tatgattcag tctaaaaaac tgtttcagta
    11881 tgataccatg tttgccatta ttattctggt gtcgattatc agtcttttgg gtatgaagct
    11941 ggtcgatatc agtgaaaaat atgtgattaa atggaaacgt acttaaaata gagcgttttt
    12001 gaaaaagaaa agaggaaatc aaaatgaaga aaacatggaa agtgttttta acgcttgtaa
    12061 cagctcttgt agctgttgtg cttgtggcct gtggtcaagg aactgcttct aaagacaaca
    12121 aagaggcaga acttaagaag gttgacttta tcctagactg gacaccaaat accaaccaca
    12181 cagggcttta tgttgccaag gaaaaaggtt atttcaaaga agctggagtg gatgttgatt
    12241 tgaaattgcc accagaagaa agttcttctg acttggttat caacggaaag gcaccatttg
    12301 cagtgtattt ccaagactac atggctaaga aattggaaaa aggagcagga atcactgccg
    12361 ttgcagctat tgttgaacac aatacatcag gaatcatctc tcgtaaatct gataatgtaa
    12421 gcagtccaaa agacttggtt ggtaagaaat atgggacatg gaatgaccca actgaacttg
    12481 ctatgttgaa aaccttggta gaatctcaag gtggagactt tgagaaggtt gaaaaagtac
    12541 caaataacga ctcaaactca atcacaccga ttgccaatgg cgtctttgat actgcttgga
    12601 tttactacgg ttgggatggt atccttgcta aatctcaagg tgtagatgct aacttcatgt
    12661 acttgaaaga ctatgtcaag gagtttgact actattcacc agttatcatc gcaaacaacg
    12721 actatctgaa agataacaaa gaagaagctc gcaaagtcat ccaagccatc aaaaaaggct
    12781 accaatatgc catggaacat ccagaagaag ctgcagatat tctcatcaag aatgcacctg
    12841 aactcaagga aaaacgtgac tttgtcatcg aatctcaaaa atacttgtca aaagaatacg
    12901 caagcgacaa ggaaaaatgg ggtcaatttg acgcagctcg ctggaatgct ttctataaat
    12961 gggataaaga aaatggtatc cttaaagaag acttgacaga caaaggcttc accaacgaat
    13021 ttgtgaaata atgacagaaa ttagactaga gcatgtcagt tatgcctatg gtcaggagag
    13081 gattttagag gatatcaacc tacaggtgac ttcaggcgaa gtggtttcca ttctaggccc
    13141 aagtggtgtt ggaaagacca ccctctttaa tctaatcgct gggattttag aagttcagtc
    13201 agggagaatt gtccttgatg gtgaagaaaa tcccaagggg cgcgtgagtt atatgttgca
    13261 aaaggatctg ctcttggagc acaagacggt gcttggaaat atcattctgc ccctcttgat
    13321 tcaaaaggtg gataaggcag aagctatttc ccgagcggat aaaattcttg cgaccttcca
    13381 gctgacagct gtaagagaca agtatcctca tgaacttagc ggtgggatgc gccagcgtgt
    13441 agccttactc cggacctacc tttttgggca caagctcttt ctcttagatg aggcctttag
    13501 cgccttggat gagatgacaa agatggaact ccacgcttgg tatcttgaga ttcacaaaca
    13561 gttgcagcta acaaccctga tcatcacgca tagtattgag gaggccctca atctcagcga
    13621 ccgtatctat atcttgaaaa atcgccctgg gcagattgtt tcagaaatta aactagattg
    13681 gtctgaagat gaggacaagg aagtccaaaa gattgcctac aaacgtcaaa tcttggcaga
    13741 attaggctta gataagtaga aaaataggga gttggtgaag attatccttt accagcgccc
    13801 tttttctttt aaaaatgaga aaatttcggt ataatagtca aacaaggtca aggtttaaag
    13861 agagaggtgg gtttgttatg agatttaaaa atacatcgga tcatattgag gcctacatca
    13921 aggcgatttt agatcaatct ggtatcgtgg agttgcaacg gagtcagttg gcagatacct
    13981 ttcaggttgt tcctagtcag attaactacg tgatcaagac acgctttacg gaaagtagag
    14041 gctacttggt tgaaagtaag cgtggtggcg gaggctacat tcgtatagga cggattgagt
    14101 tttctagtca tcatgaaatg ctccgggagc tgctttactc gattggtgag cgagtcagtc
    14161 aagaaattta tgaggatatt ctccagcttt tggttgagca ggaattgatg accaagcagg
    14221 agatgaattt gctagaatca gtagctttgg atcgcgtttt aggagaagaa gctccagttg
    14281 ttcgagcaaa catgctacgt caggtcatac aagaggtaga tagaaaaggg aagtaagatg
    14341 aactattcaa aagcattgaa tgaatgtatc gaaagtgcct acatggttgc tggacatttt
    14401 ggagctcgtt atctagagtc gtggcacttg ttgattgcca tgtctaatca cagttatagt
    14461 gtagcagggg caactttaaa tgattatccg tatgagatgg accgtttaga agaggtggct
    14521 ttggaactga ctgaaacgga ctatagccag gatgaaacct ttatggaatt gccgttctcc
    14581 cgtcgtttgc aggttctttt tgatgaagca gagtatgtag cgtcagtggt ccatgctaag
    14641 gtactaggga cagagcacgt cctctatgcg attttgcatg atggcaatgc cttggcgact
    14701 cgtatcttgg agagggctgg tttttcttat gaagacaaga aagatcaggt caagattgct
    14761 gctcttcgtc gaaatttaga agaacgggca ggctggactc gtgaagatct caaggcttta
    14821 cgccaacgcc atcgtactgt ggctgacaaa caaaattcta tggccaatat gatgggcatg
    14881 ccgcagactc ctagtggtgg tctcgaggac tatacgcatg atttgacaga gcaagcgcgt
    14941 tctggcaagt tagaaccagt catcggtcgg gacaaggaaa tctcacgtat gattcaaatc
    15001 ttgagccgta agactaagaa caaccctgtc ttggttgggg atgctggtgt cgggaaaaca
    15061 gctctggtgc ttggtcttgc tcagcgtatt gccagtggtg atgtgcctgc ggaaatggct
    15121 aagatgcgcg tgttagaact tgatttgatg aatgtcgttg cagggacacg cttccgtggt
    15181 gactttgaag aacgcatgaa taatatcatc aaggatattg aagaagatgg ccaagtcatc
    15241 ctctttatcg atgaactcca caccatcatg ggttctggta gcgggattga ttcgactctg
    15301 gatgcggcca atatcttgaa accagccttg gcgcgtggag ctttgagaac ggttggtgcc
    15361 accactcagg aagaatatca aaaacatatc gaaaaagatg cggctctttc tcgtcgtttc
    15421 gctaaagtga cgattgaaga accaagtgtg gcagatagta tgactatttt acaaggtttg
    15481 aaggcgactt atgagaaaca tcaccgtgta caaatcacag atgaagcggt tgaaacagcg
    15541 gttaagatgg ctcatcgtta tttaaccagt cgtcacttgc cagactctgc tatcgacctc
    15601 ttggacgaag cagcagcaac agtgcaaaat aaggtaaagt atgtaaaagc agacgattca
    15661 gatttgagtc cagctgataa ggccctgatg gatggcaagt ggaaacaggc agcccagcta
    15721 atcgcaaaag aagaggaagt acctgtctac aaagacttgg tgacagagtc tgatattttg
    15781 accaccttga gtcgcttgtc aggaatccca gttcaaaaac tgactcaaac ggatgctaag
    15841 aagtatctaa atcttgaagc agaactccat aaacgtgtca tcggtcaaga tcaagctgtt
    15901 tcaagcatta gtcgtgcgat tcgccgtaat cagtcaggaa ttcgcagtca caagcgtccg
    15961 atcggttcct ttatgttcct aggacccaca ggtgtcggta agaccgagtt ggccaaggct
    16021 ttggcagaag ttctctttga tgacgaatca gcccttatcc gctttgatat gagtgagtat
    16081 atggagaaat tcgcagccag ccgtctaaat ggagctcctc caggctatgt gggttacgaa
    16141 gaaggtggag agttgacaga gaaggttcgc aataaaccct attccgttct cctctttgat
    16201 gaggtagaga aggcccaccc agatattttt aatgttctct tgcaggttct ggatgacggt
    16261 gttttgacag atagcaaggg acgcaaggtc gatttttcaa ataccattat cattatgaca
    16321 tcgaacctag gtgcgactgc ccttcgtgat gataagactg ttggttttgg ggctaaggat
    16381 attcgttttg accaggaaaa tatggaaaaa cgcatgtttg aagaactgaa aaaagcttat
    16441 agaccggaat tcatcaaccg tattgatgag aaggtggtct tccatagcct atctagtgac
    16501 catatgcagg aagtggtgaa gattatggtc aagcctttag tggcaagttt ggctgaaaaa
    16561 ggcattgact tgaaattaca agcttcagct ctgaaattgt tagcaaatca aggatatgac
    16621 ccagagatgg gagctcgccc acttcgcaga accctgcaaa cagaagtgga ggacaagttg
    16681 gcagaacttc ttcttaaggg agatttagtg gcaggcagca cacttaagat tggtgtcaaa
    16741 gcaggccagt taaaatttga tattgcataa aagaataaaa gtatcagcat ctgaccataa
    16801 gtcacagtgg agtgaaactc aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt
    16861 tgctcaaaac actggtttga ggttgcagat agagctgacg tggtttgaag agattttcga
    16921 agagtatgaa actaaaacct atagcttcta aacgatccgt ggttttcacc attcaacaca
    16981 aaattcatat gtttattacc ctccgtcgta tttgtcttag agcgtgtgta gtagaaaaag
    17041 agcagtctta tctgaaattt ttattctttc aaaagagacc tgtttctttt ttgcatgtca
    17101 aatccgttct agctggtatt tgaaaaatca aactaatatt caatgaaaat caaagaacaa
    17161 actaggcagc tagccacagg ttgctcaaaa cactgttttg aggttgtaga tagagctgac
    17221 gtagtttgaa gagattttcg aagagtataa gctgcaagat gaatgatttt cttgtattga
    17281 cgttgttgtt gacaaaaagt agcggataaa tgaaatccat tccattatca tagatgatag
    17341 gctggtagga aattttcaaa tagcatacag gaaatagatg tatggagttc tggtagtaga
    17401 aagggagaga gatgaacatt ttagttgcag atgacgagga aatgattaga gaaggaattg
    17461 cagcatttct gacagaagag ggttatcatg tcattatggc taaggatgga caagaggtct
    17521 tggaaaaatt tcaagatctc cctatccatc tcatggtatt ggatttaatg atgcctagga
    17581 agagtggttt tgaagtgtta aaagaaatca atcaaaagca cgatattcct gtcatcgtct
    17641 tgagtgctct gggagatgaa actactcagt cacaggtatt tgatctctat gctgatgatc
    17701 atgtgacaaa acctttttct ttggtactgc ttgtcaagcg tattaaggcg cttatcagac
    17761 gttactacgt catagaggat atttggcgat atcaggatgt aacagtggat tttacctctt
    17821 acaaagcaca ttataaaaat gaagaaattg atctcaaacc aaaggaatta ctggtactaa
    17881 agtgtttgat tcagcataaa aatcaagttt taagtagaga gcagatattg gaagaaattt
    17941 caaaagatgt agctgattta ccttgtgata gggtcgttga tgtctatatt cgtactcttc
    18001 gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa tgttgggtat aagattagct
    18061 tatgataaaa aatcctaaat tattaaccaa gtctttttta agaagttttg caattctagg
    18121 tggtgttggt ctagtcattc atatagctat ttatttgacc tttccttttt attatattca
    18181 actggagggg gaaaagttta atgagagcgc aagagtgttt acggagtatt taaagactaa
    18241 gacatctgat gaaattccaa gcttactcca gtcttattca aagtccttga ccatatctgc
    18301 tcaccttaaa agagatattg tagataagcg actccctctt gtgcatgact tggatattaa
    18361 agatggaaag ctatcaaatt atatcgtgat gttagatatg tctgttagta cagcagatgg
    18421 taaacaggta acagtgcaat ttgttcacgg ggtggatgtc tacaaagaag caaagaatat
    18481 tttgtttttg tatcttccat atacattttt ggttacaatt gctttttcct ttgttttttc
    18541 ttatttttat actaaacgct tgctcaatcc tcttttttac atttcagaag tgactagtaa
    18601 aatgcaagat ttggatgaca atattcgttt tgatgaaagt aggaaagatg aagttggtga
    18661 agttggagaa gttggaaaac agattaatgg tatgtatgag cacttgttga aggttattca
    18721 tgagttggaa agtcgtaatg agcaaattgt aaaattgcaa aatcaaaagg tttcctttgt
    18781 ccgtggagca tcacatgagt tgaaaacccc tttagccagt cttagaatta tcctagagaa
    18841 tatgcagcat aatattggag attacaaaga tcatccaaaa tatattgcaa agagtataaa
    18901 taagattgac cagatgagcc acttattgga agaagtactg gagtcttcta aattccaaga
    18961 gtggacagag tgtcgtgaga ccttgactgt taagccagtt ttagtagata ttttatcacg
    19021 ttatcaagaa ttagctcatt caataggtgt tacaattgaa aatcaattga cagatgctac
    19081 cagggtcgtc atgagtctta gggcattgga taaggttttg acaaacctga ttagtaatgc
    19141 aattaaatat tcagataaaa atgggcgcgt aatcatatcc gagcaagatg gctatctctc
    19201 tatcaaaaat acatgtgcgc ctctaagtga ccaagaacta gaacatttat ttgatatatt
    19261 ctatcattct caaatcgtga cagataagga tgaaagttcc ggtttgggtc tttacattgt
    19321 gaataatatt ttagaaagct atcaaatgga ctatagtttt ctcccttatg aacacggtat
    19381 ggaatttaag attagcttgt agacagatta gttttttatt aaagttcata tagggttaac
    19441 ataagtgtgt tattctttgt gtagataaaa gaaaggatac taatatggta ttagcgatta
    19501 ttttagtaac attctttatt cgattgattt ttttaaagcg ttcgatagag aatgagaaac
    19561 gaatccttag caatggcggg aaagaatttg gagttgagaa tacaaaacga ttaactatgg
    19621 ctcatattgt tttttatctc tcttgcttgg ttgaggcaat ggtgcacaag acaatttttg
    19681 atggcatggg catggttggt ttagtcttgc ttattttttc tatgctgatg ttaatgttgg
    19741 tgattcactt gttgggagat atttggacag tgaagcttat gcttgtcaat aatcacaaat
    19801 atgtagatca tatcttgttt aggacagtaa aacatcctaa ttacttttta aatattcttc
    19861 ctgagttgat tggcttgacc ttgttgagtc atgcttatgt gacttttgtt ttagtttttc
    19921 cagtttatgc agttattttg tatcgacgaa tagctgaaga ggaaaagcta ttacatgaag
    19981 ttataatccc aaatggaagc ataaagagat aaatacaaaa ttcgatttat atacagttca
    20041 tattgaagtg atatagtaag gttaaagaaa aaatatagaa ggaaataaac atgtttgcat
    20101 caaaaagcga aagaaaagta cattattcaa ttcgtaaatt tagtattgga gtagctagtg
    20161 tagtagttgc tagcttgttc ttaggaggag tagttcatgc agaaggggtt agaagtgggg
    20221 atacccccaa ggttacatct agtggggatg aagtcgagtc gcatctaaaa aaaatattga
    20281 gtgagatcca aacacaatta gatagaaaac gacatgccaa aactgtagcg ctaattaaca
    20341 agttgcaaga cattaagaga acgtattcgt ataaattaaa tgttttagaa gagaagccga
    20401 aagctgagtt gacgtcaaaa acaaaagaag agttaaccgc agcttttgag caatttaaaa
    20461 aagatacatt accaacagaa ccaggaaaaa aggtagcaga agctgagaag aaggttgcag
    20521 aagctgagaa aaaagccgag gatcaaaaag aagaagatcg tcgtaactac ccaaccaata
    20581 cttacaaaac gcttgaactt gaaattgctg agttcgatgt gaaagttaaa gaagcggagc
    20641 ttgaactatt aaaagagaaa gctaagaaac ctttaaacga gggcacaatt aagcaagcaa
    20701 aagagaaagt tgagagtaaa aaagctgagg ctacaaggtt agaaaacatc aagacagatc
    20761 gtaaaaaagc agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagaaa
    20821 aaccagctga acaaccacaa ccagcgccgg ctcctcaacc agaaaaacca gctccaaaac
    20881 cagaaaaacc agctccagct ccaaaaccag agaatccagc tccaaaacca gaaaaaccag
    20941 ctccagctcc aaaaccagag aatccagctg aacaaccaaa agcagaaaaa ccagctgatc
    21001 aacaagctga agaagactat gctcgtagat cagaagaaga atataatcgc ttgactcaac
    21061 agcaaccgcc aaaaactgaa aaaccagcac aaccatctac tccaaaaaca ggctggaaac
    21121 aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggcgaca ggatggctcc
    21181 aaaacaatgg ctcatggtac tacctcaaca gcaatggcgc tatggcgaca ggatggctcc
    21241 aaaacaatgg ttcatggtac tatctaaacg ctaatggttc aatggcaaca ggatggctcc
    21301 aaaacaatgg
//
LOCUS       DAVBED010000038        21102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBED010000038 DAVBED010000000
VERSION     DAVBED010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.038"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ547_001407"
     CDS             <1..266
                     /locus_tag="VQ547_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2543247.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQ547_001408"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQ547_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQ547_001409"
     CDS             1469..1741
                     /locus_tag="VQ547_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2543248.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQ547_001410"
     CDS             2055..2186
                     /locus_tag="VQ547_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2543249.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQ547_001411"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQ547_001411"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2543250.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQ547_001412"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQ547_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2543251.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQ547_001413"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQ547_001413"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2543252.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQ547_001414"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQ547_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2543253.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQ547_001415"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQ547_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2543254.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQ547_001416"
     CDS             7107..7811
                     /locus_tag="VQ547_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2543255.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQ547_001417"
     CDS             7804..8610
                     /locus_tag="VQ547_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2543256.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQ547_001418"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQ547_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2543257.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQ547_001419"
     CDS             complement(11245..12018)
                     /locus_tag="VQ547_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2543258.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQ547_001420"
     CDS             12194..13597
                     /locus_tag="VQ547_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2543259.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQ547_001421"
     CDS             13712..14350
                     /locus_tag="VQ547_001421"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2543260.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQ547_001422"
     CDS             14362..14802
                     /locus_tag="VQ547_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2543261.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQ547_001423"
     CDS             14795..15226
                     /locus_tag="VQ547_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2543262.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQ547_001424"
     CDS             15217..15687
                     /locus_tag="VQ547_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2543263.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQ547_001425"
     CDS             15712..16485
                     /locus_tag="VQ547_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2543264.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQ547_001426"
     CDS             16482..17282
                     /locus_tag="VQ547_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2543265.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQ547_001427"
     CDS             17341..19635
                     /locus_tag="VQ547_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2543266.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQ547_001428"
     CDS             19645..>21102
                     /locus_tag="VQ547_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543267.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBED010000039        21004 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBED010000039 DAVBED010000000
VERSION     DAVBED010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.039"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQ547_001429"
     CDS             <1..128
                     /locus_tag="VQ547_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2543268.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQ547_001430"
     CDS             complement(176..2719)
                     /locus_tag="VQ547_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2543269.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGIYQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQ547_001431"
     CDS             complement(2781..4403)
                     /locus_tag="VQ547_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2543270.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQ547_001432"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQ547_001432"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2543271.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQ547_001433"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQ547_001433"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2543272.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQ547_001434"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQ547_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2543273.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQ547_001435"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQ547_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2543274.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQ547_001436"
     CDS             8943..10193
                     /locus_tag="VQ547_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2543275.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQ547_001437"
     CDS             10190..11473
                     /locus_tag="VQ547_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2543276.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQ547_001438"
     CDS             11515..12336
                     /locus_tag="VQ547_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2543277.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQ547_001439"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQ547_001439"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2543278.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQ547_001440"
     CDS             12889..13716
                     /locus_tag="VQ547_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2543279.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQ547_001441"
     CDS             13701..14540
                     /locus_tag="VQ547_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2543280.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQ547_001442"
     CDS             14533..15327
                     /locus_tag="VQ547_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2543281.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQ547_001443"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQ547_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2543282.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQ547_001444"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQ547_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2543283.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQ547_001445"
     CDS             16792..17970
                     /locus_tag="VQ547_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2543284.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQ547_001446"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQ547_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2543285.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQ547_001447"
     CDS             19052..20092
                     /locus_tag="VQ547_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2543286.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQ547_001448"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQ547_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(20816..>21004)
                     /locus_tag="VQ547_001449"
     CDS             complement(20816..>21004)
                     /locus_tag="VQ547_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543287.1"
                     /translation="FAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVIQGLEKE
                     VIKSIVNRRRTRMLFESR"
BASE COUNT         6680 a         3375 c         4318 g         6631 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgatagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc acctccttct
    20881 ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
    20941 gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga ggaataaatg
    21001 caaa
//
LOCUS       DAVBED010000040        20672 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBED010000040 DAVBED010000000
VERSION     DAVBED010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.040"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..187)
                     /locus_tag="VQ547_001450"
     CDS             complement(<1..187)
                     /locus_tag="VQ547_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543288.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHY"
     gene            442..1287
                     /locus_tag="VQ547_001451"
     CDS             442..1287
                     /locus_tag="VQ547_001451"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2543289.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1434..2495)
                     /gene="dinB"
                     /locus_tag="VQ547_001452"
     CDS             complement(1434..2495)
                     /gene="dinB"
                     /locus_tag="VQ547_001452"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2543290.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2843..5167
                     /gene="pflB"
                     /locus_tag="VQ547_001453"
     CDS             2843..5167
                     /gene="pflB"
                     /locus_tag="VQ547_001453"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2543291.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5534..5752)
                     /locus_tag="VQ547_001454"
     CDS             complement(5534..5752)
                     /locus_tag="VQ547_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543292.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5848..6086)
                     /locus_tag="VQ547_001455"
                     /pseudo
     CDS             complement(5848..6086)
                     /locus_tag="VQ547_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6079..6363)
                     /locus_tag="VQ547_001456"
     CDS             complement(6079..6363)
                     /locus_tag="VQ547_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543293.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6975..7145)
                     /locus_tag="VQ547_001457"
     CDS             complement(6975..7145)
                     /locus_tag="VQ547_001457"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543294.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7795..9018)
                     /locus_tag="VQ547_001458"
     CDS             complement(7795..9018)
                     /locus_tag="VQ547_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2543295.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9186..10508
                     /locus_tag="VQ547_001459"
     CDS             9186..10508
                     /locus_tag="VQ547_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2543296.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10510..12396
                     /locus_tag="VQ547_001460"
     CDS             10510..12396
                     /locus_tag="VQ547_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2543297.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12564..12908
                     /locus_tag="VQ547_001461"
     CDS             12564..12908
                     /locus_tag="VQ547_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2543298.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12918..14330
                     /gene="lacG"
                     /locus_tag="VQ547_001462"
     CDS             12918..14330
                     /gene="lacG"
                     /locus_tag="VQ547_001462"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2543299.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14400..16079
                     /locus_tag="VQ547_001463"
     CDS             14400..16079
                     /locus_tag="VQ547_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2543300.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16205..17644)
                     /locus_tag="VQ547_001464"
     CDS             complement(16205..17644)
                     /locus_tag="VQ547_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2543301.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17648..18997)
                     /gene="trkA"
                     /locus_tag="VQ547_001465"
     CDS             complement(17648..18997)
                     /gene="trkA"
                     /locus_tag="VQ547_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2543302.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19185..20033
                     /locus_tag="VQ547_001466"
     CDS             19185..20033
                     /locus_tag="VQ547_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2543303.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20048..20596
                     /locus_tag="VQ547_001467"
     CDS             20048..20596
                     /locus_tag="VQ547_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2543304.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6263 a         3513 c         4232 g         6664 t
ORIGIN      
        1 cataatgtcc ggtattttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
       61 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
      121 ttcctggaac attcaaggct gtaacatcgt gtttattttt agcgatatca atgcccacat
      181 aaagcatggg agtacctcca gatatagtat ttcaagtcta cttggttatc cacgaatttt
      241 ttgccttgtt accttagacg agatcaaacg tctatgcgtt atcaaactca ttaccaattg
      301 aaacaaaagc tgtggttaga gcctttcgga aatcgtcaag cgattggagg aaatgaacta
      361 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
      421 ttataatata gggagtaatc tatgtatctt attgaaattt taaaatctat cttcttcggg
      481 attgttgaag gaattacgga atggttgccg atttccagta caggtcactt gattttagca
      541 gaggaattca tccaatacca aaatcaaaat gaagccttta tgtccatgtt taatgtcgtg
      601 attcagcttg gtgctatttt agcagttatg gtgatttatt ttaacaagct caatcctttt
      661 aaaccgacta aggacaaaca ggaagttcgt aagacttgga gactatggtt gaaggtcttg
      721 attgctactt tacctttact tggtgtcttt aaatttgatg attggtttga tacccacttc
      781 cataacatgg tttcagttgc tctcatgttg attatctacg gggttgcctt catctatttg
      841 gaaaagcgca ataaagcgcg tgctatcgag ccaagtgtaa cagagttgga caagcttcct
      901 tatacgaccg ctttctatat cggactcttc caagttcttg ctcttttacc agggactagc
      961 cgttcaggtg caacgattgt cggtggtttg ttaaatggaa ccagtcgttc agttgtgaca
     1021 gaatttacct tctatcttgg gattcctgtt atgtttggag ctagtgcctt aaagattttc
     1081 aaatttgtga aagccggaga actcttgagc tttgggcaat tgtttttgct cttggtcgcg
     1141 atgggagtag cttttgcggt cagcatggtg gctattcgct tcttgaccag ctatgtgaaa
     1201 aaacacgact tcaccctttt tggtaaatac cgtatcgtgc ttggtagtgt tttgctactt
     1261 tacagttttg tccgtttatt tgtataagaa aaaccttgaa ggggcaactc ttcaaggttt
     1321 tatactcttc gaaaatctct tcaaaccgcg tcagctttat ctgcaacctc aaaacagtgt
     1381 tttgagcagc ctgcggctag cctcctagtt tgctctttga ttttcattga gctttaaaat
     1441 ccagtcatgg taatccccaa taggcggaca cctctttctt tcttgcttaa ttcttcatag
     1501 agttgcaggg ctatttggct tatctgacta gcatcttgtg ttttttgagc aagacttttt
     1561 cgtttggtaa gagttgaaaa gtcctcgtag cggattttca aaatgacaat ttttccagct
     1621 ttttcttgtt gatgtagatt gagagcgact ttttctgata gaagagtcag ctcttttttg
     1681 atatcttcct cagcaaggag aatcttcccg taggttttct ccttgccgat tgatttacgg
     1741 atgcgattgg atttgactgg agagttgtga atgccacgag cctttcgata cagatcatag
     1801 cctagtctac caaaacggtc tattagggtt acctcaggaa cttcaagtaa atcagcacca
     1861 gtaaaaacgc ccatttgatg aagacgttct actgtctttt ttcctactcc atgaaatttg
     1921 gaaatatcca tttgtttgag aaaatcctca gcctgttcag gtagaatcac tgtcaaacca
     1981 tgtggttttt gataatcact cgccatttta gctaagaatt tgttgtaaga aacgcctgcg
     2041 gaagcagtta gatggagttc ttgccagata tctttttgaa tgaggcgagc aattttgacc
     2101 gctgacttga taccgagttt attttctgtc acatccaaat aggcttcgtc aatgctcatg
     2161 ggttcaatca aatctgtata gcgcttaaaa atagctcgaa tctggagtcc cacagacttg
     2221 tatttctcat aattccctga gataaagaca gcctggggac aacgttcata agcttccttg
     2281 gaactcatgg cagaatggac accaaaagct cttgcctcat aactacaggt agaaacgact
     2341 ccccgtccac ctgtttgccg agggtcgctt ccaataatga caggttttcc tctgagttta
     2401 ggattatccc tgatttccac tgcagcaaaa aaggcatcca tgtcaatatg gatgattttt
     2461 cttgacaaat catttaacaa aggaaaaatc aacatgccta gcaccttttt atactcttcg
     2521 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt ttgagcaatc
     2581 tgcggctagc ttcctagttt gcttttcgat ttccattgag tgttactgct tattttcttt
     2641 tattataccc ttttttctga aaaaaagaaa aaaggacttt attttttcaa aaatataata
     2701 cagtttgaaa taaaatatag actgttttag aaaagaaagt gtaaaaatag ggaattttca
     2761 cttgttgaaa tcggttacta tatggtatac ttgtcttatg aatgtaacag atgactgtta
     2821 ctagaaaaaa gaggacatta atatggttgt taagacagtt gttgaagcac aagatatttt
     2881 tgacaaagct tgggaaggct tcaaaggcgt agattggaaa gaaaaagcaa gtgtatcacg
     2941 atttgtacaa gctaactaca caccttatga tggagacgaa agcttccttg caggaccaac
     3001 agagcgttca cttcacatca agaaaattgt agaagaaact aaagcacact acgaagaaac
     3061 tcgtttccca atggacactc gtccaacatc tatcgctgat atccctgctg gatttatcga
     3121 caaagaaaat gaagttatct tcggtatcca aaacgatgaa ctcttcaaat tgaacttcat
     3181 gccaaaaggt ggtatccgta tggctgaaac tactttgaaa gaaaatggat acgaaccaga
     3241 cccagctgtt cacgaaatct tcactaaata tgtaacaaca gttaacgacg gtattttccg
     3301 tgcctacact tcaaatattc gtcgcgctcg tcacgcacac actgtaactg gtcttccaga
     3361 tgcatactca cgcggacgta tcatcggtgt ttacgcacgt cttgctcttt acggtgcaga
     3421 ctacttgatg caagaaaaag taaatgactg gaatgcaatc aaagaaatcg atgaagaaac
     3481 aatccgtctt cgtgaagaag taaaccttca ataccaagca ttgcaacaag ttgttcgcct
     3541 gggtgacctt tacggggttg atgttcgcaa accagcgatg aacgtgaaag aagcaatcca
     3601 atgggttaac attgctttca tggctgtctg ccgtgtgatt aacggtgctg ctacatctct
     3661 aggtcgtgta ccaatcgtat tggacatctt tgcagaacgt gaccttgctc gtggtacatt
     3721 tactgaatca gaaatccaag aattcgttga tgatttcgtt atgaaacttc gtacagttaa
     3781 atttgctcgt acaaaagctt atgaccaatt gtactcaggt gacccaacct ttatcacaac
     3841 ttctatggct ggtatgggta acgacggtcg tcaccgtgtt actaagatgg actaccgttt
     3901 cttgaacact cttgacaaca tcggtaactc accagaacca aacttgacag ttctttggac
     3961 tgacaaattg ccatacaact tccgtcgcta ctgtatgcac atgagccaca aacactcttc
     4021 tatccaatac gaaggtgtaa caacaatggc taaagacgga tatggtgaaa tgagctgtat
     4081 ctcatgctgt gtgtctccac ttgatccaga aaatgaagaa caacgccaca acatccagta
     4141 cttcggtgct cgtgtaaacg ttcttaaagc ccttcttact ggtttgaatg gtggttacga
     4201 cgatgttcac aaagactaca aagtatttga tatcgaacca atccgtgacg aagttcttga
     4261 atttgaatca gttaaagcga actttgaaaa atctcttgac tggttgactg acacttacgt
     4321 agatgccttg aacatcatcc actacatgac tgataggtac aactacgaag ctgttcaaat
     4381 ggccttcttg ccaactaaac aacgtgccaa catgggattc ggtatctgtg gatttgctaa
     4441 cactgttgat acattgtcag ctatcaaata cgctacagtt aaaccaatcc gtgacgaaga
     4501 tggctacatc tacgattacg aaacaatcgg tgactaccca cgctggggtg aagatgaccc
     4561 acgttcaaac gaattggcag aatggttgat cgaagcttac acaactcgtc tacgtagcca
     4621 caaactatac aaagacgcag aagctacagt atcacttttg acaatcacat ctaacgttgc
     4681 ttactctaaa caaactggta actcaccagt tcacaaaggt gtatacctca acgaagatgg
     4741 ttctgtgaac ttgtctaaac ttgaattctt ctcaccaggt gctaacccat ctaacaaagc
     4801 taaaggtggt tggttgcaaa acttgaactc actttctagc cttgacttta gttatgcagc
     4861 tgacggtatc tcattgacta cacaagtatc acctcgcgct cttggtaaga ctcgtgatga
     4921 acaagttgat aacttggtaa caatccttga tggttacttc gaaaacggtg gacaacacgt
     4981 taacttgaac gttatggact tgaacgatgt ttacgaaaaa atcatgtcag gcgaagacgt
     5041 tatcgtacgt atctctggat actgtgtaaa cactaaatac ctcactccag aacaaaaaac
     5101 tgaattgaca caacgtgtct tccacgaagt tctttcaatg gatgacgcct tggatgcatt
     5161 gagctaatca agttcttgaa taataaaaag gaaccctcgg tcaaacgact gagggttttg
     5221 tgcttgggat agtatgagca attccttcgg cgcaatatgc aatgtttttg ggaaggaata
     5281 gtggaccgaa tctgaaatat aatagattga aactagaata gtacaccttt acttctaaaa
     5341 cattcttaga aatcgatttg actgtcctga tcgatttgtc ctattcttat ttcattttac
     5401 tatagtccgc tgaaacggct caaacagtgc tagaaattga ctggaattct ctaagtgatt
     5461 tgttccgatt ttatttcatt tcatcataaa aataagatga ctggctaatt gacaatcatc
     5521 ttgtttgata ctgttaataa aattcgcgaa gtttatcttg attttcttta aaaaattttt
     5581 ctaaccaatc cataccataa gcataactaa aaccttctaa tagaacagag aggtcaatag
     5641 tatcaaatcc catgtctttt aaatatttaa aggtatcgaa tggtgaatga aagtttttgt
     5701 atttaataat tgcaccaata tcttgcaaat cctgctctct gatactcatc atcttcattc
     5761 ctaacacata ctcaataggg actactaaaa cggtcagatt ctcaaatgag tacaaggatt
     5821 cgcataaact taagggaggt tgtttgttca tatttgcttt gcaacatgat tgttgagcca
     5881 taactcttcg tggatgttaa gattaaactg ttttcctaca cgagcaataa tttcattgat
     5941 tttctgattt tggtcataaa aagcatcaac atcttgtgtg gcacgtaaac catgatattc
     6001 taagacataa ccataattgt taaagtcaga ttttcctgaa ttaatttctt atttagggct
     6061 tggaagaccg gtttcatttt atccatgttt gtatttctcc atcaattttt gaacattggt
     6121 taacttagca ggtttattta atgaaatcac atatttatga gttggagtat gctcttgaaa
     6181 ggcatacttc aagctaattt tttgaaaacg ggttagttct ttggagtcta gcaacttttc
     6241 tacatcttgg tttgttaaat aagaatagtc ttcaaaaata acttttcgca aatagcgaaa
     6301 ccaatggctt gcgttgaatt gtgattgttt ggatgcctgt atcatataat cgtaccaatc
     6361 cattgtcttc ctcctataaa atttagttta tattattgta gtttatattc aaaaatgtag
     6421 tttttcttaa ttagctcgta tctataggat gatactgaaa atcttcttgt tgctttaaat
     6481 cacaatcgaa aaattctgtt tttcatctta gaaaagaatg tttagaaatg taaaatgaac
     6541 cttttttctt atccgaaaac cttactaaag tatataattt aggcagtcaa ttctgtatga
     6601 taatgtttgt actatcgtcg agtttttgct tgattgccta acgagataaa ttttagaaga
     6661 gttttcggtg tgatttgaca agtttctgac tggaaggata gttacactag tattgtttat
     6721 taaaatgagc agatagagaa aatttggaat ctatttgctt attatcaatc gtttttttag
     6781 cttatttgtc ttagattggt atagaactga gctatggatt aatcttcttc tatcttatcc
     6841 tgttcctaaa tatgttggta gaaaaatgaa gcagttgtta cgagtgtctg tattgggaaa
     6901 aattttgtct atagaattct ttaaatgata tgaaggctag gaatgccaaa acactgacat
     6961 atttcgttta aagtctatcc agtctcttca attgtatttg tagaaatgct atcagtaata
     7021 tattcgcgaa cactatgatt tacaacagtg tggtcgtaca tctttgtaac tttattatac
     7081 aacaaccatt tacaggtgta aagttgagca gtgtctttag taaatttagg gacttgtttt
     7141 gtcatagttt tgatacctgt attcgttgtt tcatgagcat ttgacgtttc ttttcatgta
     7201 ggcatttcaa caattagaat gatatttttc cgaggatgaa cttatatatt gtgacttttt
     7261 agagttatga tgcctcttga tttgactacc gctatcaatt tcatccactt ttacagtttc
     7321 atggttttat gaaccgaaac atctaggtac aggttttagc atcaattgat tgtttttgag
     7381 ccatatgaag ttgaaacgtg gagatgcttt tcttgtgata acgccctatt caaagaggaa
     7441 taaccgtttt tggagagagt tcagtactat gtggcgctaa atactatatg taaaacatat
     7501 attaaacaag atttaactaa ggagaattgt aaaaacaaaa atgagaattt catataaagt
     7561 ttattctagg agtatgtatc ttgaataaaa atcgttattt aagttcaggg ttatgatgaa
     7621 tgtttttata ataataaaat gcagctagaa gaaaagttat tttaatataa atcactcaac
     7681 atagagagaa ggcggtttcc tatatggaag tcgtcttgtt ttcatattgt ctaaatacga
     7741 gatatctact acaggttata gttgatttaa acaggtctat agatttctaa tatattaagg
     7801 tgaaataata tcttgtaata cattgctatg ttctatgaaa aaagcgacga tagctaatgc
     7861 acaagctcct atacttccac gatgtttgtt gtaaggtaaa atttcaattt ctatattacg
     7921 agtaaaggga acgaagtgga gctggtcttg gattttatcc ctgacttcat gagtgaaagg
     7981 ttgataatta agcaattgac tgttgatata gattttatca gcaggattga tgaggaggag
     8041 atttgcaata gaagtggcta ataaattgac tcctttatca atttgttgac gtaaagcgga
     8101 gtcgcctaaa ttataagccg ttaaaagggt gtctaaatga atgtcttttt cagtctttac
     8161 aaggcttttt agtacagtta gttgggaatt tttaaataat aattgggcgt gtttgattaa
     8221 ccaagcatcc gaaatatatg tttgtaaaca accttttttt ccgcattcac aatattgccc
     8281 attcaattcg acaatggtgt gtccaatttc tccgatataa ggatttttag aggctcctat
     8341 tttttctttt gtgaaaaagg aagtgtaaat acctaatcca gcgtgtagga aaataaagtt
     8401 atcgggggta ttgtgtggat taaaaaggta ttgtcctata gccatacaat cgatattatt
     8461 ttttacaata aaaggaaaat tgaatctttt aattacattt aataaattaa aagattccca
     8521 tatggggttg tttgtaatga tacttccgga gtctttgtta taatgtccag gtattgataa
     8581 gccaaatcca agtaattttg tttccaaagg gacgtactct atagctgttt ttatcatatt
     8641 ggtaatggtg gaattgattt ctgaaatagg ataatcttca ttcaaaattt ctgtctcgaa
     8701 aagagttttc ccttgtaagt cacatagact gagaaagata cctaggacgt ttatttcaat
     8761 acctccaaca acatacggaa tattatctgt gatagaaata gtttttctac gtcttccaga
     8821 tccggaaaac tcgctaaatt catcaccagt ttcgtatatg agggactgtt cgcttagctc
     8881 ttttatgatg ttagtcgttg ttgctggagt aagtcctgtt tcattaacaa tatctgtacg
     8941 ggatgttgct ggatttcgat atagaaactc cagtatagtg gctctatttt gtaaaaaggc
     9001 tgattgtttt gtaatcattt gtttcctcct ttggtttatt ttatattaaa cataagaaaa
     9061 aatcaattaa aattattatt ttatacaaag aaaaaaatat tgtaaaaaca acaaaaaata
     9121 tattgacaac gctttctgtt agtggtatat ttaatttata aaaaataaaa aaaggagttc
     9181 cggtgatgaa caatatttta gcgtttttag aaacaaaagt cgctccgttt ggtgaaaaag
     9241 ttggcaacca acggcatttg aaagctattc gtgaaggatt tatgatggca atgcctttga
     9301 ttttagtcgg atctttattt cttattctaa tcagttggcc tcaagaggat tttacaaatt
     9361 ggctgaatag tgttggattg ctaagtatct tgacaactat gaatcagtca acagtagcga
     9421 ttatctcctt ggtcgcttgt ttcggtattg cctacaggtt gtcggaagga tatggtacag
     9481 atggtccgtc ggcagggatc atagccttat ccagttttgt attgatggca cctcgttttt
     9541 cgagtatggt ttatgataaa aatggggagc aggtcaagca gttatttggc ggcgcaatac
     9601 cattttctag cctgaatgca tcttctttgt ttatggcgat tactattgga ttggttacag
     9661 cagagattta tcgtatgttt atccagcgcg gaattacgat aaaaatgcca agtggtgtcc
     9721 cagatgtggt aagtaaatca ttttcagctc ttttacctgg ctttactact tttgttttgt
     9781 gggctctggt cttaaaaggt cttgaagcgg caggagttgc aggaggtctc aacggactcc
     9841 taggtgcaat tgttggaaca ccgcttaagt taattgcagg aacgcttcca ggtatgattc
     9901 tatgtgttat tgtaaactca ttcttttggt tctgtggagt taatggggga caagttttaa
     9961 atgcttttgt agatccagtt tggttacaat ttactacaga aaaccaagaa gctgtggctg
    10021 caggacaaac actccaacac attattacat taccgtttaa agatttattt gtatttattg
    10081 gtggcggtgg agcgactatt ggtcttgcga tttgtctctt cctatttagt aagagtcgtg
    10141 cgaataaaac attaggtaag ctagctatta taccgtctat ttttaatatc aatacagcta
    10201 ttctatttac gtttccaaca gttttaaatc cgattatgct gattccgttt attgctactc
    10261 ctacaatcaa tgccttaatt acctatgtat caatggctgt aggattagta ccctacacaa
    10321 caggtgtaat ccttccgtgg acaatgccac cgatcatagg aggcttcctt gcgacaggag
    10381 ctagttggcg aggagctcta ttacaagttg ttttgatttt ggtttctgta gcaatttatt
    10441 atccattctt caaaattgca gataaacgca atcttgaaaa agaaaaagct actgttggag
    10501 ggaaataaga tggttatcag agtatttgat cagcagaaaa atacttattc tagctttgcc
    10561 ttagaggaat taagttacta tataaatcgg gtctttaaga ctgacataga acttgtcgag
    10621 gagaaggaag cggatatttt tgtaggatta gtcaataaag aggatagaaa agaccatgtt
    10681 cttatctcat tagacaaggg taaggggaga attgagtcta atacaattgt aggtttgctt
    10741 attggaattt accgaatgtt tcatgaattt ggggttgtgt atactagacc agggcgcgga
    10801 catgactttg ttccagagtt acgatttgaa gattttttag ataaagagct atctatagat
    10861 gaaacagcca gttactatca taggggagta tgtatagagg gagcagattc atttgaaaat
    10921 atactagatt tcattgattg gctacctaag attgggatga acagtttttt cattcagttt
    10981 gaaaatccct attctttttt gaaacgttgg tatgaacatg agtttaatcc atacctaaat
    11041 aaagaaaaat tctcaaatga attagtacaa gaattgagtg ataggttgga taaagaattg
    11101 caaaaaagag gtcttattca tcatcgtgtt ggtcatggat ggacaggtga ggttttaggt
    11161 tactcttcaa aatttggctg ggaatcaggt cttagtattt cagaggagaa gaaaccctat
    11221 gtcgctgaaa taaacgggaa acgagaatta tttaatacgg ctccgatttt aaccagtctg
    11281 gatttttcaa atccagatgt ggcggataag atggtagaaa ttatcaagga ttatgccaag
    11341 aaaagacctg atgttaacta cttacatgta tggttgtcgg atgctcgtaa taatatttgt
    11401 gaatgcgaaa actgtagaca agaattggtt tcggatcagt atattcgtat tctcaatcaa
    11461 ttggataggg ctttaacgag tgagggatta gatacaaaga tttgttttct gctttaccat
    11521 gagttgttat gggcgcctca gaaagaaaaa ttagataatc ctgaacgctt taccatgatg
    11581 tttgcaccga ttacaagaac atttgaaatg agttatgcag atgtagattt tgacaattcc
    11641 atacctacgc ctaaacctta tctgcgtaat aaaattatac ttccgaattc tcttgaggaa
    11701 aatttatctt atctttttga gtggcaaaaa acatttaaag gagatagttt cgtatatgac
    11761 tatcctttag ggcgtgctca ttatggcgat ttaggctata tgaaaattag tcaaaccatt
    11821 tacagagatg tatcttatct ttctaaccta catttgaacg gttacatttc gtgtcaagaa
    11881 ttacgtgccg gattccctca taattttcct aattatgtta tgggggaaat gctctggaag
    11941 aagacaagaa gttatgaaga attgattgaa gaatactttt ctgctttgta tgggtcaaat
    12001 tggcagtctg ttgttgaata tttagaaaaa ttatccagtt attcctcatg tgattatttt
    12061 aatgcaattg gcagtcgtca aaatgatgtt ttagcgaatc attattatat agcttacaat
    12121 ctagctgata attttttgcc aattattgag gaaaatattt ctaagttatt aaatagtcaa
    12181 aaggatgaat ggaaacagct cagttatcat cgtgaatatg ttgttaagat ggcgaaggct
    12241 ttatatcttc aagcaaccgg aaaaacaagg caagctcaag atgaatggag aaatgtgttg
    12301 aattatatcc gtgggcacga attgctattt caatctaatt tggatgttta tcgtgtaatt
    12361 gaagtagcaa aaaattacgc tggtttccac ttataaatca taagtataga aaatgaacca
    12421 aggtattcag agaagattga tcctaaatat tatgaaattt aaggattttt aagatattta
    12481 gggtcgactt tctatttata tcgtagcgaa gtcattttaa taatgatgtg taaaagatgg
    12541 atcaagattg aggaggaaga aagatgaaat caaaagaaga aataaatatg cttggtttta
    12601 caattgtcgc ttacgcagga gatgcaaggt cagatttgat ggatgctttg gcgtttgcga
    12661 gagatggata ttttgaacag gcaagagaat tggttgagtc tgcaaacgac tcaatagtgt
    12721 ctgcccatcg agaacagact aatttattag cggaggaggc atctggagat aattttgaag
    12781 tgagttttat catgattcat ggtcaagata ccttgatgac aacgatgcta ttgtatgatc
    12841 aggtcaagtt ttttattgat gaatatgaac gaattcgaaa gattgaagaa catattggtt
    12901 tgcaatgagg attagtcatg gaaaatttac aggttaaagc cttaccgaag gagtttttat
    12961 taggagctgc taccgctgct tatcaagtag agggtgcaac tagggtagat ggcaaaggaa
    13021 caaatatgtg ggatgtttat ttgcaagaaa acagtccgtt cttaccagat ccagctagtg
    13081 atttttatta tcgttacgaa gaggatataa ctttggcggc agaacatggt ttgcaggctt
    13141 tgcgtttatc tatttcttgg gttcgtatat ttcctgatat agatggggag cctaatatat
    13201 tagctgttcg ttattaccat agagtctttc agtcttgctt aaaacataat gtgattccgt
    13261 ttgtttcttt acatcatttt gattcgcctc agaaaatgtt agaaacaggg gattggttga
    13321 atagagagaa tattgatcgt ttcatacgat atgctcgctt ttgtttccaa gaatttacag
    13381 aagtcaagca ttggtttaca atcaatgaac tgatgtctct tgctgcaggt caatatatag
    13441 gaggtcagtt tcctccaaat catcattttc aattatctga agcaattcaa gcgaatcata
    13501 atatgttgtt ggcgcatgct cttgcagtcc tcgaatttca tcaattagga attgagggag
    13561 agataggttg tattcatgct ttaaagccag gctatcctat tgatgggcaa aaagaaaata
    13621 ttttggcagc taaacggtat gatgtttata ataataaatt tctattagat ggaacttttt
    13681 tgggctacta cagtgaggac acgctttttc acttgaatca aatattggaa gctaataatt
    13741 ctagctttat tattgaagat ggtgatttag aaattatgaa gagagctgca gctcttaata
    13801 cgatgtttgg gatgaattat tatcgttcag aatttattcg tgaatacaaa ggtgaaaata
    13861 gacaagaatt taattcaaca ggaataaaag gacagtcttc ttttaaatta aatgctctag
    13921 gtgaatttgt aaaaaaacct ggtattccga caacagattg ggattggaat atttatcctc
    13981 aagggttatt tgatatgttg cttcgtatca aagaagaata tcctcaacat ccggtcattt
    14041 atttaactga aaatggtaca gcccttaaag aagttaagcc agagggcgag aatgatatta
    14101 ttgatgacag taagagaatc cgttatattg agcaacattt acacaaagtt ttagaggctc
    14161 gagatagagg agtcaatatt caaggctatt ttatatggtc tttgcaagat caattttctt
    14221 gggcgaatgg ctacaataag cgatatggtc ttttctttgt tgattatgaa acacagaaga
    14281 gatatattaa gaaaagtgct ctttgggtaa aagggctaaa acggaattaa ggttagcgat
    14341 ttgactgatg tttaatatat tttaactatg agcttaaatt ttttacagga ggagttttta
    14401 tggataagtt agtcgctgcc attgaaaagc aacaagggaa atttgaaaaa atttctacta
    14461 ataattatat gatagctatt aaagatggat ttattgctac tatgccttta attatgtttt
    14521 caagcttttt gatgattatt attatgattc ctaaaaattt cggagtagag ttaccgagtc
    14581 cagctattgc ctggatgagg aaagtgtata tgctaaccat gggagttttg ggtattattg
    14641 tttcagggac agttgcaaag tcattggctg gaaatgttaa tagaaaaatg cctcctggaa
    14701 aggtaataaa tgatacttct gcaatgttgg cggccatatg tggctatctt gtattaactg
    14761 taacgcttgt agttgatgag aaaacgggat ctacaagttt gtcgacaaac tatttaggat
    14821 ctcaaggatt gataacttcg tttgtcagtg cctttattac tgtaaatgtt taccgattct
    14881 gtattaagcg agacattact attcatttac ctaaggaagt tcctggggct atatcacaag
    14941 cttttagaga tatttttcct ttttcttttg ttttacttat tagtggtttg ttagatattg
    15001 tatctcggtt tagtttagat gttccttttg cccaagtatt tcaacaacta ttgactccta
    15061 tttttaaggg ggcagaatca tatcctgcta tgatgttgat ttggtttatg tgtgctttgc
    15121 tttggtttgt tggaattcat ggaccatcta ttgtcttacc tgctgttaca gctttacaac
    15181 tgagcaatat ggaagagaat gctcaacttc ttgcaaatgg gcagttccct tatcattctt
    15241 taacacctaa tttcgggaat tatatcgctg ctattggagg aacgggggct acctttgttg
    15301 taccatttat tttgattttc tttatgcggt ctaaacaatt aaaatcggta ggtaaagcta
    15361 caattactcc tgttttattt gcggtaaatg aacctcttct atttggtatg cctgttattt
    15421 tgaatcccta tctttttgtc ccttttttga tgactccacc agtgaatgta tttctaggaa
    15481 aggtatttat tgatttcttt ggaatgaatg gattttatat ccagttacct tgggcctttc
    15541 ctggtccctt gggattgtta attggaacga attttcaact tatctccttt gtatttttat
    15601 ctttgatgtt agttgtcgac atattgattt atttgccatt ctgtagagcg tatgatagac
    15661 agttactggt gaaagaagat attgcaagct caaatgatat tattttagag gaggatacaa
    15721 gtgaaataat gcctggtgag atagatgtaa taaaaagtaa ggagttgaaa gtactggttc
    15781 tttgtgcagg gtctggaaca agtgcgcaat tagccaatgc aattaacgag ggcgctcaat
    15841 tagcagaagt tagagtgatt gcgaattcag gagcgtacgg agctcattat gatattatgg
    15901 gtgtttatga tttaattatt ctggccccac aagttcggag ttattataga gagatgaagg
    15961 tggatgcaga aagattagat attcagatag ttgctaccag aggaatggaa tatattcatt
    16021 taacaaagag tccaagtaaa gccttacaat ttgtattgga gcattaccaa gctgtgtagt
    16081 aagtttttcc atcttttatt tgagtaaaga ttttgcttac agataggctt ggatttaaaa
    16141 acgttccccc ttttttaata taagaatccc tctttcacaa ttgtaaaaag agggattttg
    16201 tattttatct cttagaccaa gttctcttca taaagagaag gaggattggg taaatctcca
    16261 agcgccctgc aatcattgca aaggatagga gaatttttga gatgggacta aagattgaga
    16321 aactagaagt ggttcctaga ataggcccga tattattgaa acagctaaag acagcgctgg
    16381 tcacgaccag aaaatcattg ctatctaggc tgacaataaa gataagcgct agcaaaatca
    16441 tagcatagat gacaaagtac ttgagaatct tatgctgggt atctttgtca atcaccgttt
    16501 tattaacatg gagggtcaaa acacggtggg gcgataggat tgacaaaatt tggtttttgg
    16561 caatttttga aaggatgagg cctcgaataa tcttgagtcc acctgcagtt gatccagcag
    16621 agccaccgat tgccatgagg aaaaggagga taaactggga gaagaggggc cagttggtaa
    16681 tatctccata tccaaaacca gttgttgtaa tgatgttgga aacctggaag aaggtcattt
    16741 caaagctctt tgaaaaccct gggtagaggt agagggtgtt gaggctaatc aagcctgtag
    16801 aaaccagtac aatgaccaag taagccctaa gctcttcatc tccaaagaag gccttgatgc
    16861 gacggagcat gaggtagtag tagaggttga aatttactcc aaaaaccaga actccgatac
    16921 tgaccagata ggtaatcagt gagctgccat agtgggcaat tccgtcgtta tagacggtaa
    16981 agcctccagt tcccgctgtc cccatagcaa tgacaaaact atcgtagaga ggcataccag
    17041 ctagataata gatgatgaca aagagggaga agagagctag ataaaggaga tagagaatct
    17101 gggcagtgtt ttttagtttg gatacaacct tgccaaaaac aggacctgga acctcagcct
    17161 tcatcacctc taggtggcta tttttggcat tgtccataat agcaagtgca aaaacaagca
    17221 ctcccatccc tccaatcaag tgggtaaaac ttcgccagaa gaggagggaa cgactgagaa
    17281 ctgaaacgtc gttcaaaata cttgctccag tagtcgtaaa gccggaacta atctcaaaaa
    17341 aggcatcaat aaggctgggg atttgcccag aaaagacaaa ggggagacca ccaaagaaag
    17401 accaaaggat ccaacagagg gcaacgatca agactccctc cttggcataa atccgttgat
    17461 tttttggctt ctgtaaactc cctgaaccgc ctaacaatac gagaatccct atggtcgaaa
    17521 agagggctgt aaagacttgg ctcgattcac ggtaatagac agcgatagcc acaggaacca
    17581 agaggagaac agcttcaatc aaaagtaact ttgaaaggag gtaacgaatc atacttttat
    17641 tcatttctta cctcgcaatc aagtcataaa tcttggtgat gtttggcaac aaggttgtta
    17701 ctaggagctt gtctccaact tccaacatat cctccccagt tgggaaaata gtcttgccct
    17761 ttcgaataat ggctgcaata agaacccctt ttttcaattt cagttgagaa agaggtttgg
    17821 cagtcatttt attggcttcc ttgatatgga attgcagggt ttcgatttgg ccattggcta
    17881 gatggtgcat ggcttgaagg tctgaatact gggcattaac tcgaccacga ataaagtgca
    17941 taatcgtatc tacagcgatg cttttaggtg tgatgatact tgaaaaatca ggcgcattga
    18001 taatctcgag gagactggta cgattgacct tagtaatatt tttctgtaca cctaccctgt
    18061 caaggaacat agatgtaatc agattttcct catcgactcc tgttagagtc gcaacggcat
    18121 catagtgttg agcactttct tccagcagga tatcttttgc ggttccatct ccttgaacga
    18181 tgtagagatt tgggaatttc tcgctaaaga agctggcgat ttcaggattg atttcaatga
    18241 cttttgtatc gatacgacta tctttgagaa taccaagtag ataataggca attctacctg
    18301 ccccaacgat gagaaggctc ttcacggcgc gtgatttaaa ataattatgg aagagtatca
    18361 tatcgacacg gttaccagtg acaaagattc tatctttatc ctgtacagtc atgtcaccgc
    18421 ttggaatgat aatttgatga tccctctcta tcgcacagac aatgacatta ccaaattttt
    18481 tacgaaaatc agaaatgggc atttggcaaa gaccgctggt ggacttgacg acaaattcca
    18541 tgaggctaac gcgtccacca gcaaagcgtt cgacagacag ggcgttgggg aagtcaatga
    18601 tattcgcgat agcacgggca gccaagagct caggattaac gataagagaa aaaccgagaa
    18661 tattcttttc cttgaaataa gagttagaat attcagggtt ccgcacccga acgatagttt
    18721 ctttagctcc cattttcttg gctagaactg ctgcaatcat gttgacttca tcgtgctcag
    18781 tcagggcgat aaagatatca caatcttgga cgctggcttg ctcaagaatg gcaaaatcgg
    18841 ccccgttacc aaggatacca atgatatcaa agcgactgac aatatgattg agaacagctt
    18901 cgtcttgctc aatcagcaaa acatcatgct tttctgcaac caaggagcga cagagggcaa
    18961 aaccaacttt tccccctccg acaaggataa ttttcataat aaaacctact ttttcatgat
    19021 gtaactatca tacccttttt caagaaaaaa tgcacctact agctaataac aagagctttt
    19081 agtgaaaatt cgctataaga taaaactata ccctaaccaa ttgaaatagc tattagcgac
    19141 tttctctgaa atatggtatg ataaaggata tacaaggaga taaaatgaat aataatttac
    19201 tggtattaca atcagacttt ggtctggttg atggtgcggt atcggctatg attggagtgg
    19261 ctttagaaga gtctccaacc ttaaaaatcc atcacttgac gcacgatatc acgccttata
    19321 atatttttga ggggagctat cgtctctttc agacggtgga ttactggcct gagggaacga
    19381 cgtttgtatc ggttgtcgat ccaggtgtcg gttcgaaacg taagagtgta gttgccaaga
    19441 ctgcaaaaaa tcaatacatt gtcacgccag ataatgggac gctttccttt atcaagaaac
    19501 acgttggcat tgtagccatt cgtgagattt ctgaggtggc caataggcgt caaaacacag
    19561 agcattctta taccttccac ggtcgtgatg tctatgccta tactggtgct aaactggcca
    19621 gtggtcacat tacttttgag gaagtagggc cagagctcag tgtggaacag attgtagagc
    19681 ttccagtcgt agcgaccatc atagaagatc atctggtgaa gggagccatt gatattctgg
    19741 atgtgcgttt cggttcgctt tggacctcta tcacacggga agaattttac aagttggaac
    19801 cagaatttgg tgatcgtttt gaagtgacca tctatcatgc tgatatgctg gtctatcaaa
    19861 atcaggttgt ctatggcaaa tcatttgcag atgtgagaat tgggcaaccc atcctttaca
    19921 tcaactctct ctatcgttta ggtttggcta tcaaccaagg ttcctttgcc aaggcctata
    19981 atgtaggtgt cggttcatct tggaccattg aaataaagaa aatagaagga taaaatagga
    20041 gaatagtatg gaaatcaaat ttacaattaa acaagttgtt gctgtcggaa ttggcgctgc
    20101 cctctttgtc gtcatcggga tgatcaacat tccaacccct gttccaaata caagcatcca
    20161 gcttcagtat gcggtacaag cgctactttc tattattttt ggaccgatta tcggtttgct
    20221 tgttgggttg attggtcatg caatcaagga ctctcttgtt ggttatggtc tatggtggac
    20281 ttggattatc gctagcggac tctttggttt agttgtggga ctttttagaa agtacgttcg
    20341 cgtgatcaat ggtgtttttg actggaaaga tattcttatt tttaacctca ttcaactact
    20401 tgcaaatgcc cttgtttggg gtgtcttggc accacttgga gatgttgtga tttatcaaga
    20461 agcggcagaa aaagtatttg cacaaggaat tgttgcggga attgccaatg gtgtatctgt
    20521 agctattgca ggaactcttc tcttacttgc ctatgcagga acccaaactc gtgcaggaag
    20581 tttgaaaaag gactaatact caatgaaaat caaagagcaa actaggaagt tagccgcagg
    20641 ttgctcaaaa cagtgttttg aaattgtgga ta
//
LOCUS       DAVBED010000041        20158 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBED010000041 DAVBED010000000
VERSION     DAVBED010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.041"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQ547_001468"
     CDS             63..527
                     /locus_tag="VQ547_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2543305.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQ547_001469"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQ547_001469"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2543306.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQ547_001470"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQ547_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2543307.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQ547_001471"
     CDS             1667..2596
                     /locus_tag="VQ547_001471"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2543308.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQ547_001472"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQ547_001472"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2543309.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQ547_001473"
     CDS             3812..4648
                     /locus_tag="VQ547_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2543310.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQ547_001474"
     CDS             4684..5001
                     /locus_tag="VQ547_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2543311.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQ547_001475"
     CDS             5003..6697
                     /locus_tag="VQ547_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2543312.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQ547_001476"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQ547_001476"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2543313.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQ547_001477"
     CDS             8355..8537
                     /locus_tag="VQ547_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2543314.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQ547_001478"
     CDS             complement(8815..9576)
                     /locus_tag="VQ547_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2543315.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ547_001479"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ547_001479"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2543316.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ547_001480"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ547_001480"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2543317.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ547_001481"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ547_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2543318.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQ547_001482"
     CDS             13717..13980
                     /locus_tag="VQ547_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2543319.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ547_001483"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ547_001483"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2543320.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..18424
                     /gene="phtA"
                     /locus_tag="VQ547_001484"
     CDS             15974..18424
                     /gene="phtA"
                     /locus_tag="VQ547_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2543321.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            18582..>20158
                     /locus_tag="VQ547_001485"
     CDS             18582..>20158
                     /locus_tag="VQ547_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2543322.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         6438 a         3612 c         4158 g         5950 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
    16081 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
    16141 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
    16201 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
    16261 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
    16321 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
    16381 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
    16441 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
    16501 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
    16561 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
    16621 taagaatgag ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg
    16681 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt caagaacaaa
    16741 ctgggtacct tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa
    16801 cactaacagt caagcaagtc aaagtaatga cattgatagt ctcttgaaac agctctacaa
    16861 actgcctttg agtcaacgac atgtagaatc tgatggcctt gttttcgacc cagcgcaaat
    16921 cacaagtcga acagctagag gtgttgcagt gccacacgga gatcattacc acttcatccc
    16981 ttactctcaa atgtctgaat tggaagaacg aatcgctcgt attattcccc ttcgttatcg
    17041 ttcaaaccat tgggtaccag attcaaggcc agaacaacca agtccacaac cgactccgga
    17101 acctagtcca ggcccgcaac ctgcaccaaa tcttaaaata gactcaaatt cttctttggt
    17161 tagtcagctg gtacgaaaag ttggggaagg atatgtattc gaagaaaagg gcatctctcg
    17221 ttatgtcttt gcgaaagatt taccatctga aactgttaaa aatcttgaaa gtaagttatc
    17281 aaaacaagag agtgtttcac acactttaac tgctaaaaaa gaaaatgttg ctcctcgtga
    17341 ccaagaattt tatgataaag catataatct gttaactgag gctcataaag ccttgtttga
    17401 aaataagggt cgtaattctg atttccaagc cttagacaaa ttattagaac gcttgaatga
    17461 tgaatcgact aataaagaaa aattggtaga tgatttattg gcattcctag caccaattac
    17521 ccatccagag cgacttggca agccaaattc tcaaattgag tatactgaag acgaagttcg
    17581 tattgctcaa ttagctgata agtatacaac gtcagatggt tacatttttg atgaacatga
    17641 tataatcagt gatgaaggag atgcatatgt aacgcctcat atgggccata gtcactggat
    17701 tggaaaagat agcctttctg ataaggaaaa agttgcagct caagcctata ctaaagaaaa
    17761 aggtatccta cctccatctc cagacgcaga tgttaaagca aatccaactg gagatagtgc
    17821 agcagctatt tacaatcgtg tgaaagggga aaaacgaatt ccactcgttc gacttccata
    17881 tatggttgag catacagttg aggttaaaaa cggtaatttg attattcctc ataaggatca
    17941 ttaccataat attaaatttg cttggtttga tgatcacaca tacaaagctc caaatggcta
    18001 taccttggaa gatttgtttg cgacgattaa gtactacgta gaacaccctg acgaacgtcc
    18061 acattctaat gatggatggg gcaatgccag tgagcatgtg ttaggcaaga aagaccacag
    18121 tgaagatcca aataagaact tcaaagcgga tgaagagcca gtagaggaaa cacctgctga
    18181 gccagaagtc cctcaagtag agactgaaaa agtagaagcc caactcaaag aagcagaagt
    18241 tttgcttgcg aaagtaacgg attctagtct gaaagccaat gcaacagaaa ctctagctgg
    18301 tttacgaaat aatttgactc ttcaaattat ggataacaat agtatcatgg cagaagcaga
    18361 aaaattactt gcgttgttaa aaggaagtaa tccttcatct gtaagtaagg aaaaaataaa
    18421 ctaatgaaaa atgaaagtct cgataaagag gctttcattt ttattatgta tatatgtaaa
    18481 attcttgaca agcaatatta aaaagagtaa actattaact agttaattaa ccggtttatt
    18541 actttatagt gaatcaaata tacttaagaa aagaggaaag aatgaaaatc aataaaaaat
    18601 atctagctgg gtcagtagct acacttgttt taagtgtctg tgcttatgaa ctaggtttgc
    18661 atcaagctca aactgtaaaa gaaaataatc gtgtttccta tatagatgga aaacaagcga
    18721 cgcaaaaaac ggagaatttg actcctgatg aggttagcaa gcgtgaagga atcaatgccg
    18781 aacaaatcgt catcaagata acagaccaag gctatgtcac ttcacatggg gaccactatc
    18841 attattacaa tggtaaggtt ccttatgacg ctatcatcag tgaagaattg ctgatgaagg
    18901 atccaaacta ccagctaaag gacgaggata ttatcagtga aatcaagggt ggttatgtga
    18961 ttaaggtaga tggaaaatac tatgtttacc ttaaggatgc agctcatgcg gataatgtcc
    19021 gtacaaaaga agaaatcaat cggcaaaaac aagaacatag tcagcatcgt gaaggaggga
    19081 cttcaacaaa cgatggtgcg gtagcctttg cacgttcaca aggacgctat actacagatg
    19141 atggttatat ctttaatgct tctgatatca ttgaggacac gggtgatgct tatatcgttc
    19201 ctcacggcga ccattaccat tacattccta agaatgagtt atcagctagc gagttagctg
    19261 ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa ttcaagaacc tatcgccgac
    19321 aaaatagcga taacacttca agaacaaact ggctaccttc tgtaagcaat ccaggaacta
    19381 caaatactaa cacaagcaac aacagcaaca ctaacagtca agcaagtcaa agtaatgaca
    19441 ttgatagtct cttgaaacag ctctacaaac tgcctttgag tcaacgccat gtagaatctg
    19501 atggccttgt tttcgaccca gcgcaaatca caagtcgaac cgccagaggt gtagctgtcc
    19561 ctcatggtaa ccattaccac tttatccctt atgaacaaat gtctgaattg gaaaaacgaa
    19621 ttgctcgtat tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag
    19681 aacaaccaag tccacaatcg actccggaac ctagtccaag tctgcaacct gcaccaaatc
    19741 ctcaaccagc tccaagcaat ccaattgatg agaaattggt caaagaagct gttcgaaaag
    19801 taggcgatgg ttatgtcttt gaggagaatg gagtttctcg ttatatccca gccaaggatc
    19861 tttcagcaga aacagcagca ggcattgata gcaaactggc caagcaggaa agtttatcgc
    19921 ataagctagg agctaagaaa actgacctcc catctagtga tagagaattt tacaataaga
    19981 cttatgactt actagcaaga attcaccaag atttacttga taataaaggt cgacaagttg
    20041 attttgaggc tttggataac ctgttggaac gactcaagga tgtctcaagt gataaagtca
    20101 agttagtgga tgatattctt gccttcttag ctccgattcg tcatccagaa cgtttagg
//
LOCUS       DAVBED010000042        20082 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBED010000042 DAVBED010000000
VERSION     DAVBED010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.042"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..641)
                     /locus_tag="VQ547_001486"
     CDS             complement(<1..641)
                     /locus_tag="VQ547_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2543323.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKL"
     gene            complement(750..1268)
                     /locus_tag="VQ547_001487"
     CDS             complement(750..1268)
                     /locus_tag="VQ547_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2543324.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1495..2364)
                     /gene="rsmI"
                     /locus_tag="VQ547_001488"
     CDS             complement(1495..2364)
                     /gene="rsmI"
                     /locus_tag="VQ547_001488"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2543325.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2367..2684)
                     /gene="yabA"
                     /locus_tag="VQ547_001489"
     CDS             complement(2367..2684)
                     /gene="yabA"
                     /locus_tag="VQ547_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2543326.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2724..3614)
                     /locus_tag="VQ547_001490"
     CDS             complement(2724..3614)
                     /locus_tag="VQ547_001490"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2543327.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3611..4249)
                     /locus_tag="VQ547_001491"
     CDS             complement(3611..4249)
                     /locus_tag="VQ547_001491"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2543328.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4469..5266)
                     /gene="proC"
                     /locus_tag="VQ547_001492"
     CDS             complement(4469..5266)
                     /gene="proC"
                     /locus_tag="VQ547_001492"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2543329.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5270..6532)
                     /locus_tag="VQ547_001493"
     CDS             complement(5270..6532)
                     /locus_tag="VQ547_001493"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2543330.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6542..7672)
                     /locus_tag="VQ547_001494"
     CDS             complement(6542..7672)
                     /locus_tag="VQ547_001494"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2543331.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7755..9635)
                     /gene="cbpE"
                     /locus_tag="VQ547_001495"
                     /gene_synonym="pce"
     CDS             complement(7755..9635)
                     /gene="cbpE"
                     /locus_tag="VQ547_001495"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2543332.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9638..10525)
                     /locus_tag="VQ547_001496"
     CDS             complement(9638..10525)
                     /locus_tag="VQ547_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2543333.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10515..10976)
                     /locus_tag="VQ547_001497"
     CDS             complement(10515..10976)
                     /locus_tag="VQ547_001497"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2543334.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10973..11881)
                     /locus_tag="VQ547_001498"
     CDS             complement(10973..11881)
                     /locus_tag="VQ547_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2543335.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11874..12071
                     /locus_tag="VQ547_001499"
     CDS             11874..12071
                     /locus_tag="VQ547_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543336.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12123..12794)
                     /locus_tag="VQ547_001500"
     CDS             complement(12123..12794)
                     /locus_tag="VQ547_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543337.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12848..13069)
                     /locus_tag="VQ547_001501"
     CDS             complement(12848..13069)
                     /locus_tag="VQ547_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2543338.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13341..14150
                     /locus_tag="VQ547_001502"
     CDS             13341..14150
                     /locus_tag="VQ547_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2543339.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14331..15206)
                     /gene="aguB"
                     /locus_tag="VQ547_001503"
     CDS             complement(14331..15206)
                     /gene="aguB"
                     /locus_tag="VQ547_001503"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2543340.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15216..16301)
                     /gene="aguA"
                     /locus_tag="VQ547_001504"
     CDS             complement(15216..16301)
                     /gene="aguA"
                     /locus_tag="VQ547_001504"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2543341.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16298..17425)
                     /gene="nspC"
                     /locus_tag="VQ547_001505"
     CDS             complement(16298..17425)
                     /gene="nspC"
                     /locus_tag="VQ547_001505"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2543342.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17425..18684)
                     /locus_tag="VQ547_001506"
     CDS             complement(17425..18684)
                     /locus_tag="VQ547_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2543343.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18681..19541)
                     /gene="speE"
                     /locus_tag="VQ547_001507"
     CDS             complement(18681..19541)
                     /gene="speE"
                     /locus_tag="VQ547_001507"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2543344.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19797..20082
                     /locus_tag="VQ547_001508"
                     /pseudo
     CDS             19797..20082
                     /locus_tag="VQ547_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5828 a         4616 c         3568 g         6070 t
ORIGIN      
        1 tctagttttg caggaagtct aatgtaattc tcaagctgtg agttcattat gatttgtaaa
       61 tccgatatat cttcagcagc taaaaacaca ttttgaaatg ttccaagtcc gttttcacca
      121 aaactatatt ctctcttact atacttactc ttattattct ctatatagtt agagtcaagg
      181 ttcttaacct cttgaagttc attttcttta cttctgaggt taaaatcttt tacttctgaa
      241 gttaagtttt ttgacttctg taagtcattt tcttttacct gaaatatact cataaagtct
      301 ttaacataaa tgatgttcgg cttaccaagt ccaagcctta ctctttcgat cagtcctatt
      361 ccttttttta catcaagctc atctaatgtt tttatggcag ttggctttga gatatttctt
      421 cttttcataa tttcttcgac agtaaaatag ataaatactc tgccttcctt gtctatccag
      481 ttattcttaa atgacattcc tgtctgttta agaagtatgg aataaaggat aattgcttct
      541 gctgataagc cccgaaattc ttctctatca actaatatct ccggtacttt taagaagtta
      601 aatctttccg cttctctgtt ataaaaatat tcaaagtcca tgcaagatca cctcccttct
      661 taaaaatttg caaagaaaaa gacgatagtt tttcttctat cgcctttggt aaccattttt
      721 atgaaatttt ttaaagttaa aaatataatt tataatacta tcttcttcca ttttctgatt
      781 ttagttctga aagttccaaa aggtgcaacc gtatttacat gaataaactt atacacttcc
      841 caagtcgctg ttttagtcgc ttcatcagcc cactttctca tatgcggttc aaataattct
      901 tcctcactca acgaatcaat cattgcagag atagaattaa tattttcatt taattttgct
      961 ttcaactctt gcagagataa atgagcgtag gtatctgtga accactgata taattcacca
     1021 agttgattcc atttaaattt atccgatggt gtttttactt gaagcccctt tctttcatct
     1081 tcttcccatt taagaaccaa gttggtccaa ccaacctgat aagcaaggtt ttctgctgga
     1141 gttctgtcaa cttcatcagc tctcttatct tttaaatttt ctggaatatt atcaaattct
     1201 aaaatatatt tctcaaatgt tttctctatc tcagctttta gttcttcttt attttcgtat
     1261 gttcgcaaaa aatcaccttc tttctgattt atcaatcctt tgatttaaaa tgaccttatt
     1321 tttctattta taccttctaa gaacgctata actgctgctc caaacatcgg tattccgtat
     1381 gggcttaata aaaaacttaa taccaaagct tctataccaa gtgatacatc tttatattat
     1441 catcactaat taagttaaac agaaacagac agaattatta catcctgtct ccctttattg
     1501 tttttcttcc caatcgtggt aggcagcgta gagttgactc ttattccact ggtaaatctt
     1561 agctacttcc ttaatagctt gatttttctt catgccttgc tggatacggg cttggatttc
     1621 taagaacaag tcctcctcgt ctttttcctc cacatcctga ctggcacctt caacaataag
     1681 aaggcattcg cccttgagtg gcgtttcagc gatgctttcc agtaattcag aaattgtacc
     1741 tcgttggtat tcttcataga ttttggtcaa ttccctgacc aaaacaaccg agcggtcacc
     1801 gtagacttct aacatatttt ccaacgtgtc tgctacacga tgaggtgatt cataaaaaat
     1861 ctgtgtttca ggataatctt ttttagagcc aaaaaattgc ttctgttgac ctgattttct
     1921 cggtaaaaaa ccgtaaaaga tatgtggctg tggcgctaaa ccactggcaa tcaaggcaga
     1981 aattcctgca gaggtacctg gaacagtcac aactgcaatt tcttcctcaa tagctgcctt
     2041 aactaaatca tgaccagggt ctgaaatgct aggcaaaccg gcatcagaga cctgagcaat
     2101 actttgccct gctttcaaga aaccaatcaa atcaggaatt ttttccttgg cattgtgctc
     2161 atgaaaactg atctgcttgg tggaaatgtc aaaatgcttg agcaaaagcc ctgtattgcg
     2221 cgtatcctca gcagcaatcc agtccacttc tttcaaggtc tggatagcac gaaaagtcat
     2281 atcatctaga ttgccaatcg gcgttgccac tagatacagc ttgccatagg gagactgccc
     2341 cttaaaactt ttttgaattt gcatgcttac tccctgtata acaactcatc acagaacata
     2401 cattcttcgt cctgctctcg acgttgtcca taaaaatcat tacatacgtg aaatccatca
     2461 cggtaaatac gacggacact ttcgcgaaca tgcttggcct tgacgggagc gtctgcttcc
     2521 acctcaccca agcgttctcg caacttacta ttttccaagc gaagagctgt attttcttct
     2581 accaagctct tgagattttt cttgatggct tccacatcgg ctaaagttac caataattgt
     2641 tgggaaaaat catccagcgc gtcaaataat tcttttttgt ccataaaaca gccctttcct
     2701 ttctttatca ttcatttttg agtttatatt tctttcaaga ccagatattc catggcattt
     2761 tgaaagctga cattagcttg ccacattttt ctagcttcta gtaaatcttg tagaatcact
     2821 cttactctta cctgcaagag gtcctgccca cagagaactt caagaatccg taaaacctga
     2881 tcctgttttt ccttatcatc tgccaagttg gctaatttgg caacctgtag ataactttct
     2941 tttttcttag ctactaacca agtcagcagg cgttcacttt catcgaccaa ggtccaaaaa
     3001 cttgcctgat tagccaactt ttctgcttca gctcgcgatt gactaaactt agctaaaaga
     3061 gtcgcttttt tcttaacaag tcccatttgt tctaagagta agataagttt ttcttcttgc
     3121 tttttaaagt ggaagatctg agtccgactt cggattgtcg gtaacatctt ttcctcatcg
     3181 ctagtcaaga agaaaatata aacttcactc tggggttctt cgatgacctt gagcagagaa
     3241 ttggctgcgt tgggatgcat tttatccgct tgctcgatga taaagacctg ttgctggctt
     3301 tcaatccctg cttgagaaaa ctgtcccacc aattcccgaa tacgttctgt cttgatgacc
     3361 tgattgactg gcttaatcaa ggtgacatct ggaaactctt cctgttcaat cagcttgcaa
     3421 cttcggcatt tctcacatgg taagacgcca actttatccg tacaaaagag gctcttagct
     3481 aaaaattgcg ccatttccaa gcttccaaag aaacctgaaa agagataggc gtgattgagc
     3541 tggtcttgtt ctaagatacg gacaaaacgg tcaaactgag ctggttgcca agcctttagt
     3601 tgatcttgtt tcatttggcc aagcccattc cgtcaaacaa gacagccttg gtagtttcca
     3661 caacttgctc caaagggaga ctagcatcaa tcttgacaat gcgatttccc tctttatcca
     3721 gaagagaaag gtagccttga cgaacttttt tatgcaagtc caacccttcc aaatccaaac
     3781 gattaacctc gcggtcacta ttagcagcaa tacgagccag cccttcttcc acctcgatgt
     3841 caaaatagag tgtcaaatcg ggtttgaggc catctgtcgc aaactgattg agccagtcaa
     3901 tggcttcaat atctaagcca cgaccaaatc cctgataggc aacagaacta tcgataaaac
     3961 gatccatgat gaccaacttg ccagcttcaa gggctggaag aactttttcc accaaatgct
     4021 gtctgcgact ggcaatatag agaagtagct ctgttttagc atccatctga gtatgacttg
     4081 gatccaaaat cacttcccga atcttctccc caatcaagac tccgccaggt tcacgggtcg
     4141 tcagcacctt tactcctttt tcctctaaaa ttggtagcag agcctctaaa acactggtct
     4201 tgcctgctcc ctctggtccc tcaagagaga ctaaaaatcc ttttgacatg tctaactcat
     4261 ttctttttta ctacttctat tctatcaaaa aaataggggt ttgtgacaat ctttttgtct
     4321 tctcatttca tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgtac
     4381 ttgagtacgg caaggtgaag ctgacgcagt ttgaatttga ttttcgaaga gtatcagcca
     4441 ccataaaaga ggcagataaa actacctctt atttacctag ttcttgtgtt cgtttatagg
     4501 cttgatgaac tgcctccatg actgtgcctc gaaaagcatg cgcttctagg cttgctacgc
     4561 cagcaatagt cgaaccgcct ggactacaaa cttgatcttt caaaactcca ggatgttgct
     4621 ggctttctag gaccaattgc ccagctccta ccacagtttg ggctgccatt ttcaaggctg
     4681 tttctcgtgg taatcccgtc tgaacacctg catctgccaa ggcctcaata aagagataga
     4741 caaaggctgg tccacaacct gcaagacctg tcgctgcatt gattaagctt tctcctaatt
     4801 caaccaagag accagccttg gctaaaagct gacaaaagat ctcactgtcc tcagccctgc
     4861 aattaggaga caaggcataa ctaatcactc cttgcccgat agaagcaggg gtattaggca
     4921 tcatacgaat aattcggtgt tggcttggga taagacttgc tagtttttct aaggtcaatc
     4981 cagctgccat cgaaatcaaa agaagacttt ctcttttttc aaggatggtc tggtattgag
     5041 aaagcagttc agaaaactga gcaggcttaa cacctagaaa aatcacatct gcttcttcga
     5101 atatttcttc attgttagaa gtctgaccac cgaagttagc gatgaaagca tccaccttga
     5161 cttgactacg attggcaagg agaatctcat ctgacggtct agcctgcaag acagacttgg
     5221 ttaaactagc acccatattc cccaaaccga taaatccaat cttcatctct tactccctta
     5281 tctgtccatc accagtgacc acatacttgt agctagtcaa ttccttcaag cccataggac
     5341 cacgcgcgtg caatttctga gtagaaatcc ccatttcaca accaagacca aattgtcctc
     5401 catctgtgaa acgagttgag gcattaacat acaccgctgc agagtccact tgatctgtaa
     5461 agtatgctgc agcttcagca ttttccgtca caatggcatc cgaatgatgg gtactgtggg
     5521 attcaatatg cgcaaccgct tcttctaaac tgctcacaac cttaacagct agaatatagt
     5581 ctaaaaactc ggtatcaaag tcttgtgctt gagcagcttg acctgaaaca aactggcttg
     5641 ctttgctatc taggcggaat tgaattggtt ccaacccagc ttcttttcga tctgcaacca
     5701 acacttgctc caagcgagga aggaagctta ctgctttgtt ttcatgaacc agcagaacct
     5761 ccatggcatt acaaacagaa ggacgactgg ttttagcatt gttgatgata gacagcgcct
     5821 tgtcttcgtc tgcatcctta tccacataga catggacaat cccagttcct gtctcgataa
     5881 caggtacaat cgcattctca accactgcat tgatcaagcc agctcctcca cgaggaatga
     5941 gaaggtctag atagcccttg gccttcatca tagcataact actttcacgg ctagtatcct
     6001 ccaccagttg aatcacattt ggatgaatag tagtcgtctc caagcccttc ttcaaggctg
     6061 tgacaatggc atgggttgtt tgataggcat ccttaccact acgaagaaca accgcatttc
     6121 cactcttaag agtcaaagca gccgcatcag acgtcacatt tggacggctt tcatagataa
     6181 taccgatgac acccatagct acacgttttt ttgtgataac caaaccattt tcaagctgac
     6241 ttgtttctaa aacttcaccg attggatctg gtaaggcaac cacttcacga attcctcttg
     6301 ccatcgcttc tatacgatct gcatccaaat aaagacgatc caacatcaca tctgagattt
     6361 tccccttagc cgctgccata tcgagggcat tagccgctaa aatttcctca gtagcagcca
     6421 ctaagtgatc agccatggct agcaaggctt ggtttttcac ttcttcacta gctgtgttaa
     6481 tcgatttttt aacagcctgt acctgttcaa attgttcttg tctactcacc atagtttacc
     6541 tctaaaattc tgtaaaaagt agttggattt caggagtaat ggaaatccag tcgtcacggt
     6601 aaatcaagac acccttggct ttttgaaaac gcaacatatc ctccaaagca gatgctccaa
     6661 attgcacgcg tccttttcca agtgattttc cactttcctt atcaaatact gtcacgatat
     6721 caccgtaaga aaagactcct tctgcttcaa cgataccaga taagagaaga ctctttccat
     6781 gttgagagag agcttccgca gcccctttat caacccaaat agaaccttga ctctgagcat
     6841 agaaggcaag ccattgtttc tgggtacgaa gccccttctc ttgagcaaca aagtaagaac
     6901 catcctcggt ctcctctgcc gcctcaacca tggaatctga tttcaaggat gagcagatat
     6961 aaacaggaac tcctgattcc gtcgcgatag ttgcagcctt gattttggtt aacatacccc
     7021 cagttccgtt tgacgaacca gctccaccag ccatatcaat aatctcacga ttgatggtct
     7081 cgattctctc caagcgtttg gctcttggat ctgaattagg atttccagta tagagaccgt
     7141 ccacatctgt caagaaaact aaaaggtctg cttggaccat cgccgctact tgagcactta
     7201 gagtgtcatt gtccccaacc ttgagctcat caataacgac actatcattc tcattgatga
     7261 taggaattgc cccacggttg agcaaaaccg acaaagcctg atgggcattt ttataacgac
     7321 gcttatccac aaagtcatct tgggtcagca agatttgtgc agaaacgatt tgacgcaaga
     7381 gaagattggt cgtatattct tccaacaaaa gtccctgccc taccgctgct gaagcctgtt
     7441 tatcagcaat tttagtcgga cgctttttaa atcctaaggc tccaaaacca gccgcaatgg
     7501 cacctgaaga caccaaaatc aactcatgac cagcctcgtg cagcatagcc aactgctggg
     7561 taatatcctt taccttacta cgtgataaac ttccatcctc atttgtcaga gaagaagtgc
     7621 ccaccttaaa gacaatccgt ttgtatttca tagtctcact ccgattattc atatttatcc
     7681 attataacat gaataacagg aaatagaaaa gagttgatag gaaaaagaag gccctaaaac
     7741 cttcttttct actactattc tgattccgat ttgtttacac tcgtttcaga gctttgtgaa
     7801 gttgaggatg tcaaatcttg actagttgaa gaatttgtaa cactttcatg ttgactcgtt
     7861 tctttatttt caagatcctt tttcactact tctttggatt cttttatttc tgaatgactt
     7921 gtagttttaa ttgtagcaga tttctcgatc ggaacatcca ctaaccaggc accacttgaa
     7981 tccacagtat agccttctgg tgtcttacca ttcacaagta attgaccatt ttctttcaag
     8041 aagtaccatt tatccttgtc tttaatccaa cctatagctc gtgaaccacc tgtcttgtag
     8101 aaataccaat catttgcctt tttaagccag ccttgcttca tagctcctga ttcttctaga
     8161 tagtaatgat gtccagcaac ttctatctca cctgtcttca tgataccagt agaatccata
     8221 tagtaccagg cttctttatc ttttacccag cccgttttca tttcccctga tggagcaaag
     8281 taataccatt gccccttata ttgaagccaa cctgtcttca tagagccatc aacatccaaa
     8341 taataccact gctctttatc ttgaacccaa ccaatttcca tctgattttc tttgttaaaa
     8401 taataccaga ttccatcaat tttcttccaa tttttagcag aagcaccaga gtctgtcaaa
     8461 tagaaccaat gattgttcca ttttttccat tgattctgta acaagatacc cgtttggtta
     8521 aagtaatacc attcaccttc gatttcattc caaccgacag catactctcc tgtagaatca
     8581 ggcgcttgat accaccagtt cccatatgca ctcttatgcc aaccagcttg aaaacttgga
     8641 atcggcttgt aggatgttga aatattgaca aaaccgtctt ttcgaatatc aaaaactgtt
     8701 gcatcatagt ctttgctggc tgcgttgatt ctctcaattc ctcgttcttt gagccaatta
     8761 acatactcac tatcaacacc atttttccaa ggtagactat ccgaagtttg aacaatcaaa
     8821 ctcggactca aatttttaat gaaatccttg gtatttgatt tgttggtatc atggtgatga
     8881 ttaaacttca tcaaatcaac ttttccaatg agaggaccat acttgtcttc tgctccatga
     8941 acattatcta aatcgccccc aaggtaaatt ttcttgccat tgactttcac cacgctaatc
     9001 aaggaattgg aattgtcatc ccaaattttc tttaattcac ccgatgaatc agtttcattt
     9061 tcataattat agagctgaat atccatgtcc ccaaactgaa aatgagcatc cccttgtgtg
     9121 atattttgaa taactgaaac acctttttct gcagcagtct gtaaaacctt atcatagcca
     9181 tacagattat cccatagacg ttcagaatta gtaatacgac tatcactata tttcttaaga
     9241 tagactcggt caactggata ggtagacagt aattcatcaa catttccaat atgatcactg
     9301 tgggtatggg tcaccaaaat aaaatcaagt ttttggacac ccaattcctt caaacgacga
     9361 aagacacggt ctgttagaac atgcttataa gacgtttcaa ttccttctct ccatggataa
     9421 cgagaatcac ttccatctgg gaaatcataa tcttctcctg tatccaccat ggcaaaatgt
     9481 ccattgcttt caagaataat cgcatcactg ccaccttctt gaacattgat aaagtggatt
     9541 ttatttcctg aactttcttg agcctgaaca ttcccatacc atgacaaacc taaaaaagcg
     9601 cctacaagtg ctaaactagt taatttcttt ttcattctta ctttctcaat ctctccaagg
     9661 tttccttaaa aatctctggg atatctgctt taaattccaa ggtcttacct gttctcggat
     9721 gagtaaaacc taaagtcttg gcatgaagaa attgtccatg tcctttcaaa gtcttgcgag
     9781 gaccatagac ctcatcacca gcgactggat ggccgatata agccatgtgg acacggattt
     9841 gatgagtgcg ccctgtctcc agttgcaact ctactaagct ataatcgcca aagcgttcca
     9901 agacgtgaaa acgcgtcact gcaggcttcc ctttagcagt tacagcctgt ttcttacggt
     9961 ctttttcact ccggccaatc ggcgcttcaa ttacaccacg atcattaggc agatttccat
    10021 gaacaatcgc ccaatatttg cggagagact ttttatcttt gagttcttgg gcaagtacta
    10081 gatgcgcatc atcgttttta gcaatcatga gaagacctga cgtatcctta tcaatacggt
    10141 gaacaatccc tggacgcaga accccattga tacccgacaa gtccttaata tgatacatga
    10201 gggcatttac tagggttcca ctggtatgac cagcactcgg gtgcacaacc attccctgag
    10261 gtttgttaac gacagccaca tcctcatctt ggtagactat ttctagcgga agatcctcag
    10321 ccacatactc taatacctct ggttctggca catggtaagt gacgacatca ccctcttgga
    10381 ctgtgtattt agctttcttg acttgaccat tgaccaagac ctggcctgat ttaatttgtt
    10441 cattcgcgag actacgtgat aattctgaca aatctgacaa agccttatcc aaacgcagac
    10501 caccagtttc aattttaatt tccatttatt tcctctttta gcattgcaat caataaaata
    10561 atcactccaa ccgtcagata gctatctgcc acattgaaaa ttgcaaagtt gataaagtca
    10621 aggtggaaca tatccacaac aaagccctga ctgaccctgt caataaagtt tccaagacca
    10681 cccgcgatta ttagagtcaa acccaagaac atccagaatg agtcctccat gtgtttatgt
    10741 aaataccaaa tggcacctat cacgacaacc agagtaatga cagcgaataa cagctgctga
    10801 tcttgtaaga tagaaaaggc tgcacctcga ttttgcaggt aggtcaagct aacgaaattg
    10861 ggaatccagg agcgcacttc acccagtgga atctgctgga cgatatagga tttgaccaac
    10921 tgatccagcc caattaaaag cagtacaatg actgccacta ttgctctttt tttcatgatt
    10981 tcctcttttg atcaaaatat tcttgcatga cttctacgaa gagagtccca gcttgactaa
    11041 gctccacttc ttcacgttta acatagacca tgcggttatc taggttatcc ttgagacgaa
    11101 taactgtaat gccattaaca ctgtcactat ctaaaaatcc agaacctgtc gcataggcgt
    11161 ccgtccgctc caaaatacca ttcaaggtgg cacggtctgt cacattaaac atctgtgagc
    11221 tagcgctggt atcgacaaag ttctctgaat aataaaggta ctcgtctttc tcttgagtga
    11281 aacgaaccgt tggtaaatcc gctaaatcct ccatgactaa ttcctctttc tgggctaaag
    11341 gatgaccctc acagagataa atatgggtat ggaaaggaat caattcgatg acctccagac
    11401 ctaacttttc aacccgttgc ataatcccct ttttattttg attgttgagg tagataatcc
    11461 caatctcact atgcccttgc gccacttcat ctaatatttg aacagtagtt gattcaaaaa
    11521 tacggaagtt cttatagtca ggatagcgct ctgaaaaggc cgtaatagtt ggtggtaaga
    11581 agtcatagtg ctggctagca acggaaaatt catctttttc ttcttcagga ttggcatact
    11641 gattttgaaa aatatcaaat cctttaacca attcttgcgc tttttcataa aattccatcc
    11701 cacgacgggt caagaaagtc cctgagctgg tccgacggaa aatcttaaag cccaactctt
    11761 tttccaaatc acgaacagaa atagacagac tcggctgact aacatacatc ttttcagcag
    11821 cttcacgaaa agtaccacta ttggcaatag ccacaacata gcgtaattgt tgaatgttca
    11881 tcttctaccc ccaacttctt tatcttttca ttataccata ttttagaagt tttccaaaaa
    11941 ggaaaaaaga acatcctatt cttcttaact atcttcacta tctgcctttc tcacgccaat
    12001 cttattttca aaatcaattc aaaaaaataa gtggctacac accacttcag tatcggaaag
    12061 aaaaacgttg actatttgtg aaaaaagaaa atgccggaaa attccgacat ttttttagta
    12121 agctaacttc ctgaaaatag gagtaaccaa acatcccaga aggcagtgat attgatgaga
    12181 atatgaacta gtattggata gtagagattt ttagtcatgc gatacaatag agctaaaatc
    12241 agacctccac tagcataaat gaaaaaagca agaggagtta aagcaaaatt gatatgaata
    12301 taaccgaaaa taatagcaga aagcaaaaca tctccgtacc aaggtgagtt tttgaaaaag
    12361 gttgtcataa gcacacctcg ataaatcaat tcctcagcaa taggggcgat gaagcaaacg
    12421 atgagcaaga aataagggaa ctcctgtctc cccatcattt ctaccgtttc attcaaagaa
    12481 atctgatttg aagacaggga tatgaaatac gaaaagagga agtcagacat atatgaaatg
    12541 atgtagccca gtaaaaggta gatgaagtac ctcagctgcc acttgaaatg aaaaattttc
    12601 tttcctgcaa aaaccagtag atagatgacc gctaagaaaa gaactccgct ctccatcaaa
    12661 agcagaatct gaaaaaattc acgacttgct ggtagatagg gctttgcgag gtgattgaaa
    12721 actctccaaa accaagttga tttgtaaaaa attaaggaca atgctagtaa aatttgaata
    12781 gcccgttttt tcatattaaa ttctctgctt tctccactta tttcttcata ttactaataa
    12841 attttactta aaatctcgca gcacttcctt tgcaaagatg attgcctcct ccaatatatc
    12901 ctaaatcata ggtgcctctg ggacaaaatc catgaaccgg cagagttaat actggttcta
    12961 tttcccaatc gtacctacca ttaggatttt taccatatga atctgctcca ccttgtatca
    13021 gctctaattc ttcatttgtt agatttatat tttttgtcat taaaatcatg atatatttcc
    13081 tccattattc ttcagattag ttgagtaatc tgatactcat acctacttac aaaaaaacta
    13141 ttatattaag ttggtttttt aatttgtcta gttgcaacat tgacaaacat agtatagcat
    13201 atctttgcga aatatcctct tcaaatcatg aattgtcatc aaaacatctt aaactataaa
    13261 atcaattagt ctcaagcttt ctatcaattt cttctccaaa atatgctata ataatagcaa
    13321 aagataaaga aggaagacct atgattaaac tactagcctt ggatatggac ggcaccctcc
    13381 tcaatgaagc caaggaaatc ccacaagctc acattactgc tattcacaaa gccattgaaa
    13441 aaggtgtcaa actggttctc tgtacgggtc gccccctttt cggtgtcctc ccctactaca
    13501 aaaaactggg actcgacctc cagaatgagt atgtgattgt taacaacggt tgttcaactc
    13561 accagactag cgactggggc ttggttgact ggcaagaact tagtccagct gacatcgaat
    13621 acctctatga ccttgctgaa aagagtgatg ttcagttgac actttttgac gagtcacatt
    13681 attttgttct cggtggaaag cccaatcaag ttattgaaaa tgatgctaaa ctagtatttt
    13741 cagacctgac tgaaatttct cttgaggaag cgactagtgg aaagttccgg atgttccaag
    13801 gtatgttttt aggaacaaaa gaacaaacag acgattttga gcagcgtttt gctgaagagc
    13861 tttgccaacg attcagtgga gttcgttcgc agcctgtcat ttatgaagca atgccacttg
    13921 gaacgacaaa ggctactgct ctttcacgac tagctgagat tttgaagatt gattcctcag
    13981 agattatggc catgggcgat gctaataacg atatcgaaat gctccagttt gcagggcttg
    14041 ggattgcaat gggaaatgcc agcgattatg tcaaatctct tgcggatgcc gttacctcaa
    14101 gcaacgaaga agacggcgtt gcgcgtgcta ttgagaaata tattctataa aaaagaaaag
    14161 caaatagaca gaagttactg ctatttgctt ttttgctaat attttaaaat acggactaat
    14221 caatagagaa gaatagcgaa tcataaaaat cgatttacta gatgccatag tatcttatag
    14281 ttgctaataa gaagttagtc tagcagaatg aatctctcat ttctcccaca ctaatctgta
    14341 atttgtctat acatttctgg tcttctatct cgaaacaagc cccagtttag gcgttcactt
    14401 gctcccttgt ctaggttata agtagctaac agaacagctt cttcttgtct ttcagctcgt
    14461 tctagaatag ctcctgtttc atccgtcata aaggaggaac cgtagaagtc aagactggaa
    14521 ctctgtccgc cattttcctc actaggagta acctcctcta aaccataacg attggctgcg
    14581 atgactggaa caatattcgc tgctgcgtgc ccttgcatag tacgttgcca gtgaccacaa
    14641 ctatctgtat ccaaaattgg ctctgaaccg atagctgtag gataaaagag caattcagca
    14701 ccattcaatg caagacagcg cgctgtttca gggaaccatt gatcccaaca gataccgata
    14761 ccaatcttag catagcgagt attccagacc ttgaaaccag tgttaccagg cgtgaaatag
    14821 aatttttctt gataataatg gtcatctggt atatgggtct ttcgataaac gcccagcact
    14881 tccccatctg catcaatgac ggcaatagag ttatacaaga cattaccatc tttttcatag
    14941 aaactgattg gtaaaacaac ttgtagttcc ttagcaagca acttaaaatg ctgaatggca
    15001 gtattttccg ctacagattg ggcatactgg tagtagtcat actgacgttc ctgacagaaa
    15061 tagggatgtt caaacaactc gggcaagaga ataatttggg ctccttgctc agcagcctga
    15121 cgtactaaac gctctgcggt ttggatattt gttgccacat ccttagcgca ttgcatctga
    15181 atggttgcaa ctcttacatt tctcatcttt ttctcctatt ctggaatttg ttgggtgata
    15241 cagtggatat tgccaccacc taagagaata tctctggctg gtattccgac aactttacgg
    15301 tctgggaaac acttgctgag gatatctaag gccacttggt cgtttacatc ctcaaactgt
    15361 ggaaccaaga cagccttgtt ggcgatataa aagtttacgt aggaagctgc tagtcgttca
    15421 cctgcgtatc gctcttcttc tccttcttca tagatgtagc ctggcaaatc ttcttctgtc
    15481 acaacttgtc gaactgcagg gataggcaat ttatgaatgg tgaagtgaca accttttgca
    15541 tctgtttcct gttctaagag ttcgagatct gcttttgaca tggcatactg gggatcattt
    15601 tcgtcatctg tccaagccaa aacaacctca gcaggaccaa caaaggcaac aacattatcg
    15661 acgtgttcat tggtttcatc ctgataaata ccataaggaa gccaaataac tttttcagca
    15721 ccaagacttt ctaataatgt gttttcaatc tcctctttag tcaagttagg attgcgacca
    15781 ggactaagca agcaactttc agttacgaga atagttcctt gaccatcgct atggattgcg
    15841 cctccttcca gtacaaaagg tttagcatca tagacaggcc tttccaaggc ctcagcaaaa
    15901 cgactggcta cttggtcatc ctcttcataa tcttgataaa gaccatcata ggtgcctccc
    15961 caagcattaa aggcccaatc cacggctaat ttcttacctt tatcattgac gagaatggtt
    16021 gggccagtat cacgcgccca ggcatcattg gtgggaatgt ctaaataaac aaccttgtct
    16081 ccaagatagg attgggcttc agatagatag gcctgctcca ccaaaagata gactctttcc
    16141 ccttctgcta tggtctcgat gatctgagta aatgctcttt tagcagcctt tccttgaaaa
    16201 ggccatgatc ctggtcgagt cggccatatc atgagggtac catgatgggg ttcgtactct
    16261 gctggcatgt gatagcctaa tttttttgga ctgtccatca tgataatctc cctttaaagt
    16321 cttgatagcc aaaagctttg agtaagctac agtctccctg ttcgtccatg agatagagac
    16381 ttggcaatcc aataccatta aaggtattat ttttgacaaa agaataaatg gccatgtctt
    16441 gaaaataaag tctgtctccg atttggactg gattttcaaa actataatca ccaatcacat
    16501 cgccagtcag acaggtatta gaagaaagtc tgtaggtatg ggctttttcc tgtgactcaa
    16561 agccatttct caaaggtgga cgatagggca tctcaagtac atcaggcata tggcaggtcg
    16621 cagaggcgtc taaaaccaag atttccatac cgttttctac aatatctaat acctcagttg
    16681 ctaaataacc cgcattaagc gcaatggctt caccaggctc gatatagatt tcaagattgt
    16741 aagtttttcg gatacgcttg atttctgaaa tcagcaaatc cacatcgtaa ccttctcttg
    16801 taatatgatg accaccaccc atattgagcc attttacctc atgtaagtag ggaccaaact
    16861 gttcttctac tgctttcaaa gttgtttgta aatcatctgc tccctgctcg caaagggtat
    16921 gaaaatgaag tccgtcaacc aaatctagca aatcgctcgg aatcttgtct atagtaactc
    16981 caaagcgaga accaggtgca caagggtcat agagcgcgtg atctccttga gttgaacact
    17041 gagggttgag gcgcaaacca acactgacac cagcctctcg acaacgagcc ccatgcttac
    17101 gcaactgtct ctctgagtta aagacgatat ggtctgttat cccaagcaat tcctccatgt
    17161 cctcatcctt gaaagctggt gcaaaaacat ggacttcacc aggaaattct tcccttgcca
    17221 atttggcctc atagagtcca ctagctgtcg tacctgatag atactggcta atcaagggat
    17281 aagttttgta gagggaatat gccttctggg caagcaagac cttgcaaccg gcctcttctt
    17341 gtacatattg tagaatgcgg caattagctt ctaacttggc caagtcaata acataggctg
    17401 gtgttggtac ttgttctaac ttcattagtc caacatttgt ggattttcaa ccacaaccca
    17461 tggcaaacca tactcattca aagcttccat gaatggatct ggatctaact cctcaaggtt
    17521 atacactcca gcttgtttcc aagttccgtt catgactaat tttgtcccaa tcatggctgg
    17581 aacgcctgtc gtgtatgaaa ttgcttgtga cccgacttct gcatagcact cttgatggtc
    17641 gcaaacattg tagatgtaga tagtcttttc aacgccatct ttgacacctg taaagataca
    17701 tccaatattg gttttaccta cagtacgtgg accaaggcta gcaggatctg gaagcaaggc
    17761 tttcaaaaat tgaattggaa caatttcttg gccgttaaag ttaatggtat ccgtacgaag
    17821 gagtccaaca ttttcaagac atttcatgtg cgtcaagtaa gattgaccaa aagtcataaa
    17881 gaaacgaatg cgtttgacac ctggaatgtt cttggccaat gattcgattt cttcatggtg
    17941 aaggagatac atatcttttt gtccaacttg agggaaatca tactcacgct tgatagacat
    18001 agcttcgact tcgacccatt tcccatcttc ccagtaagaa cctggcgcag aaacctcacg
    18061 gagattaatt tctggattaa agttggttgc aaatggataa ccgtggtcac cgccattaca
    18121 gtctaaaatg tcgatataat ggatttcatc aaaatagtgt ttgagggcat aagctgaaaa
    18181 gacactagtt acacctgggt caaaaccaga accaagaaga gcagtcaagc ctgcttcttt
    18241 gaatttctct tgataagccc actgccatga gtagtcaaag taggctgtaa aaccaagttc
    18301 cttacaacgt ttttcgtaga tagcacgcca ctcagggtct tctgtgtctt ctgcttcgta
    18361 gttggctgta tcgatatagt gaacacctgt tgccaaacaa gcatccataa tggttaaatc
    18421 ttgataaggc agagctacat tcaaaacagc ttctggtttg tagctttcaa tcagagcaat
    18481 cacttcttca accttgtcag catcaagagc agctgtctca atctttgtac ttgttttgcc
    18541 ttccagttta gctttcaagt catcgcattt tgacttggta cggctagcaa tcataatctc
    18601 tgtaaatgtt tcgctatctt gacaaatctt tgaaatagca acttgggcaa cgcccccaca
    18661 accaataact agtaaacgac tcattttttt ccttcctctt cttctaaaat gtcctcaaca
    18721 tacttgggca acataaaggc tcccacgtgt aagtttgcag tgtagtattc tgtgaaaagc
    18781 tggcgttttt tccagccttc cttgtcaaaa tctttgacag ggtggtattt tttcgatgca
    18841 aatccaaaca accaatagcc agctgggcta gttggaatat gggcctgata aacccgactg
    18901 attggaaagg cttgattgac cttgcggtgc atgcttcggc aggccgactc atcctcgtca
    18961 aagaacggac tcccatgctg gtaaatcatg atgccgtctt ccttcagagc tcgataacta
    19021 ttgccgtaga attccttggt aaagagtcct tccgtatggc caaatggatc tgtcgcatcg
    19081 ttgatgataa tatcatagtc atattcgcag tttcgcaaaa agcgtagccc attttggtag
    19141 taaatggtaa cacgaggatc atctaggcct gcagcaaagt ctgggaaata ctcacgacag
    19201 acctcgacca acatctcatc cggttccacg atatcgattt gttccagttc aggatagagt
    19261 gttaatactt gggcaacacc gccgtcacca cccccaataa ccaatacttt ctttggattt
    19321 gggtggacag ccatgggaac gtgaacggtc atttcattgt agacgaaatc atccgcatct
    19381 gagaacaaga catggccatt taaaatcagt attttcccaa aagctggcgt atccaagact
    19441 tcgatatcct gccattcact ttttccagcg taaagttgct tggctgttct cagagacaat
    19501 ttgacatctg gagtatgaac ttcagaaaac cataaatcca tctatttctc cttatattat
    19561 atttagcgca gttagctact gccaaagccc aagtggtata cttggaataa gccactgtgg
    19621 attagttcat ttcctccaat cgcttgacga tttccgaaag ggtctaacca cagctttttg
    19681 tttcaattgg taatgagttt gataacgcat agacgtttta tctcgtctaa ggtaacaagg
    19741 caaaaagttc gtggataacc aagtagactt gaaatactat atctggaggt actcccatgc
    19801 tttatgtggg cattgatgtc gctaaaaata aacacgatgt tacagccttg aatgttcgag
    19861 gaaaactgtt cttaaaccac tcactttttc aaataataaa gctggttttg aactcttaga
    19921 tctgtctctt cgacaactca accaagactg tctcatcgct cttgaaaata ccggacatta
    19981 tgcctttaat ctactgaact tcctgcatga acaaggatat aaagtttaca cctacactcc
    20041 tttgctcatc aaggaatttg ccaaatcatt atcacttcgc aa
//
LOCUS       DAVBED010000043        19045 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBED010000043 DAVBED010000000
VERSION     DAVBED010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.043"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            1..283
                     /locus_tag="VQ547_001509"
                     /pseudo
     CDS             1..283
                     /locus_tag="VQ547_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            201..629
                     /locus_tag="VQ547_001510"
     CDS             201..629
                     /locus_tag="VQ547_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2543345.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1121..1531)
                     /locus_tag="VQ547_001511"
     CDS             complement(1121..1531)
                     /locus_tag="VQ547_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543346.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1549..1926)
                     /locus_tag="VQ547_001512"
     CDS             complement(1549..1926)
                     /locus_tag="VQ547_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543347.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1868..2296)
                     /locus_tag="VQ547_001513"
     CDS             complement(1868..2296)
                     /locus_tag="VQ547_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2543348.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2340..2945)
                     /locus_tag="VQ547_001514"
     CDS             complement(2340..2945)
                     /locus_tag="VQ547_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543349.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(3035..3208)
                     /locus_tag="VQ547_001515"
     CDS             complement(3035..3208)
                     /locus_tag="VQ547_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543350.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3807..4703)
                     /locus_tag="VQ547_001516"
     CDS             complement(3807..4703)
                     /locus_tag="VQ547_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2543351.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4715..5524)
                     /locus_tag="VQ547_001517"
     CDS             complement(4715..5524)
                     /locus_tag="VQ547_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2543352.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5599..5814)
                     /locus_tag="VQ547_001518"
     CDS             complement(5599..5814)
                     /locus_tag="VQ547_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543353.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5816..6016)
                     /locus_tag="VQ547_001519"
     CDS             complement(5816..6016)
                     /locus_tag="VQ547_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543354.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(6013..6204)
                     /locus_tag="VQ547_001520"
                     /pseudo
     CDS             complement(6013..6204)
                     /locus_tag="VQ547_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6193..6483)
                     /locus_tag="VQ547_001521"
                     /pseudo
     CDS             complement(6193..6483)
                     /locus_tag="VQ547_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6653..6805)
                     /locus_tag="VQ547_001522"
     CDS             complement(6653..6805)
                     /locus_tag="VQ547_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543355.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6816..7082)
                     /locus_tag="VQ547_001523"
     CDS             complement(6816..7082)
                     /locus_tag="VQ547_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543356.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7293..7475)
                     /locus_tag="VQ547_001524"
     CDS             complement(7293..7475)
                     /locus_tag="VQ547_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2543357.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7537..8040
                     /locus_tag="VQ547_001525"
     CDS             7537..8040
                     /locus_tag="VQ547_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543358.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8114..9277
                     /locus_tag="VQ547_001526"
     CDS             8114..9277
                     /locus_tag="VQ547_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2543359.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQ547_001527"
     CDS             complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQ547_001527"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2543360.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10899..11345
                     /locus_tag="VQ547_001528"
     CDS             10899..11345
                     /locus_tag="VQ547_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2543361.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11342..12457)
                     /locus_tag="VQ547_001529"
     CDS             complement(11342..12457)
                     /locus_tag="VQ547_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2543362.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12466..12795)
                     /locus_tag="VQ547_001530"
     CDS             complement(12466..12795)
                     /locus_tag="VQ547_001530"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2543363.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12749..13111)
                     /locus_tag="VQ547_001531"
     CDS             complement(12749..13111)
                     /locus_tag="VQ547_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2543364.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQ547_001532"
     CDS             complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQ547_001532"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2543365.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQ547_001533"
     CDS             complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQ547_001533"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2543366.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15729..16871)
                     /locus_tag="VQ547_001534"
     CDS             complement(15729..16871)
                     /locus_tag="VQ547_001534"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2543367.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQ547_001535"
     CDS             complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQ547_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2543368.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5655 a         3987 c         3208 g         6195 t
ORIGIN      
        1 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
       61 accatcggtt attattatgg ataatgtaag attccataga atggggaagc tagaactctt
      121 gtgtgaatag tttgggcata aacttttacc tcttcctccc tactcacctg agtacaatcc
      181 tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa
      241 taccttttac gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa
      301 gcgaaacagc cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa
      361 aaacagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa
      421 aaccaattcc caaacatctg tcccctcaca tcttcataca catcactatt agcatcttat
      481 cagaaaataa aattccttta aaaacaatca cggacagggt tggtcatccc gactctgaag
      541 tcactaattc catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac
      601 tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgc cctctaaata
      661 caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga
      721 acttttgaat ttcatggttc gggataaaat agttcactga actattttat tttttaaggt
      781 tatcataata tcaaatagtt caattaaata cgctaaatta ctaatatact ttttaccttt
      841 ttcattctaa aatgtaaagt acaaacaatt acaatatact agagggggag taaaaaaggt
      901 aataaaattg acgagttcag caggcaaggg aaatagcact tttcatggtg ttattttttt
      961 aattcagcaa tggagtagcc gcttaattga tagaaacaaa aagcacctag tttcctagat
     1021 gctagcacaa tagcccggat tcgaaccgga atctcctcaa ttaaggtgca atccctatat
     1081 actactcatt gtgctttggt tcattatatc atacaatcaa ctagctatct accaactcat
     1141 gatacgctcc catattcggt aatggaataa tactaaaata caaatctgag taagtttcaa
     1201 accatttatt cagcttgtta taggctggcg actgactaac aaataatatc cgttgacaag
     1261 ctccgataac attcatgtga ttatacacat agacctcttt aatggccgtt aaaatatcgt
     1321 cttcacttgt ctgtacccta atatctgtta tctgcttaat cgtagcgtat tttttataag
     1381 ctagcatatc tttattttta gcagcatcaa acattttaca ctcaagaaca ctatacttag
     1441 gtttttcttt atctctcatg aaataccact tgagccataa aattttttct ctgtgaatta
     1501 ctgaaatacg ttcgattttt ttctttggca tgattacctc ctaaattatt aatctaatag
     1561 ctttaaccac tcactttttg agattgttgt ataaggttca tctagcgcgt gatataaagg
     1621 ttctaaacct ttgttaaatc ggatatagtc cattttatcc tcatgctttg gaaaatataa
     1681 gattcctgtt tcatattcat ttagaccacg gttacaccaa tcatcaacga taacctgcac
     1741 ttcccattca cgccactttt taaggttttc taaaagttca atatcactaa ataactcacc
     1801 atcaacttgg aaaaattctc ccagatcatc gttaccctcg acgatgataa cttcaggcgt
     1861 atttctacta cttaataatt ccttgagttc ttgtaactct ttgatctcct ttagatactt
     1921 cctcaatttc taacctcaat tcttcaattt gtcttactac tccaaaaatt tcatgagttt
     1981 tatatgattg ttcaagtata gtttttgctg cttgagttct tataaaaggg ttaattttgg
     2041 catccatcat aatatcattg agtacagaaa cagcattgga tgaggctaga tatagcatct
     2101 gtgtagtttt atccatcatc tcatcttgtt ttagtctcaa tgtcttttta acagctgcaa
     2161 cttttagata cttatgccct gttgcccttg acacccctgc tttttggcac gctttatcta
     2221 tcgttggctc agtaagcatg gcatctatga attttatttg tttagatgta aggccatcat
     2281 tttcatttcc tgccatctat tacctcctcg ttatcaaaat aaaggggttg ctagcccctc
     2341 tatttgttta aatactcatc caaacgacgg tcaagctcag gggcatctga atttactacc
     2401 atttcagttg ttacagcttg gattttatcg ccgttgataa gcaaactgta atgacaatat
     2461 gaaagttgcc gcttaaagaa taagattaga ctttctagcg cctgctctgc attgaataat
     2521 tccaagttga tagcaatttc tggatattgt tcagcaattg accaaagttt tttaatagca
     2581 agaggtttgt tcttgtattt ttcaaaataa cctagcaatt catcctttgt catcttcata
     2641 ctagctaaca aggtcagctc tgccacgtca tcagctgtta cgctgagttc tttttctttt
     2701 aatgcctcta gctctagatc atgctgtttt tcaatttctg catgaatttt attataggtg
     2761 tccctagaat aagtgtcccc ctctaactta taagcctcta gctggtcttt agcgtatttt
     2821 tcgcctatca taccattttg taactgttta tgtaattcct cttgtttagc aatgtagcca
     2881 gtcatgtacc catgcttttt cttgccaaaa gccttaatat catccttgat tgttgtaaat
     2941 gtcatgttat cctccttacg aaaaaataaa agaggtatga caaaagagcg ttaaactcaa
     3001 ttatcatacc tctggttttt ccagtcagta tttattaaca ttgttctcca gtggtcactt
     3061 ccttataaac taactgccca tcttgagctt ttagcttaat gctaccatga tctggaattt
     3121 caatgtactt tattatacca ttttttgagt ataaaacaaa gcctttctcc atcatttcta
     3181 ataatttatt atccttgttt tcagtcatga atttctcctt tatttcaagt gtcccaacgg
     3241 gtacggttgt aagctgagac attttagggc tatctttgag cgacaaaaat gtcgaaaagt
     3301 cttcagttcc tgtataaccg ttattagttt tgtttgctac tcatttttga gtcacaaatc
     3361 tgttaagcaa aaatgagtaa tagctcgtaa gataagtaaa tctaatactt gtattcctaa
     3421 agcgttgata taactgatat tttcaactat ccaacgctct ttactaccct ttttagtgtg
     3481 ctttagctca tttttgagct tttttgagct tttttgagtt ccattttggg aatgcaaagc
     3541 aggcgcgcac cgtgcatgct tttttcttgc tcatagcctc accctcagaa gtttgccgac
     3601 cgagagcgtg gggcttttta tttttgtata attaaaaaca gctgcacaat ttttgtacag
     3661 ctacgaccga ggcaggggcg acctgccgta ctttacacta gataatatca tctaggtagt
     3721 ccaactgtat tttatcatat taaaggctac attacaattt ctcaccctgt gaagagtgtc
     3781 tatttttgtt taggtttgta agtcgattac ttcaactgct ttaccttatt ttttaactga
     3841 ttaattgagt atcgcttatc tttgattgtg aaagccttaa aagtgttacc ctcaagacct
     3901 tttagaatac ggctataatt ccgctcgttg tatactatct tgagttcatc gctatcaaga
     3961 tttgtattaa atatagtatt ttctcgatta ttcagtacat caaaaagtaa atcctgctcc
     4021 caatcgctct taggtttaat aacagcattt tttgcaccta aatcatcaat aattaagtaa
     4081 tcaacagact tcatgagttc agtagcttca aactctgtaa gtgttgcacc tttaccataa
     4141 ttccacccct ctttaatttg tttgatcatt tcggttaggc ttacaaaaag cacactctta
     4201 ggttctcctt ttgtcttata cccctcattt atacctttgg caatagcaac tgataaaagt
     4261 gtttttccaa tccctgtacc tcctgtgata agcgtatttc ccctcatgcc atcaagatat
     4321 ttttgtacct gaccttttgc aaattctaaa aatcgctttt cttctgatgt tacagcatta
     4381 aaatcatcaa aagttttagt tttaaactca tctgctacat agctcttatt gctcatcaac
     4441 acattataag tttgcagata tagtttagca ttcaaattat cagcaatcgc atcttcttca
     4501 tcttgctttt tctgttcttc ttggcattgt tcacaatagg gtgggataca gcgaacttct
     4561 tttattacct ctccgttctc attccacccc actactacat gtctttctcc tttgatttgt
     4621 gttagctgta tttcatgctt aggacacaat tcgtctagtt taaatgtctc aatatttcct
     4681 aaactagatt gtaatgattt cattttctga cctcctaaaa tggtttttct tgtgttggta
     4741 tccaatcttc atagctggta ggctctagtt gattggtttg ctgtttttta gcctcacgcg
     4801 ctgccctgct atttctaaca agttccaccg tcaataaatt gtcctgtttc caacggttaa
     4861 ggattgcctt gatgtatgca aagtttgctt taccctgact gacagcctct tttaacgcct
     4921 catggataag ctctgggcta aaatcttcta gcatatactg caattcttga atctgtaacg
     4981 gtgacaatgc tttacctgtc tcagcttcaa aagatttata gagatttaca aaatcttgat
     5041 tgatggtaga gggagtgggt gattgttctt tatctacttc tatctctaat tctttctcta
     5101 tctctgttgg acatgagttg gaaaatgtca aagatggttg gacttcttcc aattttcctt
     5161 tttttcgttg ttcacgttta taactcgccc agtttgtttc actcataacc atagcttttg
     5221 cctgtggtag ttctgcgttt ttatcttcgt caatctgtat taaaccgcat tttgtaaagt
     5281 atgccatggt catatctata tcatcttctg atacatctaa ttttagggct aactcttcct
     5341 tgagattgtt aaagtagccc tcatagtata aaatacagtc actttccaag ctctctaaca
     5401 tgagcctaat ataaataact gtcatagtgt acccaccagg taccgtcttt agtctcttga
     5461 taaaaatatt atcaaaaaat ttcttatcaa tttttagcca aaaatagact tttgtttttg
     5521 ccatcgtcct ctcccttgct catttataat tctctacctt gattagtctt aatactcgct
     5581 tgtcattcat tgttagactc attcaattct tccccatacg tctacccctg caagctggat
     5641 atatcgccca taatcagggt ttaaatcctc gctaggtgtt tctatcgtct gttggttttc
     5701 tcgctccagt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat
     5761 caaaatcacg gtaacaaaaa ccgcctgtgt attgcttata tctagttcat tcatgttatg
     5821 ccctcgcttt gtaattcttg atgtatgcca cttgttcagc tcgcttcata ttcaacaagt
     5881 cgtctatttc cacactggtt acttttttat ttacaaaatc agaaatcagt tgaaaaatgt
     5941 ttggactttg tagctggatt tcagccattg cctcatcaaa ttctgcttgt gtcatgttgt
     6001 ctaaatctag tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttgc
     6061 tttctgagtt ccatttttag agttaaaaag aatatatttt aaggttacag tagcctctaa
     6121 atactccttt tcagcatgct ctatatacgc ctgttgctct gcttcgttct caaaaaagtg
     6181 cttagcttag cgtttaaaga atgctttgac taggtttagt ttgaattgcc gtactgcttc
     6241 ggtattcttt agataagtga tcagcaaagt agcctgttgc tcgttcagaa tataggattt
     6301 tttaggttgt cctctagtgt ctaatttatg gattttaaat ccaagtattc ccaactcttc
     6361 aaagtcaacc ttattttctc ttattaagcg tgtgatagtg tggtgttgta cgtcagcaca
     6421 ttcagcgatg atctcgcttg tggtatacgg ctctttcttg ccgtccatgt agactagttc
     6481 cattatggtt ctacctcctg tataaattta gctagcttac tttttaattg tctcctctag
     6541 ccctttttag cctctacaac ggttttggct aacgtgttag aggcttttat aacggcctgt
     6601 atagctgtct ctatttcctc cgtggaatag tagctttgtt ttctaatatc atttaagact
     6661 tgtttaaccc atttcttgaa ataaataaaa ttacatcttc tgtactcttg gcatctgctt
     6721 tatctgagac aaatagaatg tcaatgcctg gtagataaaa cccaccgtct atttgtttag
     6781 ttggtttgaa agtaactatt ttcatttcat aactcctatt ttattgctaa aaataaatac
     6841 acatctgaca gacgatagaa tactttctta gctccatcca tcggggtctg atatcgttta
     6901 agagcaagat cctcccagtt atcaagggtt gtagcactta tacctagcag atccattaat
     6961 tctttacgag aaattaaatc taacttacta gatcgttgtt tttctagctc aactaaagtt
     7021 tcaagagtct gtttaagaag ctgtaaaccc tgtaactgta tttctttaga cagaatttcc
     7081 atttatatcc tccattttcc tttttataaa ttaagttgtc tttttcctct aattttgata
     7141 aaataagaag agattattta gcaaaggggg ttgtcccttt gctaaatacc taacaaaacc
     7201 acgcgccttg cctttgcttg agttttgtta tttttcctta gccgtgtacg ttggtttggt
     7261 cgcctgtaca tggcttttta cttgcgttaa atttattcta ctagccaagt catcacgctc
     7321 tcatagatac gcttagaggc atcatagttt ccattctcaa cttttgttag tgtttgagat
     7381 ttaataccca actgctccga tactgctttt ttggttagct gtaatcttgc acgcttgata
     7441 cgtacttttt cagcaagtga tagtgtaatc aacattggtt tcacctccct tttttctcca
     7501 tttttggcat tttgtgttat aatctcttta gaaaggatgt ataagatgaa tagaattaag
     7561 caattacgaa aagaaaataa tcttactcaa agagaacttg ctaatgagac taaaatccct
     7621 tatagaacca tacaacgttg ggagaatggg gaaactgata taaaatccga tgctgctcag
     7681 gtacttgctg actattttgg agtatcaatt cctcacttac taggttatag cgatttgata
     7741 gcagatacag atagtgatat taaagcaatg gcatactcac atctactaac ttttgtagat
     7801 gaaaaacaaa tcaaagaatt tgaaaaagag ttcattcgtg caaacgataa tagtgatact
     7861 tttggtgatt taggaagtgg tgaaaaggcg ttagaaaaat actatcaagc attatgctat
     7921 ttagttcctc cttttaggga tatattggct aggtatagct ttttgtcact agatgaaaaa
     7981 aaatcagtct ataatattat tgttggttta agtaacaact tatcaaaaga aaataaataa
     8041 ctttaaacat catgtataaa tacctaacaa aaccacgcgc cttgcctgct gatggaaaga
     8101 aaggtacaaa tacatgaata tcatagagaa aattaaaaag aatggccaaa gagtttatta
     8161 tgctagtgtt tatctaggcg ttgaccaact aacgggcaaa aaagcccgta caactgttac
     8221 agcaaccact aaaaagggcg ttaaagtaaa agcgcgtgat gcgatcaata cttttgctgc
     8281 taatggctat acagttaaag ataagccgac aattacaaca tacaatgagc ttgtaaaagt
     8341 ttggtgggat agttacaaga atacagttaa gccaaatact cgccaatcca tggatggatt
     8401 ggttagagtg catttattgc ctgtatttgg cgattacaag ctatctaaac ttactacgcc
     8461 tattcttcaa cagcaagtaa acaaatgggc tgacaaggca aataaaggcg aaaaaggggc
     8521 atttgctaac tactccttgc tccataacat gaataagcgt attttgaaat atggcgtagc
     8581 tatccaggta atacaataca acccagctaa tgatgtcatc gttccacgca aacagcagaa
     8641 agaaaaggct gctgtcaaat acttagacaa caaagaatta aaacagtttc ttgattattt
     8701 agacactctg aatcaatcaa attatgagaa cttatttgat gttgtcctgt ataagacttt
     8761 attggccact ggttgccgta ttagtgaggc tctagctctt gaatggtctg atattgacct
     8821 agaaagcggt gttatcagca tcaataagac actaaaccgc tatcaggaaa taaattcacc
     8881 taaatcaagc gctggttatc gtgatatacc aatagacaaa gccacattac ttttactgaa
     8941 acaatacaaa aaccgtcaac aaattcagtc ttggaaatta ggccgatctg aaacagttgt
     9001 attctctgta tttacggaga aatatgctta tgcttgtaac ttacgcaaac gcctaaataa
     9061 gcattttgat gctgctggag taactaacgt atcatttcat ggtttccgcc atacacatac
     9121 tactatgatg ctctatgctc aggctagccc gaaagatgtt cagtatagat taggccactc
     9181 taatttaatg atcactgaaa atacttactg gcatactaac caagagaatg caaaaaaagc
     9241 cgtctcaaat tatgaaacag ctatcagcaa tttataaaaa ataagggtga cccatttccg
     9301 ggctaccctc ttactatacc aaaaattagt aggggtagta aaaagggtat taaattataa
     9361 aaagcactaa gggaaagcgc cccaaagtgc ttatttcaaa ggctttatag cctataatca
     9421 cataaggaga ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     9481 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
     9541 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     9601 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     9661 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     9721 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     9781 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     9841 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     9901 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     9961 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
    10021 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    10081 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    10141 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    10201 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    10261 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    10321 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    10381 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    10441 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    10501 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    10561 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    10621 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    10681 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    10741 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    10801 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    10861 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    10921 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    10981 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    11041 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    11101 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    11161 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    11221 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    11281 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    11341 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    11401 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    11461 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    11521 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    11581 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    11641 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaaag
    11701 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    11761 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    11821 gtcgaccttt ttgattgcca aaagtataag tcgcaccttg atgaccacat aagggactta
    11881 cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    11941 aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat
    12001 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    12061 caccaacatc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    12121 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    12181 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    12241 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
    12301 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
    12361 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
    12421 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
    12481 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
    12541 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
    12601 attgccccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
    12661 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
    12721 taaaagacct tctttgactt caagctggtt agcagtgaaa taggcaatac caagggattt
    12781 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggataccat
    12841 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
    12901 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
    12961 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tctgcctcat
    13021 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
    13081 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
    13141 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
    13201 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
    13261 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
    13321 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
    13381 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
    13441 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
    13501 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
    13561 tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
    13621 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
    13681 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
    13741 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
    13801 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
    13861 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
    13921 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
    13981 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
    14041 gcgtaacgtt caaagccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
    14101 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
    14161 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga
    14221 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
    14281 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
    14341 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
    14401 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
    14461 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
    14521 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
    14581 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
    14641 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
    14701 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
    14761 ggctatcttt aaccaagcta tccttatgga catggatatt acgtgataga acagaattag
    14821 ctacttgacc ttcaataata ctaccagagg caaactgaga agttcttacc ttagatgtat
    14881 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
    14941 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
    15001 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
    15061 ccaaatcccg taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca
    15121 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
    15181 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
    15241 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
    15301 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
    15361 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
    15421 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
    15481 agtaatggct aagaaaggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
    15541 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
    15601 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
    15661 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
    15721 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
    15781 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
    15841 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
    15901 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
    15961 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
    16021 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
    16081 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
    16141 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
    16201 ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
    16261 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
    16321 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
    16381 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
    16441 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
    16501 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
    16561 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
    16621 acacctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
    16681 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
    16741 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
    16801 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
    16861 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
    16921 gcgacgtttg attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg
    16981 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
    17041 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
    17101 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ctaacatttc
    17161 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
    17221 gacttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
    17281 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
    17341 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
    17401 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
    17461 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
    17521 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
    17581 caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt
    17641 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
    17701 aatcttggtt gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt
    17761 aataacttca ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc
    17821 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
    17881 cacacgaata ccatccaaat gatagatatc aatccaatgc ttaatgcaag aaattaagaa
    17941 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
    18001 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
    18061 attgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
    18121 ctcctcgaca aaatcttgaa actcctctgg tctaccatag gcatgctcta aagcgaagta
    18181 acccataagc tggtaccccc aactcaaacc tagtgggtgg gacatcaagg gcataaactc
    18241 aatatgagta tagttcatct caactaggta aggaatgagt tcatctttca attgggcaaa
    18301 actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct cgtaaatatt
    18361 gacaggacgt tcagcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccctcca
    18421 tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct catacctgac
    18481 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    18541 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt catttcttac
    18601 cattggaatc tgattttcaa tccaattggt aaaatcacca accaagtgaa cagcctgagc
    18661 attaggtgcc caaacacgga aggtatagcc atactctcca tttagttctt ccctatgtgc
    18721 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    18781 attatccata tactcccttt ctcctgtaag cgttttctat gtttttatta tactaccttt
    18841 ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag
    18901 ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacacctttc
    18961 tttttctact atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    19021 atttctaaca atgtcttaga aatca
//
LOCUS       DAVBED010000044        18873 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBED010000044 DAVBED010000000
VERSION     DAVBED010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.044"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ547_001536"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ547_001536"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2543369.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="VQ547_001537"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="VQ547_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2543370.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="VQ547_001538"
     CDS             2279..2812
                     /locus_tag="VQ547_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2543371.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3252..4008)
                     /locus_tag="VQ547_001539"
                     /pseudo
     CDS             complement(3252..4008)
                     /locus_tag="VQ547_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ547_001540"
     CDS             complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ547_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2543372.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ547_001541"
     CDS             complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ547_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2543373.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(6338..6733)
                     /locus_tag="VQ547_001542"
     CDS             complement(6338..6733)
                     /locus_tag="VQ547_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2543374.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(6811..7572)
                     /locus_tag="VQ547_001543"
     CDS             complement(6811..7572)
                     /locus_tag="VQ547_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2543375.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(7605..8231)
                     /locus_tag="VQ547_001544"
     CDS             complement(7605..8231)
                     /locus_tag="VQ547_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2543376.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(8247..8564)
                     /locus_tag="VQ547_001545"
     CDS             complement(8247..8564)
                     /locus_tag="VQ547_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2543377.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(8561..8860)
                     /locus_tag="VQ547_001546"
     CDS             complement(8561..8860)
                     /locus_tag="VQ547_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2543378.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9145..9336)
                     /locus_tag="VQ547_001547"
     CDS             complement(9145..9336)
                     /locus_tag="VQ547_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2543379.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(9497..10171)
                     /locus_tag="VQ547_001548"
     CDS             complement(9497..10171)
                     /locus_tag="VQ547_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543380.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(10177..10623)
                     /locus_tag="VQ547_001549"
     CDS             complement(10177..10623)
                     /locus_tag="VQ547_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543381.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(10725..11240)
                     /locus_tag="VQ547_001550"
     CDS             complement(10725..11240)
                     /locus_tag="VQ547_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2543382.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(11237..11599)
                     /locus_tag="VQ547_001551"
     CDS             complement(11237..11599)
                     /locus_tag="VQ547_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2543383.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(11665..13524)
                     /locus_tag="VQ547_001552"
                     /pseudo
     CDS             complement(11665..13524)
                     /locus_tag="VQ547_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(13541..14011)
                     /locus_tag="VQ547_001553"
     CDS             complement(13541..14011)
                     /locus_tag="VQ547_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2543384.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(14135..14851)
                     /locus_tag="VQ547_001554"
     CDS             complement(14135..14851)
                     /locus_tag="VQ547_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2543385.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ547_001555"
     CDS             complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ547_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2543386.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(17152..17484)
                     /locus_tag="VQ547_001556"
     CDS             complement(17152..17484)
                     /locus_tag="VQ547_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543387.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(17555..18163)
                     /locus_tag="VQ547_001557"
     CDS             complement(17555..18163)
                     /locus_tag="VQ547_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543388.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18176..18634)
                     /locus_tag="VQ547_001558"
     CDS             complement(18176..18634)
                     /locus_tag="VQ547_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2543389.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            18759..>18873
                     /locus_tag="VQ547_001559"
     CDS             18759..>18873
                     /locus_tag="VQ547_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2543390.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQK"
BASE COUNT         5553 a         4186 c         3433 g         5701 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 cgaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatc
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaatgccaa tcaactttca ggagacaagg gaccttatgt actgactcag
     1801 aaattagcac aaaaaggaat ttcaaaatct actatagaag aaatcttgaa tgattttgat
     1861 ttttcggaag ttgctcaacg tgtagccaat aaactattga aaaaatatga gggaaaactt
     1921 ccagctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tttgatgcta aaattgcctt tgacgaattg gatagtcaag ttgatgaaga aacgactcag
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgcccgaaa gtatgaagga
     2101 tacaaactga agcagcgttt aactcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 ccaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 caacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggg gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gaccttgttt ttttggtagt ataaaataaa ttgtgtaaac
     2881 acaaaaagga ataaatccat tatagcagag ttacaacaca tttctataaa gaaatttatt
     2941 cctacgactc agtttggcat gcttaacttc ctaactcaaa aacaaagcat cgattaattt
     3001 atccgttctt cttttgaaac agatttgaac tgataattgc tcgttttaat ttaagaagct
     3061 cttttgagca aaacttcatt tttttaagag tccaacaatt tctgtctatc gcttttctac
     3121 tagcaaaaaa cctcccttga ggcaagtttt catttatata tctaatttcg taacagtata
     3181 gtaaaatgaa ataaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
     3241 ctattctagt ttcaatctac tataaatttg atatgagaat agtctttctc aacatcctta
     3301 tccaacaagc atgctgtggc gtccttctta acttgaacca ggtcaatatt ctgggcttgg
     3361 gctgccatag acgcagccac aataacattg acgatagata tcatactcct cacacatctc
     3421 tactgaacgt ttgtagcctt gatttttctt gaaatcgttg ggaagatagt gggtcgtgta
     3481 aattttttgc acatcgattc cgatgctatt gatggtttga gaattcttat gaggactgat
     3541 ggtcaaggct gaaccaaagt agtcaaagcc caagtccata gccacttgcg ctgttttatc
     3601 cagtcggtag tcaaaacaaa ccttgcaacg gtcgccacct tcgggctcct cctctagtcc
     3661 cctaactagt tttcggtatt aattgggttc gtagggagct tctaggtact gaaccgtatt
     3721 tcctgtccga tcattaaaat cactaacaaa tttcttgatg acatagaccc gcttatggta
     3781 ttctactttg ggatggatat tagaattggc aaaatagatg gtcacatctg catacttggt
     3841 caaatattct agtgtatagg tactacaagg ggcacagcaa acatgcacga gaatggttgg
     3901 ccgctgctca tttttctccc atgcttgtac cattttctgc atgacacggt cataattaat
     3961 cttctgattg gggggcatct tgcacagaat ttcttctaca tcgatcatgt tcttctcctt
     4021 tttctagtct tattttatca tataagttag aagagctcaa atcaatttag aagtgaatat
     4081 tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg ttttctatag
     4141 aaagcttaca tcatcccgcc catcatactt ggatccattg ctggagctgg ggctactggt
     4201 tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac agatgctgca
     4261 ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc aatcatgtta
     4321 acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt caaacgatcg
     4381 ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacggg ttcttccaaa
     4441 gcacggagaa caatattacg tcctgttgct tcatctcctg tcaattccaa ggtagcaaca
     4501 gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc ttcaacagct
     4561 gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa ctcagtttca
     4621 gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa gcgttcttgc
     4681 aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat aaccgcaaca
     4741 cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct atctttgtcc
     4801 acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa ctcaagacca
     4861 aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag catggctttg
     4921 cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc acgaatcttg
     4981 ttcaaaacaa gagttggaag agcctcgcca tccacatcat ccgcaataat caagagtgga
     5041 cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt ggaaattttc
     5101 ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc gctatcagtc
     5161 accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac ttcaagctct
     5221 gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac tttttccatt
     5281 gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc aacttgagcg
     5341 atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac tgctgcggca
     5401 actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt gacgtttttg
     5461 attccttcac ggacgattgc ttgggtcaaa acagttgcag ttgtagttcc atcacctgcg
     5521 atatcattgg tttttgaagc cacttctgat accaatttgg cacccatatt ttcaaaatgg
     5581 tcttctaatt caatttcttt ggcaatagtc acaccgtcat tggtaatcaa tggtgagcca
     5641 aatgattttt caagaacgac attgcgacct tttggtccca aggttacttt aacagtgtct
     5701 gcaaggatat cgacaccacg gaccatagct gaacgggcat ctgatgaaaa tttaatttct
     5761 tttgacatac ttactttctc cttctattct tcaatgattg ccaagatgtt agcttcgcct
     5821 acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc ttcaactaag
     5881 acacggtctc cagttttaac acttggagca accaagtcac cgttcaaggt acgaacacct
     5941 tgtccagtag ccacaacttg ggctgttttg gttttttctt gggctgaacc tgcgagaaca
     6001 aagcccccaa cggtttgttc tttttcttct atttttaaga ccacacggtc ccctaatggt
     6061 ttcaacatct gatttcctcc ataatgagat agatattatt agcgctcttt atacctgagt
     6121 gctaattcat agttctattg tatcacttag tcagaaataa tcaagaaaaa agtctgactt
     6181 tctcaagata aaaagcctga gaccaactca gactttttaa tgtttatact caatgaaaat
     6241 caaagagcaa actaggaagc tagccgcaag ctgctcaaag cattgctttg atgttgtgga
     6301 taaagctaac gtggtttgaa gagattttcg aagagtatta aaatggcaat tcttcctctt
     6361 ccaagactaa atctgccaaa tcttggcctg cattattttc acgcatggca cgttgagcac
     6421 gactttccaa gagttggaat cctgttacaa gtacttcggt cacgtagttc atttggccat
     6481 ttttctcaaa gcgacgggta cgcaattctc catcaacgga aatgagacta cctttggttg
     6541 cgtagcttgc caaagtttct gctagtctgc cccataggac catattgaca aaatcagctt
     6601 cacgttcacc gttttggtct ttgtaacgac ggttcacagc gatagttgct cgcgctaccg
     6661 acttgtcatt gttggttttg tgcaattctg gtgtagacgt taaacgccca atcatgataa
     6721 ctttattata catattttct tcctcctact tatctattcg taggaaatca aaaaaagtta
     6781 cagaaatttg taacttttcg aggaaatttc ttatttttta tgaatcatga aacctgtcgc
     6841 ctgttgattg gccataatgg tcatatctgt aatctgaaca cggcgaggct gactggtcac
     6901 atagactact gtgtctgcaa tatcctgagc ttgcaaggct tctattcctt ggtaaacgga
     6961 cgcagctcgc tctttatcac catgaaaacg aacagttgag aaatctgttt cgacaatccc
     7021 aggctgaatg gttgtcacct tgatatccgt tgcgatggta tcaattcgca gtccatccga
     7081 aaaggtctta accgcagcct tggtagctga gtaaacagcg gcaccagcat aggcgtagat
     7141 tcctgcggtt gaccccatat tgataatatg accttgattg acttttatca ttgctggcaa
     7201 gaaacagcga gtaaccgcca tcagaccttt aacattggta tccaacatgg tcaacatatc
     7261 caactcctca tagtcttgat agggagccaa gtcaagagcc agtccggcgt tgttgaccaa
     7321 gatatcaatc ctccctatcg tttctagaat atcagagcaa acagtcttca ccatgaccat
     7381 atccgtcaca tctagtggaa aagtccagac ggtttgattt ggaaagctta ctgcaaactc
     7441 cgacttgagg atttctaatc tgtctatccg tcgtcctgtt agaacgacat cctcaccctg
     7501 ctccagataa gcacgcgcaa tcgcttcacc gattcctgag gttgctcccg taatcactac
     7561 attttttgcc atcttatttc cttctatcag atgctgacaa gttcctaggc agtccagtgt
     7621 ttcgctgggt cgaacggtgt tccgacaact tggtcttctg ataattcaag caccccacgt
     7681 ttttgcggag catttggcaa atgcaattca cgaggactac acatcatccc aaaactcttt
     7741 tcaccacgaa gttcgcctgg gaaaatgaaa ttcccttttg gcatcatggc accaggaaga
     7801 gccacaatgg ttttcaaccc aacacgcgca ttaggtgctc ctgcaacgat ttgcactatc
     7861 ttgtcacttg cgactgcaac ttggcagatg ttgaggtggt cactgtctgg atgagctacc
     7921 atctcgacaa tttcaccaac aacaaactta ggttccttat cattaacaat ttcttctgta
     7981 aaaccttccg cctgtaattc ttggttcaaa cgagcgactt gctcatctga taaaaagact
     8041 tgaccgcgct ctgcaatttc aaacaagctc gaaacctcaa aaatgttcca agccactgtt
     8101 tccccatttt ctttgaggaa aacacgggct accttgcctt tgcgttccac attcagtttg
     8161 gcatctccgc tatttttcac gatgaccata aggacatcac tgacatgttc tttgttatac
     8221 gtaaaaatca ttgtttcctt tttctcctat ttcaatcctg ctaaaaaatc gttaatttgc
     8281 tccttacttt tacggtcgcg attgacaaaa cgaccgattt ccttgtcctt ttctagaaca
     8341 acaaggctag gaattccgta aacatcccag agtttggcca aatccatata ctgatctcgg
     8401 tccattcgaa taaaggtgaa ctctggattg gtctcttcaa tctctggtaa ggcaggataa
     8461 atataacgac aatcgccaca ccagtctgcc acaaaaagga agaccttctt gcccgctttt
     8521 tccactaaag atgctaattc ttctaaactt gctggctgta tcataagact tcctcctcat
     8581 agactaggtc ttcattttca tagacaaagg tataatgacg gccatcctca aaaatgacgc
     8641 caccaaccaa gctctccaga ctgctttcgt aaacttgaac ataaagggtc gcaatttccc
     8701 ccatgtcgga aaaatggtct cgcacaatct ctgtcaactc ttcctgagtc ttcatgagct
     8761 tacggtcatc tgcaactttt ttcgtagcaa gagcaaggct tccgatacct agcagagcca
     8821 agcctgccat ccacattttt ttagctttca taccattcat tttaacacaa aaaaggcttc
     8881 aggacaaatg aggaagcagc agaaaagcaa gtaaaaagcc tcttccttta aggaaaaaga
     8941 cttcttatac taagagcaaa ctaggaagct agccgcaggc tgctcaaaac acggttttga
     9001 ggttgtagat aaggcgacgt tgacgtggtt tgaagagatt ttcaaagagt attattctta
     9061 ttgccaggca cctaagttgc caacgtagta actatcaggt gtgtaggtat tgcgaagcat
     9121 cttacctgat gaagccagat aatactactt gccattgtct ttgacccaat cattcgcaat
     9181 catggaacca gaagaactta cataatacca ttctcccttg tcataaaccc aagtactgac
     9241 tttcatggtt cctgagcaat taaaggcaaa aaaactgtcc aatatcattc gttttttaaa
     9301 agcatttgac actacatcat ctacgctgta gtacatagat acatcaaacg taaaagccaa
     9361 aatatcgaaa aatatacaac ttttaaaggc agcatttcat tttttaaagt ctaacaacca
     9421 tagaactgaa atcagagcaa ggcatcaatt tcctactctt agtacgtcta ttttgatggt
     9481 tgaagtgaag atttttttat ttaacgtaga caatttccaa cttcccaaaa gccacatctc
     9541 cacggatagt caaggttttg ctggttgggg ctacaggagc gtcagcctta gctgcaccaa
     9601 aggaggtttc tactttcaaa tctacacgcc agtgttgtgg aacatagacg gttgcattcc
     9661 cgaaggccac ttcaatattt aaagttgcaa aatcacctag catctctgca ttatcatagt
     9721 agattttagc atccccaaaa gcgacttcca cttggtcatc tacgagatct tgatcttgct
     9781 tatagaaggt cccgctacca aaagcgactt ccttatccgt gacgactgtt tttttcccat
     9841 tgtaccacca ttttttttca ttccagaact tacttgaatg cgtcagataa ccaacaccaa
     9901 gtaccaccaa gatgctagcc caaataagag aatgattggt aactggtaac aagtcataag
     9961 cgtaatttgc aatgatgagc gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc
    10021 taaggatgga ctcaatggac ttataagcaa aaaaaacaat acctagtaaa ggccatattt
    10081 taccatccaa agaaggaatt ccaaaattcc cttgcagcaa gatccaagct gctaaaacca
    10141 acaaaacaat accaaatgct ttctttttca tgttttttac ctcatgtttc ttagattttc
    10201 ttttaggagg gattggtaat gccgtgagac atgaacctcc ttgtgcgtct gataaaagga
    10261 aatggtgccc gttcctgaaa aggacttgtc cactgagtaa atctgacgga tgtttgcgat
    10321 cgttgacttg gaaactcgat taaaatagcg aggcaagata gactccaact catagagctt
    10381 gaggcgaacc tcataagctt ccttctggtt atgagcgtag atcttgctcc cttctgtttc
    10441 aaagaagaga atttctgaca ggtctagata atattcacct gtccccttgt aaaaagtcaa
    10501 cctcggagcc tttgactctt gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt
    10561 gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa ttcgtaactt
    10621 catcacatct cctttctgac tctactatat caaagctaag ttaggaatac aagggcaaaa
    10681 aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact tacatgtaag
    10741 aataggaaga aaaggaatcc ccacaccaaa ccacaagcat agccaaccaa gacatccttg
    10801 ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa gatcaagcat
    10861 actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt tgccgaaaag
    10921 acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg acagatatcc
    10981 caagtttcat aaggtctcgg gtgattgatt ttcttacgaa acagggacaa ggccacaaaa
    11041 cctgatgcag gaataagcac acaaacccca acttgctgac caagtcctag ttgcaggtaa
    11101 gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa acgattgaaa
    11161 ctgcgtaata ggaataaaag aattggacga ctagttagtc tggagctgat atttcgatac
    11221 cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt tgagatgttt
    11281 tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc atcagaggat
    11341 catcaatttc ctcaatacgg acactgcaaa tcttccctgt aattgcaatt cgttcaggga
    11401 cataatatgg tgcttgtcta aaaaaatctc cgtaagtaac atccctatcc agacaagcaa
    11461 gaacatcact cacttcatac cctgtcaacc aactggtcac ttggtgaact gactctgcct
    11521 ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca aatttcatat
    11581 tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa taagaaaaag
    11641 aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa attgactatt
    11701 gtacaagtca gcgtagaagc caccttgcgc catcagttcc tcatagttgc cttgctcgat
    11761 gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg acaagcggtg
    11821 ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt ggatcaattc
    11881 ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg gtgcatcctt
    11941 aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg tcacggtgtc
    12001 atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa ttcccacagc
    12061 cttactagct tccatcattc gttcatcact aatccctatt tgattataga tgagattgtc
    12121 tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg catcatgcac
    12181 ttctgaacgc gtcatagcct tggtatccac accatcaatg tgaatacttc ccttatcaat
    12241 ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagtcccag tcggcccaac
    12301 aatggcaacc ttttgaccag catgaactgt cgcagagaag tcatagtctt gaacattgac
    12361 accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca gattgaccag
    12421 agttgattta ccagaacctg ttgacccaat aaaggccact gtttgaccag tttctgcttt
    12481 aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg tcacatcctt
    12541 aaactcgacc tgacctttga agttttcatc agtcagctgc acttgaacag ggttttggat
    12601 agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag tttggggaag
    12661 aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg cataagacat
    12721 gaaaacaatc atgtcactaa agagaggcag acgcgctatc ggagcagcgt cgttaatcac
    12781 ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca tcatgatagg
    12841 attcaaaata gccataagac ggttgacaaa caaatttaaa cgggtcaatt catcatttac
    12901 tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga cacgaatacc
    12961 tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa tcaaggactg
    13021 ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa tcactgccac
    13081 aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag cccagatagc
    13141 cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt gaacttgagt
    13201 aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa tctctgtctg
    13261 cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat aagaagccgc
    13321 cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa agggcattcc
    13381 catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac tacctagcaa
    13441 atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg aaaagcaagt
    13501 aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt tgactaattt
    13561 ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga actttctcaa
    13621 aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg cgttcaaaaa
    13681 aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca aacttagccc
    13741 gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata cgcttaacca
    13801 gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta atcaagacca
    13861 agtcttggtt tttctcgcga ttatccaaaa aatgcacaac ctgaccttgc ggcccaccca
    13921 taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtgaatt tgatgaccaa
    13981 aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata aaaatagttc
    14041 tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa tcccaagtga
    14101 ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg ttcgtataaa
    14161 tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt
    14221 cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc acttggaatt
    14281 cttcaatacc agactcacgg agggcaacga tagccttgtg aaggtcagtt ggcgctgtgt
    14341 aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc gcttcgagca
    14401 attgctcaaa gactgcgtcc gcatcttcac ctccaaatac aataacacct ttgttgtcaa
    14461 agaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca aaggctgcac
    14521 ggacattggc tgctgtacgg ttgacgttag aagtcaaagt atccacaatt agcatagagc
    14581 catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg
    14641 ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta gcacggtcga
    14701 taacgaattt caaagctgag tttgattctg gatctggatc acctttttta gctgctacat
    14761 agatttctac accaaatttt gcatatactt tagagttggc tccatcttta gccgttttct
    14821 tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca cattttaatc
    14881 tttcttatta taacacaagt ttttttgatt ttcactagag gaaatggatt ttattagcaa
    14941 atcaagctag gatagcactt tacctgctaa gatggtcttg cctttctatc tttatcaaca
    15001 gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga aagtttcagc
    15061 caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa gcgacaaaaa
    15121 caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt caagtaaata
    15181 ctttgaaatc caacagttct tataggcgct attgtattct aagaaatcaa tagaagagtt
    15241 tctaagcaaa cctctaatac tcaataaaaa tcaaagagca aactagaaag ctagccgcag
    15301 gttgctcaaa acactgtttt gaggttgcgg atagggctga catggtttga agagattttc
    15361 gaagagtata atttacgtgt tcctaagatg gagaagttag actagtacac tggcacttct
    15421 aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat aaatgggtat
    15481 tagatataaa cagcaaaata tttccgatac gtgtcattct tgaatttcca atcatctaaa
    15541 acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt tttacttttt
    15601 tacacatcct gtttgataga ctcattttaa catcacgagc atactccaat ggaaatcgct
    15661 aggcaagaga taaactttca gatattcgca gagagctcat cgcctctttt tgtcgcaaac
    15721 attcttctct cctaatcatt ttctacctta tcctctacct gaggatagag agttgttccc
    15781 caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata aaccgtacgc
    15841 caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt gcgaacattc
    15901 ccttttaaag gaatactagt ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa
    15961 gccttaggag tcaagacttc cttgccttga tgatcatagg ataattcatc ccaagtaata
    16021 taatattggg caacataggc accactatga tccagcagta aatctccgtt tctgtaagct
    16081 gtaaccttag tctcaacata gtctgtactg ttttgaaagg tcgcaactac attgtcacgt
    16141 aaaaaagaag ttgtatagga aatcggcaag cctggatgat cggctgtaaa gcgactgcct
    16201 tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc acccgaactt
    16261 gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg cttccactct
    16321 gtctgaggag ctactccttt tatcaaagat tcaaaagcag cctctacttc atcactctta
    16381 ctcgtggttt ccaacttgag atagacttgg cgcccataag caacactcga aatatagacc
    16441 aaaggacgct ctgcagaaat tcctctctgc cttaaatcct ctaccgttac agtatcttga
    16501 aacacatctc ctggattttt aacagcatct acgctgactg tataataaat ctgcttaaaa
    16561 ttaacaatct gaatctgctt ttcgcctgaa tggacagagt taaaatcaat atcaagagaa
    16621 ttccctatct tttcaaagtc agaaccaaac ttgaccttga gttgttccat gctgtgagcc
    16681 gtgatttttt catgctgcat tctagctggg acattattga cctgaccata atcttgatgc
    16741 cacttagcca acaaatcgtt taccgctccg cgaacacttg aattgctggg gtcttccact
    16801 tggagaaagc tatcgctact tgccaaacca ggcaaatcaa tactataagt catcggagca
    16861 cgatcgaccg caagaagagt gggattattc tctaacaagg tctcatccac tacgagaagt
    16921 gctccaggat agaggcgact gtcgttggta gctgttacag aaatatcact tgtatttgtc
    16981 gacaagctcc gcttctttct ttcgataaca acaaactcat cgggtagctg attaccctct
    17041 ttgatgaaac gattttcaat actttctccc tgatgggtca agagtttctt tttatcgtaa
    17101 ttcatagcta gtataaagtc atttactgct ttatttgcca tcttctacct cctaataagt
    17161 tcctggattg agttgcataa actcagactt gttcagcgaa atcagccgtg gttggactaa
    17221 gtaatccaaa atttcctcgt acaattcttc tgagacattg cgtcgccgtc tggctaaata
    17281 agaagtcgga atgaccgtat tatccaacat aaatacctta tctaagtcaa tcaaggttgg
    17341 tcttgtaaaa ggattacgag ctagatccgg ctcttctatc ataaagttct tgaccaaacg
    17401 tctggtcaag agagctggtt tgaaggtctg atttttaacc aactctttgt ttttagtcat
    17461 gctgttgtca atacagatat acatatgatt cttcacagcc aaatcgctac taatagtcgg
    17521 aaaaggcaaa taaagagcta caacatctcc tctcttaatc aagcaagagc accccctttt
    17581 ctcctaatgt aacatagaca ggattgacca agtcttctga ttgactcaga atttccaaag
    17641 tttgagtttg gcgcgctgtc aatttagtag catcttgtct cttcaataca aaatgcttgt
    17701 cgccaataac cttgacaata taatccttct ccaaagctga ctggtaaatc cacatcagat
    17761 gttgtctgtc ctgagaactc aagagagaag gattttcaag cctcccgata gtctgataaa
    17821 aatcaaaaac aggagctaac tcctgccaat ctgattggct agttgtcaag gctagaaaaa
    17881 gggctttgcg agctgatact tcttggttag ccttgagagt tactttcccc tccaagtttt
    17941 ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa ctgcgagaaa taaaaacctt
    18001 tcgttcccag acataagtct ttcatgtcgc tttctctagc aaataagagc tcaaacattt
    18061 gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat cttttcctta tcggcttctt
    18121 tttttaacca gagcaagggc gacaggtagc tggattgaga catttcctct acctcctact
    18181 cttttttaac tggagcatct gcactagctg ccacttcttt tgactggata ctttcccact
    18241 ggttaatctc ctctgagata agaccttcgc atgtcttgac aaatagggca aaagccttgg
    18301 tctttcctgc atatttctcc gtttggcatt gatagaggaa tttttctttc tccaggagtt
    18361 gcgcagtttt ttggtaagaa atccaatttt cctttgcatt atacaaattg ataatcccct
    18421 cacacagcaa gccgagactg gataaggcaa ccgaaatcaa acggtagcga tcacctggca
    18481 taggaatagc acaaaagaca gctatgagga aacctgccac gatttctgtt atttttaata
    18541 ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa atgagctatc tgtacgtcta
    18601 atcgctctgt caggtacatt tcttctggcg tcatattcgt aactcctttc atttactttg
    18661 ataaccatag tataacatat ttgaatatca aagtatagta aaaactggac tataacttat
    18721 tagactccct gcgaaacaaa atatggtata gtagttctat gaattatgaa gcaagtaaac
    18781 aattaactga tacacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
    18841 tgttagctgt attaaaaaca gcttatcaaa aaa
//
LOCUS       DAVBED010000045        17799 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBED010000045 DAVBED010000000
VERSION     DAVBED010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.045"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..155)
                     /locus_tag="VQ547_001560"
     CDS             complement(<1..155)
                     /locus_tag="VQ547_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543391.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMK"
     gene            complement(406..1341)
                     /locus_tag="VQ547_001561"
     CDS             complement(406..1341)
                     /locus_tag="VQ547_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2543392.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1338..2198)
                     /locus_tag="VQ547_001562"
     CDS             complement(1338..2198)
                     /locus_tag="VQ547_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2543393.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2306..4468
                     /locus_tag="VQ547_001563"
     CDS             2306..4468
                     /locus_tag="VQ547_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2543394.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4560..5819
                     /locus_tag="VQ547_001564"
     CDS             4560..5819
                     /locus_tag="VQ547_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2543395.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKEGMVNDLNAFFNPMKADVD"
     gene            5833..6699
                     /locus_tag="VQ547_001565"
     CDS             5833..6699
                     /locus_tag="VQ547_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2543396.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6713..7546
                     /locus_tag="VQ547_001566"
     CDS             6713..7546
                     /locus_tag="VQ547_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2543397.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            7547..7627
                     /locus_tag="VQ547_001567"
                     /pseudo
     CDS             7547..7627
                     /locus_tag="VQ547_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7765..9207
                     /gene="gtfA"
                     /locus_tag="VQ547_001568"
     CDS             7765..9207
                     /gene="gtfA"
                     /locus_tag="VQ547_001568"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2543398.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            9345..10538
                     /locus_tag="VQ547_001569"
     CDS             9345..10538
                     /locus_tag="VQ547_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2543399.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11225..13204
                     /locus_tag="VQ547_001570"
     CDS             11225..13204
                     /locus_tag="VQ547_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2543400.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13271..14767
                     /locus_tag="VQ547_001571"
     CDS             13271..14767
                     /locus_tag="VQ547_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543401.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14767..15693
                     /locus_tag="VQ547_001572"
     CDS             14767..15693
                     /locus_tag="VQ547_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543402.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15702..16769
                     /locus_tag="VQ547_001573"
     CDS             15702..16769
                     /locus_tag="VQ547_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543403.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16780..17706
                     /locus_tag="VQ547_001574"
     CDS             16780..17706
                     /locus_tag="VQ547_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543404.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5234 a         3174 c         3715 g         5676 t
ORIGIN      
        1 ttcttcatta gacttccaca atcagggcaa gatggagcct cataatccag cttagcgata
       61 atttctttgt gggtatccat attgatgata tctagaatct tgatgtttgg gtctttaatg
      121 tctagtaatt ttgtgataaa atgtaattgt tccatatgat tctttctaat gagttgtttt
      181 gtcgcttttc attataggtc atatgggact ttttttctac acaaaatagg ctccataata
      241 tccataggga atttacccac tacaaatatt atagagcccg ttttaatgag agtttgtaac
      301 tctctttttt gtttttagag acaataaaac ttcagatccg taaaacttaa ttgaattact
      361 aatctgaagt tatttttata tcgtttatat tataattgtg ttattttact tccaactatt
      421 gagagaaatt tcgccactat ttagccagat ttcttttccg ttatcacatt gaactaaaag
      481 ttttccattt tctgagatgt ctttagcaag tcccttgtag tctttttgct ctagtgtgaa
      541 agtgacttct tttcctagaa tgaatgactg ttttttgtat aggtataata gctcttctgc
      601 tggtgtttcg aagaaagcac gccagatttc tatgatcaat tcattccttg ttataggagc
      661 tgtagcttta aataagctgg cagctttttc ttttaattcc tgagggaagt ctttaatagt
      721 gaaattgata cctactccaa taatgatatc tgtgactaag ccagtttcta cagaggtcat
      781 tgcttcagta aggattcctc caattttatg attgtttaga tagatatcat tgacccattt
      841 tatgtcgaca tctattaaag ttaggttctt aatggctttg tagacagctc cagctacaag
      901 tagtgtgtag gatggtaatt tgtcataggg gagatttggt ttaagatgga gtgtcatata
      961 aataccacct tgtggtgagt agaaggaacg ttgaaaacgg cctcggcctg ctgtttgata
     1021 ggaagctaga tagagggtat ttgcttcatg gcctaaatca attgcttctt ttgcatctag
     1081 ttgtgttgat tttgtttcgg gtttaaagct gactttaatt ggaagatttt cttctagaat
     1141 ctctggaaga ataaggtcac cattcatcag tttatatcct ctatttttga tactatcaat
     1201 ttcaatgcct tcttgttcta gtcgcttgat ggctttccaa attgctgttc ggcttaggga
     1261 tagtttttct gcgatttttt ctccgctgat atagtcggtt tctttagata ggatttggta
     1321 gacagcttgg taggatttca taatgttgcc tttctcacta gttggtattg agagtattct
     1381 tttcttgtat gacttggagt ctgattaaag tattgtttat aagctttcga aaaatggagt
     1441 ggatctgaaa aacctaccga gtatgcaatt accttgatgg actcttgggt attttcgaga
     1501 agttgtctag ctcggtgcat tcgaacgtag agtaggtatt ctttgggtga taaggtatta
     1561 aattctttga atacgcttga taagtagctt ctgtgaacgg atagttcttt tgctaaatct
     1621 tgaattgtaa gtgattgagg atagtggcta tcaattaatc gtttgcattc aagatagagt
     1681 tggtgggttg atgaaatatt cttttttttc tgattgggag caatagttcc cagatgaaac
     1741 atcagttcat gaagttgtcc catgatatgg agttgagcta attcacttga ttttgtaatc
     1801 tgagcgaagc ggacaatgtc tgagatgagt tttgcagtag tctgggtatg acaagtttca
     1861 gattggatga gataggattg atcagaaatt tgagaaagag caaaataatc aggggatttc
     1921 cctccagtga ttcctaacca gtagtaggcc caaggttctt tactatctgc ttgataaaag
     1981 gttagttcct ctggttttaa tagaaagaaa tctccttctt ttaaatcaac aattttaccc
     2041 ttgtaataaa attttccttg tcctttagta atgtaatgta gaacgtatgt atcacgaatg
     2101 gctggaccaa aagagtaatt aggtgtgcat tcctcatatc cataaaagct tagggcaagg
     2161 tcgattgttc cagtctggta ttctgaaaaa actaacatgt gctacctcct acctaacatt
     2221 ttaccatatt cttgagacat ttttctattt tggaaagcga tttcaggtga taaaatataa
     2281 tcaataaagt gatgaggtga agtaaatggg agttaggata gagaataatc tattttatgt
     2341 tgagagtaaa aatctaagtt tgattattga aaatcgaaat ggctacttac ttttgaaaca
     2401 tttaggaaag actattaaga actataaagg ttccaatagt gtttatgaac gagaccatgc
     2461 cttttcagga aatccaacgg ctactaatcg aacctttagt ttagatactc agcgacagat
     2521 ttttggacaa catggcttag gagattttag gaaaccaact atacaggttc agcatagtgt
     2581 aactgaagta acagactttc gatttgtaga agcaaagatt ttaaaaggtc agaatggtcc
     2641 acagggctta ccttctccac atagcatgga cgatacagag actcttgtct taatgttaga
     2701 agattctaag gctcaactta gtctgacttt gtattatact acttttaata atgatgcgac
     2761 tattactagc tacagtaaat tagataataa tagtaatcag gaagttgtca tccataaaga
     2821 tttttctttt atggctgatt ttccagctgc agattacgaa atagcaactc tgcagggtgc
     2881 ttatgctcgt gaaaagactg ttagacgtca acaggtagaa caaggaatct tttcgattag
     2941 ttcaaaccga ggtgcttctg gtcatgctca aacaccagct cttctactat gcgaacaagg
     3001 agtcacagag gatgctggga atgtgtttgc tattcaacta atgtatagtg gcaactttga
     3061 agcttttgtt caaaaaaatc aattgaatga agttcgggtg gctattggca ttaatccaga
     3121 aaacttttct tggaagttag cccctgagga atactttgaa acaccggtag ctttagtgac
     3181 tcattcagat cagggattaa ctggtattag tcatgaaagt cagaattttg tactgaagca
     3241 cattattcta agtgaatttt ctaaaaaaga acgtccaatt ctaatcaata actgggaagc
     3301 tacttacttt gactttcaga gagaaaaact gttagagtta gcagatgaag ctaagaaagt
     3361 tggcattgaa ctttttgtat tagatgatgg ttggtttggc aatcgttttg atgataatcg
     3421 tgctttaggt gattgggttg ttaatgagga aaaactgggt ggaagtctag aaagtctgat
     3481 ttcagctatc catgaaagag gtttgcagtt tggactttgg ttagaacccg aaatgatttc
     3541 tgtagatagt gatttgtatc gtcaacaccc tgactgggct attcaggttc ctgactatga
     3601 gcatacttat tctcggaatc aattagtact taatcttgcc aatcctcagg tagtagaata
     3661 cttgaaaagt gtcttagatc aactcctatc ttatcatgag attgattaca ttaaatggga
     3721 tatgaaccgc aatatcacta agctagggaa tggattaact tatctagaga cacagatgca
     3781 atctcatcag tacatgctgg ggctttatga actcgtttct tatctgacag agaagcacag
     3841 ccatattctc tttgagtcct gctctggtgg tggtggacga aatgatcttg gtatgatacg
     3901 ctatttccca caagtctggg ctagtgataa tactgatgcc attgcacgtt taccaattca
     3961 atacggttca tcctatttct atccaaccat ttctatgggg gctcatgtgt cagcagtacc
     4021 gaatcatcag atgggacgaa tgacaccatt agaaacacgt ggccatgtag caatgatggg
     4081 aaatttgggc tatgagcttg atttgacaaa tttatcagat gaagagaaag ctacgattgc
     4141 taatcaggtg aacttgtata aagaattacg accagtagtt cagttaggac agcagtatag
     4201 actaattaat cctgatactg catccaatga agcagctgta caatttaatt acggaaatca
     4261 aacgattgta acctacgttc gcgttttatc tgttgtagag accatggaaa caactttaaa
     4321 attaaaagat ttggatgaag agggactata taaattacag gaaaatggcg aagtttactc
     4381 aggtgcagaa ctaatgtatg cgggcttaac tgttatctta tcccaaggag attttttgag
     4441 tagacagtat atttttagaa aactatgata tgtactgacc ccaaaagtta gatttattct
     4501 atctaacttt tgaagtgcag tttgataagg gtgtataaat ttataaagga ggctttctaa
     4561 tggaatggta taaaaaaatc ggacttcttg caactacagg tttagctttg tttgggctcg
     4621 gtgcttgctc caactatggt aaatctgcgg atgacacagt gaccatcgag tatttcaacc
     4681 agaaaaaaga aatgaccaaa accttggaag aaatcactcg tgattttgag aaggaaaacc
     4741 ctaagataaa ggtcaaagtc gtcaatgtac caaatgctgg tgaagtattg aagacacgcg
     4801 ttctcgcagg agatgtgcct gatgtggtca atatttaccc acagtccatc gaactgcaag
     4861 aatgggcaaa agcaggtgtc tttgaagatt tgagtaacaa agactacctg aaacgcgtga
     4921 aaaatggcta cgctgaaaaa tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag
     4981 ctaatgctta tggaatttac tacaacaaag ataaattcga agaactgggc ttgaaggttc
     5041 ctgaaacctg ggatgaattt gaacagttag tcaaagatat cgttgctaaa ggacaaacac
     5101 catttggaat tgcaggtgca gatgcttgga cactcaatgg ttacaatcaa ttagcctttg
     5161 cgacagcaac aggtggagga aaagaagcaa atcaatacct tcgttattct caaccaaatg
     5221 ctattaaatt gtcggatccg attatgaaag atgatatcaa ggtcatggac atccttcgca
     5281 ttaatggctc taagcaaaag aactgggaag gtgctggcta taccgatgtt atcggagcct
     5341 tcgcacgtgg ggatgtcctc atgacaccaa atgggtcttg ggcgatcaca gcgattaatg
     5401 aacaaaaacc gaactttaag attggaacct tcatgattcc aggaaaagaa aaaggacaaa
     5461 gcttaaccgt tggtgcggga gacttggcat ggtctatctc agccaccacc aaacatccaa
     5521 aagaagccaa tgcctttgtg gaatatatga cccgttcaga agtcatgcaa aaatactacg
     5581 atgtggacgg atctccaaca gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc
     5641 ttgctggtat gaccgaatat gcctttacgg atcgtcactt ggtctggttg caacaatact
     5701 ggaccagtga agcagacttc cataccttga ccatgaacta tgtcttgacc ggtgataaag
     5761 aaggcatggt caatgatttg aatgccttct ttaacccgat gaaagcggat gtggattagg
     5821 agtagagaga ctatgaaaaa agtattacaa aaatattggg catgggcttt tgtggtcatc
     5881 cccctcttgt tacaagcaat tttcttctat gtgccgatgt ttcaaggagc cttttacagt
     5941 tttaccaact ggacaggatt gacttacaac tacaaatttg tcggcttaaa caactttaag
     6001 ctcctcttca tggatccaaa attcatgaat gcgattggct ttaccgcaat cattacgatt
     6061 gccatggtgg ttggtgagat tgcactcggg atcttcattg cgcgtgtctt gaactctaaa
     6121 atcaaaggcc aaaccttctt ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg
     6181 acagtggctt tgatcttcaa gcaagtcttc aactacggtc ttccagcgat tgggaatgcc
     6241 cttcatattg aatttctcca aaccagtctt ttagggacta agtggggagc aatctttgcg
     6301 gctgtctttg tccttctttg gcaaggggtg gctatgccca tcatcatctt cctagctggt
     6361 ttgcaatcta ttccaactga gattacagag gcagcaagga ttgatggtgc gactagcaag
     6421 caagttttct ggaacattga attgccttac ttgctaccaa gtgtctctat agtctttatc
     6481 ctagccctaa aaggtgggct gactgccttt gaccaagtct ttgccatgac cggtggtggt
     6541 ccaaacaatg ccacaacctc acttgggctc ttggtttata actatgcctt taaaaacaac
     6601 caattcggtt atgccaatgc cattgccgta atcttgttct tcttaattgt agtgatttcg
     6661 atcatccaat tgagagtatc taagaaattt gaaatttaag aggagaagca tgatgaaaca
     6721 agatgaaaga aaagccctga ttggcaaata cattctattg attctaggat cggttctgat
     6781 tttagtgccg ctccttgcta ccctctttag ttccttcaaa tccactaagg atattgtaga
     6841 taatttcttt ggctttccaa ccaacttcac atgggacaac tttagccgtc tcttagctga
     6901 tgggattgga ggctattatt ggaactctgt cgtcatcact gtcttgtctt tacttgcagt
     6961 aatgatcttt atccctatgg cagcctactc catcgctcgc aatatgagta aaagaaaagc
     7021 ctttaccatc atgtataccc tcttaatcct cggaatcttc gtacctttcc aagtcatcat
     7081 gattccgatt acggttatga tgagtaaact cggtttggct aatacctttg gtttgatctt
     7141 gctctacttg acctatgcga ttccacagac cctctttctc tatgttggct atatcaaaat
     7201 ctcgattcca gaaagtctgg atgaagcagc agagatcgat ggggctaatc aatttacaac
     7261 ctatttccgc atcatcttcc caatgatgaa accgatgcat gcgacaacca tgatcatcaa
     7321 tgccctttgg ttctggaatg acttcatgtt gccactcctt gtcttgaacc gggattccaa
     7381 aatgtggact ctgcctttgt tccaatacaa ctacgcaggc caatatttca acgactacgg
     7441 accaagcttt gcctcttacg tggtcggcat tatcagtatc accattgtct atctcttctt
     7501 ccaacgccat atcatcgcag gaataagcaa cggggcagtg aagtaatact caatgaaaat
     7561 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
     7621 tgaaactgac gaagtcagta accatatcta cggtaaggcg acactgacgt ggtttgaaga
     7681 gattttcgaa gagtataaca tgaatttgat ttacgaagcc agatcatatg agacttggct
     7741 tcaattagaa aaaggagagt aatgatgcca attcaaaata aaaccatgtt gattacctat
     7801 tctgatagcc ttggaaataa tcttaaagac ttatatgata atttggaaga gcattttgga
     7861 gatgctattg gaggagttca ccttttacca tttttcccat caacaggtga tcgtggattt
     7921 gcgccagttg actacgacga agtggactca gcttttggtg attgggagga tgttaagcgt
     7981 ttaggtgaga aatattatct tatgtttgat tttatgatta atcatatttc tcgtcaatcc
     8041 aagtattata aggactatca agaaaaacat gaagccagtg aatttaaaga tctcttttta
     8101 aactgggata agttttggcc agaaaaccgt ccgacacagt ctgatgtaga tttaatttac
     8161 aagcgtaagg atcgtgcacc aaagcaagag attgtgtttg aagatggttc agtggaacat
     8221 ttgtggaata cctttggtga ggagcagatt gatcttgatg tgaccaaaga agtaactatg
     8281 gaatttatcc gtaagaccat tcagcacttg gcaagtaatg ggtgtgattt gattcgtcta
     8341 gatgcctttg cttatgcagt gaagaaattg gatactaatg atttctttgt ggaaccagat
     8401 atttgggatt tattggacaa agttcgagat atcgctgctg agtatgggac agagatttta
     8461 cctgagattc atgaacacta ttcgattcag tttaaaatag cagaccatga ttactatgtt
     8521 tatgatttta ctcttccaat ggtgacactt tatactcttt acagttccag aacagagcgt
     8581 ttggctaagt ggttgaagat gagcccgatg aagcaattta cgacgctaga tacccatgat
     8641 gggattggag tagtagatgt caaggatatc ctgaccgatg aggagattga ctatgcttca
     8701 aatgaactct ataaggttgg agccaatgtc aaacgtaagt actctagtgc cgagtataac
     8761 aacttagata tctaccaaat caattcaacc tactattcag cgcttggaga tgatgatgtc
     8821 aagtattttc tcgctcgtct aattcaagct tttgccccag gtattcctca ggtttactat
     8881 gtgggtctat tagcaggcaa gaatgacttg aaattattag aagaaactaa agaaggtcga
     8941 aatattaatc gtcattacta tagcaacgag gaaatagcaa gagaagtgca acgacctgtt
     9001 gtgaaggccc ttctcaatct attttctttc cgtaaccgtt cagaagcctt tgatctagaa
     9061 gggactactg agatagagac accaacagct cacagcattg taatcaaacg tcaaaataaa
     9121 gataagtccg taacagcagt agcagaaatt gatttgcaaa atcagactta tcgggtaatt
     9181 gagaatggag ttgaagtatc attttgaagc cttgatatgg tggataaaat agggttttta
     9241 ttttggaaaa cgtttccttt gttttcaaat tgctaaaaaa gtggtacaat ataggatagc
     9301 ttactattat ctgaatcagc tgatttggag agaaaggatt cattttgaaa tcaataggct
     9361 ttattgaaaa gctgaagggg ttgtctagta aagagctgat tttattggga attatcctaa
     9421 gtatcttttt acccttttat ctttttgtag ttgtactctg tttatatatt atcagtttga
     9481 tttttacagg agacatgaaa agtattcttc agaaaatggg ggagcatccg atgctgcttc
     9541 tttttcttag ctatagtact gttatatcca ttcttgcaca aaattggatg ggtcttgtgg
     9601 cttcagtagg aatgtttcta tttactattt tctttttgca ctatcagtcg attttatccc
     9661 ataaattctt tcgattgatt ttgcagttcg tcttgtttgg tagtgtcttg tcagctgctt
     9721 ttgccagttt agaacatttc caaattgtga agaaatttaa ctatgctttt ctttcaccca
     9781 atatgcaggt gtggcatcag aaccgggcag aagtgacctt ctttaatcct aattattatg
     9841 gaattatttg ttgtttctgt attatgattg ctttctatct gtttacaacg accaagttga
     9901 attggttgaa agtattctgt gtgattgcag gctttgttaa tctctttggt ttgaacttta
     9961 ctcaaaatcg aactgccttt cctgctatta tcgctggagc aattatctat ctctttacga
    10021 ctattaaaaa ctggaaggcc ttttggctta gtattggggt cttcgcgatt ggtttgagtt
    10081 tcctcttttc tagtgatttg ggagttcgaa tgggtacttt agactcttct atggaagaac
    10141 gcatttctat ctgggatgct gggatggcct tgtttaagca aaatcctttt tggggtgaag
    10201 ggccattgac ctatatgcac tcttatcctc ggatacatgc tccttatcat gaacatgccc
    10261 acagtcttta tattgatacg attctgagtt acggaattgt gggtaccatt ttattagttt
    10321 tgtcttctgt tgctcctgtt cgcttgatga tggatatgag tcaggagtcg gggaaacgtc
    10381 cgattatcgg cctttatcta tctttcctta cagtggttgc tgtgcacgga atttttgact
    10441 tggctctctt ctggattcag tcaggcttta ttttcttgct agttatgtgc agtattccat
    10501 tggagcatcg aatgttggta tcggacatga cggattaagt tttataagtt tgaaatcttc
    10561 taccttgggt aggagatttt tttatacgat gggcatgtcg tgcatctgag gtgtaagtcc
    10621 tctgtaggga tccactaccg gtgaatacaa tagcgctccc caagcctgac tatcgtgagg
    10681 tagcggatta aaatggtctg gggatagatc gttttaagtc tgacgcagga aataagaatt
    10741 gtcagagaaa gcaatagtga aatcgtaggc tatgaataga aacgtgatag cgaggagcat
    10801 atagtggata aggtagcgag aaattttaaa gtataaaaga tagtcttaat ctatatatgt
    10861 aaatcacaaa agtaattgaa ttcggaataa ggttggtgtg aaaagacata gtaaactgaa
    10921 tcttgaatac tagaatgata cttctacaat attgttataa tttaatttga attccaaaat
    10981 cacattgttc cgtccgtatt tcattttact gtatgtcttc ctaaactcca aagtttctgc
    11041 gtcaaatttc ctattttcac tgtagtcttt gacacttcga acgacaattt gaatcatata
    11101 ttcaaaaaaa aatgaaaaat ttgtgccaac aagcctaaat attctgaaaa tttgtttgat
    11161 ttttaatgga taatgtgata taatggttgt caatctataa ttcacataaa cagaggagta
    11221 gaaaatgaaa aaaaatcgtg tatttgctac agcaggtctt gttttattag cagcaggtgt
    11281 acttgcagca tgcagttctt caaaatcatc tgattcatca gcccctaaag cttatggcta
    11341 tgtttataca gcagacccag aaaccttgga ctacctgatt tcaagtaaaa atagtacaac
    11401 agtagtgact tcaaatggga ttgatggttt attcactaac gataattacg gtaatcttgc
    11461 tcctgcagtt gcagaggatt gggaagtctc taaggatggt ttgacctaca cttataagat
    11521 tcgtaaaggg gttaaatggt ttacctctga tggagaagaa tatgcagagg tgacggctaa
    11581 agatttcgtg aacggtttaa aacacgcagc agataaaaaa tcagaagcta tgtatttagc
    11641 tgaaaattcg gttaaaggct tggcagatta tctatcagga acttcaacag atttttcaac
    11701 agttggtgtc aaggcggttg atgattatac gttacaatac actttgaacc agcctgaacc
    11761 gttctggaac tctaagttga cctattctat tttctggcct ctgaatgaag aattcgaaac
    11821 atcaaaagga agcgattttg ctaaaccaac agatccgaca tccttgcttt ataatggtcc
    11881 attcttgttg aaagggttga ctgcaaaatc ttctgtagag tttgtaaaaa atgagcaata
    11941 ttgggataaa gaaaatgtcc acctagatac tatcaatcta gcttactatg atggatcaga
    12001 tcaggagtcg ctagagcgta acttcactag tggagcttat agttatgccc gtctttaccc
    12061 taccagctcc aactattcta aggttgcaga agaatacaag gacaatatct attacacaca
    12121 atcaggctct gggattgctg gtctgggtgt gaatattgat cgccaaagtt acaactatac
    12181 ttctaaaact acagattcag agaaagtagc tactaagaag gcattgctta acaaagattt
    12241 ccgtcaagcc ttgaattttg ctcttgatcg ctcagcttac tcagctcaaa tcaatggtaa
    12301 agatggagca gctttagcag ttcgtaattt atttgtaaaa ccagactttg tttcagctgg
    12361 tgagaagacc tttggtgatt tagtcgctgc tcaacttcct gcttatggtg atgagtggaa
    12421 aggtgtgaat ttagctgatg ggcaggatgg tttattcaat gctgacaagg ccaaggcaga
    12481 gtttgcgaaa gctaagaaag ctttagaagc agacggcgtt cagtttccta ttcatctgga
    12541 cgttccagta gaccaagcat caaaaaacta catatctcgt attcagtcct ttaaacaatc
    12601 tgtagaaaca gttcttggtg ttgaaaatgt cgttgttgat attcaacaaa tgacaagtga
    12661 tgaattcctt aatattactt actatgctgc caatgcttca tctgaggatt gggatgtatc
    12721 gggaggagtt tcatgggggc cagactatca agacccatct acttacctgg atattttaaa
    12781 aacaactagc agtgaaacta caaaaacata tttaggattt gataatccaa atagcccttc
    12841 agtagttcaa gttggtttga aagaatacga taaattagtt gatgaagctg ccaaagagac
    12901 aagcgacttg aatgtccgtt atgaaaaata tgcagcggct caagcatggt tgacagatag
    12961 ttcactcttt attcctgcta tggcttcttc tggtgcagca ccagtgcttt cacgaattgt
    13021 tccatttact ggagcttctg cgcaaacagg ctctaagggg tcagatgttt acttcaaata
    13081 tttgaaatta caagataaag tggtgactaa ggaagagtat gaaaaagctc gtgaaaaatg
    13141 gttgaaagaa aaagctgaat caaatgagaa agctcaaaaa gaattggcaa gtcatgtgaa
    13201 gtaaataatt tctaatagaa ctttctctcc atgaggagaa ggttcttttg ggatttttaa
    13261 aggaaataat atgaaaaaat atatttttat gcgtgttttg cggtcattgg tttcgatttt
    13321 cttagtaacg actttgacct acacgattat ctataccttg gttcctcgaa aattgatttt
    13381 caagcaggat cctaactata ataaaattgc aacaacggct gataaacgtg ataactatga
    13441 aaatactgtg tttgagcgta tgggctacat tgagtattac gatactaaag agttgcaaga
    13501 aaaggcaagt agcatggatt cttctgtaac agtagaagca aatgcgacca ataaagctat
    13561 ttatgaaaag tacatcaatc aattaggtca tggttggact ttgggagaat ttactgaaag
    13621 tggtcaattc tatgctactc gtgaaattcc aatttttgaa cgtgtttttc acttctatgc
    13681 taacttgatt gacattgacc atacaaataa aatccaagac cctgaaaatc cagacttgaa
    13741 acgctacctt cgttttgaaa atgatccagc tatcggatgg tcattggtcg gttcaggaac
    13801 taaacataaa tatctcttgt actttaacag tcagttccca tttgttcatc aaaactttgt
    13861 gaacttgaat ttaggtgact cttacccaac ctatgctaat acaccagttc ttcaggttat
    13921 tactcaaggt caaggacaaa ccaaaactgc ccaagttcag ttcccaacag gtaagaaaac
    13981 gtcttctgta aatatttact caagaaccta caagtcacct agtcaggctg actctcgtga
    14041 agtagctagc tatgggaaag atgatcctta tacagcgact gaaagtaatt accaatatcc
    14101 atctatgatt gtcagctctg ctattactgg tttgattggt ttggttcttg cctatgctct
    14161 tgccgtgcca cttggttcag ccatggctcg tttcaagaac acttggattg atagcctctc
    14221 aacaggggct ttgaccttct tgcttgctct tccaacgatt gccttggttt acatcgttcg
    14281 attgattgga tcatctattg cccttccaga ttcattccct atcttgggag ctggagattg
    14341 gcgttcttac gttttaccag cagtcatcct tggtttgttg ggtgctcctg gtacagccat
    14401 ttggattcgt cgttacatga ttgacttgca atctcaagac tttgttcgtt tcgctcgtgc
    14461 aaaaggtttg tctgaaaaag aaatttcaaa caaacacatc tttaaaaatg ccatggttcc
    14521 gctggtttca ggaattcctg gtgccatcat tggggttatc ggtggtgcaa cccttactga
    14581 aacagtcttc gccttcccag gtatgggtaa aatgttgatt gactctgtaa aagcatctaa
    14641 taactctatg gtcgttggtc ttgtcttcat ctttacatgt atttctatct tctcacgtct
    14701 tttgggagat atttggatga ctattattga cccacgtatt aaattgactg agaaaggagg
    14761 caaataatgt ctacaatcga taaagaaaaa tttcagtttg taaaacgtga cgattttgcc
    14821 tctgaaacta ttgatgcgcc agcatattct tactggaaat cagtgtttaa acaatttatg
    14881 aagaaaaaat caactgtagt catgttggga atcttggtag ccatcatttt gataagtttc
    14941 atctacccaa tgttttctaa gtttgatttc aatgatgtca gcaaggtaaa cgactttagt
    15001 attcgttata tcaagccaaa tgcggagcat tggttcggta ctgacagtaa cggtaaatcg
    15061 ctctttgacg gtgtctggtt cggagctcgt aactccatcc tcatttctgt gattgcgaca
    15121 gtgattaact tggttatcgg tgtttttgtc ggtggtattt ggggtatttc aaaatcagtt
    15181 gaccgtgtca tgatggaagt ttacaacgtc atctcaaaca tcccacctct tttgattgtt
    15241 attgtcttga cttactcaat cggagctgga ttctggaatc tgatttttgc catgagcgta
    15301 acaacatgga ttggtatcgc cttcatgatc cgtgtgcaaa tcttgcgcta tcgtgacttg
    15361 gaatacaact tggcatcacg tactttggga acaccaacct tgaagattgt tgccaaaaat
    15421 atcatgcctc aattggtatc tgttattgtg acaaccatga ctcaaatgct tccaagcttt
    15481 atctcatacg aagccttctt gtctttcttc ggtcttggat taccgattac agtgccaagt
    15541 ttgggtcgtt tgatttcgga ttattcacaa aacgtaacaa ccaatgctta cttgttctgg
    15601 attccattga caacccttgt cttggtatcc ttgtcccttt tcgtagttgg tcaaaactta
    15661 gcggatgcta gtgatccacg tacacataga taggagtaga aatgacaaaa gaaaaaaatg
    15721 taattttgac tgctcgcgat attgtcgtgg aatttgacgt tcgtgacaaa gtattgacag
    15781 ccattcgcgg cgtttccctt gaactcgttg aaggagaagt attagccttg gtaggtgagt
    15841 caggatcagg taaatctgtt ttgacaaaga ccttcacagg tatgctcgaa gaaaatggtc
    15901 gcattgccca aggtagtatt gactaccgtg gtcaggattt gacagcttta tcttctcaca
    15961 aggattggga acaaattcgt ggtgctaaga ttgcgactat cttccaggac ccaatgacta
    16021 gtttggaccc cattaaaaca attggtagtc agattacaga agttattgta aaacaccaag
    16081 gaaaaacagc taaagaagcg aaagaattgg ccattgacta catgaataag gttggcattc
    16141 cagacgcaga tagacgtttt aatgaatacc cattccaata ttctggagga atgcgtcaac
    16201 gtatcgttat tgctattgcc cttgcctgcc gacctgatgt cttgatctgt gatgagccaa
    16261 caactgcctt ggatgtaact attcaagctc agattattga tttgctaaaa tctttacaaa
    16321 acgagtatca tttcacaaca atctttatta cccacgacct tggtgtggtg gcaagtattg
    16381 cggataaggt agcggttatg tatgcaggag aaatcgttga gtatggaacg gttgaggaag
    16441 tcttctatga ccctcgccat ccatatacat ggagtctctt gtctagcttg cctcagcttg
    16501 ctgatgataa aggggatctt tactcaatcc caggaacacc tccgtcactt tatactgacc
    16561 tgaaagggga tgcttttgcc ttgcgttctg actacgcaat gcagattgac ttcgaacaaa
    16621 aagctcctca attctcagta tcagagacac attgggctaa aacttggctt cttcatgagg
    16681 atgctccaaa agtagaaaaa ccagctgtga ttgcaaatct ccatgataag attcgtgaaa
    16741 aaatgggatt tgcccatctg gctgactagg aggaaggaaa tgtctgaaaa attagtagaa
    16801 atcaaagatt tagaaatttc cttcggtgaa ggaagtaaga agtttgtcgc ggttaaaaat
    16861 gctaacttct ttatcaacaa gggagaaact ttctcgcttg taggtgagtc cggtagtggg
    16921 aaaacaacta ttggtcgtgc tatcatcggt ctaaatgata caagtaatgg agatatcatt
    16981 tttgatggtc aaaagattaa tggtaagaaa tcgcgtgaac aagctgcgga attgattcgt
    17041 cgaatccaga tgattttcca agaccctgct gcaagtttga atgaacgtgc gactgttgat
    17101 tatattattt ctgaaggtct ttacaatcac cgtttattta aggatgaaga agaacgtaaa
    17161 gagaaagttc aaaatattat ccgtgaagta ggtcttcttg ctgagcactt gactcgttac
    17221 cctcatgaat tctcaggcgg tcaacgtcaa cgtatcggta ttgcccgtgc cttggtcatg
    17281 caaccagact ttgttattgc agatgagcca atttcagcct tggacgtttc tgtacgtgcc
    17341 caagtcttga acttgctcaa aaaattccaa aaagagctcg gcctgaccta tctcttcatc
    17401 gcccatgact tgtcggttgt tcgctttatt tcagatcgta tcgcagttat ttacaagggt
    17461 gttattgtag aggttgcaga aacagaagaa ttgtttaaca atccaattca cccatatact
    17521 caagccttgc tttcagcggt accaatccca gatccaatct tggaacgtaa gaaggtcttg
    17581 aaggtttacg acccaagtca acacgactat gagactgata agccatctat ggtagaaatc
    17641 cgtccaggtc actatgtttg ggcgaaccaa gccgaattgg cacgttatca aaaaggacta
    17701 aactaataat ggttttataa tttccatgtc aatttttatg ggaattataa aacttttttg
    17761 ttggactgat ttgaaaaact ttgaaagctt cctgaaaga
//
LOCUS       DAVBED010000046        17282 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBED010000046 DAVBED010000000
VERSION     DAVBED010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.046"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQ547_001575"
     CDS             complement(<1..692)
                     /locus_tag="VQ547_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2543405.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQ547_001576"
     CDS             complement(803..1057)
                     /locus_tag="VQ547_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543406.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQ547_001577"
     CDS             complement(1415..1948)
                     /locus_tag="VQ547_001577"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2543407.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQ547_001578"
     CDS             complement(1935..2261)
                     /locus_tag="VQ547_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543408.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQ547_001579"
     CDS             2495..4213
                     /locus_tag="VQ547_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2543409.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQ547_001580"
     CDS             4324..4671
                     /locus_tag="VQ547_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2543410.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQ547_001581"
     CDS             complement(4949..5785)
                     /locus_tag="VQ547_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2543411.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQ547_001582"
     CDS             complement(5798..6427)
                     /locus_tag="VQ547_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2543412.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQ547_001583"
     CDS             complement(6437..7078)
                     /locus_tag="VQ547_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2543413.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQ547_001584"
     CDS             complement(7224..8453)
                     /locus_tag="VQ547_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2543414.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQ547_001585"
     CDS             complement(8443..9609)
                     /locus_tag="VQ547_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2543415.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQ547_001586"
     CDS             9753..10766
                     /locus_tag="VQ547_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2543416.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQ547_001587"
     CDS             complement(10811..11230)
                     /locus_tag="VQ547_001587"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2543417.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ547_001588"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ547_001588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2543418.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQ547_001589"
     CDS             complement(12733..13611)
                     /locus_tag="VQ547_001589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2543419.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQ547_001590"
     CDS             complement(13627..15132)
                     /locus_tag="VQ547_001590"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2543420.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQ547_001591"
     CDS             complement(15147..15683)
                     /locus_tag="VQ547_001591"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2543421.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ547_001592"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ547_001592"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2543422.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ547_001593"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ547_001593"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2543423.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQ547_001594"
     CDS             complement(16942..17142)
                     /locus_tag="VQ547_001594"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2543424.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3786 c         3096 g         5178 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gtcgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBED010000047        16715 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBED010000047 DAVBED010000000
VERSION     DAVBED010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.047"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..484)
                     /locus_tag="VQ547_001595"
     CDS             complement(<1..484)
                     /locus_tag="VQ547_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2543425.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQS
                     Q"
     gene            complement(653..1966)
                     /locus_tag="VQ547_001596"
     CDS             complement(653..1966)
                     /locus_tag="VQ547_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543426.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYT"
     gene            complement(1959..2507)
                     /locus_tag="VQ547_001597"
                     /pseudo
     CDS             complement(1959..2507)
                     /locus_tag="VQ547_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2588..2650)
                     /locus_tag="VQ547_001598"
     CDS             complement(2588..2650)
                     /locus_tag="VQ547_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2543427.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(2819..3807)
                     /locus_tag="VQ547_001599"
                     /pseudo
     CDS             complement(2819..3807)
                     /locus_tag="VQ547_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3756..4883)
                     /locus_tag="VQ547_001600"
                     /pseudo
     CDS             complement(3756..4883)
                     /locus_tag="VQ547_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(5046..5930)
                     /locus_tag="VQ547_001601"
     CDS             complement(5046..5930)
                     /locus_tag="VQ547_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2543428.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(6042..6896)
                     /locus_tag="VQ547_001602"
     CDS             complement(6042..6896)
                     /locus_tag="VQ547_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2543429.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(6954..7712)
                     /locus_tag="VQ547_001603"
     CDS             complement(6954..7712)
                     /locus_tag="VQ547_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2543430.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(7774..7962)
                     /locus_tag="VQ547_001604"
     CDS             complement(7774..7962)
                     /locus_tag="VQ547_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2543431.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(8284..8850)
                     /locus_tag="VQ547_001605"
     CDS             complement(8284..8850)
                     /locus_tag="VQ547_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543432.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(9118..10797)
                     /locus_tag="VQ547_001606"
     CDS             complement(9118..10797)
                     /locus_tag="VQ547_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2543433.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(10889..11050)
                     /locus_tag="VQ547_001607"
     CDS             complement(10889..11050)
                     /locus_tag="VQ547_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543434.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(11734..12048)
                     /locus_tag="VQ547_001608"
     CDS             complement(11734..12048)
                     /locus_tag="VQ547_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543435.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(12014..12403)
                     /locus_tag="VQ547_001609"
     CDS             complement(12014..12403)
                     /locus_tag="VQ547_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2543436.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(12791..13585)
                     /locus_tag="VQ547_001610"
     CDS             complement(12791..13585)
                     /locus_tag="VQ547_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543437.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(13585..14592)
                     /locus_tag="VQ547_001611"
     CDS             complement(13585..14592)
                     /locus_tag="VQ547_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2543438.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(14592..15599)
                     /locus_tag="VQ547_001612"
     CDS             complement(14592..15599)
                     /locus_tag="VQ547_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2543439.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(15589..16614)
                     /locus_tag="VQ547_001613"
     CDS             complement(15589..16614)
                     /locus_tag="VQ547_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2543440.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         5230 a         3153 c         2261 g         6071 t
ORIGIN      
        1 cctgactttg tatatacttt gttattcttt cctcattaat agtgtctaat gcactagttg
       61 cttcatctaa aattacaata ctaggattat ttattaatgc acgtgccagt gctatccgtt
      121 gcctttgccc acctgaaata tttgacccca tctctgagat gatagtatta aatttcatcg
      181 gcatagccat gatttcatca tagatttgaa ctgctttaca aacttcctct atcttttgtg
      241 aagtaacttc gttctttaaa gttatattat caagaatact tcggttcaat aaaaatgaat
      301 cctgtggaac tactcctaaa ttttgactta atattttttt atctatttga ttaatattta
      361 caccatcaaa taaaattttt cctgtatcaa tcttatataa tcctgatagt atttttgata
      421 acgtactttt tcctgacccc gattgaccga ctagtgcaat tctctgtcct ggctcaatag
      481 tcaaatttaa attttctatt acaggagctg agtctttgga ataagagaaa gataggtcct
      541 taatatctat tctaccttct aaagaacact ttttaagacc attttcaaca ttctcttcat
      601 tttcaagcca gatatcattt actctattta agtatcctgc tgccaaaata tactacgtat
      661 aagcattaaa tattgagatt tctgaactaa ataaaattga tgccatcgtt tgaaatgcga
      721 caacctcacc caataaaatt tttccattta aaacattatc aagtccaaaa atcaatataa
      781 ttataggagc gaacaattga aatacattag tagctgaatt gtataaaata tgcacaatac
      841 ttcgtttttt atactttgtc aatacgtttt ttaaatactt agaccagttt tcatatattt
      901 catcttctaa tcccgatatt tttattgaag aaatagtatt taatgcttct gtttctactg
      961 agtaaatcaa tgattgttct tgtaattctc tattaaccgt atcatacatt atttttctag
     1021 tactaaacag aaacaaaaaa ttgattaaac tcaatataag agctataatt gataatgttt
     1081 ttgaactaag aaacatatat attacaacac ttagaatagt cccgatatct actactcccc
     1141 caacaacttg gttagtaaat agctccctaa aaccactaag actagaaatt ctgtataaaa
     1201 tatctccttt tgccctgagt tcaaaaaaac tatatggtag tttaagcaaa tgcttaaatg
     1261 taaaactttc aatatctcta ctaaaaaata tattagaaaa tagaattccc atactcctag
     1321 ccaagataga aataaggtac aaacaaagta gagaaaataa aattaaaaac gaggtttgaa
     1381 aagaaaatgt attccctaat gcagaattaa taaactttga agtcattact ggtacggaaa
     1441 gtattattaa gtaacttatt attgaaaata gtaacgtcaa aatcaatcga ccttttacct
     1501 ttgaaaaact agagaatact cttatccatg gagaaggaaa ctgcgacttc aaagattgat
     1561 aattttcgtt aggaaatgat agcagtacta tattactaaa atgttttgaa aactccttaa
     1621 actcataatt tatatatcct ttagaaggat ccattatata gaccttattc ttttttactt
     1681 tgtaaataac tacataatgt tgattatccc agaatgctat taatggtaac ggaagttcac
     1741 taattttatt tacatcttta acttgatatg agccagtatc aaaatttcgt ttattcaata
     1801 actgtttcaa gtcacctata ctataaccat ctctcccttt ttctatatca cgtcttaaat
     1861 ctagtaatgt ctctttgctt ttatagaaat gtagtatgga caagcagcaa cataaaccac
     1921 attctatttg agacatttgc tcaatattag gtacttttct agtcatcatg tcctcttaac
     1981 tccagtaata aaacattaag taatctatca tcttgttttc gagatatttc atagacaact
     2041 ccagatactc ctagcataaa agaaaatgta ttcatagtat tcaaatccgt acttaattct
     2101 ggtttgataa cctgagaaac gacattatca aaataaaaat ctatagattc ttttattaat
     2161 aggttttctt catctttcaa tattgcatca agacaactga tagtacctac agaaccgtga
     2221 cataaattca attctcttat tttttctaca ttagttaata cattttcaat tattgataaa
     2281 tcattattcc caatattagt tttatcgaaa atttcttttc tagctaataa aatgcccgga
     2341 gctccataac accaaaaatt aggaaaggaa tcattatgat ttcttcatat gtctttccaa
     2401 ttttttaata tattattgaa acatttatct tctttatata gtaattcctc tatacatttt
     2461 aatatatctg tactaggatt aatttcataa taatatgata attacattgc tactccagaa
     2521 taatcgtgtg ctaaacctgt tactgttata ttatctaatt gtgaaataca ataattaata
     2581 cactttttta aatgatgata atatccatca ccaaaaccaa aatcggtaaa aattttgaaa
     2641 ttttcttcat acttggactt cctttccgtt tttatttatt gtacaataaa taaaaacgga
     2701 tttaattttt gttgggaaaa tgggaaatta tgaaatcaaa acttggcatc acacttagaa
     2761 aagttcgtaa aggaaaacaa attagtctat gctctgtagc agatgaacat ctttcaaaat
     2821 cacaaatatc tcgttttgaa cgtggggagt cagagatatc ttgtattcga ctaatcaata
     2881 ttttagacaa attacatatt actttgtagg ggagtttttg gctatcgttg ctcaattgtc
     2941 tgattaaggt cctacccttg atgaaacaat tattatccat gttttcttta ttatagacaa
     3001 agtaagaaga cgtttctcga atgtagactt tatatttttt atgattttct tcttccataa
     3061 tatccaattg atagttggga atgaaaataa gaccgctctg tttgacaccg aaagacacct
     3121 tgatatagac gcccttatca actagcttct ctatttggtt ctctgcaagt tccacttcaa
     3181 attcacgaac ggtatctcat ttttccttaa atgtcttaaa ggcttcctca atctcttcag
     3241 tggatacttt atccttatct cgttcttctt ggaaagcatg gtactgttcc tgtaaattct
     3301 ctaatccttc tgaagcaacg acttccttat ttttaaaata atcttgaaaa aatttgacat
     3361 catataattt cttatcactt attttttgat gacccaaact tatcttttga ttattttctt
     3421 ccaggataaa agttacattt tttgttttaa gtcaatggtt agattcaatt cttttgcttt
     3481 tgttattaaa tcttctaaag aattgacacg gtttaacaaa aattctaaac gactttcaat
     3541 ctcttgctta gcaaaatgcg ttctaaaaaa ttcttcatca tatagatctc gtttgctgag
     3601 ttggcgccct cgaattggtt ttatcatcgt tctatctgtc atcaaaaaac ggctatgctt
     3661 ttgactaaaa tcaatctgaa catgcaactg ctttgctttc tctaaaaaat catcaaacga
     3721 tttagattgc tgaagcaaaa aataaagacg ttgtttcaat tcaaatttat gactagattc
     3781 cttatatttt ttataatctc gaaaagatca ggatttttag ctaaaactgc cttacgaaaa
     3841 tccttccaga actgatggtc aatctcatta gccacatcca aacgccaagc atcgatatta
     3901 aactcttcaa tccaataagt cgcaaccttt aaaagataat tcttgacctc tggattggct
     3961 gtatttagct taggcatata gtcctcgaaa ccaaaaacat gatagggtaa gtctctctta
     4021 ttaactagct tttcagttgt caatgggaat tgttgaatat ggaaccaatc cttataagca
     4081 gactgttcac catttttgac gacatttttt cattgaagag attgcgaacc aatatgatta
     4141 aataccgcat ccagcatgac tttcatgcca cgatgatgcg cttgatccac cagttcccga
     4201 aaggtctcct tgtctccaaa ataacggtca atttcaaagt aatctgtcgt attgtacttg
     4261 tgattacttg tagattcaaa gatgggacaa agatatagtc cagtaatacc caagtcttgc
     4321 aagtaattca tatgatcaat aatcccctgt aaatcaccac caaagaaatc atcgctctta
     4381 ggtgtgacag atgaatccca gtctaaagtc ccttctgggt ttaatagagc attgccattg
     4441 gcaaatcttt caggaaatat ctgataccat accgtatttg aaacccagtc aggaaccttg
     4501 caggcatcaa tctcatgaag ataaggcaac ttaaatccat tcccaattgc atgaagattt
     4561 tctagagaat tttccacaca ccctttatcg ccatacaaaa tattttgacc ttctgtatct
     4621 ctgagctcaa agagatactg gatacgtgca aagtcaactg acacttcaac ctgccaatgg
     4681 tcaaataagg taccagaagt tatcttgacc atttcttttg tatcctgata aaactcttcc
     4741 ataaagataa aagggtcccc atagtgcaag ttgatgcttt caatgtcccc tttcttagtt
     4801 cgaattcgaa tatggagttt cttatcctta taaagatagg catactccga ctcaggccta
     4861 tggtaaatag cactcaattc catcaatttg tctcctaaag tattcattca aattttacgc
     4921 aaacgttttc aaactcaata aatccagtat actatttttg taaactattt gcaaggaatg
     4981 tccgttgtta aaggaactat cttttaaagt atacaaaaag ccttaaaaaa ggctttctct
     5041 atatactaat cctctttcgg ttttgaaaat acttctactc gctgagctag gactttgatt
     5101 tctacaggta ggttatctga tttatctccg tcaacatctg actccaattc actatctgaa
     5161 gagattttaa tattacgcgc tttgatatac tcgatattat catttgcgac aacatcccct
     5221 tttaataaat caggaatgac ggataatttg gagaatatag aggcatcttt cagaatcaaa
     5281 atgttggcat agccgtcctt gttttcttca aagattttct tatcagcgaa gtaatttgtc
     5341 aaaaggacca aaacatggct agcttcacca acataatttc cattttctgt ctcaacctta
     5401 atgttaaaga cctgatctgt catgacagac ttcatggtat ttacagcata ggttaaaata
     5461 ccgaattttg ttttgtcctc tatttcaaca ttgtgaatcg cctcaggcag agaaccgata
     5521 ctaaagatat aaccaaaata gttgtcattt gctttaccga tatcaatctt attggttaaa
     5581 tcaaaatcca gttcgtcaat tgcgccatcg atgtcttgat tgatttccaa aagttttgta
     5641 atgaggttac ccgtaccgcc tgggataatc cctaacttag gaatgtagtc tctctcatca
     5701 atacctgaaa tgacttcatt gacagttcca tctccaccaa acacaaccac tgcatcatac
     5761 tgctcacgag aagcttcttc agcaaaatgt gttgcatcca gcgctttttc ggtaattttg
     5821 gtttcaacat attcaaagta ttcttttgct ttattctcca gcttttcttt gtaatccaaa
     5881 gccttctcgc caccagaagt agggttgata attaccattg cttttttcat tgattttatc
     5941 cttaatttta aacagaaatg tttacatttc gtcgtatgca agtaaatgta atcctattat
     6001 acaatgaaaa tacagaaaag agaaatctga cgtactggag attaatacgc ttttattcta
     6061 ttttcccatc gcctaactac atcctttaag ggttcatcca agtaagaata ggccttatcc
     6121 ttgatccaat caggaatacc gtaagctgcc tctgctatgt tacaagtgat tgctgcgaga
     6181 gtatcactgt cgccaccaag tgagatggca tttcttatcg catcttcgaa gtctctactt
     6241 tcaagaaagg cgataatggc ttgagggaca gtttcctgac atgtttcgtt aaaacgatag
     6301 ttaggacgga tttcatctaa agtttgagat agattgtaat cgtattcttt ttctatataa
     6361 tccttaattc gtcttttaca ctctgtaaga ttgtcgttaa ttgattgctc gtactctcta
     6421 caataaccac caaagtaaaa acgacataga aagatagcat cagctgtagc catagcgcct
     6481 ttgacacctt ctggatgatt atgagttacc tctgcagaaa gactcgtaag tcctctagat
     6541 gatggccata taccagtttt cgcataaaaa ccacagtcca tgatccaagc acatggagaa
     6601 atacgcatag ctgatccatt cccaaagcta ttataaggct cacggttatc gctgtttagc
     6661 catgcattaa accgagcacc gtaatcagca ttcggataca ttctgccata tttcttcatc
     6721 gcgtcaatga aatcgtcttt ttgtccacca ttcataattg cttctgcaac agcacaggtc
     6781 ataaccgtgt catctgtaaa aaagcagtcc ttccgaaata aaggaaagtc ctttgttttg
     6841 atattgttcc attcgtaaac agaaccgaca atatctccaa taattgctcc aagcatcaga
     6901 ttcctccttg ttcattttga tgctttttat attggttata taccatattt attttagaaa
     6961 acaacatcct gttggatttt aaaaatttca tttttttcaa aatagggttt taccatttct
     7021 ttccacctag ctctatgaaa attgattgat tttaaaggag atagggcata atttcccaat
     7081 gcataaccat catttacttc aacaacaagt gttctgccat cgcgagtaac accgatatct
     7141 agtccataag ctattggcgc atctttccaa catgatatcg cttcatcaat tacacttgca
     7201 tcaaattgtg catgataatc acctgtatag ggtcgaacat ctaatacgcg accatctaac
     7261 acaaaacaac gccattcagc tatgaattct acaacctcac taatccatat aggatagtcg
     7321 aaaggtagac caatacctat taaatcatgg gttccattaa caactcttcc agtaaagact
     7381 tttgaaccag ctttaggctt aataaatttt ccccaattat caggtatatt cacaatctct
     7441 cctaaaatac cagcataaat ctttcgacca taaaactctt taagctcaat aggatagtca
     7501 taaaccggaa cgtttaagcc catcattttt agtaatgctc tagtctccat tatataatct
     7561 acaactatat cttcacttgt taactctttt atttcagaaa aagattgata taaaataact
     7621 tcttctcctt gtaagtaggc acctacttga gcattgtatt tattaattga aacctcactt
     7681 ggtaatttac tttgtctaat ataaacaacc atttcatcac tcctatatca ctagtgttac
     7741 actgatttgt aaaaaataat agcaattttg ctcttatttt tttgagtaaa tagctcccat
     7801 aatatcatcg aaataatcaa cggtatttag gagtaattca ataacctggg actttgttag
     7861 tcgcattccc cttctatctc tagcatcttc tactaaattt tcaagtttct ctagattttt
     7921 atcatccaag ctaatcatta ttctattttt atcggttgcc attttcatca cctcaagtta
     7981 attctatcac aggtgtaaca cttgtgtcaa ctggctttta taatacatta gtttaaaagt
     8041 ggagaggatt tttaacacag taactttaaa tctttggtat taaaaaattt tcacaatatt
     8101 tatagaaata aaatctgtct caaatcagtt atcaaatcta gtataaatta tgagcggcta
     8161 ctctaatact ttccctctaa acaagaaaaa gacttacact caaggatttt cttccccccc
     8221 ttcgttataa cgttttgact cttttactag caaaggtata tactcacaag gaactttggt
     8281 tgactattga atctctccaa cttcttcttt aacatatcct tctacatctt caatctctac
     8341 aaacattggg tctaagtgac acaagaaatg ccaaacttcg atcccttttt ttctgtaaag
     8401 aatcgcttca ccgtcttcac ttccgaaaaa gcttctgtcg atttcatatc cgcggctttc
     8461 taagaagtct tttgctttac gatagttcgt ttctcttgtt tcgacatagg ttttaacttc
     8521 atggttgtta acgacatatg catcaatttt tgaatatcct tcgatcactc tatcattttt
     8581 gagggataaa tttgaaatct ctttccaaat aatgtttaca ttttcctcag gatcgaacat
     8641 aaatttagat aaaggaacaa tatttccgtt aaaaataatt tccatataat ccggtatgtt
     8701 tttaggatta aaatactcca cttcaaaacc atcttctgtt tccagagtgt atcccgggat
     8761 ttgagctaca aaggctttcc catcttctat ggaatcaaat gctactaaat ctttagaata
     8821 atcattttgg tacaattcca atataaccat cgataatctc tccattttca ttatcaggct
     8881 aatgtaaata agcacgtcac ctgaccaatt caggctctct gtatcatctc atcatatttc
     8941 ctacttactt tacgagtcct atacccagaa cacaccttat cgaccttcgg tctcacctcg
     9001 ttgcattggc tgaacatcta cttttacttc gctgatgctt caactcgtac aagcagtgat
     9061 accgcctcag cgtgatgcgt cagtgggact caaaaggttc ggggaacctt ttgaggatta
     9121 actacgtttc tctaataaac ttacacattc aacttgttca tcattgtcca aacctatgtt
     9181 gagattttct tctataattg gtagcttaaa agtaatggat tttagccatt gtccgttaga
     9241 ttgtttttct tcataaactt gaatttcaga aatcaaagct gaaattaact gcctacgctc
     9301 tacatcattc atgactttat agagcttatc aaaatagatc agaaccttat atatgttatc
     9361 tcctgtaagc ttttcagctt caatagtctg tttctttgct ttcgcatcaa ttagtgatga
     9421 ttctaattca tctactttgt catacatacg atatagtcta tcatctaaat cctgtttcct
     9481 tctcttataa tgcttatctt caacatctaa attatctatt tcctcaatta gcttaaactt
     9541 tgtagaatga ctctttctca attccttttg gtaattatct atttcttttt ctatttcaga
     9601 ggtatccacc ttcatgttga ttttttcttg catcatagaa gcaaatttcg gattacttac
     9661 tatcttgaca atcacctctg caacagcatc atctaacaat tcttctctaa tttgcttact
     9721 gaatgtacac ttatgacctc ttatcatctg cctatggtta caaccatagt aataaaaatc
     9781 tttatacttt gtgccatctt tctttttctt gatacacttg ttcccaaaca ttcccactcc
     9841 acatatcggg cattttacaa ttccagaaag caagtgtgtg cgtgtatctt ttcctttatt
     9901 cacatgctca tatttctttg cttgagattt tagcttaacc tgagcagctt gccaaacttc
     9961 atcggaaact atagcttcat gtatcccttc agatattaga tattcatctt gttcaacctg
    10021 cttatattca tttcttgtac catgaacttt ttctaaagtt cttcttccaa atgctatttt
    10081 cccattatat acaggattct ttaatatctt tcttataaga cctgcatcaa acaaaggatt
    10141 cttaccattc tgtcttggga tttttctaat tccatgattc tctaagtatt tagatatccc
    10201 attggctcct atcgtagtat ttacatactg gtcgaaaatc gttcttattg caactgcctc
    10261 ttcctcattt ataaacagct tgccgtcttc aagtttatat ccatacggag caaagccacc
    10321 attccatttt ccttcccttg ctttttgaat gcgaccttcc attgtttgaa tacggatgtt
    10381 ttctctttct atttcagcca cagctgataa aacagaaatc attagtttcc cagcatcttt
    10441 agatgaatca atgccatctt caacgcagat aagattaact ccataatcct gcattatctg
    10501 aagtgtagaa agaacatcag cggcatttct tgcaaatctt gataacttaa acacaagaac
    10561 aaaagatact ccatcttttc cagattttat atcttccatc attcgattga actgtattct
    10621 accttcaata gacttgccag acttcccggc atcttcatac tctccaacaa tttcataatc
    10681 gttgtaaata gcaaaagctt tcattcgtga tttttgtgcc tctaacgaat acccctctat
    10741 ctgtattgac gtagatactc gtgtatagag gtatactttt attttttctt ttgacatagt
    10801 attaatctca atataatttt tctatatcat atataatttt tttaatttaa gtttggacta
    10861 tcatttcaag tatattataa cacttttatt agtccgtctc aatttgtgtt tttgccatgt
    10921 caaaactatt tttcatctct tgattttttg ctggcgttgg atcgggtaga ttatctaaat
    10981 ctaaagcacc agcatatttt gcaatcagat ttgctattaa atcagccaat ccattccagt
    11041 cattgtccaa tatatacctc ctctaaagtt ttatatctaa taattatttg tttaattaag
    11101 ttttttgaca ttgacaagtg ctttggatta gcaacatagg aatctcacct ccgcctctat
    11161 tccggatgag ccggcttcaa ccttagaagt atcattatcc tcattttctt catagcggat
    11221 agggtatccc tccctatatt caaactctta cttatcgctc actttctttt tacttagcag
    11281 aacttttttt gccgaattat tcagccgaaa gatcttgacg gataggttat tacgctccaa
    11341 aaataattaa cgtcttgtct tggtctattc aattgttaag gttcaaaatt tatcgagagt
    11401 tattaatctt tttaaaattt gaccatcaga aaatatttat cttaatgtaa caaaattcta
    11461 taaattaccc tcttatactt aacagtgaaa agaagtcttt cttggtaacc aattttgaaa
    11521 tagaatttgc ttatataaaa aggtcaaatt cccactgcat aagtagcagt gaaaattaga
    11581 ccctcttggt aactgtcatc taaaagtctt ctagcatttc tttaattttc taatcgcctt
    11641 taaagtgtca tatttatatt tttttatctc tggcatactt tgataccttt ttagacttaa
    11701 agtctttaat agtgcctttc cacctctttt tatctataaa gattctccta catcataatt
    11761 cattttttta tttaaacctt tctgtcttag tttgtcttta tcttcttcat accattttaa
    11821 gattgtcaca tagtggtttt gataggtctt accactgctt tccatgtatc tggatagttt
    11881 atttatcatt atatctgtgt gtgagtttaa tttttctttt agatttttat attcttcttt
    11941 gcttaacctt acatttttga attctccata aaaaatgggg gtggactttt tatctatctc
    12001 tccctctctc tctttatcta tctctatatc tttccatgta attccaatct ggagtacctc
    12061 tactgtctat cggtaattta attttgatat ctggcaatac tgtgctagat atttgatctt
    12121 tatattcagt attttttaaa gcttgcctaa taattgaagt taaatagaat gctacttctt
    12181 tattcaattc tttatttttt aattttaaac aatgaatttt catatctagg cttgctttat
    12241 atttatgata aaagactgct cctaaaaatg aaacagatat aaaattttca aaaactctat
    12301 aatttttatc atctatatct tcgtagtaac ctaagatacc attgtcaata tttgtagcac
    12361 taattctagg agtttttcca tcgagtaaat atctttttgg aatagatgag cctgttggta
    12421 cttgactcga tttccccttt ttttcggtaa taaatatttc tttttatttt gttgtctgat
    12481 atttttccta cctgtccttt gtaggatgag tattttctag attttcttga ataacttttt
    12541 acttgaagtt ttagcttttg aactagtcgt tgtactttct ttttgtttat tatcagtcct
    12601 gatcttttta atattgctgt tattctctat atcctatttt tcattcatga tattctttta
    12661 ctaattttat cttaaattct gtgctgtatt tgccattaaa aaactgacct cctttagtta
    12721 gttttttggc ctaacttttg agggtcagtt caaaatttgc gacttttaaa tgaattccaa
    12781 tattcaatta ttaagagcta acatggtgct tgccaatagg aatcattaga ggcgaattgg
    12841 aaatagggtc acgtataatt tttgcttcaa gattaaagat atctttaact agtttatcat
    12901 ttagtatatc ttcaggcttt ccctctgcaa caagtttacc ttctttaatt gcaaataggt
    12961 aatcagcgta tcttgctgtt agatttatat cgtgcaaaat catgcaaatg gttgtcttat
    13021 atttttggtt tagatcagtc aagaggtcta atagttctat ttgatatgag atatccaagt
    13081 aagtagttgg ctcatctaaa agtaggatac ttgtatcttg ggctagggct agagctatcc
    13141 atactctttg cctttgaccc ccagaaagtt cttcaactag gttatttgct agatcttcaa
    13201 cattggcctt aaccattgat ctgtttatta tttcaaggtc atcttttcca agactcttaa
    13261 aaggctttct gtaggggaaa cgaccacggc ttacaagatc agctactgtt attgattcag
    13321 ggattattgg agattgaggt aatatagcta tgtgttttgc taaatctttt tctttataag
    13381 aattaattga tttattatca agcaatactt ctccctctaa tggctttata agtcgagaca
    13441 aggttttaat gagtgttgat ttcccacaac catttgaccc aataataact gatatttttt
    13501 cttcaggtat ttttatattt atattttcca agattatttt ttcatcataa ccgcaggtaa
    13561 gattatttga ccacagacct ttcattatat attcctcctg ttcattttta ttagtaagta
    13621 tattaagtat ggtgaaccta acaagccagt tacaacacct actggatatc tagctggtaa
    13681 aatattttga gagaatatgt ctgataacaa aactagtaaa attccaacca atccagctaa
    13741 tattgggctt cttttcttgc caatatttaa ggctatggga ccagctaaaa aagatataca
    13801 agctattggt cctgtaattg aagtagaaaa agcagttaaa gatacagcgc aaaaaattaa
    13861 aacaagcctt gaaagctcgg gatttgctcc aagtccgatt gctatttctt caccaagttc
    13921 aataatttct agtcttttat taaaaaataa aactaatata gtagcaataa tacttactat
    13981 tagaacaaga ggtatgtcat ctaactttgt aaaagataaa gagccactga gccatctcat
    14041 aacttcttgt aattcatatc ttgctacttt caacaataaa aatgaggtgc ctgctcttgt
    14101 gacagcttga aaaccaatac ctaatattat cagtcttgct gctgaaaaac catctttttt
    14161 agctagtaaa aataatatta aagatgatgt tagtccacaa gttattgaaa taattccagt
    14221 agttaaacta tttgttttta ataccaatat gcaaaagacc gctgcaatag atgaagaact
    14281 tgtgacaccg attatatcag gacttgcaag aggatttctt aacatagttt gaaagataaa
    14341 tcctgccaat ccaaaagacc agccagctat aattcctgct aataattttg gtaatctaat
    14401 ttccataatc gaaaaactag ctccaggaac agtttcacta tttaagactt taatcaaagt
    14461 tgaaaaagaa taactttcat ctccgataag taaaatgaaa aatgatagac tgattattat
    14521 taataaaaat agtgaggaaa atagtgttat tctatttttt cttttttgaa tacctataat
    14581 taaattttgc attagttatt aacccctcta tttttcatag ttacataaat aagtactgga
    14641 cccccgatta ttgcagtaat tatccctact tcaatttcac ctggtttacc taacatacgg
    14701 ccgattatat cacatataag caagagctct gcacctataa aagatgaaga aatggtcatt
    14761 gtgcgtatat ctttgcttat aaataagcca caaaagtgag gaactataag acctacgaag
    14821 ccaataggtc caccaattgc agtaatactt gaacataaaa gcacacttgc aattattgca
    14881 agtgatctta tcctattaac attaactcca agaccaacag ccatttcatc acccatagct
    14941 aaagcgttta aatctgatga aataaatata gctatcaagt gacctaaaat tataaaaggt
    15001 agtagtgtag atatagaaga taatgtagct gctccaaggc tacctatttg ccaaaatcta
    15061 aatttgtcta agacgttatt attcggtaaa attaaaaaac ttacaaaact gcttaaagcc
    15121 atactaacac aagttcctga taaggctagt tttatagggg taaggcctgc ttttccgctt
    15181 acagcaatcg cgtatacaaa aattgcactt actaagccac caatgattgc aaaacttata
    15241 tggcttatgc ttgatgaaat tcctaaaaaa gaaagaccaa ttactacact aagacttgct
    15301 cctgtgttta taccgagtat acctggatca gctattgggt ttctagtaac tgattgcatc
    15361 aatacaccgc ttatggcaag actagaacct gctaaaattg caaaaatagt tctaggtatt
    15421 cttttatata taattgattt aataaaatca tcatttgtat tgcccattcc aaaagttgct
    15481 aaaaaatctc tgatattaat ttcttttgtt ccaagcttta atgacaaaaa tattgtaata
    15541 agaagaccta ggcagattac aaaaattatg cctaggttta tttgtttttt atttcgcatt
    15601 tttgcatgca tttcctaaaa gatttaggta ttcttcaata gtatagttta ttgaaagtgg
    15661 tgttggagtg catgaggctg ctaacggtgt attatctgga attacagcaa cggcaccatt
    15721 tttaattgca tttattttac ctaaaagagg atctttttgt aaagcttcaa gagttttatc
    15781 atcaccataa gttatgatta catcagcatc atttatctta tttgcttctt ctgcagaaat
    15841 ttcctttgca aaactatctt cactctcaaa ttcttttaat gattcaggga aaactagacc
    15901 taaatctgtt aaataatttg ctcttggatc tttgctagta taaatccaga attttgatgt
    15961 atctgcagca ttaatcatag taaataatac tttttttcct ttgatttttc ctttgatttc
    16021 tggatgtttt tctaattctt tggatatacg agcttcagta tttttgatta actcatcacc
    16081 ttctttttcc atacctaagg cttttgaatc aattttaatc atatctctcc ataaagtttg
    16141 ccaaggttta gatttgtatg ctgctacagg agcaattttt gatagagtgt cataatcttc
    16201 tttagttata ccagaataac ctgctaagat aacatctggt ttagaatttg atattgcttc
    16261 aaagttaagt ccatccaaat cgtcaaatag gttagcttta ccatttagtt ctttgatttt
    16321 ttcttctgtc catggtaaaa ctcctttatc agcacttaca ccgtaatttg cttttgaaaa
    16381 tccaacagga actattccta aagctaatgc tacatcatga tttccccaag caatagttgc
    16441 aactctttca ggttttttat ctaatatagt ttgaccgaaa gcatgatcta aaactatttt
    16501 atcaggcgca tgctctttag aagtattttc ttcattttta acagaattag aagaacaagc
    16561 gctaaaaact atacacatag ctaaaatagc tattagaaaa aatttgtttt tcataaaaac
    16621 tccttaaaca tatttcaagt ctattgtatc gataataatt atcattgtca atagatacag
    16681 ttacaaattt aataatataa ttttttcaaa aaagg
//
LOCUS       DAVBED010000048        16132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBED010000048 DAVBED010000000
VERSION     DAVBED010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.048"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQ547_001614"
     CDS             145..6831
                     /locus_tag="VQ547_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2543441.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQ547_001615"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQ547_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQ547_001616"
     CDS             complement(8146..8505)
                     /locus_tag="VQ547_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2543442.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQ547_001617"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQ547_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQ547_001618"
     CDS             9537..10094
                     /locus_tag="VQ547_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2543443.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQ547_001619"
     CDS             10087..10341
                     /locus_tag="VQ547_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543444.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQ547_001620"
     CDS             10353..12407
                     /locus_tag="VQ547_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2543445.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQ547_001621"
     CDS             12586..13446
                     /locus_tag="VQ547_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2543446.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ547_001622"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ547_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2543447.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQ547_001623"
     CDS             14387..14953
                     /locus_tag="VQ547_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2543448.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQ547_001624"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQ547_001624"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2543449.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBED010000049        15735 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBED010000049 DAVBED010000000
VERSION     DAVBED010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.049"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            9..89
                     /locus_tag="VQ547_001625"
     tRNA            9..89
                     /locus_tag="VQ547_001625"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VQ547_001626"
     tRNA            94..164
                     /locus_tag="VQ547_001626"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VQ547_001627"
     tRNA            179..251
                     /locus_tag="VQ547_001627"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="VQ547_001628"
     tRNA            265..336
                     /locus_tag="VQ547_001628"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="VQ547_001629"
     tRNA            346..429
                     /locus_tag="VQ547_001629"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="VQ547_001630"
     CDS             536..1813
                     /locus_tag="VQ547_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2543450.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /locus_tag="VQ547_001631"
     CDS             1889..3373
                     /locus_tag="VQ547_001631"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2543451.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="VQ547_001632"
     CDS             3434..4714
                     /locus_tag="VQ547_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2543452.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="VQ547_001633"
     CDS             4718..5338
                     /locus_tag="VQ547_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2543453.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6646
                     /locus_tag="VQ547_001634"
     CDS             5504..6646
                     /locus_tag="VQ547_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2543454.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7071..7496
                     /locus_tag="VQ547_001635"
     CDS             7071..7496
                     /locus_tag="VQ547_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2543455.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7507..7875
                     /locus_tag="VQ547_001636"
     CDS             7507..7875
                     /locus_tag="VQ547_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2543456.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            7982..8626
                     /gene="pcp"
                     /locus_tag="VQ547_001637"
     CDS             7982..8626
                     /gene="pcp"
                     /locus_tag="VQ547_001637"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2543457.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8654..9511)
                     /locus_tag="VQ547_001638"
     CDS             complement(8654..9511)
                     /locus_tag="VQ547_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2543458.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9641..10783
                     /gene="tgt"
                     /locus_tag="VQ547_001639"
     CDS             9641..10783
                     /gene="tgt"
                     /locus_tag="VQ547_001639"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2543459.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            10884..12701
                     /locus_tag="VQ547_001640"
     CDS             10884..12701
                     /locus_tag="VQ547_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2543460.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12854..14005
                     /gene="nagA"
                     /locus_tag="VQ547_001641"
     CDS             12854..14005
                     /gene="nagA"
                     /locus_tag="VQ547_001641"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2543461.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14168..15226
                     /locus_tag="VQ547_001642"
     CDS             14168..15226
                     /locus_tag="VQ547_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2543462.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15377..>15735
                     /locus_tag="VQ547_001643"
     CDS             15377..>15735
                     /locus_tag="VQ547_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2543463.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMK"
BASE COUNT         4604 a         2783 c         3637 g         4711 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa gggactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattaag aaagtgtagg gtagtatgtc
      541 ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt
      661 tgaagttata aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt
      781 atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgtcc gaaatccaag catttgctct gaatggggat gaggttatta tttaccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gatttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gttacttatc caaaggtaga tttggacttt gacaaattga aagatgcttc
     2041 ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcggatgtgc ctggtactga gattatcgtc ttttatccaa agggtggtgt
     2401 cagcaaggta caagagttgc aaatgaccac tcagaatggt gacaatactc atgttattgc
     2461 tattgatggt aattttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tcttcgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac
     2641 tggtgaaatt gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat cggcctacca gttggcaagc taatctgtgc
     2761 ttcaaatgac aataatgtct tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca gctgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacagc ggcagaaatc aagcgtgttt atgagtcaga
     3061 ttcttatatt gaggatccac atacggcggt tgcctcagca gtttatagaa aataccaagc
     3121 ggttactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggtttg acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tccaattcgt cacaagacaa cagtggcagc tgctgacatg caagcagcgg ttgaggctta
     3361 tttaggactt taagacagag ggagcaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtttgggagc cttgattcgt gcaacgcata atccacgtct
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagctaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggtg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg tacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 catgtggtgt atccgcattg ggacaggata tctgatgggt attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa aatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacactttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttgacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta atctagtttg
     5401 ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt
     5461 gtgttatgat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtcaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc
     5941 tccaaaagaa gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt
     6001 ggcaccatct acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt
     6061 tgcagaagaa gctcctcagg gaacgactcc agctgagaag caggaaacac aagcaagccc
     6121 tcaagctgca tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc
     6181 atcaaatgga gctacagcag cagtttctac ttatcaacca gaagagacga aaataatttc
     6241 aacaacttac gaggctccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga
     6301 aaatgcaggt cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg
     6361 cattacatcc tttagcggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc
     6421 tatcgacttt atggtaccag aacgttcaga attaggggat aagattgcgg aatatgctat
     6481 tcaaaacatg gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc
     6541 attcgatagc aaatatgggc cagctaacac ttggaaccca atgccagacc gtggtagtgt
     6601 gacagaaaat cactatgatc acgttcacgt ttcaatgaat ggataaaccc gacttggtaa
     6661 catcattttg acgaatgaga tctagctttc gtgatgggaa gcgattctcg ttcgtttttt
     6721 ctttgtcata ctcttcgaaa atctcttcaa accacgtcag ttttatctga aacctcaaag
     6781 ctgtgctttg agcaacctgc gactagcttc ctagtttgct ttttgatttt cattgagtat
     6841 caatttgaat ggaaaatgga aagttatcat cttgtaataa tctaagcaac attcttgcaa
     6901 tctattttat agtagattga aactagaata gtacacaact gcttctaaaa cattgttaga
     6961 aatcgatttg actgtcctga tcgatttgtc ctgctcttat ttcatttcac tatactttat
     7021 attataattg attggtcaac tattgataag tcaatggata ggaggaagaa atgatagaga
     7081 ttcaagattt actgtatcaa ctccgcttgt ctgagcaagc gagtacgcaa ttgtttgaaa
     7141 aaaggcttgg gattagtttg acacggtatc agattttact gtttttgctg gagcattctc
     7201 cttgtaacca aatggcggtt caggagcgtt tgaaaattga tcaggctgct ttgacacggc
     7261 atttcaagat tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc
     7321 gggaagtgtt ggtagaggct gcgaagtatg ccaaggagca gttagtggtg aatccccctc
     7381 tgcaacatat caaggttaag gaagagatgg aaagtatctt aacagagttt gagagaacag
     7441 aactcagccg tttattaaat aaattggttt tgggtattga aaatatagaa atttaaggag
     7501 aaatagatgt caattattac aattatttta acaacgatcg ttgctttgga gcatttttac
     7561 attttttatt tggaaagtat tgctacgcga tcagatgcga ctagtcgtgt atttaatatg
     7621 gaaaaggaag aattggctca tccgtcagta agttcattgt tcaaaaatca agggatttat
     7681 aaggctctgc taggagtctt tctctggtat ggcatttatt tctcacagaa tttagaaatt
     7741 gtgactattt ttgtcttatt tgtgattggt gctgcgactt acggctcttt aacagcggat
     7801 aaaaaaatta ttttgaagca aggtggatca gctattttgg ccttgattag tattttactc
     7861 tttaaataca cttgaaggtc gattttaatc tcgctaatcc tttttaatcc agaataaggg
     7921 aaatatgtta tacttgtttt taagaaaaaa gtctcattga attggttttg aggagttaga
     7981 aatgaaagta ttagtgacag gttttgagcc ctttggaggg gaaaagggca atccaacttt
     8041 ggaggccatt aaaggtttac cagctgaaat ccatggtgct gaggtccgtt ggctagaggt
     8101 gccgacagtt tttcacaaat ctgctcaagt attggaagaa gagatgaatc gttatcaacc
     8161 tgactttgtc ctttgtattg ggcaagctgg tggaagaact agtgtgacac ctgaacgagt
     8221 ggccattaat caagacgatg cacgcatttc tgataacgaa gataatcaac cgattgaccg
     8281 tcccattcgc ccagatggtg cttcggccta ctttagtagt ttgccgatta aagcgatggt
     8341 tcaagctata aaaaaagagg gcttaccggc ctctgtttcc aatacggcag ggacttttgt
     8401 ctgcagccat ttgatgtatc aggctctcta tttggtagaa aagaaatttc catatgttaa
     8461 ggcaggtttt atgcatattc cttatatgat ggaacaggtg gtgaacagac cgactactcc
     8521 aactatgagt ttagtggata ttcggcgagg gatagaagca gcaatcggcg ctatgataga
     8581 acatggagat caggaactca agttggtagg cggagaaact cattgataga aaaaagcttg
     8641 aggggaaaaa ccttcaagct tttggacgtt ttcgagccaa tactgctcgg taaaacataa
     8701 ttttagtgca ttggatataa ggtaggagtg aaaaactagc aatgccaaag gtaatccaat
     8761 tgaggaagta ccaaggaaga agctgtaaat ctaggacaaa gtgctggaac ttgtagccct
     8821 tcataaagga acggctagtt tttaggattc gtcttggtgg gacctgtcct aggtctagac
     8881 tataacagag aagaaattcc acctgtgaat aggcataata ctgtggaata tagaggatat
     8941 ttcctacaat gatcaagatg agacttgcaa gaaagtagag tccaaagacc atgaggaaac
     9001 gctcggtttc aactgatgag agatctagat ttggaaactc aggatgtagg gtgacgaatt
     9061 ttttggctaa aaagctacta taaaagagga ggtaaatccc aagtaaatta gggatactcc
     9121 ataaaaagag atagaaacgt ttgagaagta gggtcaaaaa ggtttgagaa aagcgctcct
     9181 catcaaagag agctaggctg ttttttacag atggctccgt tttagaatct ttcatgagtg
     9241 tcagtgttgc atagacggaa ctggtcaaaa gaatagtccc gataaaggag actagtagag
     9301 gaaagaggta ggtttgaagt atttggccaa gtatgctgaa aaatggctgt tctaaaacag
     9361 tcccgtggat ccgagataag ggattaagaa aaccagataa gatgaccagc atactgggaa
     9421 ggatatagag gagaaagaga cggggggtgt cagcctgaaa atgttttgac tcctgacgaa
     9481 ttgtttttaa atcaattttt ggatagttca ttctcttatt ataccatagt tcttatacat
     9541 agttcgtgac agttcctact ttttttgata aaatcataca gtgtgtcctt gggcacactg
     9601 tatgaactgg gactgtcttt cccagcttcg gaggtaaaaa atgtcagatt caccaatcaa
     9661 atatcgtttg attaagaaag aaaaacacac aggagctcgt ctaggagaaa tcatcactcc
     9721 ccacggtacc tttccgacac ctatgtttat gccagttggg acacaagcca ctgtcaaaac
     9781 tcagtcacct gaagaattga aggagatggg ttcgggaatt atcctatcaa acacctatca
     9841 tctctggctt cgccctggag atgaactcat tgcacgcgct ggtggtctcc acaagttcat
     9901 gaattgggac cagcctatct tgacagatag tggtggtttt caggtttatt ctttagcaga
     9961 tagccgtaat atcacagaag aaggagtaac ctttaaaaat catctaaatg gttctaagat
    10021 gctcctatcc ccagaaaaag ccatctctat tcagaataat ctgggttcag acatcatgat
    10081 gtcctttgat gaatgtcctc agttttatca accttatgac tacgttaaga aatcgatcga
    10141 gcgtaccagc cgttgggctg agtgtggttt gaaggctcac cgtcgtccac atgaccaagg
    10201 tttgtttgga attgtgcaag gtgcaggatt tgaagacctt cgccgccaat cagctcacga
    10261 tcttgtcagc atggatttct caggctactc tatcggtggt ttggcagtgg gagaaaccca
    10321 tgaagagatg aatgcggtct tggactttac aactcaactg ctgcctgaaa ataaacctcg
    10381 ttatctgatg ggtgtgggag cgccagatag cttgatcgat ggggtcattc gtggggtgga
    10441 tatgtttgac tgtgtcttac cgactcgaat tgctcgtaac gggacttgta tgaccagtca
    10501 aggacgtttg gttgtgaaaa atgcccagtt tgctgaggac tttacgccac tggatcctga
    10561 gtgtgattgc tacacatgta ataactatac acgcgcttac cttcgtcacc tgctcaaggc
    10621 tgatgaaacc tttggtatcc gcttgactag ctaccacaat ctttacttct tgcttaacct
    10681 gatgaagcaa gtgcgacaag ccatcatgga tgacaatctc ttggaattcc gtaagtattt
    10741 tgtggaaaaa tatggctata ataagtcagg acgtaatttc taaaatggaa ttgatataag
    10801 ctaaaaatcc taagttttct cttaggattt ttcttctttt tttgatagaa taaagtgtac
    10861 aatgaaagga agaataaact cgtatgcgca ttaaatggtt ttccttgatt aggattatag
    10921 gtttactttt ggtactcttg tatcacttct ttcagacgat ctttcctgga ggatttttcg
    10981 gggtagatgt ctttttcaca ttttcaggtt tcctgattac agctctactc attgaagaat
    11041 tttctaagaa caatgagatt gatttgatag gattttttag aagacgcttt tatcggattg
    11101 tgccacctgt ggttttgatg gtcttggtga ccatgccttt tactttcttg gttcgccaag
    11161 actatgttgc tggaattggt ggccagattg cgggcgtctt aggctttatg accaacttct
    11221 atgaactctt aacaggtggg agttatgaat ctcagttcat tcctcatttg tttgttcata
    11281 attggagttt ggcagttgag gttcactact atattctttg gggattggca gtttggttct
    11341 tatccaaaca agctaaatca aatggtcagt tgaaggggat gatctttctc ttatctgcta
    11401 ctgccttctt gatcagtttc ttctccatgt ttattggtag ttttctagtg acctcttatt
    11461 cctctgttta tttctccagt ttaactcatg tctatccatt ctttttggga agtatgttag
    11521 caactattgt aggcgttcgt cagacgactt ccctcgtcaa gcagttggat aaaatctggg
    11581 atttacgaaa gactttagta gtttttggag gaggctttgg tttcctagtt cttttgactt
    11641 tctttgtcaa attcacttat ctttttgcct atcttatcgg cttcttgctt gccagtcttg
    11701 cagctcttgc catgattctg gcggcgcgtg tcttacatga aaagacacat catatacagg
    11761 agccgaagat tatcagcttt ttagcggata ctagctatgc ggtttatctt ttccattggc
    11821 ctttctatat cattttctca cagttgacat caaatcttct tgctgtatta ctgactctga
    11881 tttgttctta tggctttgcc agtctgtcat tttatgtatt ggaaccttgg attgcaggca
    11941 agaacacacc tattttacaa actcttcgtc ccctgcctta tattcacgca attcttgcag
    12001 caggtacagg aatcttgacc ttcattgtct gcatggtgac cttgttggca ccacaagtgg
    12061 gagcgtttga gacagacttg actgtcaatg gcttgaagca agctgcaaca aatattggcc
    12121 agaccaaggt gatggcagaa cgggcagatg caaacagttt gggaattgct gatggcacta
    12181 tgttaattgg tgactcagtg gctttaaggg caaatacagc actacagaca gctcttcctg
    12241 gagcacagat taacgcgcag gtcagcgtaa caaccaagac cgcaaatgaa atcatgctaa
    12301 ataatagcca gaataaattt ttacctaaga cggtggtcat tgcgactggg gtaaataatc
    12361 ctgagaatta caaggatgac tgggacagta tcgtgaaaaa tcttcctaag ggacaccata
    12421 tgattttggt gactccttat gagggagata agacaaaaga gacctatgcc atcgttgaga
    12481 aggctgctgc ctatatgaga gaattggcag agaagacacc ttacattacg atagcagatt
    12541 ggaatcaagt tgcgaaagag catccagaaa tttgggctgg aacagaccag gttcatttcg
    12601 ggagtgagag tagcactatc gaagcaggag caaaattgta tgcagatacg attgccacag
    12661 ctttgcagac agctcaagac aagccggtta aatcaaaata acttgtatta aaaaagagaa
    12721 gagttggaga aatccagctc ttttaaaata tctccaaaaa ataggtctat accatttaca
    12781 aataaaaaag aaaggtttat aatgtaattg acataataaa ttgtagaatc aatcttttaa
    12841 ggaggttaac attatgccta actatattaa agcggatcag tttttctacc cacacggagt
    12901 tcgtcgaggt ggttacttgg aacttgtgga cggcaagttt gggaaacatg tagagcagat
    12961 tcctgaaggg gctgaggtga ttgactatac aggttatagc attgccccag gacttgtgga
    13021 tactcatatt catggatatg caggtgtaga tgtgatggac aacaacattg aaggtacatt
    13081 gcatactatg agtgaaggac ttcttagtac cggtgttacc agtttcttac ccacaacttt
    13141 aacagccact tatgagcaat tgcttgcagt cactgaaaat cttggaaacc attataaaga
    13201 agcaacaggt gctaagattc gtgggattta ttatgaaggt ccatatttca cagaaacttt
    13261 taagggggca caaaatccaa cttatatgag agacccgggt gttgaggagt ttcattcttg
    13321 gcaaaaagcg gcaaatggct tgcttaataa aattgccctt gcaccagaac gtgatggggt
    13381 ggaagacttt gttcgtacag ttacgggcga aggtgtgacg gttgctcttg gacattcaaa
    13441 cgcgactttt gatgaagcca aaaaagcagt cgatgctgga gcgagtgttt gggtgcatgc
    13501 ctacaatgga atgcgtgggt tgactcaccg tgaattgggt atggttggag ccatgtacca
    13561 attgccacat acctatgcag agttgatctg tgatggtcac cacgtagatc caaaggcttg
    13621 cgaaattctt atcaaacaaa aaggaacaga aaacatcgct cttatcacag actgtatgac
    13681 agctggggga ttggaagacg gagattatat gttgggagaa ttcccagttg tcgttgcaaa
    13741 tggaactgca cgcctcaaat cgacaggtaa cttggcaggt tctatcctca aactcaaaga
    13801 tggtttgaag aatgtggtcg aatggggaat tgcgaatccg catgaagcag tcatgatggc
    13861 cagcttcaac ccagctaaat ccgttcacat cgatgacgtc tgtggccaaa tccgtgaagg
    13921 ctacgacgct gacttcatcg tattagataa agatttggaa ttggtagcaa cctacctaga
    13981 tggtgtgaaa cgttatcaag cataagagag aaggcagaag ttagagacta gcttctgctt
    14041 ttttatacag ggtactttac tggtaaataa aaagttaaaa aaatcacaaa aaaagcttga
    14101 agaaacaaag aaaaaggctt acaattgaac tataaatatt acaaataaaa aaacggagga
    14161 gtgctttatg aaagcctata cttatgttaa accaggactt gcttcttttg ttgatgtaga
    14221 caaaccagtt attcgcaagc caacagacgc tattgtgcgt attgtaaaaa ccactatttg
    14281 tggaacagac ctccatatta tcaaagggga tgttcctact tgccaaagtg gtaccattct
    14341 tggccacgaa gggattggga ttgttgaaga agttggggaa ggagtttcca acttcaaaaa
    14401 aggtgacaag gtcttgattt cttgcgtctg tgcctgtggt aaatgctact actgtaaaaa
    14461 aggaatttat gcccactgtg aagacgaagg gggctggatt ttcggtcact tgattgatgg
    14521 tatgcaggct gaatatctac gtgtccctca tgcagataat actctttacc atactccaga
    14581 agacttgtca gatgaagctt tggttatgct gtcagacatt ctgcctactg gatatgaaat
    14641 tggtgtctta aaagggaaag tagaacctgg ttgcagcgta gccattattg gttcaggtcc
    14701 agttggattg gctgctcttt taacagccca attctattca ccagctaaat tgattatggt
    14761 agacctagac gataaccgct tggaaactgc cctatcattc ggtgcgactc ataaggttaa
    14821 ttcttcagac cctaaaaaag ccattaaaga aatttatgat ttgacagatg gtcgtggtgt
    14881 ggatgtcgct atcgaagctg tagggattcc tgaaacattt gatttctgtc aaaagattat
    14941 cggtgtagac ggaacggttg ccaactgtgg tgtgcatggt aaaccagttg aattcgattt
    15001 agataaactt tggattcgca acatcaatgt aacaactggt ttggtatcta caaatacgac
    15061 tccacaattg ttgaaagcac ttgaaagtca taagattgaa ccggaaaaat tggtaactca
    15121 ctatttcaaa ctcagtgaaa ttgaaaaagc ctacgaagtc ttcagtaagg cagcagacca
    15181 ccatgccatt aaggtcatta tcgaaaacga tatctcagaa gcctaagtag taaaaatatt
    15241 tttgtacata agcaaataga aattcagtca tccatcagat ggctggattt tttatcaaaa
    15301 aattaagaaa tgagcatatt tctttccttg tctggcggaa ttggttataa tatacggtac
    15361 aaaggaatga atgaatatgt atcgtgttat agaaatgtac ggagattttg aaccgtggtg
    15421 gttcttagaa ggttgggaag aagatattgt agcaagtaga aaatttgacc agtattatga
    15481 tgctctcaaa tactacaaaa cttgctggtt tagattggaa caagaatccc ctctttataa
    15541 aagtagaagc gacttgatga ccattttttg ggacccggaa gaccaacgct ggtgtgatga
    15601 atgtgatgag tatttacaac aataccattc tttggctctt ttgcaggatg agcaggttat
    15661 cccagacgaa aaactacgct caggctatga aaaacaaacc agtcaggaaa ggaatcgttc
    15721 ttgccgtatg aaatt
//
LOCUS       DAVBED010000050        15134 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBED010000050 DAVBED010000000
VERSION     DAVBED010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.050"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..210)
                     /locus_tag="VQ547_001644"
     CDS             complement(<1..210)
                     /locus_tag="VQ547_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543464.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMP"
     gene            296..997
                     /locus_tag="VQ547_001645"
     CDS             296..997
                     /locus_tag="VQ547_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HET2543465.1"
                     /translation="MYSGFTHYKYYRAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLL
                     QFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKL
                     YHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSK
                     FLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNI
                     VQIIELINNRAGEAA"
     gene            complement(1397..2743)
                     /locus_tag="VQ547_001646"
                     /pseudo
     CDS             complement(1397..2743)
                     /locus_tag="VQ547_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2805..2999
                     /locus_tag="VQ547_001647"
     CDS             2805..2999
                     /locus_tag="VQ547_001647"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543466.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2977..3177
                     /locus_tag="VQ547_001648"
     CDS             2977..3177
                     /locus_tag="VQ547_001648"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543467.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(3257..3702)
                     /locus_tag="VQ547_001649"
                     /pseudo
     CDS             complement(3257..3702)
                     /locus_tag="VQ547_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3710..3853
                     /locus_tag="VQ547_001650"
     CDS             3710..3853
                     /locus_tag="VQ547_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543468.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3946..4533
                     /locus_tag="VQ547_001651"
     CDS             3946..4533
                     /locus_tag="VQ547_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543469.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4932..5741
                     /locus_tag="VQ547_001652"
     CDS             4932..5741
                     /locus_tag="VQ547_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2543470.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5746..6447
                     /locus_tag="VQ547_001653"
     CDS             5746..6447
                     /locus_tag="VQ547_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2543471.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6472..7389
                     /locus_tag="VQ547_001654"
     CDS             6472..7389
                     /locus_tag="VQ547_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2543472.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7417..8958
                     /locus_tag="VQ547_001655"
     CDS             7417..8958
                     /locus_tag="VQ547_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2543473.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8977..9435
                     /locus_tag="VQ547_001656"
     CDS             8977..9435
                     /locus_tag="VQ547_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2543474.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9437..11659
                     /locus_tag="VQ547_001657"
     CDS             9437..11659
                     /locus_tag="VQ547_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2543475.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11699..12808
                     /locus_tag="VQ547_001658"
     CDS             11699..12808
                     /locus_tag="VQ547_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2543476.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12965..13855
                     /locus_tag="VQ547_001659"
     CDS             12965..13855
                     /locus_tag="VQ547_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2543477.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13880..14203
                     /locus_tag="VQ547_001660"
     CDS             13880..14203
                     /locus_tag="VQ547_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543478.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            14193..>15134
                     /locus_tag="VQ547_001661"
     CDS             14193..>15134
                     /locus_tag="VQ547_001661"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2543479.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         5050 a         2306 c         2996 g         4782 t
ORIGIN      
        1 aggcatacca gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt catatttctt
       61 caattggttt ccgcactcag ggcaagatgg ggcgtcgtag tccagtttgg cgatgatttc
      121 cttgtgtgaa tccctattga cgacatctat aatttggata tttgtgtctt tgatatcgag
      181 tagttttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttggtcgc
      241 ttttcattat agatcttatg ggactttttt tctacaataa aataggctcc ataatatcta
      301 tagtggattt acccactaca aatattatag agccgaaatt atcaggaaag tacaggagcc
      361 tgaattttgg aaagaagtta acttgtctga tttggaaaaa attcgtcttg ctattcgaga
      421 tttattacag tttttggata aaacagaccg taaaccctac tatgttaact ttgaagatcg
      481 tatactctcc actgttcacg agaccacagc atttttgcag gtcaacgatc ttcggtctta
      541 caatgaaaaa gttgagcatt atttgaaaac tcatctggat gaggagtcca tttctaagct
      601 ataccataat aaaaagttga catctgatga tatgcttgca cttgaaaaat tgctttggga
      661 aaaattaggt agtaaagcag actaccaaag tcattatgaa aataaggcaa ttccgagatt
      721 ggttcgtgag attattggct tagatagaga gtctgccaat cgtattttct ctaaattttt
      781 gtcggatgag aatcttaatg ccaggcagat ttcatttgta aaattgattg tagactacat
      841 tgtagaaaat ggttttttag agacgaaagt gttaacgcaa gagccgttta aatcttatgg
      901 ttctgttcaa ctactcttcc aacaccaact accagtactt cgtaatattg ttcaaatcat
      961 tgaacttatc aataatcgag ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg
     1021 agactcattt aaaattaaaa agagtagaaa tttatgctat atatgagaag ttttattagg
     1081 aagaatgtca tcgttttcct agaatacagt atcagttgtt aagtggttga taaatttcaa
     1141 agtagatact tgtaccacga tgtttgttga tcgagttatt aacaaaagag ctactttgat
     1201 tttaacccaa atcattcata cctctctcaa ctagatgtaa cttacaaaac ccctgacctc
     1261 atgagccact ttcttcctcc tcatgaggtc agttttactt tctgctgttc cagtatcgtt
     1321 tttcctcgct agatttcctc aaaagggcag actcctccct tggtgcgtca cacgattttt
     1381 tcatctcgac tgttctttaa tgcatcatta acgacgcttt tcttccaggt ggttcataag
     1441 gaacaggaag attcaggttg acttttctaa tcctagaata aagtgctgaa aacaattcgg
     1501 aataggcata gagactagac aatttgagga gctgcttgcg tcctgttcga acacattttc
     1561 ctaccacgtg aagaaaaaga tggcggaagc gtttgattgt taaagtttgg aagtcacctc
     1621 cagctagatg tttgagaaaa agatagagat tgtaggcgat acagctcatc atcatacgaa
     1681 cttcgttttt gattaaggtt gaactatccg ttttatcgcc aaaaaatccc tccttcatct
     1741 ccttgatgaa attctcggct tgaccacgtc cacgataaag ctgaaactgg tcttggcttg
     1801 ttccactcgt catatttgta acgagagaaa taacatcgta gaacaagttt ccttcttttc
     1861 gttcagagaa ctggcagaca cgacgcttgt gcgaccaaga tcctgcttga tagagagttt
     1921 ctgagtaggc ggagtggggc aagatggtta agtcctcatc ctgtgggcaa gggagggaaa
     1981 ggtctccaag acggctcaga acagtatttt tcttgagttt tatgagttag tattgccctg
     2041 ttttttcaat taaatcgtat aatttggggg tcgcaaagcc actatccatt cgaaagagaa
     2101 gttgattaaa ccgttctaaa acaggtgtga taaagctgtc tgcctcttca gaacaataac
     2161 gattaccagg acgaagctgg gcattgaaac aataacctgt cttcccctcg aaagcataaa
     2221 gaggatgata gccatgagca cgatagtggg cgttataagc aacaccttct tgcttgccat
     2281 aagttgtgaa atgggtagaa tcgatatcta caatgagttg gtttagctgg tgaaactgta
     2341 aaaagaattc gaccaattca aggttgaggc atcgcaaact atggactgtt tcctcgtcag
     2401 ttctggaaag aaaacgggat aaggttggct gtgaagcaag ctgccctcct tccaacaatt
     2461 ttggaaagta ggcatcagct gacaattctt tacaagcata gtccgttcca tagcctgtta
     2521 acagttgaaa gaggaactgg acaaggatat ctgaatccga ataacgacag tagcggcgtt
     2581 ggtcattcgt tactaaatac ttagaaatcc gctcttttag tttcaactgg gaaaaaagtt
     2641 cctgaaaaaa gataagacca ccatactggg ttaaatgacc tccatcgaaa gatagttggt
     2701 aaaaagactt gttttggaag tgatgatttg gtaaactgtt catgtgagtt tcctttcttt
     2761 ttgtgttttt ttctacactt ataccataaa ggggaaattc ttttttgtct agtaaaaaac
     2821 acccattggg tgaaaaaaga aaccatacag gatctaagct aaggcaagga ttctggatgg
     2881 tttttagatt aggggtgaat aattggggtt ttaaagaaat agaaaacaaa aagccgagca
     2941 agaattcaat tgcaggagaa aatgaaataa tactcaatga aaatcaaaga gcaaactagg
     3001 aaactagctg caggctgctc aaaacactgt tttgaggttg tagataagac tgacgaagtc
     3061 agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac
     3121 ggcaaggcga cgttgacgcg gattgaagag attttcgaag agtataaatc ttcctaggat
     3181 aaagcaaaga gcctgggaca aaatagttct cgaccacaaa aaagctagag atttccaatt
     3241 gtggaacttt agctttttaa ttttgagtcg ttctcttatt gtattttagg aggttattgg
     3301 ccataagtac caatcccatg tcaattctca cttgacgctt gcccctcaga ttacatctct
     3361 tgtaacccaa acaagccttt atctgcccaa agacaggtga cattctttag ctttcaagtt
     3421 ttgatagcct tcgttcatat acagtccctt ttgaggggct gattcaggtt cgtcggcgta
     3481 gtaaaccttg atttcttgtt taaagtctgt ctgtgttttc tgatgtttgg tatggtgaaa
     3541 acgataatac cagccatcag gatgtgtata gctatcctcc ttgtcattat agtaccaatt
     3601 cgctaagttt ctagctgact gtttatagcc tctcttctgt tccttatcaa acatggcata
     3661 tttaatcaga tggtttacct ccttttcatc taactaaagg agaagcaata tggctgaacg
     3721 attttgggag aacttgtcca ttattttggc tgacagaaat atcagctgga ttgagttaac
     3781 cagaaaaatg tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa
     3841 gattcgccac tagaagatgg aacaacgaat gcctcaaagt ccatgggtag aaaggattgt
     3901 gcaggtatta gatttagatt atgaagattt atttcggagg taattatgaa aagaataatt
     3961 ccagtttata tattccaaca agtaaatgtc ctattggtat ctctatactt attgaaattt
     4021 ctttgtagcg atgagttaac tatactacag attctctatg gagcgtcact catttctttt
     4081 ttatggatgt atggtcaacg aaaacaagtg atcaaggtta atatgaaaac taggatacaa
     4141 tggcttggta ttggattcgt tagcctactg attataagtc tatgttttag tctaatccat
     4201 gcgcaagaaa gcacgaatca agcaaactta attggacttc aacatcaaat tccttggttt
     4261 tcatttttat tgtttttaat caatgcgagt atggttgaag aatttctgta tagagaaatt
     4321 ttatggaact tggttagaaa attagatatt cgagttgctt tgacaagtgt tttatttgcc
     4381 ttagcacatc atccaggaac cattatagct tggtgtttgt atgtatcgct ggggatgttt
     4441 ttagggcttg tacgctacaa attggactta tggggcagta tggggctaca tttggtgtgg
     4501 aacctactag tttatagttt gctgcttttt taaaataagt gatctgattt atctcataaa
     4561 tcagtagttt ttataggatt atttttaatt cggaaacaaa aatgtattaa cagcataaaa
     4621 taaagaaact aggaacattt tttttatttt ttagaaataa aatgttgtat agaaattccg
     4681 aaagaaataa taaaatcaaa ataaaaatta ataaaatagg tatatttgaa catattgacg
     4741 tcgacaaatg ttcttgcaag acataaaata caaataaaaa gaataaaaaa tttttatatt
     4801 tttatatttg ttgttctgtt ataaaatgaa agaaattaga aactagtttc taaatcatga
     4861 aaaatattga aaaaaaaaaa ataagtgtta aaataaagaa tgtaaacgtt tacttcaata
     4921 aaggagctca tatgttactg caaaaagaac taattccaat gatagaagct aacttaccaa
     4981 atatggcata tgctgaaaaa gacattgcta aattcttctt aaaacagcaa cctctgaata
     5041 attattcatg taaggcattg tgcgaatgcc ttaatgtatc caaagcaaca ttgactcgat
     5101 ttgcgaaaaa atgtggtttt aaaggtttta gacaattcat tttcaaatac caagagatga
     5161 ttcgtgagaa agaaaagtta gcattgtata cagaggctac agaaaaagtt ttatccgact
     5221 atgaagaaat gttgagaaaa acttacacgg ttcttgatga agttcaactt gagcgtattg
     5281 ctgagatgat agaaactgct gagcgtgtat atctttatgg taaagtaagt tctgttcttg
     5341 ctttacaaga aatgaagatg agatttatgc gtctcggagt cattggtgaa gtattatcag
     5401 acgaggatat gattttgtgg aatagcttat tacttaatga aaattgcctt gtcattggag
     5461 catccgtttc aggtcaaact gatattgtac tagaaggtct tcaaaaagct gcggataaag
     5521 gcgctaaaac agttttaatg actacaagaa aatttgacga agaagattgt ttctttgatg
     5581 aactattgtt attagcttcg accaatcatc tctcgtatgg caatcgcata tcacctcagt
     5641 ttccaatact tttaattaca gactgcttat tctctcatta tctggaaagt ccagagagac
     5701 aatattatta caatcaaact attatccata aggaggaata ataaaatgag tcaaatttgg
     5761 actaaagaaa aatttataag tcaagtccat ggtggagtca ttgtttcttg tcaagcttta
     5821 cccggtgaac ccctttataa tgaagaattt agcttgatgc cttttatggc taaagcagct
     5881 ttagaggcag gagcagtggg cattcgcgca aattctgtgc gtgatattaa agcaattcag
     5941 aaagtagtag atttaccaat aattggaatt atcaaaagag attatccacc tcaagaacca
     6001 tatattactg ctacgatgaa agaagtagat gaacttgtag aatgcggaac aacagtcatt
     6061 gcatttgatg caactttaag accaagatat gatggcttag ttatcaatga atttatcaaa
     6121 aaaataaaag aaaaatatcc taatcaattg ttgatggcgg atgtaagtaa ttttgatgaa
     6181 ggtctctatg catttaaatc aggcgttgat tttgttggta caacattatc agggtacaca
     6241 agtacaagtg tacaatcaga tgagcctgat tttgaactaa tgaaaaaatt ggctgatttt
     6301 aatattccgg taattgccga aggaaaaatt cattatccag aacaattaaa aaaagcttat
     6361 agtttaggtg ttaccagtgt tgtcattggt ggagcgatta cacgtccaaa agaaattgct
     6421 cagcgattta ttaatgtcat caaataaaaa acaatataaa ggagaaatct gatgaaagat
     6481 ttaactaaat acaaaggcgt tattcctgca ttttatgctt gctatgatga aaatggtgaa
     6541 attagccaag aacgtgtaaa atctctggtg caatatttca ttgacaaagg tgtaaaaggt
     6601 atctatgtaa atggttcttc aggtgaatgt atttaccaaa gtgtagaaga tcgtaaacaa
     6661 attattgaag ctgttatgga agttgctaaa ggtaaattaa cagttatcaa ccatgttgca
     6721 tgtaataaca cgaaagatag tattgaattg gcaaaacatt cagaaagtgt tggagtcgat
     6781 gctattgctg ctatcccacc tatttacttc aaattgccag aatattcaat tgcagcatat
     6841 tggaatgcaa tgagtgaagc tgcgccaaat acagatttta tcatttataa tattccacaa
     6901 ttggcagggg ttgcgttgac tggtagtttg tatgcaacaa tgcgtcaaaa tcctcgtgtg
     6961 attggagtta aaaattcttc tatgcctgta caagatattc aaatgtttgt agctgcaggt
     7021 ggagaagatt acattgtatt caatggtcca gatgaacaat atcttggtgg tcgcttgatg
     7081 ggagcagaag ctggtattgg tggtacttat ggcgttatgc cagatttgtt cttgaaattg
     7141 gaaagtttga ttcaagaacg agatttagat actgctaaaa aacttcaata tgctatcaat
     7201 gaagttatct ataagatgat atcaggtaag gcaaatatgt atgctgtagc aaaagaggtt
     7261 ttgcgtctaa atgaaaaact tgatttaggt tctgttcgtc aacccttaga agcattggca
     7321 gaaggtgact tggaagttgc aaaacaagca gcagaactta ttcaacaagc acgaaaagaa
     7381 tttttataat aaataaaatc aatatggaga tatgttatgg gcacaacagg atttacaata
     7441 attgacttaa ttatcttgat tgtttattta cttgcggtgt tggttgcagg tatctatttc
     7501 tctaaaaaag agatgaaagg aaaagagttc ttcaaaggag atggttcggt tccttggtat
     7561 gttacttcgg tatccatttt tgccacaatg ctcagtccga tttccttctt gggactcgct
     7621 ggtaactctt atgcaggtag ctggatttta tggtttgctc aattagggat ggtagtagct
     7681 attccactga caattcgttt tatcttacct atctttgcac ggatagacat cgatacggca
     7741 tatgattact tggataaacg ttttaattct aaagcacttc gtattatttc agcactcttg
     7801 tttattattt atcaattggg acgtatgtct atcattatgt acctcccatc agctggttta
     7861 tcagtattga caggaattga catcaatatt ttgattattt tgatgggtgc agttgcaatt
     7921 gtttattctt acactggtgg tctaaaatcc gtattatgga cagactttat tcaaggtgtg
     7981 attctgatta gtggtgtcgt tttagcttta tttgtactga tggctaatat taaaggtggc
     8041 tttggtgcag tagcagaaac attagcaaac gggaaattcc ttgctgcaaa tgaaaaactt
     8101 ttcgatccta acttgctttc aaactccatc tttttaattg tgatgggttc aggctttaca
     8161 atcttgtctt cctatgcttc atctcaagat ttggttcaac gttttactac aacacaaaat
     8221 attaagaaac ttaataagat gttgttcaca aacggtgtct tgtcacttgc aactgcaaca
     8281 gtcttttact tgattggtac aggcttgtac gtattctatc aagtacaaaa tgcaggtagt
     8341 gcagctagca atatccctca agaccaaatc tttatgtact ttattgcata ccagttacca
     8401 gtaggtatca caggtttgat tttggcagcg atttatgcag catctcaatc aactatttca
     8461 acaggtttga actctgttgc aacttcatgg acattggata ttcaagatgt catttctaaa
     8521 aatatgtcag acgatcgtcg tacgaaaatt gcacaattcg tatctctagc agtaggttta
     8581 ttctcaattg gtgtttccat tgtcatggct cactcagata ttaaatctgc atacgaatgg
     8641 ttcaatagct tcatgggact tgtacttggt ctacttggtg gtgtatttat tcttggattt
     8701 gtttctaaaa aagcaaataa acaaggtgct tatgcagcgc tgattgtatc aactatcgtc
     8761 atggtattta ttaaatactt ccttcctcca acagctgtga gctactgggc atattcattg
     8821 atttcaatct ctgtatcagt agtttcaggt tatattgtat ctgttcttac tggaaataaa
     8881 gtatctgcac ctaaatatac aacgattcat gatattccag aaattaaagc ggattcaagt
     8941 tgggaagttc gtcactaata gaaaagagaa aataatatga ttatttctga acaatctgat
     9001 tttagacgat atgcttctat caataaacat ttttcaaaag tctgtgattt tttagaaaat
     9061 acaaatttga cagatttagt tgatggaaaa gttgatattg acggggaaaa tgtttttgca
     9121 aattgtatga tctatctagc tgatggagtc ccaggagata tttttgaaac tcataagaaa
     9181 tatttagata ttcatattgt tgttgaaaat actgaaaaaa tggcagtaac ttccccagtt
     9241 cgtgcccagt cacgtgtacc ttttagcgaa gaaaaggata ttgcttttta cgatagcaaa
     9301 gactatcaaa ttgttgaatt gcttccaggg aatatgttgg tgacttttga agaagatctt
     9361 caccaaccaa agattcattg caatgatgag cctgttaaaa aacttgttat taaagtttta
     9421 aacgaggaaa aataaaatga aaaaaaatat taaacaatac gtaaccttag gtactgcagt
     9481 ggtattatca gcatttgttg ctaactcagt tgcagctcag gagactgaaa cttctgaagt
     9541 atcaacacca gagttggtgc aacctgttgc accaacgact ccgatttcgg aagtacaacc
     9601 taaatcgggt aactcttcgg aagttactgt acaacctaga acagtcgaaa ctactgttaa
     9661 ggatccatct tctgcaacgg aagaaactcc tgtcttagaa aaaaataatg ttactttaac
     9721 agggggcgga gaaaatgtta ctaatgagtt aaaggataaa tttactagcg gtgactttac
     9781 tgtagtgatt aagtacaatc agtctagtga gaaaggctta caagctctgt ttggaatatc
     9841 taattctaaa cccggtcaac aaaatagtta tgtagatgtg ttccttagag acaatggtga
     9901 attgggaatg gaagcgcgtg atacttcttc caataaaaat cacctagtat ccagacctgc
     9961 ttcagtttgg ggtaagtaca aacaagaagc tgtgactaac actgttgcag tagtagcaga
    10021 ttcagtcaaa aaaacatatt ctttatatgc aaatggtaca aaagtagtag aaaagaaagt
    10081 ggataacttc ttaaacatca aggatattaa aggtattgat tactatatgc ttgggggagt
    10141 gaaacgtgca ggaaaaacgg cgtttggttt taacggaaca ctagaaaata tcaaattctt
    10201 taatagtgca ttggatgaag aaactgttaa aaagatgaca acaaacgctg ttactggaca
    10261 tttaatttat acggctaatg atacaacagg ttctaactat ttccgtattc cagttctgta
    10321 tacttttagc aatggtcggg tattttcaag cattgacgct cgttacggcg gaactcatga
    10381 ttttttgaat aaaattaata ttgctacaag ttatagtgat gataatggta agacatggac
    10441 taaaccaaaa ttaacattgg cattcgatga ttttgcgcca gtaccattag aatggcctcg
    10501 tgatgttggt ggacgtgact tacaaatcag cggtggtgca acctatattg actctgttat
    10561 tgttgaaaaa aataacaaac aagtactcat gtttgcggat gtgatgcctg ctggagtaag
    10621 ttttagagaa gctactagaa aagattcagg ttataaacaa attgatggta attattacct
    10681 taaattaaag aaacaaggtg atactgatta caattatact attcgtgaga atggtactgt
    10741 atacgacgat cgtaccaaca gaccaactga attttcagta gataaaaatt tcggtattaa
    10801 acaaaatggt aattatttga cagtagagca atattcggtt tcatttaaaa ataataaaaa
    10861 gactgaatat cgtaatggga ctcacgtcca tatgaatatc ttctacaaag atgcattgtt
    10921 caaagtagtg ccaacgaact atattgcata tatttctagc aatgatcatg gcgaatcttg
    10981 gtctgcacca actttattac ctcctataat gggacttaat cggaatgcgc cttatttggg
    11041 tcctggacgt ggaatcattg aaagctcaac tggacgtatt cttattccgt cttacactgg
    11101 taaagagtct gcattcattt atagtgacga taatggagca tcttggaaag ttaaagttgt
    11161 gccacttcct tctagttggt cagcagaagc acaatttgta gaattgagtc caggagtaat
    11221 tcaagcatac atgcgtacaa ataatggtaa aattgcatat ttaacaagta cagacgcagg
    11281 tactacttgg agtgcaccgg aatatttgaa atttgtttca aatccaagtt atggaacaca
    11341 attatcaatc atcaattata gtcaactgat tgatggtaaa aaggctgtca ttttaagtac
    11401 tccaaactcc acaaatggtc gtaaacacgg acaaatttgg attggtctaa ttaatgatga
    11461 taatacaatt gattggcgtt atcatcacga cgttgattat agtaactatg gatactcata
    11521 ttcaacattg acagagttac caaatcatga aattggattg atgtttgaaa aatttgattc
    11581 atggtctcgt aatgaacttc atatgaaaaa tgttgtacca tatataacat ttaagattga
    11641 agatctgaaa aagaattaaa gctgaaattt gaaaatatat aaaaagagga taaaaattat
    11701 ggtaaattac ggtattgttg gagctggata ttttggagct gatttagctc gctcaatgaa
    11761 caaaattgaa gatgcaaaag tggttgcggt atttgaccca aatcatggag aagaagttgc
    11821 tcaagagttg ggatcagatg tttgtgcaag tttagatgaa cttgtagcac gtgaagatat
    11881 tgattgtgtg atcgtagctt cacctagcta ccttcaccgt gaaccagttg tgaaagctgc
    11941 tcaacatggc aaacacgtat tttgtgaaaa gccaattgca ttgtcttatg aagattgtaa
    12001 agccatggtt gacgcatgta aagaaaataa tgttatcttt atggctggtc acatcatgaa
    12061 cttctttaac ggtgtacacc atgctaaaga attgattact caaggtaaaa tcggtaaagt
    12121 tctttattgc catgccgctc gtacaggttg ggaagaacaa caaccaactg tatcatggaa
    12181 gaaacttcgt tctcaatctg gaggacattt gtaccatcat attcatgaat tagattgcat
    12241 tcagtttatc atgggaggac ttcctgaaaa agcgacaatg gtaggaggca atgtatatca
    12301 taaaggtgaa aactttggtg atgaagatga tatgctcatt gtaaacttag aatactctga
    12361 tgatcgttat gctgttttgg aatatggtaa tgctttccgt tggggtgaac actacgtctt
    12421 gattcaagga actgaaggag ctatcaaact tgatttgttc aatactggag gtactcttcg
    12481 tgttaaaggt gaaggagaat cacacttctt agttcatgaa actcaagagg aagatgatga
    12541 ccgtacagct atctataccg gtcgtggtat ggatggagca attgcgtacg gtaaaccagg
    12601 agtacgttgc ccattatggt tgcaaacatg tattgataaa gaaatggaat atctacatga
    12661 catcattaaa ggtggagaaa ttacagaaga atatgaaaaa cttctcaatg gtgtagctgc
    12721 tttagaatca atcgctaccg ctgatgcatg tactttatca gttaaagaag atcgaaaagt
    12781 aagtctttca gaaatcacaa atgcttaact tttgtaaaac agaatagtaa attcttatca
    12841 ttatataatt tctaaagttc tgtgatacaa ctcattgaat aaagaaatag agatgggact
    12901 gggataatgc ccagtcccat tttttatcaa aaagtaatga gatcaaaaat gtgggagtga
    12961 tgaaatgaag attataggga tcgatattgg cggaacaaca attaaagcag atttatacaa
    13021 tgagtttgga acgagtttaa atcagttcaa agagatagaa acaattattg actatgattt
    13081 gggaacgaac cagatattaa atcaggtctg tgatttaatt ggtgagtata ttttaaatca
    13141 ttcaattgat ggtgttggga tttccactgc tggagttgtt aatgctaata caggagagat
    13201 catctataca ggctatacaa taccagggta tatcggagta aactttactt tcgaaataga
    13261 aaaacgtttt gggttgtcta cttttgttga aaatgatgtt aattgtgctg cattaggtga
    13321 attgtggaag ggacaagcca aagataagaa aaatgtagta atggttacta ttggaacagg
    13381 tataggaggc agtattattg tcaatggaca aattgttaac ggatttaact atactgctgg
    13441 tgaagtaggc tatattcctg taggtaattc ggattggcaa agcaaagcct caacaaccgc
    13501 attgattcat ttatatcaaa agaaaagctt gaaaactaat caaactgggc gtactttctt
    13561 tactgattta agagctggag ataaagtcgc taaagaaact tttgaaattt ttgtagaaaa
    13621 tctaacaaaa ggtttattaa cgattactta tctacttaat ccagaaattc tcatattagg
    13681 aggtgggatc ctggctaaaa aggatatttt gttacctgaa attcaaagtt ctttagctaa
    13741 aaatgcaatg gataataggt ttttgcctaa aaatcttgtg gcagctacat taggaaatga
    13801 agctggtcgt ataggagctg taaaaaattt cttagataga atttctaata aatagtatga
    13861 aagataagga ggtgtcacaa tgactaactc tgtattttcg acaatgcaag atattgagaa
    13921 tgttgcaacc gatattataa aatcatatga taatgagatt tatacttata aagctgtttc
    13981 ccaagaagaa ttggaaaaac tagaaaaaag ttatgatgaa aaaagtcacg aagaattagt
    14041 ttcaatagaa agcaatttag aaatgaaaca acagaacctt attgatgagg ttaataaaac
    14101 aatcaaggaa aattatgaaa agattcagta tatttcatca agtaggagag gagaatttgt
    14161 agaaaaaatt attggtaggg tggtagaaaa atatggctat tagtcagatg aaaagaattt
    14221 ctctactatt ttctaaaagt agtcttgatg atgttttaaa aactattcaa gaactagagt
    14281 cagtgcagtt ccgtgattta aaggttcagg ataactggtc agaagctcta gaaaaagatg
    14341 aggttgtatt tccaactatt caaatttctc atacttctaa ttccaatcat ggggttattg
    14401 aaggaaatga tgccttgatt tatttgatga atcaacaaca atatttagaa gcaactgtag
    14461 agaaattaca agaataccta ccgaaagaaa acacgtttaa attattacag caacctccga
    14521 taacgacctc ttatgaagaa ttagaaaaat ttggtaaagc taatgttgct gagggtgttc
    14581 ttaaaaaagt gaatcgtcaa ataaacagag ttcatgaatt agaaagacac attcaaagta
    14641 ataatgagga aatagagaga ttaataaaat gggaaaaatt agaaattatt cctgcgcatt
    14701 tagaacaatt ttttttctgt aaaggaaaag tcggaacaat tccaaggact gtagataatc
    14761 gcttatacaa tagtttttta gaaaacaata ttgaagttca agaaatattt tctaatgata
    14821 gagagtacgg tgttgttgtt ttctatcagt ccagttgctc tattgatttt gatgaatact
    14881 tatttgaacc atttgattat tctagaaagg aattaccgaa gcagcgagta gtagatttgg
    14941 atcaagaaaa catgcagtta ataactgaaa aagagaatat tatcgcatcg ttgcaagatt
    15001 caaagaataa tttgatagat ttacaatggc aaattgacta tattttatct atctatgctc
    15061 gtcaaatctc taagaataac cttttgagca ctccgcatct agttgcacta gaaggatgga
    15121 tagaagaaac tcgt
//
LOCUS       DAVBED010000051        14254 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBED010000051 DAVBED010000000
VERSION     DAVBED010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.051"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQ547_001662"
     CDS             3..350
                     /locus_tag="VQ547_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543480.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQ547_001663"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQ547_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2543481.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQ547_001664"
     CDS             2173..2886
                     /locus_tag="VQ547_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2543482.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQ547_001665"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQ547_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2543483.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQ547_001666"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQ547_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQ547_001667"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQ547_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQ547_001668"
     CDS             complement(5113..5733)
                     /locus_tag="VQ547_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2543484.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQ547_001669"
     CDS             complement(5733..6215)
                     /locus_tag="VQ547_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2543485.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQ547_001670"
     CDS             complement(6215..7057)
                     /locus_tag="VQ547_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2543486.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQ547_001671"
     CDS             complement(7152..7952)
                     /locus_tag="VQ547_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2543487.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQ547_001672"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQ547_001672"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2543488.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQ547_001673"
     CDS             9485..10030
                     /locus_tag="VQ547_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2543489.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQ547_001674"
     CDS             10042..10356
                     /locus_tag="VQ547_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2543490.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQ547_001675"
     CDS             10373..11065
                     /locus_tag="VQ547_001675"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2543491.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQ547_001676"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQ547_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2543492.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQ547_001677"
     CDS             11731..12321
                     /locus_tag="VQ547_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2543493.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQ547_001678"
     CDS             12330..14093
                     /locus_tag="VQ547_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2543494.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVBED010000052        14236 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBED010000052 DAVBED010000000
VERSION     DAVBED010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.052"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(159..1085)
                     /locus_tag="VQ547_001679"
     CDS             complement(159..1085)
                     /locus_tag="VQ547_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543495.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ547_001680"
     CDS             complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ547_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2543496.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1788..2883)
                     /gene="prfB"
                     /locus_tag="VQ547_001681"
     CDS             complement(join(1788..2810,2812..2883))
                     /gene="prfB"
                     /locus_tag="VQ547_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2543497.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2991..3647)
                     /locus_tag="VQ547_001682"
     CDS             complement(2991..3647)
                     /locus_tag="VQ547_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2543498.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4112..4822)
                     /locus_tag="VQ547_001683"
     CDS             complement(4112..4822)
                     /locus_tag="VQ547_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543499.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4822..5586)
                     /locus_tag="VQ547_001684"
     CDS             complement(4822..5586)
                     /locus_tag="VQ547_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543500.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5586..6542)
                     /locus_tag="VQ547_001685"
     CDS             complement(5586..6542)
                     /locus_tag="VQ547_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2543501.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6546..7415)
                     /locus_tag="VQ547_001686"
     CDS             complement(6546..7415)
                     /locus_tag="VQ547_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2543502.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7683..8843)
                     /locus_tag="VQ547_001687"
     CDS             complement(7683..8843)
                     /locus_tag="VQ547_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2543503.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8944..9192)
                     /locus_tag="VQ547_001688"
     CDS             complement(8944..9192)
                     /locus_tag="VQ547_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2543504.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ547_001689"
     CDS             complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ547_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2543505.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ547_001690"
     CDS             complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ547_001690"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2543506.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10753..11220)
                     /locus_tag="VQ547_001691"
     CDS             complement(10753..11220)
                     /locus_tag="VQ547_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2543507.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11239..11796)
                     /locus_tag="VQ547_001692"
     CDS             complement(11239..11796)
                     /locus_tag="VQ547_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2543508.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11921..12766
                     /locus_tag="VQ547_001693"
     CDS             11921..12766
                     /locus_tag="VQ547_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2543509.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            12825..13997
                     /locus_tag="VQ547_001694"
     CDS             12825..13997
                     /locus_tag="VQ547_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2543510.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            14048..>14236
                     /locus_tag="VQ547_001695"
     CDS             14048..>14236
                     /locus_tag="VQ547_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2543511.1"
                     /translation="MEHIILLRGVTPNGKNAIPKMSYLVDILTEADFQQVRTYIQSGN
                     IILESNLALEEIREQVHTL"
BASE COUNT         4231 a         3092 c         2607 g         4306 t
ORIGIN      
        1 aatttctagt gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga
       61 cttctttgga agctcttttc ttctacgcat ctcttttcaa aaactcttgt agcaaaaaag
      121 gagattttac aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc
      181 atggatattc ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc
      241 atcaacggac taaataaatc tggactaatc atggatagat tttgccctac caacgatttg
      301 ttgacagatt ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct
      361 cccaataaac cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta
      421 gctccaacca agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg
      481 gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa
      541 acacggataa atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc
      601 tcagagacac cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg
      661 tttgcctcta caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag
      721 ttatctccca ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca
      781 cttttaaccg tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta
      841 acagtttgac cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa
      901 actactacac ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca
      961 gatgcaaata ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc
     1021 atccaaccat ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta
     1081 atcatcgtat ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc
     1141 aatgacacgg tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt
     1201 tgtcccttgt aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc
     1261 cagatttcct gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc
     1321 aatcgcaatt cgctgctgct ccccacctga gagttcattt gggaaagaac gaaccttatg
     1381 cttcaatcca accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc
     1441 cccgattact tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacaattt
     1501 ataatcttgg aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat
     1561 cttaaccaga ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata
     1621 cagagaacga ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc
     1681 ccccggttga acgctgaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt
     1741 aacgacatct ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc
     1801 cacttgagat aagcatctat aaaaccatct aggtccccat ccataacctt atctacctga
     1861 gcaacctcaa agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa
     1921 cggatttggc ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca
     1981 gccttcttat cttgctccat ttgatagagc ttagcctgca acatcttcat ggcacgatct
     2041 ctatttccat actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg
     2101 gttaaacgta cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg
     2161 aaggtatcca tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct
     2221 ggcatcactt ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag
     2281 attcgcacta agcggtgaac acccatttct gacttgagga gaccataggc attaggccct
     2341 tcaaatgata aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact
     2401 tccactttaa agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc
     2461 cagtcctgcg cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg
     2521 tcataaggtt ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg
     2581 gctaactgcg ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa
     2641 atttcgactt catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat
     2701 tcattcaatt cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct
     2761 gtcatcttgt tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc
     2821 cctgaaagaa gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc
     2881 cataaatact ccttttttac attatttcat tatagcatat tttatcattt ctttccatct
     2941 tttgctctaa tccccttttc atgaaaaaag aagcctttgg acttcccttc ttacaagact
     3001 tttgctgaag tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctctc
     3061 aaggctggta aatcaattga ttcatcgatt tgcacttcga taatcacctt accatcctta
     3121 cgcggaatat tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt
     3181 tttccaagaa caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca
     3241 taacctgcaa tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact
     3301 tgatggttat ctacgacagg gagaatacca atcttatttt tcaacatcag ataagttgca
     3361 tcttctagac tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact
     3421 tttgtcttat tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga
     3481 cttgcttgtg caatggttcc ctcagtcacc aaaccaacca attgatcatt ttcgataaca
     3541 ggcagacggt gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct
     3601 ggactaatat aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt
     3661 ttctattctt atccctatta tacaatcttt ttgcaaatct atcaaacgct tacatttctt
     3721 tttcaaaatt tagaaaagta tgaataagct agcaaaaaga gctctaaaat cgagctctgt
     3781 gaatgaaggt aagaaacttt tcattcgatt ttttcaatta ttagaaatta agctttcaat
     3841 gtagatgcag atttgtttgc aatctcaatc taccggctaa aacaatcctc tggatttgat
     3901 gattgcttcg caatcttcat ccaccgacta aaaagggccc ccggactata ttgatgatta
     3961 cttcgtaatc tttatctgcc ggctaaaaca atcctctgga tttgatgatt gcttcgcaat
     4021 ctcaatctac cgactaaaaa gggcccccgg actatattga tgattacttc gtaatcttca
     4081 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
     4141 cttctgatga agcgagttct tttcctgttc ctgataggac gatttttcct gtttccaata
     4201 catatcctcg gtcagagatt gcaagtgctt tattggcatt ttgttcaatc aagaggacgg
     4261 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggatg aagattgggg
     4321 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
     4381 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
     4441 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt agcttgattt tcttcacgat
     4501 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
     4561 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggtatttttt
     4621 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
     4681 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
     4741 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
     4801 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
     4861 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
     4921 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
     4981 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
     5041 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
     5101 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
     5161 atctaaatca aagattttca acaattccaa agctttagcc tttaattctt tttcactctt
     5221 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
     5281 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
     5341 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
     5401 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
     5461 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
     5521 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
     5581 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
     5641 cacgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc taaagcgtaa
     5701 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
     5761 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
     5821 ttgattgagt taatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
     5881 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
     5941 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
     6001 cggccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
     6061 taaaccattt gccaagttgt aaagttagga atccctaaga tacctgccgc accatttgta
     6121 agacttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
     6181 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
     6241 gaaagcaaag cccctacaag catagctcca aagaaggcac cgtaggttgg taatttagaa
     6301 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
     6361 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
     6421 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
     6481 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
     6541 atcgtttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
     6601 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggcagtc
     6661 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
     6721 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
     6781 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
     6841 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
     6901 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
     6961 aacaaaatca tcaaaatcaa ggaaatggcc aaaatcatta actgcacatt tgttaagcta
     7021 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
     7081 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
     7141 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
     7201 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
     7261 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
     7321 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
     7381 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
     7441 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
     7501 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
     7561 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
     7621 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
     7681 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
     7741 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
     7801 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
     7861 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
     7921 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
     7981 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
     8041 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
     8101 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
     8161 ttccctttca tgtttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
     8221 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tagcaatccc tttagcatag
     8281 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
     8341 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
     8401 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
     8461 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
     8521 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
     8581 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
     8641 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
     8701 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
     8761 gctccagact tcacttctac acaggctgca agaagtgcta cacttgcaag cgccacaaac
     8821 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
     8881 atataccgaa ttatcagaaa attgtcaatg ttttccttga actttttcga tgataacgtt
     8941 ttcctatcga taaagattgc ccacaaaggg tgtttccaac tcttggatat gacaaaccct
     9001 aactttttta ataaattttt ccttgctcaa gcgtccgacc aattgctcca cttcttgagt
     9061 tggaacatag agttgtaagt aacgatgttt cttggaatga taggtaatat ctccataatc
     9121 ctgcagtttt ttggcatcac gattatagta aagatagata atcaagccag agcgattgac
     9181 tttttcaaac atgataaatc ctctttctaa gaaatctctc cctattatac caaaaaaagc
     9241 aaacccagtc gagtttgcct tctatcatca ttagttcaat gaattgttgg ccataatttc
     9301 atcaataaag ccatattcaa gtgtttcctg ggcgctcatc cagttatcac gttctgcatc
     9361 tgcatggact ttttccattg actgacctga attttcagcc aagatttttt ccaaggtatt
     9421 acgagttttg agcaagtgtt ctgcagcgat agccatatca gtttgttggg taccaccacc
     9481 tgtaccgccc attggttggt gaatcatgta ttcagcattt ggaagcatga aacgtttgcc
     9541 ttttgctcca cttgatgcga tgactgttcc catagatgca gccattccca taacaatggt
     9601 ttggacatct gccttgataa agttcatggt atctacgatt gccaaaccag ctgaaacaga
     9661 accacctggt gtattgacat aaaggtaaat atcttttgta ctatcttggg catccaagaa
     9721 aagcagttgg gcaataacag agttagccat attgtcttca accggacctg tcagcataat
     9781 gatgcggtct ttgagaagac gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg
     9841 ttcaataact acaggaatca ttcatttctc cttttgagtt ttaattttgt tggtcaaatg
     9901 actgaagata agactattat aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt
     9961 cattagacag aaacaaaaac ccaacctcct ttcgtgactg gaaatacttt tccaagtcat
    10021 tcttcttttc gatcttattt tgtaccgaac aagcggtctc cagcatctcc aagacctgga
    10081 acgatataac cgtgttcgtt caaacgttca tccaaggctg ctgtaaagat ttctacatct
    10141 ggatgagctt cttgaagggc ttttacaccc tctggagcag atacaaggca gacaaatttg
    10201 atatttgatg cgccacgttt tttaagagaa tcaacagcca agattgctga gccacctgtt
    10261 gccaacattg ggtctactac aaaaatttga cgttggtcaa tgtcctcagg caatttcacc
    10321 aagtattcaa ctggttgaaa tgtttcttca tcacggtaca taccgatgtg gccaacttta
    10381 gcagctggaa ccaagctcaa gagaccatca accatcccga tacctgcacg caagattggg
    10441 acgatggcca atttcttacc tgccaattgt ttttgaactg tttttgtaat tggtgtttcg
    10501 atttccacat cttctagtgg aagatcacga agtacttcat accccatcaa cattgcaatc
    10561 tcatctacta gctcacgaaa agcttttgta gaagtatctg tacgacgcaa gattgacaat
    10621 ttgtgttgaa tcagtgggtg attaataact tcaatttttc ccatttttgg aattccttct
    10681 ttcaatttat tcttcttatt ataccaaaaa acgggttaaa aatctttcta aaccatttat
    10741 ttttgataat ttttacatta gatcagcctc tttaagagct gtctgtactg tctcaagtgg
    10801 taaatgggtc aattctgtcc ctttttcttg ataaaggtat tgggcgtagt cgtccattcg
    10861 gtactggttg atataaacca cacgcttgca gccgacctga agcaattgtt ttgtacagtt
    10921 gagacaagga aaatgggtta cataggctgt aaagcctttg ggaacaccac gctcagcacc
    10981 ttgaaggata gcattgacct cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa
    11041 acattcgtga tcaatacaat gctcagtccc tgacaccgaa ccattgtaac cagtggaaat
    11101 aaccttatta tcttttacca gaatcgcgcc cactttagca cgtttacaag tggaacgatt
    11161 cgcaattagt agagcttggg ctgcaaaata ctcatcccag gccagtcttt tttcagtcat
    11221 ctcttttctc ctttttctct attttttaaa aaatggtaaa cctaaatctg caatcttttc
    11281 agctggtacc ttcatgccat ccttgatcca ttttagaagg acagagacga tggctgagct
    11341 ccagaaggaa tgaagataag agctgacacc ttttgatttc ccatggtatt tttctagaaa
    11401 ttcctgcatg gcttggacaa agattttttc cagatggtaa tccaaggcca attgaattac
    11461 tctagcttcc tttctggcct cccggaaaag gtgaacccaa accaaataaa ggtctgtctt
    11521 taaatcgtaa tgatgcagct gttccataat attgtggaca gttcgtttaa agacgctctc
    11581 taaaatttcc tctttggagt cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg
    11641 tttgaccaat tcagaaatac taatcttggt cagttccttt ttttccaaga gttgcaagag
    11701 ggctgtttca atggcttctc tggttaataa attggattct tggtttgatt ttctgagatt
    11761 ttcaagagac ttttcagaga ttctacgttc agacataaca ttttctttct acttgtcaca
    11821 acagacggat gatgcttttg tttcaagggt tttcatgata taattgtaaa aaaagacaga
    11881 acctttgtca atgtataact gacaaagatg gagaatttct atgacttgga agattattgc
    11941 tgactctggt tgtgattatc gtcaactgcc aacaccagct attaacacaa cctttgtaag
    12001 tgtcccctta accattcaag tagctgatca ggtctttgtt gatgacgcca gtctcgatat
    12061 tgaccaaatg atggaaacca tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag
    12121 cccagatgac tatttgcgag catttgaagg tgccaaaaac attttcctag taaccatcac
    12181 aggtaccctt tctggcagtc acaatagtgc tcaactagca aagaatattt atctggaaga
    12241 ccatcctgac actaagattc atgtgattga tagtttatct gctggtggtg aagttgacct
    12301 actcgtagaa aaattgaatg acttgattga ccagggcttg tcttttgaag aagtggttga
    12361 agctatcacc gcctatcaag aaaaaactaa gttgctcttt gtcctagcca aagtcgataa
    12421 cttggtgaag aacggccgtt tgagcaagct tatcggtacg gtcgttggcc ttctcaacat
    12481 tcgtatggtc ggaaaagcta gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg
    12541 atcaaagaaa tcagttcaag ctgcctatga tgagttagta aaagctggat atgctggtgg
    12601 ccgtattgtc atggcccaac gcaataacga aaaatgttgt caacagctct cagagcgaat
    12661 ccgtgaaacc ttcccacaag cggatattaa aattctacca acctctggtc tctgcagttt
    12721 ctatgcagaa gatggcggtt tgctgatggg ctatgaaatt gattaattgt attcttgaca
    12781 agaggtgacc atcatctctt gtttttttgt ggtacaatag agctatgaaa cattttgata
    12841 ctattgtcat cggtggggga cctgctggta tgatggctac gatttccagt agcttttatg
    12901 gacagaaaac cctcctcatc gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg
    12961 gtgggggacg ttgcaatgtg accaacaatg gtagcttaga caacctgcta gctggaattc
    13021 ctggaaacgg acgctttctt tacagtgttt tctcccagtt cgataatcat gacatcatca
    13081 acttttttac agaaaatggt gttaaactta aggtcgaaga ccacggacgc gtctttccag
    13141 ccagtgacaa gtctcggact attatcgaag ctttggaaaa gaaaatcacc gaactaggtg
    13201 gtcaagttgc tactcaaata gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc
    13261 ttaagtcagc ggatcaaacc ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt
    13321 cttatccttc gactggttcg actggttttg gtcacgagat tgctcgccat tttaagcata
    13381 ccatcaccga tcttgaggct gctgaaagtc ctttattaac agattttcca cataaagcct
    13441 tacaagggat ttctttggac gatgtgaccc taagttatgg taagcatgtc atcactcatg
    13501 atttactctt tacccacttt ggtttgtcag gtcctgctgc cctacgcatg tctagctttg
    13561 tcaaaggtgg ggaggttctc tcactcgatg ttttgcctca actttctgag aaggacttgg
    13621 ttacatttct agaagaaaat cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac
    13681 cagaacgctt ggccgaattt tttgtacaag gatatcctga aaaagtcaaa caactgactg
    13741 aaaaggaacg agaacaactt gtccagtcca ttaaagaact taaaattcct gtaactggaa
    13801 aaatgtccct tgcaaagtcc tttgttacca agggtggagt cagtctcaag gaaatcaatc
    13861 ctaaaaccct tgaaagtaag ctggtacctg gcctccactt tgcaggcgaa gttatggata
    13921 tcaatgccca cacaggtggc tttaacatca cttctgccct ctgtaccggc tgggtggcgg
    13981 gatcaaatcc aatctaaata tacattacta aatggaacaa tcccccaaaa aaaagaaagg
    14041 aactactttg gaacatatta tcttgctaag gggagtcact cctaatggaa aaaatgctat
    14101 ccctaaaatg tcttatctag tagatatctt gacagaagct gattttcaac aagttcgaac
    14161 ttatattcaa agtggaaata ttattcttga aagtaactta gctctcgaag aaatacgaga
    14221 acaggttcat actcta
//
LOCUS       DAVBED010000053        14106 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBED010000053 DAVBED010000000
VERSION     DAVBED010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.053"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..90
                     /locus_tag="VQ547_001696"
     CDS             <1..90
                     /locus_tag="VQ547_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2543512.1"
                     /translation="ISTTYRNHRKHFGLRMNLIAGIINHELGF"
     gene            complement(426..2117)
                     /locus_tag="VQ547_001697"
     CDS             complement(426..2117)
                     /locus_tag="VQ547_001697"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2543513.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2234..2698
                     /gene="argR"
                     /locus_tag="VQ547_001698"
     CDS             2234..2698
                     /gene="argR"
                     /locus_tag="VQ547_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2543514.1"
                     /translation="MHARGFYEKKRSSSVNKKMITEEKLSTQKEIQDRLEAHNVCVTQ
                     TTLSRDLREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKL
                     GEASVLANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2749..5283
                     /gene="mutS"
                     /locus_tag="VQ547_001699"
     CDS             2749..5283
                     /gene="mutS"
                     /locus_tag="VQ547_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2543515.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5430..7124
                     /gene="patA"
                     /locus_tag="VQ547_001700"
     CDS             5430..7124
                     /gene="patA"
                     /locus_tag="VQ547_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2543516.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7454..7723)
                     /locus_tag="VQ547_001701"
                     /pseudo
     CDS             complement(7454..7723)
                     /locus_tag="VQ547_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7915..9681
                     /gene="patB"
                     /locus_tag="VQ547_001702"
     CDS             7915..9681
                     /gene="patB"
                     /locus_tag="VQ547_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2543517.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9820..10509
                     /locus_tag="VQ547_001703"
     CDS             9820..10509
                     /locus_tag="VQ547_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2543518.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            10513..10692
                     /locus_tag="VQ547_001704"
     CDS             10513..10692
                     /locus_tag="VQ547_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543519.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10679..12028
                     /locus_tag="VQ547_001705"
     CDS             10679..12028
                     /locus_tag="VQ547_001705"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2543520.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12152..13612
                     /locus_tag="VQ547_001706"
     CDS             12152..13612
                     /locus_tag="VQ547_001706"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2543521.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13626..14060
                     /locus_tag="VQ547_001707"
     CDS             13626..14060
                     /locus_tag="VQ547_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2543522.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4124 a         2722 c         3182 g         4078 t
ORIGIN      
        1 atttcaacaa cctatcgaaa tcatcgtaaa cacttcggat tacgaatgaa tttgattgct
       61 ggcattatca atcatgaact aggattctag ttttgcagga agtctattat ttggttaggt
      121 gaattagtga agcgtttagg caagtgtctc tggttacgac gtcatggact ctaaatcgat
      181 tatatttagg ggtcatgact agtgaagcag ttagctagtt cgcatataag cggctagcgt
      241 ctaacaatta ggaactttag ttccaataac tttaagatta cgacgtttta ggacataaat
      301 cgatcatatt tatgtcctaa aactagtgaa gtatgtccta aaactagtga agcgcctagc
      361 caaagtccga ataggatttg gcgttagtta cttagattgc tttgcaatca agtaactttg
      421 gcgatttaca tcttctctgg cgcttctact ccaagcaagc gaagggcttc tttgagaacg
      481 actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc atccaagata
      541 cgtgtatgtg catagtattt gttaaaggat tgagccaggc taattgcaaa tttagcaatg
      601 atagaaggtt caaagttatc tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt
      661 ttaatgattt cccagctttc agtatcattc aagctatagt tgccagctgt ttctggtttg
      721 aaatcggctt tgcgtaagat agattggata cgagcgtagg catattgaac gtaaggtcca
      781 gtttcaccct cgaaggatac catagcctct aggtcgaagt cgtatccatt tgtacggtcg
      841 gttttgaggt catagaattt aatggctcca accccaacag catgtgctac ttggtctttg
      901 ttttctagtt caggattttt agcctcgatt tggaccttgg cacggctaac agcctctgca
      961 acagtaggct ctagcaagat gacattccct ttacgagtag agagtttctt cccttctttt
     1021 gtaaccaaac caaaaggaac gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc
     1081 aagacagctt tgagctgttt aaagtgggca gattgttctt gaccaacgac atagatagat
     1141 ttagcaaatt ggtattcgtt tttacggtag agggctgcag ccaagtcacg tgtgatatag
     1201 agagttgcac catcagactt cttgatgagg gctggatgtt caattccgta tttctcaaga
     1261 ttcacaactt gggcaccttc tgattcaaga agtagtcctt tttcagaaag aatgtctaca
     1321 actgcatcca tcttatcatt gtagaaggct tctccgttat agctgtcaaa ttcaaccttc
     1381 aattcattgt aaaggcggtt aaattccact aaactttcat cgcggaacca ttgccaaaga
     1441 gcgagagctt cctcatctcc attttcaagt ttacggaacc attcgcgcgc ttcttcatcc
     1501 aagctagggt cattttcagc ttcagcgttg atgcggacat agagtttaag gagttcatcg
     1561 attggatgag cttttacagc ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc
     1621 ccaaattgtt taccccagtc tcccaaatgg ttgaccttga ccgtttgata accgattttt
     1681 tggaaaatat gtgacaagct atctccgata acagttgaac gcaggtggcc aatagaaaat
     1741 ggtttagcga tattcggact agacatgtcg ataacaacat tttcttgttt accaatattt
     1801 tggtcagcat agtgttcttt ttcagtggta acagcttgca atacttgagc agaaatggca
     1861 gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga caactttttc aaaggcttgg
     1921 ctgttcattt tttcagccag ttcagccgca atcatttgtg gtgctttacg ttcgactttg
     1981 gcaagagaaa aagcagggaa agcgatgtca cccatttctg agtttttagg ggtttccagt
     2041 aactttaaaa tagcctcttg gtccaggcta tcaatgatgc tagccaattc gctagcaatc
     2101 aattcttttg tattcattaa gagctccttt ttggactttt ctactatttt atcacaattt
     2161 taaagaaaga agaaaaaatt tttgaaatct cctgtttttt tggtataata tggttataaa
     2221 tatagttata aatatgcacg caagaggatt ttatgagaaa aagagatcgt catcagttaa
     2281 taaaaaaatg attactgagg agaaattaag tacacaaaaa gaaattcaag atcggttgga
     2341 ggcgcacaat gtttgtgtga cgcagacaac cttgtctcgt gatttgcgcg aaatcggctt
     2401 gaccaaggtc aagaaaaatg atatggtgta ttatgtacta gtaaatgaga cagaaaagat
     2461 tgatttggtg gaatttttgt ctcatcattt agaaggtgtt gcaagagcag agtttacctt
     2521 ggtgcttcat accaaattgg gagaagcctc tgttttggca aatattgtag atgtaaataa
     2581 ggatgaatgg attttaggaa cagttgctgg tgccaatacc ttattggtta tttgtcgaga
     2641 tcagcacgtt gccaaactca tggaagatcg tttgctagat ttgatgaaag ataagtaagg
     2701 tcttgggagt tgctctcaag acttattttt gaaaaggaga gacagaaaat ggcgatagaa
     2761 aagctatcac ccggcatgca acagtatgtg gatattaaaa agcaatatcc agatgctttt
     2821 ttgctctttc ggatgggtga tttttatgaa ttattttatg aggatgcggt caatgctgcg
     2881 cagattctgg aaatttcctt aacgagtcgc aacaagaatg ccgacaatcc gatccctatg
     2941 gcgggtgttc cctatcattc tgcccaacag tatatcgatg tcttgattga gcagggttat
     3001 aaggtggcta tcgcagagca gatggaagat cctaaacaag cagttggggt tgttaaacga
     3061 gaggttgttc aggtcattac gccagggaca gtggtcgata gcagtaagct ggacagtcag
     3121 aataattttt tggttgccat agaccgcgaa ggcaatcaat ttggcctagc ttatatggat
     3181 ttggtgacgg gtgactttta tgtgacaggt cttttggatt tcacgctggt ttgtggggaa
     3241 atccgtaacc tcaaggctcg agaagtggtg ttgggttatg acttgtctga ggaagaagaa
     3301 caaatcctca gctgccagat gaatctggta ctctcttatg aaaaagaaag ctttgaagac
     3361 cttcatttat tggatttgcg attggcaacg gtggagcaaa cggcatctag taagctgctc
     3421 cagtatgttc atcggactca gatgagggaa ttgaaccacc tcaaacctgt tatccgctac
     3481 gaaattaagg atttcttgca gatggattat gcgaccaagg ctagtctgga tttggttgag
     3541 aatgctcgct caggtaagaa acaaggcagt cttttctggc ttttggatga aaccaaaacg
     3601 gctatgggga tgcgtctctt gcgttcttgg attcatcgcc ccttgattga taaggaacga
     3661 atcgtccaac gtcaagaagt agtgcaggtc tttctcgacc atttctttga gcgtagtgac
     3721 ttgacagaca gtctcaaggg tgtttatgac attgagcgct tggctagtcg tgtttctttt
     3781 ggcaaaacca atccaaagga tctcttgcag ttggcgacta ccttgtctag tgtgccacgg
     3841 attcgtgcga ttttagaagg gatggagcaa cctgctctag cctatctcat cgcacaactg
     3901 gatgcaatcc ctgagttgga gagtttgatt agcgcagcga ttgctcctga agctcctcat
     3961 gtgattacag atgggggaat tatccggact ggatttgatg agactttaga caagtatcgt
     4021 tgcgttctca gagaagggac tagctggatt gctgagattg aggctaagga gcgagaaaac
     4081 tctggtatca gcacgctcaa gattgactac aataaaaagg atggctacta ttttcatgtg
     4141 accaattcgc aactgggaaa tgtgccagcc cactttttcc gcaaggcgac gctgaaaaac
     4201 tcagaacgct ttggaaccga agaattagcc cgtatcgagg gagatatgct tgaggcgcgt
     4261 gagaagtcag ccaacctcga atacgaaata tttatgcgca ttcgtgaaga ggtcggcaag
     4321 tacatccagc gtttacaagc tttagcccaa ggaattgcga cggttgatgt cttacagagt
     4381 ctggcggttg tggctgaaac ccagcatttg attcgacctg agtttggtga cgattcacaa
     4441 attgatatcc ggaaagggcg ccatgctgtc gttgaaaagg ttatgggggc tcagacctat
     4501 attccaaata cgattcagat ggcagaagat accagtattc aactgattac agggccaaac
     4561 atgagtggga agtctaccta tatgcgtcag ttagccatga cggcggttat ggcccagctg
     4621 ggttcctatg ttcctgctga aagcgcccat ttaccgattt ttgatgcgat ttttacccgt
     4681 atcggagcag cagatgactt ggtttcgggt cagtcaacct ttatggtgga gatgatggag
     4741 gccaataatg ccatttcgca tgcgaccaag aactctctca ttctctttga tgaattggga
     4801 cgtggaactg caacttatga cgggatggct cttgctcagt ccatcatcga atatatccat
     4861 gagcacatcg gagctaagac cctctttgcg acccactacc atgagttgac tagtctggag
     4921 tctagtttac aacacttggt caatgtccac gtggcaactt tggagcagga tgggcaggtc
     4981 accttccttc acaagattga accgggacca gctgataaat cctacggtat ccatgttgcc
     5041 aagattgctg gcttgccagc agacctttta gcaagggcgg ataagatttt gactcagcta
     5101 gagaatcaag gaacagagaa tcctcctccc atgagacaaa ctagtgctgt cactgaacag
     5161 atttcactct ttgatagggc agaagagcat cctatcctag cagaattagc taaactggat
     5221 gtgtataata tgacacctat gcaggttatg aatgtcttag tagagttaaa acagaaacta
     5281 taaaaccaag actcactagt taatctagct gtagcaagga gacttctttg acaattctcc
     5341 acttttttgc tagaatgaca tcacacaaac agaatgaaaa ggagctgacg cattgtcgct
     5401 cccttttgtc tattttttaa ggagaaagta tgctgattca gaaaataaaa acctacaagt
     5461 ggcaggccct ggcttcgctc ctgatgacag gcttgatggt tgctagttca cttctgcaac
     5521 cgcgttatct gcaggaagtc ttaggcgccc tccttactgg gaaatatgaa gctatttata
     5581 gtatcggggc ttggttgatt ggtgtggccg tagtcggtct agttgctggt ggactcaatg
     5641 ttgtcctcgc agcctatatt gcccaaggag tttcatccga ccttcgggag gatgccttcc
     5701 gtaaaattca aaccttttct tatgctgata ttgaacaatt taatgcggga aatctagtcg
     5761 ttcgaatgac aaatgatatc aaccagattc agaacgttgt catgatgacc ttccagattc
     5821 ttttcagact tcccctcttg ttcatcggtt cgtttatcct agcggttcaa accttacctt
     5881 ctctgtggtg ggtgattgtt ctcatggtag tcttgatttt tggtttgact gctgtcatga
     5941 tgggaatgat ggggcctcgt tttgccaagt ttcaaaccct tcttgagcgc atcaatgcca
     6001 ttgccaagga aaatttacgt ggcgttcgtg tggtcaagtc ctttgtccaa gaaaaagagc
     6061 aatttgctaa gtttacagag gtctcagacg agcttcttgg tcaaaacctt tacattggtt
     6121 atgccttttc agtagtggaa ccctttatga tgttggttgg ttacggggcg gtcttcctct
     6181 ctatttggct ggtcgcggga atggttcagt cggatccgtc tgttgttggt tccatcgctt
     6241 cttttgttaa ttacctaagc cagattatct ttaccattgt tatggttgga tttttgggaa
     6301 attctgtcag ccgtgccatg atttccatgc gtcgtattcg agaaattctt gacgcagagc
     6361 cagctatgac cttcaaggat gtcccagatg aagagttggt tggaagcctt agctttgaaa
     6421 atgtgacctt tacctatcca atggacaagg aaccgatgct gaaagatgtg agctttacta
     6481 ttgaacctgg tcaaatggtt ggtgtagttg gagcgactgg tgcaggaaag tcaaccttgg
     6541 ctcaattgat tccacgtctc tttgatccac aggaaggggc tatcaaaatc ggaggtaagg
     6601 atattcgaga agtgagtgaa ggaaccctgc gtaaaacagt ttccatcgtt ctccaacgtg
     6661 ccattctttt tagtggaacg attgcagata acttgagaca ggggaaggga aatgctactc
     6721 tatttgaaat ggagcgcgca gccaatattg cccaggctag tgaattcatt catcgtatgg
     6781 agaaaacctt tgaaagtcca gttgaagaac ggggaaccaa tttctctggt ggacaaaaac
     6841 aaaggatgtc gattgcgcgt gggattgtca gcaatccacg tattctgatt tttgatgatt
     6901 cgacctcagc cttggatgcc aaatcagagc gcttggtgca agaagctttg aataaggact
     6961 tgaaggggac gacaaccatt attattgctc aaaaaattag ctcggttgtc catgcagaca
     7021 agatcttggt tctaaatcaa ggacgattga ttggtcaagg cacgcatgca gacttggttg
     7081 ccaacaatgc cgtttaccgt gaaatctatg aaacacagaa atgaaagaca aactataaga
     7141 aaagtcaata gttttatcta aactatttct tatttcaatt tgatgatttg gcgatgattt
     7201 tagagcacgg caaaaagccc ttgaaaaagt ccattttttc aaaggtaatc ctgtgttgat
     7261 ttcagaaatt acatcacttt ttgttcgtca aatggcagct cttttttagg atataaaaca
     7321 gggttcggat aagttttttt gcaaggtgga tgatggctac attgtaatgt tttccttgtt
     7381 ataacttagt cttaagatag gccttaaaag caggtgaaaa gtgagggcat gctttggcag
     7441 cttgtatgag tacctaccgc agatgagggg aaccccgttt gaccattctt ccagctaaat
     7501 caatctgacc tgactgataa atagaagaat ccagtccagc gaaagcttgt aattgagcag
     7561 gattatcaaa ggcatgaata tttcgaatct cggctaaaat gaccgcccct aaacgattcc
     7621 caatcccagt aaccgtcgtg atgaccgagt tgaactcagc catcaagtca ttgacacatt
     7681 tttccgcctt gtcaatgagc ctcttgtaat gtttgatgat ttcattacac gagataaaac
     7741 gtctatgcgt tatcaaactc attaccaatt aaaacaaaaa gctgtggtta gatcctttcg
     7801 gaaatcgtca agcgattgga ggaaatgaac taatccacag cggcttattc caagtatacc
     7861 acttgggctt tggcagtagc taactgcgct aaatataata taaggaggag taaaatgaag
     7921 acagttcaat ttttttggca ttattttaag gtctacaagt tctcatttgt agttgtcatc
     7981 ctgatgattg ttctggcgac ttttgcccaa gccctctttc cagtcttttc tggacaagcg
     8041 gtgacgcagc tagccaattt agttcaagct tatcaaaatg gcaatccaga acttgtatgg
     8101 caaagcctat caggaatcat ggtcaatctt ggcctgctgg ttttggttct atttatctct
     8161 agtgtaatat acatgtgtct catgacgcac gtgattgcag aatcgaccaa cgagatgcgc
     8221 aaaggcctct ttggtaagct tgctcagttg acggtttctt tctttgaccg tcgacaagat
     8281 ggcgatatct tgtctcattt taccagtgat ttggataata tcctccaagc ctttaacgaa
     8341 agcttgattc aggtcatgag caatattgtt ttatacattg gtctgattct tgtcatgttt
     8401 tcgagaaatg tgacgctggc tctcatcacc attgccagca ccccattggc tttccttatg
     8461 ctgattttca tcgtgaaaat ggcacgcaaa tacaccaacc tccagcagaa agaggtaggg
     8521 aagctcaacg cctatatgga tgagagcatc tcaggccaaa aagccgtgat tgtgcaagga
     8581 attcaagagg atatgatggc aggatttctt gaacaaaatg agcgcgtgcg caaggcaacc
     8641 tttaaaggaa gaatgttctc aggaattctt ttccctgtca tgaatgggat gagcctgatt
     8701 aatacagcca tcgtcatctt tgctggttcg gctgtacttt tgaatgataa gtctattgaa
     8761 acaagtacag ccctaggttt gattgttatg tttgcacaat tttcacagca gtactaccag
     8821 cctattatcc aagttgcagc gagttgggga agccttcagt tggcctttac tggagctgaa
     8881 cgaattcagg aaatgtttga tgcagaggag gaaatccgac ctgaaaaggc tccaaccttc
     8941 actaagttgc aagaaagtgt tgaaatcagt catatcgatt tttcatactt gcctgataaa
     9001 cctattttga aagatgtcag catttctgcc cctaaaggcc agatgacagc agttgttggg
     9061 ccgacaggtt caggaaaaac gactattatg aacctcatca atcgctttta tgatgttgat
     9121 gctggtggta tttattttga tggtaaagac attcgtggct atgacttaga tagtcttaga
     9181 agcaaggtgg gaattgtatt gcaagattcg gtcttgttta gcggaacgat tcgagacaat
     9241 atccgatttg gtgtgccaga tgctagtcag gaaatggttg aggtagcagc aaaagcaacc
     9301 cacattcacg actatatcga aagtttgcct gataagtacg atactcttat tgatgatgac
     9361 cagagcatct tttcaacagg gcagaagcaa ttgatttcaa tcgctcgaac cctgatgaca
     9421 gatccagaag ttctcattct cgatgaagca acttcaaacg tagatacggt gacagaaagc
     9481 aagattcagc atgccatgga ggtggttgta gcaggtagaa ctagtttcgt cattgcccac
     9541 cgcttgaaaa ccattctcaa tgcagatcag attattgtcc ttaaagatgg agaagtcatt
     9601 gaacgtggta accaccatga acttttgaag ctaggtggct tttattcaga actctatcac
     9661 aatcaatttg ttttcgaata agaaagaagt tgtcctatgt gggcagcttt ttcttgtcca
     9721 taaaaaatgt ttatcacagc cttaaaaaaa acatattaga cgaaagtcat tttgagtgat
     9781 atgataggac tatcgttagc attcgaaagg agaggcatca tggctagaac ggttgtagga
     9841 gttgctgcaa atctatgtcc cgtagacgca gaaggcaaaa tcattcattc atctgtatct
     9901 tgtagattcg cagagatcat tcgtcaagtc ggtggtctcc ctttagtcat tcctgttggt
     9961 gatgagtcag ttgtacgtga ttatgtggaa atgattgaca aactcatttt gacaggaggc
    10021 caaaatgttc atcctcagtt ttatggagag aaaaagaccg tcgagagcga tgattacaat
    10081 ctggtccgtg acgaatttga attggcactc ttgaaggaag cgcttcgtca gaataaacca
    10141 attatggcaa tctgtcgcgg tgtccaactt gtcaatgttg cctttggtgg aaccctcaat
    10201 caagaaatcg aaggtcactg gcaaggacta cctttcggga catctcactc tattgagaca
    10261 gtagaaggaa gcgtggtggc taagctattt gggaaagaaa gtcaggtcaa ctcagtccat
    10321 cgtcaaagca ttaaagattt ggcacctaat ttccgtgtaa ctgctattga ttcaagagac
    10381 caaactattg aagcgattga gtctatcgac gagcaccgca ttatcggttt acagtggcat
    10441 ccagagtttc tggttaatga agaagatggc aatttagaat tatttgagta tttattggat
    10501 gaactgtaac aattggaaca tctggtcgtt ctttctttta ttttttcaaa atttttagaa
    10561 tgtggtattt tacgcaaacg tttgaattct gataaaaatt ggagaaattc gacaaaaaaa
    10621 cttgaaaaaa acgaaggtaa gcgttatgat agaaaagaag aaatattgga ggaagaacat
    10681 gtcacatatt aaatttgatt attcaaaagt tttagacaaa tttgttgcac cacatgaagt
    10741 ggaatacatg caatcacaag taacagcagc agatgaattg atccgtaaag gaactggtgc
    10801 tggtagcgac ttcttgggat ggttggacct tcctgaaaaa tacgaccgcg aagaatttga
    10861 ccgcatcttg aaagctgctg agcaaatcaa gtcagacagc gatgttttgg ttgtgatcgg
    10921 tattggtgga tcttaccttg gtgcaaaagc agcaatcgac ttcttgaatc accattttgc
    10981 taacttgcaa acaaaagaag aacgcaaagc tccacaaatc ctttacgcag gaaactcaat
    11041 ctcatctact taccttgctg acttggtaga gtatgttgca gacaaagact tctcagtaaa
    11101 cgtaatttct aaatcaggta caacaactga accagcgatt gctttccgtg tctttaaaga
    11161 actcttggtt aagaaatacg gtcaagaaga agctaacaaa cgtatctatg caacaactga
    11221 ccgccaaaag ggtgctgtta aggttgaagc agacgctaac ggttggggaa catttgttgt
    11281 tccagatgat atcggtggac gcttctcagt attgacagcc gttggtttgc ttccaatcgc
    11341 agcatcagga gctgacataa aagctcttat ggaaggtgcg aatgcagctc gcaaagacta
    11401 cacttcagac aaaatctctg aaaacgaagc ttaccaatac gcagctgttc gtaacatcct
    11461 ttatcgtaaa ggctatgcaa ctgagatctt ggtaaactat gagccatcac ttcaatactt
    11521 ctcagaatgg tggaaacaat tggctggtga atcagaagga aaagaccaaa aaggtatcta
    11581 cccaacttca gccaacttct caactgactt gcactcactt ggtcaattta tccaagaagg
    11641 aactcgtatc atgtttgaaa cagttgtccg tgttgacaaa cctcgtaaaa acgtgcttat
    11701 tcctactttg gaagaagacc ttgacggact tggttacctt caaggaaaag acgttgactt
    11761 tgtaaacaaa aaagcaactg acggtgttct tcttgcccac acagatggtg atgtaccaaa
    11821 catgtatgtg actcttccag agcaagacgc tttcactctt ggttacacta tctacttctt
    11881 cgaattggca attgcccttt caggttactt gaatgctatc aacccatttg accaaccagg
    11941 tgttgaagct tataaacgta acatgtttgc ccttcttgga aaaccaggat ttgaagaatt
    12001 gagcaaagaa cttaacgcac gtctataata gaagaaaaga gtggtttgcc cactcttttt
    12061 actctcttta tccatagaaa ttggactcag ccaagacttg tgatataata tagaaagcaa
    12121 aaaggcagac gcctagataa taggagaaac tatgtcaaaa gatatccgcg tacgttacgc
    12181 accaagtcca acaggactac tacacatagg aaatgctcgt acagcattgt ttaattactt
    12241 gtatgcgcgc catcatggtg gaacatttct catccgtatc gaagatactg accgtaaacg
    12301 ccatgtcgag gatggtgaac gttcacaact tgaaaacctt cgctggttag gcatggattg
    12361 ggatgaaagt ccagaatcac atgagaatta tcgccagtct gagcgtttgg acttgtatca
    12421 aaaatacatc gaccaactat tagctgaagg aaaagcctac aaatcttacg ttacagaaga
    12481 agagttggca gctgaacgtg aacgtcaaga agtagctggc gaaacaccac gctacatcaa
    12541 tgaatacctt ggtatgagtg aagaagaaaa agcagcttac atcgcagaac gtgaagcagc
    12601 agggatcatc ccaactgttc gtttggctgt caatgagtca ggtatctaca agtggcatga
    12661 tatggtcaaa ggcgatatcg aatttgaagg tggcaatatc ggtggtgact gggttatcca
    12721 aaagaaagac ggttacccaa cttacaactt tgccgttgtt atcgatgacc acgatatgca
    12781 aatctctcat gttatccgtg gagatgacca tattgctaat acaccaaaac agcttatggt
    12841 ctatgaagct cttggttggg aagctccaga gttcggtcac atgaccttga ttatcaactc
    12901 tgagactggt aagaagttat ctaaacgtga tactaataca cttcaattta tcgaagatta
    12961 ccgaaagaaa ggttaccttc cagaagcagt ctttaatttt attgctcttc ttggttggaa
    13021 cccaggtggt gaagatgaga ttttctctcg tgaagaactc attaaacttt ttgatgaaaa
    13081 ccgcctcagc aagtcaccag cagcctttga tcagaaaaaa ctagactgga tgagcaatga
    13141 ttatatcaag aatgcagacc ttgaaaccat ctttgaaatg gcaaaaccat tcttagagga
    13201 agcaggccgt ttgactgaca aggctgaaaa attagttgag ctctataaac cacaaatgaa
    13261 atcagtagat gagattatcc cattgacaga tcttttcttc tcagatttcc cagaattgac
    13321 agaagcagag cgcgaagtca tgacgggtga aacagttcca acagttcttg aagcattcaa
    13381 agcaaaactt gaagcgatga cagatgataa atttgtgaca gaaaatatct tcccacaaat
    13441 taaagcagtt caaaaagaaa caggtattaa agggaaaaat cttttcatgc ctattcgtat
    13501 cgcagtttca ggcgaaatgc atgggccaga attaccagat acaattttct tgcttggacg
    13561 tgaaaaatca attcagcata tcgaaaacat gctaaaagaa atctctaaat aaagaggata
    13621 caataatgga catctgggaa aagatgtacg aagaagcaca gaaactatac aatccacatg
    13681 aagtatcaga ctttgtttat gccaatcatg ttgtagctgc agtagaagca gaagatggac
    13741 aaatatttac aggattctgt atggagggaa cctgtggtgt tttccatctc tgcgcagaac
    13801 gggcggccct cttcaatacg taccaatttt caggacaaac taaggttaag aaagtattag
    13861 cctttcgaga caaaccacct tatggtggaa gttcagccat gccttgcggt gcttgtagag
    13921 aattcctttt agagcttaat gctgaaaata aagatgcaga attcatgatg gactataata
    13981 taagaaaaac agttaaagtc gcagaactaa tcccttattg gtggggagaa gaacgtgctt
    14041 ctaagtttaa tgagcgatag aagagtcagt ataattctgg ctttttttac tataagttga
    14101 aaaaat
//
LOCUS       DAVBED010000054        14039 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBED010000054 DAVBED010000000
VERSION     DAVBED010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.054"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQ547_001708"
     CDS             98..1357
                     /locus_tag="VQ547_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2543523.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQ547_001709"
     CDS             1607..2107
                     /locus_tag="VQ547_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2543524.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQ547_001710"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQ547_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2543525.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQ547_001711"
     CDS             2738..2908
                     /locus_tag="VQ547_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543526.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQ547_001712"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQ547_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQ547_001713"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQ547_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQ547_001714"
     CDS             3503..3883
                     /locus_tag="VQ547_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2543527.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3896..4039
                     /locus_tag="VQ547_001715"
     CDS             3896..4039
                     /locus_tag="VQ547_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543528.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4132..4719
                     /locus_tag="VQ547_001716"
     CDS             4132..4719
                     /locus_tag="VQ547_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543529.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4921..5058
                     /locus_tag="VQ547_001717"
     CDS             4921..5058
                     /locus_tag="VQ547_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2543530.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5237..7846
                     /locus_tag="VQ547_001718"
     CDS             5237..7846
                     /locus_tag="VQ547_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2543531.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7879..9819
                     /locus_tag="VQ547_001719"
     CDS             7879..9819
                     /locus_tag="VQ547_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2543532.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9816..11423
                     /locus_tag="VQ547_001720"
     CDS             9816..11423
                     /locus_tag="VQ547_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543533.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11438..12178
                     /locus_tag="VQ547_001721"
     CDS             11438..12178
                     /locus_tag="VQ547_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543534.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12181..13500
                     /locus_tag="VQ547_001722"
     CDS             12181..13500
                     /locus_tag="VQ547_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543535.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13634..13771
                     /locus_tag="VQ547_001723"
     CDS             13634..13771
                     /locus_tag="VQ547_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2543536.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4691 a         1960 c         2777 g         4611 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca gctggattga
     3961 gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta
     4021 tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat gggtagaaag
     4081 gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga
     4141 ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct atacttattg
     4201 aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc gtcactcatt
     4261 tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat gaaatctagg
     4321 atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg ttttagtctg
     4381 attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca tcaaattcct
     4441 tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga
     4501 gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac aagtgtttta
     4561 tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt ttcacttggg
     4621 atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg actacatttg
     4681 gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc tgatttttag
     4741 gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt tgaaaagtta
     4801 cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta ctggtggaga
     4861 gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga ggagctagct
     4921 atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga aacagatgaa
     4981 gttgatggaa tgcgatttag tacattcagt acaaatcgtt gcggtaactg gagtgctttt
     5041 agttgggaaa attgttaatt catttaaatt gtaaacttta gagattctct ggagttatgg
     5101 atgtcgttcc aatatgtgca cgttggaatg ttagtgctta tatggggaga atccaaagga
     5161 ttctcccttt ttatttaaat aagtctgtct agctatagat atattaagtt tgataaaatt
     5221 tcttggagat tttgttatgg attataattt caatttggag catcctttct ttttcactaa
     5281 taatgattat agtacagata ctagcataaa gtaccaagta agtctgcctt ttaattggca
     5341 cgaagtaatg aataatgatg agtgggttta tcaataccct attggaaaat ttgttgaaag
     5401 acaagggtgg aaaatacaca ttagttcaga gtataacagt tcacatgaat tgttacaaga
     5461 tgtagcaaaa atttgccatg aaatgcgaat tccatttaaa catcttagta cagaagacaa
     5521 atttatcatg cgaaacggga aattggttag tcgaggattt tctggtaaat ttattacatg
     5581 ttatccaaat caaaatgaat tagagtcggt tttgcaaagg ttagaaagtg ccttaaagca
     5641 atataatggg ccatatattt taagcgataa acgttgggat gaagcaccaa tatatctgag
     5701 gtatggtgtg tttaggccgt caagggatga tgaaaagaag gttgctattg atgaattaat
     5761 tgttggcgat gaagttgtta aagatgaacg tttaccagta tttaaaattc caaaaggtat
     5821 agtgccccct gactttttga ataaatggct tgacaagaaa gataaaaaac agggagactt
     5881 tccctttatt atagataatg caattagatt ttcaaacagt ggtgggatat ataatgctag
     5941 gctaaaagaa gatgggaaaa aaataatttt aaaagaggct agaccgtata caggtctagg
     6001 atttgatggt acttattctt cagagaaatt agcttcggag tgcaaagcac taaaaattct
     6061 aaatgaatgg agtgagacgc ctaaaatata ctggcacggt aagatctggg agcacacctt
     6121 cttaggaatt gaacatatga agggcgttcc actaaataga tgggttacca ataattttcc
     6181 tttatatgaa gttgttgata agaccaaaga ttatctattg agagtttcaa agatagtaga
     6241 aaaactcatc gatttaacga ataagtttca ttctgaaaat gtatatcatc aagatttaca
     6301 tttaggaaat atcttggtta aggatgaaga tgagattagt ataatagact gggaacaggc
     6361 tgtcttttca aatgatgaaa aagttgtaca taaagttgca gcccctggtt ttagagcatg
     6421 gcgagaaaca cttcccagtg agatagattg gtatggtatt agacaaatag ctcattattt
     6481 atacatgcca ctagtaacta catcggattt gacatacaac tatgtaagtc aaaccaggat
     6541 agaaggaaaa aaactatttg agtctttggg ttatacaaga gaacatatag attatgtaga
     6601 aagtttattg tcatatctag attctaaatg tccacagatt gagaatattt ccaggaaaaa
     6661 agttttaaaa cccatgcatg agattagaac tatcgagagt gagcaagata tacaagattt
     6721 tattataaaa ttattgagag ggtttacgct aacttatgga cagtggcgta aagaatttca
     6781 atcaagattc ttcccagttc attattatgg tctgaatttt aatcaaggaa ttgcgttttc
     6841 agatttagct atcctttgga gttatcaaca actagctaag aaagtaaaaa atttcaagtt
     6901 tgatgactat tatgagattc gaacacaggt tattaatgag gcagtaaata attttaagaa
     6961 atcgtccctt tctggtcttt ttgatggtaa aattggtaca atctggctca tttatgaatt
     7021 tggggagata gatcgggcag ttgaactttt tacaactcat tttatagaga tatttgagaa
     7081 ttcacaaaat aaaaatttat atagtgggca ggctggaatt ttactggttg gactgtattt
     7141 tcttagtaaa ggggaaattg ataataaact aggagaagaa atactaatta ggcttagaga
     7201 atatacttta aattatatag aaaatccaga aactttttgt aaagttggcg ctagtgatgt
     7261 tcagagtaat gatccttatg agaattttgg tggattacta tatggtcacg caggggtagc
     7321 ttggctcttc ggtgaagctt ataaattaac tggtgaaagt atctataaaa atggtctaga
     7381 attggctgta gataaagaat tagttgctta taaagtagat agtaataatt cattgcagta
     7441 cagccaaggt catagattac taccatatct agcaactgga agtgctggcc tgcttttact
     7501 tattaataga aataaagaaa tcttgtcaag caaatactta aaatatttaa cttctttaga
     7561 gagggcaact gatgtagttt tttgtgtatt accaggttta tttaacggat tttgtggtct
     7621 tgaagttgct aataatatat atagtgatat cgatgataac ttttcaggac aaaagaaatt
     7681 aattgaacaa ctttatagat atttgtgtgt aattgaagaa ggatttgtta ttgcgggaga
     7741 taatggttta aagataacaa cagatattgc ttcgggattt gcgggtgttg caattggatt
     7801 ggtatcaata atggataata aattgacgat tcttcctcaa atataatatt tagataccat
     7861 tattaagggg tcatacttgt gaatcagagt aatgaaatat ttttaaatac aatacaggaa
     7921 aaaacacact ataagaggtc tatctcttca tcatttcagg aattaaaaaa atggaattct
     7981 ttgatattta ggagagggcg atattggtac caatttgata attggagtat acccaatact
     8041 ggtgtaataa aggaatggta tgtcgaagat aatgactgga ttcctaaggt tagttcttcc
     8101 agtttagaca attcaaattc acttaaaatt gtctttgatg tggaaaaata tactttgcca
     8161 gatgatagta tcttacagga tgttaggatt tcatctgatg agagttatat agttttggtt
     8221 gtatcctcac tgcgtagcac taatttaatt ggaataaaaa aatatactat ggaagagtta
     8281 tttatcattg aagatatttc agtagaaagt tcgttctatt tgggtaaatt cggtgttatg
     8341 tatactcgct ccaaagagta cgggaggcca agtaagttat tctataaatc ttttgatagc
     8401 tttacagaag aggaactgtt tgaagaaaac gaatgctctt ttcgattaaa aatagtccac
     8461 attgatagca ataattgttt tgtaaagtca gtagactttc agaaaggcag gatttttcta
     8521 tacagtttcg accggacggg ttttgttaga cactcttaca cagaaacggt agccccaaca
     8581 cctagagata tcgctctatt tagtacagaa aaagcacagt actttcttgg gctctcttca
     8641 actgaagaaa agaaagatca actaattcta agggaaactt cttcgggaga cagagtttct
     8701 attactatac catatcaaga tagggctaga agagttcact gtataggacg ttatatcctt
     8761 ttagactgtt caaacgcagc gaattccgtc ttttatcttg ctacatttaa aaataatagt
     8821 ttgagggagt tgagtgttaa taagataaca tttgatgaaa agacaacact ttatgaaaat
     8881 tcattttctg atcgtgttct tctgttttta gagaggagaa ctttttacga aaaaatactt
     8941 agttttgatt taatagaaaa tacattaaaa actgaatttg aaagacccat cataaaatcg
     9001 aataatacta aatatttttc taaggtgatt tggactaaaa aagacagtta tgatgtaagc
     9061 ataccgattt ctttattttg gaaaagtgaa gatacggatg agctcccaag aagaaaaaaa
     9121 tgtattctaa gtgtctatgg ggcttatggt aagaatgata attctgattt agatgaaatt
     9181 atgttatcta taatagatgc aggttttatt tatgctatag ttcatgtaag aggtggaggc
     9241 tatttgggtg gtgaatggta tcgctcagga aaggcgttaa acaaatggaa ttctatcaga
     9301 gattttattg agggagtaaa ttatttaagg gaaaatgatg taattgacag taagcgatta
     9361 ggtttaataa cttctagtgc aggtggaata attgctggtg cggtgttgaa cgaggaaaaa
     9421 aatttattgc aaagcattct cttattttcg ccatttataa atccttatga tacacttcag
     9481 aatccaaatg atcctctttc taagaccgaa atagcagagt ggggagatat tagagaccct
     9541 gaagtaaagg cttatataaa gtcatattcg cctatgcaaa atattgaaaa ggcacgagac
     9601 tcaaatactg ttatagttaa tattttgggt gagaaagacc catatattaa taataacgaa
     9661 gtgatagagt ggtcaaagaa attaaattct attggagtta aaagtttgtt gtatttaaac
     9721 aaagcagctg gtcatggagg ttttactcca tcagatgttc tcttaatgat tgatacttta
     9781 aattatttct ttgaagaagt gggaaggaat aacttatgaa ttatttaaaa tttataaaaa
     9841 agactaaact tatattaatg gggattttaa tatttctatc ttcgtttaat ggtgtcttgc
     9901 tctcaggaat tattgtatat gcaggtagtt taaatcagac ttcctcattt tctgacgttc
     9961 taagatttgg tgctataagt attctgggtt ggtcagcaat ctatatatca aattactatt
    10021 tagaagtaac ggaagcatca ataacgaaag atataaatgt aaaaattaaa caaggatatt
    10081 ttagagaaca gtatctttct tctgaaatgg ttaaagatta ctcatctatt atttcagttt
    10141 tgtcaaatga tttgagatta atcgaagaaa actattttag acaaattttt gaaataattt
    10201 cttcaatatt gttgttcatc gtctctctaa gttttatgct ttatttaaac ttcctagttt
    10261 caataatatt tattgtatta tcagcattgc cgattatagt acctgtcttt atgaagaaga
    10321 tgttgtctaa ttcagctaat gagtactcta acagcaatgc agagtatact cacataataa
    10381 aagaaatttt taatggtttt aagacattaa aatcttattc tgttactaaa gaaataatta
    10441 gtttgtcgga taaaaagttg gataaactag aagattctac ttttaatttg aaacgatcag
    10501 aggttctttc aaaattggtt gcagtactaa tttcaggttt ttgctttcta gttcccttgg
    10561 ttgtaggatg ttattttgta atttatcata aaagcctttc ttttagtgaa ctgataggta
    10621 ttttcttagc aaacgataaa gttttagggc cgatacaatc aattgcctat tcattaaata
    10681 agataaatac aaccaaagat ttaaggaaac cgtttttaaa atacttaagt ggagagaaga
    10741 attttataga cgctgaacat gataataacg gactgtatac ttcatcaata gatgagatac
    10801 acatgaaaga tgttgtatat tctattacac cagaaaataa attaagtatt gacttctcat
    10861 ttaagtcacc atttagggta ttattaacag gaacttctgg tagtgggaaa acaacgattt
    10921 taaatttaat taatggttct ttaaagccac aaaaaggtta tgtaaatttg ttatcacatg
    10981 ggaaaaagag ttcagattca ataccaacag ttgatcagac accatatatt tttgacacta
    11041 ctattcgtga gaacgtaact ttatttcaaa atgaatattt ttcagatgat cagataattg
    11101 aggtgttaaa aaaggtaaat ctatatgaag aattagaaaa gatagatata ctaaattatc
    11161 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
    11221 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
    11281 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
    11341 tttcacatca ttatgactta aatgacaaga gatacactga tatatataaa ttggaaaatg
    11401 gaacactttt caaaattaag tgattggagg caagaatatg gataaagatt atatattaaa
    11461 agtgaaaggg ctgtatcatc aatttttact aggaaataat aaaacgttgc aagtgctgaa
    11521 aaatgtttct ctttctgctt cgagaggaga atttataagt attctaggaa ttagtggttc
    11581 tggaaagtca actttattaa aatgtatttc tagtttgctt gaaccaacaa gtggggaagt
    11641 aattttaaat ggaatcaacc cctataaaat cagaaatgca aaattgtcaa gtataagacg
    11701 taacgaagta tcttttatat ttcaagcata caatttaata ccttccctgc cggtaataga
    11761 aaatatagca cttcctttgc gattatcaca aaaaaaatta actattaaaa atgtagaaaa
    11821 cttactcaaa agaatgaagt ttaatgctgg cttaaacgat tttgttggaa ctctgtctgg
    11881 tggagaacaa cagaaggttg ctatagctag agcggttatt gctgatagtg atataatatt
    11941 tgctgatgag ccaactgggg ctttagacag cgtttctcgt gaagtaattt ttgaattatt
    12001 gagagagtta gtaggggcgg gtaagtgtgt aattatggta acgcacgata tagaattggc
    12061 ctcgaaaact gatcgtgcat taatattgaa agatggaaaa attttcaaag aacttcatag
    12121 acctagcggg gaagagttgt ataaaatctt agaggtacaa tcaactacgg aggaatagag
    12181 atgctcagat tagtttacta tcaattttta cataataaga aacaatggtt aggcgtttca
    12241 ccagtaattt ttgtttcgag tttagttatg ggattggctg ttaatggggt aattaatgtt
    12301 gagaataatt cgcaagtatt tgtcggactt ccagatccta aaccaatttt tatgtttccg
    12361 atagtattcg gaggagtaac attattcttt gtgctctcta acataataaa tatgttggtt
    12421 gaaattttta gagatgatta cgaacttctg gaggtgttgg gagcaagtct ccttcaacta
    12481 tcatttcttg tggggggaca gatttttatc atttcctcga ttattagttt tattgcatat
    12541 ctatgctcta tatttgttac gtcaaattat tattattttt tacaatactt tttcggggaa
    12601 aatatattac ctgatatcca atttcaaacg agtgctgttg gatgtatcat tacagtagtg
    12661 ttgatttcat ttttagcctt tctaagtggt tgcttttata cgttcaagaa gattagaaat
    12721 aggaagagtt ctaaaataag gcatgttctt tcaatagtaa aaagaatact gctattggct
    12781 ggttttagtg ttatctggtt gctttctttg caacaaattt tccaagatag cacaatttta
    12841 gcgaaggccc agataatatt caatattgta atcttagata ttgtgattat ttatcaatta
    12901 tctcctttta tacagtcatg ttttatcaaa ctactttcta taattatatt tagaaataat
    12961 tttatgttca ttgcttcgaa gtggaattta ctatatcgta agccttatat aaaatctatc
    13021 agtgctgcaa ttacaggagc tatattacta atttctagtt ttcaaatgat ttctcagaat
    13081 atactatctc aatttcaaga tgacagtgat ttagagctaa aagtggcatt tattgtctat
    13141 gtaggagcac caattttgat agtacttgca aatattattt caattgcatt tttgtcatcg
    13201 catcaagaaa ggattgagat tcagcaattt gaaattttag gaacttctaa ttaccagatg
    13261 gttaagatta aagttggtga ggctatattt ttgacatttg ttacttcatt aattgcattt
    13321 ttacttaaca ttaaaattat ggctttaata tactactctt tagaggatgt tttaatagat
    13381 gatatgaatc ttttggggtt aatacttcca aattttatag tgtctattat tttatttatt
    13441 ttaatattta ttactaaaag ttcctatttt atctttaaga atgcaaaaat tatttcttaa
    13501 aaatttgtaa gttttcgcta tataaaatag ttaaatctat tttgtatcat tgcttgcatt
    13561 ttactggtgg agagaatata atgagggtgg ataaagtact taatcccaaa aatttaaata
    13621 ggaggagcta gctatggcag aagaagtatt aaatcttcaa ttagtatctg ttcaagttga
    13681 cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaacc gttgcggtaa
    13741 ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact ttagggattc
    13801 tctgaagtta tggatgtcgt tccaatatgt gtacgttgga atgttagtgc ttatatgggg
    13861 ggaacagaat cctctcttga ttgaagacaa gttagccatt aggctggttt gtctctttgt
    13921 caactgtagt gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta
    13981 ttcagtacaa atttaacggg tcaagattta ttgaactgca ccccaatagt tagacagaa
//
LOCUS       DAVBED010000055        14013 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBED010000055 DAVBED010000000
VERSION     DAVBED010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.055"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(122..1972)
                     /locus_tag="VQ547_001724"
     CDS             complement(122..1972)
                     /locus_tag="VQ547_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2543537.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2040..3179)
                     /locus_tag="VQ547_001725"
     CDS             complement(2040..3179)
                     /locus_tag="VQ547_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2543538.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3237..4403
                     /locus_tag="VQ547_001726"
     CDS             3237..4403
                     /locus_tag="VQ547_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2543539.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4542..4868
                     /locus_tag="VQ547_001727"
     CDS             4542..4868
                     /locus_tag="VQ547_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2543540.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4855..5448
                     /locus_tag="VQ547_001728"
     CDS             4855..5448
                     /locus_tag="VQ547_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2543541.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5441..6352
                     /locus_tag="VQ547_001729"
     CDS             5441..6352
                     /locus_tag="VQ547_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2543542.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6415..7479
                     /locus_tag="VQ547_001730"
     CDS             6415..7479
                     /locus_tag="VQ547_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543543.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7551..8411)
                     /locus_tag="VQ547_001731"
     CDS             complement(7551..8411)
                     /locus_tag="VQ547_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2543544.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8533..9519)
                     /locus_tag="VQ547_001732"
     CDS             complement(8533..9519)
                     /locus_tag="VQ547_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2543545.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9791..11266)
                     /locus_tag="VQ547_001733"
     CDS             complement(9791..11266)
                     /locus_tag="VQ547_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2543546.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11370..12293)
                     /locus_tag="VQ547_001734"
     CDS             complement(11370..12293)
                     /locus_tag="VQ547_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2543547.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12307..13236)
                     /locus_tag="VQ547_001735"
     CDS             complement(12307..13236)
                     /locus_tag="VQ547_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2543548.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13555..13905)
                     /locus_tag="VQ547_001736"
     CDS             complement(13555..13905)
                     /locus_tag="VQ547_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543549.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         4190 a         3027 c         2582 g         4214 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg atttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tatttaactt gataatatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta ggcaccttgg cttcatcaac ggctctagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaagagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 taaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatac
     1741 tcgcgctcaa gccccaaaaa tcaaccatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgtgag ttttttattc atagaaattt
     1981 actcctcctt aaaatagttc tactatattg ttattatagc acattttaat ttatttggct
     2041 tatttttcca aataaattac tgttcccttg tactccttct tccatttaaa tcctctaatt
     2101 aaacctacaa tcgtcccaag gccataagca aagtgaatgg aaaataaaag aaagggcatc
     2161 acaattagaa atccattttt atgttttaat aaagtcagca aagtgagtaa tgacagtaat
     2221 gataaaagta gaaaataggc acctaatagt aaagttatga atacgaatgt gatcggtaac
     2281 aatgctagac taaacacaag actcaaaaca aataaacaag gaacataatg aaataatgat
     2341 aaacacttaa actgaacatg acttgtcaag ccaatccaca aaccatttga atacttttga
     2401 tgcagcattt tcttgaatgt tggtcgaata tactgataag atagaatact tgggctatag
     2461 cggattttat aaccatgttc tcgaattcta taatgaatat cattatcttc agttcggcca
     2521 agttgctcat ttactaaacc aaccttctgg aaaacctctc gtttatacat cccatgaaaa
     2581 atagaagaaa catatctatc ctcggaacta tttcgataat tggcaatgct actgccaaac
     2641 atattttcct caacaagatg caaggtctct gcccattttc cttttccttt gacaatcgtc
     2701 ggtctaggcc ctccacagac aaattcacct tgttgaataa cagccacatt gttcattaca
     2761 aaactctcag taacttttga atgagcatca atttttaaaa taaggccccc tacagaatgc
     2821 ttaactccca ggttaaaacc actagcttga tttttcttag gattgttata caatctaatt
     2881 gagttaaact ctgcatcttc ttttataaat tgctgaatga tagctgtggt cccatctgtg
     2941 gacatagcat ttataaatag aatttcaata ttctctttag gataggtttg attttttaag
     3001 tcttcaatta gaccaggcag atatttttct tcattgtatg cactgattac aatggatacg
     3061 agaagacttt caacattttg agtcactact actctcctga attttccctt ccaccattct
     3121 atcataattt tcaagacttt tccattttta tcttgaaagc cagaaacctt acttgacatt
     3181 atagtgaaaa agccttaaaa taagctgtta ttaaaatcag ctagaagaga tattatatga
     3241 aaaagcaatc actctttttt gttccaggta ttatcctgat tggtgtttcc ttgcgaactc
     3301 cttttactgt tttacccatt attttgggaa atatttcgca aggtctggag gtagaagtta
     3361 gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt taccctcttt tcaccatttt
     3421 ctacccgact ggctcagaaa atcggcttgg agcatctctt cacctacagc ctcttcttct
     3481 tgaccatcgg ctcacttatt cgactaatca atctgcccct gctctatcta ggaaccttga
     3541 tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc tagtcttatc caagccaatc
     3601 aaccaaagaa aattggtttt ctgaccacct tatatgtaac gtctatgggg attgcaacgg
     3661 ctctggcttc ctatctagct gtgcccatta cacaagccag ttcttggaaa ggacttatcc
     3721 tcctcctcac gttactctgt ctagcaactt ttttggtctg gctcccaaat caccgctata
     3781 atcatagact agctccacaa accaaacaaa aaagtcaaat aaaggtcatg cgtaataaac
     3841 aggtttgggc aattattatc ttttcaggtt ttcaatcctt gatcttttac accgccatga
     3901 cctggttacc taccatgtct atccatgcag gtctatccag tcacgaagct ggcttgctga
     3961 cttctatctt atctctgatt agcattcctt tttcaatgac catcccaagc ctgacaacca
     4021 gtttatctac tcgcaaccgt cagctcatgc tcactctggt ttcactagct ggtgtggtcg
     4081 gcatttccat gctctttttc ccaatcaata atttcattta ctggcttgcc atccatctcc
     4141 tcatcggaac cgcaaccagc gccctcttcc cttatctcat ggtcaacttt tcactcaaga
     4201 ccagcgcccc tgaaaagaca gcccaattgt ccggcctatc tcaaacagga ggctatatcc
     4261 tagcagcctt tgggccaacc ctctttggtt acagttttga cctattccac tcttgggtac
     4321 cagctgtagc tgccctcttg ctcatcgata tcctgatgac tgtggccctc tttacagtgg
     4381 acagagcgga taagatcctt taaacttcta gttttagcta gaagtttttt atatataaaa
     4441 attttacaca tttctcttga cagggctttc ttttagatgt acaatgtatg tgtagaaaaa
     4501 ttatatataa aaatcttaca cattagaaaa ggaggtttcc catgtacttt ccaacatcct
     4561 ctgccttgat tgaatttctc atcttggctg tactggagca gggtgattct tatggttatg
     4621 agattagcca aaccattaag ctgatcgcta atatcaaaga atccacactc tatcccattc
     4681 tcaaaaaatt ggaaggcaat agctttctga caacctattc tagagagttc caaggtcgca
     4741 tgcgcaaata ctactccttg acaaacggtg gtatagagca gctcttgacc ctaaaagatg
     4801 aatggacact ctatacagac accatcaatg gcatcataga agggagtatc cgccatgaca
     4861 agaactgaat acctgactca gctagaactc tatctcaaga aactacctga agctgaccgt
     4921 atcgaagcca tggactattt cagagagctc tttgacgatg ctggagtcga aggagaagaa
     4981 gaactcatcg ctagtttggg aactcccaaa gaagtggccc acgaagttct atccaatctt
     5041 ctcgataaaa aaatcaatga agcacccgct caaaaaaata accgacaaat tttacatatc
     5101 gccttgttag ccctccttgc agcacctatc ggcattcctc tgggaatcgc catcctcgtg
     5161 accctgttcg caatccttgt agccgctttg actgtcattc tggctttctt tgcagtttcc
     5221 atactgggta tcatcggcgg attcctattt ttagttgaaa gtttcactgt cctcgcccaa
     5281 gccaaatcag cctttatctt gatttttggt tctggtttac tggctatcgg tgcttcttcg
     5341 ctagttttac ttggcatttc ctatgtagct cgcttcttcg gtctactcat tgttcgtctg
     5401 gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc atgcgtaaat ggacaaaagg
     5461 atttctcatc tttggtgtgg tgactaccgt tatcggcttt atcctgcttt ttgtaggtat
     5521 ccaatctgac gggattaaga gcctactttc catgtccaaa gaacctgtct atgatagccg
     5581 tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta gaaattactc tccaccaaca
     5641 cacgctcacc atcacagact ctttcgatga tcaaatccac atttcttacc atccatctct
     5701 ttctgctcac catgatctta tcaccaatca gaacgataga actctgagtc tcactgataa
     5761 gaaactgtct gaaactccgt ttctctcttc tggaattggt gggattcttc atatcgcaag
     5821 tagctactct agtcgttttg aagaagttat tctccgacta ccaaaaggga gaactctaaa
     5881 agggatcaac atctcagcca atcgcggaca aaccaccatc ataaatgcta gccttgaaaa
     5941 tgcgaccctc aatacaaaca gctatatcct ccgaattgaa ggaagtcgta tcaaaaacag
     6001 taaactcaca acgcccaata tcgttaatat ctttgataca gttcttacag atagtcagct
     6061 agagtcaaca gagaatcact tccacgctga aaatatccaa gtccatggta aggttgaact
     6121 gactgccaaa gattatctca gaatcatcct agaccagaaa gaaagccaac gaattaactg
     6181 ggacatctca agcaactatg gttctatctt ccaattcaca agagaaaagc ctgaatcaag
     6241 aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc gatgtcaagg atcaactcat
     6301 tgcgagatct gatgataata ttgatctaat atccacacca agcagacgtt gacaaaaacg
     6361 cttacatctg ctactatgga agcatattta tctaactaaa aaggaggttc taccatgaaa
     6421 caagaatggt ttgaaagtaa tgattttgta aaaacaacaa gcaagaacaa gcctgaagag
     6481 caagctcaag aggttgcaga caaggctgaa gaaacgatag ccgatctcga tacaccaatt
     6541 ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg aagtcgaact ggaaagccag
     6601 caagaagaga aaattgaaac tcctgaaggc ggtgaagcga gaacagaaat agaagaaaag
     6661 aaggcatcta attctactga agaagagcca gacctttcta aagaaacaga aaaagtcact
     6721 atagctgaag agagccaaga agctcttcct cagcaaaaag caaccacgaa agagccactt
     6781 cttatcagta aatctttaga aagtccttat atccccgacc aagctccaaa atctagggat
     6841 aaatggaaag agcaagtgct tgatttttgg tcttggctag tggaagcgat caaatctcct
     6901 acaagtaagt tggaaacaag tatcacacac agttacacag cctttctctt gctcattctg
     6961 ttttctgcat cttccttttt ctttagtatc tatcacatca aacatgctta ctatggacat
     7021 atagcaagca ttaacagtcg cttccctgag cagctagctc ctttaactct tttttctatc
     7081 atctctatcc tagtagcgac aacactcttc ttcttttcat tcctcttggg tagtttcgtt
     7141 gtgagacgat ttatccacca ggaaaaggac tggacgctag acaaggttct ccaacaatat
     7201 agtcaactct tggcaattcc aatcttcctc actgctattg ctagtttctt tgctttcttt
     7261 gatagcctac gatttacggc cctcttgtgt gtgattagca ttggaatcat tctgcttgcc
     7321 agtctccata tcattacaag accaagtcaa gcaagtgaaa ccgactcctt ctatcaatta
     7381 ttcttgtctg tccttgtgaa cggagttatt atcctcctct tctttgtagc tgaagtggca
     7441 ctgattggag attatcttcg tatcttggcc tttctttaaa attcaatcct gtcatccttg
     7501 gcaggatttt ttctatgtca aaaaagcaag tcgattgacc tgcttctgct ttacttttct
     7561 tgtgctaatg ttttaaaatc tttgtctaat atgggttgca cttctatttg attggcgtct
     7621 agttggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagca
     7681 atggcttcat agtcttctgg tttagagcca tctcctgtga tttgaaccaa gtcaatctcc
     7741 cactgcactt ccttatccac caattgctca atataggctg caggaacaaa cggttctctc
     7801 ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt tccttctcca
     7861 tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc
     7921 gcttcaaact gagccaaacc atctgcctct aaaaagcttt tcaagttctc acgactaaag
     7981 aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag
     8041 gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca
     8101 gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtctct
     8161 gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata actgacctta
     8221 aaaagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc
     8281 tgacggagat agactacatc atagatatgt gactccaaac cgtctagcaa tgccaagatc
     8341 gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat
     8401 gttttcgcca taactggact cctttgaaat cgcttacata cagtatacct tatttttctg
     8461 aaagatacag aaacaaactt tagatttttg agtacaaagc atagaaaaac agcccctgag
     8521 gactgtttga tcttatacag tagctgcttg atccaagctt tcaccgatag cggctaggcg
     8581 ctcgatcact tcagcttgtg tcaattcatt ttttgaaaca tagcggttac gtgggtgaac
     8641 acggcactcg tgtgagcatc cacgaaggta cttgtcttca ttttcttctg atgtcaagat
     8701 acgacggtta cagaagggat ttccacagtt gacataacgt tcacatggtg ttccatcaaa
     8761 ccagtctttc cctacgatgg ttgggttgac atggttgaca tcaacggcga tacgctcgtc
     8821 aaatacgtac atttttccat cccaaagctc accttgaact tctgggtctt taccgtaagt
     8881 tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct tcacggacca tccagcctga
     8941 gaatttctca cagcgaacgc cacctgtaca gtaaaccacg acacgcttgt ccatgaattt
     9001 ttccttgtta tcacggaccc attgtggtaa ctcacggaag ttgcgaatat ctgggcgaat
     9061 agctccacgg aaatgtccta ggtcgtactc ataatcgtta cgtgtgtcaa ggacaacggt
     9121 atctttatca agaagcgctt ctttgaactc ttttggagac aagtaagcac ctgttgtttc
     9181 aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa ccaaggtgga caatttcttt
     9241 cttgtagcga acaaacatct tcttgaaggc ttgttcattt tcttcgtcaa tcttgaacca
     9301 gagttcttcc attcctggaa ggctgtgaac gtagtccatg tatttttgag ttgtttcata
     9361 gtcacctgaa actgttccgt taattccctc gtcagcgact aggatacggc ctttaagacc
     9421 gattgattta cagaaagcca agtggtctgc agcaaattgc tctgcatttt caattggagt
     9481 ataaaggtag taaagtaaga cacgaatatc ttttgccata agatttgttc tcttttctat
     9541 tcttaaattt tctaaatttt ttatttatcc atactagtat acctgcttga gaaaacgaat
     9601 gcaatttatt tgactggaaa ttgtagagga ttctcgaaat ttcctgaatg gttaaaataa
     9661 ggacaagaga aaacatggat atctatatcc ttgtgccaaa aaaaccactg ccctccccag
     9721 accaacctga ggaaagcagt gattcttatt ttaggagtta ggaatgaata cacgaaatca
     9781 atttagctga ttattttttg tttttcaaga attcatcgta ttgtttttgc atttcgttca
     9841 atactttttc gtaggcacct tcagatttca atttttccat caattctgga atcgctttat
     9901 ctgggtctac agtaccagtg ttgatagctg tatcaaattg ttgcattgtg ttagcaatag
     9961 ctgagatttc agatttcaca ttgtcagtat tgaagataaa tccaagcgct ggagattctt
    10021 tagcttctgc caattctttc ttagaatttt cgatttgttg gtctgtaacg ttttcgttga
    10081 tgtaaaggat ccagttgtta ccagtgttcc atccacccat gtgagtgttt cctttgtagc
    10141 catcaagaac gcgaacacgg ttttctttac cttcaatttt ttcccagttc ttgccttctg
    10201 gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt caagaggttc aagatttcca
    10261 ttgatttttc tttgttctta gagttgtttg agatgacaaa gttagcaact tgtgttgttt
    10321 ggtttttctt gatgaagtta gtgattggtt tgatttggat atctttgttg gcaacacgtg
    10381 aaagcaagct gttaccgtag tcagctggtc ctactgtttc ttcacgaacg aaccaagtat
    10441 cttgttgaag gtcaaatgaa gtatcgcttg ttgcgacgtc ttttggaatg tagccagctt
    10501 catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg aggcacttcg taacggttta
    10561 caactttagt agtatcgcct tcaaggtcaa taacgaatgg aagcccgttt gctactgggt
    10621 agtcaaaatt atcagatggg atgaaaactt taccaatagc aaatggtact acgtctggag
    10681 ctttttcttt gatttgtttc aagactggct caagagtttc gtaagaagta acacctgaaa
    10741 tatcgatacc atatttggca aggagagttc cgttgaaggc aaagttttga gatgatgcta
    10801 cgttggctgc aactggtaca gcataaatct taccatttac agtattaccc ttgatataag
    10861 ctggatcaag tgccttgtaa aggtctttac cttctttttt gtacaattct gtcaagtcag
    10921 cataagcacc tttttgagca tttacaatat agttatctgc aaaggcgata tcatagtttt
    10981 caccagatga tgtgataact gacattttct taccatagtc accccagcca aggtattgga
    11041 tatccaattt ggcaccaact ttttcttcga tgattttgtt ggcatttgct aacaattcat
    11101 ccaagttatc tggtttgtca ccgatttggt acattttgat aacaggtttg tcacctgaat
    11161 cagcagcttt tttgctgtta cctgtcaaat ttccacaagc agcaagacct gcagccagag
    11221 cgactacact agcagatgca aaagcatatt ttttccagtt tttcatgata aaaactcctt
    11281 tttttatttt taaacttata aacaatgtaa tgatcttaac ttcacacaag ggaagttggg
    11341 aactgagaaa tgttcttttt caataagcac tattctttca caccaccgat agtcaaacct
    11401 tttacaaagt agcgttggaa gaatggatac aaaatcgcga ttggaagggt tgctaccaca
    11461 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    11521 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    11581 tacaagttat cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    11641 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    11701 aaaatccgag cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    11761 gtcttcttga aaaaagaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    11821 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    11881 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    11941 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    12001 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    12061 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    12121 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    12181 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    12241 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    12301 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    12361 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    12421 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    12481 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    12541 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    12601 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    12661 tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc aaatacctag
    12721 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    12781 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    12841 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt gaaaaatctt
    12901 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    12961 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    13021 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    13081 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    13141 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    13201 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    13261 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    13321 tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    13381 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    13441 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    13501 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    13561 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    13621 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    13681 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    13741 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    13801 atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa gctttcttag cctctgccaa
    13861 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    13921 ttctaaagtt tgagtctgct tactaatact agactaaaat caaaaagcat tatataacag
    13981 tgatatgaaa tcaactaaag aagaaatcca aac
//
LOCUS       DAVBED010000056        13366 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBED010000056 DAVBED010000000
VERSION     DAVBED010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.056"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..1222)
                     /locus_tag="VQ547_001737"
     CDS             complement(<1..1222)
                     /locus_tag="VQ547_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2543550.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSAS"
     gene            complement(1220..1333)
                     /locus_tag="VQ547_001738"
                     /pseudo
     CDS             complement(1220..1333)
                     /locus_tag="VQ547_001738"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1571..2032)
                     /locus_tag="VQ547_001739"
     CDS             complement(1571..2032)
                     /locus_tag="VQ547_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543551.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(1999..2142)
                     /locus_tag="VQ547_001740"
     CDS             complement(1999..2142)
                     /locus_tag="VQ547_001740"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2543552.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            2411..2791
                     /locus_tag="VQ547_001741"
     CDS             2411..2791
                     /locus_tag="VQ547_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2543553.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            2890..3111
                     /locus_tag="VQ547_001742"
     CDS             2890..3111
                     /locus_tag="VQ547_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2543554.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3128..3442
                     /gene="trxA"
                     /locus_tag="VQ547_001743"
     CDS             3128..3442
                     /gene="trxA"
                     /locus_tag="VQ547_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2543555.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3749..4282
                     /gene="queF"
                     /locus_tag="VQ547_001744"
     CDS             3749..4282
                     /gene="queF"
                     /locus_tag="VQ547_001744"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2543556.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4536..5204)
                     /locus_tag="VQ547_001745"
     CDS             complement(4536..5204)
                     /locus_tag="VQ547_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2543557.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5315..5869)
                     /locus_tag="VQ547_001746"
     CDS             complement(5315..5869)
                     /locus_tag="VQ547_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2543558.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(6115..7911)
                     /gene="pepF"
                     /locus_tag="VQ547_001747"
     CDS             complement(6115..7911)
                     /gene="pepF"
                     /locus_tag="VQ547_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2543559.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(7922..8665)
                     /locus_tag="VQ547_001748"
     CDS             complement(7922..8665)
                     /locus_tag="VQ547_001748"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2543560.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(8667..9617)
                     /locus_tag="VQ547_001749"
     CDS             complement(8667..9617)
                     /locus_tag="VQ547_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2543561.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(9755..10183)
                     /locus_tag="VQ547_001750"
     CDS             complement(9755..10183)
                     /locus_tag="VQ547_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2543562.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10164..11252)
                     /locus_tag="VQ547_001751"
     CDS             complement(10164..11252)
                     /locus_tag="VQ547_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2543563.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(11271..11741)
                     /locus_tag="VQ547_001752"
     CDS             complement(11271..11741)
                     /locus_tag="VQ547_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2543564.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(12032..12484)
                     /locus_tag="VQ547_001753"
     CDS             complement(12032..12484)
                     /locus_tag="VQ547_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2543565.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12521..12700)
                     /locus_tag="VQ547_001754"
     CDS             complement(12521..12700)
                     /locus_tag="VQ547_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2543566.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(12837..13016)
                     /locus_tag="VQ547_001755"
     CDS             complement(12837..13016)
                     /locus_tag="VQ547_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543567.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13181..>13366)
                     /locus_tag="VQ547_001756"
     CDS             complement(13181..>13366)
                     /locus_tag="VQ547_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543568.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         3995 a         3044 c         2405 g         3922 t
ORIGIN      
        1 gactagcact tactgagagt gacttagact gtgaaagtga ctgactggtc gtgctagatt
       61 caactacctt tcctctaccc ttgaagtagt tagttctaat gttatctgtt ttagcagcgt
      121 aaggggtaaa tgtaaaggat gtatccgttc cagtaattgg tacagtccaa gatgatgtta
      181 atccatatcc ttgcttagca aagaaaccat tcatttgggc accatttccc caagtatacc
      241 cactacccca cgtcgtcatt gtagatgtat tataggatcg aaccagtaca ccatctttgt
      301 cagtaatgta gttctttaca tctgaagggg taccaagatc actgccaagg gttaacattg
      361 tttgtattga agtacctgta ttatagatag aatacccatg acccatcttt gaaagattac
      421 caagagccct tgtggtagga tctacatacg taaccgtata ggtaaaggtc agttttgaac
      481 catcatttgt cactgtcaat ttatagtaaa ttggaacatg atataccgaa tctaaacctg
      541 tacctgtata aacttttgtc tcacttttag caatgtttag acttgcatta attgcagggg
      601 cgccatttac aatcgtattg ccagaaaaaa cagcagcttt tatagaagcc agcaattgct
      661 cgatggaatc cactgaacgc ttgcgtcgct tagcataaga ttggagattg acatttgtaa
      721 ctgatgctgc ataatcacta gctggtttct tacgatcttc ttcgaccttc ttagcagttg
      781 cttctgtagc ggcagctgtt tgtgatccta ccacagtaga tgatgcagag atacttgtcg
      841 aagccgatgt acttgctgat tctgatgcac ttgtactcgc tgaggtcgaa gcgctggttg
      901 aggctgactc agatgcagat gtacttgccg actctgaagc tgacaaacta gttgaactcg
      961 ctgaattact tgtagatatc gtacctagaa ctactgtatc atttgttgcc aaagcatccg
     1021 ttttctctac agttttttca agtactgccg actcatttgt aaataccttc gtttgagttg
     1081 caacggttcc acttatgaca gttcccgcag caactattcc cttgaggata tcaagcccag
     1141 taattgaatg acttacttta tcttctaccg tttcggtcat gacctgagta gtatcaacac
     1201 caccacgcat gaccttaaac aagccaaaaa gagaagtcga ggcccgtagc caatgcttcc
     1261 ctgatttgat taatttgaac cgagttactc ggtctgtttc tctatattca cccttctgac
     1321 gtctaaaaaa tattttgaaa tttcctttcg agtattattt tcatgtatgg atataaataa
     1381 attaccatac tataattata gaatagggaa cccaaaatag caagaaactt gaggtatttt
     1441 tgctaaaaaa aaaaagcatt ttactatttt atatatatat tataagataa gttttttata
     1501 aagacacgca aatgagtata aatcagctaa tttttggttt atattcctat ttttatgcat
     1561 aattattctt tcattctcta atttgtgaat caatatatct gattagaaaa ctaccattga
     1621 gtttttgctc cacctcatta gtccgctcaa aacgccgtcc gctaatcttg tcatagactt
     1681 tctcccctct aggagcccct gcataaggac gatagaggta gcggttgatt cccgtttcgt
     1741 caatatatag gactggtaaa tcttttaggt tatccaaaat atcaagaaac tcagaaactt
     1801 tctcaggctt ttgttcccta aaactggtcg tcttttttaa aatgacctta atctgcttta
     1861 aaactgccca tacggagggc aaagcacaat caaaacgggc cgcaatttcc cgtaaaaaag
     1921 cgtctggatg agcctctaca aaggctttca attcttctaa agggatctta cgctttttga
     1981 cgactcgctt tttccgctct aagttccctt gtttacgtct ttcttttccc acgtgaagag
     2041 agttctgacg ccaacaccaa aaaacttggc tgcctcgaca tgactgtgcc cctctttgat
     2101 ggaatctaat gctccttgtt taaaatcagt actatatgcc atagctttat tagaccatgc
     2161 ttattttaaa ctaagcaact atagatagag aaatgaaata aaatctaaat tcgaatgtga
     2221 taaggagtta gaaattgaaa caataggatt cccccattat tcacacaaaa ataaaaccac
     2281 taaaaaacag agcttgccag cattcttgaa aagtagtata attattgcat gcgcaatcat
     2341 cttgtgacgc agagactgcc cgttaatgga ctttcttcta tattatgact ctaaaaagaa
     2401 aggagacact atgacctatt tggaaaaatg gtttgacttc aatcggcgtc agaaagaaat
     2461 tgaaagtctc ttggaagaga ccattgccca acagagcgag caaagtctga ccttgaaaga
     2521 gttctacctg ctctactatc tggacttggc tgaagaaaaa tctctacgcc agattgacct
     2581 gccagataaa cttcatctga gcccgagcgc agtttctagg atggtggctc gcttggaagc
     2641 taaaaattgc ggtctactca gtcgcatgtg ttgccatcaa gatagacgct ctagttttat
     2701 ctgcctgaca aatgatgggc aaaagacact ggcctcgcta caaaagactg tcgaagaaag
     2761 cttggaagca ggtttggatt tcttgattta agatgatttt aaaaaaagtt gcgtgcgcaa
     2821 tcatttttct tgacattctc ttttataagg agtaaaataa agttagcatt aaacaaagga
     2881 gttttaaata tgattgaaat tacctatata gatgccagca agaacgaaag aactgtgact
     2941 ttcgagtctt atgaagactt tgaacgttca caacaagctt gccttatcgg cgtcgcagac
     3001 tactaccctg tccaaaaatt aacttacaag ggtcataatt tggactacca tgggacttat
     3061 ggagatatct tcttctatct catgaaacaa gatttaagcc aatataacta aaaaaaggag
     3121 aaatacaatg gcaaaagcaa ttacagatgc aacattcgaa caagaaacaa aagacggttt
     3181 ggtcttagta gacttctggg caacttggtg tggtccatgt cgtatgcaag gtccaatctt
     3241 ggacaaattg tctgaagaac tttcagaaga tgtcttgaaa atcgttaaaa tggacgttga
     3301 tgaaaatcca aacacagctc gtgcttttgg aatcatgtct attccaactc ttctcttcaa
     3361 aaaagacggc caagttgtca aacaagttgc aggtgttcac acagcagaac aaatcaaggc
     3421 catcattgct gaattgagct aatcaaacga gagaccaagt actttctttg gtctcttttt
     3481 tcttgccctt tgccattttt caaaaaatat gctagactat agtagattga aactagaata
     3541 gtacacctct acttctaaaa cattgttaaa aatcgatttg actgtcctga tcgatttgtc
     3601 ctgtttttat ttcattttac tatataagta gaatattacg atgtttggga tatgccatcg
     3661 ctaaaaaaaa actcgatttg gtatttttta gttccctaat gggagctttt tgcgtgctct
     3721 gaacatttcc cattttggaa ggagtactat gaaacatcaa tcagccttgg tcgtctttag
     3781 tggcggtcaa gattcaacaa cctgcctttt ctggaccatg caacactatg aaacagtcga
     3841 agctgtcacc tttgcctacg gccaacatca tcacctcgaa attcaaatta ctagagaaat
     3901 cgctaaggaa cagggcattc gtcaccatat cctcgatatg tctctgctgg gacaaatcac
     3961 tgctcagcca gactttgcga cgattcatat ttcctacatt cctgacaagc tctgtgtcga
     4021 gtcaaaatcc ctcaaactat atctatttag ctaccgaaac cacggagatt tccacgaaaa
     4081 ctgtatcaac accatcggga aagacttggt caacttgcta gaccctcgct atttagaagt
     4141 ctggggaaaa ttcactccgc gcggtggcat ttcaatcgac ccctactata actacggtaa
     4201 gcaaggaact aagtatgagg gcttggcaga acaacgcctc ttccaacacg acctttatcc
     4261 agagaaaatt gacaaccgct aaagtcatac tcaatgaaaa tcaaagagca aactaggaag
     4321 ttagccgcag gttactcaaa gcagtgtttg aggttgtaga taaaactgac gaagtcagat
     4381 caaaacactg ttttgaggtt gtggatagaa ctgacgtagt cagtaaccat acctacggca
     4441 aggtaaagct gacgtggttt gaagagattt tcgaagagta tcatacgaaa aagccctgtt
     4501 cctcaagatg aggagcaagg ctttttgagt ttcaattatt cttctgttcc aaggaaattt
     4561 tttgcaacaa gggctgcaag aactccacca gcgattggtg caaggatgaa aatccaaact
     4621 tgttgaaggg ctgcgccgcc taccaagaca gctggtgcca agctacgagc tgggtttact
     4681 gaaagtccag taatcttcaa tccgacaaga atcatcgcca tcaatgacaa accgattacc
     4741 aaaccagcaa tcgcgccatt gcccttgctt tctgaagtca cagtcatgat aaccaataca
     4801 aacaagaaag ttgcgatgac ttcaaacaag aaaccaccaa agacagtgac accgtttgcc
     4861 aaggcatttt caccaagact agcagttgac atacctgaat tactcaagag gaagaagact
     4921 gcgccagaag cgatgaaagc tccaacaacc tgaccaagga tgtagtttac aagttctgaa
     4981 gatgacaaac gtttgtttac aaacatagca atcgaaacag ccgggttcaa gtgagcacct
     5041 gaaacagttc cgattgagta ggctgccacc acgattgcca aaccaaaggc aaaggcgatt
     5101 ccaaggtgac caaggccatc aagaccattt ccaaaaacaa cagctcctgt tccaacgaac
     5161 acaagcatga acgtaccgat taactcagca acaaattttt tcattttctt tctccttttt
     5221 tcaaaaacta gatactagtc tatcaaaagt aggaaagggt ttcaagaaaa ttgattggaa
     5281 attttttgaa aatcatagaa ctattagcta atctctagta ttgaaaagac tggatagctt
     5341 ctttcaactc atcttgtaaa ctatttctct ggtcaagttg gacatagact tccaccagac
     5401 aggatctaaa gttggaaaat ttgtaaaaat cctccctttc ttctatcgga aaatcaacag
     5461 tttttatcca agaagctact tgttcttgcg ctaacttccc ttgtaaaata ggttcataga
     5521 tcactcttgc taaacgccaa tcctcatcat ctgtaaagcg aatcgacatt cttttaaata
     5581 attggccaag tatctcaaat acttcatgaa ctctgttttt aggaaagccc ggatgacaaa
     5641 ccacctctgt cagtaaatcg gctccatgtg caaaagcatg aacccaacca tactgacttg
     5701 aaaaacccct tgtatccttt tcttttgaaa gatagtgcaa gccttgattt aaaaggacat
     5761 tacgaatttc tggagaagga tttcccaaat gatcaaacaa ccactggatt tcttcctggt
     5821 tataatttgg tttttcttct gctatttttc ttagtaaatc ttgatacatg gtcaatacct
     5881 ctacatttct agcaactgtt caaaaaggca gtcttaaatg actcaatatt gaattctcaa
     5941 ttaaatacaa tctgatataa aatgacgtaa ataactatca ataccagttc tacagtaagt
     6001 tcaaatttaa catcacgatc ttcaacgaca tttttgaaaa tagctacaac taagacaaat
     6061 agaatgacgc ttaacaagcc cataaacatc attctaaaaa atttttctat tcccctactc
     6121 tcccaactca gcactatagg agataatctg gtcaactgtg tcagacaaga attggatggt
     6181 atcacggagt ggtttgtctg ttgaaatatc agcaccgata atcatggctg actcaagtgg
     6241 tgtcttgcta ccacctgatt tgaggagatt gagccagtct tcagctccag tttcagaatg
     6301 ttttagatga aggtaaccag cagtcgagat aactagtcct gctgagtaag tgtaactata
     6361 caagcccata tagtagtgag cttggcgcat ccaagtcaga gttgcatcat cgtcaatttc
     6421 aatagcatct ccccagaaat ccgtcaaaac ttccttcata atgctgttga gcttgcttgc
     6481 tccaaaggtc tccccttctt caatcaatgt atacacctta cgctggaagg cggcttccaa
     6541 gaggtgggtg ataaagttat ggaagtaggt gtctgtcaag cgatgagcca gagcgaagcg
     6601 tttttgacgt gggtcattag actggttctc caagtaatca ctgagtagca attcattgaa
     6661 ggttgacggt gcttcaacat agtaggtcga catatgggca ttgaagtaac tttgatgatt
     6721 gtctgaaaag atgaattgac cagaatgccc gatttcatga atcaaggtat agacatcgct
     6781 caaacggcct gtccagctca tgagtacata agggtgtacg cgatatgggt ccgccgcata
     6841 accaccggaa tccttgccac tgttagcagc aaagtccacc cagcgctctt cttggtaacg
     6901 agcaacttcc tgacaatatt cttgccccaa aggttctacc gacttcatga ccaaatcata
     6961 ggcatcgtca atagtcactt caggattcag ggcgctgtcc aagtccaatt tccagtctgc
     7021 aaaggtcatc ttttcaagac catttacctt ggcaacatgc ttgaggtatc tctgagcgac
     7081 tggtgcaaag tccttcatga tgaggtcaat ctggcggtca aacatgacac ggtccacttc
     7141 ttgttcagct agaagatagt caaagacaga gtcgtatccc ttcatatcag ccaagagttt
     7201 ttcagacttg acctgagcca gataggctgc tgcagccgta ttttggtgct tacgaagtcc
     7261 ctctgagaag gaacggaagg atttctcacg aacctcagca tcctcatggt tttggtagaa
     7321 attctcatag gtcacaaagc tgtttttgta ggtcttgcca tgggcttcaa agtcagccat
     7381 ttcaaaatcc ccagctcgca tcttagtata aatgtcctgc ggactgtaga aaacttcacc
     7441 gagatttgtc aaggccttct ccacatctgc ccctaagtag tgggcttttt tgattttagc
     7501 ctgacgaatg gcagctgtta aatgtggcaa tttacccaaa cgatccaaga cttcctcgtc
     7561 tgctgccacc aaggcatcgt caaaaaaggt caaggctacg ctggcatctg tttcaaattc
     7621 catcccagct tgagcaatat ttgcaaattc gtcattgcta tagtccgtcg tctgaggcat
     7681 aaaaccatag ttgccaatat ggctcatctg aatgtagatc tgttccaatt ccgcaaaggc
     7741 cttctcgaaa tcctcaaaag tgtgaagatt gcccttgtaa tcacggctaa actggttgat
     7801 gtcttcgcga gctttctcga ttgcacgcaa gaaatcctca cggtcttggt atagagctgt
     7861 taaatcccaa agttccttct ctggaaattc tgaacggtgt ttttgttcca ttttcttcct
     7921 cttatttctc taattctact aaaacactaa gggctgataa ggcgtaaagc ggtgctgttt
     7981 ctgctcttag aatgcgaggg ccaagtcctg ccaaaacagc tcccttagct tcaaaatttt
     8041 caatttccgc aggtgacaga ccaccttctg gaccaaagat aaagagcaat ttggctcctt
     8101 tctcgagtcc agtaactgct tttataagag cagcggcttc tccttctttg gccgcctctt
     8161 cataggctac taagatgcgg tcaaactggt caagttgggc tagaaagtct gctttattct
     8221 cgaaaagatg gatacttgga acaacattac gcttactttg ctctgctgct ccaagagcaa
     8281 ttttttctag tttttcaacc tttttaccca atttcttgcc atcccactta gcaacggacc
     8341 aatcggcagg gaaggcccaa atctggctgg cacctagttc cgtcaccttt tgagtgataa
     8401 actccaactt atctcccttg ggaaatccag atgcgatggt cacttggact ggtagttcca
     8461 cattgtcatt taattcttgg accaactcaa actgacgatt ttccatatcc agcacgcgcg
     8521 ccaagcgctt gatgccatca tcaaagacta aggtaacctc atcctcttct ttcaagcgca
     8581 taacctgaaa catatgcttg ctggtttccc tgtcctcgat ggtgacagga gagactgcac
     8641 tccccttgac aaaatactgt tgcatgctag cctccaatca cacctgaaat atccttggtc
     8701 ttcttgaaga cgcaggcatt ccattcccct tgaatcatat gggtttcaag gaaaaatcca
     8761 gctgactcag ccgactggcg caccatgtcc cacttgtcct tgataatgcc actcatgatg
     8821 aggtagcctt catcctttac caagcgataa gcatcctccg tcagatgaat gagaatatcc
     8881 gccaagatat tagccacgat gacatctgct tcaatctcaa ctcccttaag caagtctcct
     8941 gctgctacat ggatattttc cataccagtg ttgagctcaa tattttcctg agcgacacga
     9001 accgccacat catccaagtc ataggcgaaa atctccttgg cacctaggag tgagcttgca
     9061 atagaaagaa cccctgaacc agtccccaca tctagcaccg tttcgccacc acgaagaacc
     9121 tgttccaagg caaaaaggct catcttggta gttgggtggg ttccagtacc aaaagccatg
     9181 ccaggatcca gcttgataat tttttctccc gcagtcgcct catagtctgt ccaagaggga
     9241 acgatggtca aatcatgagt gatgcgagca ggttcatagt atttcttcca gttgtctgcc
     9301 cagtcttcct cagccaaggc agtcgtacct atttttaact ctcccaaatc cataaaatcc
     9361 gtcaattctg ctaagcgagc ctgcaagtcc gcctcaacca ctgtcatatc caccgtgtca
     9421 gggtagtagg ctgtcactac gatttcttct tgctgctcca cctctgggaa aatctcgcca
     9481 aaacgatcca catttcccat atagtccatg ctgtcttcaa tcgcgactcc ttgcgctccc
     9541 agctcaatca agagattgga aaccaactcc tctccctcac gcttcactgt aacttttaac
     9601 tcttgccatg tttccattat taagatacca agcccgtaaa acacaaaacc aaaataggaa
     9661 attctctgaa gacgcttgtg tctaagagaa gtttatcttt ttggcacagt gtttagggcg
     9721 ggttcagttt agaaatgtaa ctgaaccatc ctttctaatc acttactttt aaataatctt
     9781 ttaatctctc ttgcaactga ggcacaactt gactggaact aagaaattcc tcaacattca
     9841 tcagctgata gccctgtcct tcatctccga agatgatatt gtcaaattgt tcttgtctta
     9901 gctgaccaac cataaagacc gatttcttgc ctttaaaaat tacgctagga taaatcttgc
     9961 tccaaagcag acagtcttca tctaaatgaa ttcccagttc ctcataaact tcacgccgag
    10021 cgcattcaaa agggctttcg tccccttcac ggccaccacc tggcaactcc cacatgttgg
    10081 gacaagggat atcgtccttg tcatcacgca aaatcgtcag tagcttatcc ccacaaaaga
    10141 gggcaatctt gcaaccttgg aaatcagaaa tttctagttc catcttcagt tccttctaac
    10201 atttcctttt ccagctctgc taacaagttt tcataatagc gtttctcgtc cctcaacatt
    10261 cgactactat ccattttctg tctagcaatc ttgagagcct tacgagttcg atctacatct
    10321 ttcttcacct ttaattgata ccaggcttgt atcacttgaa gattggacag tttgagagac
    10381 agaaacgatt tgacctgtcg aatactagca tattgctccg cttgctcaaa atctccttcc
    10441 aacaaggcga tatgaagcag ggatagttgg gcaactgtct gcatcatcgg agtagttgtc
    10501 ctctcaagta atgcttgaaa ctgctgttta gctacttctt ccttcccttc caaaatggaa
    10561 acttcacctt gcatacctaa tacaccatcc gcaaaactcc ctcgtgcatc ctcaggaact
    10621 gcttgaacaa agtctttcaa atcatattct tgaggagcca gcaaagtttg agcagaatgt
    10681 ctcaatacca ggtaggcgta tttggtattt tcagggtgtt gtagtaattc ccaaattttt
    10741 gctccatcgg tgatgtcgac tggcaaaatg ttatttagga agaaagataa attaagaaaa
    10801 atccaagtcc ctgcaaaata ccagcttctt gtcaaaaatc caaacactat cgccaataat
    10861 atcaagccga gatgaaccat caagcctcct gaaagcatca ggatgattct ttgatcgctt
    10921 tcatcctctt ttaaaccaat gtattgagca ccaacatttt tcagaatggc tgttctacta
    10981 agatgaaacc tgcctgactt tttggtcaaa ataaaatgtc ctaatccaaa agccaccagc
    11041 cgatagcctg tcaagtagcc acaaaaagca tgacccagct catgaagaat aaagattaaa
    11101 tacatgctta gaagagcgaa ggcataacca aaagtaaagg ctaaaactgc ggaatacccc
    11161 aactctgcaa atgcgattgt tccacaagca aaagctagca taataaagac aacagctagc
    11221 acataaacca aataagtccc aattttcttc ataacacctc caaccaactc ctagtatctt
    11281 ggataaggat aaaattctcc ctcttccaag ccaacttttc cttcttcaaa gacttcttgg
    11341 ttccattcca tgacaaattc ctctgcttct gggtcttcca aaaagtccat gaggacatct
    11401 agcccaacct cagcagtatc tttaaggaaa agcacaaaat aagctaaaaa ttcacgggaa
    11461 aatccttttt taggcaggta aggaataaca gtcaaatagt cttcctcatt gactgttgac
    11521 ttagcaggat tgtagaaaag gaccgcttcc tcaaaaagaa tgtcatctga tgaaacctct
    11581 ccgtcttcat ccaccatctc cacacctgca gcattttgcg cttccaatag aaaactcact
    11641 tctaccgcat ggttgcgttt gtcccagcta atctcaaagt caaagggaaa gttcttgtcc
    11701 aactcttcct ctaaaacatc taaaaatccg tatgttgcca ttttgtcctc tttctatgcg
    11761 actctttaat cgccccgatt gctcggaaat atgctaaaat agatactacc atcttaccac
    11821 aaaattattt tatgtcctaa ttataccata ttacctcatt taaacccttg gtatcagtga
    11881 ttttcttaaa agtctgattt cttcatttct cataaaaatc aatataaaaa gccctcgaaa
    11941 gggctaataa atctataaaa tcaataggcg agtaactagc acaagtggac gtgctttttt
    12001 attgactatt accacgatac cacgcttaat cttaggcttg aactttctta tctgcaatag
    12061 cgtctgtcaa agtctgagaa aagttaagtc ccatttctcg tcccaactta tctgcccatt
    12121 ttggtatggt caaagtcttt ttaatgggtt cctgacttcc taggtattct gatacatcaa
    12181 cagataccat agaaataaaa gatttatcaa ggtcataggt tgacacgaaa tcttcatcat
    12241 ctttaaaagg atcattatca attaaagaca agctattgat atctgatggc tgaggtaact
    12301 ctccatcact ctctatcaaa tctgcaacag ttatccctag ccactccgac cccatagcca
    12361 aagcctcaga aatcccctct ccttgtgtag ctgagtattc aaaatctggg aaatggacaa
    12421 aataagtcgc ttctgttccg tctgtgtcgt cataataaaa taaagctgga tacgtaacta
    12481 acatttcact acctccatat caaaaagcag ggactgaatt ttacaaccca gcttgctttc
    12541 ctatccctct ttcagtgtac ttattcagct caccatgaag gattgtgata ggtctttccc
    12601 cttgcttctc gattttaata tgggagcctt taccgcctct agtctttatc caaccatggg
    12661 ccgtaaagag tttaaccatc tctttttgtg tcataggcat agcgctttta cctcctgaca
    12721 acaccattat aacacgtgtt acacgtattg taaaggagtg atacttatta ttctattata
    12781 cataaaagcc cctagatgtg gttctaaggg aaaccaattt attcagacct atttttctaa
    12841 tgagtagtaa aaactgcttc tttatcgagc aattcatcat ctgtatagtc aattgtaaaa
    12901 gtatctcgat ctaagacaga ttgaggcgga gttgaatgaa tcataggacc actgcgtact
    12961 ctatattttt tatctccaat ttttacaaac tgatactctt cgaaaatcaa attcaaacca
    13021 cgtcaacgtc gccttaccgt actcaagtac agcctgcggc tagtttccta gtttgctctt
    13081 tgattttcat tgagtatgat taactctcaa gtcttcgaaa tcaggatttt caacagttat
    13141 tacaaggagg cgatttacta cttcaaaaac atcaattatt ctatttttca tattttttca
    13201 acccattatt agaatgaact tcttggtaag caaaatcaag tttagattta atgttttcgt
    13261 acaaatctaa aatctctttt ggagtatctt cccggaagaa aagttttctt ttccctgaaa
    13321 taacttgatc actaagaatc caatgacgaa tttgttttgt aaaaat
//
LOCUS       DAVBED010000057        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBED010000057 DAVBED010000000
VERSION     DAVBED010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.057"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ547_001757"
     CDS             complement(251..433)
                     /locus_tag="VQ547_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543569.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ547_001758"
     CDS             complement(649..1881)
                     /locus_tag="VQ547_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2543570.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ547_001759"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ547_001759"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2543571.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ547_001760"
     CDS             complement(3048..4217)
                     /locus_tag="VQ547_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2543572.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ547_001761"
     CDS             complement(4403..5707)
                     /locus_tag="VQ547_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2543573.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ547_001762"
     CDS             complement(5824..6978)
                     /locus_tag="VQ547_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2543574.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ547_001763"
     CDS             complement(6975..7526)
                     /locus_tag="VQ547_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2543575.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ547_001764"
     CDS             complement(7519..8655)
                     /locus_tag="VQ547_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2543576.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ547_001765"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ547_001765"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2543577.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ547_001766"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ547_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2543578.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ547_001767"
     CDS             complement(10172..10903)
                     /locus_tag="VQ547_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2543579.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ547_001768"
     CDS             complement(10905..12350)
                     /locus_tag="VQ547_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2543580.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2433 c         1656 g         4247 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBED010000058        12554 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBED010000058 DAVBED010000000
VERSION     DAVBED010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.058"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQ547_001769"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQ547_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2543581.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQ547_001770"
     CDS             complement(1477..2085)
                     /locus_tag="VQ547_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2543582.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQ547_001771"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQ547_001771"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQ547_001772"
     CDS             2410..3021
                     /locus_tag="VQ547_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2543583.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            3738..4424
                     /locus_tag="VQ547_001773"
     CDS             3738..4424
                     /locus_tag="VQ547_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2543584.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            4425..5357
                     /locus_tag="VQ547_001774"
     CDS             4425..5357
                     /locus_tag="VQ547_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2543585.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            5368..6297
                     /locus_tag="VQ547_001775"
     CDS             5368..6297
                     /locus_tag="VQ547_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2543586.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            6311..7750
                     /locus_tag="VQ547_001776"
     CDS             6311..7750
                     /locus_tag="VQ547_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543587.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            7819..9396
                     /locus_tag="VQ547_001777"
     CDS             7819..9396
                     /locus_tag="VQ547_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2543588.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            9456..10916
                     /locus_tag="VQ547_001778"
     CDS             9456..10916
                     /locus_tag="VQ547_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2543589.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            10938..11393
                     /locus_tag="VQ547_001779"
     CDS             10938..11393
                     /locus_tag="VQ547_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2543590.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            11480..11885
                     /gene="cdd"
                     /locus_tag="VQ547_001780"
                     /pseudo
     CDS             11480..11885
                     /gene="cdd"
                     /locus_tag="VQ547_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            11898..12347
                     /locus_tag="VQ547_001781"
     CDS             11898..12347
                     /locus_tag="VQ547_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2543591.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         4477 a         1627 c         2312 g         4138 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa
     3421 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
     3481 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
     3541 ttagtgctag aataatagat tagaattata gtgtattgaa tctataacag tacgccttaa
     3601 atgctaaaat atttctataa attaatttaa ctttcctgat agggctgttc atatcttatt
     3661 tcaattcact atataaataa aattgtagta gatgttattg aattagtaaa aaaaataaaa
     3721 aaacggaggt tttctgaatg gaaactaaaa aaattaaaaa tttaaaaggt caaataattg
     3781 tttcctgcca agcgttagaa ggagagccac tttatactcc aaatggagga gtgatgccgt
     3841 tattagcaaa agccgccttt caagcaggcg ctaaaggtat tcgtgctaat tctgtccgcg
     3901 atatttcaga aataaaagaa gaagttgact taccaattat aggtatcata aaaagagatt
     3961 acgatggctt tgaacctttt atttcagcaa ctatgaaaga gattgatgaa ttagttagtg
     4021 aaggagtaga cattttagct ttggattgta ctaatcgttc aagaccaggt tatgataata
     4081 ttactgactt tattcatgat attaaagtca agtatccaaa ccaattatta atggctgcta
     4141 tttctacttt tgaagaaggg aaagtagctg ctgaatcggg agtagatttt gtgggtacga
     4201 cattatctgg ttatacacca tatagcccta aaaaagataa tcctgatttt gagttagttg
     4261 aaagattggt aaaagagctt gacgtaccag ttattgctga aggaagaata agtactccgg
     4321 aacaagctag aaaaatgtta gatttaggtg cttacgcagt ggttgttgga ggagctatca
     4381 ctcgtccttt ggaaatagcg aagaagttta ttgaggtagt ttagatgaat caagaaatat
     4441 taaaaaagag taagattcaa ttgacagttg aacatattca aaaatattgg attttatatt
     4501 taatgatgat tccagcaact gttctactaa ttttatttac gtatggacca atgtacggca
     4561 ttattatggc ctttcaagac tttactgtct tcaagggata tactggaagt ccatttgtcg
     4621 gtttaaaaca ttttcaaaga ttgttctcag atcctttgtt ttatagattg ttcaagaata
     4681 cgttcatggt aggggtttta gattttttat tctttttccc agctccgctt atttttgcac
     4741 tcatattaaa cgaagtcaga aaagtaagat ttaagagtgt agttcaatct attagttatc
     4801 ttcctcattt tattccccta gtggttatgg ttggtattat ttttgaacta tttggttcat
     4861 atggtattat taacagttta ctttcatcac ttggaatgga gccaataagt ttctttacaa
     4921 aatctgaatg gttcttgcct ctctacattg gttcaggagt atggaaaaca ataggttggg
     4981 gttctatcat ttatatggga gcattaacca atatagattc aactttatat gaagcagcag
     5041 atatggacgg ggctaataga tggcacaaaa tgtggcatgt aactctacca agtttaagac
     5101 ctacagtagt tactttgttt atactaaatg ctggtggtat catgcaagta ggatttgaaa
     5161 aggtattctt gatgtctagt cctgcaacat atgaagtatc tgatgtatta tctacttatg
     5221 tttatagaca aggtatttta aattctgatt tcagttactc agctgcagta ggattattta
     5281 ataacatagt agctttgtta tttgttttat tagctaataa gattgctaaa aaacttggcg
     5341 aagaaggaat tgtataaggg gggtaaaatg attttttcaa aaaatacaaa aaagagtaat
     5401 agagacaaag aaaccttcgt tgattatctc tttatattca ttttaataat aataacctta
     5461 cttatgttgt atccattatg gtgggtagtg atgacgtcac tttcagaacc agtttggcta
     5521 tctaaaaacg ttgttaaatt atttccctta aaaatagata ttactgcata taagtttatt
     5581 tttggggatt ctaaactatg gcaagcatat ggtaatagtg tattgtatgc tgcactatct
     5641 acaattgtta gtgttgcggt atgtagtatg tatgcctatc cacttacaat tcctgaaatt
     5701 aggggtaaaa aattctggaa tactcttatt ttgattccaa tgttctttag tggaggaatg
     5761 atcccgcttt atatacaagt tgcaaacctc ggtttattga atactgcttg ggctcttgtt
     5821 ttacctggtg ctgtttctac atattatata attttgttta gaacacagtt taaatcaatc
     5881 ccaatggagc ttcgtgagtc tgctagaatt gatggggcaa gtgaatttag aattttttgg
     5941 aatttagtat taccattatc aaaagttatt ttcatgatta tagcacttta ttgcatagtt
     6001 ggttcatgga atagttttac tcctccatta ctttatttga atgacgacac taagatgcct
     6061 ttatctattt atttgagaaa tttagtcgtt acaaatacaa ctgatactgc tgaattatca
     6121 ctttctgcag gtaatacata ttaccaacaa attgctgctc aaggtggagg tattggtatg
     6181 cgtattgcta ttaagatggg tactattgtt gttagtgtta ttccaattat gatgatttat
     6241 ccatttattc agaaacattt tgttaaggga atcctgctag gttctgtgaa aggttaataa
     6301 ggtaattatt ttgcaaaatt taaaaaaata tcttttatta gatagcggtt tagtagttgg
     6361 gtatacatta gaaaatgctc aattaaaatt aaataagcta aaaaaagata ctgaaaacaa
     6421 tccactattt ggtgaagagt attttgccga aaatcctaaa ttatgggaag ttcgttttga
     6481 taattcatat ccaaacgtta tctatgataa agaattgaaa ttatatagat gttggtatca
     6541 aacatttgtt agtgatgaag caagcgaaga gactccttta gcagaacgtg gagagaagga
     6601 atacattgtc aagtcatcta gaatgacagc actttgctat gctgaaagta aagatggagt
     6661 aaaatgggaa aaaccaaatc tcaatctagt aaaatttaaa ggttcaaaag ataataatat
     6721 tgttctgatg catgcacacg gtgcaggtat catgctagat gaacaggagt tggatcctaa
     6781 gaaacgatat aaattagttt caaaattaga attttctccg aatcttcatt acatggttgt
     6841 tgttttttca gaagacggta ttcattttga cgaacctatt ccatggaaaa aatggaatcc
     6901 tgcagcagat agtcataatt ttccatttag agatccaaaa actggtaaat acgctgttat
     6961 tacaagaacc tgggcaaata acgtacgtct aagtgcaatt actttcagtg atgattttat
     7021 taattggtca gaacctaaag aaatccttag gggagatgga tttgaagatc aaatttattc
     7081 tatgccagta atttcatacg cggatatcta tttaggtttt gcttcaatgt accatgaagg
     7141 cgacacttta aatgaaaact atgataaagt agacttagaa ttgaaattct ctgctaattt
     7201 ggaacaatgg gatagtgtat gtaagggcga ctatctcatt gaaaggggag gtggagtata
     7261 cccgcagaat gctgattttg atgctagttg tattttcacg gctgctccaa taattgaaga
     7321 tgataagatt tggttctact atatgggtgg aaatggtaat cacactggct tccgagaaag
     7381 ttcattagct agaggatata ttaagaaaga ccaatttgct tattatacta ataagagaga
     7441 aggaattcca gctaaaatat ctacagttag cttccaaact tacgatgatg aaatttatat
     7501 cttagctgat attcctgaaa atggttatat taaagttgcg gtaggtacta aatacggtaa
     7561 tgcttattca gatttcggtc aggaagatat ctctcttgtt caagtttccg atggtaagta
     7621 taagttggaa tttaataaaa aatctatctt agatttaggt aattctccag ttgcgttcaa
     7681 atttgaaatc gagaatgcaa aattgtatgg tattgaaggt agtattcagc aacactatct
     7741 caaatattaa ccagaataat tcgttaacaa ataatctcta tattagtgga gatagatata
     7801 taaaatggag gtcttattat ggtaaagctt aataaggtat taaaagggag tgttgcattc
     7861 ctgagtgcaa gtttattgct agcagcttgt ggcaataacg ctaattcaaa gcccgctgaa
     7921 aaaacagctg atggtaaaac gaaaatttcg tttctatcta catggcaaat taatgatgtt
     7981 cgtccgccta aagatgaaac acttgttggt caatggttag aagaacagct aggtattgat
     8041 attgatcttg taactattcc tggcgaggga gtaagttcta aagtaaattc tcttattact
     8101 agtaaccagt taccgactgt tttgttgaca acaggagata agagtgatat cgctggtatc
     8161 aacaaacttg gtaaacaggg tgcattctta gatttgtcac aacacatgga caaactacca
     8221 aactataaga agtaccttga aaaaaataat gcattagctc aaatagaaga tgatgaaaaa
     8281 catatttatg ctttcacaaa attctttact gatgagaata tcatgtatac tacaccaatt
     8341 ctgagaaaag acttacttgt tggttcagaa tttgaagatc tttcaaaaat taaaactgtt
     8401 gatgactata caaaagtttt gaaatatttg actgaaaaac aaggttctcc agcatttatt
     8461 caacgtaatg gctatgaagg cttcatgaag cgagttacac cattgtggaa tttaagccat
     8521 cgtacatact atgactatga atcagattca tataaacatc cagttgaaca acctcaattg
     8581 aaacaattcg ttgaatggtt gaaagaatta cgtaaagata acgtacttca ccctgactgg
     8641 gcagttatga aagatgaaac ttgggaaggt ctattggctt ctaacaaggg ttcattcact
     8701 gttgaccgta tgaatatcat tggagataat aactttgata aatcatttga ttggcagcca
     8761 cttgtttatc cagaaattaa tggaaaacgt tatttgcaac cgaaaacacc gtacatttct
     8821 gattcaggtt gggtaatcaa tgccaatgca ccaaaagaag aaattgataa agcgttagaa
     8881 ttctttaatt tcttatacgc tgatgaaaat caagaaaaac ttgctattgg atttgaaggt
     8941 aaaacattta cacgtgaaaa ccctaatact caagcaggta ttaaatggtt gattcaaatt
     9001 tacggtgaaa atgctggaaa tgataaagca gaactgctgt ttaaacatgg taaccaagca
     9061 tttactcgcg ttcaaactaa attagatatt gaggcacagc caggaacatt ccctaaagtt
     9121 atgtatgatc aagtagataa aattaagaaa gatttaggtg gttttagacc agatactccg
     9181 gttctttcct ttacaactga agaattagat gttttaacta aatctgaagc aggattaaat
     9241 actttctttg atgaaaatat tattaaattc attgaaggac aaagagatat gagtgagtgg
     9301 gattcattta tcaatgaagc taaatctaaa gacttggata aagttacaaa agtatataat
     9361 gatgcctaca aacgtgtcaa agatagaatg aaatagacta aatggtagct ctctggtttt
     9421 tcagagagct actactgcct gagggggagt aagctttgta tgatgtagta attataggtg
     9481 caggaagttc gggcgcattg gctgcaattg cttcggggcg tctagggtta aaaacttgtc
     9541 taatagagaa gggaagtaga attggtggag ttcctattaa tacactaatg gggtcatttg
     9601 ctaatctata ttttgatgat tctggtagag taaatgcaag taaaattgtt ggggaattaa
     9661 tagaacgtat tatcaaaaaa ggtggtactg tctttaactc tatggaagaa ttgatgaatg
     9721 taaatgattt ttatcagatt acaattccct atcaaccaga agtttatgaa tcggttttaa
     9781 ctgatatgtt gattgagtct aaagttgata ttttactaaa tgttgaagtt aataatatta
     9841 tttatgatag taaaaatatt aaaagtcttg aaattttaag taatcaggaa gttaaattga
     9901 ttgattctaa agtttttatt gatgctacag ggaatgcaac aattgcttct gctagtggag
     9961 ctgatgttta tgaaaaaaat tcttcttacg gttgtttaat gagagttgga ggagttgata
    10021 tctcaaagac tatagaacat attgaaaaaa caaagcagtg gaactatata gaaggatata
    10081 atcagtggtt agaagaagta ttagcaaatc gaaagtacag agccactgga gcagttttaa
    10141 aagatccagt ttcttatgat catgccccta tgctttcaaa agacgaccat tttatgaatg
    10201 atgaaaaatg gaattacatt aaagaaagat gggaaaaatt tagatttatt tacactttag
    10261 aagtatcact atttaggaat gaattaaaaa aagctgtaga atctggggat tttaattttg
    10321 aaatttatca tgatgataaa tctggagtca ctatgaatgg cgacggtata agctatggtt
    10381 catggggtca aaatgtagca ttaattaatg ttgcaaaagc atttggattc aatcccaaat
    10441 atatggaaga tgaatcacat gctaatattc tttctagaaa atataattta acatttttat
    10501 cttttcttaa aaaatatgta ccaggttttg aaaattcttt tatccttgat cagggaacta
    10561 gagctactaa cagatcatgt aggcacattg ataattcatc tatgatggac gaaattcttg
    10621 attttccaat gtatacattt aagactatgt atagctatca aactcctaaa gaaataacgt
    10681 acaaatcaat tgtaggtgga aaattgaata atttgtttgt aataggtaaa ggtgcttacc
    10741 aatccgaaag ttttagatca caaattagtt gtatgttaat ggggatatca tcagcagcag
    10801 cggcaaaaac tattattgaa gataaaagca atactctaaa cattaataga gatttgttta
    10861 aatcgaactt agatatatta tttacatggg agttttctaa ttggattact gattaacaaa
    10921 taataaggga atattaaatg aatgatacta ataaaaatca atactttgtt tatgaatttg
    10981 atactagctt tgtagaaatg tcttattctc agttttttga aggatattgt attctttttt
    11041 caaaagaacc ctatccttct ttatctgata tgccaatgga atttagaaaa gaatttttaa
    11101 tggaaatgag tatattaggt gatgcgatgc ttgaagtgtt aaatgcctat agaattaatt
    11161 atgatatctt aggaaattca acacctgtac ttcatgctca tttatttccg agatacatgt
    11221 gggaagagga agagagaaga aaaactgtag ttcatagata tgattcttca gtttttagca
    11281 atcctgagtt tgaatttact atagaaaagc atggaccaat tattaaaaaa ctgaggtctg
    11341 ctattgatag acattataga gagtatcaac aattattaga tgattcaaac tgaactccac
    11401 attttcgatt agatttaata ccttgtatat tacaactagg ttgtggatga tataattttt
    11461 tgaaaaatat attttaggaa tgacttataa agcaattata tcagaggcta ttaaatcaat
    11521 ggccaaagct tatgctcctt attctgattt taaggttgga gctgcgttag taactgaaga
    11581 taaaaaattt tttctggatg taatatagaa aatgctgctt tttctcctac ttgctgtgca
    11641 gaacgagtat ctttttataa agctgtattt aaaggagaac gttcgttttc aagaacatgt
    11701 attgtaggtg gaaaaaatgg tatcttatca tcttttatag caccttgcgg agtgtgtcgc
    11761 caggtaatga tagaatttgt aatcctgatt catttgaagt tatattggct agtgatgttg
    11821 atacttataa agtatataaa cttaaagaac tactaccagt tagttttaat caagaaaatt
    11881 tataacagga gggaactatg gaattagttg aatttaaaaa tggacatgtt aatacggttc
    11941 atgagcatat cgcaataacg aaagtaaaag agtttctaaa taatcatgat atattaaaag
    12001 ataaaggtgg catacataaa atttctactg atttctttta caatataatt gatatggaaa
    12061 ctacaactga agagaataga ccgtgggaaa gtcataagga atattatgat gtccattatc
    12121 tgttaaatgg agaagaaaca attttatata acttcttgtc tcaaatggaa ttgtctgaat
    12181 ataaagtaga tgatgattgg caacaaatga atgggacagc tttatttagt attaaattaa
    12241 agaaagatat gttacttttg ttggaaccaa acgatgcaca tagaacaggc ctattggttg
    12301 aagaaccact taatattaag aaagttgttt ttaaggtaaa aatttaactg aaagtacttt
    12361 cggggattaa gaattttaaa atatttaaga aattgtattc taaagttcta aaattataga
    12421 tatttaattt aaagcttgtt aaaatagaat agtaacactc atctgctttc aaaaagcatt
    12481 ctattccatc tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatgaca
    12541 tcttggagtt gatt
//
LOCUS       DAVBED010000059        12546 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBED010000059 DAVBED010000000
VERSION     DAVBED010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.059"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            232..486
                     /gene="blpM"
                     /locus_tag="VQ547_001782"
     CDS             232..486
                     /gene="blpM"
                     /locus_tag="VQ547_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2543592.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            502..705
                     /gene="blpN"
                     /locus_tag="VQ547_001783"
     CDS             502..705
                     /gene="blpN"
                     /locus_tag="VQ547_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2543593.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            949..1098
                     /gene="blpO"
                     /locus_tag="VQ547_001784"
     CDS             949..1098
                     /gene="blpO"
                     /locus_tag="VQ547_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2543594.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1202..1321
                     /locus_tag="VQ547_001785"
     CDS             1202..1321
                     /locus_tag="VQ547_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2543595.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2107..2505
                     /locus_tag="VQ547_001786"
     CDS             2107..2505
                     /locus_tag="VQ547_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2543596.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            2543..3232
                     /locus_tag="VQ547_001787"
     CDS             2543..3232
                     /locus_tag="VQ547_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543597.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3274..3522
                     /locus_tag="VQ547_001788"
     CDS             3274..3522
                     /locus_tag="VQ547_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543598.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            3552..4163
                     /locus_tag="VQ547_001789"
     CDS             3552..4163
                     /locus_tag="VQ547_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543599.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4324..5118
                     /locus_tag="VQ547_001790"
     CDS             4324..5118
                     /locus_tag="VQ547_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2543600.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5115..5750
                     /gene="trmB"
                     /locus_tag="VQ547_001791"
     CDS             5115..5750
                     /gene="trmB"
                     /locus_tag="VQ547_001791"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2543601.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5876..6355
                     /gene="rimP"
                     /locus_tag="VQ547_001792"
     CDS             5876..6355
                     /gene="rimP"
                     /locus_tag="VQ547_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2543602.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6399..7535
                     /gene="nusA"
                     /locus_tag="VQ547_001793"
     CDS             6399..7535
                     /gene="nusA"
                     /locus_tag="VQ547_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2543603.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7557..7850
                     /locus_tag="VQ547_001794"
     CDS             7557..7850
                     /locus_tag="VQ547_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2543604.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7843..8142
                     /locus_tag="VQ547_001795"
     CDS             7843..8142
                     /locus_tag="VQ547_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2543605.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8159..10951
                     /gene="infB"
                     /locus_tag="VQ547_001796"
     CDS             8159..10951
                     /gene="infB"
                     /locus_tag="VQ547_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2543606.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11202..11552
                     /gene="rbfA"
                     /locus_tag="VQ547_001797"
     CDS             11202..11552
                     /gene="rbfA"
                     /locus_tag="VQ547_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2543607.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(11612..12546)
                     /locus_tag="VQ547_001798"
                     /pseudo
     CDS             complement(11612..12546)
                     /locus_tag="VQ547_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3837 a         2186 c         2846 g         3677 t
ORIGIN      
        1 aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgagtg ctggtattat
       61 caatcatgaa ctaggattct agttttgcag gaagtctaat gtaatttttg caattcaaga
      121 cgtttcgatg actattcaag atctggatga aaaattttaa aaaacgatga tatactaaac
      181 ttgtcaaagt tacaacaaga caaaaattaa aaataaaaaa gagtatttgt catggataca
      241 aaaattatgg aacaatttca tgaaatggat ataactatgt tatctagtat tgaaggaggc
      301 aagaataatt ggcaaactaa tgtcttggaa ggtggtggtg ctgcttttgg tggctggggg
      361 ctagggacag ctatttgtgc tgcgagtggt gttggagcac catttatggg agcatgtgga
      421 tacataggag ctaaatttgg tgtggatctt tgggcaggag taacaggggc aacgggtgga
      481 ttttaataaa aggagacttg tatgaatact tattgtaata taaatgaaac aatgctgagt
      541 gaggtttatg gaggtaattc cggaggagca gctgtagttg ctgctttagg ttgtgcagcg
      601 ggtggagtga aatatgggag acttctagga ccatggggcg ctgcaatagg aggaattgga
      661 ggagcagtgg tttgtggata tttagcctat accgctacat cataaaaatg aaagctaaat
      721 tttatgaagg ctatattctt tattattctc ttcgcttttc aaacctatct tatttatcta
      781 tccataagta tctccgataa aaaacaaaag actattgaat taacatcatt gaattgtttt
      841 gtcatattat ttctaatcta tgataaatta atttttctct ttattgccta tgtttttttg
      901 ataattttta tattaaactt gttccgtaac tgaaaagtga tatactatat ggatacaaaa
      961 atgatgtcac aatttgcagt tatggataat gaaatgcttg cttgcgttga aggtggagat
     1021 attgattggg gaagaaaaat tagttgtgca gcaggggttg catatggcgc aattgatggg
     1081 tgtgcaacaa cggtttgaca tttctattgg gaccatttgc tataggaata ggtgtaactg
     1141 gtgctgcagg tggagctata cttggaggtg tagcctatgc agcaatatgt tggtggtaat
     1201 tatggatttt aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga
     1261 tgacttaatt agaaaaatat tttcaaaatc ttccaaaaag gatacggata gtactctcta
     1321 aaaaataaat ttctcccctg tatttgctag cttaatttac aggggagttt ctttaatatt
     1381 gtttcgcctg tcaaaatgat atgtgatagc aggatgaaaa gtctacaaac aagttggtat
     1441 caatacaata taaagaggaa agtatgtttt taatgcttac tttttaaatt ttttaacaat
     1501 tcaagatgtt tcgatgacaa ttcaagattt ggatgaaaaa ttttaaaaaa caatgatata
     1561 ctaaacttgt caaagttgca acgggtgctg ctacattatg ttaaaaatcg ctcttgattg
     1621 ataagctgga tttgttagga aaggagtaaa taattatgga taagaaaaag atagtttcga
     1681 ctataatatg tatagtattt cttgtagtgt cagtagataa tttttttaga gacttaaccc
     1741 cgttactgtt cattttaaat attattggcc tgtcttgctt ttcagtgcta acatacatta
     1801 acataaaaga gatactctta aatataagta aatgatgatt tggttagtcc tagaaccaat
     1861 caacttatgt ttatcggctt ggcagatttt atgtttgtca tttgtttgta tagaggtatt
     1921 tcagaaacag aattctatca acaactaatc gcttatatag gtgtattctc tgcttgttta
     1981 tcacgcttct gctcatgtgg ggcttgaagt attataaaaa gtagctttct atccttttct
     2041 gacaggatat ttgagtagaa ggctctatta aattgttagt gaaataaatg aatggaggta
     2101 tttaatatga aatacagatt attttttgtt attttcttga gtagtgtgtt ggatattctt
     2161 ttagggacat ttttacaaat ctctatcgta tctattgggt ggcttgttct ttacagtggt
     2221 ttgtttgaag taggagtttt ccttcttgct aataaagggg tggcggtaaa aatcaaggaa
     2281 gtagatattc gaaatcgctt taaatttatt tttggaaaaa ccttatggtt tcaaattctt
     2341 ttgctcatct ttttgataat caaactttat cttggtttgg atgcgaggtt gattttattc
     2401 tatggacata ttttcattgt ctttaatgcc ttaatgtatc tattatctag tagtcaggtt
     2461 agccttaaaa aaaaacaaac tgtcttctta atcttacagc agtagagtct gacaaggtga
     2521 ggtcatagta gggaggattt ctatgaaaaa gtatcaactt ctattcaaaa taagtgcagt
     2581 cttctcttac ttatttttcg tatttggtct ttctcagctg acgcttatcg tccaaaatta
     2641 ttggcaattt tcttcccaga ttggtaattt cgtctggatt caaaatatct tgagtttact
     2701 ttttattgga gtcatgattg tggttcttgt taagacaggc catggttatc tcttccgcat
     2761 tccaagaaaa aaatggcttt ggtattcgat tttgacagta ttagtggtag tgttccagat
     2821 ctcttttaac gttcagacag ctaaacatgt tcagtcaact gcggaaggtt gggctgtatt
     2881 gattggttat agtgggacta actttgcaga gctaggtatt tatatagccc tgttctttct
     2941 ggttccactg atggaagaat tgatttatag aggattactg caacatgctt tctttaagca
     3001 ttcgcgattt ggtcttgatt tgcttcttcc ttctatttta tttgctctcc ctcatttttc
     3061 aagcctgcct agtctgttag atatcttcgt ctttgcaaca gttggaatca tctttgctgg
     3121 tttgacccgc tataccaaga gcatttatcc atcctatgcg gtgcatgtga tcaataatat
     3181 tgtagcgacc ttcccgtttt tgctcacttt tctacatagg gtcttggggt aaaaaaacaa
     3241 aaggcttgct tttcagccat agaggaggtc atcatgtata aacacttatt tttcctagat
     3301 tccaaaactt tagatcggtt gacaccctat attctagtct tggcttctga caccattgct
     3361 tttaatgttt ttgtgctaac ctttgtatct gcggtggttt ttaatttcct aaattccatg
     3421 ctagctttaa tggctatatt cataggggct ggctatgtgg tcggattttg gttgctaaaa
     3481 tggtttgttt tggaaaggtt agagctaaag gatgacgcgt aggaagtctg tttggtgagg
     3541 aggatagttt tatggagttt tttgataaat ttcatgcctt gtgttttgga tttttagtac
     3601 taataattgt cattacagtt ccttatacga ttaaccatgg gggttttttt caaaatgaat
     3661 ctgcattgat tcttgtaagt cttcttgtaa cctcgctgag tgttgcttat gctagaaagt
     3721 ttgaaatgat ttcttttggg atgttaagca agaaacaact tttgcttttc attgcaatct
     3781 ttcttctaag tgtacttgag acgctggttt atattcattt cttcgctgtt tcttctggct
     3841 caggggtcca acacttggcg gaagtcagca gaggaatttc cctgtctttg attttgacta
     3901 cctcagtttt tggccccatc caggaggaac tcattttcag aggacttctt caaggtgcgg
     3961 tttttgacaa ttcttggtta gggcttgtgc taacttcctc tctcttttct ttcatgcatg
     4021 gaccttctaa tgtcccttcg tttatttttt atctacttgg gggtttgttg ctgggctttg
     4081 cttataaaaa gagtcaaaac ctatgggttt ctactctagt acacatgttt tacaacagtt
     4141 ggccactcct atattattta taaaaattat gaaaaggtaa gcagaagacg gtgcttacct
     4201 ttttcaagct ataatgatac ccaagccaat ccagaggctt ttctttgaga atcgggttag
     4261 agtggttgac gaataggcca aaaactagta gaatagtaag gaaactttat acggaggaaa
     4321 gaaatggatt tgggtgataa tgagctaaca ctgactccca tacctgggaa aagtggcaag
     4381 gcttatatgg gtagctatcc tgacgggaag cgcatctttg taaaaatgaa cacctctcca
     4441 atcctacctg gtctagctag agaacaaatt gctccacaat tattatggag tcgtcgtttg
     4501 gcagatgggc gtgatatgtg tgctcaagaa tggttgacag gcaagatatt gaccccctat
     4561 gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc acgtccgttg
     4621 atgacacaat tgagtcgttt gggctatgcc atggaaacac ctgtagattt actacagtct
     4681 tggcaggaaa cggctccaga tgctttgcgt aaaaatcatt ttatcagtga agtgatggct
     4741 gatttacgtc agactattcc aggatttaga gaggaccatg cgaccattgt ccatggagat
     4801 gtacgacata gtaattggat tgagacagat agtggcttga tttatttagt agattgggat
     4861 tcggttcgct tgaccgatcg catgtttgat gtggcccata tgctctgcca ttatatttca
     4921 gaacatcagt ggaaggaatg gttgacctac tacggttaca agtacaatca aacggtatta
     4981 agtaaattgt attggtatgg tcaattgtct tatttgagtc agatttccaa gtattatatg
     5041 aaccaagatt tagaaaatgt caatcgggag attcatggtt tgcgtcattt ccgagacaag
     5101 tatggaaaga gaagatgaga gttagaaatc gtaaaggggc aacagaatta ctagaggcaa
     5161 atccccagta tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg gacttgtttg
     5221 gcaatgataa tcccattcat gtggaagttg gaagtggaaa gggtgccttt gtttcaggta
     5281 tggccaagca aaaccctgac atcaactata tcgggattga tattcaaaag tctgttttga
     5341 gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa catcaagctc ttgtgggtag
     5401 atggttctga cttaactgac tattttgaag acggtgagat tgatcgcttg tatctgaact
     5461 tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg tttgacctac aagaccttct
     5521 tggatacctt caaacgtatc ttgcctgaaa atggagaaat tcatttcaag acggataacc
     5581 gtggcttgtt tgagtacagt ttagtgagct tttctcaata tggcatgaaa ctcaatggtg
     5641 tctggttaga tttgcatgcc agtgattttg aaggcaatgt catgacagaa tacgagcaaa
     5701 aattctcaaa caaggggcaa gttatctacc gagttgaggc agaattttaa gagatagcct
     5761 aaaattaggc tgtacaagtg cttttgcttt acataagttg gcaaacgtgc tatactgata
     5821 gtaagaatat gaaaagtgag gcggggaaat atcttcgcct cttgcttatg aggaggtgga
     5881 cgcaatcgca acaatcgtag aattagtcag agaagttgta gaacctgtca tagaagctcc
     5941 ttttgaactc gtggatatcg agtatggaaa gattggcagt gacatgattc tcagtatttt
     6001 tgtagataaa cccgaaggaa ttaccttgaa cgacacggca gacttgacag aaattatcag
     6061 tcctgtccta gacaccatca agccagatcc cttcccagaa caatatttcc tagaaattac
     6121 cagtccaggt ttggaacgcc ctttgaaaac caaggatgcc gtcgctggag cggttggaaa
     6181 atacatccat gtcgggctct accaagccat cgataagcaa aaggtctttg aaggaacctt
     6241 gttggccttc gaagaggacg agttgactat ggaatatatg gacaagacgc gtaagaaaac
     6301 cgtccaaatt ccatacagtt tagtatcaaa agcacgttta gcagttaaat tatagaaaaa
     6361 gaaaggatag cttttgagga ttcaaaagtg aagaaaacat gagtaaagaa atgctagagg
     6421 ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga agatatcatc gacgcagtag
     6481 tagagtcgct tcgttccgct tatcgcagac gctatggtca gtcagacagc gtagctattg
     6541 acttcaacga aaaaacaggt gactttacag tttatactgt ccgtgaagtt gttgatgaag
     6601 tatttgatag ccgtttggaa atcagcttga aagatgctct tgccattaat tcagcttatg
     6661 aacttggaga caaaatcaag tttgaagaag caccagctga gtttggtcgt gtagcagccc
     6721 agtctgccaa acaaaccatc atggaaaaaa tgcgcaagca aacacgtgcc atcacttaca
     6781 atacttacaa agaacatgag caagaaatca tgtctggtac agtagaacgc tttgacaacc
     6841 gctttatcta tgtcaacctt ggtagcatcg aagcccaatt gtcaaaacaa gaccaaattc
     6901 ctggagaagt ttttgcttct catgatcgta tcgaagttta tgtttacaag gttgaagaca
     6961 accctcgtgg tgtgaacgtc tttgttagcc gtagtcatcc agaaatgatc aaacgtttaa
     7021 tggagcaaga aattccagaa gtttatgatg gaactgttga aatcatgagc gtggctcgtg
     7081 aagcaggtga ccgtacgaag gttgctgttc gtagccacaa tccaaacgtg gatgctatcg
     7141 gtacaatcgt tggacgtggt ggtgctaata tcaagaagat tactagcaaa ttccacccag
     7201 ctcgttacga tgctaaaaat gaccgcatgg taccaatcga agaaaatatc gatgttatcg
     7261 agtgggtagc agatccagct gaatttatct acaatgccat cgctcctgct gaggttgacc
     7321 aagttatctt tgatgaaaac gacagcaaac gtgccttggt ggttgttcca gataacaagc
     7381 tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt ggcggctcac ttgactggtt
     7441 accgtatcga tatcaagtct gctagcgaat ttgaagccat ggaagacgct gcttcagtag
     7501 agttggaagt agaaaacgat actgtagaag aataaaagct gctagaggag ggaaagatga
     7561 aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa cgaagtcatt gataagcgtg
     7621 atttgctccg cattgtcaag aacaaggaag gacaagtctt tattgatcct acgggcaagg
     7681 ccaatggccg cggcgcttat atcaaactag acaatgcaga agccctagag gcgaaaaaga
     7741 agaaggtctt taaccgcagc tttagcatgg aagtggaaga aagcttttat gacgagttga
     7801 tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg acttgaataa gcaaaagata
     7861 agtaatctct tggggcttgc tcagcgagca gggcgcatca tatcgggtga agaattggtg
     7921 gtcaaggcca ttcaagacgg caaggccaag ttggtctttc tagctcatga tgctggaccc
     7981 aatctgacca agaagattca agataaaagt cattattatc aagtagaaat tgtaaccgtg
     8041 ttttcaacac tggaattaag catagcagtc gggaaatcga gaaaggtttt ggctgtaaca
     8101 gatgctggat ttacaaagaa aatgaggtct cttatggaat agaagaggag gacatgattt
     8161 gtctaagaaa agattgtacg aaatcgcaaa agaacttgga aaagaaagta aagaagttgt
     8221 agcgcgtgca aaagagttgg gcttggatgt gaaaagccac tcatcaagtg tggaagaagc
     8281 tgtcgctgca aaaattgctg ccagctttaa gcctgcagct gctccgaaag tagaagcaaa
     8341 acctgcagca ccaaaagtaa gtgcagaaaa gaaagccgaa aaatctgagc cagctaaacc
     8401 agctgtagct aaggaagagg caaaaccggc tgagccagtt gctccgaaaa cagaaaaagt
     8461 agcagtgaaa ccgcaaagtc gtaatttcaa ggctgagcgt gaagcccgtg ctaaagagca
     8521 ggcagaacga cgcaagcaaa ataagggcaa taaccgtgac caacaacaaa acggaaaccg
     8581 tcagaaaaac gacggccgta atggtggaaa acaaggtcaa agcaaccgcg acaatcgtcg
     8641 ctttaatgac caagctaaga agcagcaagg tcagcaaaaa cgtagaaatg agcgccgtca
     8701 gcaagaggat aaacgttcaa atcaagcggc tccacgtatt gactttaaag cccgtgcagc
     8761 agccctaaaa gcagagcaaa atgcagagta cgctcgttca agtgaggaac gcttcaagca
     8821 gtatcaggct gctaaagaag ccttggctca agctaacaaa cgcaaggaac cagaggaaat
     8881 ctttgaagaa gcggctaagt tagctgaaca agcacagcaa gttcaagcag tggttgaagt
     8941 cgtccctgag aaaaaagaac ctgcagtgga tacacgtcgt aaaaaacaag ctcgaccaga
     9001 caaaaatcgt gacgattatg atcatgaaga agatggtcct agaaaacaac aaaagaatcg
     9061 aagtagtcaa aatcaagtga gaaatcaaaa gaatagtaac tggaataaca acaaaaagaa
     9121 caaaaaaggc aataacaaga acaaccgtaa tcagactcca aaacctgtta cggagcgtaa
     9181 attccatgaa ttgccaacag aatttgaata tacagatggt atgaccgttg cggaaatcgc
     9241 aaaacgtatc aaacgtgaac cagctgaaat cgttaagaaa cttttcatga tgggtgtcat
     9301 ggccacacaa aaccaatcct tggatgggga aacaattgaa ctcctcatgg tggattacgg
     9361 tatcgaagcc aaacaaaagg ttgaagtgga taatgctgac atcgaacgtt tctttgtcga
     9421 agatggttat ctcaatgaag atgaattggt tgagcgtcca ccagttgtta ctatcatggg
     9481 acacgttgac cacggtaaaa caaccctttt ggatactctt cgtaactcac gtgttgcgac
     9541 aggtgaagca ggtggtatta ctcagcatat cggtgcctac caaatcgtgg aaaatggtaa
     9601 gaagattacc ttccttgata caccaggaca cgcggccttt acatcaatgc gtgcgcgtgg
     9661 tgcttctgtt accgatatta cgatcttggt cgtagcggca gatgacgggg ttatgcctca
     9721 gactattgaa gccatcaacc actcaaaagc agctaacgtt ccaatcatcg tagccattaa
     9781 caagattgat aaaccaggtg ctaacccaga acgcgttatc ggtgaattgg cagagcatgg
     9841 tgtgatgtca accgcttggg gtggagattc tgaatttgtt gaaatctcag ctaaattcaa
     9901 ccaaaatatc gaagaattgt tggaaacagt ccttcttgta gctgaaatcc aagaactcaa
     9961 ggcagaccca acagtgcgtg caatcggtac ggttatcgaa gcgcgcttgg ataaaggaaa
    10021 aggtgcggtc gcaacccttc ttgtacaaca aggtaccttg aatgttcaag acccaatcgt
    10081 tgtcggaaat accttcggtc gtgtccgtgc tatgaccaac gaccttggtc gtcgtgttaa
    10141 agttgctgga ccatcaacac cagtctctat cacaggtttg aacgaagcac cgatggcggg
    10201 tgaccacttt gccgtttacg aggatgaaaa atctgcgcgt gcagcaggtg aagagcgtgc
    10261 caaacgtgcc ctcatgaaac aacgtcaagc tacccaacgt gttagccttg aaaacctctt
    10321 tgataccctt aaagctgggg aactcaaatc tgttaatgtt atcatcaagg ctgatgtaca
    10381 aggttctgtt gaagcccttt ctgcctcact tcaaaagatt gacgtggaag gtgtcaaagt
    10441 gactatcgtc cactcagcgg tcggtgctat caacgaatca gacgtgaccc ttgccgaagc
    10501 ttcaaatgcc tttatcgttg gtttcaacgt acgccctaca ccacaagctc gtcaacaagc
    10561 agaagctgac gatgtggaaa tccgtcttca cagcattatc tacaaggtta tcgaagagat
    10621 ggaagaagct atgaaaggga tgcttgatcc agaatttgaa gaaaaagtta ttggtgaagc
    10681 ggttatccgt gaaaccttca aggtgtctaa agtgggaact atcggtggat ttatggttat
    10741 caacggtaag gttgcccgtg actctaaagt ccgtgttatc cgtgatggtg tcgttatcta
    10801 tgatggtgaa ctcgcaagct tgaaacacta taaagacgac gttaaggaag ttacaaacgg
    10861 ccgtgaaggt ggattgatga tcgacggcta caatgatatt aagatggatg atgtgattga
    10921 ggcgtatgtc atggaagaaa tcaagagata agattttttg ctcctttctt aggtggtgag
    10981 ggacgcaagc aaaccgatgg tttcattgct tatttttgag cctagggtct caaaaatccc
    11041 ctgtgatggg actgataaat cagttccatc actttcacca cggcgaaaga agcagatgac
    11101 ttcaaattga acttcgtttc aatttaaact gaaaatcaag aagtttaaaa tagctaggtc
    11161 tgctggccta gcttttggtt caaagtagag aaaggaatat catggcaaat catttccgta
    11221 cagatcgtgt gggcatggaa atcaagcgtg aagtcaatga gattttgcaa aagaaagtcc
    11281 gtgatccacg tgtccaaggt gtgaccatca cagatgttca gatgctgggt gacttgtctg
    11341 ttgccaaggt ttattacacc attttgagta accttgcttc ggataaccaa aaagcccaaa
    11401 tcgggcttga aaaagcaact ggtaccatca aacgtgaact tggtcgcaat ttgaaattgt
    11461 acaaaatccc agatttgacc ttcgtcaaag acgagtccat cgagtatgga aacaagattg
    11521 acgagatgct acgcaatctg gataagaact aaagaagagg ggttgcccct ctttttcggc
    11581 tctttgtcaa ctgtagtggg ttgaagaaaa gctaagctcg agaaaggaca aatttcgtcc
    11641 tttctttttt gatattcagg gcgataaaaa tccgtttttt gaagttttca aagttccgaa
    11701 aaccaaaggc attgcgcttg ataagtttga tgagattatt ggtcgcttcc agtttggcat
    11761 tagaatagtg tagttgaagg gcgttgacaa tcttttcttt atctttgagg aaggttttaa
    11821 agacagtctg aaaaatagga tgaacctgct taagattgtc ctcaataagt ccgaaaaatt
    11881 tctctggttc cttattctgg aagtgaaaaa gcaagagttg atagagttga tagtggtgtt
    11941 tcaagtcttc cgaataactc aaaagcttgt ttaaaatctc tttattggtt aagtgcatac
    12001 gaaaagtagg acgataaaaa cgtttatcac tcagtttacg gctatcctgt tgaatgagtt
    12061 tccagtagcg cttgatagcc ttgtattcat gggattttcg atgaaactga ttcatgattt
    12121 ggacacgcac acgactcata gcacggctaa gatgttgtac aatatgaaag cgatcaagaa
    12181 cgattttagc attcgggagt gaaacagtct gggagactgt ttcagcctga gcctagaaat
    12241 ttgaaagcga agctgtttag ccaagtcata gtaagggcta aacatatcca tagtaatgat
    12301 tttgacgcga catcggacgg ctctatcata tttaagaaag tgatttcgaa tgatagcttg
    12361 tgttcttccc tcaagaacag tgatgatatt gagattgtta aaatcttgcg caatgaagct
    12421 catctttccc tttgtaaaag catactcatc ccaagacata atctcaggaa gacgcgaaaa
    12481 atcatgctca aagtgaaagt cattgagctt gcgaatgaca gttgaagttg aaatggccag
    12541 ctgatg
//
LOCUS       DAVBED010000060        12493 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBED010000060 DAVBED010000000
VERSION     DAVBED010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.060"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            298..558
                     /locus_tag="VQ547_001799"
     CDS             298..558
                     /locus_tag="VQ547_001799"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2543608.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(662..1132)
                     /locus_tag="VQ547_001800"
     CDS             complement(662..1132)
                     /locus_tag="VQ547_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2543609.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1149..3422)
                     /locus_tag="VQ547_001801"
     CDS             complement(1149..3422)
                     /locus_tag="VQ547_001801"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2543610.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3769..6870
                     /locus_tag="VQ547_001802"
     CDS             3769..6870
                     /locus_tag="VQ547_001802"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2543611.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6952..7959
                     /gene="pfkA"
                     /locus_tag="VQ547_001803"
     CDS             6952..7959
                     /gene="pfkA"
                     /locus_tag="VQ547_001803"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2543612.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8016..9521
                     /gene="pyk"
                     /locus_tag="VQ547_001804"
     CDS             8016..9521
                     /gene="pyk"
                     /locus_tag="VQ547_001804"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2543613.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10253..10478)
                     /locus_tag="VQ547_001805"
                     /pseudo
     CDS             complement(10253..10478)
                     /locus_tag="VQ547_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11326..12198
                     /locus_tag="VQ547_001806"
     CDS             11326..12198
                     /locus_tag="VQ547_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2543614.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12211..12375
                     /locus_tag="VQ547_001807"
     CDS             12211..12375
                     /locus_tag="VQ547_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543615.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12344..12493)
                     /locus_tag="VQ547_001808"
                     /pseudo
     CDS             complement(12344..12493)
                     /locus_tag="VQ547_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3811 a         2175 c         2668 g         3839 t
ORIGIN      
        1 ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaat aaaataggct
       61 ccataatatc tatagtggat ttacccacta caaatattat agaacccttt tttattgaca
      121 gtatcaggat atctttttca aatttttggt ttgttagata atgaaaatgt ttctatcaat
      181 ctagatttag gattaataaa tcgtaaatgt aattataaag aaaaagataa gttaaaaaaa
      241 gatgtattag caagagttgg tctaactcat attcatctat aacaaaagat atatgaattg
      301 tctggcggtg aaacaaaacg tgttgcttta gcgaaaatca ttcttaaaaa tccaccatta
      361 atattcgcgg atgagttgac tgcatcactc gattcgacga cttcacaagg aattatgaaa
      421 ttgttattag gtatgaaaaa taaaaatcgt ctaatcatca ttgcaactca taatcccgat
      481 atttggaatc aagcagatga agttataaat ttaaatcaat tattacagtc aatatatatc
      541 ttctatattt taaagtaatt ttatctgaat ccgttaagag actattgtcc caggctcttt
      601 ctgatgttaa agactttcta ccaggttttt taaaagcata attgttagtt gtagtcattt
      661 attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag cacttttgag
      721 cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg gtagcgatag
      781 cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt ccaggaaggg
      841 tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct tccatgtaga
      901 gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa taagcgctat
      961 cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg gttgcctgag
     1021 ttacttgaat gtcgttctca gcaagaaggg tttgcaactc agcctgtgta tgaatcttgt
     1081 tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc ataataatgt
     1141 aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt caagtggtag
     1201 tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa acggagagtg
     1261 tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacgtc catccattca
     1321 tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt aaggtaacct
     1381 tttgtcacga ctctttgtgc ctctggtcta aatggcaatt cacagagatt ttccaacatg
     1441 tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg ttgtaggtat
     1501 ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt actggatttg
     1561 atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac aggaaggtta
     1621 atagtaatct gattagcttt cccttgatag agctctgtat tgaaggtttg gtatgtctta
     1681 ccatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc ttcttgacca
     1741 agtgagaagg tttcacagtt ttcttgccca ccgaagttat caagtgataa ccaagtctgt
     1801 ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc ctgtcctagt
     1861 aatttcttgg tcaataaggc atttatggac tcacggaagt caattgattg ccaattgttc
     1921 atgtaaacat gggcaccatt atggaaaaag agatgcttgt gtatatgagt aggaagagca
     1981 tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc atgagtaaag
     2041 acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg ccaaaactga
     2101 ttgtagtccc cagtttttcg gtctagttga gctttcactt tttctaagtc agcttggtga
     2161 gcttcattgc cacggatata gtcgctagcc aagagattac gagaataggt taactcagca
     2221 agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc gttttcacgg
     2281 tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa accatcgact
     2341 cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcccgt tgtagcaact
     2401 tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg
     2461 caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg gtagtctcca
     2521 ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag attggcaaag
     2581 cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt tagcttttcc
     2641 tcagcctctg ctataagctc agctttacct tggggttgga cgagatttag ttgaggtttc
     2701 tctagctcaa tcttgtgagg aagtttaacc tcaagctcgc cctccatctt gtagagagcc
     2761 ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat gatggcaggg
     2821 atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga tagccctttt
     2881 tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc ctggttagaa
     2941 aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg aataagacca
     3001 tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt gagtaactga
     3061 tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt acgaaaaacg
     3121 tcactatctt cgaagtcaac caaataagaa aagcctaaaa gttgaaaagc aacagtataa
     3181 aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc tgttttttta
     3241 tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt
     3301 aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa gccacatttt
     3361 tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg attaaaacgc
     3421 atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa gcagaaaggg
     3481 aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta aattcaatat
     3541 agagaacaga gtaacaataa gaataaatag atagggtata aaagttctag gagatttata
     3601 ttatatgctt tctgttttta tatacaatat agtataaata taaaaatgat gacaaaaata
     3661 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     3721 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     3781 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     3841 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     3901 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     3961 gaaatgacag tgtttgtaga tgatcaggga gtgaatttgc gctttttagc tctatctagt
     4021 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     4081 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     4141 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     4201 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     4261 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     4321 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagcgt
     4381 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     4441 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     4501 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     4561 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     4621 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     4681 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     4741 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     4801 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     4861 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     4921 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
     4981 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     5041 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     5101 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     5161 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     5221 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     5281 gagttgcttg ctgaaacaga aggtattcat ctgaaaattg aagaaatcga tttagaagac
     5341 aaagaaacat tagctttatt tgcctctggt aatacaaaag gtatctttca atttgagcaa
     5401 ccaggtgcca ttcgtctgct taagcgtgtg caaccagtct gttttgaaga tgtcgtcgcg
     5461 actacttctc taaatcgacc gggtgctagt gactatatca ataattttgt ggcaagaaag
     5521 catgggcagg aagaagtgac tgttctggat ccagtactgg aggatatttt ggctccaacc
     5581 tacggcataa tgctctatca ggagcaggtt atgcaggttg cccagcgact tgccggattt
     5641 agtcttggga aagccgatat tttgcgtcgg gctatgggga aaaaggatgc ctctgccatg
     5701 catgagatga gggcttcctt tattcaaggt tcattagaag ctggtcatac tgtggaaaaa
     5761 gcagagcagg tctttgatgt tatggagaag tttgcaggtt atggttttaa caggtcacac
     5821 gcctatgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     5881 attttttatc aggtcatgtt aaattcttcc aacagtgatt acttaataga tgcacttgaa
     5941 gcaggttttg aagtagcctc tctatccatc aacaccattc cctatcacga taaaattgcc
     6001 aacaaggcca tctatctagg tttgaaatcc attaaaggag tcagtaatga tttagctctc
     6061 tggattattg aaaatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     6121 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     6181 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     6241 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     6301 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     6361 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     6421 agctatgcta ttatcttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     6481 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt tacactcttc
     6541 tcagatttat atcgacaggt tggtcaggaa gtaagagaag gagcattcta ctatatcaaa
     6601 gggaaagtcc aatcacgtga cggtcgtctg caaatgattg cacaagaaat aagagaagca
     6661 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
     6721 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
     6781 accatcgttt ctccccatca ttttgtagct aaatctgatg aattagaggc gaaattgaat
     6841 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
     6901 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaccaa tatgaaacgt
     6961 attgctgttt tgactagtgg tggagacgcc cctggtatga acgctgccat ccgtgcagtt
     7021 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
     7081 atggttgccg gtgaaattca tcccctagat gcagcttcag taggggacat catttctcgt
     7141 ggtggtactt tccttcactc agctcgttac ccagagttcg ctcaacttga agggcaactt
     7201 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
     7261 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
     7321 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
     7381 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
     7441 tttgtaatcg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
     7501 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
     7561 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
     7621 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt
     7681 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
     7741 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
     7801 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
     7861 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc gcacaaagcc
     7921 gatattgagc tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga
     7981 ccaaaaaggt catatataaa ggagtcacaa aaatcatgaa caaacgtgta aagatcgttg
     8041 caactttggg tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag gacggatact
     8101 ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat tgctaaattg attgaagctg
     8161 gtgctaacac attccgattc aacttctcac acggcgacca ccaagaacaa ggtgagcgta
     8221 tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa agttggtttc cttcttgata
     8281 caaaaggacc tgaaatccgt acagaattgt tcgaaggtga agctaaagaa tattcataca
     8341 aaactggtga aaaaattcgt gttgcaacta aacaaggaat caaatcaact cgtgaagtga
     8401 ttgcgttgaa cgttgctggt gctcttgata tctatgatga tgttgaagtt ggtcgtcaag
     8461 ttttggttga cgatggtaaa cttggtcttc gtgtggttgc taaagatgat gcaactcgtg
     8521 aatttgaagt tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc
     8581 ctaacactaa aattcctttc ccagctcttg ctgaacgcga taacgacgat atccgtttcg
     8641 gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt acgtactgca aaagatgtga
     8701 acgaagttcg tgcaatctgt gaagaaactg gaaacggaca tgttcaatta ttcgctaaaa
     8761 tcgaaaacca acaaggtatc gataacttag acgaaatcat cgaagcagct gatggtatta
     8821 tgattgctcg tggtgatatg ggtatcgaag taccgttcga aatggttcca gtttatcaaa
     8881 aaatgattat caagaaagtc aatgctgcag gtaaagttgt tatcactgca acaaacatgc
     8941 ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg
     9001 ctgttatcga cggaactgac gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc
     9061 cactcgagtc agtaactaca atggctacaa tcgacaagaa tgctcaagct cttcttaatg
     9121 aatacggacg tcttgattca gattcatttg agcgtaactc taagacagaa gtaatggctt
     9181 ctgctgttaa agatgctact agctcaatgg atatcaaatt ggtcgtaact cttactaaga
     9241 caggtcatac tgcacgtttg atttctaaat accgtccaaa tgctgacatc ttagcattga
     9301 catttgacga attgacagaa cgtggcttga tgttgaactg gggtgttatc ccaatgttga
     9361 cagatgctcc atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag
     9421 caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag
     9481 ctgttcgcac aaacacaatg cgtatccgca cagtacgtta agaaaaatat aaaaacctat
     9541 catatccagc tttagagctt gtgtgatagg ctttttgtat agagggtaag aaataggcaa
     9601 aactttcata atggattgat actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct
     9661 taccgtatat atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga
     9721 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatg aaataagata
     9781 tgcacaaatt gattaggaaa ttcaaatgaa tttctacaaa tgttttagca atcgtaatgt
     9841 acttgtctag attcgatctg atatattttc gatttaatga tatggtattt aaaacctcca
     9901 aagtagcttg ctccattctt ttacttacgt gagtgtagat gttatttact gttttagcgt
     9961 ttttgtgttc cactctaacc attatagcat tcttctcagc tagtgtacta aggagtgtgt
    10021 gcctgaaaat atgggaacta aggggctggt ttatcggttt ctctagttta gtatttgcct
    10081 tttgcaaagt gatgttaaat gcctttctct aaatttacat atcactattg tttaacaaaa
    10141 tctaatctac tttaggtcac ttattctttt tttgaaatgt agaatgaact ttttcaaagt
    10201 ttttcgaatc ttttaaaatc tgtttgtttt atatcgccat tctccccctt ttttaattct
    10261 ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg tctaggtgga
    10321 tgtcggggta tttgggattg agttttttta aggtagcctt ggcggagttt cttgacatag
    10381 ttagcgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg ggtattcttg
    10441 ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac gacataagcg
    10501 attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg tcctgcatcg
    10561 agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt ctgtagtcgt
    10621 ccagtctgat gatttttacg atatttcgtt tttctgctca tacagttgcc tctcggcata
    10681 ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt ggatatcgct
    10741 aggagaatcc ttttgaactg gaggaaagag ggtatcaatc aagctactga atactttagc
    10801 taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat ttccaatggt
    10861 gtttttactt ataccaatct tagtacccaa ttcttattga gtccaaccat tactagtcta
    10921 tattgtttta tagttgattg agtttggaat agtacgctgt agctgctaaa acatttctag
    10981 gaattaattt gactttccta atagagttgt tcatatctta tttcaatcta ctatgttttt
    11041 cacctctaac aatcgcaatc tcttctttat ccatgaatga aatcgctttc tatttttgta
    11101 agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt cgtaaaaaat
    11161 ttgttgacag agcacgaaac gcctactata attaaatcaa gcttaaggaa ataacaaaaa
    11221 aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa tatctgtaaa
    11281 gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa gaaatcaaga
    11341 aaattagcca cattaggaat ctgttcagcc ttgtttttag gcttggctgc ttgtcaacaa
    11401 caacatgcta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa agttccatgg
    11461 aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa atctctctta
    11521 tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa tgactataat
    11581 accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca caccgaatac
    11641 gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt tgggaccaac
    11701 tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa gcttgaaaag
    11761 aatgaccaat tgcttttcct agataacgat gcgattgata aaggaaaggt ctttgattca
    11821 caagataagg aagagtttga tattctattt tcgagagttc caactgaggc aactacagat
    11881 gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt caatgaaaaa
    11941 gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct gtttgtaggc
    12001 catgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa attgactttc
    12061 gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa gtatttgggc
    12121 accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat ggataatgat
    12181 aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt tttatttcta
    12241 tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccacg caaaaatgaa
    12301 acatttattg gctatatcca aagatacgat attgatggga atggctatca atcattaccg
    12361 tgtcctcaga actgagagga gttcttgaaa ccgtaaaacc gctttgaaca agagttactt
    12421 caacccattg gctccgacgg agtaagttgc tttcgtgaat accaaaatca gccgcaattt
    12481 gttcataagt tcg
//
LOCUS       DAVBED010000061        11888 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBED010000061 DAVBED010000000
VERSION     DAVBED010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.061"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            175..2466
                     /gene="pcrA"
                     /locus_tag="VQ547_001809"
     CDS             175..2466
                     /gene="pcrA"
                     /locus_tag="VQ547_001809"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2543616.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2509..3189
                     /gene="radC"
                     /locus_tag="VQ547_001810"
     CDS             2509..3189
                     /gene="radC"
                     /locus_tag="VQ547_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2543617.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3186..3875)
                     /locus_tag="VQ547_001811"
     CDS             complement(3186..3875)
                     /locus_tag="VQ547_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2543618.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3893..4534)
                     /locus_tag="VQ547_001812"
     CDS             complement(3893..4534)
                     /locus_tag="VQ547_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2543619.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDEIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4617..4832)
                     /locus_tag="VQ547_001813"
     CDS             complement(4617..4832)
                     /locus_tag="VQ547_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2543620.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4840..5187)
                     /locus_tag="VQ547_001814"
     CDS             complement(4840..5187)
                     /locus_tag="VQ547_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2543621.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5192..6307)
                     /locus_tag="VQ547_001815"
     CDS             complement(5192..6307)
                     /locus_tag="VQ547_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2543622.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6317..7276)
                     /locus_tag="VQ547_001816"
     CDS             complement(6317..7276)
                     /locus_tag="VQ547_001816"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2543623.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7389..7958)
                     /locus_tag="VQ547_001817"
     CDS             complement(7389..7958)
                     /locus_tag="VQ547_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2543624.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8086..8757
                     /locus_tag="VQ547_001818"
     CDS             8086..8757
                     /locus_tag="VQ547_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2543625.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8741..9559
                     /locus_tag="VQ547_001819"
     CDS             8741..9559
                     /locus_tag="VQ547_001819"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2543626.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9556..10452
                     /locus_tag="VQ547_001820"
     CDS             9556..10452
                     /locus_tag="VQ547_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2543627.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10496..11470
                     /gene="pta"
                     /locus_tag="VQ547_001821"
     CDS             10496..11470
                     /gene="pta"
                     /locus_tag="VQ547_001821"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2543628.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3458 a         2274 c         2560 g         3596 t
ORIGIN      
        1 tgaggtattg agctagttta tgaaaaaatt gggtgaaaaa gtcgagtgtt ttagaaaccc
       61 acagtgtagt attctagttt caatccacta tattttgcta ctccccgtaa agtttctatt
      121 ttccctgatt tctgatataa tagaaatatt gacttcaaga gtaaggaaga gaagatgaac
      181 gcattattaa atggaatgaa tgaccgtcag gctgaggcgg tgcaaacgac agaaggtccc
      241 ttgctaatca tggcaggagc tggttctgga aagactcgtg ttttaaccca ccgtatcgct
      301 tatttgattg atgaaaagct ggtcaatcct tggaatatct tggccattac ctttaccaac
      361 aaggctgcgc gtgagatgaa agagcgtgct tatagcctca atccagctac tcaggactgt
      421 ctgattgcga ccttccactc catgtgtgtg cgtattttgc gtcgcgatgc ggaccatatt
      481 ggctacaatc gtaattttac aattgtggat cctggtgaac agcgaacgct catgaaacgt
      541 attctcaaac agttgaactt ggatcctaaa aaatggaatg aacgaactat tttggggacc
      601 atttccaatg ctaagaatga tttgattgat gatgttgctt atgctgctca agctggcgat
      661 atgtatacgc aaattgtggc ccagtgttat acaacctatc aaaaagaact tcgtcagtct
      721 gaatccgttg actttgatga tttgattatg ctgaccttgc gtctctttga tcaaaatcct
      781 gatgttttga cctactacca gcaaaaattc caatacatcc acgttgatga gtaccaagat
      841 accaaccacg ctcagtacca attggtcaaa ctcttggctt cccgttttaa aaatatctgt
      901 gtggttgggg atgcggacca gtctatctac ggttggcgtg gtgctgatat gcagaatatc
      961 ttggactttg aaaaggatta ccccaaagct aaggttgttt tgttggagga aaattaccgc
     1021 tcaaccaaaa ccattctcca agcggccaac gaggttatta aaaataataa aaatcgccgt
     1081 cctaaaaatc tctggactca aaacgctgat ggggagcaaa tcgtttacta tcgtgctgat
     1141 gatgagctgg atgaggctgt atttgtagcc agaaccatcg atgaacttag tcgcagtcaa
     1201 aacttccttc ataaggattt tgcagttctc tatcggacta atgcccagtc ccgtacaatt
     1261 gaggaagccc tgctcaagtc taacattcct tataccatgg ttggcggaac caaattctac
     1321 agccgtaagg aaattcgcga tattattgct tatctcaacc ttattgctaa tttgagtgac
     1381 aacattagtt ttgagcgtat tatcaacgag cctaaacgtg gaattggtct aggtacagtt
     1441 gagaaaatcc gtgattttgc aaatttgcaa aatatgtcta tgctggatgc ttctgctaat
     1501 attatgttgt ctggtatcaa gggtaaggca gcccaatcta tctgggattt tgccaatatg
     1561 atgcttgatt tgcgggagca gctagaccac ttaagcatta cagagttggt tgagtccgtc
     1621 ctagaaaaaa caggttatgt cgatattctt aacgcccaag cgactctaga aagcaaggca
     1681 agggttgaaa atatcgaaga gtttctttct gttacgaaga actttgatga caccactgat
     1741 gtgacagaag aggaaactgg tctggacaaa ctgagtcgtt tcttaaatga cttggctttg
     1801 attgccgaca cagattcagg tagtcaggag acatcagaag tgaccttgat gaccctgcat
     1861 gctgccaaag gtctcgaatt tccagttgtc tttttgattg ggatggaaga aaatgtcttt
     1921 ccacttagtc gtgcgactga agatccagat gaattagaag aagagcgccg tctagcctat
     1981 gtaggtatca cgcgtgcaga gaaaattctc tatctgacca atgccaactc acgcttgctt
     2041 tttggtcgta ccaattataa ccgtccgact cgttttatta acgaaatcag ttcagacttg
     2101 cttgagtatc aaggtctggc tcgtcctgca aatacaagct ttaaggcatc atatagcagt
     2161 ggtagtattt cctttggtca aggtatgagt ttggctcagg ctcttcaaga ccgtaaacgc
     2221 ggtgctgccc caaaatcgat ccagtcaagc ggtcttccat ttggtcaatt tacagctggc
     2281 gcaaaatcag catctagcga ggcaaattgg tccattggtg acattgctct ccacaagaaa
     2341 tggggagagg gaactgttct ggaagtttca ggtagcggtg ctaggcagga attgaaaatc
     2401 aatttcccag aagtaggttt gaaaaaactt ttagccagtg tggctccaat tgagaaaaaa
     2461 atctaatttt ccatccttct cacgaataat aaagtgagga ggatttttat gtacagtatt
     2521 tcattccaag aagattcact attaccaaga gaaaggctgg ccaaggaagg agttgaagcg
     2581 cttagtaacc aagagttgct agctatttta ctcaggacag gaacacgtca agctagcgtt
     2641 tttgaaattg cccaaaaagt cttgaacaat ctttcaagcc taacggattt gaaaaaaatg
     2701 accctgcagg aattgcagag tttgtctggt attgggcgtg ttaaggccat agaattacaa
     2761 gctatgattg aactggggca tcgtattcac aaacacgaga ctcttgaaat ggaaagtatt
     2821 ctcagcagtc aaaagttggc caagaagatg cagcaggaat taggggataa aaaacaagag
     2881 cacctggtgg cactctatct caatactcaa aatcaaatca tccatcagca gaccattttt
     2941 atcggttctg taactcgtag tatcgctgaa ccgcgagaga ttcttcacta tgcaatcaag
     3001 catatggcga cttctcttat cttggtccac aatcatcctt caggagcggt agcgcctagc
     3061 caaaatgatg atcatgtcac taaacttgtt aaagaagcct gcgaattgat ggggattgtt
     3121 ctcttggacc atttgattgt ctctcattct aattacttta gttatcgtga aaagacagat
     3181 ttaatctaaa gttcattaac gacatagtca aagagttttt tatctttggg acgattttca
     3241 aaaagaagtt ctggatgcca ttggacaccg agaaaggcga catcatccgt actcatgaca
     3301 gcctcaatga taccatcttt aggatcatga gccacaactt ttaaatttgg tgctaagtcc
     3361 ttgatgctct ggtggtggaa ggagttgata tgagagattt ctccatagat ttcttggaga
     3421 acggtatctg gttctgttac caagcgttga gttgtgtact caacagaaga atcctgccaa
     3481 tggtcttcga tatcttggta caaagttcca cccatggcaa cgttaaagag ttgggtacca
     3541 cggcagacag agaaaatggg ctttttctgt ttaatagctt ccttgatgag ggccagttcg
     3601 aagatatctc tttgaaggtt atagtcatcg ctatcaatgg ttttgggttc gccataaaat
     3661 tttggatcga cattttgccc acctgtcaag atgagcttgt caatcaaact gatatagtgg
     3721 caggccattt cttgatcacc aatcggtagg atgatgggaa tccctccagc atctttaacg
     3781 ccttcaacaa agccttttgc tgcgtagctc atcatgatgt catcatctgg atgagctttt
     3841 tcgtttcctg taatcccaat aactggtttt ttcataaaat gattttcgct ttctaatcct
     3901 cttttcgcat gaagtagagg agggtttgga gttcacttgt caaatcgaca tactgaacga
     3961 ccacgtcttt tggtaaatgc agatggactg gtgaaaaact gagaattcct ttcacaccag
     4021 catcaaccaa gagattagca acctcttgtg acttgacgct gggaacagtt aggatagcag
     4081 tcttcacatc agcatccttg attttatcct tgatctgaga aatcccgtaa atgggaatct
     4141 cgtcaggagt ttgggtaccg acttcaggat ggtcgtctag gtcaaaggcc atgataatct
     4201 tcatcttgtt acgttcgtgg aagcggtagt ggagaagggc atggcccata tttccaatac
     4261 caaccagcat gacattggta atagagttgt cattgagcaa atcggcaaaa aatgtcatta
     4321 gttttttgac atcatagcca aaaccacgac gaccaagttc accaaaatag gaaaaatcac
     4381 gacgtacggt cgctgaatca ataccgatag cctctgcaat ttgcttagag ttggcacgtt
     4441 caatcttttc tgcatgaaat ctcttaaaaa ttcgatagta gagagagagt ctttttgctg
     4501 tagcttttgg aatagcaaac tgtttatctt tcacaaaatc acaacctttc tattcttcta
     4561 ttttatagaa acattgtgaa aaaatcaaca aaaataagaa aaaactaaga aaaatcttag
     4621 ttttgatgta aaaaatctgc atgagataga aaacggtaga ggtctccgac cagaccctga
     4681 taaacttttt ggcccctaaa agtcagagaa gtcacataaa gtgtatctgg taaggttaca
     4741 catcctgaca aagtcaacat gagagcctca tgatcctcat acttgagagt acgctctaca
     4801 tgatagcagt ccttataggt cagttcaaac attttggctc tatctttccg attttgtaaa
     4861 gacaccacgt tctaccaagc tatccatgag gaagtagaat ttttcctgat gaatatggtg
     4921 gtcttctgat ttgaaaatat caactagacg aaggctaaac ttgtcagtga tattgatttt
     4981 agcccctgta agttccttgt taatgatgat tttgagttgg aagccttcac cgctgtttgg
     5041 cactttttcc aaaaggcgag tcagttcata gttaccaacc ttagtttcaa aaaaggtgtt
     5101 atctttgagg gtgaattttt taacagaagg gctaagagtg taatcgtaac gacaattttt
     5161 taactgaatg attttttcaa atgccatatg gctaacctcc gataatttct tttaaggttt
     5221 ttgcgagggt ttgtaggtct tcaacggtat tttgtggcga caaactgatg cgaagggatt
     5281 ccttcaagcg ttctgaattt gcgccataca tggcttcaag aacatggctg gattggacaa
     5341 cgcctgcagt acaggctgag ccagtagaga ttgaaattcc agctaaatct agccgaagga
     5401 gtaagaggtc atttttctga ccaggaaatc caatattgag aacataaggg agatgatgtt
     5461 ttcctctatt caagtaatac tgaatgccct ccagctctgc cagaaaggcg gtttctagat
     5521 tttgtacatg ttgaaaatgt tcttcttgtt tttctaggtc ttcttttagg gctgcaacca
     5581 tgcctacgat agcaggcaga ttttcagttc ctgcacgttt tttctgttcc tggtctccgc
     5641 catgtagata ggaatcaaag tccatgctag atgcgtagag aaaaccgatt cccttaggac
     5701 catggaattt gtgggcagaa gcagtgagaa aatcaatgcc caattcttct gaatgaattg
     5761 ggattttacc aatagcctga actgcatcaa catgataggc agcagggtgt tgcttgagta
     5821 tttggccaat ttcagcgatg ggcagtaggt ttcctgtctc attattggca aacatggtag
     5881 aaaccaaaat cgtatcgtca cgtaaagcct tttgaatttg ctgggctgtg atttcttgat
     5941 tttctggctg gataatggtt gcttcaaacc caaagtgttg aaccaagtaa tcaattgttt
     6001 caaggacagc atggtgctcg atggcagttg tgatgatatg ttttccttgt tcttggtgac
     6061 gaagacagta gccaatgatg gtagtattat tgccttcagt cccaccagaa gtgaaaaaga
     6121 tatgttgagg ttttgtcctt agtaactggg ctagttcctg acgggcttct cgcaagagtt
     6181 tgccagcttg acgaccatga ccatgaatac tagaaggatt tccgtgggtt tcttgcataa
     6241 ccttggtcat agctgaaata gcaactgctg acataggagt cgttgcagca ttgtccaaat
     6301 aaatcaaaga atcaccttat ttctttttat tgtaggcaaa gagtgggctg actggttttc
     6361 tttcgtgaat acggacgata gcatcaccaa ttaactcact agcagtgatg tagcatacat
     6421 ttttaggagt tttttctttt gttgctactg aatcagtcac aagaatttct ttaatattag
     6481 tattgtcaag aagctcagca gctccctcga cgaagagacc gtggctagaa acagcataaa
     6541 tttctgtagc tccttcacgt tcaacgattt tagaagcttc agagaaggta cgtcctgtat
     6601 ttaaaatatc atcaatcaag atagctttct taccttcaac atcaccaata atataacctt
     6661 cgttacgagt tgcatcgtct tgagggtagt cgataatggc gataggagca tcaagatatt
     6721 cagccaggct acgcgcacgt ttgacacctg aatttttagg gctaacgaca acaacatctg
     6781 aaccaagcaa tcctttatcg cagtaatgtt ttgcgaatag gggaacagtg aaaagattat
     6841 ccactggaat atcaaagaaa ccttgaacct gaacggcatg caaatcaaga gtcaggatac
     6901 gatcaactcc agccttaacc agcatattgg caactagttt tgctgtaagt ggctcacgag
     6961 gacaagcaat gcggtcttga cgtgcatagc caaaatatgg aaggacaacg ttgatactgt
     7021 gggcacttgc acgcacacaa gcatcgacca tgattaacaa ttccattagg tggttgttga
     7081 cagggaaact tgttgattgg atgatgtaaa catcataacc acggacactt tcttcgatat
     7141 ttacttggat ttctccgtct gaaaattgac gtgatgatag ttttccaagt gggacaccaa
     7201 cagcttgggc aattttttgt gcaatctctt ggttagagtt gagtgcgaaa agtttcatgt
     7261 tttttctatc tgacattata gaccgtcctc tgtaaacttt ataaatccta gttatattta
     7321 ccttacatat atgaactggg atttgtgtat ttttatcttt tctattttac caaaaaatgg
     7381 agattatttc agctattttt catacttttg acaaatcgaa ccaattttga aggagctttt
     7441 tggtaggaaa tctgattttt ctctaaaaat tgtcggaaat cctgtttgcc ttgctcatga
     7501 ttttccactt caagctccaa ttcgtaatct gttatatcaa agtatcggct ctgatccagt
     7561 gccatgagac caatagctgt tttcatttca tagcgaagcg ttgttagaca accaagaacc
     7621 tgccagttct tactttggat accatgtttc gccaattcat ccagtactag tccttgagga
     7681 agttcttcct tactcagata gtcctcagca tcttttagtt gcaatttttg gttgtattcc
     7741 atgtttccaa cactctgcgg gactttgagt gtcaactcag cccagtcttc aaaggttcga
     7801 atgcgcatag cgactttctt ttctcgcagt tcaaaatcag gcgtgtcgat gtagtaattt
     7861 gtttgaagaa caggagtgac acctgtgaac tggtctttta gacgattgta ttcatctttt
     7921 ttcaatagtg ttttcaattc aatttctaaa tgtttcattt ttcttacctt tttttatcgt
     7981 tgaaagcgga tttatggtat aataagcatt gtatttattg tatatgaatc tggagaaaaa
     8041 atcaaagata tttttgacgg ataatatgag aacaagggag aatatatgac cttagaatgg
     8101 gaagaatttc tagatcctta cattcaagct gttggtgagt taaagattaa acttcgtggt
     8161 attcgtaagc aatatcgtaa gcaaaataag cattctccaa ttgagtttgt gaccggtcga
     8221 gtcaagccaa ttgagagcat caaagaaaaa atggctcgtc gtggcattac ttatgcgacc
     8281 ttggaacacg atttgcagga tattgctggc ttacgtgtga tggttcagtt tgtagatgac
     8341 gtcaaggaag tagtggatat tttgcacaag cgtcaggata tgcgaatcat acaggagcga
     8401 gattacatta ctcatagaaa agcatcaggc tatcgttcct atcatgtggt agtagaatat
     8461 acggttgata ccatcaatgg agctaagact attttggcag aaattcaaat tcgtactttg
     8521 gccatgaatt tctgggcaac gatagaacat tctctcaact acaagtacca aggggatttc
     8581 ccagatgaga ttaagaagcg actggaaatt acagctagaa tcgcccatca gttggatgaa
     8641 gaaatgggtg aaattcgtga tgatatccaa gaagcccagg cactttttga tcctttgagt
     8701 agaaaattaa atgacggtgt aggaaacagt gacgatacag atgaagaata caggtaaacg
     8761 aattgatctg atagccaata gaaaaccgca gagtcaaagg gttttgtatg aattgcgaga
     8821 tcgtttgaag agaaatcagt ttatactcaa tgataccaat ccggatattg tcatttccat
     8881 tggcggggat ggtatgctct tgtcggcctt tcataagtac gaaaatcagc ttgacaaggt
     8941 ccgctttatc ggtcttcata ctggacattt gggcttctat acagattatc gtgattttga
     9001 gttggacaag ctagtgacta atttgcagct agatactggg gcaagggttt cttaccctgt
     9061 tctgaatgtg aaggtctttc ttgaaaatgg tgaagttaag attttcagag cactcaacga
     9121 agccagcatc cgcaggtctg atcgaaccat ggtggcagat attgtaataa atggtgttcc
     9181 ctttgaacgt tttcgtggag acgggctaac agtttcgaca ccgactggta gtactgccta
     9241 taacaagtct cttggcggtg ctgttttaca ccctaccatt gaagctttgc aattaacgga
     9301 aattgccagc cttaataatc gtgtttatcg aacactgggc tcttccatta ttgtgcctaa
     9361 gaaggataag attgaactta ttccaacaag aaacgattat catactattt cggttgacaa
     9421 tagcgtttat tctttccgta atattgagcg tattgagtat caaatcgacc atcataagat
     9481 tcactttgtc gcgactccta gccataccag tttctggaac cgtgttaagg atgcctttat
     9541 cggtgaggtg gatgaatgag gtttgaattt atcgcagatg aacatgtcaa ggttaagacc
     9601 tttttaaaaa agcacgaggt ttctaaggga ttgctggcta agattaagtt tcgaggtgga
     9661 gctattctgg tcaataatca accgcaaaat gcaacgtatc tattggacgt tggagactac
     9721 gttaccattg acattcccgc tgaggaaggc tttgaaacct tggaggctat tgagcatcca
     9781 ttagatattc tctatgagga tgaccacttt ctagtcttga ataaacccta tggagtggct
     9841 tctattccta gtgtcaatca ctctaacacc attgccaatt ttatcaaggg ttactatgtc
     9901 aagcaaaatt atgaaaatca gcaggttcac attgttacca gactagatag ggacacttct
     9961 ggcttgatgc tctttgccaa gcacggttat gcccatgcac gattagacaa gcagttgcag
    10021 aagaaatcta tcgagaaacg ctactttgct ttggttaagg gagatggaca tttggagcca
    10081 gaaggggaaa ttattgctcc gattgcgcgt gatgaagatt ccattattac cagacgagtg
    10141 gctaaaggcg gaaagtatgc ccatacttca tacaagattg tagcttctta tggaaatatt
    10201 cacttggtct atattcacct gcacactggt cgaacccatc aaatccgagt ccatttttct
    10261 catatcggtt ttcctttgct gggagatgat ttgtatggtg gtagtctgga agatggtatt
    10321 caacgtcagg ctctgcattg ccattaccta tccttttatc atccattttt agagcaagac
    10381 ttgcagttag aaagtccctt gccggatgat ttcagtaacc ttattaccca gttatcaact
    10441 aatactctat aaaaactgtc tcagagtata attattatct taaaggagaa aactcatgga
    10501 agtttttgaa agtctcaaag ccaaccttgt tggtaaaaat gctcgtatcg ttctccctga
    10561 aggggaagag cctcgtattc ttcaagcaac aaaacgctta gtaaaagaaa cagaagtgat
    10621 tcctgttttg cttggaaatc ctgaaaaaat taaaatttat cttgaaattg aaggaatcat
    10681 ggatggttat gaggtcatcg accctcaaca ttatcctcaa tttgaagaaa tggtttctgc
    10741 cttggtggag cgtcgcaagg gcaaaatgac tgaagaagat gtacgcaagg ttttggttga
    10801 agatgtcaac tactttggtg tgatgttggt ttacttgggc ttggttgatg gaatggtgtc
    10861 aggagcgatt cactcaacag cttcaacagt tcgtccagct ctacaaatca tcaaaactcg
    10921 tccaaatgta actcgtactt caggagcctt cctcatggtt cgtggtacgg aacgttacct
    10981 atttggagac tgtgccatta acatcaatcc agatgcagaa gccttggctg aaattgccat
    11041 caactcagca atcacagcta agatgtttgg catcgaacct aaaattgcca tgttgagcta
    11101 ttctactaaa ggttcagggt ttggtgaaag cgttgataag gtcgttgaag caactaaaat
    11161 tgctcacgac ttgcgtcctg accttgaaat cgatggtgag ttgcaatttg atgcagcctt
    11221 tgttcctgaa actgcagctc tgaaagctcc tggaagtacg gtagctggtc aagcaaatgt
    11281 cttcatcttc ccaggtatcg aggccggaaa tatcggttac aagatggctg aacgcctggg
    11341 tggctttgcg gctgtaggac ctgttttgca aggtttaaac aagccagtta atgatctttc
    11401 tcgtggatgt aatgcagatg atgtttacaa gttgaccctc atcacagcag ctcaagcagt
    11461 tcatcaatag tgaaaactat aaagcgatat actatgctat actgtagtta tgaaactatg
    11521 tacgaaaagc actgccatta attcctgaga actaaattac tgattggtgt caaaaaggaa
    11581 aacttccaag cgatgatatc ctgtctatac acgacctata gaaatctgta atatgtatgt
    11641 ccgtaaaacg ataatttccc tttttgattt taaatgagta tgaaaagaga attttttcat
    11701 gagaaaacgc ataatattaa gtgtcttgac acctgctatt atgcgttttc tggctctttg
    11761 tcaactgtag tgggttgaag aaaagctaag ctcgagaaag gacaaatttt gtcctttctt
    11821 ttttgatatt cagagcggta aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa
    11881 aggcattg
//
LOCUS       DAVBED010000062        11401 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBED010000062 DAVBED010000000
VERSION     DAVBED010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.062"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQ547_001822"
     CDS             complement(<1..947)
                     /locus_tag="VQ547_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2543629.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQ547_001823"
     CDS             complement(1027..1890)
                     /locus_tag="VQ547_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2543630.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQ547_001824"
     CDS             complement(1893..3794)
                     /locus_tag="VQ547_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2543631.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQ547_001825"
     CDS             complement(4222..4497)
                     /locus_tag="VQ547_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2543632.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQ547_001826"
     CDS             complement(4603..5442)
                     /locus_tag="VQ547_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2543633.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQ547_001827"
     CDS             5584..6432
                     /locus_tag="VQ547_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2543634.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQ547_001828"
     CDS             complement(6525..7442)
                     /locus_tag="VQ547_001828"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2543635.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQ547_001829"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQ547_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ547_001830"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ547_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2543636.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQ547_001831"
     CDS             complement(8705..9049)
                     /locus_tag="VQ547_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2543637.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ547_001832"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ547_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2543638.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQ547_001833"
     CDS             complement(9597..10196)
                     /locus_tag="VQ547_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2543639.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQ547_001834"
     CDS             10666..10965
                     /locus_tag="VQ547_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2543640.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            11184..>11401
                     /locus_tag="VQ547_001835"
     CDS             11184..>11401
                     /locus_tag="VQ547_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543641.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         3615 a         2365 c         1895 g         3526 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aaggaaatca
    11281 tcgccaaact ggactacgac gccccatctt gccctgagtg cggaagtcaa atgaagaaat
    11341 atgactttca aaaaccgtct aagattcctt accttgagac aactggtatg cctactagaa
    11401 t
//
LOCUS       DAVBED010000063        10995 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBED010000063 DAVBED010000000
VERSION     DAVBED010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.063"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            1..269
                     /locus_tag="VQ547_001836"
                     /pseudo
     CDS             1..269
                     /locus_tag="VQ547_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(385..1188)
                     /locus_tag="VQ547_001837"
     CDS             complement(385..1188)
                     /locus_tag="VQ547_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2543642.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1467..2222)
                     /locus_tag="VQ547_001838"
     CDS             complement(1467..2222)
                     /locus_tag="VQ547_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2543643.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2292..4943)
                     /locus_tag="VQ547_001839"
     CDS             complement(2292..4943)
                     /locus_tag="VQ547_001839"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2543644.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4936..5514)
                     /locus_tag="VQ547_001840"
     CDS             complement(4936..5514)
                     /locus_tag="VQ547_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2543645.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5514..5984)
                     /locus_tag="VQ547_001841"
     CDS             complement(5514..5984)
                     /locus_tag="VQ547_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543646.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5971..6549)
                     /locus_tag="VQ547_001842"
     CDS             complement(5971..6549)
                     /locus_tag="VQ547_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2543647.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6832..7227)
                     /locus_tag="VQ547_001843"
     CDS             complement(6832..7227)
                     /locus_tag="VQ547_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2543648.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7323..7577)
                     /locus_tag="VQ547_001844"
     CDS             complement(7323..7577)
                     /locus_tag="VQ547_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2543649.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7586..8920)
                     /locus_tag="VQ547_001845"
     CDS             complement(7586..8920)
                     /locus_tag="VQ547_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2543650.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8920..9153)
                     /locus_tag="VQ547_001846"
     CDS             complement(8920..9153)
                     /locus_tag="VQ547_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2543651.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9422..9562)
                     /locus_tag="VQ547_001847"
     CDS             complement(9422..9562)
                     /locus_tag="VQ547_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543652.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9559..9741)
                     /locus_tag="VQ547_001848"
     CDS             complement(9559..9741)
                     /locus_tag="VQ547_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543653.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9743..10526)
                     /locus_tag="VQ547_001849"
                     /pseudo
     CDS             complement(9743..10526)
                     /locus_tag="VQ547_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3226 a         2419 c         2023 g         3327 t
ORIGIN      
        1 cgacacgatt cttatcatcg gttcctaaga gtaagggaat tcaagcatct atgtcacgca
       61 agggaaacag ccaagacaac ggtatgatgg agtccttctt tgggattctg aaatcggaaa
      121 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gccattatag
      181 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccttg
      241 tgcaatacag aactaaatcc ttcggataaa ttatttgtct aactttttgg ggtcagtaca
      301 cctaaaactt tgatgatata cgttttcttg tgagaatatt tacttcattt ttgcctaaaa
      361 ttcaatgttt actcagtatt tggattatga aaaatcgagg tctaaatcta gatacatttt
      421 ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa
      481 ctcagaacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac gaaaatattt
      541 ggaatgttgc tgaaatggtg tattatcaat atcaaaacca aactcacgaa gatactgaat
      601 caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc
      661 tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg catatgcaac
      721 ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt aatcagagta
      781 cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct gacgaaattg
      841 ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa tagcaagtaa
      901 ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac gtagagaaac
      961 caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg catcctcata
     1021 aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt ccatatacgc
     1081 tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata aatcacgctt
     1141 cgcttcataa gacaagtttg gattgtcaat gttgtaagtt gattgcatag aaatatcctt
     1201 tcaattgttt ttcttcatta ccagtaaatc acgaaattgg ttggaaactg gcttaaacta
     1261 taaaaagtcc tcacaatagg ttctatgata tatatatata tacttcatgt aaataataaa
     1321 agagttataa tcagcactac tgataaattc aataccgatt tcgccatctt aaaacttagt
     1381 caaacgaata ccgttgattt ccagttcatt aagtcgttga cctgtcaaga cttctcgttc
     1441 cttcaactgg aaaagttaag ggggaactaa tacaaatcct ctacgcttct atattcaatg
     1501 atttcatttt tgataatatt ctttttaaac tcaaaatgtt ttaaaggatt atcgattaac
     1561 actaactttg gaatatcatc tagatttgtg accaaggata aaataaaatc cgattgaaac
     1621 tccttgactt tttcaaattc ttttgcagtt aaacgcacac gccccttaga ttttcggata
     1681 ccttttactt cggcaaggta agaatactct tggacatcta cctgaaagtc atatccatca
     1741 ccataaagac gggcatcggt taactgtcca ccttggaatt tttcttcttt atcaaaatga
     1801 aggataaaat aattctcagc ctccattccc gtttcctgta gacgtttgaa tttagttcga
     1861 actattggtt tttcaacgat ggttatgcct gttttcttcc cttcactggc aagtaacatt
     1921 ttaactattt cagcataact atgaacatct tcatttccaa acatcatatc aattaaatct
     1981 ttacgaaaac gataaacttc agctttctgc caccaacctt ttcgattatt gtcaaaataa
     2041 ggatcaaata aatccattct attttttaca actccagttg tttcagcaat tcccagagaa
     2101 accacatagc gataaaactc cgacttgcta gagcattgaa attcttttat aaaaagcttg
     2161 tcaaacttgg caagaccgta gccaattaaa tttaacaatt cataatgagg gtgtttggac
     2221 atcactttct ccatcaatag atattgattt cattatacca aaaaacacgg ctcatcaccg
     2281 tgtttctgtg tttatttcac caacttcttc atctcatcaa tacgtgctac ggtcgcatca
     2341 tacttagctt ggtaatctgc ttgcttgtcg cgttcttttt ggacaacttc tggtttagcg
     2401 ttggcgacga agcgttcgtt gctgagtttt ttgccaacca tgtcgagttc tttctgccat
     2461 ttggcaagtt ctttttccag acgtgccaat tcttcttcga cattcaagag gtctaccagt
     2521 ggcaagaaga tttcggctcc tgtgatgacg cttgacatag ccagttcagg tgcagggatg
     2581 gttgatgcga tttccaagtg ttcaggattt gtgaaacgtt tgatgtagtt gacattgctg
     2641 ttaaagaagg cttccaagtc gctatcgctt gtcttaacaa ggatagtgat aggcttgctt
     2701 ggagcaacgt ttacttccgc acgcgcatta cgaacggcac ggatcaagtc tttaaggctt
     2761 tccacaccag tgtgagcagc aaggtcttca aaggctgggt tgacagttgg gtattctgct
     2821 gtaacgatag atccttctga gatttgtcca aagatttcct ctgtcacaaa tggcatgatt
     2881 gggtgaagga gacgaaggat cttgtccaaa gtgtatagta gaacagaacg tgtgatgact
     2941 ttctcttctt cgttatcgct ataaaggact tccttggtca actcaacata ccagttggca
     3001 aattcttccc agatgaagtt gtaaaggata tgaccagcca caccaaactc gaacttatca
     3061 aagttttcag taacttttgc aatggtttcg ttgagattgt ggagaatcca gcggtccgtc
     3121 acattaccag cctcacctgt tgcaactttt gtgacattgt catgcgccac atccagcgtc
     3181 aaaccttcat tgttcatgag gatatagcga gaaatgttcc aaattttgtt aataaagttc
     3241 catgaagcat ccattttctc gtaagagaaa cgaacgtctt gaccaggagc tgagccgttt
     3301 gacaagaacc aacgaagact atctgtacca tatttatcaa taacatccat tgggtcaatg
     3361 ccatttccaa gagatttaga catcttacgt ccttcttcat cacgaattag accatggata
     3421 agagcatttt taaatgggct ctttcctgta aattcaattc cttggaaaat catgcgtgat
     3481 acccagaaag gaataatatc atagcctgtt acgagtgttg aatttggata gtagcgttta
     3541 aagtcagtag tttcggtatt aggccagccc atggttgaga agggccagag ggcagagctg
     3601 aaccaagtgt caaggacatc ttcgtcctgt ttccagccat cgcccgctgg ggcttcctcg
     3661 ccgacataga tttcgcctgc ttcattatac caagcaggga tttggtgacc ccaccagagc
     3721 tgacgggaaa tcacccagtc gtggacattt tccatccatt gcaggaaggt gtcgttgaag
     3781 cgcggtgggt aaaattccac cttgtcatct gtgtcttggt tggcaatggc gttcttggcc
     3841 aattggtcca tcttgacgaa ccattgagta gacaagcgtg gctcaactac gacacctgtc
     3901 cgttctgagt gaccgactga atggacacgt ttttcgattt tgacaagggc accgatttct
     3961 tccaacttag caacgactgc cttacgagct tcaaaacgat ccatgcctga aaattcaaag
     4021 gcaagctcgt tcatagttcc gtcgtcgttc atgacgttga cttgtggcaa gttatgacgt
     4081 tggccaacca agaagtcatt tggatcgtgg gcaggtgtga ttttcacgac accagtacca
     4141 aacttaggat ctgcgtgctc atcaccaacg attgggatta atttattagc aattggaagg
     4201 atgacatttt taccaatcaa gtccttgtag cgcgggtctt ctgggttgac cgcaaccgca
     4261 acgtccccaa acatggtctc aggacgagtt gtagcaactt caagggcgcg tgaaccatct
     4321 tccagcatgt aattcatgtg atagaaggca ccttcgacgt ccttgtgaat aacctcgata
     4381 tcagaaaggg ctgtgcgagc tgctgggtcc cagttgatga taaactcacc acggtagatc
     4441 cagcctttct tgtaaaggtc cacaaagacc ttacgaacag cttttgacaa accttcgtca
     4501 agagtgaaac gctcacgaga gtagtctaca gagagcccca tcttgcccca ttgttccttg
     4561 atagtagtgg aatattcgtc tttccattcc cagactttcg tcaagaaaga ctcacgacca
     4621 aggtcatagc gggaaatgcc ctcaccacgc aagcgctcct ctaccttagc ctgagtggca
     4681 atccctgcgt ggtccatccc aggaagccaa agggtatcaa aaccttgcat gcgtttttga
     4741 cggatgataa tatcttgcaa agttgtatcc caagcgtgac caaggtgaag tttacctgta
     4801 acgtttggtg gtggaataac gattgaataa ggcttagcct tttgatcgcc tgaaggcttg
     4861 aaaacatcag catcaagcca tttttggtaa cgaccagcct caacctcggc tggattgtat
     4921 ttagatgaaa gttctttaga catgtgtgtg tcctttctct attttgttta ttttattttg
     4981 aatttgctta gcagcttctt ctgcagacaa attcgtatta tttattttaa agtagtggtg
     5041 caactcattc ggttgatatt gggaatttaa ttgaagtgtt tcagcggtct ctaaaatttc
     5101 tctttcagat acctcaatat gtcgttttaa gggtttgtgc tttaatcgat tctccgttcg
     5161 atttcgacgt atgcactctt caagacttgt ttccaactca acaaaaagaa tctcttgatg
     5221 ataatcatcc aacaaattct gaatttgctt taaatacatc agttgatact gatttgaaaa
     5281 atcaattaca tctgttaaaa ttactgatcg ctgatttctt gcacttgctc caaggaatga
     5341 aaaagtgatt ccacgaacaa attcccacat ttcctctgta tagtcctgat agatttctag
     5401 tgcaaaatca atggcttgat ggttataaaa tagggtagca tccgtcagtc gagataattc
     5461 ttgaccaatg gtcatttttc ctgatgctgg agcaccaatg atgaaaagat gcatcaaatc
     5521 acctcccact cactcttcag caaggcatat ctcaaatcat cacagcagtt gccttgagca
     5581 tctttacggt ctcttatgcg agcttcgagg gtaaagccaa gcttttccgc gactcgttga
     5641 ctttgaaggt tatatccaaa gcaagttagt tcaatcttgt gaagacccaa atctttaaag
     5701 gctaagtcaa tcaaggcacg cgcagcttct ggcacataac ctcgccccca atagtctggg
     5761 tgtaaggtat agccgatttc cagcacatca tcttcatggc gatggttgaa atcgacagag
     5821 ccaacgatct tatccgttcc tttgacgaca atcccgtagc ctgctggata ggcgacctct
     5881 ggcaaactag catagtcaaa gatatcctca gcatccgcca cagtacggac tcgtaaaacg
     5941 agacgttctg tttcgatttt atctggcagc tcagttcttg ccatccttct tcctcgcttt
     6001 tttgatgaaa ctgcccttca tatctacacg cttatccaga tagcgataaa cgcgctgata
     6061 tccatctccc atgaaatagg ttggggcaaa cagttgattt ttaaaatgtc ccttttcatc
     6121 caggagttct ggggcaacaa gtcgctcaag aatcttggca aagatgtggc aaataccgtc
     6181 ttcctcaaca atcctatcta cccgacaatc taaaacaagt ggacaggcgt ctaaaatagg
     6241 agtctgagtt cgttcagaaa tttcataatg cactcccaaa cgttccaatt tctcctgatg
     6301 actgataaaa ccagcctgct ccatcgcaag catagaagtt tcatcagaaa tattcacagt
     6361 aaatttttga tactgtttga tctgctctgc ggcattctct ctcgcaacga ctccaatcac
     6421 aacccaatct cctagactat acgaggaact acaggtcgtg atgttatagc caaaattctg
     6481 atcttgatat cctaaaataa aaacaggaaa accataatat agtttattag ttttaaatga
     6541 ttgttttata acaacctcct ttgactaaga cacaaaagaa aagccctgcc atctacatga
     6601 cagggacgaa tgtatttatc cgcggtacca cccaatttcg ggccaagccc gcatctttag
     6661 tctttaaaat aaaaagacag aaatatttca ttttttcagt cattagcaac cagttttgac
     6721 acatttgtgg acttctcagc gccgccactt tctgtaaaat gtgggattca aaacacctct
     6781 aatagctcta ttgtagcaag tttttctcgg aaatgcaagg ctcaagaaaa attacttgaa
     6841 cttgatgcca ttttctttca atttcttgat ggtagctggg ccgattcctt tcaaggcaag
     6901 gagttctttt tcagtccagt ttttgaaatc tgaagcagac ttgattcctt catcatagaa
     6961 agtcttggca cgatcaagtg gaagtccacc caagtttgct gcaaaatctt ctacagaatt
     7021 agctactttt tgagcttgct ctttggtagc ttctactgct tgttcaactt ttttagaaac
     7081 agccttacca gctgcgcttg ctgactgttc tgcacgcttc acgacttttt ttgtctcatc
     7141 tacaacctta gtcacagtac ttgaaaaggc acctgcgcga cggaggccat ttcgtaattg
     7201 ttttttacga ttgagtttct ttgacatgat aaaatccttt caataaaaaa tccctgctct
     7261 gacaaggatt taacataaac attctatcaa gattttagtg aaaaatcaag aatctttctc
     7321 gtttaataat ttcgctcacc aaacaagcct tctggcaaat catggaatcc cttgcctact
     7381 ttgaagtttt caaacttacc aagcaagaac tgataagcat ccaagcgact ctcgtagcga
     7441 atcatggcat ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg actttccttg
     7501 tgcgccatgt cgttaatcat gatttgggta ttgacccaag cttcaaattc cttcataaat
     7561 tcttgttcgt aactcatttt tctccttatt ctaatccacg aaaatagtcc gtatcaatct
     7621 cacggtaggg ctggatatcc tgaacatact ccaacactcc ttggaattct ccgtcttcat
     7681 cgtgtactgc agcataggtg atgtggacaa acttacctcg cgactcagac ttgaaccaca
     7741 tttcatactt gtctttgctt ccctcacgaa gcctcttcat gatagttttg accttgtcca
     7801 agtacttagg cggatggcag agttcgacat tgcgcccgac ttgagacggc gtccgtttga
     7861 aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatct tctttattga
     7921 caaaggtaat ctccataggg agatgattga ggatgagatt ggcctgctcg actgaaagat
     7981 agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt tccttagggg
     8041 taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact tgaccttctg
     8101 ccgtatctag ctgtacaggc tcctctgcaa tcttttcctc aataaagctc tgtcgttctg
     8161 gcacccattt ctctgacgga cggatgatgg catagccata ggcatcgctc tcctccgcaa
     8221 tctgaagcca gtcatcctga gtaaaagact caaggagaat catgaggagg atggactctt
     8281 ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc tttacactgc
     8341 taattgacac ttctggtagt gacttgactg tcgttagagc tgtttgaaag agttccctaa
     8401 tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag cgctccatga
     8461 taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgcccc acaagcccca
     8521 tctgacgcac caagcccttg cgcatctccg caagcatttc ctcgtcttcc atcaactcat
     8581 aggtatctaa caatctacga atgcgaatca aagctgcacg gagggccaaa ttttcttcct
     8641 taaagacacg aactgggtgc ccagggtgtt cggtatctaa aacttcgaca cctttgatag
     8701 catttttaaa aagattggca tggacatcac agagttccat aacatcttca aaagtgacgc
     8761 ccgaatccga gttcatcagc tcgtgctcca taagggaaat ctcgatggct gacacgcccg
     8821 taaaggtcgc atcaaagcga tcttgaaccg actcaggaga ggcgccattg tgcaattcta
     8881 acaaaatatc ccgtaggata tgaatccatt catctgtcat tagtctaatc caatcacttc
     8941 gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg ttagcttaga
     9001 accctgttta agtgatactt tacgaccaac tgtattgcgc attaagggat tggcaagggg
     9061 tttaaaaccc aactccacta gaatttccaa gacttctgga tgcttgtcca ccacttctgc
     9121 aacaggaatt gacacatcga tgatattgtc catgacgacc tccattgtat gttctaatac
     9181 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acagtgtttt
     9241 gaggttgtgg atagaactga cgaagtcagt aaccatacct acagcaaggt gaagctgacg
     9301 tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt ataccatatg
     9361 gagagagatt aaaaaactag cagtggagtt cctgctagtt ttctgcgact tggattacca
     9421 tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga actgcaaaag
     9481 aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa agaatagcaa
     9541 gaattgtcca gaaaaatttc attctctctc ctctggctta atgagccacc gagccgtatc
     9601 cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt catctttctt
     9661 tatcgttttc atcactttta caccttgcac ggtcaaaaag taattaccat aaattttagc
     9721 aaaagctttg ataggattca tattattctc ctttgatgat ttcagcctct tttcggattg
     9781 tttcaacatc ttcttgatat tgaacttcac tatagttgac tagcttggat aattctttct
     9841 gcaagctttc ccccattggt ttcatagttg caaaggttaa accacctgaa atgataccac
     9901 ccaagatagg aataaatttc cccattcctt tggccaaccc tcccttggta agattcacac
     9961 caaatatttt taagactttt ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat
    10021 taggcactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt agcaaacaaa
    10081 gcagcggttc cattcacccc taacattacg cctagataaa gcaagagggt attttgagca
    10141 tcttcactca actcctcacg tgaagcccaa agatcctcat aaccataaat ataacctaat
    10201 tcttgggcca atttcagaga gaaaccataa aattgagcca cataagctgg aatggtaatt
    10261 gccatagcaa gccctccagg taatcctgcc aaaacagaag tcccactcgc taataaaaca
    10321 ttatccctaa tacaggcatt agccactcga tctaagattt cttgagataa gagagacgtt
    10381 ggaccttgtt ccaataaggt aggaatgtcc tgtggaccca attctttgga aaacttatcc
    10441 actaaaaatt tcgaacgatc aaccttaaca actggtagtt ttaccacttg ttgtaatact
    10501 tgcatagcta agtcttgttc agccatatac aaactcctta tttctttttt gcaccttatc
    10561 atattatatt tcctacaaaa aaagcatttt ctaattagat aacattaaaa aatacagaac
    10621 ccctttttta tagtaaaata aaacaagaac aggacaaatc gatcaggaca gtcaaatcga
    10681 tttctaacaa tgttttagaa gtagaggcgt actattctag tttcaatata ttttaaaaga
    10741 atatttttcc atttcaaatt caacctattt tcctccacca aaaaagggct ctataatatt
    10801 tgtagtgggt aaattcccta tggatattat ggagcctatt tttgtgtaga aaaaaagtcc
    10861 catatgacct ataatgaaaa gcgacaaaac aactcattag aaagaatcat atggaacaat
    10921 tacattttat cacaaaactg ctcgatatta aagacccaaa catcaagatt ctagatatca
    10981 tcaataaaga tacac
//
LOCUS       DAVBED010000064        10989 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBED010000064 DAVBED010000000
VERSION     DAVBED010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.064"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQ547_001850"
     CDS             136..2316
                     /locus_tag="VQ547_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2543654.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQ547_001851"
     CDS             2368..3183
                     /locus_tag="VQ547_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2543655.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQ547_001852"
     CDS             3323..4666
                     /locus_tag="VQ547_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2543656.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQ547_001853"
     CDS             5043..6233
                     /locus_tag="VQ547_001853"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2543657.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQ547_001854"
     CDS             6786..7721
                     /locus_tag="VQ547_001854"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2543658.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQ547_001855"
     CDS             7755..8792
                     /locus_tag="VQ547_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2543659.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQ547_001856"
     CDS             8965..9570
                     /locus_tag="VQ547_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2543660.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQ547_001857"
     CDS             9726..10256
                     /locus_tag="VQ547_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2543661.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ547_001858"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ547_001858"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2543662.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBED010000065        10791 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBED010000065 DAVBED010000000
VERSION     DAVBED010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.065"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            135..425
                     /locus_tag="VQ547_001859"
     CDS             135..425
                     /locus_tag="VQ547_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543663.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            449..1165
                     /locus_tag="VQ547_001860"
     CDS             449..1165
                     /locus_tag="VQ547_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2543664.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1294..2109)
                     /locus_tag="VQ547_001861"
     CDS             complement(1294..2109)
                     /locus_tag="VQ547_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2543665.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2106..3011)
                     /locus_tag="VQ547_001862"
     CDS             complement(2106..3011)
                     /locus_tag="VQ547_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2543666.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3409..5538
                     /locus_tag="VQ547_001863"
     CDS             3409..5538
                     /locus_tag="VQ547_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2543667.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5525..5974
                     /locus_tag="VQ547_001864"
     CDS             5525..5974
                     /locus_tag="VQ547_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2543668.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6033..6305
                     /locus_tag="VQ547_001865"
     CDS             6033..6305
                     /locus_tag="VQ547_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2543669.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6659..6850)
                     /locus_tag="VQ547_001866"
     CDS             complement(6659..6850)
                     /locus_tag="VQ547_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543670.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7278..8036
                     /locus_tag="VQ547_001867"
     CDS             7278..8036
                     /locus_tag="VQ547_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543671.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8038..10026
                     /locus_tag="VQ547_001868"
     CDS             8038..10026
                     /locus_tag="VQ547_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543672.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10068..10712)
                     /locus_tag="VQ547_001869"
     CDS             complement(10068..10712)
                     /locus_tag="VQ547_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2543673.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3339 a         2019 c         2255 g         3178 t
ORIGIN      
        1 tataccatat tttgtttcgc aggaagtcta atgctaaaat cttatcagtg agaagatttc
       61 ttaaagttta ttctttgtag tttcatctgt attagtacat aatttaactt agagaaaata
      121 ggaggactaa tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga
      181 aaaggcttac aatgtctaat attagtgaca aagaaactac tgagaagatt ctggcgctag
      241 tcccacaaga cttgattaag cgaatcccgt tttttgtcag aaaacatgct acaacacgta
      301 cgattaaacg tatttcaatt gaataccctg aactctacgc tgtagctcaa acaagtggtg
      361 agattccaga aaaaaacgcg aagaattgcg tcagattatc acaactatct ttgaacaaaa
      421 gatgaataag catagtatta agtagagaat gaaaaaatat tttattggcg gtttgggaag
      481 caatgcctat catagcaagg attttcttca agaactagat tcgcaggtct attttctaaa
      541 tccatatgaa aagcatcttc gagatgaaac agaattgaaa tcatggttta aaaatgagat
      601 tgtagaggaa gaatctatct gtctgatagg tcattctatt ggaggcgatt tagctcgtta
      661 tttcgcatcg gaatttgaag aagtaaagaa actgattctt ttggatggtg gctatctaga
      721 tttagataag attttacctt tggatacaga gttagaggaa actaaaaatt atatcaaatc
      781 tcaaattatt tcggacttag atgttcttac ttctaaagaa aaatctgaag caaagcattg
      841 gtcagaaaat atggagaaag ctgtaagaca gtcctatcac tggaatgttg agtataatag
      901 atatgagttg gctataaatt atgaaaatat agaagcgata ctccgcctac ggagaaaaat
      961 acaagctttt aagagagaag tgggagatac cttgtttatt agtcctcgct atcctaatga
     1021 agctacatgg agagaggaag ccctaaaaga attgccagac tattttgata ctattttttt
     1081 agaaaacttt ggccatgagc tttatactca agcacctaaa gaaatcgcta gtctaatgaa
     1141 tgagtggctc gcttattttc tatgagctac ttgtattgct ggaaatggta taagatgaaa
     1201 atctacaagt cactaatttt catataacaa aaaacgaaca ggctcttttt ctgttattca
     1261 gaagagaact tgttcgtttt tatcttgatt ttcttaaaaa gctctatata catagggatt
     1321 ttctggttta tcgactttgg taaagctgtc gatttccaag gttggaaggt tttgtttgag
     1381 ttctttatgg tagtgattga ccagttttcc tttggctgtt atccaagtgt tgttttcata
     1441 ctgccgggta ttgcccttgg tcagcaatcc atagacacca gaatctgcga tacagtggat
     1501 aatgccgaat cggaacagaa attgactatt ggcatgactg gggtcgttat agacaaagcc
     1561 tgtaaactgg attgtcttgc cctcaaactc atctggatag tcgtagatag cctccatgac
     1621 ttccatatag ttttcattag tgatctgaat actatcttgg gataagtatt tatccgccgc
     1681 cgttcgcatt tccttttcat aggctgattt tgaaaaataa gaactggtat ctggtttcaa
     1741 atattggctt gtcgtccctt cgcttgtctg aatggctaga tctgttcctt ccgatagggg
     1801 gaaatgataa cctttagcag aaacggtctg agaatccaag ctaacagttg ggaaagttaa
     1861 gccgatgaca agtggaatag ccagaagaga aatactcgtc atcttggcca atcggctgtt
     1921 cagatgactg tgggttttga cttgcttcat ccagatatac aattgaacaa ttgccaagat
     1981 aaaggaaagc accatggaga tataggccag ataggaatag tgcatgttga tgtactggtt
     2041 tagtttgccc gacagatgga ggtaaatagt cagttcaaaa tagccagcta aaactaaaaa
     2101 tcgaatcata ggatgactcc aatcaagaga gaatagacta agacgacaag agttacaatc
     2161 gttatgaagt gactgataaa tcgtgctttc aagtaatttt tcatcatgag aatatttttg
     2221 atatccagca ttggaccaat gacgagaaag gccagaactg gtgccaaacc gaaactcgag
     2281 agaagagaag cacctataaa ggcatccgcc tcactacaga gcgaaagaag aaaggccaaa
     2341 atcatcaaga gcaggatggc aaaaagagga gtcgcactga tagaggtcag aatccgagtc
     2401 ggaacgtaga cctgtattat agaagcaaag aggcagccaa ataccaaata acgccccgta
     2461 tcaaaaaatt catcaatggc ctgcacaaag acttgaaaaa ctttttttgc agaactcaag
     2521 taagaaaaat catgctcatg acaagccaga cgattttctt tctgaatcgg ttcttgccag
     2581 aaaaatccta gaaaaattcc tagtattaca gccacaagaa tggaacccag agctcgtaat
     2641 agggcgacat ggaaggagtt gccaaaggca gaataggtcg caaaaagaac aatgggattg
     2701 ataacaggtg ctgtcacaag aaaaggaacg gctgtgtaac tgggaacctt tttttccaga
     2761 aaacgattga tgatggggac gattccacat tcacaagaag ggaaaagcat accgacaaag
     2821 gtcccaaaaa agattctccc ccaacgattt cgagggagaa aatgataaac cttgtcaggt
     2881 gtgatataaa cttcaatcag ccctgagaca atgcttccta ttagaacgaa gggaagggct
     2941 tcaatgataa tggagagaaa aatggctcca gtttgaagta cactagatgg gagttgttga
     3001 aaagcagtca tctagttttt cttttctgct ttggcttttt tctctttgtc atcagggaaa
     3061 gtaacttgtt tcaaatcagg gagtttagca aactcttcaa acatcttgtc caagtcgtct
     3121 cgttttgtaa attttacagc cataggtgta cctcgattct aaagtctacc tctattatac
     3181 tattattttg cggaaaaggg agttttttaa tttgttttcg atagttgata cacttcgaaa
     3241 atctcttcaa accacgtcag cttcgcctta ccgtatatat gtgacttatc cacaacctca
     3301 aaacagtatt ttgagcagcc tgcggctagc ttcctagttt gctttttgat tttcattgag
     3361 tatgaaaagg attggagaaa gccttccagc ttgtggtata atagatttat ggataaaaaa
     3421 tatgaaaaaa tctctcagga tttgggagtg atgttaaagc aaattgatac cgttctaagt
     3481 ttgacagctg aaggggcgac tattcccttt atcgcgcgtt atcgcaagga catgactggt
     3541 agtctggatg aggtggcgat taaggctatt attgatttgg ataaaagtct gacaaatctc
     3601 aatgaccgta aggaagctgt cttagctaag attcaagaac aaggtaagtt gaccaaggaa
     3661 ttggaagaag ctatcttagt tgccgaaaaa ttagcagacg ttgaagaact ctatcttcct
     3721 tataaggaaa agcgtcgtac caaggcaacc attgcccgtg aagctggact ctttcctctt
     3781 gctcgtttga ttttgcagaa tatagttgac ttagagaaag aagctgaaaa gttcgtctgt
     3841 gaaggatttg cgactggcaa ggaagccttg accggtgcag ttgatatttt ggtcgaagcc
     3901 ttatcggaag atgtgacctt gcgttctatg acttatcagg aagtgctgag acactctaaa
     3961 cttacttctc aagccaagga tgaaagtctt gatgaaaagc aggtttttca gatttattat
     4021 gatttttcag agacagttgg aactatgcaa ggctatcgta ccttggctct caatcgtggg
     4081 gagaaacttg gtgtcttgaa gatcggtttt gaacatgcga cggaccgtat tcttgccttc
     4141 tttgctactc gtttcaaggt gaaaaatgct tatattgatg aagttgttca gcaatccgtt
     4201 aagaaaaagg tcttgcctgc tatcgagcgt cgtattcgga cagaattaac tgagaaagct
     4261 gaagaaggag ctatccaact tttttctgac aatctgcgca atctcctctt ggttgctcca
     4321 ctgaaagggc gcgtggttct tggatttgac ccagcctttc gtacaggtgc caagttagct
     4381 gtcgtggatg caacaggaaa aatgctgaca actcaggtta tttatcctgt taaaccagca
     4441 tcagctcgtc aaatcgaaga agccaagaaa gatttagcag atttaattgg tcaatacggt
     4501 gtagagatta ttgccattgg aaatggaacg gccagtcgtg aaagtgaagc ttttgtagcg
     4561 gaagttctga aagatttccc tgaagtcagc tatgttatcg ttaatgaaag tggtgcttct
     4621 gtctattctg ccagcgaact tgctcgtcag gagtttccag acttgaccgt tgaaaaacgc
     4681 tctgccattt ctatcgcccg tcgtttgcaa gatcctcttg cggaattggt caaaatcgat
     4741 cctaagtcaa ttggtgtcgg tcaataccaa cacgatgtca gtcagaagaa actatctgag
     4801 agtctggact ttgttgtcga tacagtggtt aaccaagttg gtgtcaatgt caatacagct
     4861 agcccagctc ttctttcaca cgtagctgga ctcaacaaaa ctatctctga aaatattgtc
     4921 aaataccgcg aggaagaagg aaaaatcact tcacgcgccc aaatcaagaa agttcctcgt
     4981 ctgggagcca aggcctttga gcaggctgct ggtttccttc gtatccctga aagtagcaat
     5041 atccttgata atacaggagt tcacccagag aattacactg cagttaagga actcttcaaa
     5101 cgtttagata ttaaagacct aaacgaagaa gcccaaagca aactcaagtc cctttcagtc
     5161 aaggaaatgg ctcaagagct agacctcggt ccagaaaccc ttaaagatat cattgcagat
     5221 cttctcaaac caggtcgaga tttccgtgat tcctttgacg cacctgtgct tcgccaagat
     5281 gtcctagata tcaaagacct agtggtaggt cagaagctag aaggtgttgt gcgtaacgtt
     5341 gttgacttcg gtgccttcgt tgatatcggg attcacgagg acggcttgat tcatatttct
     5401 catatgagtc gcaagtttat caaacaccct agtcaagtgg tgtcagttgg agatttggtg
     5461 accgtttggg tcaagaaaat tgatactgaa cgtgaaaaag ttaatctgtc gctcctcgct
     5521 ccaaatgaaa ctgactgatt atgtcaagca ggtttcacta gaagacttcg ggagagcttt
     5581 tatccatcat gtccagtgga ataggcgtct acgttcgaca ggtgggcgat ttttccccaa
     5641 agatgggcat ctggatttta atcccaaggt ttatcagaaa ctgggtatgg aggtttttag
     5701 gaaaattgtc cgacatgaac tctgtcatta tcacctttat ttccaaggga agggctatca
     5761 acacaaggat cgggatttta aggaactgtt gaaagcagtg gatggattaa ggtttgtacc
     5821 atccttgccc aatagtaact ctaaaccact caagctttat cgttgtcaat cctgccagca
     5881 aaggtatcag cgcaagcgta ggattgatac caaacgctat cgctgtggac tttgtcgagg
     5941 taaattgctt ctgataaatc agcctgagga ctgatgaaag ccgagcctcc ccgtgatata
     6001 ctatgtctaa cctagcagaa agaggaaata tcatgaacag taaattttat aaaatgagac
     6061 gcaatcgcat gatttcagga gttctggcag gtctgtcaga caagtggaat tttgatgtta
     6121 ccctagttcg tttcttgttt gccattttta cagttgcaaa ctttggactt ggcgtgatta
     6181 tctatatcat cctagcttct atcatgccta ccaaggaaga aatcgaagca gaaatgtacg
     6241 gaacaggccc acgtaaacgc aaagaagccc aagccattga cgacaatgaa ggctggtttt
     6301 ggtgaggttc tacagaagat ttggaataag caaaaagctt taaatcaata gtctaaactg
     6361 cttgatttaa agctttttta cttttatact caataaaaat caaagtgcaa actaggaagc
     6421 cagccacagg ctgtaattta gtcggcaatg tgaagttgac atagtttgca ctttgatttt
     6481 tgaatagtat taataatatt tcgccagctt catccacaaa ctatagtgga ttggaactag
     6541 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactatc ctgatcgatt
     6601 tgtcctgttc ttatttcatt ttattataaa agcagtaatt taaactcagt tttttaatct
     6661 atttttgctg ctgagacaat acatttttgg aaaaatggtg gatgctgata acaactgata
     6721 accagcaaat aacataagca gtgccggtaa attctgtacc gataaagtgt gtgtgttcaa
     6781 ctaagagctg accgatgaat ggagagagca gatagagaag tccgatgagt atatgttctt
     6841 tgtgtttcat taaagcgcac cttctttcct tataggttga acgacttgca agtgttaaat
     6901 tgaatggtat gttatctagg taagcttact caaatgatag ttcccgcttc ctcctttcca
     6961 aagtaagcct tttcatactt atattttaca actttaaaaa taggaaatca aatcattttc
     7021 taagtaattt tgcttatatt tcacccaatc ttacaaaaat gtaagattaa agtctctttt
     7081 gtaaggttag gttatggcaa gcggtctttt tttgatgtaa actagactca taaagaacaa
     7141 aggagtaaca tcatgaaaca aatcttacat aagaaaacta gaaaaccaag tcacaaagaa
     7201 attgagcgcg ttcagctggg atgcactatg atgcaagcta catttcattt gatgggatat
     7261 taagaaagga gattctcatg acacttttag atgtaaaaca cgttcaaaaa atttataaaa
     7321 cacgttttca gggcaaccaa gtagaagccc tcaaggatat tcactttacc gtcgaaaagg
     7381 gtgactacgt tgccatcatg ggtgagtctg gttctggtaa atcaactctt ctcaatattc
     7441 tagctatgct ggataaacca agtcgtggtc aggtttactt gaatggaact gacaccgcaa
     7501 ccattaaaaa ttcacaggcc tctagcttcc gtcgtgaaaa gttgggcttt gtcttccaag
     7561 actttaactt gctagatact ctatctgtaa aggacaatat cttgcttccg cttgtcttgt
     7621 caagaagacc tattacagag atgatgaaga aattggtggt gacagctgag aatctgggaa
     7681 taaaccaatt acaagagaag tacccttacg agatttctgg tggccagaaa cagcgtgtag
     7741 cagtagcacg cgccatcatc actgaacctg aaattctcct tgcggacgaa ccgacaggag
     7801 ctcttgactc caagtcatct gcagccttac ttgatgtctt tgatgaaatc aatgagcgcg
     7861 gccaaaccat tctcatggta acccactcaa cagcagcagc tagcagagct aaacgtgtac
     7921 tctttatcaa agacggcatt ctttacaatc aaatctaccg tggagagaag acagaacgtc
     7981 agatgttcca agaaatctct gataccttga ctgtcatggc aagcgaggtg aattagtatg
     8041 tttcgattaa ccaataagtt agcggtatcg aacttgatta aaaaccgcaa actctactat
     8101 ccttttgcgc tggctgttct cttggcagtc actgtcacct atctctttta ctctctaacc
     8161 ttcaatccca agattgctga aattcgtgga ggaacaacca ttcaggctac acttggattt
     8221 ggtatgtttg tcgtcaccct tgcgtcagcc attatcgttc tctatgccaa tagttttgtc
     8281 atgaagaacc gttccaagga actaggaatt tatggcatgt tgggcttgga gaagcgtcat
     8341 cttatcagta tgacctttaa ggagttagtg gtatttggga ttctaactgt tggagcgggt
     8401 atcggtattg gagccttgtt tgacaagtta attttcgctt tcctgctcaa actaatgaaa
     8461 ttgaaggttg agctggttgc taccttccag acgaaagttg tcattacagt gcttgttgtc
     8521 ttcggtttga ttttcctagg cctcatgttc ctgaatgccc ttcgaatcgc ccgtatgaat
     8581 gccctccagc tctctcgtga gaaagctagt ggagagaaaa aaggtcgctt ccttcctctc
     8641 caaaccattc ttggttccat aagtttagga attggctatt atcttgccct tacggtaaaa
     8701 gatcctctta cagccttaac aaccttcttc atagctgttt tactggttat ctttgggact
     8761 tatctcttgt ttaatgcagg gattaccgtt ttcctccaaa tcttaaagaa aaataagaaa
     8821 tactattacc aaccaaataa tctcatatct gtttctaact tgattttccg tatgaagaaa
     8881 aatgcagttg gactagccac catcgctatc ttgtcaacaa tggttttggt aaccatgtca
     8941 gcagcgacaa gcattttcaa ttcctcagaa agctttaaaa aagttctaaa tcctcatgat
     9001 tttggggttt cagggcaaaa tgttgaaaaa gaagacttgg acaaactctt gagccagttt
     9061 gcaagtgaca aaggttatag tgtcaaagag aaagaagtac ttcgttacag taactttggt
     9121 attgcaaatc aagaaggaac taagttaact atttttgaaa aaggacaaaa ccgtgtccaa
     9181 ccaaaaacag ttttcatggt atttgaccaa aaagattatg aaaatatgac tggtcaaaaa
     9241 ctgtctctat caggaaatga ggtcggactc tttgcaaaga atgagggagt taaagaacag
     9301 aaagctctaa ctctaaatga tcatcaattt tctgtaaaag aagaatttac taaagatttt
     9361 attgtcaacc atgttccaaa tcagtttaat attttgactg ctgattacaa ttaccttgtt
     9421 gtacctgatt tacaagcctt tttggatcaa ttcccagatt cggctatcta taatcagttt
     9481 tacggtggta tgaatgtaaa tgccagtgaa gcagaacaac tcaaggtcgc tgaggagtat
     9541 gaaaaatact tacaaaagtt taatgctcaa ttaaacactg aaggtaacta tgtgtatggt
     9601 agcactctag cagatgctag tgctcagatg agtgccctct ttggtggtgt cttctttatc
     9661 ggtattttct tatccattat ctttatggtc ggaaccgttc tggtcatcta ctacaaacaa
     9721 atttctgaag gatatgaaga ccgtgagcgc tttattatct tgcagaaagt cggtttagat
     9781 caaaagcaaa tcaagcaaac catcaacaaa caggttttaa ctgtattctt ccttcctttg
     9841 ctctttgcct tcctacatct agcctttgcc taccatatgc ttagtctgat tttaaaagtg
     9901 attggtgtac tggatacgac tatgatgttg attgtgacct tgtctatctg cgctatcttc
     9961 ctcatcgcct atgtgctgat tttcatgatt acttcaagaa gttatcgcaa gattgtgcaa
    10021 atgtaaaaaa gatacctcga cttcaaaatc gaggtatttc ttgtattcta aatgctgaaa
    10081 agttgttcga gcaggaaggt aactcccatg gtcaagagac caatagcaag gttccgaatc
    10141 atagctgttt tggttggggc ttttccaagt ctagcacttg tgtaaccagt gagaagaagg
    10201 gccacaccga caataaggac ggtagcaggg atgcggtaat cacttggaaa aatggtcact
    10261 gacagcattg gaggcaaact tctaaggaaa aaggcaacga agctagaaat ggcagcgtgc
    10321 caaggattgg taaattcttc atactcaatc ccatattttt cctctaccag agccttgagt
    10381 ggatttttaa gaaagatctt attagtcaag agttgggcag aagttttgaa ttcttcattt
    10441 tggatataag cagcatagag ggattttttg gctagttccc tatcttggtc tagcaagagt
    10501 ttttctcgcg aaacggcagc ttcctcggta tcttttggag ttgaaacgga tacatattct
    10561 ccaccagcca ttgaaaaggc accagctaag atagccgcaa atcctgataa aaagataatc
    10621 cagatattgg tcgtggcact ggcaaccccg ataaccacac cagcaatgga aataattcca
    10681 tcgttagcat caagaacacc cgcacgcagg atatttaaac gacctgcaaa atttgaatca
    10741 atttcgtgat ttgtttctga cgctaaattt caagttcaag ttagccatcc a
//
LOCUS       DAVBED010000066        10048 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBED010000066 DAVBED010000000
VERSION     DAVBED010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.066"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ547_001870"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ547_001870"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2543674.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VQ547_001871"
     CDS             complement(2039..2971)
                     /locus_tag="VQ547_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2543675.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VQ547_001872"
     CDS             complement(2968..3825)
                     /locus_tag="VQ547_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2543676.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VQ547_001873"
     CDS             complement(3829..5175)
                     /locus_tag="VQ547_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2543677.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VQ547_001874"
     CDS             complement(5188..5472)
                     /locus_tag="VQ547_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2543678.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VQ547_001875"
     CDS             complement(5476..7506)
                     /locus_tag="VQ547_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2543679.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VQ547_001876"
     CDS             7698..8705
                     /locus_tag="VQ547_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2543680.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VQ547_001877"
     CDS             8708..8908
                     /locus_tag="VQ547_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2543681.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ547_001878"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ547_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2543682.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ547_001879"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ547_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2543683.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10048)
                     /locus_tag="VQ547_001880"
     CDS             complement(9899..>10048)
                     /locus_tag="VQ547_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2543684.1"
                     /translation="YYLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNAN
                     GEWVG"
BASE COUNT         3258 a         2132 c         1627 g         3031 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattcattt aagtaata
//
LOCUS       DAVBED010000067         9628 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBED010000067 DAVBED010000000
VERSION     DAVBED010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.067"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            364..951
                     /locus_tag="VQ547_001881"
     CDS             364..951
                     /locus_tag="VQ547_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543685.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1038..1241)
                     /locus_tag="VQ547_001882"
     CDS             complement(1038..1241)
                     /locus_tag="VQ547_001882"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543686.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(1538..2242)
                     /locus_tag="VQ547_001883"
     CDS             complement(1538..2242)
                     /locus_tag="VQ547_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2543687.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2312..4138)
                     /gene="glpO"
                     /locus_tag="VQ547_001884"
     CDS             complement(2312..4138)
                     /gene="glpO"
                     /locus_tag="VQ547_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2543688.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(4180..5688)
                     /gene="glpK"
                     /locus_tag="VQ547_001885"
     CDS             complement(4180..5688)
                     /gene="glpK"
                     /locus_tag="VQ547_001885"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2543689.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5847..7274)
                     /locus_tag="VQ547_001886"
     CDS             complement(5847..7274)
                     /locus_tag="VQ547_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2543690.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7439..8311
                     /gene="hslO"
                     /locus_tag="VQ547_001887"
     CDS             7439..8311
                     /gene="hslO"
                     /locus_tag="VQ547_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2543691.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EGLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8298..9278
                     /gene="dusB"
                     /locus_tag="VQ547_001888"
     CDS             8298..9278
                     /gene="dusB"
                     /locus_tag="VQ547_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2543692.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9508..>9628)
                     /locus_tag="VQ547_001889"
     CDS             complement(9508..>9628)
                     /locus_tag="VQ547_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543693.1"
                     /translation="ASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT         2743 a         2186 c         1923 g         2776 t
ORIGIN      
        1 aaatacgtct atttattttt tattgttttt tattgtagag cagacccaag cgaatgaaca
       61 taggttgtaa aaagcaaatg aaaaaactgc gaggataata gcttctgtgt ctaaataacc
      121 catttcgaga cctcttttca acaacaacaa gcctgtagtt tcgataacga tcaaacataa
      181 aaatatataa aaaattttcg cattaagcat attgttaccg ctttcttttt atttggtttt
      241 attgtataat aaaagttgaa aaaaatcaaa aatacaaagg agtttccgtt atgtctaaga
      301 tgtttaaatg catgtgtttg ctagttatgt ctgttttctg tatgtctagc atttccccgt
      361 cgcttgtttg tttttgctga tgatagctta tcggcaaact ctaaagttgt atctggtgag
      421 gctcagtttg agaatggctc atcagtgcgg ttcggagata cgcaagtaaa tattttaagc
      481 gatgaagttc ttgaggttgt caatccagat ggaagtgtag acactattga acgacgtgct
      541 gacggcgtct atatcaatgg ggcattttat atggcttatc aaaagaatga aatcgaccta
      601 aatatatctt ttagatcata cgatcctaat gtttggaatt acgtcaacac aatacatggg
      661 aataaacaag ctaacacatt cgctaacttc atgactggtg ctggaatcag ttatatgatt
      721 ggtaggatag gtactttatt ggggggtcca tggggtgcaa taattggtgg agcatatttt
      781 ggtatacaag cttatcagtc ttacttggat tcacaaagcc catatccata ctacataaca
      841 agtacttata tccatgttgc tcaaaaaaaa tggaagttta tcactgaata ctatagaaac
      901 tcaaactata ctgggtatgt aaaaaccgta acaacctacg tgaatttcta aaatataaac
      961 cctgcctaga tataaaggca gggtttatat tttagttaat tgctcaagta atttgtaagc
     1021 ataatacttg cgaaactcta tttgttcaag cggttcaaaa gctcttgttt tttatcctca
     1081 agctcagctc tcctttgctc gatttcttca cgtttttggg cgatttctgc ttgcgcctcg
     1141 ggagtttcca aagtgccttg tgacttgtga aattctacta gcatatcaac gatttttggg
     1201 tctaattcgt tgacataatc aggatttgac catttcggca cgttgcttgc aggtgcttgc
     1261 tttttgccgc cttttttggg cgttttggct tgttgttcag ctttctgact gtagttgacc
     1321 tcgtggaatt ttcgtgcttg atatgatgcg ttttattatg agaagattta cttcattttt
     1381 tgctgaaatt gggctcttgc ccaagctcta tcaacataat tgttttctaa tactcaatga
     1441 aaatcaaaga gcaaactagg aagctagccg taagctgtac ttgagtacgg taaggcgacg
     1501 ctgacgtggt ttgaatttga ttttcgaaga gtataaacta gaaaagtgag aatacaagca
     1561 ctgccaaggc tgctccgata acagggccta caacaggaat ccaagcgtaa gaccagtctc
     1621 cgtctccctt gtttggaatt ggcaagatgc tgtgcatgat acgaggtcca aggtcacgag
     1681 ctgggttcaa ggcataacct gttgtcccac ctagtgatag accgataccg acaatcaaag
     1741 ttcccactgc aaaggttccg atacctgcct gaaaatcgta aagacccaaa gcaaagattg
     1801 tcaacaccaa aacaaaggtt ccaaggattt cgctaatcaa gtttgataca gtatccttga
     1861 tggctggtcc agtactgaag gttgccagga tattgcctgc attttcttct gcctcatagt
     1921 gaggtttgaa ttgcaaccaa accaaaatct gacccagcat ggcccctgcg aactgggcta
     1981 agatataagg caaaacggaa gcccaaggca aaccaccttt taaggccaca ccgatggtca
     2041 cagctgggtt taaatgagct ggactgagct tgccagatac aaagactgca accgcaactg
     2101 caatccccca acccatagta atcacaatcc aacctgagct attgctcttg gttttaggaa
     2161 gaaccacacc tgcaacaaca ccatttccta gaagaatcag gattaaagtc cctagaaatt
     2221 ctccaaataa ttcattcatc atctttctgt ctccattaaa aagaagggac gggcgacaag
     2281 gaatgctgcc ctccacctct tttatttttt cttaattttt taattctgct aaatcgttgt
     2341 tagcgagagc tgcttcgaca tcagcacggt aagttgcttt ttcttcttct gtccagtcat
     2401 agaatcgtcc catttcatcc aaaattggct caacgatgct atccaagcta tcacgcataa
     2461 agagcatatg gttggtacga cgaagaagga agtcaactgg gctaagagcc aactcgttgc
     2521 gcattgcata gtgaagggac aaagtatctg ccaagctgag tcctggcgct tgttccaagc
     2581 tgtgagcaag tgcaaagact ttcggtgcat ttgaaccgta aagatttgcc agatagtgag
     2641 cttccttgct atccaaacca cgtgatactc caagttgcgc aaaggcttcg atttctgaat
     2701 ccacatttgc tgggttcaat tctccacctg aaacagggta agttttagaa ttgatcaatt
     2761 taaagctacg gtcaaattct gctttgagga tgtcaaccac gcgctccata gctccttcag
     2821 ccatcttacg gtagtctgtg attttaccgc cagcaagagt caaaagacca ttgtcatcac
     2881 ggtccaagct agacccacga gaaactgcag atggatccaa atgtttctca gatgtgctac
     2941 tttcaagctt gctgacagca gactcaacat cttcacgtgt tttttctttg gagagataag
     3001 attcaacagt cgcaatcaag ttgtcaaagc tttcatcact gatggtaccg ttatttccac
     3061 cattatagtc agaggcactg ttccctgcaa tcaatggacg aagacctgcc cagctgcttt
     3121 cgatatcatc aatggtgatg ttggattctg gaaagcggtt gttgacaatg ccaagtagat
     3181 aatctacatc ttcttgagtt acttttggat gctccaaatc acctgtgtag tctgtatcag
     3241 ttgtaccaaa gtaagtcttg ttttcacgtg ggagaacaaa gaccatacga ccgtcaccca
     3301 aacctgtgtc aaagtaaact ggctgtgaaa ccttgatttt gcttgaatcc actaccaagt
     3361 gaactccctt agttgggcgc atttgtgaga attgcgttcc cttattagac aaattacgta
     3421 ctttatcact ccaaggacct gttgtattaa taaccagacg ggccttgatt tcaaatactt
     3481 ggtctgtcaa gagatcacga gctacaacac ctgtaatctt gccactttcg tcaaagagga
     3541 agccttctgc cttcacgtgg ttggcaatga gggcaccgtc ttggttggca cgtttgatgt
     3601 tttcaatcac gagacgcgca tcgttgttac ggaagtcaag atacactcca cctcctacca
     3661 agccttcctt cttcaagttt ggctggcgtt ccaagacttg atccttgctc aaaaccttgt
     3721 tcgcagttgg tgtgttgcta acacctgcca agaggtcgta caagtccatg gctactttaa
     3781 gacggaagag gctaaaggtt gctccatctt catcgtaaac tggtaagagc attgggtctg
     3841 gttttggaat gtgtggagcg atttgttgaa ccactgcacg ttcagaaacc gtatctgaga
     3901 ccacttctac gtcgaattgt ttaaggtaac gaagtcctcc gtgaaccaat tttgttgaac
     3961 gactagatgt tccttctgca aagtcttgca tttcaatcaa accagtctca agaccgctag
     4021 ctgccgcctg caaggctaca ccagctcctg tgattcctcc accgataatc aagaggtcca
     4081 gggtgcgttc ctgcattttt ttaattgaca attcacgtgt tttctttgaa aattccatat
     4141 ttacacactt tctaaataaa tcgctttatt ctgccagtat tagtcgtcta cttccgcaaa
     4201 gacttgagtt gctttcacag ccttcttcca gcccttgtag agttgttcct tgcgagattc
     4261 gttcatagat ggctcaaaga gttctcctgt ctcgttcaag agtttcaact cgtccaagtc
     4321 tttccagtac cctactgaca aacctgctag gaaggccgct cctagagctg ttgtttccag
     4381 gtttttagca cgtgcaatgt caatgcctaa aatatccgcc tggaactgca tgaggaagtt
     4441 gttcatggct gcaccaccat ccaccttcag tacttgaatg gcggtctgag tatccacttg
     4501 catggtgtcg atgatatcac gcacttgata agcaatagat tgcaaagtcg ccttgataaa
     4561 gtcttctttg cttgttccac gagtcaaacc aaagacggaa ccacgagcat tttggttcca
     4621 gtatggagcg cctagacctg taaaggctgg aacgacataa acttcatcgt tgttgtgaga
     4681 atcacgagcg tatttttcag attctggtga attttcaacc atgcgaagac cgtcacgaag
     4741 ccactgaata gcacttcctg cgatgaagat agaaccttcc aaggcataat aaaccttacc
     4801 gttgattccg taaccaatgg ttgtcaagag gttgttttca gacaactgca tctcttcccc
     4861 agtattcatg atgatgaaag agcctgttcc ataagtattc ttaaccatac ctggctcaaa
     4921 agccaactgt ccaaagaggg ctgcttgttg gtccccagcc atacctgaga ttggcacctc
     4981 tccaccgtag aaatggaatg gagctgtctt gccgtagatt tcggagttag aacgaacttc
     5041 tggaagtata gccttcggaa tgttaaggat ttccaaaatc tcatcatccc atttgagttc
     5101 tttaatgtta taaagcatgg tacgagctgc atttgagtag tcagtcacgt gagccgcacc
     5161 gtcagtcaat ttccaaacca accaagtatc gatagtacca aagagcaatt cccctttttc
     5221 tgctcgctct tgagcacctt ctacatgatc caaaatccaa cgaaccttgg tagcagagaa
     5281 gtaagcatca ataatcaaac cagtcttttc atggaatttt tccacataac cttggctttt
     5341 tagttgctca gccaaaggtg ctgtctggcg tgactgccaa acgatagcat tgtagatagg
     5401 aagtcctgtt ttcttatccc agacaaccgt tgtttcacgt tggttggtaa tcccgattgc
     5461 ctcgatttga tttggcttga caccactttc gatgaaagca cccgcaataa ctgactgaac
     5521 agagttccaa atttcattgg cattgtgctc aacccaacct gcctgaggga aaatctgggt
     5581 aaactctttt tgactcgagc taaccttttc cccttttttg ttgaaaatga tggcacgaga
     5641 acttgtagtt ccctggtcaa tggccatgat gtatttttct tgtgacatgt actgtcctcc
     5701 tgataaagat cttgaggtgt ttcctcttta cacttactag tatacaaaat aaagcgcttt
     5761 cttgtttatc aacttttttt aatttttaaa aaaatgtgag gagattgtgt gaatttcaca
     5821 aaaaagacct agattaacca agccttttaa gtgaataata actgacgaat ccctgccaaa
     5881 tcttccatat ccaagtcgtt ttttaaataa tagactggtg tctgttcctt cttatgaatc
     5941 gggttattgg taaccagcaa atcataatgc cgactagggt cataagcttc aatggtaata
     6001 aaacgattgt attccaaata ccgtttcaaa atggctgcca tccttgaaaa gacaagaaaa
     6061 ccagatgtca aatccagacc aatccgcata tgctggccac cgttttcagc catatattcg
     6121 attaactgga gccattccca gagaatcttc ttatctaaat ctgtcccctg ttgaaaagca
     6181 ggtagagcat gaaaaatctc ctctgctgtc tctttaaaat catgttccat cagtaaatat
     6241 ggatgacgat tctctaactg gtacttgtag cgatcctgta aaatatagcc cttatagaga
     6301 tagacttgag cacaaagctg actgagttca taggtgacat ggtcctctgt ataatccccc
     6361 aatagttcct ccttcttcat ttcttgaatc aattgcgtca gtaaatctgc caactgccct
     6421 ccaaaaccaa gaatatactc catagtatga agaggaagaa tgcgatgaga taggagaaaa
     6481 gagaagaata tcatcatctc accatcctca actcctagtg gaatatgttg cccagcaaaa
     6541 aaggacggaa cctttctcag caaacgaaga taaaagatat tgtcaaaata ccctcgcatt
     6601 ttctcttcta tgacttgaaa ctgacaagca ttgacccgaa gacgttgttg actgatgtga
     6661 gcccagagaa ccaagtccaa tttctgcccc gcagacaaac ttgcaccgca gatttcctct
     6721 aaattggcaa tctcctgttt tctctctggt ttctgcatgt gaccttccca ttcctgactc
     6781 gaccagacct ttcggaaaag acagaaatag aaatagcgaa tctgatgctc tggacctctc
     6841 cagcgtccat tttggatgga taaatcaaat tctgacaaaa tctgatttaa accagccaag
     6901 tgacgaccaa gcgtagcctc gctaatcacc aattcttgag ccagctgatg ggctaaaaac
     6961 tgttggtggt agagaagata aaccaaaatc tggtatttaa cagcactatc caaaaacaag
     7021 ctccgaatat ctctcccctt ggtagctgca ccgatagaca gacgcagatt ttcatcttct
     7081 gagtgaatag tcagttctaa gccactatcc aaagccttgt cattgagcag ggtgacatat
     7141 ttggttaggg ttgcttttga aaatcctgtt tcttccatta cagccttgac ggtcgtctga
     7201 gactcttgta atagaaagga aaggattgaa aattgaccac actcggcttt ctccatcaaa
     7261 tctcctaaat acatttgtta cccctttcat tttctacctt aagcatagca taaatcttac
     7321 aaatgctgaa ataatctgtt tctcttttta ttttcatgct gatttcctgg tccattatcc
     7381 tgaaaatcag taaacacacg gctccccctt tgggcatttt tatgctaaaa tagtagctat
     7441 ggataaaatt attaaaacta tatcagaaag cggagccttt cgtgcttttg tccttgatag
     7501 cacggaaacc gtccgcactg ctcaagaaag acatcaaacc caagctagct caactgtagc
     7561 gcttggtcga actcttatcg ctagccagat tctcgcagcc aatgaaaaag gaaataccaa
     7621 acttacagtt aaggtgttgg gctctagctc tctaggtgct attatcaccg tcgctgatac
     7681 caaggggaac gtcaaaggct atgttcaaaa tcctggtgtt gacatcaaaa agactgcgac
     7741 tggtgaaggc ctagtcggac cttttgttgg aaatggtcaa ttcctcgtta tcacagacta
     7801 cggtgctgga aatccttaca actctataac tcccctcatc tctggagaaa tcggtgaaga
     7861 ccttgccttt taccttactg aaagccaaca aacgccttca gcggtcggcc tcaatgtcct
     7921 tttggacgag gaagacaagg tcaaggttgc aggtggtttc ctagttcaag tcttgccagg
     7981 agccaagaaa gaagagattg ctcgctttga aaaacgcatc caagaaatgc cagctatctc
     8041 tactcttctc gaaagcgacg accatatcga agccctcctc aaggctatct acggggacga
     8101 agcctacaag cgtctttctg aagaagaaat ccgtttccaa tgtgactgta gccatgaacg
     8161 ctttatgaac gctcttgcca gccttccaag ctcagactta caggaaatga aagaggaaga
     8221 ccacggggca gaaatcactt gtcaattctg ccaaactact tacaactttg atgaaaagga
     8281 cctggaggaa ctcattcgtg acaaatctta atacaccttt tatgattggc aatattgaga
     8341 ttcccaatcg taccgtttta gcgcctatgg ctggcgtgac caactcagcc tttcgtacca
     8401 tcgcaaaaga gctcggagct ggactcgttg taatggaaat ggtctctgac aagggaatcc
     8461 aatacaacaa cgaaaaaacc ctgcacatgc ttcatatcga tgagggcgaa aaccctgtct
     8521 ctatccaact ttttggtagc gatgaagaca gcctagcacg cgcagcagaa ttcatccaag
     8581 aaaacaccaa gaccgatatc gtcgatatca acatgggctg ccctgtcaac aaaatcgtga
     8641 agaacgaagc tggagctatg tggctcaagg atcctgacaa gatctactct atcatcaaca
     8701 aggtccagtc tgtccttgat atcccactta ctgtcaaaat gcgtaccgga tgggcggacc
     8761 catctcttgc agtagaaaat gccctcgctg ctgaggctgc aggtgtttct gccctcgcca
     8821 tgcatggccg tacccgtgaa caaatgtata ctggccacgc agaccttgag accctttaca
     8881 aggttgccca agctctaacc aagattccat tcatcgccaa cggtgatatc cgtactgtcc
     8941 aagaagccaa gcaacgcatc gaagaagttg gtgctgacgc agtcatgatt ggccgagctg
     9001 ccatgggaaa tccttacctc ttcaaccaaa tcaaccatta ctttgaaaca ggagaaatcc
     9061 tacctgattt gacctttgaa gacaagatga agatcgccta cgaacacttg aaacgattga
     9121 ttaacctcaa aggagaaaac gtcgcagttc gtgaattccg cggcctcgct cctcactatc
     9181 tccgtggaac atctggcgct gccaaactcc gtggagccat ttcgcaagct agcaccctgg
     9241 cagagattga agccctcttg caattggaga aggcttaata gtttaaaacc cgtaactctc
     9301 ttaaagagcc tcttgaatgc cgccattctt tcctcatcaa aaaaactccg tagtctctag
     9361 cgctataaat ccggctagag attacagagt tattttttta tctaaacttc ctacaagggt
     9421 atattatcta ctgaaaggat atggtatttg tagggaatac tttaaagagt tcttacagga
     9481 agtcagtatt aactagttat attaggttta gtttacccat tcaccattgg cattgactct
     9541 atagctatct acagttgtgt tgactgcaag ggcacctgag ccattgacat agtaccattt
     9601 atctgatact ttgaaccatt ggcttgct
//
LOCUS       DAVBED010000068         9472 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBED010000068 DAVBED010000000
VERSION     DAVBED010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.068"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQ547_001890"
     CDS             150..686
                     /locus_tag="VQ547_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2543694.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQ547_001891"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQ547_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQ547_001892"
     CDS             complement(892..1107)
                     /locus_tag="VQ547_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2543695.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQ547_001893"
     CDS             1205..1525
                     /locus_tag="VQ547_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543696.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQ547_001894"
     CDS             complement(1556..1894)
                     /locus_tag="VQ547_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543697.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ547_001895"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ547_001895"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2543698.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ547_001896"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ547_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2543699.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQ547_001897"
     CDS             complement(3164..3952)
                     /locus_tag="VQ547_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2543700.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQ547_001898"
     CDS             complement(4529..4768)
                     /locus_tag="VQ547_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2543701.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ547_001899"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ547_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2543702.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQ547_001900"
     CDS             5230..5439
                     /locus_tag="VQ547_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543703.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQ547_001901"
     CDS             5918..6139
                     /locus_tag="VQ547_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543704.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQ547_001902"
     CDS             6222..7025
                     /locus_tag="VQ547_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2543705.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQ547_001903"
     CDS             complement(7081..8622)
                     /locus_tag="VQ547_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2543706.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQ547_001904"
     CDS             complement(8624..9106)
                     /locus_tag="VQ547_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2543707.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQ547_001905"
     CDS             complement(9106..>9472)
                     /locus_tag="VQ547_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2543708.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBED010000069         8844 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBED010000069 DAVBED010000000
VERSION     DAVBED010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.069"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQ547_001906"
     CDS             complement(135..1103)
                     /locus_tag="VQ547_001906"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2543709.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQ547_001907"
     CDS             complement(1248..2063)
                     /locus_tag="VQ547_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2543710.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQ547_001908"
     CDS             complement(2088..2585)
                     /locus_tag="VQ547_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2543711.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ547_001909"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ547_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2543712.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQ547_001910"
     CDS             complement(4033..4548)
                     /locus_tag="VQ547_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2543713.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQ547_001911"
     CDS             complement(4550..4993)
                     /locus_tag="VQ547_001911"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2543714.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQ547_001912"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ547_001912"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQ547_001913"
     CDS             complement(5180..5647)
                     /locus_tag="VQ547_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2543715.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQ547_001914"
     CDS             complement(5848..7134)
                     /locus_tag="VQ547_001914"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2543716.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQ547_001915"
     CDS             complement(7365..7601)
                     /locus_tag="VQ547_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2543717.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQ547_001916"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQ547_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>8844)
                     /locus_tag="VQ547_001917"
     CDS             complement(8699..>8844)
                     /locus_tag="VQ547_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543718.1"
                     /translation="KLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALFSCS
                     CFN"
BASE COUNT         2836 a         2104 c         1425 g         2479 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttat
//
LOCUS       DAVBED010000070         8498 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBED010000070 DAVBED010000000
VERSION     DAVBED010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.070"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ547_001918"
     CDS             226..6657
                     /locus_tag="VQ547_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2543719.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQ547_001919"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQ547_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQ547_001920"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQ547_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQ547_001921"
     CDS             7602..7829
                     /locus_tag="VQ547_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543720.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7905..8457
                     /locus_tag="VQ547_001922"
                     /pseudo
     CDS             7905..8457
                     /locus_tag="VQ547_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3204 a         1211 c         1682 g         2401 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaagctta tcgtcaactg gaagaagctg aacttgttgg atgttgggcg catgtgagaa
     7981 ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga gctaaaggtt
     8041 tagcttattg tgatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
     8101 aacgactaca gaaacgtcaa gaacatctcc agcccctaat ggaagacttc tttgcttggt
     8161 gccgccgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca
     8221 agtatgaaga aacctttaag actattttga aagacggaca tctggtcctt tccaataatc
     8281 tagctgaacg cgccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc
     8341 ttttagcctg agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga
     8401 gctaaagcaa gagctattat tatgagcttg ttggaaacag ctaaacgtca tcaattatag
     8461 tgcgttgaat ctataacagt acgcatcgac tgctaaaa
//
LOCUS       DAVBED010000071         8353 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBED010000071 DAVBED010000000
VERSION     DAVBED010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.071"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..1039
                     /locus_tag="VQ547_001923"
     CDS             <1..1039
                     /locus_tag="VQ547_001923"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2543721.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1055..1531
                     /locus_tag="VQ547_001924"
     CDS             1055..1531
                     /locus_tag="VQ547_001924"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2543722.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1565..2146
                     /locus_tag="VQ547_001925"
     CDS             1565..2146
                     /locus_tag="VQ547_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543723.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2211..3218
                     /locus_tag="VQ547_001926"
     CDS             2211..3218
                     /locus_tag="VQ547_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2543724.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3208..3528
                     /locus_tag="VQ547_001927"
     CDS             3208..3528
                     /locus_tag="VQ547_001927"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2543725.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3591..5366
                     /locus_tag="VQ547_001928"
     CDS             3591..5366
                     /locus_tag="VQ547_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2543726.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5367..6752
                     /locus_tag="VQ547_001929"
     CDS             5367..6752
                     /locus_tag="VQ547_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2543727.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6775..7386
                     /locus_tag="VQ547_001930"
     CDS             6775..7386
                     /locus_tag="VQ547_001930"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2543728.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7497..8353)
                     /locus_tag="VQ547_001931"
                     /pseudo
     CDS             complement(7497..8353)
                     /locus_tag="VQ547_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         2724 a         1197 c         1702 g         2730 t
ORIGIN      
        1 tataaaagtt atggatgagc gttttggaca ttctatttat atttatgaat cggaaacatt
       61 gtcggataat caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt
      121 tgaattattg acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt
      181 attagcacca ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt
      241 actattgttt ttaggaacaa tgttagcatt aaaaattttt catctacctt cagaaactaa
      301 gagattttta aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta
      361 tggctcattt tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat
      421 gattatatta gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc
      481 ttcaggacta caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgt
      541 gtggtgtgtt attctgcttg gcttgttatt tattgctgtc ggaatgttga tgcctgatat
      601 gagactgtta tttgtattag ggaaatgggt atctattttt aatgctgtgg gaattttggt
      661 tgtttctatt attcaagcca aaagcttgtc aggtattgga gcaggattgt ttaatctata
      721 taacatttca tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt
      781 atctggagca agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaacatt
      841 ggctaaacta acaattggat tagtattatt cattctttta catgcgatca atatttttct
      901 atcgttacta tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa
      961 gttttatgag ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa
     1021 ggttattaca aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc
     1081 aacctatgga ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagtgg
     1141 tatggggtct gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga
     1201 acagccagaa aagtttgcct ctgctttgat attgcaatta ctgcccggaa cacaaggatt
     1261 atatggtttt gttattggaa ttttgatttg gttgcaatta actccagaac ttcctttaga
     1321 aaaaggcgtt gcttatttct ttgtagctct tccaattgct attgtaggat acttttcggc
     1381 taagcatcaa ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga
     1441 attcatgaag ggagcaattt tggctgccat ggtagaaacc tatgcaattc ttgcctttgt
     1501 cgtatcattc attttgaccc ttcgtgtata agaaattaat ttgctattca aaggaggtgt
     1561 ctaaatgagc aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg
     1621 gcgtatgaaa ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc
     1681 ggtcattgta aagaaaaaag aagtggaaca tgaacgaaag ttaaaagaat tacaacagaa
     1741 atatcaaata atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa
     1801 acagaaaata ttaaaagaac tttttcaatc tgctttaata gaaatggaat cttggagtgc
     1861 agataaagaa atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat
     1921 agtaactttt ggggagcgga ctttagctaa attcaatctg gaacaattag agaaattgaa
     1981 attctctttt ccaaatcatt tatttagtga acagcctatc tcaaatgaat caggcttact
     2041 tatttcaata ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc
     2101 taaggaagaa agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt
     2161 aatccttctt agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta
     2221 atcttttttc aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag
     2281 ataaatttca aaaaattata caatccaaag atacggagac aatggcattt atcttagaag
     2341 caactcccta tcatttatcg attgacgttt tagaaaatcc tagtcagaca gagacttcgc
     2401 taatgacaaa attagtcaat gattatagat gggcctatgc tgaaagtccg tctaataaaa
     2461 ttgtgacttt atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta
     2521 aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag
     2581 aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat tttatggttc
     2641 atgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg
     2701 tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg
     2761 tgctgtctca ggttattgtc gcaatgattg acttttataa tattattact gtaaaacgtg
     2821 gtttatctca aaataagagt catggggata ttttacaatt actttcagat gaaggaagta
     2881 tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata
     2941 aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa
     3001 caatttcatc ttctgagtta gaatttttat gtgatttatt attgtataaa attttagatc
     3061 aaggaaggta caatgtagat gggccgttag tacttgctag atatttattg ggatgtgagt
     3121 ttgaagtaaa gaatctcaga atgattatat cagctcttca aaatacaatt ccctttggat
     3181 caataaaaga aaggatacgc ccgcattatg gaagctaata agtataaaat tggcataatt
     3241 ggtagccgtg atattatttt accctttagc atgattgggt ttgatatatt tcctgcctat
     3301 caagaacaag aagctataaa tactctaaga aaattagccc aatctgatta tggtgtcatt
     3361 tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattctcaa
     3421 gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa
     3481 cgtatagagg ataatgtgga gaaagcagta ggacacaata ttttataata atgtacaaaa
     3541 ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact ttgactcaag
     3601 ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata
     3661 ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa
     3721 gagatcaggc atctatccaa gtctatgagg aaacatctgg tcttggtccg ggagaacctg
     3781 ttgttacaac tggagaacct ctctcggttg aattaggacc aggattgatt tctcaaatgt
     3841 ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag
     3901 ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt gattccacta
     3961 tagcaattgg tcaaaaagtg agtacgggtg atattctagg aactgtcaag gaaaccgagg
     4021 tagttaatca taaaattatg gttccttatg gagtatctgg cgaagtcgtt tctatcgcat
     4081 ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct
     4141 ataaaggaac gcttatgcaa aaatggcctg ttcgcaaggc gcgtcctgtt tctaaacgtt
     4201 taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc tttccagtaa
     4261 ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca gttgtacaac
     4321 accaagtagc taaattttcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg
     4381 gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac
     4441 aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc
     4501 gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact
     4561 ctgtcgccat tatggctgat tcgacttcac gttgggcaga agcactacgt gaaatgtcag
     4621 gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg
     4681 ctgaatatta tgaaagagcg ggacgttctc aggttctagg gattccagaa cgtgaaggaa
     4741 ctattactgc tattggagct gtatcgccac ccggtggaga tatttcagaa ccagttactc
     4801 aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagagac
     4861 gtcattttcc tgcaattaac tggcttacat cttattcact ctataaagac agtgtgggaa
     4921 tttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact
     4981 acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt
     5041 ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac
     5101 agaatgcttt tgattcagta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa
     5161 gtaatatcct aacttttgct gatcaggcaa atcatgcttt agagttaggt tcttacttta
     5221 cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgcgaagt aaatatgttt
     5281 cagaagatag attagatgaa atcaaaatta tttcaaatga gattacacat caaattcatt
     5341 tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg
     5401 aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag
     5461 ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag attcacgaag
     5521 ataaagcaat ggttcaactt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa
     5581 ttcgttttgc tggtcatgca ctagaattgg ctgtatctga ggatatggtt ggtcgtattt
     5641 ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag
     5701 atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga
     5761 cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat
     5821 tttcaggttc gggcttacct cataatgaat tagcagctca gatagcaaga caagcgactg
     5881 ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag
     5941 aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcagtcttat
     6001 ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa
     6061 ccgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata
     6121 tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc gcgccgtgaa gttccaggta
     6181 gacgaggcta tccgggatat ttatatacaa atttatcaac tctatatgaa agggctggtc
     6241 gcttagttgg taaaaaaggt tcagtgacac agattcctat tttaacaatg ccagaagatg
     6301 acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt
     6361 ctcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttatct tctctctctc
     6421 gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga
     6481 atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca gtagtattag
     6541 gagaatcggc tttatctgat gtagataaat tgtatgtgag atttacaaag cgttttgaag
     6601 aagagtacat caaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg
     6661 ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc
     6721 ttgataaata tttacctttg gtagaagttt aatccagaaa tggagtgatt atctatggta
     6781 cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgaaaaca
     6841 gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt
     6901 tctttgattc gtgagaataa tcgacttcgg aaagaagtag aaagttatct aattgataat
     6961 ctaaaatctt ttgcagttgc taaatcatta aagaactctc taatggtgga ggaattattt
     7021 tcaattccat cgaaagaaat tgaattattt attgagaaag aaaatatcat gagtgtaaca
     7081 gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta
     7141 tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat tgataaatta
     7201 ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca
     7261 cgtagacgtg taaatggttt agaatattcg attattccaa acttgtcgga aactattcat
     7321 tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg
     7381 aagtagttcc tttatttaga tttttaatta gatgaacaaa tatcagcttg gataaggcgg
     7441 taagcctttc taagcttttt taggctcttt gtcaactgta gtgggttgaa aaaaagctaa
     7501 gctcgagaaa ggacaaattt cgtcctttct tttttgatat tcagggcgat aaaaatccgt
     7561 tttttgaagt tttcaaagtt ccgaaaacca aaggcattgc gcttgataag tttgatgaga
     7621 ttattggtcg cttccaattt ggcgttagaa tagtgtagtt gaagggcgtt gacgattttc
     7681 tctttgtcct ttagaaaggt tttaaagaca gtctgaaaaa gaggatgaac ctgctttaga
     7741 ttgtcctcaa tgagtccgaa aaatttctcc ggttccttat tctgaaagtg aaacagcaag
     7801 agttgataga gctgatagtg atgtttcaag tcttgtgaat agctcaaaag cttgtttaaa
     7861 atctctttat tggttaaatg catacgaaaa gtagggcgat aaaaatgttt atcgctgagt
     7921 ttacgactat cctgttgtat gagcttccag tagcgcttga tagccttgta ttcatgagac
     7981 tttcgatcca attgattcat gatttgaaca cgcacacgac tcatagcacg gctaagatgt
     8041 tgtacaatgt gaaagcgatc caacacgatt ttagcacatg ggaaaagttg tctagctaag
     8101 tcatagtaag gactaaacat atccatagta ataattttga cgcgacatcg gacggctcta
     8161 tcatatttaa gaaagtgatc tcggatgaca gcttgtgttc taccctcaag aacagtgatg
     8221 atattgagat tgttaaaatc ttgcgcaatg aagctcatct ccatctcccg attgaaacag
     8281 tcactccccg gactgtttca acgtcccaag acataatctc aggcagattt ctaaaattac
     8341 actcaaagtg gaa
//
LOCUS       DAVBED010000072         8109 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBED010000072 DAVBED010000000
VERSION     DAVBED010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.072"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQ547_001932"
     CDS             120..497
                     /locus_tag="VQ547_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2543729.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQ547_001933"
     CDS             732..2123
                     /locus_tag="VQ547_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2543730.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQ547_001934"
     CDS             2237..3079
                     /locus_tag="VQ547_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2543731.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQ547_001935"
     CDS             3352..4113
                     /locus_tag="VQ547_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2543732.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ547_001936"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ547_001936"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2543733.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQ547_001937"
     CDS             5660..7696
                     /locus_tag="VQ547_001937"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2543734.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQ547_001938"
     CDS             7738..7995
                     /locus_tag="VQ547_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2543735.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2555 a         1431 c         1794 g         2329 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaactat
//
LOCUS       DAVBED010000073         7893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBED010000073 DAVBED010000000
VERSION     DAVBED010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.073"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQ547_001939"
     CDS             101..1078
                     /locus_tag="VQ547_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2543736.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQ547_001940"
     CDS             1075..2157
                     /locus_tag="VQ547_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2543737.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQ547_001941"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQ547_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ547_001942"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ547_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2543738.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQ547_001943"
     CDS             complement(5761..6630)
                     /locus_tag="VQ547_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2543739.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQ547_001944"
     CDS             complement(6853..7533)
                     /locus_tag="VQ547_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2543740.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQ547_001945"
     CDS             complement(7491..>7893)
                     /locus_tag="VQ547_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2543741.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBED010000074         7220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBED010000074 DAVBED010000000
VERSION     DAVBED010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.074"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQ547_001946"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQ547_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQ547_001947"
     CDS             complement(684..1127)
                     /locus_tag="VQ547_001947"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2543742.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQ547_001948"
     CDS             complement(1157..3379)
                     /locus_tag="VQ547_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2543743.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQ547_001949"
     CDS             3790..4032
                     /locus_tag="VQ547_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543744.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQ547_001950"
     CDS             4372..5001
                     /locus_tag="VQ547_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2543745.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ547_001951"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ547_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2543746.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBED010000075         6905 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBED010000075 DAVBED010000000
VERSION     DAVBED010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.075"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..332
                     /locus_tag="VQ547_001952"
     CDS             <1..332
                     /locus_tag="VQ547_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543747.1"
                     /translation="GLTNGELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDN
                     VRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEAL
                     LSCSCFN"
     gene            393..1355
                     /locus_tag="VQ547_001953"
     CDS             393..1355
                     /locus_tag="VQ547_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2543748.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1532..2539
                     /gene="gap"
                     /locus_tag="VQ547_001954"
     CDS             1532..2539
                     /gene="gap"
                     /locus_tag="VQ547_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2543749.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2606..3442)
                     /locus_tag="VQ547_001955"
     CDS             complement(2606..3442)
                     /locus_tag="VQ547_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2543750.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3568..5763
                     /locus_tag="VQ547_001956"
     CDS             3568..5763
                     /locus_tag="VQ547_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2543751.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5816..5968
                     /gene="rpmG"
                     /locus_tag="VQ547_001957"
     CDS             5816..5968
                     /gene="rpmG"
                     /locus_tag="VQ547_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2543752.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5978..6154
                     /gene="secE"
                     /locus_tag="VQ547_001958"
     CDS             5978..6154
                     /gene="secE"
                     /locus_tag="VQ547_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2543753.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6210..6746
                     /gene="nusG"
                     /locus_tag="VQ547_001959"
     CDS             6210..6746
                     /gene="nusG"
                     /locus_tag="VQ547_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2543754.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2149 a         1201 c         1499 g         2056 t
ORIGIN      
        1 caggtctaac aaatggtgaa ttaatcgctc caatgactta cgaagagacg atgacgagcg
       61 acttttttga agtatggttt cagaagtttt tcttaccaac attaaccaca ccatcggtta
      121 ttattatgga taatgtaaga ttccatagaa tggggaagct agaactcttg tgtgaagagt
      181 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
      241 catgggttca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttacg
      301 aggctctttt gtcttgttct tgtttcaatt gactatatat cacggataca gttgggaaag
      361 aagctattaa acatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg
      421 ggcaagaaat ggatctgagt caaacgatgc cttcttatgc tcaagtagtg agtctttatg
      481 atgatacaag tatctctgtt agtagtaatg agacggacaa agtgttggct ggctccctct
      541 atactgatac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
      601 aacagacagg aaaaaatttg acagctaatg atcttattgg caaatcagtc tcagccagca
      661 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
      721 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
      781 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
      841 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
      901 tgctttctca acagagagtt cttgatattg tgattatctt tattcgtgtt attcagggat
      961 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
     1021 tttacatcaa tatcatgcag cgttccaagg aaataggtgt catgaaggca gttggttatc
     1081 agaatcgtga tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
     1141 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
     1201 acttttaccc atccatcact aaagtttttg aattaaatct tttatctgtt ttaggaactc
     1261 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     1321 aaatggatcc tgtagaaccg ttacgctatg aatagtaagg gattccttga tttacagtct
     1381 taaaaagaaa ctaacataga aaaacaatgg acatacttgc aattcaactc aaatagttgt
     1441 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     1501 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     1561 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     1621 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     1681 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa
     1741 attcatcaaa gtttctgctg aacgtgatcc agaacaaatc gactgggcta ctgacggtgt
     1801 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     1861 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     1921 tgtattcaat actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     1981 atgtactaca aactgcttgg ctccaatggc taaagctctt caagacaact ttggtgttgt
     2041 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     2101 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     2161 aactggtgct gcaaaagcta tcggtcttgt aatcccagaa ttgaatggta aacttgatgg
     2221 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     2281 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     2341 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     2401 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     2461 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     2521 cgcaaaaatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     2581 ttatatggaa aaatggatga cacgatcatc cattcttttt taattctttt tcaaatgtat
     2641 ttgaaagggt agtgaaagtt agcttctcta aagtaagtgg gtgggtaaag gaaagtcgga
     2701 aggcatgaag cataagccga cttgtctttg atttactatt atagagaggg tcgcccagga
     2761 taggaagatt atgatgcgaa aggtgcacac gaatctgatg ggttcgccct gtctttagct
     2821 tgcaacgagc caaggaagtc ttgtttgaga attgctttaa tctgcttaca tacgtttcag
     2881 catattgccc attttttgca tcaactattc tttttctacg atcatggcga tcacgtccaa
     2941 ttttgtctct gaaaacaagt tcttttctgt tgatatttcc atcaactaga gcccaatatt
     3001 ctctagaaat ctcttttttc tccaataagc gattgagaat gggcaggata aaaggatttt
     3061 tggcaaagag aactaagcca ctggtttcca tgtccagacg atgaacgaca tagcaggttt
     3121 ggccaacata ggtactgaca tggttaagaa gggcaatttc gtttggttga ttaccatgcg
     3181 ttttcatccc ctctggtttg tttacaataa tcaagtattg atcttgataa acttcctgca
     3241 ctaagtctgg gttgccccaa gggatcgtct tttggggata atcttcctcg tcaaaagtca
     3301 actggcaaac atctccagga tttacgattt cgttccagtg gacttcttct tgatttatca
     3361 aaatatgttt cttgattctc aaaaaatgac ggatttttct agggatgagg agttgttcct
     3421 caagtaattg ctttaccgtc atttgaggta gagaggcggg taatgtaaat gtgaattgca
     3481 tacagatatt gtaacaaaaa aagccctatt tggataggaa atagctaaat tcttgtcttc
     3541 ctatgatgaa gatgataaaa taaacgcatg aaattagata aattatttga gaaatttctt
     3601 tctcttttta aaaaagaaac aagtgaacta gaggactctg attctactat cttacgtcgc
     3661 tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga ttcgaaaatt ctggcgtcgt
     3721 tatcatctaa caaagattat ccttatacta ggtttgagtg caggcttgct agttggaatc
     3781 tatttgtttg ctgtagccaa gtcgaccaat gtcaatgatt tgcaaaatgc cttgaaaact
     3841 cggactctta tttttgaccg tgaagaaaaa gaggctggtg ccttgtctgg tcaaaaggga
     3901 acctatgttg agctgactga tatcagtaaa aacttgcaga atgctgttat tgcgacagaa
     3961 gaccgttctt tctataaaaa tgacgggatt aactatggcc gtttcttctt ggctattgtc
     4021 actgctggac gttcaggtgg tggctctacc attacccaac agctggctaa aaacgcctat
     4081 ttatcacagg atcaaactgt tgagagaaaa gcgaaagaat ttttccttgc cttagaatta
     4141 agcaaaaaat atagtaagga gcaaattcta accatgtacc ttaacaacgc ttattttgga
     4201 aatggtgtgt ggggtgtaga agatgcgagt aagaaatact ttggagtttc tgcatcagaa
     4261 gtgagtctgg atcaagctgc gactctggca gggatgctca aggggccgga actgtataat
     4321 cccttgaatt ccgtagaaga ttctactaat cggcgcgata ctgtcttgca gaatatggtt
     4381 gcagcaggat atattgataa aaaccaagaa accgaagctg ctgaagttga tatggcttcg
     4441 caattgcacg ataagtatga aggaaaaatc tcagattacc gttacccctc ttattttgat
     4501 gcggtggtta atgaagctgt ttccaagtat aatctaacag aggaagagat tgtcaataat
     4561 ggctaccgca tttacacaga gctggaccaa aactaccaag caaatatgca gattgtttat
     4621 gaaaacacat cgctatttcc gagggcagag gatggaacgt ttgctcaatc aggaagtgta
     4681 gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg gtcaagttgc tgacaatgat
     4741 aaaactggat tccggaattt caactatgca acccaatcaa agcgtagtcc tggttctaca
     4801 attaagcctt tagttgttta tacgccagca gttgaagcag gctgggcttt gaataagcag
     4861 ttggataacc ataccatgca gtatgacagc tataaggttg ataactatgc agggatcaaa
     4921 acgagtcgag aagttcctat gtatcaagcc ttggcagaat cgcttaatct acctgctgtt
     4981 gccgctgtta atgatttggg tgtcgacaag gcttttgagg caggcgaaaa attcggactc
     5041 aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg gaagcggtgt tgaaaccaac
     5101 cctcttcaaa tggctcaagc atacgctgcc tttgcaaatg aaggtttaat gcctgaagct
     5161 cattttatta gtagaattga aaatgctagt ggacaagtta ttgcgagtca taaaaattca
     5221 caaaaacggg tgattgataa gtctgtagct gacaagatga ccagtatgat gttggggact
     5281 ttcaccaacg gtaccggtat tagttcatcg cctgcagact atattatggc agggaaaact
     5341 ggaacaactg aagcagtttt caatccggag tacacaagtg accagtgggt aattgcttat
     5401 actccggatg tagtgattag ccactggctt ggctttccta ccactgatga aaatcactat
     5461 ctagctggct ctacttcaaa cggtgcagct catgtcttta gaaacattgc caataccatt
     5521 ttaccttata cgccaggaag tacctttacg gttgaaaatg cttataagca aaatggaatt
     5581 gcaccagcca atacaaaaag acaagtacaa accaatgata atagccagac agatgataat
     5641 ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg aggctagccg ggctatctca
     5701 gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt cgatagtcaa tctatttcgc
     5761 taagatgctt gtcaaagcct agctttcttg ttataatgga taggatggag gcgttatggc
     5821 actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg agaaactatt caatcaagat
     5881 cagcggaaac cccaagccta cacgactaga agtaaataaa ttttgtaagc attgtggcaa
     5941 gtacactaca cacagagaaa cgagatagga gagagcgatg cgttttattg gagatatttt
     6001 tagacttctt aaagacacaa cgtggccaac tcgcaaggaa agctggagag attttcgttc
     6061 tatcatggaa tacacagctt tctttgtagt aattatttac atttttgacc agttgattgt
     6121 ttcaggtttg attcgattta ttaacatttt ttagaagatt agtggagtta attacactag
     6181 aaatcttcta tattatgaaa ggaaatatca tggatagttt tgataaaggg tggtttgttt
     6241 tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa
     6301 cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg
     6361 aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag
     6421 aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat
     6481 ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg
     6541 acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc
     6601 aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg
     6661 ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa
     6721 acctaaacca aatcgcagaa ttataaccct gagagaggct ggagcctctc ttttttgtgc
     6781 agtttaggag ctaaagggaa cagaatggag aaaatgtaac aaatgtgttt tctaatctgt
     6841 tagactgtat ctagaaaggg gaaaattatg attaaagaat tgtatgaaga agtccaaggg
     6901 actgt
//
LOCUS       DAVBED010000076         6834 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBED010000076 DAVBED010000000
VERSION     DAVBED010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.076"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQ547_001960"
     CDS             complement(201..1625)
                     /locus_tag="VQ547_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2543755.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ547_001961"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ547_001961"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2543756.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ547_001962"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ547_001962"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2543757.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6834)
                     /locus_tag="VQ547_001963"
     CDS             complement(6611..>6834)
                     /locus_tag="VQ547_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2543758.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2022 a         1502 c         1239 g         2071 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVBED010000077         6641 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBED010000077 DAVBED010000000
VERSION     DAVBED010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.077"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            19..576
                     /locus_tag="VQ547_001964"
     CDS             19..576
                     /locus_tag="VQ547_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543759.1"
                     /translation="MYDKPLLLPLIPFSIIIALVQKLYRIENQQLFLLKSKVLTILES
                     KKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIKPYLSESVREQIDLLEVKRFKKIN
                     HPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKILEVRPDFVLIEQNIDDSLNSSQPL
                     SLSLAISEIQLLLEVYMGIKHVSTK"
     gene            956..1330
                     /locus_tag="VQ547_001965"
     CDS             956..1330
                     /locus_tag="VQ547_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2543760.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            1538..2440
                     /locus_tag="VQ547_001966"
     CDS             1538..2440
                     /locus_tag="VQ547_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543761.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            2496..2735
                     /locus_tag="VQ547_001967"
     CDS             2496..2735
                     /locus_tag="VQ547_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2543762.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            2732..3460
                     /locus_tag="VQ547_001968"
     CDS             2732..3460
                     /locus_tag="VQ547_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543763.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            4595..4834
                     /locus_tag="VQ547_001969"
     CDS             4595..4834
                     /locus_tag="VQ547_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543764.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            5384..>6641
                     /locus_tag="VQ547_001970"
     CDS             5384..>6641
                     /locus_tag="VQ547_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2543765.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         2343 a          909 c         1233 g         2156 t
ORIGIN      
        1 tattttttct ttacttttgt gtatgacaaa ccgttgcttt tgcctcttat tccattttct
       61 attatcatag cattagtaca aaaactttat agaattgaga atcaacaatt atttctgtta
      121 aaatcaaagg tactaacaat actggaatct aagaagaatt gtgagtttaa tcttcaggat
      181 tatcatgaaa tttggaaatt gcaatcaaaa tctgagttgc catgcgtggc tttatcttat
      241 atcagtttga tcaagccata tctttcagag agcgtgcgtg aacaaattga tttattagaa
      301 gttaagcgat ttaaaaaaat aaatcatcca atatcacttt atggtatgtt ggatgttata
      361 aaattaaatc tatatttacg gcattataat gaaaaaaata aatatgaatc aatgttaaag
      421 aaaattttag aggtaagacc agactttgtt ttaatcgagc agaatattga tgatagttta
      481 aatagctcgc aaccattatc tttatcttta gccatttcag aaatccaact tttgcttgaa
      541 gtgtatatgg ggatcaaaca tgtttcaacc aagtgataaa accagaataa tatttgccat
      601 tataggggca agttgcatat tagtcagtat gtatcttatt ccacttatta aaactgagaa
      661 taaattttgg gaaatacttt tatttatatt aggtgtattg ctaattggaa ttgcgttact
      721 aagtcaaaaa aaataaattt tgaaatagta ttagtgagtt cgcaatcatt tattgctagt
      781 ggtttagaac tgttaagttt caaacaataa ttgattttaa accttaggta acctataaaa
      841 acaaataagg tagagaaagg atatcttatc taggtagcta agtgataaaa acacagtcgt
      901 ctatcacttg ttaggaaact atcctaacta tgcttaataa aaaaggagaa aataaatgga
      961 actcgtatta ccaaataatt atgttgttct tgagcaagaa gagatgatgt atcttgatgg
     1021 gggattttct attccgagat ggcctgttgc aacagccatt aatatagctt ttaatggtgt
     1081 tttaggtgga ggagcaatca gtctagttag aaattatatt cgtaattatg gtttgcggcg
     1141 agttacaagc gcaattgctg gagcagctgc aagatatgtt ggggtacgag ttgcaaatag
     1201 agtggcagga tttgcactgt ctgctattaa tggatttgca gcttggatgt caattggcga
     1261 tgctattaca acaatctggg ccaacaatga tgtaaatagg agagacccaa atttaaacgc
     1321 cttgtggtaa ctagatatgg gtattaaaat ggaaaaaatt tttgttatta ttttttttgt
     1381 atgtctattt atatcatcca taactttttt agcctatgat tttgttagcg aagaaataaa
     1441 aaagttgatt atttggatta atgtcgtttt tttgatttta atcatagcaa tgatgattta
     1501 tccaaaatta agaaaatgat aaggacactg taaaattatg atacgtaaac taattgtttt
     1561 cttactaatg ctccctcttt ttgtcttgtg gctagagttg catgtcctag tgaataactt
     1621 actattgaat ctagaatctc cccttgattt tgtgattagt atgagtcttg ctttctgtag
     1681 tttgatttta tcaaaaatag ttttagacat actatacgca ttgaaagatt tatacaagaa
     1741 agaaggtctt attaagattt ttccctttat ttttataaga aggaaaaaag tgaatgtgag
     1801 attctcgccc tatttttcat tccatcgtaa aagtttgtcg cctgatgatt taagatctag
     1861 gattatatgg agttttattc ttgaaattgc tattatccta gtatttattt taaaaattcc
     1921 ttttgcaatc atcatgctta ctacaatatt tttctggact ataatggata tcaatcatct
     1981 cgtttttaat aagacggaat ttctttttaa tcaaaacaaa tggcaaaaag aagattcatt
     2041 tgaaagtaat ttgcataaga tattgatgga caaaatacaa aaatcagaat taagctattc
     2101 tgacttaatg tcccttcttc tctatgatgc gatgaaccaa tccacctttt taacggatag
     2161 tgaacttttt gaggatattt tgaaaaaaat cgaagattct cataacaccc ttctgtgtac
     2221 aggtcttgtc gagttactgc tgtatgagat ttctattagt aacaataaca actggcaaga
     2281 aaaggttgat aaaattagaa tacagctcat cagaatcaat caattagatt ttttctatta
     2341 tacaagttgg ttaaggcaaa attttgattt ctgtatgaat agagagtatc ataaaatgaa
     2401 atctcggaaa ttattactga gtaataaaaa gatagtttaa gttcgtccta tttgtaaaac
     2461 aaatgaaaca atttcaacta aggaggagaa aacaaatgga acttgtatta ccaaataatt
     2521 atgttgtgat tgatgaagaa gtaatgatgt atcttgatgg gggagcttat ttaagcaagc
     2581 gtgcttgtca aggaatttgc gcagcagcag gtgtattggc tacagcagca gggaaaatag
     2641 cttactgtat tggatatggt gttcttaata gaggttgtga tattaacgag aacccttatc
     2701 cttgggatgg attcatatct gcaacagtaa gatgagtaat gtagataaga ttcgaaaaat
     2761 acacatcatc gtgtgttggg tgtatatatt tttatcattc agggcgatta taaatgatac
     2821 ggagtatttt ttgcttattt ttttagcttt tatctactca atagtatcac tacctctata
     2881 ttctgtgaaa aataaaatag tatctatctg tctagttata aattcgattc tgttaatgag
     2941 tttccccatt ttaatcaata agtttttccc agaaagtttt ttgacttata ccgtattaat
     3001 aagtgttttt atcctagagt tagcaatctt tcatttaatt aggaaagatt ttgatattaa
     3061 attgactaac gaatataaga aaattagtca gtttagaagc aaggtgtctc aatctccttg
     3121 gataaaatat ttagagattt ctagttttat attaactata tttccatcta ttctttatgg
     3181 taaagttgat aatcatgtac tgactcttat ctttttgata aaaatttgtg tagatactac
     3241 gataaaattt ttattcatca gattatttga cacaagtact ttaatgaaga ggagaatatt
     3301 ttttcttttc gcattggatg ttatagctta cttattttta ggatatcttt tagtgattca
     3361 aaaagcaggc tatttgtttt cggttttact tcttttttct aatttttcag ttccatttat
     3421 caaagaaaag gaatacgaat tatttaaaaa tagcaagtaa tagaaatatg gattaaatct
     3481 tagaacggct taaaatcaga tatgataaag ggaaatagtc ttatctaggt aactaagtgc
     3541 tacaaacaca atcgaggatc acttgttagg attacatttt aatcatgctt aataagaatg
     3601 gagaattcct atggggattg tattactctg aagtttcgaa taccttagtt ctcgtgattt
     3661 tgagctattc tagctttaga atccttcaga acgtaaaatt ttaagcagtc aaagacttag
     3721 aatagcctga aaacatttat tttatagcaa ttctaggctt agaattgctc atatatatgt
     3781 atttgagctg ctcgatagtt aggacagctc tattctgaga aatctgagct atcaatgctt
     3841 cagaatagta tttcgccaat ggtttttatt gaagaggtga ttgtgttatg atagtctaaa
     3901 ataaaattga tttaatagag taaatggaga atcgttacat gaaacatttt tttgcaggaa
     3961 ttggtgagat aaaacttgtt ggctacttat tgtatatatg tgtaggacta gcccctcttt
     4021 ttcatatata tgtcataggt tcggaactga gttttgtgaa aatagtgtta tctattttgg
     4081 gagttatatt tgtaagtatg ttaactattg ctcgaattta tcggactttt ctataaagaa
     4141 tagtttggac ttaaactgta tctaaaaaca gaggttggtc gattatcagc ctctttcttg
     4201 tcgttgaaaa gagtgagata tattgacttt tgaaaaaaag atgtcataat tgagttggga
     4261 taaacctaaa agtaatatag tagattgaat ctggaatagt ccgttatgac tgttaaaata
     4321 tttctagaaa ttaatttgac tttcctaatc gatttgttca catcttgttt caatctacta
     4381 tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatagt agtaagcaca
     4441 ctatgtggct tggcagagct aaaaactgtt cccttgcgat aagcctaata agcacaacat
     4501 agggagttag agaagccgac tctaatcaac cactttgggc aatagtgaga actgccccgt
     4561 gcttttttat tttgagaaaa tatggagttt gtcgttgaaa ttacttgatt gtattttgga
     4621 ctatcaagaa agattcaatg gaaaaacatg tcaagtatca acgaattata agtatttaga
     4681 gattttcaaa gtgaattttt gtttgactga tttacatcat ttatttgact tatacaaaat
     4741 cacacgagat tatgctagtc aaacaaaacc tgctattcaa gatggtgttt ttattttaga
     4801 agattttaga aatatcctat gtacaatgat gtaatcgaaa ggatatcttt atgtgagttt
     4861 atcggcgata tcttctatat ctaagctagc aagttgttgc atcgtagcta aggatttatc
     4921 taaaaatact atgaaattgg acgtcatatt ttttgaggat aaaaataaaa gatccgcagt
     4981 tttaggttta cgaagagaca aaagcggagt atttaaacca gttactctac attttacaag
     5041 cgctaagaaa tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag
     5101 attgtccgca ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa aacaagctct
     5161 ctcatcggaa atgtttttat aggaatgaag gaagatgatg ctatgtttaa aaagagaatc
     5221 gaaaagggca aaagtagtgt ctttatcttt ttggagtaga agcttatgat atagaaattt
     5281 gtaataaaaa tgtaatataa aacatttgac aaatatttac ggggggagta tacttaatat
     5341 aagtatagtc taaaaatgac tatcagaaaa gaggtaaatt tagatgaata agaaaaaaat
     5401 gattttaaca agtctagcca gcgtcgctat cttaggggct ggttttgtta cgtctcaacc
     5461 tacttttgta agagcagaag aagctcccgt agctagtcag tctaaagctg agaaagacta
     5521 tgatgcagca gtgaaaaaat atgaagctgc taagaaggaa tatgaggacg gaaaagctgc
     5581 tcagaaaaag tatgaagatg atcagaagaa aactgaggag aaagcggaag aagaaagaaa
     5641 agcttctgaa gaagaacaag ctgcaaatct gaaatatcaa caagagttgg ttaaatatat
     5701 acgtgaaaat gatccaacaa aaaaagctga agctaagaaa gcaatggatg aggctgagaa
     5761 agagtataag aaaaaacaaa cggaatttgc tgaagttcgt gcaaaggtaa ttcctagcgc
     5821 ggaagaatta aaaaagacta gacaaaaagc agaagaggct aaagcaaaag aagcagaact
     5881 tactaaaaaa gtagaagaag ctgagaaaaa agttactgaa gccaaacaaa aagtggatgc
     5941 agaacatgct gaagaagtcg ctcctcaagc taaaatcgct gaattggaac atgaagttca
     6001 gaaactagaa aaagctctca aagagattga tgagtctgat tcagaagatt atgttaaaga
     6061 aggtctccgt gctcctcttc aatttgaatt ggatgttaag caagctaaac tatcaaaact
     6121 tgaagagttg agtgataaga ttgatgagtt agacgctgaa attgcaaaac ttgaaaaaga
     6181 tgtagaagat ttcaaaaact cagacggtga gcaagctgga caataccttg ctgcagctga
     6241 agaagactta gttgctaaaa aagctgaatt agaaaaaact gaagctgacc ttaagaaagc
     6301 agttaatgag ccagaaaaac cagctgaaga aactccagct ccagcaccaa aaccagagca
     6361 accagctgaa caaccaaaac cagcgccggc tcctcaacca gaaaaaccag ctgaagagcc
     6421 tgagaatcca gctccagcac cacaaccaga gaagtcagca gatcaacaag ctgaagaaga
     6481 ctatgctcgt agatcagaag aagaatataa tcgcttgacc caacagcaac cgccaaaagc
     6541 agaaaaacca gctcctgcac cacaaccagg ttggaaacaa gaaaacggta tgtggtactt
     6601 ctacaatact gatggttcaa tggctacagg ttggctacaa a
//
LOCUS       DAVBED010000078         6447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBED010000078 DAVBED010000000
VERSION     DAVBED010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.078"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQ547_001971"
     CDS             222..422
                     /locus_tag="VQ547_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543766.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQ547_001972"
     CDS             447..863
                     /locus_tag="VQ547_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543767.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ547_001973"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ547_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2543768.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ547_001974"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ547_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2543769.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQ547_001975"
     CDS             2490..3881
                     /locus_tag="VQ547_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2543770.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ547_001976"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ547_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2543771.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQ547_001977"
     CDS             4949..>6447
                     /locus_tag="VQ547_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2543772.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVBED010000079         6252 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBED010000079 DAVBED010000000
VERSION     DAVBED010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.079"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQ547_001978"
     CDS             complement(7..1221)
                     /locus_tag="VQ547_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2543773.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQ547_001979"
     CDS             complement(1377..1670)
                     /locus_tag="VQ547_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543774.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQ547_001980"
     CDS             1832..2284
                     /locus_tag="VQ547_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2543775.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQ547_001981"
     CDS             complement(2319..3707)
                     /locus_tag="VQ547_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2543776.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQ547_001982"
     CDS             3773..4735
                     /locus_tag="VQ547_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2543777.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQ547_001983"
     CDS             complement(4732..4923)
                     /locus_tag="VQ547_001983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543778.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ547_001984"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ547_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2543779.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT         1827 a         1457 c         1186 g         1782 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa ag
//
LOCUS       DAVBED010000080         6187 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBED010000080 DAVBED010000000
VERSION     DAVBED010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.080"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ547_001985"
     CDS             complement(119..751)
                     /locus_tag="VQ547_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2543780.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ547_001986"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ547_001986"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2543781.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ547_001987"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ547_001987"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2543782.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ547_001988"
     CDS             2567..3139
                     /locus_tag="VQ547_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2543783.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..4054)
                     /locus_tag="VQ547_001989"
     CDS             complement(3191..4054)
                     /locus_tag="VQ547_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543784.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            4520..4858
                     /locus_tag="VQ547_001990"
     CDS             4520..4858
                     /locus_tag="VQ547_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2543785.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            4836..5195
                     /locus_tag="VQ547_001991"
     CDS             4836..5195
                     /locus_tag="VQ547_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543786.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            5214..5426
                     /locus_tag="VQ547_001992"
     CDS             5214..5426
                     /locus_tag="VQ547_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543787.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            5841..5909
                     /locus_tag="VQ547_001993"
                     /pseudo
     CDS             5841..5909
                     /locus_tag="VQ547_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            5889..>6187
                     /locus_tag="VQ547_001994"
     CDS             5889..>6187
                     /locus_tag="VQ547_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2543788.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
BASE COUNT         1901 a         1050 c         1311 g         1925 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaggtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacagtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctccagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggtttaata gaattgtcat tcgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aggcgttgca atatttttcc agtgatgaga tggaggtatt
     3541 caatgggaaa actgaaaaga atggtattga ggatttttag atcactctca taccatgtat
     3601 cttgtttttc aatttttttc caaagttttt tgacaacctg ttctgcgtgt tttgatagtt
     3661 cccctgcccc gtgttgacgg agataaataa caacttcaag catatctctg atttcttcta
     3721 tagggagatc gtggtgggtc ttgaggtagt cttggcattt ttgaaataaa ttgacaagat
     3781 cgctggtccc gataatggaa cgcatattga gataggtttg cataatctct gtgcgttgac
     3841 ttggttgata aagttgacag atatattcaa actcttcaaa actcatattg atttgacgga
     3901 gaagaaattc catattttca tattttgggg ttgtcttgcc actttcgatt tttgataagc
     3961 tggttcttga gagaacaccc ccacagacct cttcttgggt cagccccttt gactcacgta
     4021 tttctttata gacctttccg aaatcataac gcatgatttt ctcctttctg tgaaaaaagt
     4081 taacaaacaa taaaattttg ttaaaaatat tgtatcatag caatgtaaaa agtaaaaaag
     4141 aaagtcgaaa taaatttgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg
     4201 tatgatgtag gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat
     4261 tctagtatgt attatatcat tgattagtct ggccataatc tttccatggg gctggtcgat
     4321 ataatgtaag ggagcttgag ttgttaaagg aggcttagtc cttggacaaa aatctgctgt
     4381 actacaatgc ttggaaagat atcaagaaca aagaatgata cgattgaaaa taaactgatt
     4441 caagaactac tgggcagtga ttgaggtttg ggtgacatca aagaaaagtt agattaattc
     4501 taaagaattg agtatttcta tgttaaaaaa atatccttgt acgatgcaac atgatcagtc
     4561 agattgtgct gcggcagttg tttcaacagt tcttttatct tacaaaaagg aactatcaat
     4621 catgaagatt cgggaaatta ttggtacaga catgtatgga acgactgtca gtggtattgt
     4681 ttcaggtctg aataagttga attttacagt aaaagctgtt cgagtagcac tggaagattt
     4741 gactccaaaa ttaacatttc ctgcgattct tcaagttaag aatgatttag gtcaaaatca
     4801 ttttgtggta ttacatagta taaaggagaa aataaatgga actcgtatta ccaaataatt
     4861 atgttgtgat tgatgaagaa gagatgatgt accttgatgg gggggctata tatataccca
     4921 ggtgggcaat tacaggagcc attactggtg cagcatatgc agcattagca gcagcaggag
     4981 gtggaggcct tcaactagtt cttgcatctt atggattacg ctccgcactg gtagctggga
     5041 ttgttaaagg tttaggagta ttaggaattc atattggaaa tgcttttgca aatactgtta
     5101 ttagaagtat tgcatctgct ggaattggtg ctggagctga ttggatttta ccaatattat
     5161 tgatggctgg gatgggcgac gtgataatca attgagaata ggataatagt attatgatgg
     5221 ttgttttaat ttcagttatt gttgcattcc tgtaccataa aattacagag tatgtcaaca
     5281 acaggaaaat tgatattgtt atttttctat cattgctgat ttctcatttt atttggaatt
     5341 actatttttt accaattgaa atattgatag caatcagtgg agcaaattta ttattaagtt
     5401 ttttaaaaaa attacagatt aaataatatt attccatatg acatatcaac taggtcatta
     5461 gattttattg aagatataaa ttaaaaacga ggttgggaaa aaactcaatt tgaaagtgaa
     5521 attgagtaaa tttttctatt atataacgca tattatcaag atttttgaac acctgataat
     5581 atgcactttt cttattttaa agattttttg cctttcttca tttcttgaat gaattggaga
     5641 gatgacttta tttaggtgtt tgacattact atagatagga tttagcagta ctaatatgaa
     5701 ctcatattat aggtgcagac ttaaattttg gaagcaagct aaaggatatc ttatctaggt
     5761 aactaagtgc tataaacaaa gtcaacgatc acttgttagg aaacgatcct aactatgctt
     5821 aataaaaaag gagaaaataa atggaactcg tattaccaaa taattatgtt gttcttgagc
     5881 aagaagagat gatgtatctt gatgggggtg gtgttggttg taactggtgg aacaaacgtg
     5941 ataatattgc tgcagctgca gtttctggag ggatgtcagt ataccagaca tatgccatta
     6001 aaaagttaat tgctaatcgt ggtatgatga gccgagtcgt tagaagtgct ataacaagat
     6061 atattggtgg agttagtatg gcaactatta ctaatgctct taatattgcg gctactgttg
     6121 ctgaagtttt ctcattagga ggagccattg catatggttt agatatcgta gacggtaaat
     6181 ttgatgg
//
LOCUS       DAVBED010000081         6052 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBED010000081 DAVBED010000000
VERSION     DAVBED010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.081"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..501)
                     /locus_tag="VQ547_001995"
     CDS             complement(<1..501)
                     /locus_tag="VQ547_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543789.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSF"
     gene            complement(491..688)
                     /locus_tag="VQ547_001996"
     CDS             complement(491..688)
                     /locus_tag="VQ547_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543790.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(692..1276)
                     /locus_tag="VQ547_001997"
     CDS             complement(692..1276)
                     /locus_tag="VQ547_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543791.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1684..2109)
                     /locus_tag="VQ547_001998"
     CDS             complement(1684..2109)
                     /locus_tag="VQ547_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543792.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2102..2596)
                     /locus_tag="VQ547_001999"
     CDS             complement(2102..2596)
                     /locus_tag="VQ547_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543793.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(2642..2848)
                     /locus_tag="VQ547_002000"
     CDS             complement(2642..2848)
                     /locus_tag="VQ547_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543794.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(2835..2996)
                     /locus_tag="VQ547_002001"
     CDS             complement(2835..2996)
                     /locus_tag="VQ547_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543795.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3361..4317)
                     /gene="lytA"
                     /locus_tag="VQ547_002002"
     CDS             complement(3361..4317)
                     /gene="lytA"
                     /locus_tag="VQ547_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2543796.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(4693..6045)
                     /locus_tag="VQ547_002003"
     CDS             complement(4693..6045)
                     /locus_tag="VQ547_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2543797.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         1928 a         1277 c          946 g         1901 t
ORIGIN      
        1 gaagctgacg tggtttgaag agattttcga agagtataaa ccacaattac tcaataccga
       61 atacccctga atggtttctt tttcatgcac caatatatta taataatctt catccaataa
      121 taaggctgat aaactagcat cttggtcaaa atgtaaggga atttctcgac cgtccttctt
      181 taatggatat tctggtaaga tactaaatag ttcaatcata gaaggaaact caggattagt
      241 tgttgtaaat cgaaaaagct gcgctttctc atctttctga cttccttgat actctcccaa
      301 ttctaaaaaa tgattcaagg tagtataaaa ttccttattt tttacttcat aaatgatgac
      361 catatcataa tcttttgttg tgcgactttt aaatccttgc gaatccaata cgatagaggt
      421 agcagttccc ccaatcagaa cataatagtt ctgaaaatcc gcaaacattt cttgaaaaat
      481 aactttcgta ttagctggca tcatcttctc ccagatactg taatatcata ttttctagtg
      541 cttcactctc ttcctctata cgtgggtcat catcatcttt taaggtcaaa taaagagaaa
      601 tcggatctac aaattgttta tcatgattat ttttaaaatc attccaaaac tcagatacaa
      661 aaggacgata tttccatatc tctagcatct ttcattttaa aacatgctga gaaagtggca
      721 aggataactg attgaatttt ctctgccata tgacatagct agtattttca tccgtttcag
      781 ctaaaaaagt tgaatgcgac aaagcataag caccaccata tagaaggtta gaaacagatt
      841 ttatctgctt tatatcgcca tctggcaata aaaaggcaat ccacgttaat tgttcgctag
      901 gtgttaattc cttagggatt tcagtatcat tcgcattgag tactagtccc aatggaggga
      961 agaagaggtt tcccttaaag tctacaaacg gaactctagc ttgaagtaat tgcttttttt
     1021 cactgtctga taacttcgaa aacaccaaaa caacatccat attggctttt tcacccatag
     1081 tgcgagcctg agtaacaaat gaactcaaac tcccccttct cttttcttta atcaataaaa
     1141 atgattcctt atgaaaagtc atttgagtat actcaaacct ttttacaaaa ctgattggta
     1201 aagtcaaagt cagttcctca atactgacat caacataaaa ggattgaaaa attgacatta
     1261 tctttttgac attcatgttt tttccttatt ctatcatttt tattatattt tatcattcgg
     1321 tataataaaa tataagtttt ttgataaaat aaccaaaaac tactcgctat cccctctcac
     1381 attaccctac atatcgtttg acatgcgact gatagttcag gaaaacttca aggagaactt
     1441 ttctctcatc cactatgcag gacttactat ttcacttcta ctcctatagg ctcaatttga
     1501 cacttttctt tttcgaattg ctcatatgcc tcctgaatag tgagttcgat ttatccaaat
     1561 ttatttttgt ctattttgat gaatacttcc acgaagatag tctgaaaatg aatttgcacc
     1621 aattttcctt ctctttttaa gcatattatt ccagatatga ttgccctctt gttcagtaat
     1681 aaattacgct ttaaacgctt caatcagtat atctcctgtt gtcatatgtt ctaaagaaaa
     1741 ttcttctaca tatggtttaa catctcttag gttattactt cctaatatcc cattatgctt
     1801 tttcgctaag aaaatagaag tcgcttctcc cttaccaata atcttgttac tatcataatt
     1861 tcttgttaaa tctctatata atgcgtattc ttcagttcca atgtctatgc tcacaatctc
     1921 agctgaaccc ttagttacca actggtctat cctagatttt aaatggggaa ttgtaggtat
     1981 attgatttca tcatacacct cttgtggaat aacaatttta cccgaataga gcttttctaa
     2041 aagatgttca gtgccaaccc ataaaaatgc tgaaatacaa tctgcatcaa taaatacacg
     2101 actagtcaaa cgacaactcc ccctcttcat ctagcccata tacaatatca tatctgaaag
     2161 catctagtaa cagttcctca tacttccctt gcgaaattct gttattttct aaaagttgtt
     2221 cagtcgattt aatatagtgc cctaatacca tttccttttt actttctgac aaaggacgat
     2281 ataaacttgt atcatagcct aatcttgaag ctgtctctat aacactaata tccatatttt
     2341 taatttcttc tgcatcaagg tatccatcat ttctcaatct atataacata gctttatgac
     2401 tgataccata aaactgaccc aattttataa tatcttctac ttcaagatga gttctattgg
     2461 cattttctct gatttcctca accatcctat acagtgaaga tgggaaaatt aaaaaataag
     2521 aagcaaactg atccgctttt ctttcagttt catctccttc accaatcaag ataagactga
     2581 ctgaactctt cttcacctca tcataataaa gatgatacag tccatgtgct aaagaaaatc
     2641 tttaccttcc taatggcatg tctgaattga ctgcaatgag actgaactga gttcctttat
     2701 aacagactcc gctaatattc tttccgagtc cataaaatac cagcgtcaaa ttttctatct
     2761 tttgtaccaa tttaaaaata tctatcggcg attcaccatc agctcccaac ttttttctaa
     2821 gatttgaagc tttattactt aaatccattc gtgatattcc tttcaccttt ttccattttg
     2881 gcaatcatgc tttgattcaa agacaaatac tcagcaatct tatcttgagt aagatttgaa
     2941 gatattctaa gttcttttat tctttttcca acatcacata catttatcat attcatacac
     3001 ctctcataaa aagaatagca cattcttgtc ataatttttt aaataaaaaa attatgacaa
     3061 aacaaggaag caatttattg atgctactta aaaatctaaa attgatgata ttaaacctat
     3121 ttgatgagtt cctatcaaaa atcgtatctt caacctcaaa acagtactta aagctatccg
     3181 actcggttta cattgtcaaa tttagatttt atttgagcat aactttctag tttgcttttt
     3241 gatttttgtt taatatagta acaaaaattg aaggaaatat ctccacaaga aaacgcatac
     3301 tattaagctt tttcaagacc taataatatg cgctgttctg atttgaaaga cattccatta
     3361 ttattttact gtaatcaagc cttcaggctc tactgtgaag tctggcttgt ctgccagtgt
     3421 tccgtctggt ttgaggtagt accagcctgt tccgtccgct gactggataa aggcatttga
     3481 taccatggcg ccttctttag cgtctaagta gtaccaagtg tccttgtact tgacccagcc
     3541 tgtcttcatg gcaccttctt cgttgaaata gtaccactta tcagcgattt tcttccagcc
     3601 tgtagccatt tcgcctgagt tgtcgaacca gtaccagttg ccgtctgtgt gcttcctcca
     3661 gcggtctgca agcatatagc ctgaactgtc aaagtagtac caagtgccat tgattttctc
     3721 aaacttgtct tttggataag agccgtctga atgtacgtac cagtagccag tgtcattctt
     3781 ctgccagcct gtttcaatcg tcaagccgtt ctcaatatca tgcttaaact gctcacggct
     3841 aatgccccat ttagcaagat atggataagg gtcaacgtgg tctgagtggt tgtttggttg
     3901 gttattcgtg caatactcgt gcgttttaat tccagctaaa ctccctgtat caagcgtttt
     3961 cggcaaacct gcttcatctg ctagattgcg taagagttcg atataaaggc ggtagtccgt
     4021 catgaactct tctttggttg aatggctttc aatcagttca accgctgcat aggtctcagc
     4081 attccaaccg cccccaacgt cccaggcacc attatcaaca ggtcctacct gcatgatgca
     4141 accgttccca acaatgtgcg agaaaaaacc taattctggg tctttccgcc agtgataatc
     4201 cgcttcattc tgtacggttg aatgcggatt cccagttgag tgtgcgtgta cttgcctata
     4261 tggttgcacg ccgacttgag gcaaatctgt tcttaattta ctcacattaa tttccatatt
     4321 ctactcctta tcaattaaaa caactcattt tttacaatcc agaaccagaa actcctttat
     4381 ttctacctta caaagaagac aatcttagtc acgattaagc ttgtagatag aacctcaaaa
     4441 cgcactattt tgacactgta aataggactg acaaggtctg cattctatct acaataacac
     4501 cccagactaa aaagcttttc aaaagtatat ttttacagtc tctatatgtc cttttcataa
     4561 atactatact ttattatatc acataaaaga agtcaaaagt ctgttaaact attttcaaca
     4621 ccaaactaaa gaagagaaca caagtttttt cgatgttcac tagaggaaat ggattttatt
     4681 cagtaaatcc aactaggatt gcactttggt tgccaaaatt gcctttcctt cttttatcaa
     4741 gggatgacgg aatagtgaga agtacagttg aactgtcatg gcaacccaga taagaggttc
     4801 acaaaggata acacccttat atcctgccca aggaataatc aaaaccacaa aaacgatttt
     4861 tccgattagt tcaataaagc tagaaactag aggaaggatc ttctgcccca agccctgcaa
     4921 gcaattgcga taaatcaaca agaggctcaa aatgggataa aaggctgaac tgatttgcag
     4981 atagagactt ccattttcta tcaagtaacc atctgtcgaa ctagccaaga aggaaaccaa
     5041 ggctggactg gcaaaaaaga ggaaaataca aacaaaaact gcccaggata tacttaaacg
     5101 actgccgatt cgaagacctt gaacaatgcg gtcaggtcgc ttagctccta gattctgaga
     5161 agcaaaggtc gtcattgatg cagaaatagc ggtcatagga agaagggcaa aggtcataat
     5221 gcgtcgagct gccgtctggg cactaataat cactgcacca aatgtattaa cagaaaactg
     5281 taaaatcaca ctgccgatag atacaattga actcatcaag cccatagcca aaccttgctc
     5341 caagagatcc gcgtacaagc ttttgtccca tttgaaatgt ttaaactgtg gcaagagttc
     5401 tggcacactt ttacgaatat aataaaagca gagaaccgct gataaacctt gcgaaataat
     5461 ggtagcaagt cctgcggatt gaactcccag atgcaattgc gtaataaaat agagatccag
     5521 aaccacatta accaaggcag agaaaatcag aaatcccagg gctgctagac tgtcaccaat
     5581 agaccgcaac aagcctgcaa aaagattata agcaaagctg acacctacac aggtcacaat
     5641 catagaaata tattgataag attgaggaag aatttctgca ggagtatcta agtattgcaa
     5701 gagatgatac aagccaagaa agcccagcaa cataactaga atgctcaaaa gagcacctaa
     5761 aatccaagta gctgctactg cttccttgat tttagtgaaa ttccgagccc cataataacg
     5821 agcaatgaca atccccatgc cattgccaac accaagtgta aaacctacaa tcaggtcaaa
     5881 aatcgctgtc gtcgctccta ctgcagccaa ggattcttga ccaagaaatc gtccaacaat
     5941 caagacatca gcagtgttat agagctgttg aaaaatattt gatagcaaaa ttggaaaggt
     6001 gaagcttaag agcgagggaa gaatcggacc atgtatcagg tccactgttc gt
//
LOCUS       DAVBED010000082         5096 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBED010000082 DAVBED010000000
VERSION     DAVBED010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.082"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQ547_002004"
     CDS             182..658
                     /locus_tag="VQ547_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543798.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQ547_002005"
     CDS             complement(1332..1724)
                     /locus_tag="VQ547_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2543799.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQ547_002006"
     CDS             complement(1702..2163)
                     /locus_tag="VQ547_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2543800.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQ547_002007"
     CDS             complement(2126..2386)
                     /locus_tag="VQ547_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543801.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQ547_002008"
     CDS             complement(2391..2819)
                     /locus_tag="VQ547_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2543802.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQ547_002009"
     CDS             complement(2788..3114)
                     /locus_tag="VQ547_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2543803.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQ547_002010"
     CDS             complement(3116..4132)
                     /locus_tag="VQ547_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2543804.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQ547_002011"
     CDS             complement(4080..5021)
                     /locus_tag="VQ547_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2543805.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
BASE COUNT         1524 a         1097 c          886 g         1589 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttct
//
LOCUS       DAVBED010000083         4871 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBED010000083 DAVBED010000000
VERSION     DAVBED010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.083"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            191..409
                     /locus_tag="VQ547_002012"
     CDS             191..409
                     /locus_tag="VQ547_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2543806.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1454..2446
                     /locus_tag="VQ547_002013"
     CDS             1454..2446
                     /locus_tag="VQ547_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2543807.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2448..3266
                     /locus_tag="VQ547_002014"
     CDS             2448..3266
                     /locus_tag="VQ547_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2543808.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3268..4053
                     /locus_tag="VQ547_002015"
     CDS             3268..4053
                     /locus_tag="VQ547_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543809.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4092..4370
                     /locus_tag="VQ547_002016"
     CDS             4092..4370
                     /locus_tag="VQ547_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2543810.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4355..4552
                     /locus_tag="VQ547_002017"
     CDS             4355..4552
                     /locus_tag="VQ547_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543811.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1399 a          796 c         1022 g         1654 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt catttagtat aacagattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga tattttgaaa taaatataga
      241 tgaaaatatc accgatattc tatacgtaaa tggtactgct attctttatc attatttacg
      301 ttctattgtt tcaatagttt cggcaattga tagcagtgaa gcaatgttgc tacctaccat
      361 taatgtttta gagttactag ataaatctca accttttgaa gaagaataat ttattagctc
      421 actaaattga gggtaaggaa aagtaaaatc agtaagaaaa atgtcttgca ttatacagca
      481 accttttggg aatgagtaga tggattgaat aaaattttat taagagtgga tgatttatct
      541 gtagattatt attggacagt tagtcttgaa gtagtctaag aattaggtta taatcagtag
      601 aatccttgct aataatgagg aggttagttt atgtatagta gactgaatct aaaatagtac
      661 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttctca
      721 tcttatttca atccgctata tattatggta tcgaatcttc atcagaatga taaaattaat
      781 caattgatat ctgattacaa acagaatatg aaagcttttt atatcactat tgaaaaattt
      841 atacgagatg atgaaagcct taagtgttat tttataaagg ttatttcaag tcgttccaag
      901 gtaacaagtc tagatcagat tgaagctgat aaaacgatac aaagaaaata ttcaagtgag
      961 ctaaaaaaat ttattggatt ttataatgag attatttgtg aggaaaatag tttcctacat
     1021 gtacgaaaga ggtggtcgag ttggtttagg tagtcgatgc gtgagttgat aattctcagg
     1081 gtatggactt ctttttcatg aatgaggtaa aagagcaggt attgtttaga gacaatcatt
     1141 ctgagcatat tttctggata gagggagtat ccgattttat gatcaaagtt aataccgccc
     1201 tctggtgaga agatgagtag gttggtaatt taaactatta aacagaattt ttgattaaaa
     1261 gtattatttt atgagagaaa tcctaatttc acaatccata ggcaaactct tgcatttcgt
     1321 tttttattgg actataatag gttggtataa agccttttgt agtaataaaa tgtagaaggt
     1381 gtagaaagca aggatttaga atatttgtag ttaaaaacac aatgttgcta ttccttacga
     1441 tagggagata gatatggcaa tgatagaagt ggaacatctt cagaaaaatt ttgtgaagac
     1501 tgttaaggaa ccgggcttga agggggcttt gcgctccttt attcatcctg aaaagcagac
     1561 ctttgaagcg gtcaaggatt tgacctttga ggttccaaaa gggcagattt taggatttat
     1621 cggggcaaat ggtgctggga agtcgacaac cattaaaatg ctgacaggaa ttttgaaacc
     1681 aacatctggt ttttgtcgga ttaacggcaa gattccccag gacaatcggc aagattatgt
     1741 caaagatatt ggcgtagtct ttggacaacg cacccagcta tggtgggatt tggctctgca
     1801 agagacctac actgtcttaa aagagattta tgatgtgcca gactcgctct ttcataagcg
     1861 tatggacttt ttgaatgaag tcttggattt gaaggacttt atcaaggatc ccgtgcggac
     1921 tctttcactg ggacaacgga tgcgggcgga tattgcggcc tccttgctcc acaatcccaa
     1981 ggttcttttt ttagatgagc cgaccattgg tttggacgtt tcggttaagg ataatattcg
     2041 tcgggcaatt actcagatca atcaagagga agaaactacc attcttttga ccactcacga
     2101 tttgagtgat attgagcaac tttgtgatcg gattttcatg attgacaagg ggcaagagat
     2161 ttttgatgga acggtgagcc aactcaagga gacctttggt aagatgaaga ctctctcttt
     2221 tgaactgcta ccaggtcaaa gtcatctcgt ctctcactat gacggtctgt ctgatatgac
     2281 cattgataga caaggaaaca gcctcaacat tgaatttgat agttctcgct accagtcagc
     2341 tgacattatc aagcaaaccc tgtctgattt tgaaatccgc gatttgaaga tggtggatac
     2401 ggatattgag gatattatcc gtcgcttcta ccgaaaggag ctctaggatg atcaaattgt
     2461 ggagacgtta taaacccttt atcaatgcag gggttcagga gttgattact taccgagtca
     2521 actttattct ctatcggatt ggcgatgtca tgggggcttt tgtggccttt tatctctgga
     2581 aggctgtctt tgattcttcg caagagtctt tgattcaggg cttcagtatg gcggatatca
     2641 ccctctacat catcatgagt tttgtgacca atcttctgac tagatccgat tcgtccttta
     2701 tgattgggga ggaggtcaag gatggctcca ttatcatgcg tttgttgcga ccagtgcatt
     2761 ttgcggcctc ctatcttttc accgagcttg gttccaagtg gttgattttt atcagcgttg
     2821 gccttccatt tttaagtgtc attgtcttga tgaaaatcat atcgggtcaa ggtattgtag
     2881 aggtgctagg attaactgtc atttatcttt ttagcttaac gctcgcctat ctgattaact
     2941 ttttctttaa tatttgcttt ggattttcag cctttgtgtt taaaaatctt tggggttcca
     3001 acctacttaa gacttccata gtggctttta tgtcggggag tttgattccc ttggcattct
     3061 ttccaaaggt tgtttcagat attctctcct ttttgccttt ttcatccttg atttatactc
     3121 cagttatgat cattgttgga aaatacgatg ccagtcagat tcttcaggca ctccttttgc
     3181 agttcttctg gctcttagtg atggtgggat tgtctcagtt gatttggaaa cgggtccagt
     3241 cctttatcac cattcaagga ggttagtatg aaaaaatatc aacgaatgca tctgattttt
     3301 atcagacaat acatcaaaca aatcatggaa tataaggtgg attttgtggt tggtgtcttg
     3361 ggagtctttc tggctcaagg cttgaatctc ttgtttctca atgtcatctt tcaacatatt
     3421 ccattcctag aaggctggac ctttcaagag atagctttca tttatggatt ttccttgatt
     3481 cccaagggaa tggaccatct cttttttgac aatctctggg cactagggca acgcctagtc
     3541 cgaaaagggg agtttgacaa gtatctgact cgtcccatca atcctctctt tcacatccta
     3601 gttgaaacct ttcagattga tgccttgggt gaactcttag tcggtggtat tttattggga
     3661 acaacagtga ccagcattgt ttggactctt ccgaaattcc tgcttttcct agtttgtatt
     3721 ccttttgcga ccttgattta tacttctctt aaaatcgcaa cagccagtat cgccttttgg
     3781 actaagcagt caggcgccat gatttacatc ttctatatgt tcaatgactt tgctaagtat
     3841 ccgatttcta tttacaattc tcttcttcgt tggttgatta gctttatcgt gcctttcgcc
     3901 tttacagcct actatccagc tagctatttc ttacaggaaa aggatgtgtt ctttaacgta
     3961 ggaggtttga tgttgatttc tctggttttc tttgttattt cccttaaact ttgggataag
     4021 ggcttagatt cctacgaaag tgcgggttcg taaaagctaa agtaagacta aaatcaagaa
     4081 agaaacttat gatgtttgta attgaagaag tcaaggatga aaatcaaaaa aaggcagttg
     4141 tagctgaggt tttgaaggat ttgccagaat ggtttggaat cccagaaagc acacaagcct
     4201 atatagaagg aaccacgaca ctgcaagttt ggaccgccta tcaggagagt gatttgacta
     4261 gatttgtaag cttatcctat tcgagtgaag attgtgcaga gattgattgt ctcggcgtaa
     4321 aaaagcttat caaggtagaa aaattgggag ccaattgctt gctactttag agagtgaagc
     4381 tcgtaaaaaa gttggttatc tgcaggtcaa aacagtggca gaaggttcta ataaagatta
     4441 tgatcgaaca aatgactttt atcgaggtct tggctttaaa aagttagaga tttttcctca
     4501 actatggaat ccgcaaaatc cttgtcagat tttgattaaa aagcttgaat aatattactt
     4561 gacatctatt ctcagagtgc catactgtaa gtgtaatcgc cgatttagct cagttggtag
     4621 agcaaggcac tcgtaaagcc taggttatag gtagataaac gactgaggag ttgaaaaaat
     4681 agataggtag aagataaccg ttaagcctta ttcttagcgg ttatttatat tgtttaatag
     4741 cgctgatatt tcatcaatta tgcctgtttt cgtgtttctg gtagttgttc aagtttattg
     4801 ctactatttt tgatggtatg aatgtgctta taatgtatcc cggttaacga aagttttgga
     4861 cttatactct t
//
LOCUS       DAVBED010000084         4610 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBED010000084 DAVBED010000000
VERSION     DAVBED010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.084"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            51..1596
                     /locus_tag="VQ547_002018"
     rRNA            51..1596
                     /locus_tag="VQ547_002018"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1648..1720
                     /locus_tag="VQ547_002019"
     tRNA            1648..1720
                     /locus_tag="VQ547_002019"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1681..1683,aa:Ala,seq:tgc)
     gene            1845..>4610
                     /locus_tag="VQ547_002020"
     rRNA            1845..>4610
                     /locus_tag="VQ547_002020"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1271 a          950 c         1378 g         1011 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta
      301 gctagttggt gggataacgg ctcaccaagg cgacgataca tagccgacct gagagggtga
      361 tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc
      421 ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat
      481 cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg
      541 tatcttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc
      601 gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt
      661 taaaggctgt ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg
      721 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc
      781 gaaagcggct ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      841 attagatacc ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg
      901 gggtttagtg ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      961 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
     1021 gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt
     1081 tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
     1141 tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca
     1201 ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg
     1261 ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg
     1321 tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct
     1381 acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg
     1441 gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta
     1501 accgtaagga gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt
     1561 agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg
     1621 gtcttgttta gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt
     1681 tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt
     1741 aatgcacatt gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg
     1801 ctgtagtatt aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg
     1861 gcgcacggtg gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc
     1921 cttgggtagc tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt
     1981 agtacctgtt acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat
     2041 ctaagtagct gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg
     2101 caggagggca aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa
     2161 gattatagaa gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa
     2221 tagtctttgt acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc
     2281 tgggaggacc atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt
     2341 gagggaaagg tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct
     2401 acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag
     2461 ttacgttatg atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat
     2521 agggcgcctt agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg
     2581 aaggtgcggt aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga
     2641 cttgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag
     2701 ctttagggct agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg
     2761 tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt
     2821 cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg
     2881 tcccaaaata attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag
     2941 cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg
     3001 ccgaaaatgt accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg
     3061 taggagagcg ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag
     3121 tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag
     3181 gtttccaggg gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg
     3241 tgtatccgat ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg
     3301 cagtaggcta actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg
     3361 agtcaaatgc ttatatctgt aacattgagc tgtgatgggg agcgaagttt agtagcgaag
     3421 ttagtgacgt cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg
     3481 caaaccgaca caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag
     3541 gaactcggca aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc
     3601 agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg
     3661 atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc
     3721 gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc
     3781 gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc
     3841 tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga
     3901 cggaaagacc ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca
     3961 ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac
     4021 tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg
     4081 acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc
     4141 ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga
     4201 gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg
     4261 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt
     4321 cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc
     4381 ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc
     4441 gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta
     4501 gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg
     4561 ctgggtagct atgtagggaa gggataaacg ctgaaagcat ctaagtgtga
//
LOCUS       DAVBED010000085         4552 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBED010000085 DAVBED010000000
VERSION     DAVBED010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.085"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQ547_002021"
     CDS             complement(112..549)
                     /locus_tag="VQ547_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2543812.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ547_002022"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ547_002022"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2543813.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQ547_002023"
     CDS             3520..3873
                     /locus_tag="VQ547_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2543814.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQ547_002024"
     CDS             4088..4204
                     /locus_tag="VQ547_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2543815.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQ547_002025"
     CDS             4197..4430
                     /locus_tag="VQ547_002025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543816.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVBED010000086         4546 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBED010000086 DAVBED010000000
VERSION     DAVBED010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.086"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQ547_002026"
     CDS             <1..141
                     /locus_tag="VQ547_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543817.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQ547_002027"
     CDS             complement(134..307)
                     /locus_tag="VQ547_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2543818.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQ547_002028"
     CDS             complement(465..2072)
                     /locus_tag="VQ547_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2543819.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQ547_002029"
     CDS             2225..3709
                     /locus_tag="VQ547_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2543820.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQ547_002030"
     CDS             3804..4286
                     /locus_tag="VQ547_002030"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2543821.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1317 a         1046 c          859 g         1324 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaaaatc gagtagggga taatctctag cccctctcac
     4321 accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca
     4381 aggtaataat ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca
     4441 cgtttaagta ccgacttctg agctactata gtggattgaa actagaatag ttcacctctg
     4501 cttctaaaac attgttagaa atcgatttga ctatcctgat cgattt
//
LOCUS       DAVBED010000087         4437 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBED010000087 DAVBED010000000
VERSION     DAVBED010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.087"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..118
                     /locus_tag="VQ547_002031"
     CDS             <1..118
                     /locus_tag="VQ547_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2543822.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            120..965
                     /locus_tag="VQ547_002032"
     CDS             120..965
                     /locus_tag="VQ547_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2543823.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            975..2294
                     /locus_tag="VQ547_002033"
     CDS             975..2294
                     /locus_tag="VQ547_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2543824.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2502..2574)
                     /locus_tag="VQ547_002034"
     tRNA            complement(2502..2574)
                     /locus_tag="VQ547_002034"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2539..2541),aa:Lys,seq:ctt)
     gene            complement(2838..4109)
                     /locus_tag="VQ547_002035"
     CDS             complement(2838..4109)
                     /locus_tag="VQ547_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2543825.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1293 a          809 c          976 g         1359 t
ORIGIN      
        1 tcaacaaggt tttactgatc gtcttgtagg atattctagc tcaatcgctt tagtatttac
       61 aacgttaatt ggtatgatta gcttagtaca acgtcgcgtt ctgaaggagg atgactaaga
      121 tgaaacgatt taaaccaaca acaatcttag aatatattct gttaacttta ttggcaggac
      181 tcttcctttt tcctatggtt tggatggtag tttcagctat gaagccagaa gcggatgttt
      241 ataaaaattt gactagttgg caagccttct taccaagttt aaatcccgct gattggttta
      301 aaccttatca ggaagtattt gagcgcttta gtatttttac atatctaggg aacagcattt
      361 tttatgctgg aacgtttgct attggttcta ttattgtcaa tgcactggcc ggtttcgctt
      421 ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg tttcttactt gctttactta
      481 ttattccagt ggaaactgtg ttaattccac aatttaccat tatcaattcc ttaggtttgg
      541 tcaataatcg tcttgcagtt attattccag gattggcgag tgtatttaat atttacttat
      601 ttaggaattt ctttattgca attccagaag agattcttga gtctgcaaag atggacggag
      661 caagtatcgt tagaattttc tttagaatta tgcttccaat gtctaaacct gcagttgcta
      721 cagttggtgt tttatcattt atttcaagct ggaatgatta tatctggcca ttgatggttt
      781 tgacagattc ttctaaattt tcaatgcagg ttgcaattac aactattaat acaactcaac
      841 cagtttatat caatcaggta atggctgtat taactatttc aacgattccg ttgattttgg
      901 tctatgtagt cgctcagaaa tatattgttc aaggtctggg tggttccgga actggaataa
      961 aataggatat acttatgata aataaaacat ttacagtaga aaaagccaat cgttttatag
     1021 cagaaaataa acatctcgtt aatactcaat ataagcctga agaacatttt tcagctgaga
     1081 ttggttggat caatgatcca aatggatttg tctattttcg tggagaatac catctctttt
     1141 atcaattcta tccatatgat agtgtttggg ggcctatgca ctggggacat gctaaaagta
     1201 aggacttggt gacttgggag cacttgccag tggcacttgc tcctgaccaa gattatgacc
     1261 gaaatggttg tttctcaggc tctgccattg tcaaggatga tcgcctctgg ctcatgtaca
     1321 ctggacatat cgaagaagaa accggtgtcc gccaagtgca aaatatggca ttttcagatg
     1381 acgggattca ctttgaaaag atttcccaaa atccagttgc aactggatca gacttgccag
     1441 atgagttgat tgctgctgat ttccgtgatc caaaactctt tgaaaaagat ggacgctatt
     1501 actccgtagt agctgccaaa cacaaggata atgtgggctg tatcgttcta ctagggtccg
     1561 ataacctagt agaatggcag ttcgaatcca tctttttaaa aggaggagaa caccaaggct
     1621 ttatgtggga atgcccagat tacttcgagt tagatgggaa agattgcctt attatgtcac
     1681 ccatgcgtta tcagcgtgag ggagactcat atcataacat caactcatcg cttttgttca
     1741 cgggtaaggt agattggaga gaaaaacgtt ttatcccaga atcagttcaa gaaattgatc
     1801 atggccaaga cttctatgcg cctcaaacat tgttggacga tcaaaatcgt cgtatcctga
     1861 ttgcttggat gcagacatgg gggcgtaccc ttccaaccca tgaccaagaa cacaaatggg
     1921 catgtgccat gactttacct agaattctaa gattggaaga tggcaaacta agacaattcc
     1981 ctgttaaaaa aggccaatat caaatccaaa tagataaaga ttgtcattac cacttaggaa
     2041 atgatacaga ttatcttgaa tttggttatg acagtaatgc gcagcaagtt tacattgatc
     2101 gtagccatct tattcaaaaa attctaggtg aagaagaaca ggacactagt cgacggtatg
     2161 tagatattga agctaaagaa ttggaagttg ttctagataa aaattccatc gagatttttg
     2221 tcaatcaagg tgaagcaagc ttgactgcaa cttattactt aacggtgcca gctgagctat
     2281 cacgaattga ttaaaaatta agttatttct cctaaagaaa aagttctctt tctaaaatag
     2341 tggaaagagg actttttgtg ttttgggtat ataagcttag tttatggtat ttgtaaaatt
     2401 ggtgttggat tatgatttaa gctagttttc taaagaattt gaaaaaaatt ttatttaagc
     2461 aaaaaaacct tggttccaag gcttttcctg ttgtatttag atgcccccta cagggatcga
     2521 acctgtgacc cacggattaa gagtccgctg ctctgccagc tgagctaagg aggcaaagaa
     2581 aaagctgtat tggtgccgaa acttcacggt ttgtattgaa cccgcgcaat taagcaggtg
     2641 ggcaactcgc tctaactgaa gctgtttccg tgtgagacgg cctacatgct gttagaagac
     2701 ttttgtttcc ctaataatac aaaaaatagt cggtcaacac ttaagtgtga agtcgtacac
     2761 cacagcgttt ctatacttat atgataccac tttttcaaaa aaaatcaaga ggaaagtgca
     2821 attttttgaa aaggatttca gatttttcgc aaacgatcga tagcttcctt tctttgagcc
     2881 aaagcccgtt catatttacc agtatcttct gcttggaaat agtgatgatt acgaattttt
     2941 tctggcagat agtcttgctt gatccaattt ccaggatagt tgtgtggata gagatagtct
     3001 tgggcattcc ccagttcctt gcttccactg tagtgcccat cacgcaggtg tcgcggaata
     3061 ggcaagtgcc ctgatgtttt gaggtcagca agtgccttat ccatagctac ataggctgag
     3121 ttggattttg gagaaagggc caaatcaatc acgacattgg caatgagaat gcgggcttcg
     3181 gggaaaccaa tcctttgtgc agcatccaga gcagtcacgg tatgaatctg ggcctcagga
     3241 ttggctaagc caatatcttc ataggcgata acagtcaagc gacgagcgag actaggcaga
     3301 tccccagcct caatcaagcg ggcagcatag tggagactgg catccacatc tgagccacgg
     3361 atagactttt gcagggcaga tagaacatca tagtgaccgt ctccatcctt gtccatagtg
     3421 atgtagcttc tctgaagact attttccatg atgtctaagg tgatgtggcg aatgccctcg
     3481 tcattctcag gggtagagag aacagccaag tccagtgagt taaaggcaga gcgaaggtct
     3541 ccgtttgtag aggttgcgat gaaatccagc gcatcctcat ctagttctat tggaaaatca
     3601 aaaccacgtt cagggttact tagagctatc tgcagggcct ctttgacgtc ttggttagac
     3661 agaggttcca actcgaaaat ttgaacacgg ctacgaatgg caggagtgac agagaagaaa
     3721 ggattttcag tcgttgctcc aatcatgatg accagtccac tttccaagag aggcaagagg
     3781 aagtcttgct tggtcttatc tagtcgatga atttcgtcta gcaataggac gagaccacca
     3841 gaaaatttag cttcttccga gatttcttgc agtcgctttt tactatcaac tgtcgcattg
     3901 aaagttcgaa aggcatactt ggtcgttcca gcgatggcag aggcaatact ggttttgccg
     3961 attccaggag ggccatatag aatcatggag gacaggcggt tggcttccac catgcggcgg
     4021 atgatttttc caggtccgac cagatgctcc tgaccgatga cctggtcgat ggttttaggg
     4081 cgcatgcgaa gcgcgagatt gtctggcata gcagtccttt ctaacgtgga tttgagtaga
     4141 atgactcatc tactatatct tactatgtcc attctagcct attagttgtg atatttcaat
     4201 ggttttgtaa taatcaggga gtgagataga atctttttta ctatttaatt taatgaggag
     4261 aggtatcagc atgagagatt tgattttcct taaagctcaa aataggatag ttgagcctaa
     4321 agaagtggaa gtgctgactt gagaaataat attgctgaat gtcattgtat gaactataat
     4381 gaaaagagag gtgataagca atggaaatga tggaccaagt caggaaattt tgatttt
//
LOCUS       DAVBED010000088         4271 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBED010000088 DAVBED010000000
VERSION     DAVBED010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.088"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(89..688)
                     /locus_tag="VQ547_002036"
     CDS             complement(89..688)
                     /locus_tag="VQ547_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543826.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(689..1786)
                     /locus_tag="VQ547_002037"
     CDS             complement(689..1786)
                     /locus_tag="VQ547_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2543827.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(1786..2523)
                     /locus_tag="VQ547_002038"
     CDS             complement(1786..2523)
                     /locus_tag="VQ547_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543828.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(2525..3409)
                     /locus_tag="VQ547_002039"
     CDS             complement(2525..3409)
                     /locus_tag="VQ547_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543829.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(3396..3590)
                     /locus_tag="VQ547_002040"
     CDS             complement(3396..3590)
                     /locus_tag="VQ547_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543830.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(3587..3793)
                     /locus_tag="VQ547_002041"
     CDS             complement(3587..3793)
                     /locus_tag="VQ547_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543831.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         1351 a          947 c          729 g         1244 t
ORIGIN      
        1 gtactattct agtttcaatc tactataggt attgttccat tcactaccgt caattttagc
       61 acatagtctt catgaaaata ttatatcatc ataaccaacc agattctttt gcgatattag
      121 ctgcctctgt tcgattacca gcatccagtt ttgaaagaat attggtgaca tagtttcgaa
      181 tagttccgtt tgagaggtaa agctgatctg cgatttcttg gttggataag ccccgggcga
      241 ttccctttaa gacagcaatc tcttgttctg tcaacggatt gggacgggtc atcaccactt
      301 ccatcaattc aggcgaatac tccttgcgtc cttcgaggac ggtgtgcaag gtttgcatga
      361 ggtctgcaat gcttcgttcc tttaatacat aagcatccac tccagccttg accgcacgtt
      421 caaaataccc agcacgcttg aaggtcgtca ccacaaccac ctttgtttca agcctttctg
      481 atcgtatcca ctccaagact tcaagacctg tcttaacagg catttctacg tcaaggatgg
      541 cgatatctac agactccttt tctaatagtt ggattgcttc ttgcccattc ttggcttgaa
      601 ggacagactc cacatctggt tgaagcgtga gcaattgaca catagcatct cgcaacatac
      661 tttgatcttc tgcgactaat actttcatct actttctctc cttataaggt agtcgaactt
      721 gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat ggaaggacac
      781 gttctcgaac tgtatggagc tcattttctg ttacagtttc aaaacctttc ccgtcatctc
      841 tgaccatcag gagcaattcc tgatctgtgc gttctaattt taagtaggct ttagacgctt
      901 tagcatgttt gatgatgttg gtcactaatt caagcaaaat catggaagcc gttgactcta
      961 attcctgagt taagctagct gtatctagtt gattagctat ttccacctca attccagcaa
     1021 tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac ttaagatttt
     1081 ccacaatggt tcgcacttca cgcattgatt ctttgctaat ctgctgtatt tctcttaatt
     1141 ccttttccac ttgtggataa gcctgtattt gaaataactg caaggctaga tcagttttaa
     1201 cactaagcat agcaaaggta tgccccagac tatcatgcaa atcttgaccg atacgattgc
     1261 gctcattttc tgctagcaat agatttatct gggtattttg cttagtctga gcttctttca
     1321 aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcaaca aaagtaagaa
     1381 ttccaagcag atagactaga aactcaactt cgattctctg aaaaatcaaa agtcgcccca
     1441 caacaaggac ttgagcaaga agaaaagtcc agacatgtaa agactttaaa ctacgtacgc
     1501 tgaaatgata acttaagaga ttggaaagga aaaagaaaaa ccagatataa ttcacagcaa
     1561 caaaggcggt attcccagct acatagatca gcatgatccc ccagaaaagc caagataggc
     1621 gctggctctt agttgttaaa acacccaaat atgccactac aaatagaata tcaatcaata
     1681 aatgccaggc agaaagccac ccagtcacta caggtaggat ggggaaaatc ataaaaatta
     1741 aactggccca aaacatatag tgtatgcttt tcagtctttc aagcattaag cattctcctt
     1801 atgaccttga aggtaaatgg tcaaaccaaa caaaactgct gaaaaaacaa gtagataaac
     1861 tgtggctgat agattgatgc taccctcgtt taagaaggtc ttgagcaact ccatcaactg
     1921 ataagttggt aggcacttcc cgattgcttg catccagtct ggaaataaag agatgggcat
     1981 ccagagtcca cctaaaacag ccaagcctag atagagaaga ttgcccacga cagacatcag
     2041 ctgactagaa ggcaagagtg tcaaggtcaa gccaagcgct acaaaagcta tacttcctac
     2101 tatcagcaag aacgcagccc caatccagct tcctaaagac atatccacac ctctgaccaa
     2161 gtgcccaact gagaaaacaa ccaggattga gaccaaataa tcaaccatca tacttgttat
     2221 ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt tctgccagtt
     2281 gttcatctta tcggtatgta agacagctgg gaatgaaaag atagcggtcg acatcatgga
     2341 aaaggcagtc atggagatga ggtagtcgcg cataaaatta gccggtccac ctggtgtgtc
     2401 ctggtacatg cctgaaaaga atagatagaa ggctgtcggc atccctacag ataataaata
     2461 atagactgat tgccgtttgg tcaatagaaa ttctatcttg tttagtgcaa tccatcgttt
     2521 catcttagtc atctcccttc tgtgtttctt caaagattgt atccaacaaa ctacgattat
     2581 tgacttcgat ttcttgtatc ctacatcctg cttgaactaa cagttcccag aaagcatccg
     2641 cttcgcatgt gactacttgt aaggcatctt gtttttgtac ccagttttca accaagactg
     2701 acttctcaac gacttccttg taagctagcg gaaggataaa atgcttttca atctcctcac
     2761 tacgcatagc tagaggcgtc gtgtcacgaa tcaactctcc cttatttaaa accaaaatcc
     2821 ggtcagctgt atgctctacc tcttcaatat aatgagacga atagagaatg gtgactcctt
     2881 gcgcttttag gtcccgaaca atttcccaaa aacgttgacg agttgaagta tccatggcag
     2941 cagttggctc atctaaaaag acaagctttg gtcgcccaat taaggtcaag ataaaagata
     3001 aaagacgctt ttgcccacct gacaattttt ctgcgaattg ctctttctgt tgctggtcaa
     3061 actgtaatag ttgatcgatt tcctggttgt tcaagggatt tggatagata cgttgaaaga
     3121 aagcaatcaa ctctttaacc tttagttttt gaacaattac attttcttga gggagatagg
     3181 atctcgtata gtctaactta gagctcgtta ccggcaaatc ttggatatat acttgcccac
     3241 tggtgaccaa tttatctcca agcaaacagt ccaagagtgt cgtcttacca gctccatttg
     3301 gcccaatcaa ggcgacgcat tcaccttcag ctacctcaaa ggaaatatcc ttcaaaatag
     3361 ccttactttt gatgttttta tgtaagcctt gtaccttaat catgttcata atattctcct
     3421 ttcaaccact ccattcccat agggaaaacg acggaaatca taaatcctaa tccccaggcg
     3481 ccgcgaataa cttggtgaag aaaggattga tcaaaccaac ctgtaaacat ttctaccaac
     3541 cataccacta gtgatagtcc aataaaaaga aagagaatcg cttttttcat ttttcaagct
     3601 cctttttcac atctcttact aatttcaagc cttctcgtat caaccaagac atgattccaa
     3661 agcttgcaaa caactcccaa ggaaaatgat agaatccttc gtccaatcct gagaacatga
     3721 gataagtcat gactcctgct actactaaac tcactgcgat aatcatttta tttctcatct
     3781 cttcttcctc catttcatac tacaattata gtcttttgaa atcagaggag atagaagctt
     3841 ctgtcactaa aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa gcaagataca
     3901 ctatacaata aaacacaatt agataaatct aaggcaactt cctcaaaaga gatatcaaac
     3961 cccattcaca ctataatgta aactaatact tatttaaagt caaaagagcg gaaattttta
     4021 tcgtacaaac atatatatta taggtaagac aaaaaactct tcaattactt tcttaaaaat
     4081 ttataggagt tataaaatct attaaatttc aatgtggata cctaaactac agtatttatt
     4141 gaaaagactg gagacaaaaa gtatacgctg ccaaaatgaa ttgctgaaaa tcaaaaaaga
     4201 gagaagcaaa ctgattctct cttaatgtat ataatatcta gttataaaaa tacacactca
     4261 catatctctg t
//
LOCUS       DAVBED010000089         4245 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBED010000089 DAVBED010000000
VERSION     DAVBED010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.089"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..1288)
                     /locus_tag="VQ547_002042"
     CDS             complement(<1..1288)
                     /locus_tag="VQ547_002042"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2543832.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VQ547_002043"
     CDS             complement(1366..2613)
                     /locus_tag="VQ547_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2543833.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ547_002044"
                     /pseudo
     CDS             complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ547_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3778..4119
                     /locus_tag="VQ547_002045"
     CDS             3778..4119
                     /locus_tag="VQ547_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2543834.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1351 a          891 c          829 g         1174 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa gcaaccaaac
      421 catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta ttttccacat
     1021 aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag cgtttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgactg atactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct gaacaactag
     2341 ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg gaagaatcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa tcgggagttt
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcggatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc acttttaaag
     4141 atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVBED010000090         4208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBED010000090 DAVBED010000000
VERSION     DAVBED010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.090"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..370)
                     /locus_tag="VQ547_002046"
     CDS             complement(<1..370)
                     /locus_tag="VQ547_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543835.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSG"
     gene            complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQ547_002047"
                     /pseudo
     CDS             complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQ547_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQ547_002048"
     CDS             complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQ547_002048"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2543836.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2422..3018)
                     /locus_tag="VQ547_002049"
     CDS             complement(2422..3018)
                     /locus_tag="VQ547_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2543837.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQ547_002050"
     CDS             complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQ547_002050"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2543838.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1204 a          959 c          756 g         1289 t
ORIGIN      
        1 aaccactccg acgctgatca tggtggtaca gcgtgattgc ttgattctca gctttcccag
       61 acaaaaaagt ccaatagtag gtcagatggc tatcactctc tagaacccga taagaggttt
      121 catccgcatg aagaagaggt tgttctaaca acttttctcg taaaagctta taaagggact
      181 ctaaatagta ttgacttgcc ttgatatgcc aattagagat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattggg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaaactg agccaaagct atgcaccaaa gagaccagca
      361 ccaacaacaa gataattgta catcttaagc tcctttggag ttcattatct gcctctttta
      421 ttagactaga aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg
      481 catcttgcca agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg
      541 agtttagcgg acgttgagct ttggctggaa attgactgga atctactggc ttgacttcga
      601 catctgtatc tttcaaaatt tcaactgcaa aatcatacca tgttgtgtct tctgtcgcat
      661 catttgacaa atgataataa ccaaattcct tacgattttc agctaggtag atcatgaatt
      721 cagccaaggt acgagtccaa gtcggacgac cgtactggtc atttacaact gttaaagtct
      781 tatgagtttt cgcaagattt tgcatggtaa aaacgaagtt tttgccataa tttccaaata
      841 cccaggcagt acggataata tagaaattag acacatgctt ctcaactaac tcttccccca
      901 tacgcttagt gcgtccatat tctgtctgtg gatctggtcg gtcatcaact tcccactctt
      961 gtccaactgg tttcttaccg tcaaagacct agtccgtaga aatataaact agagttgcac
     1021 catgcttttc agatgctttt gcgacatttt ttgtccccat cacattgatg gcgaagtcca
     1081 actcttttcc ttcatcctct gctgcatcaa cagcggtgta ggctgcacaa tggtagacta
     1141 aagtcggttt cacctcttca aaaactttct caaccatttc ttcattggta atgtccatct
     1201 cagccacatc tactgccacg tattcttcat tacgttcatc caataaatag cgaagttccg
     1261 ttcctaattg gccatttgcc cctgtaatta aaatcatctc tagacctttc taatatgtaa
     1321 ctcttcccaa tatagcaata aaaagcagcg atttcctgct ttttatactg taataatctc
     1381 ctgagtctta gcataattgg cttcaacagc ttctttttct gctttccacc attcttggtt
     1441 atctgtatac cacttgattg ttgccttgag cccagcttca aagttggtaa attcaggttt
     1501 ccaccccaac tcatcacgga gcttgctggc atcaatcgca tagcgaaggt catgtcctgc
     1561 acggtcagtc acatgatcat aggcatccgt agcttgtccc atttccttaa ggataagttc
     1621 caaaacttcc ttattgttct tctcaccatc agccccaatc aagtaggttt caccgatttg
     1681 cccttttgtc aagattgtcc aaactcctga agaatggtca ttggtatgaa tccagtcacg
     1741 aacgttctta ccttcaccgt aaagttttgg cttaattcca cttaggatgt tagtaatctg
     1801 acgtgggatg aatttttcga tatgttgata aggaccgtag ttatttgaac agttggaaat
     1861 cgttgccttg actccaaaag aacgcaccca ggctttgaca atcaagtctg atgcggcctt
     1921 ggttgatgag tacggagagc ttgggttgta ttttgtttca gcagtaaatt tctcacctgg
     1981 tccttcacca tgacctggca aatcttctcg taaagggaga tccccataaa cttcatctgt
     2041 cgatacatgg tggaagcgaa tatcatactt acgagcagct tctaaaagag tatagattcc
     2101 aatgaagtta gtatgaataa atggcgatgg atcattgagc gaattatcat tgtggctttc
     2161 cgctgcataa tgaacgatag catctgcttg agcaaccaac ttgtctacca actccgcatc
     2221 agcaatgtca ccaacaacta actcaacacg attgcctaaa atttcctcaa tattcgcgcg
     2281 gtttccagca taagtcaact tatctaggac tgtcacgtga acatctggaa agttctcgta
     2341 aacataatgg acaaagttag aaccgataaa gccagctcca cctgtcacga taatattttt
     2401 gtattcagtc atattctttc cttattccaa atcttctttt ttcaaaggct tcacgtcctt
     2461 aagtagggga tgatgtttgt ctgcttcaga tacgtctgct tcttccagat tttcccattc
     2521 aataccaagg cttggatcag cgtagttcac aaaggcatac ttgggtttga gttcaagagc
     2581 ccagtaatca ttgaccagat agctatatga cactgtatct gataaaactt ggaagccatt
     2641 agctacgcct cgaggaacaa agattccctt gcttgcatca attactgtct gataggtatt
     2701 cccaaaggtt tcaccctcgc gtagatcaac ccaagaaccc agaactttcc ctccatctgc
     2761 tacagagatg tacttatccc aaggctctgc gtggaggcct cgaaggacat ttttacgtga
     2821 gaaggataca ttgttttgca attttccttc tgcaaagaaa gactctggaa atccaagtgg
     2881 aagcactttt tccttttgga aattttcttt aaaccagcca cgattatctc catgaacggg
     2941 gatatcaaac tccaacatgc ctggaatagc ttcaaccttg cgtgccgcaa gcgtcttacc
     3001 gaaaaaatta tctgtcatct atgcttctcc aatcaaacgg agcagatact gtccgtattc
     3061 atttttctta agtggttggg ctaaggccaa tacatcttct cgactgatat agcccatacg
     3121 gtaagcaatt tcttctaagt ttgctacctg aacattttgc atccgttgca ctgtttcgat
     3181 gtactgtgaa gcctctagta aactttcatg agttccagta ttcagccaag caaagccacg
     3241 tcccataagc tcaacagaca aatcaccacg atctaggtaa gccttgttta catctgtaat
     3301 ttccagttca ccacgagggc ttggtttaat actcttggca atttcgacaa catcgttatc
     3361 atagaaatac agtcctgtca ctgcatagtt ggagcgagga tactccggtt tttcttctat
     3421 ggaaatagca ttcatgtctg tatcaaactc aaccacacca aaacgctctg gatccttcac
     3481 ttggtagcca aaaacagtcg cacctttctc tttcttggct gctttttgaa gcattgtgct
     3541 cagaccagga ccatggtaga tattgtcgcc taaaatcaag gcaacgctat cgtcagaaat
     3601 aaactcttcc ccaattgcca aaccatctgt acttggttgc tctgcataag aaagtttgat
     3661 cccaaactca gatccgtctt gaagaagctc ttgaaatcga tgtaaatcct gtggagtgga
     3721 aataatcaaa atatccctaa tcccagccaa catcaatgtt gaaagtgggt agtaaatcat
     3781 cggtttatca taaaccggca taagttgttt tgacgcagcg cgagtcaaag gatataaacg
     3841 tgtccccgaa ccacctgcta gaataatacc tttcatagta gggtaccttt ctttgttatt
     3901 ttagagtcaa ttactattaa ttgtgtactg ctctaaaaag aaaacaatca tcccatgttt
     3961 tatatggctc tataatattt gtagtgggta aatccactat agatattatg gagcctattt
     4021 tattgtagaa aaaaagtccc ataagatcta taatgaaaag cgaccaaaca actcattaga
     4081 aagattcata tgggacaatt acattttatc acaaaactac tcgatatcaa agacccaaac
     4141 atcaagattc tagatatcat caatatggat acccacaaag aaattatcgc taagctggat
     4201 tatgaggc
//
LOCUS       DAVBED010000091         4116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBED010000091 DAVBED010000000
VERSION     DAVBED010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.091"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQ547_002051"
     CDS             <1..776
                     /locus_tag="VQ547_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543839.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQ547_002052"
     CDS             805..1713
                     /locus_tag="VQ547_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543840.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQ547_002053"
     CDS             1715..3613
                     /locus_tag="VQ547_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2543841.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQ547_002054"
     CDS             3637..>4116
                     /locus_tag="VQ547_002054"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2543842.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBED010000092         3297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBED010000092 DAVBED010000000
VERSION     DAVBED010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.092"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(384..1859)
                     /locus_tag="VQ547_002055"
     CDS             complement(384..1859)
                     /locus_tag="VQ547_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2543843.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2566..3297
                     /locus_tag="VQ547_002056"
                     /pseudo
     CDS             2566..3297
                     /locus_tag="VQ547_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1041 a          704 c          612 g          940 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
      361 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
      421 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
      481 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
      541 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
      601 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
      661 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
      721 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
      781 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
      841 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
      901 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
      961 ttgatttcat gacgagcgta ctcggatagc tcaatgactt cctcaaacga ctctttacca
     1021 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta agaggcagat
     1081 gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg ctccccgatt
     1141 aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac tgctgccata
     1201 tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa atgcgctcca
     1261 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
     1321 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
     1381 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
     1441 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
     1501 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
     1561 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
     1621 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
     1681 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
     1741 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
     1801 ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
     1861 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
     1921 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
     1981 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
     2041 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
     2101 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
     2161 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
     2221 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
     2281 gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa tagtacacct
     2341 ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg ttctgttctt
     2401 gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc cacccagccc
     2461 tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga aaacacctct
     2521 gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagaaatgca agacaattat
     2581 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     2641 gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca aactatccac
     2701 actaaaatca agcgtaggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     2761 tattctgccg actatgctca acagtcttat gaaaataatc gcaagcactc ggtcaagaga
     2821 tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca aaaatttttg
     2881 cctgaaatga tggttatggc taaaggggtt aacgtgggaa tttcaaccat ttactattgg
     2941 attcatcatg gaaaattggg gtaaagcaag caggatctgc tttaccctag aaaaggaaaa
     3001 gtgcttaaga aacaggccag caccaacttt aaacctgctg gtcaatccat cgaacagcgg
     3061 cttgaagcta tcaattttcg cttggagaat gggcattatg agattgatac ggttctactt
     3121 acgagagcga aaaactactg cttgcttgtc ttgacggatc gaaaaagtag acatcagatc
     3181 atccgattga ttccaaataa aagtgctgag gtggtcaatc aggctctaaa actcatctta
     3241 aaacaacaca agattctttc catcacggca gataatggaa cggaattcaa tcgcttg
//
LOCUS       DAVBED010000093         3275 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBED010000093 DAVBED010000000
VERSION     DAVBED010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.093"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(229..840)
                     /gene="rpsD"
                     /locus_tag="VQ547_002057"
     CDS             complement(229..840)
                     /gene="rpsD"
                     /locus_tag="VQ547_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2543844.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1035..2087)
                     /locus_tag="VQ547_002058"
     CDS             complement(1035..2087)
                     /locus_tag="VQ547_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2543845.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2084..2782)
                     /locus_tag="VQ547_002059"
     CDS             complement(2084..2782)
                     /locus_tag="VQ547_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543846.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2949..>3275)
                     /locus_tag="VQ547_002060"
     CDS             complement(2949..>3275)
                     /locus_tag="VQ547_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2543847.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
BASE COUNT          920 a          735 c          629 g          991 t
ORIGIN      
        1 aataagagag aattttttta cgaaaatcta ttgaatatgc cataaaagga ttataccaca
       61 ttgtgtacta tttttggttc attttactat atcactttgg actatatcgg tctagttatg
      121 tctaaacgat tatagctgga tactaagaga aatcaaaaaa gcactaaggg agaacgtccc
      181 aaagtgctta atatcaaggc ctcaaagcct gtcttattca ataaaatatt acaacatctt
      241 gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg ttgatttcgt cgcgttctgg
      301 caagcgagtc aatgaacctt ccaatttttc agcgtcgaat gatacgaatg ctggacgtcc
      361 aagagtagct tctactgctt caaggattgc tggaactttc aatgattttt cacgaactga
      421 gatcacttga cctggagtta cgcggtatga tgggatatca acgcgtttcc cgtcaacaag
      481 gatgtgaccg tggtttacga attgacgagc ttgacgacga gtagtcgcga gaccaagacg
      541 gtaaacaacg ttatccaaac gacgttccaa aagaagcata aagttgaaac ctaggattcc
      601 gcctttgatt tttgtagctt gtacgaacaa gttacggaat tgtttttcac ctacaccgta
      661 agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg tattctgaca atttagaacg
      721 gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt gccaattctt tacctgtacc
      781 tgtaagtgaa aggccaaggc gacgagcttg tttccaagat ggtcctgtat aacgtgacat
      841 atgaatgtcc tcctgatata aataatattt cggtggaaat agtcacttag aaagccctga
      901 ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt gtcataagac acctgttgac
      961 gagcttcatg ctttcctgct gatatttcac acaaaatcca ttttaccatg aatagctgga
     1021 tttgtaaagg ggttttaggc tttattttca ctaccagaga gattgagaac gagggtaaag
     1081 gtacttccta gaccgtactg gctgctgact gtgatttccc cacccaattg atgggccaat
     1141 tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct tcatgttacg cgaagtttcg
     1201 acacgataaa ggcgtttgaa aatattttcc aaatcctctg gggcaatgcc ctgcccttca
     1261 tcggtcacac tgattgaaag ctggcccttc tccagcttag tcaccacttc cagcttggtt
     1321 cctggagcag aatatttaaa agcgttatcg accagattca ccaagatacg agaaagctta
     1381 gcataatctc cctcaatccg ggcagactct gggattacct gcaagtggac atctcttctc
     1441 tcctgctcaa tcaaaaactg aaattcactc atgcactcaa ttaagagctt gtccagaaaa
     1501 atactgtctt tactggtagt ttccacctga tttctagctg tgtttagggt caaaaaattc
     1561 aactcctcaa ccagtttatt gagcctctcc gtctggcgtc caatggttgc tagataatga
     1621 gcttgctccg actccttgat aatcccatcc aaaatccctt ctaccgtcgc ttggatcgaa
     1681 gtgatagggg tcttaatatc atgcgacaac tgggcaatca tcaagccctt ttctcgttcg
     1741 ctttcttcca aggaatcaaa gcttacctgc aaatcatggg acatctcatt aaaagtttgc
     1801 cctaattgct gaaattctac aggaccttga acctccaaat ttgaaggaaa atccttggcc
     1861 gctacccgct tggcatgctc cttgagtttg cccaacgacg taaagactgg caataggaga
     1921 aagagactaa tcccagcacc gacaaggctg gcaacgatgg tcatcccaag caaaaagtaa
     1981 atctcgcctt tcgcaatcag cattttttga acagcccaaa aaacaaccaa aatggttaag
     2041 agggttgaaa taatatatcc aaccaaaata taacttttta gtttcatgtt tgtcctctcg
     2101 gtttctctat cttatatccc aacccccaaa ctgtcttaat agtgggcgtt tggtcactac
     2161 tatattttgc cagctcctgt cgaagagcat ggatatgcac attcaaggta ttggtgtcat
     2221 ccacgtagtc ttctttccag atcttttcat agaggtctgt cttggagaaa actcgctctg
     2281 gattgctagc taaaatccac agcaattcaa atgatttaac agttaaatcc agcatttctt
     2341 ctcctatttg aacttcatga ctactatgat tcatttttag attgccaagg gaaatcagct
     2401 ctgtttcgcc cccacgatga aggcggcgca aaatattgtg gacacgcaaa accagctcac
     2461 gtgggctaaa aggcttagca ataaaatcat ctgctcccaa gctcaggccg taaatcttgt
     2521 cctgttcact ggtcttagca gtaataaata ggaaaggctg ctctggtgat aagtattgaa
     2581 cctcactgat taaatcataa ccatccatcc gaggcatcat aacatctgtg ataatcaaat
     2641 caatcggttt tttcttgaac agctctagcg cttccagtcc atcatgggct accaagacct
     2701 gataacctgc ctgaattaag tatctctgat gaatatctgt gatttctacc tcgtcgtcaa
     2761 cgagtaaaat tgtctttccc atctgtctct cctttgataa aaacagtgct atactgcttt
     2821 aagtataaca ctatttttat tgttttacga tgattttaat ctgctattga aagaaagtcc
     2881 tgattgctga ttgagttgtt aaactaatct tagtcagccc actatccatc atttatttcc
     2941 ttagctgatt agttttcttc ttttttgttt ttcaaaccta gaccaccgag taaacctgca
     3001 agcgcaagcc caaggaaacc aatacttgcc attgatgttt gagtctcacc agtatttggt
     3061 agcatagctt tatcctctga catcatcgta tcagacatct tgttagcaga agcagccatg
     3121 ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt cagcaggcat gctatctgta
     3181 gtacctgtag catgattgtg attcatcgga gtcacgccag aaccagagtt agaaggtgat
     3241 aatgaaccat ttgctgtgtc tgatgtttct ttaac
//
LOCUS       DAVBED010000094         2841 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBED010000094 DAVBED010000000
VERSION     DAVBED010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.094"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQ547_002061"
     CDS             complement(481..1206)
                     /locus_tag="VQ547_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543848.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQ547_002062"
     CDS             complement(1219..1956)
                     /locus_tag="VQ547_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543849.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQ547_002063"
     CDS             complement(1949..2677)
                     /locus_tag="VQ547_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2543850.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2830)
                     /locus_tag="VQ547_002064"
     CDS             complement(2711..2830)
                     /locus_tag="VQ547_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate dehydrogenase"
                     /protein_id="HET2543851.1"
                     /translation="MIGIVFAIFLDFPVEYGISLGLLNGIVLGSLIVYKNNKN"
BASE COUNT         1083 a          433 c          338 g          987 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt g
//
LOCUS       DAVBED010000095         2608 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBED010000095 DAVBED010000000
VERSION     DAVBED010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.095"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            190..504
                     /locus_tag="VQ547_002065"
     CDS             190..504
                     /locus_tag="VQ547_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543852.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            514..720
                     /locus_tag="VQ547_002066"
     CDS             514..720
                     /locus_tag="VQ547_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2543853.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            720..917
                     /locus_tag="VQ547_002067"
     CDS             720..917
                     /locus_tag="VQ547_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543854.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            973..1653
                     /locus_tag="VQ547_002068"
     CDS             973..1653
                     /locus_tag="VQ547_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2543855.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1665..2306
                     /locus_tag="VQ547_002069"
     CDS             1665..2306
                     /locus_tag="VQ547_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543856.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2324..2554
                     /locus_tag="VQ547_002070"
     CDS             2324..2554
                     /locus_tag="VQ547_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543857.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          761 a          427 c          537 g          883 t
ORIGIN      
        1 gaagctgacg tggtttgaag agattttaga agagtattaa tgatagataa agtggtcagg
       61 aacctactcc tgaccttttt cttttgcaaa atgacaaaaa tcataatttt tttgacaact
      121 atacttgtca aaaagaaaaa gatgtgttac aatgtaagca agttaagaga aaagaagaaa
      181 ggagctatga tgtgggtact agggtttata ctatttctga ttttctttta ttctaatgat
      241 tctaaaaaaa tcaagaaact agagaagaaa atcaaaagac ttgagcgaaa agagaaagga
      301 aatgcagaaa tgtcgagatt attacaagaa atgattggaa aggaaccaat tataacggga
      361 gtgtatattg ggccagataa ctgggaagtt gtggatgttg atgaggaatg ggtaaagcta
      421 cgacgtgtag ataatacggg aaaagaaaaa ttcaagttgc aacgtattga ggatatccaa
      481 accgttgaat ttgacggaga gtaggtgtgt aacatgcaac taaaaaatcg tctaaaagag
      541 cttcgagctc gcgatggtct caatcaaacc gacctagcca aactggcagg ggtttccaga
      601 cagaccatta gcctactaga acgggatgag tacaccccat ccattatcat tgccctgaaa
      661 atatctcaaa ttttcaacga aacagtcgaa tcggtatttc gtttggagga ggacgagtga
      721 tgaacaagta taaagtgatt tattatgtag tggtcatagc tttattagtc agcgtatttc
      781 tactgattgg gatggaccta agctggttta atccctatca aagcgaccaa tttgtttggg
      841 tctactttgc tctcatccca gtaattgaat ggattgaaaa gaaatccaaa aatctagcaa
      901 gtgaaaaagg agaatgaata tgaaaaagaa acgtagattg ttatttttga tgtctattgt
      961 cttggggggt tcttgggcat gtttgtaggg atgtttaagg cacgtgtcga atcccacgaa
     1021 attattttag atgtaaaagc cttgatgcca tggatatcag ctatttgttt actgataggt
     1081 ttcattagta tgtttttgac tttcaatttc ttaaagaaaa gcagaaaatt tcattccttg
     1141 tatcaagagg aaatggatga cgatctgaat gaaacctatt atgtgcaaat gtatcggaat
     1201 cttgagtttg gaaccattgc ttttaatatt acaggtgtag tgattccatt ggctattttt
     1261 atttcattaa gtgaggtgat tatattgcat acaaaccctc aaacattttt cctttctttc
     1321 ttactctttg tggtattctt agtcgctcaa aaatctcttt ttaaaaccat tgcgattgtt
     1381 cgtcagtttg atttggaatt tttcgctaca ccaaaggatg tcttgaacta tataaattct
     1441 tatgatgaag gggagcgtca ggctaatttg gaacagagtt ttcgaatttt attccaatta
     1501 caccaatatg tcttaccagc cttatatatt tttcttatta tcctttcttt cttgacagga
     1561 gagattcagt tactagcttt cttgcttgta ggagccatcc atgtttatat caatgtgatg
     1621 cagttaccta tggtaaaacg ttatttcaaa taaaggagtt atctatgaaa ttacttaaaa
     1681 accttggctg gtttcttcta gcccttctat cctttttctt tatctatggc tttattcagg
     1741 ggctcgcgac tgcgtcgctt gctttaggcg cttcacccta tgctgttact ctactctatg
     1801 tggtcttggc tggagtatat gtgtacggca tttacaaatg gtatcagaaa gctcctgttt
     1861 atattgagaa gagcggcttt aaccgattta tttggcttcc tgccttggtt tggttcttat
     1921 ctctggtcgt tcaattcttc ttgccagatg atccttcagt aaatcagcaa atagcgacag
     1981 acttgacctt gtctcaacca cttttctcat tctttgctgt ggttattttt gctcctttga
     2041 cggaagagat tgtttttaga gggatgttag cacgctatct ctttcctaag caggacaata
     2101 gtaaacgaac cctgattttt cttctggtat ctagtcttct atttgccttg attcattttc
     2161 caggtgatgt gcaacaattt tttgtctatt ttagccttgg ttttagtttg ggtttggctt
     2221 acattagcag aaaaggtctg gtctacagta tttctcttca cgctttgaat aatttagtcg
     2281 gctttttgat gattctcatg ctataataga gtcaggaggt cacatgaaac gagtaatttt
     2341 attagcagtg attcaggcag tcgttctatt tttcatcatt ggagcgctag cttatgcctt
     2401 caaaggcgat ttcttctata actatctagc agttgtcttt gctcctattg caggtgtact
     2461 gcgttttggg acggcttaca taacggaaat tgtcttgcct cgaaaggcag ccgaaatcgc
     2521 tgaaaagcgt aaagcaggca aaaattcaaa ataaaagagt ccggtgaagt tcatcggatt
     2581 tttgtattat actcaatgaa aatcaaag
//
LOCUS       DAVBED010000096         2328 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBED010000096 DAVBED010000000
VERSION     DAVBED010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.096"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(1..404)
                     /locus_tag="VQ547_002071"
                     /pseudo
     CDS             complement(1..404)
                     /locus_tag="VQ547_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(349..531)
                     /locus_tag="VQ547_002072"
     CDS             complement(349..531)
                     /locus_tag="VQ547_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2543858.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            888..>2328
                     /gene="pcpA"
                     /locus_tag="VQ547_002073"
     CDS             888..>2328
                     /gene="pcpA"
                     /locus_tag="VQ547_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2543859.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT          818 a          348 c          379 g          783 t
ORIGIN      
        1 tttttacttc cgtcacatca atcattaccg tgtcctcaga actgagagga gttcttgaaa
       61 tcgtaacacc acctttgaac aagagttact tcaacccatt agctccgacg gattaagttg
      121 ctttcgtgaa taccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat
      181 tgaagagtgg ccataagaag gtcttctagg cttaatttag gttttcgtcc accttttgtg
      241 tgtttaagtt gataagctgt ttttaacaca gctaacatct cttcaaaagt ggtgcgctga
      301 acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt tacttgcttc ataatttcgc
      361 agggagtcta ttgactcttt ggtaggtgtc aatgtttttt tcatctatcc cgagaattat
      421 tttcccgcca tttgtatttg caaatgctga gtaggtttcc cagaaagact ctggaagatt
      481 gtttttagct tttttgtatt ctaaatcaac cccttcaaat tttaagtcca tatttttcct
      541 ttacatctgt tttttgtggt tctggtattt gttcaagttg agtgataata tagcgaattg
      601 aatttcgaga gtttttactc agttaatttc ttttttaacc cactttaatt tcttttttaa
      661 cccactttaa tttctttttt aacacgggtt aaaaaagaaa ttaaagtggg ttaatttttc
      721 ttgacttaaa atttaaaaat gatatactgt gtttatggag agatgacaat ttataaaatg
      781 tactactcta ttctactaga taatgattga ataaaacttt ttataacaac ggctagcaaa
      841 gttataattt tatatctatt agaaaataaa tatgtaagga aatttaaatg aaaaaaacta
      901 caatattatc attaactaca gctgcggtta ttttagcagc atatgtccct aatgaaccaa
      961 tcctagcaga tactcctagt tcggaagtaa tcaaagagac taaagttgga agtattattc
     1021 aacaaaataa tatcaaatat aaggttctaa ctgtagaagg taacatagga actgttcaag
     1081 tgggtaatgg agttactcct gtagagtttg aagctggtca agatggaaaa ccattcacga
     1141 ttcctacaaa aatcacagta ggtgataaag tatttaccgt tactgaagta gctagtcaag
     1201 cttttagtta ttatccagat gaaacaggta gaattgtcta ctatcctagc tctattacta
     1261 tcccatcaag cataaaaaaa atacaaaaaa aaggcttcca tggaagtaaa gctaaaacta
     1321 ttatttttga caaaggcagt cagctggaga aaattgaaga tggagctttt gatttttctg
     1381 aattagaaga gattgaattg cctgcatctc tagaatatat tggaacaagt gcattttctt
     1441 ttagtcaaaa attgaaaaag ctaacctttt cctcaagttc aaaattagaa ttaatatcac
     1501 atgaggcttt tgctaattta tcaaatttag agaaactaac attaccaaaa tcggttaaaa
     1561 cattaggaag taatctattt agactcacta ctagcttaaa acatgttgat gttgaagaag
     1621 gaaatgaatc gtttgcctca gttgatggtg ttttgttttc aaaagataaa acccaattaa
     1681 tttattatcc aagtcaaaaa aatgacgaaa gttataaaac gcctaaggag acaaaagaac
     1741 ttgcatcata ttcgtttaat aaaaattctt acttgaaaaa actcgaattg aatgaaggtt
     1801 tagaaaaaat cggtactttt gcatttgcag atgcgattaa acttgaagaa attagcttac
     1861 caaatagttt agaaactatt gaacgtttag ccttttacgg taatttagaa ttaaaagaac
     1921 ttatattacc agataatgtt aaaaattttg gtaaacacgt tatgaacggt ttaccaaaat
     1981 taaaaagttt aacaattggt aataatatca actcattgcc gtccttcttc ctaagtggcg
     2041 tcttagattc attaaaggaa attcatatta agaataaaag tacagagttt tctgtgaaaa
     2101 aagatacatt tgcaattcct gaaactgtta agttctatgt aacatcagaa catataaaag
     2161 atgttcttaa atcaaattta tctactagta atgatatcat tgttgaaaaa gtagataata
     2221 taaaacaaga aactgatgta gctaaaccta aaaagaattc taatcaggga gtagttggtt
     2281 gggttaaaga caaaggttta tggtattact taaatgaatc aggttcaa
//
LOCUS       DAVBED010000097         2118 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBED010000097 DAVBED010000000
VERSION     DAVBED010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.097"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            368..1714
                     /gene="gdhA"
                     /locus_tag="VQ547_002074"
     CDS             368..1714
                     /gene="gdhA"
                     /locus_tag="VQ547_002074"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2543860.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          673 a          384 c          401 g          660 t
ORIGIN      
        1 ttggatttct tctttagttg atttcatatc actattatat aatgattttt gattttagtc
       61 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
      121 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      181 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      241 tattttcaaa aaaaccaaaa actgaattga aagaattttt agaaaatttc tgttttttct
      301 ttacagtgaa aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga
      361 gaacgatatg acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg
      421 taacgggcac gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttagaacc
      481 tgtatttgaa aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc
      541 tgagcgcgtg gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa
      601 ccgtggttac cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt
      661 ccacccaact gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa
      721 tgtcttgact ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg
      781 taaaacagat gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca
      841 catcggacca tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg
      901 ttacctttac ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa
      961 acctcttgga tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta
     1021 ctatactgaa gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat
     1081 ttcaggttct ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac
     1141 tgttatttct gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga
     1201 tcttttggtt gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa
     1261 agcaactgca acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc
     1321 tcttccatgt gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca
     1381 aggcgttatc tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt
     1441 ttacaaagaa aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc
     1501 cgtttcagct cttgaaatga gccaaaacag tcttcgcctc tcatggactc gtgaagaagt
     1561 tgatggccgt ctcaaagaca tcatgacaaa catcttcaac acagctaaaa cgacttcaga
     1621 aacatacggt cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt
     1681 agcaaatgcc atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac
     1741 tacgattggg gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa
     1801 atgaaataaa aactgaacaa attgattgcg gaattcaaac caatttctaa catacttcta
     1861 gaaattaatt tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta
     1921 cttaaccctt tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct
     1981 gtacttgagt acggcaaggc aaagctgacg tggtttgaag agattttcaa agagtattaa
     2041 acaaaaagaa aaaccgctac tcctaagaat agcgatttaa tcatgttttt aagctactac
     2101 tgtagttgct ctattatt
//
LOCUS       DAVBED010000098         2034 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBED010000098 DAVBED010000000
VERSION     DAVBED010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2034
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.098"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..398)
                     /locus_tag="VQ547_002075"
     CDS             complement(<1..398)
                     /locus_tag="VQ547_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543861.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLIS"
     gene            complement(713..1771)
                     /locus_tag="VQ547_002076"
     CDS             complement(713..1771)
                     /locus_tag="VQ547_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543862.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
BASE COUNT          757 a          349 c          267 g          661 t
ORIGIN      
        1 tatgaaatta gtgttgtaaa gtacaagaag tagtaaaatt taaacagatt cttagttgtt
       61 tgactctcct tataaaacac tgctattcct ggactaaatc ccattagttg gtgaaagaga
      121 attcgatagt atttcctagc tcctataatg atcacaaata taaaataaaa ataaattggt
      181 cttaatttac aaaagattga ggaaactagt aatagcaaag tatgtaagca ttgagacaaa
      241 atatagaata acggtatcgc caatacaaag gttaagatgg catgagaggg ggttcctaag
      301 atgtccaatt ttataaatac tgggctgaca caaaatatcg tgcttataag cagtaaaatc
      361 attaaaattg tgtcaaaaaa ataacgctta tttttcattt agtctacttt ccattgttaa
      421 ataatactac tgctaacacc aagccaactt agcacattgc atcacctaat cctgcgctac
      481 ttgtccataa tcctttaatg tttctactaa aattattcca atttccccca tcaagatagc
      541 ttatttatcc tagacaatgc ctactgcaac agtataaata agattcatca gccatctttt
      601 ctggcaatca tatgggtagc ctaatgatat ttctagttac tcaaaaatat ctagctatac
      661 tagagttatt tctaatccct aggacacttg ttaatccaaa tgtaacaaat tttcacccct
      721 taataggact ctttctggaa aaaatataag gtctatcttt ataaaaaaat ctatcatatt
      781 gggatggcat gcatctggaa tttaaacaag ctataaattc atttataact actatttgtt
      841 tagaggcaac agcatcttgt ataccgccat cgaaagaacc atcttgtaat tccgaaatat
      901 ttctgtttaa atattgtttt gacaaatctc ctaatgcttc attatcgtaa atgattccca
      961 aaaatccaac cttatatagt aaataattta aacttacaaa gtaattgaat cccatagtat
     1021 atttttcttt ataaagcaaa ggtaaaactt tataaaaaat atctaagtca acctcactct
     1081 gattctgaag caagtaggag tcaagcaaat tttcaaaaat agctaacaat atgattggtg
     1141 taaggttttt gtattcacat gtcaagtatt ccgagtatcg tgcagatgat atttctttta
     1201 tataactttt tgaaagcaag attttttcaa attcatcatc tattattaat cttctatttc
     1261 caatccaaac ggtattacca cccaaataag attgtgcaaa tagcaatatg taagaaaata
     1321 tgaacgtaaa tactgaaaga ggtagaattc tatgcgtaaa aaaatagacg ataatggtag
     1381 ccaggagtaa agctatctct cgtgacaatc gaattctttt cagcatcttt tttaacagtc
     1441 cgtaaggttg tccttggcaa tattcttgaa ctaaattaat cggaatgaca tctctcacca
     1501 tttctggaaa gtagagtaag tttataggtt gaaatctcca gctcccatca taagtaaatg
     1561 gatatagaac caaatactta aaagattttt ttcttataaa cttaattatc acaatatgaa
     1621 tgactgttgc aatgaagtat attaaatata aaagtaaaac cgccatcaat atacttacaa
     1681 aaatcccctt ggactcaatc aatggaaaat aaaatattgc aactagaagc gaataaagtc
     1741 ccgctaataa atatttctga tcatctttca ttcaaaacac catattattt actaagaata
     1801 catcaataca atagagcaac tctgtaagtc aatatttgat aaagcaaagc tttaaaccct
     1861 tccccagacg ttagcttttc ttcaatccac tacagttgac aaggagccca aattattgat
     1921 aaaaacttta gtcatcatcg tctctataaa aatattttct atacactctt gataatacca
     1981 aaattaatgc caatatcata ccaagagcta taataataga atttattaga ttta
//
LOCUS       DAVBED010000099         1879 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBED010000099 DAVBED010000000
VERSION     DAVBED010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.099"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..260
                     /locus_tag="VQ547_002077"
     CDS             <1..260
                     /locus_tag="VQ547_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET2543863.1"
                     /translation="QIKSALEEELSNRGYDVHCDAVMVKDVNEDLMKGYDIFTPIAAT
                     DLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            308..1783
                     /locus_tag="VQ547_002078"
     CDS             308..1783
                     /locus_tag="VQ547_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2543864.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          539 a          379 c          378 g          583 t
ORIGIN      
        1 accaaattaa aagtgctcta gaagaagaac tttcaaaccg tggttatgat gttcactgtg
       61 atgcagtcat ggtgaaagat gtaaacgaag accttatgaa aggttacgat atctttacac
      121 caatcgctgc aacagacctt ggttttgaac caggtatccc agttatcgaa gctgggccaa
      181 tcttattccg tatcccagca atgagcgctc cagtatttga caatattgaa gcagctatta
      241 aagaacacgg attaagctaa ttctaatttg ttaacattca tataacataa aaaagggagg
      301 aactgttatg gatgcaatct ttgacctaat cggaaaggtt ttcaatccca ttttagaaat
      361 gggtggacct gtcatcatgt taatcatttt gacagtattg gctttacttt ttggagtgaa
      421 attctccaaa gcgcttgaag gtggtatcaa acttgccatc gctcttacag gtatcggtgc
      481 tatcatcggt atgctaaatg gtgctttctc agcatcactt gcaaaattcg ttgaaaacac
      541 tggtatccaa ttgagtatta ccgacgttgg ttgggcacca ctcgcaacaa tcacttgggg
      601 ttctgcttgg acactatact tcttgctcat catgttgatt gtcaacatag tgatgctagc
      661 tatgaagaaa acagatacac ttgacgttga tatctttgat atctggcact tgtctatcac
      721 aggtctcttg attaaatggt atgctgataa caatggtgtg agtcaagggg tttcactctt
      781 tattgctaca gcagctatcg tccttgtcgg tgtgttgaaa attatcaact ctgacttgat
      841 gaaacctaca tttgatgacc ttcttaacgc cccaagttca tcaccaatga catcaactca
      901 catgaactac atgatgaacc cagttatcat ggttttggat aagatttttg aaaaattctt
      961 cccaggcctt gataaatatg actttgatgc tgctaaattg aacaagaaaa tcggtttctg
     1021 gggatctaaa ttcttcatcg gtttcatcct tggtatcgtt atcggtatta tgggaactcc
     1081 acatccaatt gcaggtgttg cagatgcaga taaatggcgt cttgttatca aaggatggtt
     1141 gtctcttggt ttgactgccg gtgtatcttt ggaactcttc tcacttatcg gttcatggtt
     1201 catcgcagcc gtagaaccac tatcacaagg tattacaaac gttgctacta aacgtcttca
     1261 aggacgtaaa ttcaatatcg gtcttgactg gccattcatc gctggtcgtg ctgaaatctg
     1321 ggcttgtgcc aacgtacttg caccaatcat gttgattgaa gcagtgcttc tttcaaaagt
     1381 tggaaatggt atcttgccac ttgcaggtat catcgctatg ggtgttactc cagctctctt
     1441 ggttgtaact cgtggtaaat tgctccgtat gattatcttc ggaacactct tgttgccact
     1501 cttccttctt tcaggtacac ttattgcacc atttgcaaca gaacttgcta aaggtgtagg
     1561 tgccttccca gaaggtgtga gccaaactca attgattact cactctactc ttgaaggacc
     1621 aatcgaaaaa cttcttggtt ggacaattgg taacactaca actggtgata tcaaagcaat
     1681 ccttggtgca gtagtcttcc ttgtattcta tatcggtatc tttgcttggt acagaaaaca
     1741 aatgatcaaa cgtaacgaag agtacgcagc aaaagcaaaa taatgcgctc ctataaaata
     1801 taaactcaat gaaaatcaaa gagcaaacta ggaaactagc cacaggttgc tcaaaacaca
     1861 gttttgaggt tgtagataa
//
LOCUS       DAVBED010000100         1638 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBED010000100 DAVBED010000000
VERSION     DAVBED010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.100"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQ547_002079"
     CDS             108..407
                     /locus_tag="VQ547_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2543865.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQ547_002080"
     CDS             409..1179
                     /locus_tag="VQ547_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2543866.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQ547_002081"
     CDS             1199..1363
                     /locus_tag="VQ547_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543867.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          601 a          180 c          267 g          590 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaact
//
LOCUS       DAVBED010000101         1529 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBED010000101 DAVBED010000000
VERSION     DAVBED010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.101"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ547_002082"
     CDS             84..491
                     /locus_tag="VQ547_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2543868.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQ547_002083"
     CDS             656..955
                     /locus_tag="VQ547_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2543869.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..>1529
                     /gene="tnpB"
                     /locus_tag="VQ547_002084"
     CDS             1216..>1529
                     /gene="tnpB"
                     /locus_tag="VQ547_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2543870.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITP"
BASE COUNT          522 a          304 c          275 g          428 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactcc
//
LOCUS       DAVBED010000102         1389 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBED010000102 DAVBED010000000
VERSION     DAVBED010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.102"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(704..1389)
                     /locus_tag="VQ547_002085"
                     /pseudo
     CDS             complement(704..1389)
                     /locus_tag="VQ547_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          386 a          283 c          287 g          433 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaat
//
LOCUS       DAVBED010000103         1251 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBED010000103 DAVBED010000000
VERSION     DAVBED010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.103"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(1..368)
                     /locus_tag="VQ547_002086"
                     /pseudo
     CDS             complement(1..368)
                     /locus_tag="VQ547_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(817..1215)
                     /locus_tag="VQ547_002087"
     CDS             complement(817..1215)
                     /locus_tag="VQ547_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543871.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          352 a          249 c          205 g          445 t
ORIGIN      
        1 agcgcttttc cttttctagg gtaaggcaaa tcctgcttgc ttaaccccaa ttttccatga
       61 tgaatccaat agtaaatggt tgaaattccc acgttaaccc ctttagccat aaccatcatt
      121 tcaggcgaaa atttttggtt atgatagtgg agaatctttt cctttagttc cttggtcaag
      181 cttgatttct tgaccgagcg cttgcgattg ttttcataag actgttgagc atagtcggca
      241 gaataaacct ctttgaagcg cccttttcca agacattgtc ggactgtcct acgcttgatt
      301 tcagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct atttgatttc
      361 cctttgttcg ccttttgtag tataatggtt ttgcatctct gtgcctttct tgtgtttgtg
      421 gttgaacaac aagtataaca caaaggtgtt ttcttatgcc tacaagagct ttcattattt
      481 ccattttctt ttggatttca ctctattctg aaaaacttgt gtatatttac tgaagctagc
      541 aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa tctcggatta
      601 atgtcaattt aaaaagatag agagttttta gtttaaataa attgttttaa aatatcaaca
      661 acatcacttc ttttcttaac ctgataagcc ttgattccta attttggggc tacgattata
      721 ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta tttatcgata
      781 gttactcata tatatcagtc cacctccata ctcaccttac agattctttt gataataata
      841 tctttgccta atgtagagat agtcttgcaa agaaaaaact tccttgtagc catgtttctg
      901 ataaaagtcc ggtgcctgga actggtaagt attgacaaag gcaaaacaac aatttcgatt
      961 cttagcttca ctttctgcct gttgcaatag ttttgaaccg attccttgcc ctcgcagttc
     1021 ctcttttaca aacaaatact cgatttctag ccaatttcca aaagtctctg ctatcaaacc
     1081 cgcaaggaga ttgccctttt catcttcgac ataaagatta agtggctcac tttcagcctc
     1141 ttctcttttt gaacggttat aaacacgaat cagattccct atttcttgcg atttatgtga
     1201 ttccttattt tccaatctaa agtataatga aatgaaataa aacatgcgca a
//
LOCUS       DAVBED010000104         1056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBED010000104 DAVBED010000000
VERSION     DAVBED010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.104"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            105..>1056
                     /locus_tag="VQ547_002088"
     CDS             105..>1056
                     /locus_tag="VQ547_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2543872.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          373 a          189 c          220 g          274 t
ORIGIN      
        1 aggttcaagg gttcctgttg tcaaatgaaa tgtgatttaa ggtataagaa aacacctctg
       61 tgctatactt gttgttcacc acaaacacaa ggaaaggcac agagatgcaa gaacattata
      121 ccccaaaagg gaaacatttg acaatagata accgtcgctt gattgagcgg tggaagaatg
      181 aaaataagtc caatcgtgaa attgcaggct tgttaggaaa ggcgcctcaa acgattcata
      241 atgaagtcaa aagaggtaca actttacaac aagtgagaaa agggctatac aaaaaggtct
      301 attctgccga ttacgcacaa actgtttacc aattcaatcg aaaacggtcg gtgaaaaagt
      361 taattttaac aaaggaaatc agagagaaga tcttacacta tcataagcaa aaattttcgc
      421 ctgaaatgat ggttaacaag aagcaagtga aagttggtat ttcaaccatc tactactggt
      481 ttcataatgg tcatttagga ttgacgaagg ccgacatgct ttatcccaga aaaaggaaag
      541 gtgtcaagaa gcaagctagt ccgaacttta agccggcagg taaatctatc gaagaacgtc
      601 ctgacgttat taatcttcgc ttggaaaatg gtcattatga aattgatacc gtcctactga
      661 ctaagataaa aaattattgc ctgttagtct taaccgaccg gcggagcaga caccaaatta
      721 taaggttaat tccaaataaa actgctgaat ctgtcaatca ggcgcttacg ttactattag
      781 gggagcatcg tattctgtcc attactgcag ataatggttc ggagttcaaa cgattgtctg
      841 aggtatttcc tgaggaacat atctactacg cacatgctta ctcttcatgg gagagaggtt
      901 caaatgaaaa tcataatcga ttaattcgga gatggttacc taaaggaacc aagaaaacga
      961 ctccgaaaga agtagctttt atcgaaaatt ggattaacaa ctaccctaaa aaatgcttgg
     1021 actacaagtc gccaagtgaa tttcttttgg gtggct
//
LOCUS       DAVBED010000105         1054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBED010000105 DAVBED010000000
VERSION     DAVBED010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.105"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQ547_002089"
     CDS             <1..555
                     /locus_tag="VQ547_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2543873.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQ547_002090"
     CDS             complement(503..1048)
                     /locus_tag="VQ547_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2543874.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBED010000106         1035 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBED010000106 DAVBED010000000
VERSION     DAVBED010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.106"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ547_002091"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ547_002091"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2543875.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBED010000107         1032 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBED010000107 DAVBED010000000
VERSION     DAVBED010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.107"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQ547_002092"
     CDS             complement(741..1001)
                     /locus_tag="VQ547_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543876.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT          341 a          196 c          168 g          327 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa tt
//
LOCUS       DAVBED010000108          922 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBED010000108 DAVBED010000000
VERSION     DAVBED010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.108"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQ547_002093"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQ547_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          336 a          139 c          172 g          275 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 actagcatag atgagcgctt gc
//
LOCUS       DAVBED010000109          830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBED010000109 DAVBED010000000
VERSION     DAVBED010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.109"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQ547_002094"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQ547_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBED010000110          704 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBED010000110 DAVBED010000000
VERSION     DAVBED010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.110"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            298..704
                     /locus_tag="VQ547_002095"
                     /pseudo
     CDS             298..704
                     /locus_tag="VQ547_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          217 a          126 c          133 g          228 t
ORIGIN      
        1 gttagttgtt tacttgcttc ataattcata gaactattat accatatttt gtttcgcagg
       61 aagtctattg aaaaatctcc agactagaga actcacggat agttcctaat ctggagattt
      121 cttatttgca cttttcttgt gcaactttag tccacggtaa ataggcctct aaaacctctt
      181 tgtttacgag agtttcctcg tttggaagac attctagaag ataggataga tatttctcgc
      241 tatttatact agactaaaat caaaaagcat tatacaatag tgatatgaaa tcaactgaag
      301 aaaagaaagc gctttaaaac cagtagacgt tttcataagg ttcgcttgat gtaccaagat
      361 gaggctggct tcggtagaat cagtaaactg ggatcttgtt ggtctccaat aggagtaggt
      421 ccacatgtcc atagtcacta tatacgagaa tttcactatt gttatggagc tgttgatgcc
      481 catacaggcg aatcattttt cttaatagct ggtggatgta atactgagtg gatgaacgcc
      541 tttttagaag agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat
      601 gctatatggc ataaatcaag taccttaaag actccgacta atattggttt tgcatttatt
      661 cctccataca caccagagat gaacccatcg aacaagtgtg gaaa
//
LOCUS       DAVBED010000111          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBED010000111 DAVBED010000000
VERSION     DAVBED010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.111"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ547_002096"
     tRNA            complement(74..147)
                     /locus_tag="VQ547_002096"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ547_002097"
     tRNA            complement(157..242)
                     /locus_tag="VQ547_002097"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ547_002098"
     tRNA            complement(250..321)
                     /locus_tag="VQ547_002098"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ547_002099"
     tRNA            complement(344..416)
                     /locus_tag="VQ547_002099"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ547_002100"
     tRNA            complement(435..516)
                     /locus_tag="VQ547_002100"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ547_002101"
     tRNA            complement(522..594)
                     /locus_tag="VQ547_002101"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ547_002102"
     tRNA            complement(619..691)
                     /locus_tag="VQ547_002102"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBED010000112          653 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBED010000112 DAVBED010000000
VERSION     DAVBED010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.112"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..>653)
                     /locus_tag="VQ547_002103"
     CDS             complement(<1..>653)
                     /locus_tag="VQ547_002103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543877.1"
                     /translation="ADALVLAEADALVLAEADALVDAEAEALVLAEADALVLAETEAL
                     VLAEADALVDAEAEALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALVD
                     ADSDAEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDAE
                     ADALVDAEAEALVDAEAEALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA"
BASE COUNT          164 a          218 c          147 g          124 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcagtctc agcaagcacc agtgcgtcgg cttcagcaag cacaagcgcc
      481 tcagcttcag catcaaccag tgcgtcagcc tcagcaagta ccagtgcctc agtctcagca
      541 agcaccagtg cgtcggcttc agcaagcaca agcgcctcag cttcagcatc aacgagtgcg
      601 tccgcttcag caagcacaag tgcgtcagcc tcagcaagta caagtgcgtc agc
//
LOCUS       DAVBED010000113          611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBED010000113 DAVBED010000000
VERSION     DAVBED010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.113"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQ547_002104"
     CDS             complement(189..>611)
                     /locus_tag="VQ547_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2543878.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBED010000114          603 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBED010000114 DAVBED010000000
VERSION     DAVBED010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.114"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
BASE COUNT          187 a          108 c          158 g          150 t
ORIGIN      
        1 gtcgtatatc tgaggtgtaa gtcctcggtg ggcacctgct accggtgaac ccaatagcga
       61 ttcccaagcc tgactatcgt gaggtagcag ggagaggaag ggatagcgaa atcgtggctc
      121 tacgaacagg aacgtgatag taaggcgtat atagcggata aggaggcttc aaactctaaa
      181 gtccaaaaag gtagtcgtaa cctatatgtg taaatcacga gagtaattga attcggacta
      241 aggtttgtgt gaaaaagata aatctttcta gagtctaaag actctgcgtc agatttccta
      301 ttttcactgt aaccttttaa cgtcctcata tcttgtataa acgaggaaag atgtacgact
      361 tatcccgtga ggtttcatga gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc
      421 cgagcccata gtagtgagga aacttccgta atggaagtgg agcgaagggg tgaatactca
      481 aacagtctgg ggagagactg tttgaggtct gtcgctagaa agagaaaacg acagatcgaa
      541 gtaatcctac ttcacttgtg tctgtaaaat gagtggtctg atagaactgg actttgacac
      601 gta
//
LOCUS       DAVBED010000115          563 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBED010000115 DAVBED010000000
VERSION     DAVBED010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.115"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQ547_002105"
     CDS             <1..223
                     /locus_tag="VQ547_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2543879.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
     gene            240..563
                     /locus_tag="VQ547_002106"
                     /pseudo
     CDS             240..563
                     /locus_tag="VQ547_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          213 a           88 c          103 g          159 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggta
      301 taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta gttccacagg
      361 attcattttt attgaaccga agtattcttg ataatataac tttaaagcac gaagttactt
      421 cacaaaagat agaggaagtt tgtaaagcag ttcaaatcta tgatgaaatc atggctatgc
      481 cgatgaaatt taatactatc atctcagaga tggggtcaaa tatttcaggt gggcaaaggc
      541 aacagatagc actggcacgt gca
//
LOCUS       DAVBED010000116          545 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBED010000116 DAVBED010000000
VERSION     DAVBED010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.116"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(42..545)
                     /locus_tag="VQ547_002107"
                     /pseudo
     CDS             complement(42..545)
                     /locus_tag="VQ547_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          155 a          130 c           92 g          168 t
ORIGIN      
        1 ttttagcagt cgatgcgtac tgttatagat tcaacgcact ataattgatg acgtttagct
       61 gtttccaaca aactcataat aatagctctt gctttagctc cttcaaaact ttgagaaaat
      121 aaccaccctc gcttttttaa actgagctta ggctaaaaga gtccactgga ctcttttact
      181 ccgtcccata accaatgatt taatggcgca ttcagctaga ttattggaaa ggaccagatg
      241 tccgtctttc aaaatagtct taaaggtttc tttatacttg aggctgtatt caattgccct
      301 tcctagtttt gaacccgata aaactgactg acgccggcac caagcaaaga aatcttccat
      361 taggttggag ctcttcttga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt
      421 ctctttccaa gaaaaataac tgatcacaat aagctaaacc tttagctcct aaggatgatt
      481 tatccgcttg cttgggggtc gcttcaaaaa acttccttct cacatgcgcc caacatccaa
      541 caagt
//
LOCUS       DAVBED010000117          526 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBED010000117 DAVBED010000000
VERSION     DAVBED010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.117"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(238..325)
                     /locus_tag="VQ547_002108"
     tRNA            complement(238..325)
                     /locus_tag="VQ547_002108"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ser,seq:gct)
     gene            complement(332..405)
                     /locus_tag="VQ547_002109"
     tRNA            complement(332..405)
                     /locus_tag="VQ547_002109"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(369..371),aa:Ile,seq:gat)
     gene            complement(441..511)
                     /locus_tag="VQ547_002110"
     tRNA            complement(441..511)
                     /locus_tag="VQ547_002110"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(477..479),aa:Gly,seq:tcc)
BASE COUNT          176 a          119 c           92 g          139 t
ORIGIN      
        1 gcaatgcctt tggttttcga aactttgaaa actttaaaaa acggattttt atcgctttga
       61 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttc ttcaacccac
      121 tacagttgac aaagagccat aaaaataact tcagattagt aattcaatta agttttacgg
      181 atctgaagct ttattgtctc taaaaataaa aaagagagtt acaaactctc attaaaacgg
      241 agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc
      301 tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga accaccgacc
      361 tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt aaaaaacttg
      421 gtaatttgaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa cagcttggaa
      481 ggctgtagtt ttaccactaa actacacccg cataaatact atcaat
//
LOCUS       DAVBED010000118          497 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBED010000118 DAVBED010000000
VERSION     DAVBED010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.118"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..>497)
                     /locus_tag="VQ547_002111"
     CDS             complement(<1..>497)
                     /locus_tag="VQ547_002111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543880.1"
                     /translation="ADALVDAEADALVLAEADALVDAEADALVLAEAEALVDAEADAL
                     VLAEAEALVDAEADALVLAEADALVLAEAEALVDAEAEALVDADSEALVDAEADALID
                     ADSEADVLAEAEALVDAEAEALVDADSEALVDAEAEADVDAEADALVDAEADALVDAE
                     AEALV"
BASE COUNT          122 a          162 c          112 g          101 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagc
//
LOCUS       DAVBED010000119          494 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBED010000119 DAVBED010000000
VERSION     DAVBED010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.119"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(53..126)
                     /locus_tag="VQ547_002112"
     tRNA            complement(53..126)
                     /locus_tag="VQ547_002112"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90..92),aa:Met,seq:cat)
     gene            complement(140..229)
                     /locus_tag="VQ547_002113"
     tRNA            complement(140..229)
                     /locus_tag="VQ547_002113"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(191..193),aa:Ser,seq:tga)
     gene            complement(312..385)
                     /locus_tag="VQ547_002114"
     tRNA            complement(312..385)
                     /locus_tag="VQ547_002114"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(349..351),aa:Ile,seq:gat)
     gene            complement(420..490)
                     /locus_tag="VQ547_002115"
     tRNA            complement(420..490)
                     /locus_tag="VQ547_002115"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(456..458),aa:Gly,seq:tcc)
BASE COUNT          141 a          137 c          109 g          107 t
ORIGIN      
        1 cgacacatgg agcttcaatc cattgctcta ccaactgagc taccgagcct tattgcggga
       61 gcaggatttg aacctacgac cttcgggtta tgagcccgac gagctaccga gctgctccat
      121 cccgcgttaa taatataaaa ggaggatgtg ggattcgaac ccacgcacgc ttttacacgc
      181 ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca aaatagttta
      241 tacgggaaca agcccgtgtc ctcttagtga acagataata ttccaatccc ctagtaatgg
      301 actaaacact atgggcacga gtggactcga accaccgacc tcacgcttat caggcgtgcg
      361 ctctaaccac ctgagctacg cgcccaagtc aaaaacttgg tacaaagaac aaagttcaaa
      421 gcgggtgacg agaatcgaac tcgcgacaac agcttggaag gctgtagttt taccactaaa
      481 ctacacccgc taaa
//
LOCUS       DAVBED010000120          393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBED010000120 DAVBED010000000
VERSION     DAVBED010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.120"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQ547_002116"
     CDS             <1..>393
                     /locus_tag="VQ547_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2543881.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBED010000121          392 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBED010000121 DAVBED010000000
VERSION     DAVBED010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.121"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            283..>392
                     /locus_tag="VQ547_002117"
     CDS             283..>392
                     /locus_tag="VQ547_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2543882.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT          143 a           53 c           70 g          126 t
ORIGIN      
        1 ggttacgata tgatcactga cttcgtcagt cttatctaca acctcaaaac tgtgttttga
       61 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaacagaaa
      121 aaatacttgg agtatttgtt tgtgtgttta tttttatata acaaactata aacaaaacaa
      181 aaatataaaa aaagagacaa aaaagaacag aaagcaattg acaacggttt catatagtgt
      241 tatacttatg gcataaagtt aatggaaaga agggaaaaac ttatggtatt agattatttc
      301 tttgacaaaa accttgtgtt ttgcttagaa gcggataatc aagaacaact ctttgatcag
      361 gttgcaactt tattggaaga acgagaaatt gt
//
LOCUS       DAVBED010000122          305 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBED010000122 DAVBED010000000
VERSION     DAVBED010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.122"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..245)
                     /locus_tag="VQ547_002118"
     CDS             complement(<1..245)
                     /locus_tag="VQ547_002118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543883.1"
                     /translation="MLALVDADVLADVLVLVDADVLAEAEALVLAEADALVLAEVDAD
                     SDALVDAEADALVDAEADALVLAEAEALVDADSDAEVL"
BASE COUNT           84 a           97 c           72 g           52 t
ORIGIN      
        1 agcacctcag cgtctgaatc ggcatcaacg agcgcctcag cttcagcaag taccagtgcg
       61 tcagcctcag cgtcaaccag tgcgtcagct tccgcatcaa cgagtgcgtc tgaatcggca
      121 tcaacctcag caagtacaag tgcatcggct tcagcaagca ccagtgcttc ggcttcagca
      181 agcacgtcag catcaacaag cacaagtaca tcggcaagca cgtcagcatc gacaagtgca
      241 agcacatcgg cgtcaacaag tgcaagtacg tcagcatctg aatcggcctc aaccagtgcg
      301 tcgac
//
LOCUS       DAVBED010000123          293 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBED010000123 DAVBED010000000
VERSION     DAVBED010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.123"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..>293)
                     /locus_tag="VQ547_002119"
     CDS             complement(<1..>293)
                     /locus_tag="VQ547_002119"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543884.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVEADSDAEVLAEAEALVLAEAEALVDAEAEALVLAEADALVEAEA"
BASE COUNT           66 a          101 c           68 g           58 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtact agcgcctcag cttcagcaag cacctcagcg
      121 tctgaatcgg cctcaacgag cgcctcagct tcagcaagta ccagtgcgtc agcctcagca
      181 agtaccagtg cttcagcctc agcgtcgaca agtgcctcgg cttcagcaag tacctcagcg
      241 tctgaatcgg cctcaaccag tgcatctgaa tcggcctcaa ccagtgcctc agc
//
LOCUS       DAVBED010000124          288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBED010000124 DAVBED010000000
VERSION     DAVBED010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.124"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQ547_002120"
     CDS             <1..>288
                     /locus_tag="VQ547_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2543885.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVBED010000125          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBED010000125 DAVBED010000000
VERSION     DAVBED010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.125"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..>284)
                     /locus_tag="VQ547_002121"
     CDS             complement(<1..>284)
                     /locus_tag="VQ547_002121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543886.1"
                     /translation="SDALVLAEADALVLAEADALVDAEAEALVLADSDALVLAEADAL
                     VLAEADALVDAEADALVDAEADALVDAEAEALVLAEAEALVDADSDALVEA"
BASE COUNT           77 a           91 c           63 g           53 t
ORIGIN      
        1 gcctcaacca gtgcatctga atcggcatca accagtgcct cagcctcagc aagtactagc
       61 gcctcagctt cagcatcaac gagtgcatca gcttccgcat caacaagtgc atcagcttcc
      121 gcatcaacga gtgcatcggc ttcagcaagc acaagtgcgt cagcctcagc aagtaccagt
      181 gcatcagagt cagcaagtac cagtgcttca gcttcagcat caacgagtgc gtccgcttca
      241 gcaagcacaa gtgcgtcagc ctcagcaagt accagtgcat caga
//
LOCUS       DAVBED010000126          279 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBED010000126 DAVBED010000000
VERSION     DAVBED010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.126"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(<1..>279)
                     /locus_tag="VQ547_002122"
     CDS             complement(<1..>279)
                     /locus_tag="VQ547_002122"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543887.1"
                     /translation="AEAEALVLAEAEALVDAEAEALVDAEADALVDAEAEALVDAEAE
                     ADVDADSDALVLAEAEALVLAEADALVEADSDALVEAEADALVDAEAEA"
BASE COUNT           59 a           93 c           71 g           56 t
ORIGIN      
        1 gcctcggctt cagcatcaac gagtgcgtca gcttcagcct caacgagtgc gtctgagtca
       61 gcctcaacga gtgcgtcggc ttcagcaagt accagtgctt cggcctcagc aagcacaagt
      121 gcgtctgaat ccgcatcaac gtctgcctca gcctcagcat cgacaagcgc ttcagcttca
      181 gcgtcgacaa gtgcgtcagc ctcagcatcg acaagcgctt cagcttcagc gtcgacaagt
      241 gcttcggctt cagcaagcac cagtgcctcg gcttcagcg
//
LOCUS       DAVBED010000127          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBED010000127 DAVBED010000000
VERSION     DAVBED010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.127"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQ547_002123"
     CDS             <1..>277
                     /locus_tag="VQ547_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2543888.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBED010000128          274 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBED010000128 DAVBED010000000
VERSION     DAVBED010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.128"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            complement(1..274)
                     /locus_tag="VQ547_002124"
                     /pseudo
     CDS             complement(1..274)
                     /locus_tag="VQ547_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT           87 a           43 c           57 g           87 t
ORIGIN      
        1 ttctggaaat gaaaaagcaa gagctgatag agttgatagt ggtgtttcaa gtcttccgaa
       61 taactcaaaa gcttgtttaa aatctcttta ttggttcaat gcatacgaaa agtaggacga
      121 taaaaatgtt tatcactcag tttacgacta tcctgttgaa tgagtttcca gtagcgcttg
      181 atagccttgt attcatggga ttttcgatga aactgattta tgatttgaac acgcacacga
      241 ctcatagcac ggctaagatg ttgtacaatg tgaa
//
LOCUS       DAVBED010000129          229 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 037
            SAMEA1678106-rid20185403.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBED010000129 DAVBED010000000
VERSION     DAVBED010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678106
            Sequence Read Archive: ERR226402
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980217.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980217.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:16:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,125
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 65 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 28 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678106-rid20185403.denovo.129"
                     /strain="KS 037"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQ547_002125"
     CDS             <1..>229
                     /locus_tag="VQ547_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2543889.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
